Registered substances
Registered substances
In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).
ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.
As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).
In the portal results table are presented:
- Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
- Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
- Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
- Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
- Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
- Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
- Link to the full factsheet.
A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.
Please note:
- The REACH Registered substance portal was updated on 9th November 2020; the REACH registered factsheets were further updated on 21st December 2020. Details of the improvements can be found at Dissemination Platform Updates. Reprocessing the entire dataset is ongoing since 21 December 2020. ECHA is making all possible efforts to make the improvements and additional data visible with the shortest delay.
- The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
Further information
- Registered substances information
- How to determine what will be published (Data Submission Manual 15)
- Understanding REACH Regulation
- Q&A on registered substances
- What is an Infocard? [PDF]
- What is a Registered substance Factsheet? [PDF]
- eChemPortal
- REACH study results download
- REACH Regulation
- ECHA Legal notice
Last updated 01 March 2021. Database contains 23117 unique substances and contains information from 96017 dossiers.
| Registrant/Supplier | Address | Country | Registration Status | Name | EC / List no. | CAS no. | Last update year | Details |
|---|---|---|---|---|---|---|---|---|
| CU Chemie Uetikon GmbH | Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany | Germany | Active | 5,6-dihydroxy-2,3-dihydro-1H-indolium bromide | 421-170-6 | 138937-28-7 | - | View substance registered dossier |
| NOVEAL | 16 rue Maurice Berteaux 95500 LE THILLAY France | France | Active | 5,6-dihydroxyindole | 412-130-9 | 3131-52-0 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | 5,7-dichloro-4-hydroxyquinoline | 427-420-0 | 21873-52-9 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. | - | - | Active | 5,7-dichloro-4-hydroxyquinoline | 427-420-0 | 21873-52-9 | - | View substance registered dossier |
| RHODIA OPERATIONS | 52 rue de la Haie Coq 93300 AUBERVILLIERS France | France | Cease Manufacture | 5,7-dichloro-4-hydroxyquinoline | 427-420-0 | 21873-52-9 | 2019 | View substance registered dossier |
| RHODIA OPERATIONS | 52 rue de la Haie Coq 93300 AUBERVILLIERS France | France | Cease Manufacture | 5,7-dichloro-4-hydroxyquinoline-3-carboxylic acid | 431-250-2 | 171850-30-9 | 2019 | View substance registered dossier |
| - | - | - | - | 5-((6-(ethyl(phenyl)amino)-1,3,5-triazin-2-yl)amino)-3-((E)-(5-((propanoyl)amino)- phenyl)diazenyl)-4-hydroxy polycarbocyclyl, polysulfonate, polyhalogeno, sodium salt | 415-950-5 | - | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidine)-3- fluoro-2-hydroxymethyltetrahydrofuran | 415-360-8 | 41107-56-6 | - | View substance registered dossier |
| - | - | - | - | 5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidine)-3- fluoro-2-hydroxymethyltetrahydrofuran | 415-360-8 | 41107-56-6 | - | View substance registered dossier |
| DyStar Colours Distribution GmbH | Am Prime-Parc 12 65479 Raunheim Germany | Germany | Active | 5-(2-amino-5-cyano-6-[2-(2-hydroxyethoxy)ethylamino]-4-methylpyridin-3-ylazo)-3-methyl-2,4-dicarbonitrilethiophene | 410-530-8 | - | 2010 | View substance registered dossier |
| - | - | - | - | 5-(2-bromophenyl)-2-tert-butyl-2H-tetrazole | 420-820-6 | - | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. | - | - | Active | 5-(2-chloroacetyl)-8-phenylmethoxy-1H-quinolin-2-one | 453-270-0 | 63404-86-4 | - | View substance registered dossier |
| - | - | - | - | 5-(2-chloroacetyl)-8-phenylmethoxy-1H-quinolin-2-one | 453-270-0 | 63404-86-4 | - | View substance registered dossier |
| DyStar Colours Distribution GmbH | Am Prime-Parc 12 65479 Raunheim Germany | Germany | Active | 5-(2-cyano-4-nitrophenylazo)-6-(2-(2-hydroxyethoxy)ethylamino)-4-methyl-2-phenylaminonicotinonitrile; reaction mass of: 5-(2-cyano-4-nitrophenylazo)-2-(2-(2-hydroxyethoxy)ethylamino)-4-methyl-6-phenylaminonicotinonitrile | 429-760-5 | - | 2011; 2020 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 5-(3-butyryl-2,4,6-trimethylphenyl)-2-[1-(ethoxyimino)propyl]-3-hydroxycyclohex-2-en-1-one | 414-790-3 | 138164-12-2 | - | View substance registered dossier |
| Syngenta Ltd | Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom | United Kingdom | Cease Manufacture | 5-(3-butyryl-2,4,6-trimethylphenyl)-2-[1-(ethoxyimino)propyl]-3-hydroxycyclohex-2-en-1-one | 414-790-3 | 138164-12-2 | 2013 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 5-(4-(N-(2-acetoxyethyl)-N-ethylamino)-2-methylphenylazo)-4-cyano-3-methylisothiazole | 405-480-9 | 110260-50-9 | - | View substance registered dossier |
| Fujifilm Europe GmbH (OR2) | Heesenstr. 31 40549 Düsseldorf NRW Germany | Germany | Active | 5-(4-[4-[4-(3,5-dicarboxy-phenyl-azo)phenylamino]-6-morpholin-4-yl-1,3,5-triazin-2-ylamino]phenylazo)isophthalic acid, mixed monosodium and diammonium salt | 414-410-6 | - | 2010 | View substance registered dossier |
| Fujifilim Imaging Colorants OR | Patricia Way Pysons Road Industrial Estate CT10 2LE Broadstairs Kent United Kingdom | United Kingdom | Active | 5-(4-[4-[4-(3,5-dicarboxy-phenyl-azo)phenylamino]-6-morpholin-4-yl-1,3,5-triazin-2-ylamino]phenylazo)isophthalic acid, mixed monosodium and diammonium salt | 414-410-6 | - | - | View substance registered dossier |
| DyStar Colours Distribution GmbH | Am Prime-Parc 12 65479 Raunheim Germany | Germany | Active | 5-(4-chloro-2-nitro-phenylazo)-1,2-dihydro-6-hydroxy-1,4-dimethyl-2-oxo-pyridine-3-carbonitrile | 425-310-7 | 77889-90-8 | - | View substance registered dossier |
| PMC ISOCHEM | 32 rue Lavoisier 91710 VERT LE PETIT France | France | Active | 5-(difluoromethoxy)-1,3-dihydrobenzimidazole-2-thione | 417-780-7 | - | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority. | - | - | Active | 5-(difluoromethoxy)-1,3-dihydrobenzimidazole-2-thione | 417-780-7 | - | - | View substance registered dossier |
| Takeda GmbH | Byk-Gulden-Strasse 2 78467 Konstanz Baden-Württemberg Germany | Germany | Active | 5-(difluoromethoxy)-1,3-dihydrobenzimidazole-2-thione | 417-780-7 | - | - | View substance registered dossier |
| - | - | - | - | 5-(trans-4-propylcyclohexyl)-2-trans-(3,4,5-trifluorophenyl)-1,3-dioxane | 442-740-0 | 181943-57-7 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. | - | - | Active | 5-[5-amino-4-substituted-phenylazo-phenylanilino]-chloro-heteromonocyclylamino-3- (naphthalen-2-ylazo)-4-hydroxynaphthalene-polysulfonic acid, sodium salt | 455-860-3 | - | - | View substance registered dossier |
| Huntsman Textile Effects (Germany) GmbH | Rehlinger Str. 1 D-86462 Langweid a.Lech Germany | Germany | Active | 5-[[4-chloro-6-[[2-[[4-fluoro-6-[[5-hydroxy-6-[(4-methoxy-2-sulfophenyl)azo]-7-sulfo-2-naphthalenyl]amino]-1,3,5-triazin-2-yl]amino]-1-methylethyl]amino]-1,3,5-triazin-2-yl]amino]-3-[[4-(ethenylsulfonyl)phenyl]azo]-4-hydroxy-naphtalene-2,7-disulfonic acid, sodium salt | 418-380-5 | 168113-78-8 | 2010 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. | - | - | Active | 5-[[4-chloro-6-[[2-[[4-fluoro-6-[[5-hydroxy-6-[(4-methoxy-2-sulfophenyl)azo]-7-sulfo-2-naphthalenyl]amino]-1,3,5-triazin-2-yl]amino]-1-methylethyl]amino]-1,3,5-triazin-2-yl]amino]-3-[[4-(ethenylsulfonyl)phenyl]azo]-4-hydroxy-naphtalene-2,7-disulfonic acid, sodium salt | 418-380-5 | 168113-78-8 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 5-acetoxy-2-(R,S)butyryloxymethyl-1,3-oxathiolane | 433-530-1 | 143446-73-5 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | 5-acetoxy-2-(R,S)butyryloxymethyl-1,3-oxathiolane | 433-530-1 | 143446-73-5 | - | View substance registered dossier |
| Patheon Austria GmbH & Co KG | St. Peterstrasse 25 A-4020 Linz Austria | Austria | Active | 5-acetoxy-2-(R,S)butyryloxymethyl-1,3-oxathiolane | 433-530-1 | 143446-73-5 | - | View substance registered dossier |
| Boehringer Ingelheim Pharma GmbH & Co. KG | Binger Strasse 173 55216 Ingelheim am Rhein Germany | Germany | Cease Manufacture | 5-acetyl-3-amino-10,11-dihydro-5H-dibenz[b,f]azepine-hydrochloride | 410-490-1 | 138451-65-7 | 2015 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Norwegian competent national authority. | - | - | Active | 5-acetylamino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenecarboxamide | 445-830-8 | 31127-80-7 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. | - | - | Active | 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-1H-pyrazole-3-carbonitrile | 421-240-6 | 120068-79-3 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. | - | - | Active | 5-amino-2,4,6-triiodo-1,3-benzenedicarbonyldichloride | 417-220-1 | 37441-29-5 | - | View substance registered dossier |
| Borregaard AS | Hjalmar Wessels vei 6 1701 Sarpsborg Norway | Norway | Active | 5-amino-2,4,6-triiodo-1,3-benzenedicarbonyldichloride | 417-220-1 | 37441-29-5 | - | View substance registered dossier |
| - | - | - | - | 5-amino-4,6-dichloro-2-methylpyrimidine | 419-110-9 | - | - | View substance registered dossier |
| Synthesia, a.s. | Semtín103 53002 Pardubice Czech Republic | Czech Republic | Active | 5-amino-6-[4-(4-amino-2-hydroxyphenylazo)phenylazo]-3-(2,5-dichlorphenylazo)-4-hydroxy-2,7-naphthalenedisulfonic acid-, disodium salt | 459-310-3 | - | - | View substance registered dossier |
| BASF Grenzach GmbH | Köchlinstr. 1 79639 Grenzach-Wyhlen Germany | Germany | Active | 5-amino-6-methyl-1,3-dihydrobenzoimidazol-2-one | 428-410-9 | 67014-36-2 | - | View substance registered dossier |
| Takeda Austria GmbH | St. Peter-Str. 25 4020 Linz Austria | Austria | Active | 5-Amino-N,N'-bis(2,3-dihydroxypropyl)-1,3-phthaldiamidehydrochloride | 421-690-3 | - | - | View substance registered dossier |
| Borregaard AS | Hjalmar Wessels vei 6 1701 Sarpsborg Norway | Norway | Active | 5-Amino-N,N'-bis(2,3-dihydroxypropyl)-1,3-phthaldiamidehydrochloride | 421-690-3 | - | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 5-amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide | 428-150-6 | 113171-13-4 | - | View substance registered dossier |
| Huntsman Textile Effects (Germany) GmbH | Rehlinger Str. 1 D-86462 Langweid a.Lech Germany | Germany | Cease Manufacture | 5-bromo-8-naphtholactam | 413-480-5 | 24856-00-6 | 2014 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | 5-CHLORCARBONYL-5H-DIBENZ(B,F)AZEPIN | 412-100-5 | - | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 5-chloro-1,3-dihydro-2H-indol-2-one | 412-200-9 | 17630-75-0 | - | View substance registered dossier |
| Cytec Industries BV OR for UK | Burgemeester van Lierplein 75 3134 ZB Vlaardingen Netherlands | Netherlands | Cease Manufacture | 5-chloro-2,3-difluoropyridine | 410-090-7 | 89402-43-7 | 2019 | View substance registered dossier |
| Syngenta Ltd | Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom | United Kingdom | Cease Manufacture | 5-chloro-2,3-difluoropyridine | 410-090-7 | 89402-43-7 | 2013 | View substance registered dossier |
| BASF Grenzach GmbH | Köchlinstr. 1 79639 Grenzach-Wyhlen Germany | Germany | Cease Manufacture | 5-chloro-2-(4-chlorophenoxy)phenol; [DCPP] | 429-290-0 | 3380-30-1 | 2017 | View substance registered dossier |
| Fine Organics Limited | Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom | United Kingdom | No longer Valid | 5-CHLOROTHIOPHENE-2-CARBOXYLIC ACID | 480-060-6 | 24065-33-6 | 2021 | View substance registered dossier |
| Harlan Laboratories Ltd 07 | Shardlow Business Park London Road DE72 2GD Shardlow Derbyshire United Kingdom | United Kingdom | Cease Manufacture | 5-endo-decyl-bicyclo[hept-2-ene / 5-endo/decyl-bicyclo[2.2.1]hept-2-ene | 435-040-1 | - | 2012 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 5-endo-hexyl-bicyclo[2.2.1]hept-2-ene | 435-000-3 | 22094-83-3 | - | View substance registered dossier |
| - | - | - | - | 5-ethoxy-1,3-dimethyl-1,3-dihydroindol-2-one | 415-630-5 | - | - | View substance registered dossier |
| Symrise AG | Mühlenfeldstraße 1 37603 Holzminden Germany | Germany | Active | 5-ethoxy-5H-furan-2-one | 428-330-4 | 2833-30-9 | 2011 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. | - | - | Active | 5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one | 414-470-3 | 95885-13-5 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | 5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one | 414-470-3 | 95885-13-5 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. | - | - | Active | 5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one | 414-470-3 | 95885-13-5 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 5-exo-butyl-bicyclo[2.2.1]hept-2-ene (80:20); reaction mass of: 5-endo-butyl-bicyclo[2.2.1]hept-2-ene | 435-180-3 | - | - | View substance registered dossier |
| - | - | - | - | 5-FR | 446-200-5 | - | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 5-Hexyl-2-methyl pyridine | 414-530-9 | 710-40-7 | - | View substance registered dossier |
| - | - | - | - | 5-Hexyl-2-methyl pyridine | 414-530-9 | 710-40-7 | - | View substance registered dossier |
| Cambrex Karlskoga AB | Bjorkborns Industriomrade 69185 Karlskoga Sweden | Sweden | Active | 5-Methoxy-2-tetralone | 457-080-9 | - | 2015; 2018 | View substance registered dossier |
| RHODIA OPERATIONS | 52 rue de la Haie Coq 93300 AUBERVILLIERS France | France | Cease Manufacture | 5-methyl-1-phenylhexane-1,3-dione | 400-360-2 | - | 2019 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. | - | - | Active | 5-NQD | 406-450-8 | - | - | View substance registered dossier |
| Covance Clinical Development SA 151 | Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain | Spain | Active | 5-NQD | 406-450-8 | - | 2011 | View substance registered dossier |
| WeylChem Lamotte S.A.S | Rue du Flottage B.P. 1 60350 Trosly Breuil France | France | Active | 5-tert-Butyl-2-methylbenzenethiol | 438-520-9 | 7340-90-1 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. | - | - | Active | 5-tert-butylpyrazol-3-ylamine | 450-360-1 | 82560-12-1 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. | - | - | Active | 5-thiazolylmethanol | 414-780-9 | 38585-74-9 | - | View substance registered dossier |
| Abbott | 30 Tower View ME19 4UY Kings Hill Kent United Kingdom | United Kingdom | Cease Manufacture | 5-thiazolylmethanol | 414-780-9 | 38585-74-9 | 2018 | View substance registered dossier |
| Huntsman Textile Effects (Germany) GmbH | Rehlinger Str. 1 D-86462 Langweid a.Lech Germany | Germany | Active | 5-{4-[5-amino-2-[4-(2-sulfoxyethylsulfonyl)phenylazo]-4-sulfo-phenylamino]-6-chloro-1,3,5-triazin-2-ylamino}-4-hydroxy-3-(1-sulfo-naphthalen-2-ylazo)-naphthalene-2,7-disulfonicacid sodium salt. | 418-340-7 | 157707-94-3 | 2010 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. | - | - | Active | 5-{4-[5-amino-2-[4-(2-sulfoxyethylsulfonyl)phenylazo]-4-sulfo-phenylamino]-6-chloro-1,3,5-triazin-2-ylamino}-4-hydroxy-3-(1-sulfo-naphthalen-2-ylazo)-naphthalene-2,7-disulfonicacid sodium salt. | 418-340-7 | 157707-94-3 | - | View substance registered dossier |
| IVICT Europe GmbH | Kennedydamm 19 40476 Düsseldorf Germany | Germany | Cease Manufacture | 6'-(isobutylethylamino)-3'-methyl-2'-phenylaminospiro[isobenzo-2-oxofuran-7,9'-[9H]-xanthene] | 410-890-6 | 95235-29-3 | 2017 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 6'-(isobutylethylamino)-3'-methyl-2'-phenylaminospiro[isobenzo-2-oxofuran-7,9'-[9H]-xanthene] | 410-890-6 | 95235-29-3 | - | View substance registered dossier |
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