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Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The REACH Registered substance portal was updated on 9th November 2020; the REACH registered factsheets were further updated on 21st December 2020. Details of the improvements can be found at Dissemination Platform Updates. Reprocessing the entire dataset is ongoing since 21 December 2020. ECHA is making all possible efforts to make the improvements and additional data visible with the shortest delay.
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
Last updated 15 June 2021. Database contains 23307 unique substances and contains information from 103785 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
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Uses and exposure
Life cycle:
  • Consumer Uses
  • Article service life
  • Widespread uses by professional workers
  • Formulation or re-packing
  • Uses at industrial sites
  • Manufacture
Category:
Details
4-(trans-4-propylcyclohexyl)phenyl acetic acid
435-100-7 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-({6-AMINO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILE
458-850-7 - Active NONS Joint Tonnage data confidential 23-05-2018 View substance registered dossier
4-[(3-isobutoxy-1-isobutoxycarbonyl-3-oxopropyl)(3-octyloxypropyl)amino]-4-oxobutyric acid;reaction mass of: 4-[(3-decyloxypropyl)(3-isobutoxy-1-isobutoxycarbonyl-3-oxopropyl)amino]-4-oxobutyric acid
423-750-4 - Active NONS Individual Tonnage data confidential 11-04-2012 View substance registered dossier
4-[(4,6-bis{[3-(diethylamino)propyl]amino}-heteromonocycle-2-yl)amino]-N-[2-(4,5,6,7-tetrachloro-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)quinolin-8-yl]benzenesulfonamide
- - Active Full Individual ≥ 1 to < 10 tonnes 05-10-2011 View substance registered dossier
4-[(4-(aminoiminomethyl)phenyl)amino]-4-oxobutanoic acid hydrochloride
430-340-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-[(4-chloro-6-{[(3 or 4)-sulfophenyl]amino}-1,3,5-triazin-2-yl)amino]-2-{[1-ethyl-2-hydroxy-4-methyl-6-oxo-5-(sulfonatomethyl)-1,6-dihydropyridin-3-yl]diazenyl}benzenesulfonic acid, lithium sodium salts
942-795-5 - Active Full Individual ≥ 10 to < 100 tonnes 01-10-2019 View substance registered dossier
4-[(4-Fluorophenylimino)methyl]phenol
438-950-7 - Active Intermediate Joint Intermediate use only 25-07-2019 View substance registered dossier
4-[(4-Fluorophenylimino)methyl]phenol
438-950-7 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-[(4-{[4-({5-[2-(acryloyloxy) ethoxy]-5-oxoalkanoyl}oxy) benzoyl]oxy}-2-methylaroxy)carbonyl] aryl 2-(acryloyloxy) ethyl alkandioate
- - Active Full Joint Tonnage data confidential 04-12-2017 View substance registered dossier
4-[(6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile
928-806-6 - Active Full Joint ≥ 1 to < 10 tonnes 29-05-2018 View substance registered dossier
4-[({(3R,3aR,6S,6aR)-6-[(4-{[4-({[4-(acryloyloxy)butoxy]carbonyl}oxy)benzoyl]oxy}benzoyl)oxy]hexahydrofuro[3,2-b]furan-3-yl}oxy)carbonyl]phenyl 4-({[4-(acryloyloxy)butoxy]carbonyl}oxy)benzoate
431-360-0 - Active NONS Individual Tonnage data confidential 02-08-2011 View substance registered dossier
4-[2-((6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-ylsulfanyl)thiazole-4-yl]-1-methyl-pyridiniumchloride monohydrochloride
447-990-4 - Active Intermediate Joint Intermediate use only 16-10-2019 View substance registered dossier
4-[2-((6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-ylsulfanyl)thiazole-4-yl]-1-methyl-pyridiniumchloride monohydrochloride
447-990-4 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-[2-(Cyclopropylmethoxy)ethyl]phenol
440-910-9 - Active Intermediate Joint Intermediate use only 12-10-2018 View substance registered dossier
4-[2-(Cyclopropylmethoxy)ethyl]phenol
440-910-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-[4-[4-[(3R, 5R)[5-(2,4-difluorophenyl) tetrahydro-5-(1H-1,2,4-triazol-1-yl-methyl)-furan-3-yl]methyloxy]phenyl]-1-piperazinyl]phenyl-2-[(1S,2S)(1-ethyl-2-phenylmethoxypropyl)]-2,4-dihydro-3Htriazol-3-one
938-153-9 - Active Full Joint ≥ 10 to < 100 tonnes 27-06-2017 View substance registered dossier
4-[bis(2-tert-butyl-4-hydroxy-6-methylphenyl)methyl]phenyl 6-diazo-5-oxo-5,6-dihydronaphthalene-1-sulfonate
451-040-4 - Active NONS Individual Tonnage data confidential 27-11-2012 View substance registered dossier
4-[difluoro(3,4,5-trifluorophenoxy)methyl]-2',3,5-trifluoro-4''-pentyl-1,1':4',1''-terphenyl
935-977-0 - Active Full Joint ≥ 0 to < 10 tonnes 16-10-2019 View substance registered dossier
4-acetilammino-N-((1-etil-2pirrolidinil)metil) -5 etilsulfonil-2-metossi benzamide
925-003-2 - Active Intermediate Joint Intermediate use only 27-03-2018 View substance registered dossier
4-acetyloxy-5β,20-epoxy-1,2α,4,7β,10β,13α-hexahydroxy-9-oxotax-11-en-2-yl benzoate
418-680-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-Amino-5-chloro-2,1,3-benzothiodiazole
457-490-8 - Active Intermediate Individual Intermediate use only 01-04-2015 View substance registered dossier
4-amino-5-ethyl-1-(2-methoxyethyl)-1H-Pyrazole-3-carboxamide
438-910-9 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
4-amino-6-((E)-(4-(4-(ethenylsulfonyl)butanoyl)amino)-diazenyl)-3-((E)-4- (ethenylsulfonyl)-diazenyl)-5-hydroxypolycarbocyclo, polysulfonate, polyphenyl, sodium salt
401-000-7 - Active Full Joint ≥ 10 to < 100 tonnes 15-12-2014 View substance registered dossier
4-amino-6-((E)-(4-(4-(ethenylsulfonyl)butanoyl)amino)-diazenyl)-3-((E)-4- (ethenylsulfonyl)-diazenyl)-5-hydroxypolycarbocyclo, polysulfonate, polyphenyl, sodium salt
401-000-7 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-bromo-2,3',4',5'-tetrafluoro-1,1'-biphenyl
936-926-5 - Active Intermediate Joint Intermediate use only 19-02-2018 View substance registered dossier
4-Butoxy-2,3-difluor-4'-methyl-1,1'-biphenyl
938-422-0 - Active Full Joint ≥ 0 to < 10 tonnes 13-05-2019 View substance registered dossier
4-chloro-6-methoxypyrimidine
435-030-7 - Active Intermediate Individual Intermediate use only 10-12-2020 View substance registered dossier
4-chloromethyl-4''-ethyl-2'-fluoro-[1,1':4',1''-terphenyl]
936-119-8 - Active Full Joint ≥ 1 to < 10 tonnes 07-12-2018 View substance registered dossier
4-cis-ethyl-4'-trans-propyl-[1,1'-bicyclohexyl]
935-545-1 - Active Intermediate Joint Intermediate use only 19-02-2018 View substance registered dossier
4-CPH
428-130-7 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-ethoxy-2,3-difluoro-4'-(trans-4-propylcyclohexyl)-1,1'-biphenyl
921-136-5 - Active Full Joint ≥ 0 to < 10 tonnes 16-04-2018 View substance registered dossier
4-ethyl-1,3-dioxolan-2-one
403-780-4 - Active NONS Joint Tonnage data confidential 01-02-2011 View substance registered dossier
4-ethyl-2-fluoro-4'-(2-(trans-4-propylcyclohexyl)ethyl)biphenyl
433-190-2 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-Fluoro-3-hydroxybenzoic acid
434-190-5 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
4-Fluoro-3-hydroxybenzoic acid
434-190-5 - Active Intermediate Joint Intermediate use only 28-08-2019 View substance registered dossier
4-hexadecyl-1-phenylpyrazolidin-3-one
430-840-7 - Active NONS Joint Tonnage data confidential 10-03-2011 View substance registered dossier
4-Hydroxy-3,5-dimethylbenzonitrile
452-810-2 - Active Full Joint ≥ 1 to < 10 tonnes 23-05-2018 View substance registered dossier
4-Hydroxy-3,5-dimethylbenzonitrile
452-810-2 - Cease Manufacture NONS Individual Cease manufacture 14-09-2010 View substance registered dossier
4-hydroxy-3-methyl-5-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]pentan-2-one
949-712-1 - Active Intermediate Joint Intermediate use only 11-02-2019 View substance registered dossier
4-hydroxybutan-2-one + 3-(hydroxymethyl)but-3-en-2-one
908-868-0 - Active Intermediate Joint Intermediate use only 22-01-2020 View substance registered dossier
4-hydroxybutane-1-sulfonic acid
928-903-3 - Active Intermediate Individual Intermediate use only 29-04-2015 View substance registered dossier
4-hydroxyphenyl 4-(allyloxy)benzoate
433-210-1 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-hydroxystyrene, 4-tbutoxy styrene and styrene copolymer
433-660-7 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-Isobutylbenzaldehyde
464-400-0 - Active NONS Joint Tonnage data confidential 22-07-2014 View substance registered dossier
4-Methoxy-5-(3-morpholin-4-yl-propoxy)-2-nitro-benzonitrile
936-067-6 - Active Intermediate Joint Intermediate use only 24-10-2017 View substance registered dossier
4-methoxybenzyl 3-chloromethyl-5-oxo-6-phenylacetamido-(2H)5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
403-040-0 - Active Intermediate Individual Intermediate use only 16-11-2011 View substance registered dossier
4-methoxybenzyl 3-chloromethyl-5-oxo-6-phenylacetamido-(2H)5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
403-040-0 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-Methoxycarbonyl-2-methylthiophen-3-yl-ammonium hydrochloride
929-732-7 - Active Intermediate Joint Intermediate use only 21-02-2013 View substance registered dossier
4-Methyl-2-propylbenzimidazole-6-carboxylic acid
424-450-6 - Active Intermediate Individual Intermediate use only 21-04-2010 View substance registered dossier
4-Methyl-2-propylbenzimidazole-6-carboxylic acid
424-450-6 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 4-(trans-4-propylcyclohexyl)phenyl acetic acid 435-100-7 - - View substance registered dossier
Janssen Pharmaceutical Science Unlimited Company Little Island County NA Cork Ireland Ireland Active 4-({6-AMINO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILE 458-850-7 - 2018 View substance registered dossier
King Industries International Science Park 402 1098 XH Amsterdam Amsterdam Netherlands Netherlands Active 4-[(3-isobutoxy-1-isobutoxycarbonyl-3-oxopropyl)(3-octyloxypropyl)amino]-4-oxobutyric acid;reaction mass of: 4-[(3-decyloxypropyl)(3-isobutoxy-1-isobutoxycarbonyl-3-oxopropyl)amino]-4-oxobutyric acid 423-750-4 - 2012 View substance registered dossier
TOYO INK EUROPE SPECIALTY CHEMICALS Boulevard Dambourney 76350 Oissel France France Active 4-[(4,6-bis{[3-(diethylamino)propyl]amino}-heteromonocycle-2-yl)amino]-N-[2-(4,5,6,7-tetrachloro-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)quinolin-8-yl]benzenesulfonamide - - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-[(4-(aminoiminomethyl)phenyl)amino]-4-oxobutanoic acid hydrochloride 430-340-9 - - View substance registered dossier
Only representative (No publishable name) - - Active 4-[(4-chloro-6-{[(3 or 4)-sulfophenyl]amino}-1,3,5-triazin-2-yl)amino]-2-{[1-ethyl-2-hydroxy-4-methyl-6-oxo-5-(sulfonatomethyl)-1,6-dihydropyridin-3-yl]diazenyl}benzenesulfonic acid, lithium sodium salts 942-795-5 - 2017; 2019 View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active 4-[(4-Fluorophenylimino)methyl]phenol 438-950-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 4-[(4-Fluorophenylimino)methyl]phenol 438-950-7 - - View substance registered dossier
Rolic Technologies B.V. Luchthavenweg 10 5657 EB Eindhoven Netherlands Netherlands Active 4-[(4-{[4-({5-[2-(acryloyloxy) ethoxy]-5-oxoalkanoyl}oxy) benzoyl]oxy}-2-methylaroxy)carbonyl] aryl 2-(acryloyloxy) ethyl alkandioate - - - View substance registered dossier
Janssen Pharmaceutical Science Unlimited Company Little Island County NA Cork Ireland Ireland Active 4-[(6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile 928-806-6 - - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 4-[({(3R,3aR,6S,6aR)-6-[(4-{[4-({[4-(acryloyloxy)butoxy]carbonyl}oxy)benzoyl]oxy}benzoyl)oxy]hexahydrofuro[3,2-b]furan-3-yl}oxy)carbonyl]phenyl 4-({[4-(acryloyloxy)butoxy]carbonyl}oxy)benzoate 431-360-0 - 2011 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active 4-[2-((6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-ylsulfanyl)thiazole-4-yl]-1-methyl-pyridiniumchloride monohydrochloride 447-990-4 - 2019 View substance registered dossier
- - - - 4-[2-((6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-ylsulfanyl)thiazole-4-yl]-1-methyl-pyridiniumchloride monohydrochloride 447-990-4 - - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 4-[2-(Cyclopropylmethoxy)ethyl]phenol 440-910-9 - 2017 View substance registered dossier
FINORGA - MOURENX avenue du lac 64150 MOURENX France France Active 4-[2-(Cyclopropylmethoxy)ethyl]phenol 440-910-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active 4-[2-(Cyclopropylmethoxy)ethyl]phenol 440-910-9 - - View substance registered dossier
Schering-Plough (Ireland) Company Avondale Co Wicklow Avondale Co. Wicklow Ireland Ireland Active 4-[4-[4-[(3R, 5R)[5-(2,4-difluorophenyl) tetrahydro-5-(1H-1,2,4-triazol-1-yl-methyl)-furan-3-yl]methyloxy]phenyl]-1-piperazinyl]phenyl-2-[(1S,2S)(1-ethyl-2-phenylmethoxypropyl)]-2,4-dihydro-3Htriazol-3-one 938-153-9 - 2014 View substance registered dossier
MSD International GmbH Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active 4-[4-[4-[(3R, 5R)[5-(2,4-difluorophenyl) tetrahydro-5-(1H-1,2,4-triazol-1-yl-methyl)-furan-3-yl]methyloxy]phenyl]-1-piperazinyl]phenyl-2-[(1S,2S)(1-ethyl-2-phenylmethoxypropyl)]-2,4-dihydro-3Htriazol-3-one 938-153-9 - 2015; 2017 View substance registered dossier
- - - - 4-[bis(2-tert-butyl-4-hydroxy-6-methylphenyl)methyl]phenyl 6-diazo-5-oxo-5,6-dihydronaphthalene-1-sulfonate 451-040-4 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-[difluoro(3,4,5-trifluorophenoxy)methyl]-2',3,5-trifluoro-4''-pentyl-1,1':4',1''-terphenyl 935-977-0 - 2019 View substance registered dossier
ICROM S.r.l Via delle arti, 33 20863 Concorezzo Italy Italy Active 4-acetilammino-N-((1-etil-2pirrolidinil)metil) -5 etilsulfonil-2-metossi benzamide 925-003-2 - - View substance registered dossier
- - - - 4-acetyloxy-5β,20-epoxy-1,2α,4,7β,10β,13α-hexahydroxy-9-oxotax-11-en-2-yl benzoate 418-680-6 - - View substance registered dossier
FARMAK, a.s. Na vlcinci 16/3 779 00 Olomouc Czech Republic Czech Republic Active 4-Amino-5-chloro-2,1,3-benzothiodiazole 457-490-8 - 2009; 2015 View substance registered dossier
- - - - 4-amino-5-ethyl-1-(2-methoxyethyl)-1H-Pyrazole-3-carboxamide 438-910-9 - - View substance registered dossier
Huntsman Textile Effects (Germany) GmbH Rehlinger Str. 1 D-86462 Langweid a.Lech Germany Germany Active 4-amino-6-((E)-(4-(4-(ethenylsulfonyl)butanoyl)amino)-diazenyl)-3-((E)-4- (ethenylsulfonyl)-diazenyl)-5-hydroxypolycarbocyclo, polysulfonate, polyphenyl, sodium salt 401-000-7 - 2010; 2013; 2014 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-amino-6-((E)-(4-(4-(ethenylsulfonyl)butanoyl)amino)-diazenyl)-3-((E)-4- (ethenylsulfonyl)-diazenyl)-5-hydroxypolycarbocyclo, polysulfonate, polyphenyl, sodium salt 401-000-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active 4-amino-6-((E)-(4-(4-(ethenylsulfonyl)butanoyl)amino)-diazenyl)-3-((E)-4- (ethenylsulfonyl)-diazenyl)-5-hydroxypolycarbocyclo, polysulfonate, polyphenyl, sodium salt 401-000-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Danish competent national authority. - - Active 4-amino-6-((E)-(4-(4-(ethenylsulfonyl)butanoyl)amino)-diazenyl)-3-((E)-4- (ethenylsulfonyl)-diazenyl)-5-hydroxypolycarbocyclo, polysulfonate, polyphenyl, sodium salt 401-000-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 4-amino-6-((E)-(4-(4-(ethenylsulfonyl)butanoyl)amino)-diazenyl)-3-((E)-4- (ethenylsulfonyl)-diazenyl)-5-hydroxypolycarbocyclo, polysulfonate, polyphenyl, sodium salt 401-000-7 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-bromo-2,3',4',5'-tetrafluoro-1,1'-biphenyl 936-926-5 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-Butoxy-2,3-difluor-4'-methyl-1,1'-biphenyl 938-422-0 - - View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa-Attiki Greece Greece Active 4-chloro-6-methoxypyrimidine 435-030-7 - 2014; 2015; 2020 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-chloromethyl-4''-ethyl-2'-fluoro-[1,1':4',1''-terphenyl] 936-119-8 - 2018 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-cis-ethyl-4'-trans-propyl-[1,1'-bicyclohexyl] 935-545-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-CPH 428-130-7 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-ethoxy-2,3-difluoro-4'-(trans-4-propylcyclohexyl)-1,1'-biphenyl 921-136-5 - - View substance registered dossier
Huntsman (Europe) BV - OR1 Everslaan 45 B-3078 Everberg Belgium Belgium Active 4-ethyl-1,3-dioxolan-2-one 403-780-4 - 2011 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-ethyl-1,3-dioxolan-2-one 403-780-4 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 4-ethyl-2-fluoro-4'-(2-(trans-4-propylcyclohexyl)ethyl)biphenyl 433-190-2 - - View substance registered dossier
- - - - 4-Fluoro-3-hydroxybenzoic acid 434-190-5 - - View substance registered dossier
Fareva La Vallée 928 avenue Lavoisier ZI de Blavozy 43700 Saint Germain Laprade Auvergne France France Active 4-Fluoro-3-hydroxybenzoic acid 434-190-5 - - View substance registered dossier
FujiFilm Manufacturing Europe BV Oudenstaart 1 5047 TK Tilburg Netherlands Netherlands Active 4-hexadecyl-1-phenylpyrazolidin-3-one 430-840-7 - 2011 View substance registered dossier
Honeywell Specialty Chemicals Seelze GmbH Wunstorfer Strasse 40 D-30926 Seelze Lower Saxony Germany Germany Cease Manufacture 4-hexadecyl-1-phenylpyrazolidin-3-one 430-840-7 - 2020 View substance registered dossier
Janssen Pharmaceutical Science Unlimited Company Little Island County NA Cork Ireland Ireland Active 4-Hydroxy-3,5-dimethylbenzonitrile 452-810-2 - 2018 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture 4-Hydroxy-3,5-dimethylbenzonitrile 452-810-2 - 2019 View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active 4-hydroxy-3-methyl-5-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]pentan-2-one 949-712-1 - - View substance registered dossier
DSM Nutritional Products GmbH - OR1 Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany Germany Active 4-hydroxybutan-2-one + 3-(hydroxymethyl)but-3-en-2-one 908-868-0 - 2020 View substance registered dossier
ORGANICA Feinchemie GmbH Wolfen Ortsteil Wolfen Kunstseidestraße 5 06766 Bitterfeld-Wolfen Germany Germany Active 4-hydroxybutane-1-sulfonic acid 928-903-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 4-hydroxyphenyl 4-(allyloxy)benzoate 433-210-1 - - View substance registered dossier
- - - - 4-hydroxyphenyl 4-(allyloxy)benzoate 433-210-1 - - View substance registered dossier
- - - - 4-hydroxystyrene, 4-tbutoxy styrene and styrene copolymer 433-660-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active 4-hydroxystyrene, 4-tbutoxy styrene and styrene copolymer 433-660-7 - - View substance registered dossier
MITSUBISHI GAS CHEMICAL EUROPE GMBH Immermannstr. 13 40210 Duesseldorf Germany Germany Active 4-Isobutylbenzaldehyde 464-400-0 - 2014 View substance registered dossier
MITSUBISHI GAS CHEMICAL EUROPE GMBH Immermannstr.13 40210 Duesseldorf Germany Germany Active 4-Isobutylbenzaldehyde 464-400-0 - 2014 View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active 4-Methoxy-5-(3-morpholin-4-yl-propoxy)-2-nitro-benzonitrile 936-067-6 - - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active 4-methoxybenzyl 3-chloromethyl-5-oxo-6-phenylacetamido-(2H)5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 403-040-0 - - View substance registered dossier
Bristol Myers Squibb Srl Via del Murillo., km 2, 8 004013 Sermoneta Lazio Italy Italy Active 4-methoxybenzyl 3-chloromethyl-5-oxo-6-phenylacetamido-(2H)5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 403-040-0 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority. - - Active 4-methoxybenzyl 3-chloromethyl-5-oxo-6-phenylacetamido-(2H)5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 403-040-0 - - View substance registered dossier
CBW Chemie GmbH Bitterfeld-Wolfen Kühlturmstrasse 06803 Bitterfeld-Wolfen / OT Greppin Germany Germany Active 4-Methoxycarbonyl-2-methylthiophen-3-yl-ammonium hydrochloride 929-732-7 - 2013 View substance registered dossier
AGC Pharma Chemicals Europe, S.L.U. Camí de la Pomereda, 13 08380 Malgrat de Mar (Barcelona) Spain Spain Active 4-Methyl-2-propylbenzimidazole-6-carboxylic acid 424-450-6 - - View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active 4-Methyl-2-propylbenzimidazole-6-carboxylic acid 424-450-6 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Cease Manufacture 4-Methyl-2-propylbenzimidazole-6-carboxylic acid 424-450-6 - 2019 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture 4-Methyl-2-propylbenzimidazole-6-carboxylic acid 424-450-6 - 2015 View substance registered dossier

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