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Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The REACH Registered substance portal was updated on 9th November 2020; the REACH registered factsheets were further updated on 21st December 2020. Details of the improvements can be found at Dissemination Platform Updates. Reprocessing the entire dataset is ongoing since 21 December 2020. ECHA is making all possible efforts to make the improvements and additional data visible with the shortest delay.
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
Last updated 07 March 2021. Database contains 23184 unique substances and contains information from 93714 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
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Uses and exposure
Life cycle:
  • Consumer Uses
  • Article service life
  • Widespread uses by professional workers
  • Formulation or re-packing
  • Uses at industrial sites
  • Manufacture
Category:
Details
2,2'-{octahydro-1H-4,7-methanoindene-2,5-diylbis[(2,1-phenylene)oxymethylene]}bis(oxirane)
943-519-6 - Active Full Joint ≥ 1 to < 10 tonnes 04-07-2019 View substance registered dossier
2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl N-[6-({[(2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl)oxy]carbonyl}amino)-3,3,5-trimethylhexyl]carbamate 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl N-[6-({[(2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl)oxy]carbonyl}amino)-3,5,5-trimethylhexyl]carbamate
938-105-7 - Active Full Individual ≥ 0 to < 10 tonnes 18-10-2012 View substance registered dossier
2,2,3,3,4,4,5,5,6,6-decafluoro-6-trifluorovinyloxyhexanenitrile
443-050-2 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
2,2,6,6,7,8,8-HEPTAMETHYL-4,5,6,7,8,8B-HEXAHYDRO-3AH-INDENO[4,5-D][1,3]DIOXOLE
457-070-4 - Active NONS Joint Tonnage data confidential 09-09-2019 View substance registered dossier
2,2,6,6,7,8,8-HEPTAMETHYL-4,5,6,7,8,8B-HEXAHYDRO-3AH-INDENO[4,5-D][1,3]DIOXOLE
457-070-4 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2,2,6,6-tetramethyl-4-piperidyl acrylate
415-090-0 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2,2,6,6-tetramethyl-4-substituted-piperidinyl-1-oxy
482-430-2 - Active Full Individual ≥ 0 to < 10 tonnes 03-02-2016 View substance registered dossier
2,2-bis(3,5-dibromo-4-(3-acryloyloxy-2-hydroxypropoxy)phenyl)propane
436-220-2 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
2,2-bis({[3-(4-ethylpiperazin-1-yl)propanoyl]oxy}methyl)butyl 3-(4-ethylpiperazin-1-yl)propanoate
700-404-3 - Active Full Individual ≥ 1 to < 10 tonnes 19-05-2010 View substance registered dossier
2,2-bis[(allyloxy)methyl]butyl (3-{[({2,2-bis[(allyloxy)methyl]butoxy}carbonyl)amino]methyl}-3,5,5-trimethylcyclohexyl)carbamate
946-937-7 - Active Full Joint ≥ 1 to < 10 tonnes 29-03-2018 View substance registered dossier
2,2-dialkyl-4-hydroxymethyl-1,3-dioxolane; reaction products with ethylene oxide (alkyl is C1-12 and the sum to C13, average degree of ethoxylation is 3.5)
430-580-4 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
2,2-dimethyl-3-(m-tolyl)propanal
440-720-6 - Active Intermediate Joint Intermediate use only 17-04-2020 View substance registered dossier
2,2-dimethyl-3-(m-tolyl)propanal
440-720-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2,2-dimethyl-4,7-dihydro-1,3-dioxepine
445-850-7 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2,2-dimethyl-4H-1,3,2-benzodioxasilin-4-one
418-660-7 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
2,20:3,19-Dimethano-2,3,4a,5a,6a,7a,8a,9a,10a,11a, 12a,13a,14a,15a,16a,17a,19 ,20,21a,22a,23a,24a,25a,26a,27a,28a,29a,30a,31a,32a,33a,34a-dotriacontaazabispentaleno [1''',6''':5'',6'',7''] cycloocta[1'',2'',3'':3'',4'']pentaleno[1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-gh:1',2',3'-g'h']cycloocta[1,2,3-cd:5,6,7-c'd']dipentalene-1,4,6,8,10,12,14,16,18,21,23,25,27,29,31,33-hexadecone, hexadecahydro-, stereoisomer,2,18:3,17-Dimethano-2,3, ,4a,5a,6a,7a,8a,9a,10a,11a,12a,13a,14a,15a,17,18,19a, 20a,21a,22a,23a,24a, 25a,26a,27a,28a,29a,30a-octacosaazabispentaleno[1''',6''':5'',6'',7'']cycloocta [1'',2'',3'':3'',4''] pentaleno[1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-cd:1',2',3'-gh]pentalene-1,4,6,8,10,12,14,16,19,21,23,25,27,29-tetradecone, tetradecahydro-, stereoisomer, 1H,4H,12H,15H-2,14:3,13-Dimethano-5H,6H,7H,8H,9H,10H,11H,16H,17H,18H,19H,20H,21H,22H-2,3,4a,5a,6a,7a,8a,9a,10a,11a,13,14,15a,16a,17a,18a,19a,20a,21a,22a-eicosaazabispentaleno [1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-cd:1',2',3'-gh]pentalene-1,4,6,8,10,12,15,17,19,21-decone, decahydro-, stereoisomer
946-188-6 - Active Full Joint ≥ 1 to < 10 tonnes 16-10-2020 View substance registered dossier
2,2`-[6-(phenylamino)-heteromonocycle-2,4-diyl]diphenol
- - Active Full Individual ≥ 0 to < 10 tonnes 15-02-2013 View substance registered dossier
2,2’-dimethyl-2,2’-azoheptanenitrile; 2-methylheptanenitrile-2-azo-2’-(2’-methylbutanenitrile); 2-methylheptanenitrile-2-azo-2’-(2’-methylpropanenitrile); 2-methylpentanenitrile-2-azo-2’-(2’-methylpropanenitrile); reaction mass of: 2,2’-dimethyl-2,2’-azobutanenitrile
429-710-2 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
2,3,4,4'-tetrakis(6-diazo-5,6-dihydro-5-oxo-1-naphthylsulfonato)benzophenone
424-190-3 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2,3,4,6-Tetra-O-benzyl-D-glucopyranose
432-870-6 - Active Intermediate Joint Intermediate use only 24-09-2019 View substance registered dossier
2,3,4,6-Tetra-O-benzyl-D-glucopyranose
432-870-6 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
2,3-Difluorpropoxybenzol
485-470-9 - Active NONS Joint Tonnage data confidential 06-01-2020 View substance registered dossier
2,3-dihydro-2-methyl-1H-indol-1-amine p-toluenesulfonate
928-401-4 - Active Intermediate Joint Intermediate use only 18-05-2018 View substance registered dossier
2,3-dimethyl-2-[(3-methylbicyclo[2.2.1]hept-2-yl)methyl]bicyclo[2.2.1]heptane; reaction mass of: 1,7-dimethyl-2-[(3-methylbicyclo[2.2.1]hept-2-yl)methyl]bicyclo[2.2.1]heptane
427-040-5 - Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
2,4,6-Tri(2,4-dihydroxyphenyl)-1,3,5-triazine
700-796-6 - Active Intermediate Individual Intermediate use only 13-02-2012 View substance registered dossier
2,4,6-triisobutyl-1,3,5-dithiazinane
457-290-0 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2,4,6-Trimethylphenylacetyl chloride
462-070-2 - Active Intermediate Joint Intermediate use only 27-05-2019 View substance registered dossier
2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine
426-040-2 - Active Full Joint ≥ 100 tonnes 23-11-2017 View substance registered dossier
2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine
426-040-2 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
2,4,8,10-tetra(tert-butyl)-6-hydroxy-12H-dibenzo-[d,g][1,3,2]dioxaphosphocin 6-oxide, lithium salt
458-880-0 - Active NONS Individual Tonnage data confidential 24-09-2013 View substance registered dossier
2,4-bis[N'-(4-methylphenyl)ureido]toluene
411-790-5 - null Full Joint 0 - 10 tonnes per annum 02-10-2020 View substance registered dossier
2,4-bis[N'-(4-methylphenyl)ureido]toluene
411-790-5 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
2,4-dichlorophenyl [4-(bromomethyl)phenoxy]acetate
432-330-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2,4-DPZ
434-170-6 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
2,5-dichloro-3,6-bis{4-[(2-hydroxyethyl)amino]-3-[(2-hydroxyethyl)sulfonyl]anilino}-1,4-benzoquinone
426-700-1 - Cease Manufacture NONS Individual Cease manufacture 28-02-2011 View substance registered dossier
2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenylamine
414-940-8 - Cease Manufacture Intermediate Individual Cease manufacture 16-07-2015 View substance registered dossier
2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenylamine
414-940-8 - Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
2,5-Dihydroxy-3,6-dimethyl-3,6-bis(dihydroxyphosphinyl)- 1,4,2,5-dioxadiphosphorinane-2,5-dioxide
921-798-5 - Active Intermediate Joint Intermediate use only 21-09-2018 View substance registered dossier
2,5-dihydroxy-3,6-dimethyl-3,6-bis(dihydroxyphosphinyl)-1,4,2,5-dioxadiphosphorane-2,5-dioxide, hexasodium salt
928-304-7 - Active Full Joint ≥ 1 to < 10 tonnes 25-09-2018 View substance registered dossier
2,5-Dimethylphenylacetyl-chloride
470-780-9 - Active Intermediate Joint Intermediate use only 28-03-2018 View substance registered dossier
2,5-dioxopyrrolidin-1-yl N-{[methyl[[2-(1-methylethyl)-4-thiazolyl]methyl]amino]carbonyl}-.sc.l.sc.-valinate
424-660-8 - Active Intermediate Joint Intermediate use only 13-06-2018 View substance registered dossier
2,5-dioxopyrrolidin-1-yl N-{[methyl[[2-(1-methylethyl)-4-thiazolyl]methyl]amino]carbonyl}-.sc.l.sc.-valinate
424-660-8 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
2,5-diphenyloxazole-4-sulfonic acid
421-210-2 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2,5-furandione, dihydro-, mono- C18- alkenyl derivs. reaction products with potassium hydroxide
947-318-4 - Active Full Joint ≥ 0 to < 10 tonnes 23-03-2018 View substance registered dossier
2,6,6,7,8,8-hexamethyl-3,3a,4,5,5a,6,7,8-octahydro-2H-indeno[4,5-b]furan, 1,1,2,3,3-pentamethyl-1,2,3,5,6,7-hexahydro-4H-inden-4-one and rel-(3aR,7aR)-1,1,2,3,3-pentamethyloctahydro-4H-inden-4-one
946-273-8 - Active Intermediate Joint Intermediate use only 27-11-2017 View substance registered dossier
2,6,6-trimethylcyclohex-1-enecarbonitrile
921-141-2 - Active Intermediate Joint Intermediate use only 19-10-2015 View substance registered dossier
2,6,6-trimethylcyclohexa-1,3-dienecarbonitrile
917-351-9 - Active Intermediate Individual Intermediate use only 02-12-2015 View substance registered dossier
2,6,7-trioxa-1-phosphabicyclo[2.2.2]octane-4-methanol, 1-oxide
416-540-9 - Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
2,6-bis({[bis(2-hydroxyethyl)amino]methyl})-4-[2-(3-{[bis(2-hydroxyethyl)amino]methyl}-4-hydroxyphenyl)propan-2-yl]phenol; 2,6-bis({[bis(2-hydroxyethyl)amino]methyl})-4-[2-(4-hydroxyphenyl)propan-2-yl]phenol; 2-[(2-hydroxyethyl)amino]ethan-1-ol; 2-{[bis(2-hydroxyethyl)amino]methyl}-4-[2-(3-{[bis(2-hydroxyethyl)amino]methyl}-4-hydroxyphenyl)propan-2-yl]phenol; 2-{[bis(2-hydroxyethyl)amino]methyl}-4-[2-(4-hydroxyphenyl)propan-2-yl]phenol; 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol
943-503-9 - Active Full Joint ≥ 100 to < 1 000 tonnes 12-12-2017 View substance registered dossier
2,6-dihydroxy-4-methyl-1-[3-(methylaminio)propyl]pyridine-1-sulfate salt
931-673-7 - Active Intermediate Joint Intermediate use only 11-01-2016 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Huntsman Advanced Materials (Europe) BV Everslaan 45 B-3078 Everberg Belgium Belgium Active 2,2'-{octahydro-1H-4,7-methanoindene-2,5-diylbis[(2,1-phenylene)oxymethylene]}bis(oxirane) 943-519-6 - 2016; 2019 View substance registered dossier
[Confidential] - - - 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl N-[6-({[(2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl)oxy]carbonyl}amino)-3,3,5-trimethylhexyl]carbamate 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl N-[6-({[(2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl)oxy]carbonyl}amino)-3,5,5-trimethylhexyl]carbamate 938-105-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 2,2,3,3,4,4,5,5,6,6-decafluoro-6-trifluorovinyloxyhexanenitrile 443-050-2 - - View substance registered dossier
- - - - 2,2,3,3,4,4,5,5,6,6-decafluoro-6-trifluorovinyloxyhexanenitrile 443-050-2 - - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active 2,2,6,6,7,8,8-HEPTAMETHYL-4,5,6,7,8,8B-HEXAHYDRO-3AH-INDENO[4,5-D][1,3]DIOXOLE 457-070-4 - 2012; 2019 View substance registered dossier
- - - - 2,2,6,6,7,8,8-HEPTAMETHYL-4,5,6,7,8,8B-HEXAHYDRO-3AH-INDENO[4,5-D][1,3]DIOXOLE 457-070-4 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active 2,2,6,6-tetramethyl-4-piperidyl acrylate 415-090-0 - - View substance registered dossier
Nufarm GmbH & Co.KG OR St.-Peter-Str.25 4021 Linz Austria Austria Active 2,2,6,6-tetramethyl-4-substituted-piperidinyl-1-oxy 482-430-2 - 2014; 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2,2-bis(3,5-dibromo-4-(3-acryloyloxy-2-hydroxypropoxy)phenyl)propane 436-220-2 - - View substance registered dossier
Laborchemie Apolda GmbH Utenbacher Straße 72-74 99510 Apolda Germany Germany Active 2,2-bis({[3-(4-ethylpiperazin-1-yl)propanoyl]oxy}methyl)butyl 3-(4-ethylpiperazin-1-yl)propanoate 700-404-3 - - View substance registered dossier
PPG Europe B.V. - OR1 Amsterdamseweg 14 1422 AD Uithoorn Netherlands Netherlands Active 2,2-bis[(allyloxy)methyl]butyl (3-{[({2,2-bis[(allyloxy)methyl]butoxy}carbonyl)amino]methyl}-3,5,5-trimethylcyclohexyl)carbamate 946-937-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2,2-dialkyl-4-hydroxymethyl-1,3-dioxolane; reaction products with ethylene oxide (alkyl is C1-12 and the sum to C13, average degree of ethoxylation is 3.5) 430-580-4 - - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active 2,2-dimethyl-3-(m-tolyl)propanal 440-720-6 - 2011; 2016; 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 2,2-dimethyl-3-(m-tolyl)propanal 440-720-6 - - View substance registered dossier
Borregaard AS Hjalmar Wessels vei 6 1701 Sarpsborg Norway Norway Active 2,2-dimethyl-4,7-dihydro-1,3-dioxepine 445-850-7 - - View substance registered dossier
- - - - 2,2-dimethyl-4H-1,3,2-benzodioxasilin-4-one 418-660-7 - - View substance registered dossier
WeylChem Lamotte S.A.S Rue du Flottage B.P. 1 60350 Trosly Breuil France France Active 2,20:3,19-Dimethano-2,3,4a,5a,6a,7a,8a,9a,10a,11a, 12a,13a,14a,15a,16a,17a,19 ,20,21a,22a,23a,24a,25a,26a,27a,28a,29a,30a,31a,32a,33a,34a-dotriacontaazabispentaleno [1''',6''':5'',6'',7''] cycloocta[1'',2'',3'':3'',4'']pentaleno[1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-gh:1',2',3'-g'h']cycloocta[1,2,3-cd:5,6,7-c'd']dipentalene-1,4,6,8,10,12,14,16,18,21,23,25,27,29,31,33-hexadecone, hexadecahydro-, stereoisomer,2,18:3,17-Dimethano-2,3, ,4a,5a,6a,7a,8a,9a,10a,11a,12a,13a,14a,15a,17,18,19a, 20a,21a,22a,23a,24a, 25a,26a,27a,28a,29a,30a-octacosaazabispentaleno[1''',6''':5'',6'',7'']cycloocta [1'',2'',3'':3'',4''] pentaleno[1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-cd:1',2',3'-gh]pentalene-1,4,6,8,10,12,14,16,19,21,23,25,27,29-tetradecone, tetradecahydro-, stereoisomer, 1H,4H,12H,15H-2,14:3,13-Dimethano-5H,6H,7H,8H,9H,10H,11H,16H,17H,18H,19H,20H,21H,22H-2,3,4a,5a,6a,7a,8a,9a,10a,11a,13,14,15a,16a,17a,18a,19a,20a,21a,22a-eicosaazabispentaleno [1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-cd:1',2',3'-gh]pentalene-1,4,6,8,10,12,15,17,19,21-decone, decahydro-, stereoisomer 946-188-6 - - View substance registered dossier
Aqdot Ireland Limited 88 Harcourt Street 2, D02Dk18 Dublin Ireland Ireland Active 2,20:3,19-Dimethano-2,3,4a,5a,6a,7a,8a,9a,10a,11a, 12a,13a,14a,15a,16a,17a,19 ,20,21a,22a,23a,24a,25a,26a,27a,28a,29a,30a,31a,32a,33a,34a-dotriacontaazabispentaleno [1''',6''':5'',6'',7''] cycloocta[1'',2'',3'':3'',4'']pentaleno[1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-gh:1',2',3'-g'h']cycloocta[1,2,3-cd:5,6,7-c'd']dipentalene-1,4,6,8,10,12,14,16,18,21,23,25,27,29,31,33-hexadecone, hexadecahydro-, stereoisomer,2,18:3,17-Dimethano-2,3, ,4a,5a,6a,7a,8a,9a,10a,11a,12a,13a,14a,15a,17,18,19a, 20a,21a,22a,23a,24a, 25a,26a,27a,28a,29a,30a-octacosaazabispentaleno[1''',6''':5'',6'',7'']cycloocta [1'',2'',3'':3'',4''] pentaleno[1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-cd:1',2',3'-gh]pentalene-1,4,6,8,10,12,14,16,19,21,23,25,27,29-tetradecone, tetradecahydro-, stereoisomer, 1H,4H,12H,15H-2,14:3,13-Dimethano-5H,6H,7H,8H,9H,10H,11H,16H,17H,18H,19H,20H,21H,22H-2,3,4a,5a,6a,7a,8a,9a,10a,11a,13,14,15a,16a,17a,18a,19a,20a,21a,22a-eicosaazabispentaleno [1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-cd:1',2',3'-gh]pentalene-1,4,6,8,10,12,15,17,19,21-decone, decahydro-, stereoisomer 946-188-6 - 2019 View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom No longer Valid 2,20:3,19-Dimethano-2,3,4a,5a,6a,7a,8a,9a,10a,11a, 12a,13a,14a,15a,16a,17a,19 ,20,21a,22a,23a,24a,25a,26a,27a,28a,29a,30a,31a,32a,33a,34a-dotriacontaazabispentaleno [1''',6''':5'',6'',7''] cycloocta[1'',2'',3'':3'',4'']pentaleno[1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-gh:1',2',3'-g'h']cycloocta[1,2,3-cd:5,6,7-c'd']dipentalene-1,4,6,8,10,12,14,16,18,21,23,25,27,29,31,33-hexadecone, hexadecahydro-, stereoisomer,2,18:3,17-Dimethano-2,3, ,4a,5a,6a,7a,8a,9a,10a,11a,12a,13a,14a,15a,17,18,19a, 20a,21a,22a,23a,24a, 25a,26a,27a,28a,29a,30a-octacosaazabispentaleno[1''',6''':5'',6'',7'']cycloocta [1'',2'',3'':3'',4''] pentaleno[1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-cd:1',2',3'-gh]pentalene-1,4,6,8,10,12,14,16,19,21,23,25,27,29-tetradecone, tetradecahydro-, stereoisomer, 1H,4H,12H,15H-2,14:3,13-Dimethano-5H,6H,7H,8H,9H,10H,11H,16H,17H,18H,19H,20H,21H,22H-2,3,4a,5a,6a,7a,8a,9a,10a,11a,13,14,15a,16a,17a,18a,19a,20a,21a,22a-eicosaazabispentaleno [1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-cd:1',2',3'-gh]pentalene-1,4,6,8,10,12,15,17,19,21-decone, decahydro-, stereoisomer 946-188-6 - 2021 View substance registered dossier
Archroma Germany GmbH Kasteler Str. 45 65203 Wiesbaden Germany Germany Active 2,2`-[6-(phenylamino)-heteromonocycle-2,4-diyl]diphenol - - 2008; 2011; 2013 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active 2,2’-dimethyl-2,2’-azoheptanenitrile; 2-methylheptanenitrile-2-azo-2’-(2’-methylbutanenitrile); 2-methylheptanenitrile-2-azo-2’-(2’-methylpropanenitrile); 2-methylpentanenitrile-2-azo-2’-(2’-methylpropanenitrile); reaction mass of: 2,2’-dimethyl-2,2’-azobutanenitrile 429-710-2 - - View substance registered dossier
- - - - 2,3,4,4'-tetrakis(6-diazo-5,6-dihydro-5-oxo-1-naphthylsulfonato)benzophenone 424-190-3 - - View substance registered dossier
Biosynth s.r.o. Nobelova 34 83605 Bratislava Slovakia Slovakia Active 2,3,4,6-Tetra-O-benzyl-D-glucopyranose 432-870-6 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 2,3,4,6-Tetra-O-benzyl-D-glucopyranose 432-870-6 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 2,3-Difluorpropoxybenzol 485-470-9 - 2020 View substance registered dossier
Laboratori Alchemia Srl San Faustino 68 20134 Milan Italy Italy Active 2,3-dihydro-2-methyl-1H-indol-1-amine p-toluenesulfonate 928-401-4 - - View substance registered dossier
Covance Clinical Development SA 046 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active 2,3-dimethyl-2-[(3-methylbicyclo[2.2.1]hept-2-yl)methyl]bicyclo[2.2.1]heptane; reaction mass of: 1,7-dimethyl-2-[(3-methylbicyclo[2.2.1]hept-2-yl)methyl]bicyclo[2.2.1]heptane 427-040-5 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2,3-dimethyl-2-[(3-methylbicyclo[2.2.1]hept-2-yl)methyl]bicyclo[2.2.1]heptane; reaction mass of: 1,7-dimethyl-2-[(3-methylbicyclo[2.2.1]hept-2-yl)methyl]bicyclo[2.2.1]heptane 427-040-5 - - View substance registered dossier
BASF Grenzach GmbH Köchlinstr. 1 79639 Grenzach-Wyhlen Germany Germany Active 2,4,6-Tri(2,4-dihydroxyphenyl)-1,3,5-triazine 700-796-6 - - View substance registered dossier
- - - - 2,4,6-triisobutyl-1,3,5-dithiazinane 457-290-0 - - View substance registered dossier
WeylChem Lamotte S.A.S Rue du Flottage B.P. 1 60350 Trosly Breuil France France Active 2,4,6-Trimethylphenylacetyl chloride 462-070-2 - 2016; 2019 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 2,4,6-Trimethylphenylacetyl chloride 462-070-2 - 2010; 2016 View substance registered dossier
KTR Europe GmbH Mergenthalerallee 77 65760 Eschborn Germany Germany Active 2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine 426-040-2 - 2011; 2013; 2014; 2017 View substance registered dossier
ICL Europe Coöperatief U.A. (OR1) Koningin Wilhelminaplein 30 Prinsenhof 1062 KR Amsterdam Netherlands Netherlands Active 2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine 426-040-2 - 2010; 2011; 2012; 2014; 2015; 2017 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine 426-040-2 - - View substance registered dossier
ADEKA POLYMER ADDITIVES EUROPE SAS 13 rue du 17 Novembre FR-68100 MULHOUSE France France Active 2,4,8,10-tetra(tert-butyl)-6-hydroxy-12H-dibenzo-[d,g][1,3,2]dioxaphosphocin 6-oxide, lithium salt 458-880-0 - 2013 View substance registered dossier
Charles River Laboratories Den Bosch B.V. OR20 Hambakenwetering 7 5231DD 's-Hertogenbosch Netherlands - - 2,4-bis[N'-(4-methylphenyl)ureido]toluene 411-790-5 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2,4-bis[N'-(4-methylphenyl)ureido]toluene 411-790-5 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2,4-dichlorophenyl [4-(bromomethyl)phenoxy]acetate 432-330-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2,4-DPZ 434-170-6 - - View substance registered dossier
DyStar Colours Distribution GmbH Am Prime-Parc 12 65479 Raunheim Germany Germany Cease Manufacture 2,5-dichloro-3,6-bis{4-[(2-hydroxyethyl)amino]-3-[(2-hydroxyethyl)sulfonyl]anilino}-1,4-benzoquinone 426-700-1 - 2019 View substance registered dossier
AllessaProduktion GmbH Alt-Fechenheim 34 60386 Frankfurt am Main Germany Germany Cease Manufacture 2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenylamine 414-940-8 - 2019 View substance registered dossier
Syngenta Ltd Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom United Kingdom Cease Manufacture 2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenylamine 414-940-8 - 2013 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenylamine 414-940-8 - - View substance registered dossier
Cytec Industries BV OR for UK Burgemeester van Lierplein 75 3134 ZB Vlaardingen Netherlands Netherlands Active 2,5-Dihydroxy-3,6-dimethyl-3,6-bis(dihydroxyphosphinyl)- 1,4,2,5-dioxadiphosphorinane-2,5-dioxide 921-798-5 - 2016; 2018 View substance registered dossier
Thomas Swan & Co. Ltd. Rotary Way DH8 7ND Consett Co. Durham United Kingdom United Kingdom No longer Valid 2,5-dihydroxy-3,6-dimethyl-3,6-bis(dihydroxyphosphinyl)-1,4,2,5-dioxadiphosphorane-2,5-dioxide, hexasodium salt 928-304-7 - 2021 View substance registered dossier
Cytec Industries BV OR for UK Burgemeester van Lierplein 75 3134 ZB Vlaardingen Netherlands Netherlands Active 2,5-dihydroxy-3,6-dimethyl-3,6-bis(dihydroxyphosphinyl)-1,4,2,5-dioxadiphosphorane-2,5-dioxide, hexasodium salt 928-304-7 - - View substance registered dossier
WeylChem Lamotte S.A.S Rue du Flottage B.P. 1 60350 Trosly Breuil France France Cease Manufacture 2,5-Dimethylphenylacetyl-chloride 470-780-9 - 2019 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 2,5-Dimethylphenylacetyl-chloride 470-780-9 - 2010 View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active 2,5-dioxopyrrolidin-1-yl N-{[methyl[[2-(1-methylethyl)-4-thiazolyl]methyl]amino]carbonyl}-.sc.l.sc.-valinate 424-660-8 - 2011; 2018 View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid 2,5-dioxopyrrolidin-1-yl N-{[methyl[[2-(1-methylethyl)-4-thiazolyl]methyl]amino]carbonyl}-.sc.l.sc.-valinate 424-660-8 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2,5-diphenyloxazole-4-sulfonic acid 421-210-2 - - View substance registered dossier
Italmatch Chemicals SpA - OR 2 Via Magazzini del Cotone 17 – modulo 4 16128 genova Italy Italy Active 2,5-furandione, dihydro-, mono- C18- alkenyl derivs. reaction products with potassium hydroxide 947-318-4 - - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active 2,6,6,7,8,8-hexamethyl-3,3a,4,5,5a,6,7,8-octahydro-2H-indeno[4,5-b]furan, 1,1,2,3,3-pentamethyl-1,2,3,5,6,7-hexahydro-4H-inden-4-one and rel-(3aR,7aR)-1,1,2,3,3-pentamethyloctahydro-4H-inden-4-one 946-273-8 - - View substance registered dossier
Givaudan Iberica SA Pla d'en Batlle s/n 08470 San Celoni Barcelona Spain Spain Active 2,6,6-trimethylcyclohex-1-enecarbonitrile 921-141-2 - - View substance registered dossier
Givaudan Iberica SA Pla d'en Batlle s/n 08470 San Celoni Barcelona Spain Spain Active 2,6,6-trimethylcyclohexa-1,3-dienecarbonitrile 917-351-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2,6,7-trioxa-1-phosphabicyclo[2.2.2]octane-4-methanol, 1-oxide 416-540-9 - - View substance registered dossier
CS Regulatory Ireland Ltd. in its legal capacity as OR for LANXESS Solutions UK Ltd Alexandra House The Sweepstakes D04 C7H2 Dublin Ballsbridge Ireland Ireland Active 2,6,7-trioxa-1-phosphabicyclo[2.2.2]octane-4-methanol, 1-oxide 416-540-9 - - View substance registered dossier
Plixxent B.V. Korte Groningerweg 1A 9607 Foxhol Netherlands Netherlands Active 2,6-bis({[bis(2-hydroxyethyl)amino]methyl})-4-[2-(3-{[bis(2-hydroxyethyl)amino]methyl}-4-hydroxyphenyl)propan-2-yl]phenol; 2,6-bis({[bis(2-hydroxyethyl)amino]methyl})-4-[2-(4-hydroxyphenyl)propan-2-yl]phenol; 2-[(2-hydroxyethyl)amino]ethan-1-ol; 2-{[bis(2-hydroxyethyl)amino]methyl}-4-[2-(3-{[bis(2-hydroxyethyl)amino]methyl}-4-hydroxyphenyl)propan-2-yl]phenol; 2-{[bis(2-hydroxyethyl)amino]methyl}-4-[2-(4-hydroxyphenyl)propan-2-yl]phenol; 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol 943-503-9 - 2017 View substance registered dossier
ARCHROMA IBÉRICA, S.L. ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain Spain Active 2,6-dihydroxy-4-methyl-1-[3-(methylaminio)propyl]pyridine-1-sulfate salt 931-673-7 - 2016 View substance registered dossier

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