Registered substances
Registered substances
In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).
ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.
As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).
In the portal results table are presented:
- Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
- Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
- Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
- Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
- Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
- Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
- Link to the full factsheet.
A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.
- The REACH Registered substance portal was updated on 9th November 2020; the REACH registered factsheets were further updated on 21st December 2020. Details of the improvements can be found at Dissemination Platform Updates. Reprocessing the entire dataset is ongoing since 21 December 2020. ECHA is making all possible efforts to make the improvements and additional data visible with the shortest delay.
- The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
Further information
- Registered substances information
- How to determine what will be published (Data Submission Manual 15)
- Understanding REACH Regulation
- Q&A on registered substances
- What is an Infocard? [PDF]
- What is a Registered substance Factsheet? [PDF]
- eChemPortal
- REACH study results download
- REACH Regulation
- ECHA Legal notice
Last updated 02 March 2021. Database contains 23184 unique substances and contains information from 93505 dossiers.
Registrant/Supplier | Address | Country | Registration Status | Name | EC / List no. | CAS no. | Last update year | Details |
---|---|---|---|---|---|---|---|---|
F2 Chemicals Ltd | Lea Lane Lea Town PR4 0RZ Preston Lancashire United Kingdom | United Kingdom | No longer Valid | (E)-1,1,1,2,3,4,5,5,5-Nonafluoro-4-(trifluoromethyl)pent-2-ene | 807-113-1 | 3709-71-5 | 2021 | View substance registered dossier |
Fermion Oy | Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland | Finland | Active | (E)-2-(2-(4-dibenzo[b,f][1,4]thiazepin-11-yl)piperazin- 1-yl)ethoxy)ethanol hydrochloride | 696-107-0 | 930086-71-8 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (E)-3,7-dimethyl-2,6-octadienylhexadecanoate | 421-370-3 | 3681-73-0 | - | View substance registered dossier |
BASF Schwarzheide GmbH | Schipkauer Str. 1 01987 Schwarzheide Brandenburg Germany | Germany | Cease Manufacture | (E)-3-(2-chlorophenyl)-2-(4-fluorophenyl)propenal | 410-980-5 | 112704-51-5 | 2018 | View substance registered dossier |
- | - | - | - | (E)-3-(3-Pent-1-yloxiran-2-yl)prop-2-enal | 443-070-1 | 188590-62-7 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | (E)-3-(4-(4-fluorophenyl)-5-methoxymethyl-2,6-bis(1-methoxymethyl)pyridin-3-yl)prop-2-enal | 426-330-9 | 177964-68-0 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. | - | - | Active | (E)-3-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol | 428-010-4 | 82413-20-5 | - | View substance registered dossier |
Sterling Pharma Solutions Ltd | Dudley NE23 7QG Cramlington Northumberland United Kingdom | United Kingdom | No longer Valid | (E)-3-[6-(p-toluoyl)-2-pyridyl]acrylic acid | 302-128-5 | 94094-27-6 | 2021 | View substance registered dossier |
- | - | - | - | (E)-3-methyl-5-cyclopentadecen-1-one | 429-900-5 | 82356-51-2 | - | View substance registered dossier |
Symrise AG | Mühlenfeldstraße 1 37603 Holzminden Germany | Germany | Active | (E)-4-(3a,4,5,6,7,7a-hexahydro-1H-4,7-methanoinden-5-yl)-3-methylbut-3-en-2-ol; (E)-4-(3a,4,5,6,7,7a-hexahydro-3H-4,7-methanoinden-5-yl)-3-methylbut-3-en-2-ol; 1-(1,3a,4,6,7,7a-hexahydro-4,7-methanoinden-5-ylidene)pentan-3-ol; 1-(3,3a,4,6,7,7a-hexahydro-4,7-methanoinden-5-ylidene)pentan-3-ol; 4-(3,3a,4,6,7,7a-hexahydro-4,7-methanoinden-5-ylidene)-3-methylbutan-2-ol; reaction mass of: 4-(1,3a,4,6,7,7a-hexahydro-4,7-methanoinden-5-ylidene)-3-methylbutan-2-ol | 444-430-0 | - | 2011 | View substance registered dossier |
Boehringer Ingelheim Pharma GmbH & Co. KG | Binger Strasse 173 55216 Ingelheim am Rhein Germany | Germany | Active | (E)-4-Dimethylamino-but-2-enoic acid [4-(3-chloro-4-fluoro-phenyl-amino)-7-((S)-(tetrahydrofuran-3-yl)oxy)-quinazoline-6-yl]-amide | 923-981-5 | - | 2015 | View substance registered dossier |
Solvay Fluor GmbH | Hans-Boeckler-Allee 20 30173 HANNOVER Germany | Germany | Active | (E)-4-Ethoxy-1,1,1-trifluoro-3-buten-2-one (stabilized with BHT) | 475-900-3 | - | 2010; 2014; 2019 | View substance registered dossier |
Bayer AG | Kaiser-Wilhelm-Allee 51373 Leverkusen Germany | Germany | Active | (E)-5-benzyl-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-N-nitro-1,3,5-triazinan-2-imine | 606-753-7 | 213967-55-6 | 2010 | View substance registered dossier |
Novartis International Pharmaceutical ltd., Branch Ireland | Ringaskiddy IE Ringaskiddy Cork Ireland | - | - | (E)-N- (3-Chloroallyl)-n-Methyl-N-9Naphtalin-1-YL-methyl-amine | 449-170-1 | - | - | View substance registered dossier |
- | - | - | - | (E)-N- (3-Chloroallyl)-n-Methyl-N-9Naphtalin-1-YL-methyl-amine | 449-170-1 | - | - | View substance registered dossier |
FINORGA SAS | 497 route de Givors 38670 CHASSE SUR RHONE France | France | Active | (E)-N-((dialkylamino)alkylene)-3,5-bis(polyfluoroalkyl)benzamide | - | - | 2016 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. | - | - | Active | (E)-N-(pentan-2-ylidene)hydroxylamine | 484-470-6 | 623-40-5 | - | View substance registered dossier |
DSM Nutritional Products France SAS | 1 boulevard d'Alsace F-68128 Village-Neuf France | France | Active | (E,E)-3,7,11-trimethyldodeca-1,4,6,10-tetraen-3-ol | 423-240-1 | 125474-34-2 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (E,Z)-4-chlorophenyl(cyclopropyl)ketone O-(4-nitrophenylmethyl)oxime | 406-100-4 | 94097-88-8 | - | View substance registered dossier |
PCAS | 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France | France | Active | (E-E )-3,3'-(1,4-phenylenedimethylidene)bis(2-oxobornane-10-sulfonic acid) | 410-960-6 | 92761-26-7 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (ethyl-3-oxobutanoato-O'1,O'3)(2-dimethylaminoethanolato)(1-methoxypropan-2-olato)aluminium(III), dimerised | 402-370-2 | 149057-70-5 | - | View substance registered dossier |
Nouryon Surface Chemistry AB | Stenunge Allé 3 - S-44485 Stenungsund - Sweden | Sweden | Active | (hydroxyethyl)urea | 215-304-0 | 1320-51-0 | 2013 | View substance registered dossier |
- | - | - | - | (imidazol-5-yl)ethyl-3-aminopropionamide dihydrochloride | 415-470-6 | - | - | View substance registered dossier |
Wacker Chemie AG | Hanns-Seidel-Platz 4 81737 Muenchen Germany | Germany | Active | (Isocyanatomethyl)(dimethoxy)methylsilane | 453-230-2 | - | 2011 | View substance registered dossier |
CARBOGEN AMCIS B.V. | Nieuweweg 2a 3901 BE Veenendaal Netherlands | Netherlands | Active | (methoxymethyl)triphenylphosphonium chloride | 223-664-5 | 4009-98-7 | - | View substance registered dossier |
AlzChem Trostberg GmbH | Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany | Germany | Active | (N-phenylcarbamimidoyl)ammonium carbonate hydrate | 485-350-6 | - | 2009; 2019 | View substance registered dossier |
[Confidential] | - | - | - | (N-phenylcarbamimidoyl)ammonium carbonate hydrate | 485-350-6 | - | - | View substance registered dossier |
Siegfried St. Vulbas SAS | 530, allée de la Luye 01150 SAINT VULBAS France | France | Active | (p-chlorophenyl)metaboric acid | 216-845-5 | 1679-18-1 | - | View substance registered dossier |
ICL Europe Coöperatief U.A. (OR1) | Koningin Wilhelminaplein 30 Prinsenhof 1062 KR Amsterdam Netherlands | Netherlands | Active | (pentabromophenyl)methyl acrylate | 261-767-7 | 59447-55-1 | - | View substance registered dossier |
Boehringer Ingelheim Pharma GmbH & Co. KG | Binger Strasse 173 55216 Ingelheim am Rhein Germany | - | - | (Phenylethyl)-propylpyrandion | 448-120-6 | - | - | View substance registered dossier |
MITSUBIHI PENCIL FRANCE S.A. | 32 avenue Pierre Grenier 92517 Boulogne-Billancourt Cedex France | France | Active | (phenylmethylene)di-2,1-phenylene ditetradecanoate | 941-526-9 | - | - | View substance registered dossier |
PIERRE FABRE MEDICAMENT | 45 place Abel Gance 92654 Boulogne France | France | Active | (pyridin-3-yl)methanol hydrofluoride | 700-352-1 | 62756-44-9 | - | View substance registered dossier |
BASF SE | Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany | Germany | Active | (R)-(-)-1-methoxy-2-propylamine | 620-037-1 | 99636-38-1 | 2010 | View substance registered dossier |
Krka, d. d., Novo mesto | Smarjeska cesta 6 SI-8501 Novo mesto Slovenia | Slovenia | Active | (R)-1-((4-chlorophenyl)(phenyl)methyl)piperazine (3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate | 694-988-6 | 1235588-99-4 | - | View substance registered dossier |
Siegfried PharmaChemikalien Minden GmbH | Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany | Germany | Active | (R)-1-hydroxy-1-phenylacetone | 217-285-4 | 1798-60-3 | 2013 | View substance registered dossier |
NuFarm Limited | Wyke Lane BD12 9EJ Wyke West Yorkshire United Kingdom | United Kingdom | No longer Valid | (R)-2-(4-hydroxyphenoxy)propanoic acid | 407-960-3 | 94050-90-5 | 2021 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (R)-2-acetamido-3-naphthyl-2-yl-propionic acid | 440-450-9 | - | - | View substance registered dossier |
- | - | - | - | (R)-2-bromo-3-methylbutyric acid diisopropylamine salt | 448-650-8 | 169320-29-0 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (R)-2-tert-butoxycarbonylamino-3-(4-chlorophenyl)propionic acid | 438-070-3 | - | - | View substance registered dossier |
- | - | - | - | (R)-2-tert-butoxycarbonylamino-3-(pyridin-3-yl)propionic acid | 441-200-1 | - | - | View substance registered dossier |
Amino Chemicals Ltd | Industrial Estate, A61 MRS3000 Marsa Malta | Malta | Active | (R)-2-{[(3-methyl-4-nitropyridine-2-yl)methyl]sulfinyl}-1H-benzimidazole | 700-683-1 | 853950-77-3 | - | View substance registered dossier |
Pfizer Ireland Pharmaceuticals | n/a P43 X3336 Ringaskiddy Cork Ireland | Ireland | Active | (R)-3-(2-benzyloxy)-5-bromophenyl)-N,N-diisopropyl-3-phenylpropan-1-amine | 700-662-7 | 950773-38-3 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (R)-3-[(1-methylpyrrolidin-2-yl)methyl]-5-[2-(phenylsulfonyl)ethenyl]-1H-indole | 430-560-5 | 180637-89-2 | - | View substance registered dossier |
COVANCE CLINICAL DEVELOPMENT SA 171 | Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain | Spain | Cease Manufacture | (R)-3-chloropropane-1,2-diol | 435-560-9 | 57090-45-6 | 2012 | View substance registered dossier |
Lundbeck Pharmaceuticals Italy S.p.A | via quarta strada 2 35129 padova Italy | Italy | Active | (R)-4-(4-dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemi (2R, 3R)-2,3-bis((4-methylbenzoyl)oxy)succinoate | 949-784-4 | - | - | View substance registered dossier |
- | - | - | - | (R)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide | 419-800-1 | - | - | View substance registered dossier |
TAKASAGO TICSA-Producer/Importer | Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain | Spain | Active | (R)-6-(isopropyl)-3-methylcyclohex-2-en-1-one | 224-957-0 | 4573-50-6 | - | View substance registered dossier |
FRESENIUS KABI iPSUM s.r.l. | Via Roma, 108 20060 Cassina de' Pecchi (MI) Italy | Italy | Active | (R)-[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetic acid | 264-133-8 | 63422-71-9 | - | View substance registered dossier |
RHODIA OPERATIONS | 52 rue de la Haie Coq 93300 AUBERVILLIERS France | France | Active | (R)-Methyl-2-fluoropropanoate | 478-990-2 | - | 2010 | View substance registered dossier |
Minakem Dunkerque Production | 224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France | France | Active | (R)-N-[(1E)-1-(5-bromo-2-fluorophenyl)ethylidene]-2-methylpropane-2-sulfinamide | 810-396-4 | 1194044-26-2 | 2017 | View substance registered dossier |
Clarochem Ireland Ltd | damastown mulhuddart dn 15 dublin Ireland | Ireland | Active | (R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate | 418-570-8 | 25383-07-7 | 2016 | View substance registered dossier |
- | - | - | - | (R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate | 418-570-8 | 25383-07-7 | - | View substance registered dossier |
Excella GmbH & Co. KG | Nuernberger Str. 12 90537 Feucht Germany | Germany | Active | (R*,S*)-(±)-α-[4-[2-(dimethylamino)ethoxy]phenyl]-β-ethyl-α-phenylphenethyl alcohol | 278-718-0 | 77542-06-4 | - | View substance registered dossier |
Pfizer Ireland Pharmaceuticals | n/a P43 X3336 Ringaskiddy Cork Ireland | Ireland | Active | (R,S)-1-[2-amino-1(4-methoxyphenyl)ethyl]cyclohexanol acetate | 445-750-3 | 839705-03-2 | 2013 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. | - | - | Active | (R,S)-2-amino-3,3-dimethylbutane amide | 447-860-7 | 144177-62-8 | - | View substance registered dossier |
Vishay BCcomponents B.V. | Ceintuurbaan 15 8022 AW Zwolle Netherlands | Netherlands | Active | (R,S)-2-butyloctanedioic acid | 431-210-4 | 50905-10-7 | - | View substance registered dossier |
PCAS | 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France | France | Active | (R,S)-N-acetyl-(3,4-dimethoxyphenyl)-alanine, monohydrate | 608-083-0 | 27313-65-1 | - | View substance registered dossier |
Plixxent B.V. | Korte Groningerweg 1A 9607 Foxhol Netherlands | Netherlands | Active | (Reaction product of 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol, 2-(2-hydroxyethylamino)ethanol and formaldehyde), propoxylated | 926-000-9 | - | 2013; 2016; 2017; 2018; 2021 | View substance registered dossier |
Syngenta Ltd | Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom | United Kingdom | Cease Manufacture | (RS)-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)hexan-2-ol | 413-050-7 | 79983-71-4 | 2013 | View substance registered dossier |
Bayer Agriculture bvba | Scheldelaan 460 B-2040 Antwerp Belgium | Belgium | Cease Manufacture | (RS)-3-dichloroacetyl-5-(2-furanyl)-2,2-dimethyloxazolidine | 434-800-1 | - | 2020 | View substance registered dossier |
- | - | - | - | (S) 4-hydroxy-3-methyl-2-prop-2-ynylcyclopent-2-en-1-one | 462-540-7 | 77087-34-4 | - | View substance registered dossier |
BASF SE | Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany | Germany | Active | (S)-(+)-1-methoxy-2-propylamine | 700-220-3 | 99636-32-5 | 2010 | View substance registered dossier |
Janssen Pharmaceutica N.V. | Turnhoutseweg 30 2340 Beerse Belgium | Belgium | Cease Manufacture | (S)-(+)-2-(2-Chlorophenyl)-2-hydroxyacetic acid | 700-307-6 | 52950-19-3 | 2019 | View substance registered dossier |
Carbogen Amcis Ltd | 303 Clayton Lane M11 4SX Manchester Greater Manchester United Kingdom | United Kingdom | Active | (S)-(-)-tetrahydro-2-furoic acid | 433-770-5 | - | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (S)-(-)-tetrahydro-2-furoic acid | 433-770-5 | - | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Danish competent national authority. | - | - | Active | (S)-.alpha.-cyano-3-phenoxybenzyl (Z)-(1R)-cis-3-(2-chloro-3,3,3-trifluoropropenyl)-2,2-dimethylcyclopropanecarboxylate | 435-840-0 | 76703-62-3 | - | View substance registered dossier |
Reuter Chemische Apparatebau e.K. | Engesserstrasse 4b 79108 Freiburg Germany | Germany | Active | (S)-1,1'-Binaphthalene-2,2'-diol | 606-050-5 | 18531-99-2 | 2011; 2013 | View substance registered dossier |
DSM Nutritional Products GmbH | Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany | Germany | Cease Manufacture | (S)-1,1-diphenyl-1,2-propanediol | 443-220-6 | 46755-94-6 | 2019 | View substance registered dossier |
UnaveraChemLab | Am Ländbach 20 82481 Mittenwald Germany | Germany | Active | (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol | 700-699-9 | 877397-65-4 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. | - | - | Active | (S)-1-[2-tert-butoxycarbonyl-3-(2-methoxyethoxy)propyl]-1-cyclopentanecarboxylic acid, cyclohexylamine salt | 425-510-4 | 167944-94-7 | - | View substance registered dossier |
Covance Clinical Development SA 169 | Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain | Spain | Active | (S)-1-chloro-2,3-epoxypropane | 482-080-0 | 67843-74-7 | 2011 | View substance registered dossier |
DSM Pharma Chemicals Venlo B.V. | Grubbenvorsterweg 8 Postbox 81 5900 AB Venlo Netherlands | Netherlands | Active | (S)-2,3-dihydro-1H-indole-2-carboxylic acid | 410-860-2 | 79815-20-6 | - | View substance registered dossier |
Boehringer Ingelheim Pharma GmbH & Co. KG | Binger Strasse 173 55216 Ingelheim am Rhein Germany | Germany | Active | (S)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole Tartrat Trihydrate | 928-472-1 | - | - | View substance registered dossier |
Cambrex Karlskoga AB | Bjorkborns Industriomrade 69185 Karlskoga Sweden | Sweden | Cease Manufacture | (S)-2-(1-aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one hydrochloride | 942-180-1 | - | 2017 | View substance registered dossier |
Flamma S.p.a. | via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy | Italy | Active | (S)-2-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid | 951-381-3 | - | - | View substance registered dossier |
Sterling Pharma Solutions Ltd | Dudley NE23 7QG Cramlington Northumberland United Kingdom | United Kingdom | No longer Valid | (S)-2-(5-Oxo-3-propyl-1,2-dihydropyrrol-1-yl) butyramide | 824-341-7 | 357338-13-7 | 2021 | View substance registered dossier |
Flamma S.p.a. | via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy | Italy | Active | (S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid | 439-640-4 | - | 2019; 2020 | View substance registered dossier |
QUIMICA SINTETICA, S.A. | C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain | Spain | Active | (S)-2-amino-1,1-diphenyl 1-propanol | 622-109-8 | 78603-91-5 | - | View substance registered dossier |
Boehringer Ingelheim Pharma GmbH & Co. KG | Binger Strasse 173 55216 Ingelheim am Rhein Germany | Germany | Cease Manufacture | (S)-2-Amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole | 600-593-1 | 104632-26-0 | 2019 | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Active | (S)-2-chloro-1-(3,4-difluorophenyl)ethan-1-ol | 819-945-2 | 1006376-60-8 | - | View substance registered dossier |
- | - | - | - | (S)-2-chloropropionic acid | 411-150-5 | 29617-66-1 | - | View substance registered dossier |
Esteve Quimica, S.A. | Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain | Spain | Cease Manufacture | (S)-3-benzyloxycarbonyl-1,2,3,4-tetrahydro-isoquinolinium 4-methylbenzenesulfonate | 406-960-0 | 77497-97-3 | 2017 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (S)-3-hydroxy-γ-butyrolactone | 434-990-4 | 7331-52-4 | - | View substance registered dossier |
Boehringer Ingelheim Pharma GmbH & Co. KG | Binger Strasse 173 55216 Ingelheim am Rhein Germany | Germany | Active | (S)-3-Methyl-1-(2-piperidine-1-phenyl)butylamine compound with N-Acetyl-L-glutamic acid | 606-883-4 | 219921-94-5 | - | View substance registered dossier |
Boehringer Ingelheim Pharma GmbH & Co. KG | Binger Strasse 173 55216 Ingelheim am Rhein Germany | Germany | Active | (S)-3-Methyl-1-(2-piperidinophenyl)-1-butylamine | 604-603-5 | 147769-93-5 | - | View substance registered dossier |
Amri Italy S.r.l. | VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy | Italy | Active | (S)-3-methyl-2-(2-oxotetrahydropyrimidine-1-yl)butyric acid | 430-900-2 | 192725-50-1 | - | View substance registered dossier |
Fermion Oy | Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland | Finland | Active | (S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile | 941-762-2 | 1297537-41-7 | - | View substance registered dossier |
H. Lundbeck A/S | Ottiliavej 7-9 2500 Copenhagen Denmark | - | - | (S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile | 430-770-7 | 128173-52-4 | - | View substance registered dossier |
- | - | - | - | (S)-4-amino-5-[(2-(1H-imidazol-4-yl)ethyl)amino]-5-oxopentanoic acid | 421-900-3 | - | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority. | - | - | Active | (S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione | 444-280-6 | 7689-03-4 | - | View substance registered dossier |
bracco imaging | Via Folli 50 20134 milan Italy | Italy | Active | (S)-5-[2-(acetyloxy)propanamido]-2,4,6-triiodo-1,3-di(chloroformyl)benzene | 410-940-7 | - | - | View substance registered dossier |
Fermion Oy | Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland | Finland | Active | (S)-5-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-3-carboxamide | 941-760-1 | 1297537-33-7 | - | View substance registered dossier |
Patheon Austria GmbH & Co KG | St. Peterstrasse 25 A-4020 Linz Austria | Austria | Active | (S)-5-tert-butoxy-3-(tert-butyldimethylsilyloxy)-5-oxopentylboronic acid (+)-pinanediol ester | 811-219-3 | 1681053-95-1 | - | View substance registered dossier |
- | - | - | - | (S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle | 439-220-0 | - | - | View substance registered dossier |
AstraZeneca | B313:5 AZ GlobalSHE- Chem.Reg. SE-15185 Södertälje Sweden | Sweden | Cease Manufacture | (S)-azetidine-2-carboxylic acid 4-cyanobenzylamide hydrochloride | 433-010-2 | - | 2012 | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Active | (S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate | 445-820-3 | - | - | View substance registered dossier |
Cambrex Karlskoga AB | Bjorkborns Industriomrade 69185 Karlskoga Sweden | Sweden | Cease Manufacture | (S)-tert-butyl(1-((3-fluoro-2-(phenylcarbamoyl)phenyl)amino)-1-oxobutan-2 yl)carbamate | 942-159-7 | - | 2017 | View substance registered dossier |
Patheon Austria GmbH & Co KG | St. Peterstrasse 25 A-4020 Linz Austria | Austria | Active | (S)-tert.-Butyl-[2-(aminoethoxy)-[1,2]oxaborolan-4-yl]acetate | 942-682-0 | - | - | View substance registered dossier |
DOW CHEMICAL COMPANY LTD | Diamond House, Lotus Park Kingsbury Crescent Middx UB7 0DQ Staines Middx United Kingdom | United Kingdom | Cease Manufacture | (S)-α-hydroxy-3-phenoxy-benzeneacetonitrile | 441-070-6 | 61826-76-4 | 2013 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. | - | - | Active | (S,S)-1,1,1,2,2,3,4,5,5,5-decafluoropentane; reaction mass of: (R,R)-1,1,1,2,2,3,4,5,5,5-decafluoropentane | 420-640-8 | 138495-42-8 | - | View substance registered dossier |
F.I.S. Fabbrica Italiana Sintetici S.p.a. | Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy | Italy | Active | (S,S)-trans-4-(acetylamino)-5,6-dihydro-6-methyl-7,7-dioxo-4H-thieno[2,3-b]thiopyran-2-sulfonamide | 415-030-3 | 120298-38-6 | - | View substance registered dossier |
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