Registered substances
Registered substances
In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).
ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.
As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).
In the portal results table are presented:
- Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
- Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
- Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
- Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
- Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
- Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
- Link to the full factsheet.
A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.
Please note:
- The REACH Registered substance portal was updated on 9th November 2020; the REACH registered factsheets were further updated on 21st December 2020. Details of the improvements can be found at Dissemination Platform Updates. Reprocessing the entire dataset is ongoing since 21 December 2020. ECHA is making all possible efforts to make the improvements and additional data visible with the shortest delay.
- The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
Further information
- Registered substances information
- How to determine what will be published (Data Submission Manual 15)
- Understanding REACH Regulation
- Q&A on registered substances
- What is an Infocard? [PDF]
- What is a Registered substance Factsheet? [PDF]
- eChemPortal
- REACH study results download
- REACH Regulation
- ECHA Legal notice
Last updated 22 February 2021. Database contains 23117 unique substances and contains information from 96052 dossiers.
| Registrant/Supplier | Address | Country | Registration Status | Name | EC / List no. | CAS no. | Last update year | Details |
|---|---|---|---|---|---|---|---|---|
| La Mesta Bourgogne | Campus industriel Le Grand Chalon en Bourgogne Route de Demigny - BP21 71102 Chalon-sur-Saone France | France | Active | 3-amino-4-chlorobenzoic acid, hexadecyl ester | 419-700-6 | 143269-74-3 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. | - | - | Active | 3-amino-4-chlorobenzoic acid, hexadecyl ester | 419-700-6 | 143269-74-3 | - | View substance registered dossier |
| Huntsman Textile Effects (Germany) GmbH | Rehlinger Str. 1 D-86462 Langweid a.Lech Germany | Germany | Cease Manufacture | 3-amino-4-hydroxy-N-(2-methoxyethyl)benzenesulfonamide | 411-520-6 | 112195-27-4 | 2014 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. | - | - | Active | 3-amino-5-tert-butylisoxazole hydrochloride | 404-840-2 | 164578-13-6 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 3-amino-5-tert-butylisoxazole hydrochloride | 404-840-2 | 164578-13-6 | - | View substance registered dossier |
| MOEHS CANTABRA | P.I.Requejada Z-23 39313 Polanco Cantabria Spain | - | - | 3-Amino-tricyclo[3,3,1,13,7]decan-1-ol | 450-050-6 | - | - | View substance registered dossier |
| - | - | - | - | 3-Amino-tricyclo[3,3,1,13,7]decan-1-ol | 450-050-6 | - | - | View substance registered dossier |
| Novartis International Pharmaceutical ltd., Branch Ireland | Ringaskiddy IE Ringaskiddy Cork Ireland | - | - | 3-Amino-tricyclo[3,3,1,13,7]decan-1-ol | 450-050-6 | - | - | View substance registered dossier |
| - | - | - | - | 3-aminobenzylamine | 412-230-2 | 4403-70-7 | - | View substance registered dossier |
| DyStar Colours Distribution GmbH | Am Prime-Parc 12 65479 Raunheim Germany | - | - | 3-aminobenzylamine | 412-230-2 | 4403-70-7 | - | View substance registered dossier |
| DOW BENELUX B.V. - OR2 | Postbus 48 4530 AA Terneuzen Netherlands | Netherlands | Cease Manufacture | 3-Aminooctan-4-ol | 482-070-6 | 1001354-72-8 | 2015 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. | - | - | Active | 3-azidosulfonylbenzoic acid | 405-310-3 | 15980-11-7 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 3-benzyl-exo-6-nitro-2,4-dioxo-3-aza-cis-bicyclo[3.1.0]hexane | 426-750-2 | 151860-15-0 | - | View substance registered dossier |
| - | - | - | - | 3-butyl-1-methyl-1H-imidazol-3-ium chloride | 460-120-8 | 79917-90-1 | - | View substance registered dossier |
| BASF SE | Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany | - | - | 3-butyl-1-methyl-1H-imidazol-3-ium chloride | 460-120-8 | 79917-90-1 | - | View substance registered dossier |
| - | - | - | - | 3-Carbamyl-1-methylpyridinium Chloride | 463-670-7 | 1005-24-9 | - | View substance registered dossier |
| Cytec Industries BV OR for UK | Burgemeester van Lierplein 75 3134 ZB Vlaardingen Netherlands | Netherlands | Cease Manufacture | 3-chloro-2,4-difluoronitrobenzene | 411-980-8 | 3847-58-3 | 2019 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority. | - | - | Active | 3-chloro-2-(isopropylthio)aniline | 421-700-6 | 179104-32-6 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. | - | - | Active | 3-chloro-4-(3-fluorobenzyloxy)aniline | 445-590-4 | 202197-26-0 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 3-chloro-4-(3-fluorobenzyloxy)aniline | 445-590-4 | 202197-26-0 | - | View substance registered dossier |
| ISOCHEM | 32 rue Lavoisier 91710 VERT LE PETIT France | France | Active | 3-chloro-5-trifluoromethyl-2-pyridylamine | 401-670-0 | 79456-26-1 | - | View substance registered dossier |
| ISOCHEM | 32 rue Lavoisier 91710 VERT LE PETIT France | France | Active | 3-chloropropyl chloroformiate | 425-770-9 | 628-11-5 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 3-cyano-N-(1,1-dimethylethyl)androsta-3,5-diene-17-β-carboxamide | 415-730-9 | 151338-11-3 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | 3-cyanopropyldimethoxymethylsilan | 418-740-1 | 153723-40-1 | - | View substance registered dossier |
| - | - | - | - | 3-Cyclohexyl-2-cyclohexylimino-5-(4-diethylamino-2-methoxyphenyl)methylenoxazolidine-4-one | 457-890-2 | - | - | View substance registered dossier |
| IFF Benicarlo, S.L. | Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain | Spain | Active | 3-Decen-5-one, 4-methyl-, (3E)- | 477-870-7 | 811412-48-3 | 2017 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | 3-dodecyl-(1-(1,2,2,6,6-pentamethyl-4-piperidin)-yl)-2,5-pyrrolidindione | 411-920-0 | 106917-30-0 | - | View substance registered dossier |
| - | - | - | - | 3-ethoxy-1,1,1,2,3,4,4,5,5,6,6,6-dodecafluoro-2-(trifluoromethyl)-hexane | 435-790-1 | 297730-93-9 | - | View substance registered dossier |
| Pfizer Ireland Pharmaceuticals | n/a P43 X3336 Ringaskiddy Cork Ireland | Ireland | Active | 3-ethyl 5-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate | 425-820-1 | 88150-42-9 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 3-ethyl 5-methyl 4-(2-chlorophenyl)-1,4-dihydro-2-[2-(1,3-dihydro-1,3-dioxo-(2H)isoindol-2-yl)-ethoxymethyl]-6-methyl-3,5-pyridinedicarboxylate | 413-410-3 | 88150-62-3 | - | View substance registered dossier |
| Krka, d. d., Novo mesto | Smarjeska cesta 6 SI-8501 Novo mesto Slovenia | Slovenia | Active | 3-ethyl 5-methyl 4-(2-chlorophenyl)-1,4-dihydro-2-[2-(1,3-dihydro-1,3-dioxo-(2H)isoindol-2-yl)-ethoxymethyl]-6-methyl-3,5-pyridinedicarboxylate | 413-410-3 | 88150-62-3 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. | - | - | Active | 3-ethyl 5-methyl 4-(2-chlorophenyl)-1,4-dihydro-2-[2-(1,3-dihydro-1,3-dioxo-(2H)isoindol-2-yl)-ethoxymethyl]-6-methyl-3,5-pyridinedicarboxylate | 413-410-3 | 88150-62-3 | - | View substance registered dossier |
| Borregaard AS | Hjalmar Wessels vei 6 1701 Sarpsborg Norway | Norway | Active | 3-ethyl 5-methyl 4-(2-chlorophenyl)-1,4-dihydro-2-[2-(1,3-dihydro-1,3-dioxo-(2H)isoindol-2-yl)-ethoxymethyl]-6-methyl-3,5-pyridinedicarboxylate | 413-410-3 | 88150-62-3 | - | View substance registered dossier |
| Pfizer Ireland Pharmaceuticals | n/a P43 X3336 Ringaskiddy Cork Ireland | Ireland | Active | 3-ethyl 5-methyl 4-(2-chlorophenyl)-1,4-dihydro-2-[2-(1,3-dihydro-1,3-dioxo-(2H)isoindol-2-yl)-ethoxymethyl]-6-methyl-3,5-pyridinedicarboxylate | 413-410-3 | 88150-62-3 | - | View substance registered dossier |
| ANGUS CHEMIE GMBH | Zeppelinstr. 30 Postfach 4003 D-49479 Ibbenbueren-Uffeln Germany | Germany | Cease Manufacture | 3-ethyl-2-methyl-2-(3-methylbutyl)-1,3-oxazolidine | 421-150-7 | 143860-04-2 | 2013 | View substance registered dossier |
| - | - | - | - | 3-ethyl-2-{[(2Z)-3-ethyl-5-phenyl-2,3-dihydro-1,3-benzoxazol-2-ylidene]methyl}-5-phenyl-1,3-benzoxazol-3-ium; 4-methylbenzene-1-sulfonate | 435-090-4 | 207231-99-0 | - | View substance registered dossier |
| SCAS Europe S.A./N.V. | Leonardo Da Vincilaan 19 B-1831 Diegem Belgium | Belgium | Active | 3-ethyl-3-[(2-ethylhexyloxy)methyl]oxetane | 445-460-7 | - | 2012 | View substance registered dossier |
| - | - | - | - | 3-Fluorphenylboric acid | 476-720-8 | 768-35-4 | - | View substance registered dossier |
| - | - | - | - | 3-heptyl-tetrahydro-pyran | 462-530-2 | 854737-09-0 | - | View substance registered dossier |
| Dow Silicones Belgium SPRL | Rue Jules Bordet Zone industrielle C 7180 Seneffe Belgium | Belgium | Active | 3-hexylheptamethyltrisiloxane | 428-700-5 | 1873-90-1 | - | View substance registered dossier |
| Solenis Belgium B.V.B.A. | Industrieweg 15 3583 Beringen Belgium | Belgium | Cease Manufacture | 3-icosyl-4-henicosylidene-2-oxetanone | 401-210-9 | 83708-14-9 | 2016 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | 3-icosyl-4-henicosylidene-2-oxetanone | 401-210-9 | 83708-14-9 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 3-icosyl-4-henicosylidene-2-oxetanone | 401-210-9 | 83708-14-9 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 3-isopropylidene-1-methylcyclohexene | 404-150-1 | 17092-80-7 | - | View substance registered dossier |
| - | - | - | - | 3-Mercapto-2-methyl-pentan-1-ol | 434-900-3 | 227456-27-1 | - | View substance registered dossier |
| - | - | - | - | 3-MERCAPTOHEXANOL | 440-730-0 | 51755-83-0 | - | View substance registered dossier |
| - | - | - | - | 3-Methoxythiophene | 479-350-5 | 17573-92-1 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 3-methyl-3-(2,2,3,3,3-pentafluoropropoxy)methyl oxetane | 482-280-8 | - | - | View substance registered dossier |
| Central Glass Germany GmbH | Kantstrasse 2 33790 Halle/Westf. Nordrhein Westfalen Germany | Germany | Active | 3-methyl-4-oxo-4-(3-nitro-4-chlorophenyl)butanoic acid | 440-860-8 | - | - | View substance registered dossier |
| - | - | - | - | 3-methyl-5-phenylpentan-1-al | 433-900-0 | 55066-49-4 | - | View substance registered dossier |
| Penman Consulting bvba 10 | Avenue des Arts 10 1210 Brussels Belgium | Belgium | Active | 3-methyl-5-phenylpentan-1-al | 433-900-0 | 55066-49-4 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. | - | - | Active | 3-methyl-N-(5,8,13,14-tetrahydro-5,8,14-trioxonaphth[2,3-c]acridin-6-yl)benzamide | 442-560-2 | 105043-55-8 | - | View substance registered dossier |
| Huntsman Textile Effects (Germany) GmbH | Rehlinger Str. 1 D-86462 Langweid a.Lech Germany | Germany | Active | 3-methyl-N-(5,8,13,14-tetrahydro-5,8,14-trioxonaphth[2,3-c]acridin-6-yl)benzamide | 442-560-2 | 105043-55-8 | 2010 | View substance registered dossier |
| DyStar Colours Distribution GmbH | Am Prime-Parc 12 65479 Raunheim Germany | - | - | 3-methylaminomethylphenylamine | 414-570-7 | 18759-96-1 | - | View substance registered dossier |
| - | - | - | - | 3-methylaminomethylphenylamine | 414-570-7 | 18759-96-1 | - | View substance registered dossier |
| DyStar Colours Distribution GmbH | Am Prime-Parc 12 65479 Raunheim Germany | Germany | Cease Manufacture | 3-N,N-bis(methoxyethyl)aminoacetanilide | 432-530-7 | 24294-01-7 | 2012 | View substance registered dossier |
| Lanxess Deutschland GmbH | Kennedyplatz 1 50569 Köln Germany | - | - | 3-Nitrophthalonitrile | 450-650-8 | 51762-67-5 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. | - | - | Active | 3-oxo-4-aza-5α-androstane-17β-carboxylic acid | 407-820-1 | 103335-55-3 | - | View substance registered dossier |
| Thermofisher Scientific Cork Ltd. | Currabinny P43 AY66 Carrigaline Co. Cork Ireland | - | - | 3-oxo-4-azaandrost-5-ene-17β-carboxylic acid | 407-830-6 | 103335-54-2 | - | View substance registered dossier |
| Glaxo Operations UK | Glaxo Wellcome House Berkeley Avenue UB6 0NN Greenford Middlesex United Kingdom | - | - | 3-oxo-4-azaandrost-5-ene-17β-carboxylic acid | 407-830-6 | 103335-54-2 | - | View substance registered dossier |
| - | - | - | - | 3-oxo-4-azaandrost-5-ene-17β-carboxylic acid | 407-830-6 | 103335-54-2 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 3-oxoandrost-4-ene-17β-carboxylic acid | 414-990-0 | 302-97-6 | - | View substance registered dossier |
| NOVEAL | 16 rue Maurice Berteaux 95500 LE THILLAY France | France | Active | 3-oxyde-2,4-pyrimidinediamine monohydrate | 419-140-2 | - | 2010 | View substance registered dossier |
| [Confidential] | - | - | - | 3-oxyde-2,4-pyrimidinediamine monohydrate | 419-140-2 | - | - | View substance registered dossier |
| Mitsui Chemicals Europe GmbH | Oststr. 34 40211 Dusseldorf Germany | Germany | Active | 3-phenoxybenzyl-2-(4-ethoxyphenyl)-2-methylpropyl ether | 407-980-2 | 80844-07-1 | - | View substance registered dossier |
| Knoell NL_OR_056 | Agro Business Park 75 6708 PV Wageningen Netherlands | Netherlands | Active | 3-phenyl-7-[4-(tetrahydrofurfuryloxy)phenyl]-1,5-dioxa-s-indacen-2,6-dione | 413-330-9 | 134724-55-3 | 2009; 2010; 2012 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. | - | - | Active | 3-phenyl-7-[4-(tetrahydrofurfuryloxy)phenyl]-1,5-dioxa-s-indacen-2,6-dione | 413-330-9 | 134724-55-3 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | 3-phenyl-7-[4-(tetrahydrofurfuryloxy)phenyl]-1,5-dioxa-s-indacen-2,6-dione | 413-330-9 | 134724-55-3 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | 3-phenylpropyldimethoxymethylsilan | 418-750-6 | - | - | View substance registered dossier |
| FUJIFILM Belgium NV | Europark Noord 21-22 9100 Sint-Niklaas Belgium | Belgium | Active | 3-sulfinobenzoic acid | 416-000-2 | - | 2011 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 3-sulfinobenzoic acid | 416-000-2 | - | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 3-tridecyloxy-propyl-ammonium 9-octadecenoate | 418-990-1 | 778577-53-0 | - | View substance registered dossier |
| Archroma Italy, S.r.l. | Via Manzoni 37 20030 Palazzolo Milanese Italy | Italy | Cease Manufacture | 3-{5-[3-(4-{1-[3-(dimethylammonio)propyl]-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo}benzamido)phenylazo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-pyridyl}propyl(dimethyl)ammonium di(acetate); 3-{5-[4-(3-{1,6-dihydro-2-hydroxy-4-methyl-1-[3-(methylammonio)propyl]-6-oxo-3-pyridylazo}benzamido]phenylazo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-pyridyl}propyl(dimethyl)ammonium di(acetate); reaction mass of: 3-{5-[3-(4-{1,6-dihydro-2-hydroxy-4-methyl-1-[3-(methylammonio)propyl]-6-oxo-3-pyridylazo}benzamido)phenylazo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-pyridyl}propyl(methyl)ammonium di(acetate) | 431-440-5 | - | 2017 | View substance registered dossier |
| Archroma Italy, S.r.l. - OR | Via Manzoni 37 20030 Palazzolo Milanese Italy | Italy | Cease Manufacture | 3-{5-[3-(4-{1-[3-(dimethylammonio)propyl]-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo}benzamido)phenylazo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-pyridyl}propyl(dimethyl)ammonium di(acetate); 3-{5-[4-(3-{1,6-dihydro-2-hydroxy-4-methyl-1-[3-(methylammonio)propyl]-6-oxo-3-pyridylazo}benzamido]phenylazo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-pyridyl}propyl(dimethyl)ammonium di(acetate); reaction mass of: 3-{5-[3-(4-{1,6-dihydro-2-hydroxy-4-methyl-1-[3-(methylammonio)propyl]-6-oxo-3-pyridylazo}benzamido)phenylazo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-pyridyl}propyl(methyl)ammonium di(acetate) | 431-440-5 | - | 2017 | View substance registered dossier |
| Archroma Italy, S.r.l. - OR | Via Manzoni 37 20030 Palazzolo Milanese Italy | - | - | 3-{[3-Acetylamino-4-(2-cyano-4,6-dinitro-phenylazo)-phenyl]-ethyl-amino}-propionic acid 2-oxo-2-phenyl-ethyl ester | 454-440-7 | 682809-44-5 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. | - | - | Active | 327 QRN | 424-580-3 | - | - | View substance registered dossier |
| - | - | - | - | 327 QRN | 424-580-3 | - | - | View substance registered dossier |
| BASF Coatings GmbH | Glasuritstrasse 1 Postfach 6123 48136 Münster Nordrhein-Westfalen Germany | Germany | Cease Manufacture | 350CD0001 | 436-940-7 | - | 2018 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 3940W92 | 425-610-8 | - | - | View substance registered dossier |
| Merck Performance Materials GmbH | Rheingaustrasse 190-196 65203 Wiesbaden Germany | - | - | 3G3 RESIN | 443-110-8 | - | - | View substance registered dossier |
| 3M Belgium BVBA/SPRL | Hermeslaan 7 1831 Diegem Belgium | Belgium | Active | 3M (TM) SPECIALTY GAS PFG-3480 | 440-180-1 | - | 2011 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. | - | - | Active | 3M (TM) SPECIALTY GAS PFG-3480 | 440-180-1 | - | - | View substance registered dossier |
| Boehringer Ingelheim Pharma GmbH & Co. KG | Binger Strasse 173 55216 Ingelheim am Rhein Germany | - | - | 4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile | 480-420-2 | - | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 4'-methyldodecane-1-sulfonanilide | 435-490-9 | 17417-32-2 | - | View substance registered dossier |
| Kodak Alaris Germany GmbH | Augsburger Str. 712 70329 Stuttgart Germany | Germany | Cease Manufacture | 4'-methyldodecane-1-sulfonanilide | 435-490-9 | 17417-32-2 | 2019 | View substance registered dossier |
| Merck KGaA | Frankfurter Strasse 250 64293 Darmstadt Germany | Germany | Active | 4'-trans-ethyl-[1,1'-bicyclohexyl]-4-one | 485-460-4 | - | 2019 | View substance registered dossier |
| BASF Grenzach GmbH | Köchlinstr. 1 79639 Grenzach-Wyhlen Germany | Germany | Active | 4,4'(4-(4-methoxyphenyl)-1,3,5-triazin-2,4-diyl)bisbenzene-1,3-diol | 444-500-0 | 1440-00-2 | 2011 | View substance registered dossier |
| AllessaProduktion GmbH | Alt-Fechenheim 34 60386 Frankfurt am Main Germany | Germany | Cease Manufacture | 4,4'(4-(4-methoxyphenyl)-1,3,5-triazin-2,4-diyl)bisbenzene-1,3-diol | 444-500-0 | 1440-00-2 | 2014 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. | - | - | Active | 4,4',4''-(1-methylpropan-1-yl-3-ylidene)tris(2-cyclohexyl-5-methylphenol) | 407-460-5 | 111850-25-0 | - | View substance registered dossier |
| ADEKA Europe GmbH | Berliner Allee 22 40212 Düsseldorf Germany | Germany | Active | 4,4',4''-(1-methylpropan-1-yl-3-ylidene)tris(2-cyclohexyl-5-methylphenol) | 407-460-5 | 111850-25-0 | 2012 | View substance registered dossier |
| Merck Performance Materials GmbH | Rheingaustrasse 190-196 65203 Wiesbaden Germany | Germany | Cease Manufacture | 4,4',4''-(ethan-1,1,1-triyl)triphenol | 405-800-7 | 27955-94-8 | 2019 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. | - | - | Active | 4,4',4''-(ethan-1,1,1-triyl)triphenol | 405-800-7 | 27955-94-8 | - | View substance registered dossier |
| Lanxess Deutschland GmbH | Kennedyplatz 1 50569 Köln Germany | Germany | Active | 4,4',4''-(ethan-1,1,1-triyl)triphenol | 405-800-7 | 27955-94-8 | 2011; 2012; 2013 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 4,4',4''-(ethan-1,1,1-triyl)triphenol | 405-800-7 | 27955-94-8 | - | View substance registered dossier |
| Clariant Produkte (Deutschland) GmbH | Am Unisys-Park 1 65843 Sulzbach am Taunus Germany | Germany | Active | 4,4',5,5',6,6',7,7'-octachloro-(2,2')biisoindolyl-1,1',3,3'-tetraone | 429-150-9 | 67887-47-2 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | 4,4'-(1,3-phenylene-bis(1-methylethylidene))bis-phenol | 428-970-4 | 13595-25-0 | - | View substance registered dossier |
| - | - | - | - | 4,4'-(1-{4-[1-(4-hydroxyphenyl)-1-methylethyl]phenyl}ethylidene)diphenol | 425-600-3 | 110726-28-8 | - | View substance registered dossier |
| JSR Micro n.v. | Technologielaan 8 3001 Leuven Belgium | - | - | 4,4'-(1-{4-[1-(4-hydroxyphenyl)-1-methylethyl]phenyl}ethylidene)diphenol | 425-600-3 | 110726-28-8 | - | View substance registered dossier |
| Covance Clinical Development SA 151 | Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain | - | - | 4,4'-(1-{4-[1-(4-hydroxyphenyl)-1-methylethyl]phenyl}ethylidene)diphenol | 425-600-3 | 110726-28-8 | - | View substance registered dossier |
| Cytec Industries BV | Burgemeester van Lierplein 75 3134 ZB Vlaardingen Netherlands | Netherlands | Cease Manufacture | 4,4'-(9H-fluoren-9-ylidene)bis(2-chloroaniline) | 407-560-9 | 107934-68-9 | 2020 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. | - | - | Active | 4,4'-(9H-fluoren-9-ylidene)bis(2-chloroaniline) | 407-560-9 | 107934-68-9 | - | View substance registered dossier |
| Evonik Operations GmbH | Rellinghauser Straße 1-11 45128 Essen Germany | - | - | 4,4'-(oxy-(bismethylene))-bis-1,3-dioxolane | 423-230-7 | 56552-15-9 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. | - | - | Active | 4,4'-[(1,10-dioxodecane-1,10-diyl)bis(oxy)]bis(2,2,6,6-tetramethylpiperidine-1-oxidanyl) | 417-440-8 | 2516-92-9 | - | View substance registered dossier |
| - | - | - | - | 4,4'-bis(2-methyl-2-(4-methylphenyl)-1-propionyl)diphenylsulfide | 415-410-9 | - | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | 4,4'-bis(N-carbamoyl-4-methylbenzensulfonamide)diphenylmethane | 418-770-5 | 151882-81-4 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. | - | - | Active | 4,4'-carbonylbis[2-({[3-(triethoxysilyl)propyl]amino}carbonyl)benzoic acid] | 419-190-5 | - | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. | - | - | Active | 4,4'-dithiobis(5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-1H-pyrazole-3-carbonitrile) | 423-490-1 | 130755-46-3 | - | View substance registered dossier |
| Huntsman Advanced Materials (Europe) BV | Everslaan 45 B-3078 Everberg Belgium | Belgium | Active | 4,4'-ethylidenediphenyl dicyanate | 405-740-1 | 47073-92-7 | 2010 | View substance registered dossier |
| Lonza Biologics PLC | The Courtyard, Severn Drive GL20 8GD Tewkesbury Gloucestershire United Kingdom | United Kingdom | No longer Valid | 4,4'-methylene bis(3-chloro-2,6-di-ethylphenylisocyanate) | 420-530-1 | - | 2021 | View substance registered dossier |
| Huntsman Advanced Materials (Europe) BV | Everslaan 45 B-3078 Everberg Belgium | Belgium | Active | 4,4'-methylenebis(2,6-dimethylphenyl cyanate) | 405-790-4 | 101657-77-6 | 2010 | View substance registered dossier |
| Lonza Cologne GmbH - REACH | Nattermannallee 1 50829 Cologne Germany | Germany | Active | 4,4'-methylenebis(2-isopropyl-6-methylaniline) | 415-150-6 | 16298-38-7 | 2010 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. | - | - | Active | 4,4'-methylenebis(2-isopropyl-6-methylaniline) | 415-150-6 | 16298-38-7 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 4,4'-methylenebis[N-(4-chlorophenyl)-3-hydroxynaphthalene-2-carboxamide] | 430-350-3 | 192463-88-0 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | 4,4'-oxybis(ethylenethio)diphenol | 404-590-4 | 90884-29-0 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. | - | - | Active | 4,4'-oxybis(ethylenethio)diphenol | 404-590-4 | 90884-29-0 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 4,4'-oxydiphthalic anhydride | 412-830-4 | 1823-59-2 | - | View substance registered dossier |
| Charles River Laboratories Den Bosch B.V. OR19 | Hambakenwetering 7 5231 DD 's-Hertogenbosch Netherlands | Netherlands | Active | 4,4'-sulfonylbisphenol, polymer with ammonium chloride(NH4Cl), pentachlorophosphorane and phenol | 439-270-3 | 260408-02-4 | 2015; 2016 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 4,4'-thiodi-o-cresol | 403-330-7 | 24197-34-0 | - | View substance registered dossier |
| Tessenderlo Group N.V. | Troonstraat 130 BE-1050 Brussel Belgium | Belgium | Cease Manufacture | 4,4,5,5,-tetrachloro-1,3-dioxolan-2-one | 404-060-2 | 22432-68-4 | 2017 | View substance registered dossier |
| AstraZeneca | Alderley Park AZ SHE Chemical Registration SK10 4TF Macclesfield Cheshire United Kingdom | United Kingdom | Cease Manufacture | 4,4,5,5,5-pentafluoropentan-1-ol | 421-360-9 | 148043-73-6 | 2017 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 4,4-dimethoxybutylamine | 407-690-6 | 19060-15-2 | - | View substance registered dossier |
| Lonza Cologne GmbH | Nattermannallee 1 50829 Cologne Germany | Germany | No longer Valid | 4,4-methylenebis-3-(chloro-2,6-diethyl)-aniline | 402-130-7 | 106246-33-7 | 2010 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. | - | - | Active | 4,4-methylenebis-3-(chloro-2,6-diethyl)-aniline | 402-130-7 | 106246-33-7 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 4,4-methylenebis-3-(chloro-2,6-diethyl)-aniline | 402-130-7 | 106246-33-7 | - | View substance registered dossier |
| Lonza Cologne GmbH - REACH | Nattermannallee 1 50829 Cologne Germany | Germany | Active | 4,4-methylenebis-3-(chloro-2,6-diethyl)-aniline | 402-130-7 | 106246-33-7 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. | - | - | Active | 4,4-methylenebis-3-(chloro-2,6-diethyl)-aniline | 402-130-7 | 106246-33-7 | - | View substance registered dossier |
| - | - | - | - | 4,4-Methylenediphenylene-bis(dimethylurea) | 423-370-9 | 10097-09-3 | - | View substance registered dossier |
| Huntsman Advanced Materials (Europe) BV OR-USA | Everslaan 45 B-3078 Everberg Belgium | Belgium | Active | 4,4-Methylenediphenylene-bis(dimethylurea) | 423-370-9 | 10097-09-3 | - | View substance registered dossier |
| ARKEMA FRANCE | 420 rue d'Estienne d'Orves 92700 COLOMBES France | - | - | 4,5-di-tert-butyl-6-ethoxy-2,2-dimethyl-3,7-dioxa-4-aza-6-phosphanonan-1-oic acid 6-oxide | 449-920-8 | - | - | View substance registered dossier |
| - | - | - | - | 4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol | 443-400-4 | - | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Danish competent national authority. | - | - | Active | 4,6-bis(octylthiomethyl)-o-cresol | 402-860-6 | 110553-27-0 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. | - | - | Active | 4,6-bis(octylthiomethyl)-o-cresol | 402-860-6 | 110553-27-0 | - | View substance registered dossier |
| - | - | - | - | 4,6-bis[(4-hydroxy-3,5-dimethylphenyl)methyl]-1,2,3-benzenetriol, mixed with 6-diazo-5,6-dihydro-5-oxonaphthalene-1-sulfonic acid | 451-140-8 | 133686-87-0 | - | View substance registered dossier |
| Covance Clinical Development SA 151 | Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain | Spain | Active | 4,6-bis[2-(4-hydroxyphenyl)isopropylidene]resorcinol | 432-380-2 | 147504-92-5 | 2011 | View substance registered dossier |
| - | - | - | - | 4,6-bis[2-(4-hydroxyphenyl)isopropylidene]resorcinol | 432-380-2 | 147504-92-5 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | 4,7-methanooctahydro-1H-indene-diyldimethyl bis(2-carboxybenzoate) | 407-410-2 | - | - | View substance registered dossier |
| INEOS Styrolution Köln GmbH | Alte Str. 201 50769 Köln NRW Germany | Germany | Active | 4,7-methanooctahydro-1H-indene-diyldimethyl bis(2-carboxybenzoate) | 407-410-2 | - | 2011 | View substance registered dossier |
| - | - | - | - | 4,7-Octadienoic acid, methyl ester, (4E)- | 422-840-0 | 189440-77-5 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 4,7-Octadienoic acid, methyl ester, (4E)- | 422-840-0 | 189440-77-5 | - | View substance registered dossier |
| Charles River Laboratories Den Bosch B.V. OR06 | Hambakenwetering 7 5231DD 's-Hertogenbosch Netherlands | Netherlands | Active | 4,8-bis(mercaptomethyl)-3,6,9-trithia-1,11-undecanedithiol; 5,7-bis(mercaptomethyl)-3,6,9-trithia-1,11-undecanedithiol; reaction mass of: 4,7-bis(mercaptomethyl)-3,6,9-trithia-1,11-undecanedithiol | 427-050-1 | 170016-25-8 | 2010; 2012; 2013; 2014 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. | - | - | Active | 4-((4-(diethylamino)-2-ethoxyphenyl)imino)-1,4-dihydro-1-oxo-N-propyl-2-naphthalenecarboxamide | 412-650-6 | 121487-83-0 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 4-((4-(diethylamino)-2-ethoxyphenyl)imino)-1,4-dihydro-1-oxo-N-propyl-2-naphthalenecarboxamide | 412-650-6 | 121487-83-0 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. | - | - | Active | 4-(1,4-dioxa-spiro[4.5]dec-8-yl)-cyclohexanone | 423-860-2 | 56309-94-5 | - | View substance registered dossier |
| Evonik Operations GmbH | Rellinghauser Straße 1-11 45128 Essen Germany | Germany | Cease Manufacture | 4-(1,4-dioxa-spiro[4.5]dec-8-yl)-cyclohexanone | 423-860-2 | 56309-94-5 | 2019 | View substance registered dossier |
| CU Chemie Uetikon GmbH | Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany | Germany | Active | 4-(1,4-dioxa-spiro[4.5]dec-8-yl)-cyclohexanone | 423-860-2 | 56309-94-5 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | 4-(1-oxo-2-propenyl)-morpholine | 418-140-1 | 5117-12-4 | - | View substance registered dossier |
| IVICT Europe GmbH | Kennedydamm 19 40476 Düsseldorf Germany | Germany | Active | 4-(1-oxo-2-propenyl)-morpholine | 418-140-1 | 5117-12-4 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 4-(2,2-diphenylethenyl)-N,N-di-phenylbenzenamine | 421-390-2 | 89114-90-9 | - | View substance registered dossier |
| FujiFilm Manufacturing Europe BV | Oudenstaart 1 5047 TK Tilburg Netherlands | Netherlands | Cease Manufacture | 4-(2-carboxymethylthio)ethoxy-1-hydroxy-5-isobutyloxycarbonylamino-N-(3-dodecyloxypropyl)-2-naphthamide | 420-730-7 | - | 2019 | View substance registered dossier |
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