Registered substances

Registered substances

Registered substances

Please note:

As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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(6a,8xi,11b,14xi,16a)-6,9-difluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4- dien-21-yl benzoate
938-716-9 - No longer Valid Intermediate Individual No longer valid 04-02-2013 View substance registered dossier
(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)
939-998-6 - Active Intermediate Individual Intermediate use only 18-12-2013 View substance registered dossier
(6R,7R)-7-amino-3-(5H-imidazo[1,2-b]pyridazin-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydroiodide
606-382-0 197897-11-3 Cease Manufacture Intermediate Individual Cease manufacture 20-04-2018 View substance registered dossier
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
700-301-3 69739-16-8 Cease Manufacture Intermediate Individual Cease manufacture 04-06-2009 View substance registered dossier
(6R-trans)-1-((7-ammonio-2-carboxylato-8-oxo-5-thia-1-azabicyclo-[4.2.0]oct-2-en-3-yl)methyl)pyridinium iodide
423-260-0 100988-63-4 Cease Manufacture NONS Individual Cease manufacture 29-10-2012 View substance registered dossier
(6R-trans)-7-amino-3-[([5-(carboxymethyl)-4-methyl-2-thiazolyl]thio)methyl]-8-oxo- 5-thia-1-azabicyclo-[4.2.0]oct-2-en-2-carboxylic acid
TACS
403-690-5 111298-82-9 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide
431-140-4 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(6β)-6,19-epoxyandrost-4-ene-3,17-dione
433-490-3 6563-83-3 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
(7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate
642-947-8 415927-29-6 Active Intermediate Individual Intermediate use only 04-04-2018 View substance registered dossier
(8R,9S,13S,14S)-3-(Benzyloxy)-13-methyl-6,7,8,9,11,12,13,14 ,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,2`-[1,3]dioxolane]
844-245-9 162784-26-1 Active Intermediate Individual Intermediate use only 09-11-2021 View substance registered dossier
(8R,9S,13S,14S)-3-benzyloxy)-13-methyl-6,7,8,9,11,12,13,14- octahydrospiro[cyclopenta[a]phenanthrene-17,2`[1,3]dioxolane]
844-243-8 534572-67-3 Active Intermediate Individual Intermediate use only 05-11-2021 View substance registered dossier
(9S)-9-amino-9-deoxyerythromycin
E.M.A.
406-790-7 26116-56-3 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(Bromomethyl)cyclobutane
700-027-4 17247-58-4 Cease Manufacture Intermediate Individual Cease manufacture 31-08-2011 View substance registered dossier
(C12-C14)tert-alkylammonium methylphosphonate
CD 23-404
404-750-3 119415-07-5 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(C14-C30-alkyl)phenyl-3-tolyliodonium trifluoromethansulfonate
DOW CORNING(R) 2-7103 CATALYST
424-410-8 172928-53-9 No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
(C14/C16/C18) n-alkyl (of non animal origin)benzyl dimethyl ammonium chloride compound with bentonite
TIXOGEL VZ-V
436-020-5 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(chloromethyl)bis(4-fluorophenyl)methylsilane
H6572
401-200-4 85491-26-5 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(chloromethyl)cyclopropane
227-632-1 5911-08-0 Active Intermediate Individual Intermediate use only 29-03-2018 View substance registered dossier
(cyclopropylmethoxy)acetic acid
853-795-9 246869-08-9 Active Intermediate Individual Intermediate use only 18-03-2021 View substance registered dossier
(E)-(6,10-dimethylundeca-1,5,9-trien-2-yl)cyclopropane
834-085-8 714230-50-9 Active Intermediate Individual Intermediate use only 15-02-2022 View substance registered dossier
(E)-1,1,1,2,3,4,5,5,5-Nonafluoro-4-(trifluoromethyl)pent-2-ene
807-113-1 3709-71-5 No longer Valid Intermediate Individual No longer valid 25-05-2018 View substance registered dossier
(E)-3,7-dimethyl-2,6-octadienylhexadecanoate
HEXAROSE
421-370-3 3681-73-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(E)-3-(2-chlorophenyl)-2-(4-fluorophenyl)propenal
DPP
410-980-5 112704-51-5 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(E)-3-(4-(4-fluorophenyl)-5-methoxymethyl-2,6-bis(1-methoxymethyl)pyridin-3-yl)prop-2-enal
PYRIDYLACROLEIN
426-330-9 177964-68-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(E)-3-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol
CP-166,221
428-010-4 82413-20-5 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(E)-3-[6-(p-toluoyl)-2-pyridyl]acrylic acid
302-128-5 94094-27-6 No longer Valid Intermediate Individual No longer valid 22-10-2018 View substance registered dossier
(E)-3-methyl-5-cyclopentadecen-1-one
429-900-5 82356-51-2 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
(E)-4-(3a,4,5,6,7,7a-hexahydro-1H-4,7-methanoinden-5-yl)-3-methylbut-3-en-2-ol;(E)-4-(3a,4,5,6,7,7a-hexahydro-3H-4,7-methanoinden-5-yl)-3-methylbut-3-en-2-ol;1-(1,3a,4,6,7,7a-hexahydro-4,7-methanoinden-5-ylidene)pentan-3-ol;1-(3,3a,4,6,7,7a-hexahydro-4,7-methanoinden-5-ylidene)pentan-3-ol;4-(3,3a,4,6,7,7a-hexahydro-4,7-methanoinden-5-ylidene)-3-methylbutan-2-ol;reaction mass of: 4-(1,3a,4,6,7,7a-hexahydro-4,7-methanoinden-5-ylidene)-3-methylbutan-2-ol
444-430-0 - Active NONS Individual Tonnage data confidential 07-04-2011 View substance registered dossier
(E)-N-((dialkylamino)alkylene)-3,5-bis(polyfluoroalkyl)benzamide
- - Active Intermediate Individual Intermediate use only 08-11-2016 View substance registered dossier
(E,E)-3,7,11-trimethyldodeca-1,4,6,10-tetraen-3-ol
423-240-1 125474-34-2 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(E,Z)-4-chlorophenyl(cyclopropyl)ketone O-(4-nitrophenylmethyl)oxime
NCC ETHER
406-100-4 94097-88-8 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(E-E )-3,3'-(1,4-phenylenedimethylidene)bis(2-oxobornane-10-sulfonic acid)
MEXORYL SX; SX 32
410-960-6 92761-26-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(ethyl-3-oxobutanoato-O'1,O'3)(2-dimethylaminoethanolato)(1-methoxypropan-2-olato)aluminium(III), dimerised
AOC 1020X
402-370-2 149057-70-5 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(hydroxyethyl)urea
215-304-0 1320-51-0 Active Full Individual ≥ 10 to < 100 tonnes 23-04-2021 View substance registered dossier
(imidazol-5-yl)ethyl-3-aminopropionamide dihydrochloride
CHLORHYDRATE DE CARCININE
415-470-6 57022-38-5 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
(methoxymethyl)triphenylphosphonium chloride
223-664-5 4009-98-7 Active Intermediate Individual Intermediate use only 16-09-2013 View substance registered dossier
(p-chlorophenyl)metaboric acid
216-845-5 1679-18-1 Active Intermediate Individual Intermediate use only 24-04-2018 View substance registered dossier
(pentabromophenyl)methyl acrylate
261-767-7 59447-55-1 Active Full Individual ≥ 100 to < 1 000 tonnes 11-12-2012 View substance registered dossier
(R)-1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline, compound with (S)-2-(6-methoxy-naphthalen-2-yl)-propionic acid
941-846-9 - Active Intermediate Individual Intermediate use only 17-03-2015 View substance registered dossier
(R)-1-hydroxy-1-phenylacetone
217-285-4 1798-60-3 Active Intermediate Individual Intermediate use only 08-05-2013 View substance registered dossier
(R)-2-(2,5-difluorophenyl)pyrrolidine (R)-2-hydroxysuccinate
845-727-1 1919868-77-1 Active Intermediate Individual Intermediate use only 18-01-2022 View substance registered dossier
(R)-2-(4-hydroxyphenoxy)propanoic acid
D-HPPA; HPOPS
407-960-3 94050-90-5 No longer Valid Intermediate Individual No longer valid 28-09-2010 View substance registered dossier
(R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propionic acid
440-090-2 86123-10-6 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
(R)-2-acetamido-3-naphthyl-2-yl-propionic acid
(R)-2-ACETAMIDO-3-NAPHTHYLEN-2-YL-PROPIONIC ACID
440-450-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-2-tert-butoxycarbonylamino-3-(4-chlorophenyl)propionic acid
(R)-2-TERT-BUTOXYCARBONYLAMINO-3-(4-CHLOROPHENYL)-PROPIONIC ACID
438-070-3 57292-44-1 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-2-tert-butoxycarbonylamino-3-(pyridin-3-yl)propionic acid
(R)-2-TERT-BUTOXYCARBONYLAMINO-3-(PYRIDIN-3-YL) PROPIONIC ACID
441-200-1 98266-33-2 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-3-[(1-methylpyrrolidin-2-yl)methyl]-5-[2-(phenylsulfonyl)ethenyl]-1H-indole
430-560-5 180637-89-2 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-3-chloropropane-1,2-diol
435-560-9 57090-45-6 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(R)-4-(4-dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemi (2R, 3R)-2,3-bis((4-methylbenzoyl)oxy)succinoate
949-784-4 - Active Intermediate Individual Intermediate use only 25-03-2019 View substance registered dossier
(R)-5-bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole
UK-111,975
422-390-5 143322-57-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Glaxo Operations UK Glaxo Wellcome House Berkeley Avenue UB6 0NN Greenford Middlesex United Kingdom United Kingdom No longer Valid (6a,8xi,11b,14xi,16a)-6,9-difluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4- dien-21-yl benzoate 938-716-9 - 2021 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3) 939-998-6 - - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-7-amino-3-(5H-imidazo[1,2-b]pyridazin-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydroiodide 606-382-0 197897-11-3 2021 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 700-301-3 69739-16-8 2021 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R-trans)-1-((7-ammonio-2-carboxylato-8-oxo-5-thia-1-azabicyclo-[4.2.0]oct-2-en-3-yl)methyl)pyridinium iodide 423-260-0 100988-63-4 2021 View substance registered dossier
Sanofi Aventis Deutschland GmbH Industriepark Höchst H 831 (Room A0472) z.Hd. Hr. Dr. Schwind 65926 Frankfurt am Main Germany Germany Active (6R-trans)-7-amino-3-[([5-(carboxymethyl)-4-methyl-2-thiazolyl]thio)methyl]-8-oxo- 5-thia-1-azabicyclo-[4.2.0]oct-2-en-2-carboxylic acid 403-690-5 111298-82-9 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide 431-140-4 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active (6β)-6,19-epoxyandrost-4-ene-3,17-dione 433-490-3 6563-83-3 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate 642-947-8 415927-29-6 - View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (8R,9S,13S,14S)-3-(Benzyloxy)-13-methyl-6,7,8,9,11,12,13,14 ,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,2`-[1,3]dioxolane] 844-245-9 162784-26-1 - View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (8R,9S,13S,14S)-3-benzyloxy)-13-methyl-6,7,8,9,11,12,13,14- octahydrospiro[cyclopenta[a]phenanthrene-17,2`[1,3]dioxolane] 844-243-8 534572-67-3 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (9S)-9-amino-9-deoxyerythromycin 406-790-7 26116-56-3 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture (Bromomethyl)cyclobutane 700-027-4 17247-58-4 2015 View substance registered dossier
BASF Lampertheim GmbH Chemiestrasse 22 68619 Lampertheim Germany Germany Cease Manufacture (C12-C14)tert-alkylammonium methylphosphonate 404-750-3 119415-07-5 2018 View substance registered dossier
- - - - (C14-C30-alkyl)phenyl-3-tolyliodonium trifluoromethansulfonate 424-410-8 172928-53-9 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (C14/C16/C18) n-alkyl (of non animal origin)benzyl dimethyl ammonium chloride compound with bentonite 436-020-5 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (chloromethyl)bis(4-fluorophenyl)methylsilane 401-200-4 85491-26-5 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active (chloromethyl)cyclopropane 227-632-1 5911-08-0 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (cyclopropylmethoxy)acetic acid 853-795-9 246869-08-9 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (E)-(6,10-dimethylundeca-1,5,9-trien-2-yl)cyclopropane 834-085-8 714230-50-9 - View substance registered dossier
F2 Chemicals Ltd Lea Lane Lea Town PR4 0RZ Preston Lancashire United Kingdom United Kingdom No longer Valid (E)-1,1,1,2,3,4,5,5,5-Nonafluoro-4-(trifluoromethyl)pent-2-ene 807-113-1 3709-71-5 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (E)-3,7-dimethyl-2,6-octadienylhexadecanoate 421-370-3 3681-73-0 - View substance registered dossier
BASF Schwarzheide GmbH Schipkauer Str. 1 01987 Schwarzheide Brandenburg Germany Germany Cease Manufacture (E)-3-(2-chlorophenyl)-2-(4-fluorophenyl)propenal 410-980-5 112704-51-5 2018 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (E)-3-(4-(4-fluorophenyl)-5-methoxymethyl-2,6-bis(1-methoxymethyl)pyridin-3-yl)prop-2-enal 426-330-9 177964-68-0 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (E)-3-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol 428-010-4 82413-20-5 - View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom No longer Valid (E)-3-[6-(p-toluoyl)-2-pyridyl]acrylic acid 302-128-5 94094-27-6 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (E)-3-methyl-5-cyclopentadecen-1-one 429-900-5 82356-51-2 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (E)-4-(3a,4,5,6,7,7a-hexahydro-1H-4,7-methanoinden-5-yl)-3-methylbut-3-en-2-ol;(E)-4-(3a,4,5,6,7,7a-hexahydro-3H-4,7-methanoinden-5-yl)-3-methylbut-3-en-2-ol;1-(1,3a,4,6,7,7a-hexahydro-4,7-methanoinden-5-ylidene)pentan-3-ol;1-(3,3a,4,6,7,7a-hexahydro-4,7-methanoinden-5-ylidene)pentan-3-ol;4-(3,3a,4,6,7,7a-hexahydro-4,7-methanoinden-5-ylidene)-3-methylbutan-2-ol;reaction mass of: 4-(1,3a,4,6,7,7a-hexahydro-4,7-methanoinden-5-ylidene)-3-methylbutan-2-ol 444-430-0 - 2011 View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active (E)-N-((dialkylamino)alkylene)-3,5-bis(polyfluoroalkyl)benzamide - - 2016 View substance registered dossier
DSM Nutritional Products France SAS 1 boulevard d'Alsace F-68128 Village-Neuf France France Active (E,E)-3,7,11-trimethyldodeca-1,4,6,10-tetraen-3-ol 423-240-1 125474-34-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (E,Z)-4-chlorophenyl(cyclopropyl)ketone O-(4-nitrophenylmethyl)oxime 406-100-4 94097-88-8 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (E-E )-3,3'-(1,4-phenylenedimethylidene)bis(2-oxobornane-10-sulfonic acid) 410-960-6 92761-26-7 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (ethyl-3-oxobutanoato-O'1,O'3)(2-dimethylaminoethanolato)(1-methoxypropan-2-olato)aluminium(III), dimerised 402-370-2 149057-70-5 - View substance registered dossier
Nouryon Surface Chemistry AB Box 47067 40258 Göteborg Sweden Sweden Active (hydroxyethyl)urea 215-304-0 1320-51-0 2013; 2021 View substance registered dossier
- - - - (imidazol-5-yl)ethyl-3-aminopropionamide dihydrochloride 415-470-6 57022-38-5 - View substance registered dossier
CARBOGEN AMCIS B.V. Nieuweweg 2a 3901 BE Veenendaal Netherlands Netherlands Active (methoxymethyl)triphenylphosphonium chloride 223-664-5 4009-98-7 - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active (p-chlorophenyl)metaboric acid 216-845-5 1679-18-1 - View substance registered dossier
ICL Europe Coöperatief U.A. (OR1) Koningin Wilhelminaplein 30 Prinsenhof 1062 KR Amsterdam Netherlands Netherlands Active (pentabromophenyl)methyl acrylate 261-767-7 59447-55-1 - View substance registered dossier
RECORDATI SPA Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy Italy Active (R)-1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline, compound with (S)-2-(6-methoxy-naphthalen-2-yl)-propionic acid 941-846-9 - - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active (R)-1-hydroxy-1-phenylacetone 217-285-4 1798-60-3 2013 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active (R)-2-(2,5-difluorophenyl)pyrrolidine (R)-2-hydroxysuccinate 845-727-1 1919868-77-1 2022 View substance registered dossier
NuFarm Limited Wyke Lane BD12 9EJ Wyke West Yorkshire United Kingdom United Kingdom No longer Valid (R)-2-(4-hydroxyphenoxy)propanoic acid 407-960-3 94050-90-5 2021 View substance registered dossier
- - - - (R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propionic acid 440-090-2 86123-10-6 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-2-acetamido-3-naphthyl-2-yl-propionic acid 440-450-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-2-tert-butoxycarbonylamino-3-(4-chlorophenyl)propionic acid 438-070-3 57292-44-1 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-2-tert-butoxycarbonylamino-3-(pyridin-3-yl)propionic acid 441-200-1 98266-33-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-3-[(1-methylpyrrolidin-2-yl)methyl]-5-[2-(phenylsulfonyl)ethenyl]-1H-indole 430-560-5 180637-89-2 - View substance registered dossier
COVANCE CLINICAL DEVELOPMENT SA 171 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Cease Manufacture (R)-3-chloropropane-1,2-diol 435-560-9 57090-45-6 2012 View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active (R)-4-(4-dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemi (2R, 3R)-2,3-bis((4-methylbenzoyl)oxy)succinoate 949-784-4 - - View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active (R)-5-bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole 422-390-5 143322-57-0 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland No longer Valid (R)-5-bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole 422-390-5 143322-57-0 2013 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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