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Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The REACH Registered substance portal was updated on 9th November 2020; the REACH registered factsheets were further updated on 21st December 2020. Details of the improvements can be found at Dissemination Platform Updates. Reprocessing the entire dataset is ongoing since 21 December 2020. ECHA is making all possible efforts to make the improvements and additional data visible with the shortest delay.
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
Last updated 07 March 2021. Database contains 23184 unique substances and contains information from 93714 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
Select total tonnage band range:

0

Infinite



Uses and exposure
Life cycle:
  • Consumer Uses
  • Article service life
  • Widespread uses by professional workers
  • Formulation or re-packing
  • Uses at industrial sites
  • Manufacture
Category:
Details
((2-ethyl-1-oxohexyl)oxy)-(1-phenyl-1,3-decanedionyl)dioctyl stannane; bis(1-phenyl-1,3-decanedionyl)dioctyl stannane; bis[((2-ethyl-1-oxohexyl)oxy)dioctylstannyl]oxide; reaction mass of: bis[(2-ethyl-1-oxohexyl)oxy]dioctyl stannane
422-920-5 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
((6-chloro-4-((2-methoxy-3-(1-methyl-1H-1.2.4-triazol-3-yl)phenyl)amino)pyridazine-3-carbonyl)oxy) hemi-zinc salt
950-319-2 - Active Intermediate Individual Intermediate use only 10-07-2019 View substance registered dossier
(+)-13-ethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione
418-490-3 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(+)-trans-3,3-dimethyl-5-(2,2,3-trimethyl-cyclopent-3-en-1-yl)pent-4-en-2-ol
944-817-9 - null Full Joint 10 - 100 tonnes per annum 03-07-2020 View substance registered dossier
(+-)-(3aRS,5aSR,9aSR,9bSR)-3a,6,6,9a-Tetramethyldodecahydronaphtho[2,1-b]furan
948-069-4 - Active Full Joint ≥ 1 to < 10 tonnes 31-05-2018 View substance registered dossier
(+-)-3-(2-chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2- methyl-4H-pyrido[1,2-a]pyrimidin-4-one
451-680-4 - Active NONS Joint Tonnage data confidential 08-08-2017 View substance registered dossier
(+/-)-(R*,R*)-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran; 6-fluoro-2-(2-oxiranyl)chromane
419-620-1 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(+/-)-1-[4-Chloro-2-(1-hydroxy-1-phenylethyl)phenyl]-3-ethylthiourea
924-673-3 - Active Intermediate Individual Intermediate use only 28-04-2016 View substance registered dossier
(+/-)-2,3-dihydro-2-hydroxy-3,3-dimethylbenzofuran-5-ylethanesulfonate
402-720-4 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
(+/-)-2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-1-ol
413-570-4 - Active NONS Joint Tonnage data confidential 14-06-2011 View substance registered dossier
(+/-)-cis-3-acetoxy-4-phenylazetidine-2-one
425-840-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(+/-)-α-[(2-acetyl-5-methylphenyl)-amino]-2,6-dichlorobenzene-aceto-nitrile
419-290-9 - Active NONS Joint Tonnage data confidential 17-08-2010 View substance registered dossier
(1,1'-bis(diphenylphosphino)ferrocene)dichloropalladium
460-040-3 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(1,5 CYCLOOCTADIEN)RUTHENIUM(II) CHLORID POLYMER
442-400-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(1,5-cyclooctadiene)(2,4-pentanedionato)rhodium(I)
456-980-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(1-3)PEPTIDE
427-530-9 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(1-[2-[5-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]ACETYL]-4-HETEROMONOCYCLECARBOTHIOAMIDE)
- - Active Full Individual ≥ 100 to < 1 000 tonnes 10-07-2017 View substance registered dossier
(1-ethoxyethoxy)cyclododecane
446-240-3 - Active Full Joint ≥ 1 to < 10 tonnes 05-05-2020 View substance registered dossier
(1-ethoxyethoxy)cyclododecane
446-240-3 - Active NONS Joint Tonnage data confidential 22-11-2012 View substance registered dossier
(1-naphthylmethyl)(tetrahydrofuran-2-ylmethyl)malonic acid hydrate (1:1)
700-583-8 - Active Intermediate Joint Intermediate use only 08-05-2017 View substance registered dossier
(17β)-3-oxoestra-4,6-dien-17-yl acetate
425-330-6 - Active NONS Individual Tonnage data confidential 26-01-2011 View substance registered dossier
(17β)-3-{[alkyl(dimethyl)silyl]substituted}-17-[(trimethylsilyl)substitued]estratetraene
- - Active Intermediate Joint Intermediate use only 21-01-2021 View substance registered dossier
(17β)-3-{[alkyl(dimethyl)silyl]substituted}estratetraen-17-ol
- - Active Intermediate Joint Intermediate use only 06-11-2020 View substance registered dossier
(1aR,5S,8S,10R,22aR)·5 tert·butyl-14·methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a tetradecahydro-8H-7,10·methanocyclopropa(18,19)(1,10,3,6)dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid
943-551-0 - Active Intermediate Joint Intermediate use only 24-05-2017 View substance registered dossier
(1R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolinium (2S)-2-(6-methoxy-2-naphthyl)propanoate
941-846-9 - Active Intermediate Individual Intermediate use only 17-03-2015 View substance registered dossier
(1R,2R)-1,3-Dihydroxy-1-(4-nitrophenyl)propyl-2-ammonium (1R, 5S)-5-(dimethylphenylsilyl)-2-(hydroxymethyl)cyclopent-2-ene-1-carboxylate
445-910-2 - Active Full Joint ≥ 1 to < 10 tonnes 14-10-2016 View substance registered dossier
(1R,2R)-1-amino-2-difluoromethyl)-N- (1-methylcyclopropylsulfonyl)cyclo propanecarboxyamide hydrochloride
943-460-6 - null Intermediate Joint Intermediate Use Only 26-06-2020 View substance registered dossier
(1R,2S)-2,6-dimethyl-2,3-dihydro-1H-inden-1-amine
700-140-9 - Active Intermediate Joint Intermediate use only 19-02-2020 View substance registered dossier
(1R,2S)-2,6-dimethyl-2,3-dihydro-1H-inden-1-amine
700-140-9 - Active Intermediate Individual Intermediate use only 18-05-2011 View substance registered dossier
(1R,2S,2'S,4R)-1,7,7-Trimethylbicyclo (2.2.1)heptane-2-spiro-4'-(2'-isopropyl-1',3'-dioxane)
443-460-1 - Active Full Joint ≥ 1 tonnes 05-07-2012 View substance registered dossier
(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
939-499-3 - Active Intermediate Individual Intermediate use only 24-05-2013 View substance registered dossier
(1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
447-620-1 - Active NONS Joint Tonnage data confidential 07-10-2010 View substance registered dossier
(1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
447-620-1 - Active Intermediate Joint Intermediate use only 13-07-2018 View substance registered dossier
(1R,3S,7R,8R,10R,13R)-5,5,7,9,9,13-hexamethyl-4,6-dioxatetracyclo[6.5.1.01,10.03,7]tetradecane
427-580-1 - Active Full Joint ≥ 10 tonnes 09-07-2020 View substance registered dossier
(1R,4R)-4-methoxy-2,2,7,7-tetramethyltricyclo(6.2.1.0(1,6))undec-5-ene
444-480-3 - Active NONS Individual Tonnage data confidential 07-04-2011 View substance registered dossier
(1R,4S,4aR,8aS)-9-(dichloromethylidene)octahydro-1,4-methanonaphthalene-5,8-dione
700-729-0 - Active Intermediate Joint Intermediate use only 08-12-2020 View substance registered dossier
(1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylic acid
944-682-6 - Active Intermediate Joint Intermediate use only 22-12-2017 View substance registered dossier
(1R,8S)-2,2,7,7-tetramethyltricyclo[6.2.1.0^{1,6}]undec-5-en-4-one
942-035-2 - Active Intermediate Individual Intermediate use only 04-03-2015 View substance registered dossier
(1RS, 2SR) (+/-) Methyl trans 2,6,6,-trimethyl-3-cyclohexene-1-carboxylate
453-570-1 - Active Full Joint ≥ 1 to < 10 tonnes 14-03-2016 View substance registered dossier
(1RS, 2SR) (+/-) Methyl trans 2,6,6,-trimethyl-3-cyclohexene-1-carboxylate
453-570-1 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
(1RS,2RS,3RS,6RS,8SR)-8-methoxytricyclo[5.2.1.0(2,6)]decane-3-carbaldehyde; (1RS,2RS,4SR,6RS,8SR)-8-methoxytricyclo[5.2.1.0(2,6)]decane-4-carbaldehyde; reaction mass of: (1RS,2RS,3SR,6RS,9SR)-9-methoxytricyclo[5.2.1.0(2,6)]decane-3-carbaldehyde
429-860-9 - Active NONS Joint Tonnage data confidential 24-04-2013 View substance registered dossier
(1S)-1,2,3,4-tetrahydro-1-phenylisoquinoline
445-640-5 - Active NONS Individual Tonnage data confidential 25-05-2011 View substance registered dossier
(1S)-1-(3-methoxyphenyl)-N-methylethanamine hydrobromide (1:1)
940-296-7 - Active Full Joint ≥ 1 to < 10 tonnes 11-11-2015 View substance registered dossier
(1S)-1-cyclopropylethanamine; (2R)-2-hydroxy-2-phenyl-acetic acid
946-290-0 - Active Intermediate Joint Intermediate use only 01-10-2020 View substance registered dossier
(1S)-1-NAPHTHYLETHYLAMINE
436-100-1 - Active Intermediate Joint Intermediate use only 20-12-2017 View substance registered dossier
(1S)-1-Phenylethanaminium (2S)-2-(2-fluorobiphenyl-4-yl)propanoate
942-079-2 - No longer Valid Intermediate Individual No longer valid 05-03-2020 View substance registered dossier
(1S,1'R)-[1-(3',3'-dimethyl-1'-cyclohexyl)ethoxycarbonyl]methyl propanoate
431-700-8 - null NONS Individual Tonnage Data Confidential 14-06-2020 View substance registered dossier
(1S,1'R)-[1-(3',3'-dimethyl-1'-cyclohexyl)ethoxycarbonyl]methyl propanoate
431-700-8 - Active Full Joint ≥ 0 tonnes 05-08-2020 View substance registered dossier
(1S,2R)-1-((2R,3R,4S,6S)-3-acetamido-4-(diallylamino)-6-hydroxy-6-(methoxycarbonyl)tetrahydro-2H-pyran-2-yl)propane-1,2,3-triyl triacetate
700-779-3 - Cease Manufacture Intermediate Individual Cease manufacture 31-05-2012 View substance registered dossier
(1S,2S,5S)-2-(2-chloroethyl)-6,6-dimethylbicyclo[3.1.1]heptane
700-524-6 - null Intermediate Joint Intermediate Use Only 13-06-2020 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
ELKEM SILICONES FRANCE S.A.S. Immeuble DANICA 21, Avenue Georges Pompidou 69003 Lyon France France Active ((2-ethyl-1-oxohexyl)oxy)-(1-phenyl-1,3-decanedionyl)dioctyl stannane; bis(1-phenyl-1,3-decanedionyl)dioctyl stannane; bis[((2-ethyl-1-oxohexyl)oxy)dioctylstannyl]oxide; reaction mass of: bis[(2-ethyl-1-oxohexyl)oxy]dioctyl stannane 422-920-5 - - View substance registered dossier
SK BIOTEK IRELAND LIMITED Watery Lane Swords K67 AY91 Swords Co. Dublin Ireland Ireland Active ((6-chloro-4-((2-methoxy-3-(1-methyl-1H-1.2.4-triazol-3-yl)phenyl)amino)pyridazine-3-carbonyl)oxy) hemi-zinc salt 950-319-2 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (+)-13-ethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione 418-490-3 - - View substance registered dossier
[Confidential] [Confidential] - - (+)-trans-3,3-dimethyl-5-(2,2,3-trimethyl-cyclopent-3-en-1-yl)pent-4-en-2-ol 944-817-9 - - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France - - (+)-trans-3,3-dimethyl-5-(2,2,3-trimethyl-cyclopent-3-en-1-yl)pent-4-en-2-ol 944-817-9 - - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (+-)-(3aRS,5aSR,9aSR,9bSR)-3a,6,6,9a-Tetramethyldodecahydronaphtho[2,1-b]furan 948-069-4 - - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (+-)-3-(2-chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2- methyl-4H-pyrido[1,2-a]pyrimidin-4-one 451-680-4 - 2010; 2013; 2017 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (+/-)-(R*,R*)-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran; 6-fluoro-2-(2-oxiranyl)chromane 419-620-1 - 2017 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active (+/-)-(R*,R*)-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran; 6-fluoro-2-(2-oxiranyl)chromane 419-620-1 - - View substance registered dossier
EXPANSIA Route d'Avignon BP 6 30390 ARAMON France France Active (+/-)-1-[4-Chloro-2-(1-hydroxy-1-phenylethyl)phenyl]-3-ethylthiourea 924-673-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (+/-)-2,3-dihydro-2-hydroxy-3,3-dimethylbenzofuran-5-ylethanesulfonate 402-720-4 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active (+/-)-2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-1-ol 413-570-4 - - View substance registered dossier
ISAGRO SpA via Caldera 21 20153 Milan Italy Italy Active (+/-)-2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-1-ol 413-570-4 - 2011 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active (+/-)-2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-1-ol 413-570-4 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (+/-)-2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-1-ol 413-570-4 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (+/-)-cis-3-acetoxy-4-phenylazetidine-2-one 425-840-9 - - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (+/-)-α-[(2-acetyl-5-methylphenyl)-amino]-2,6-dichlorobenzene-aceto-nitrile 419-290-9 - 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active (+/-)-α-[(2-acetyl-5-methylphenyl)-amino]-2,6-dichlorobenzene-aceto-nitrile 419-290-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (1,1'-bis(diphenylphosphino)ferrocene)dichloropalladium 460-040-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (1,5 CYCLOOCTADIEN)RUTHENIUM(II) CHLORID POLYMER 442-400-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (1,5-cyclooctadiene)(2,4-pentanedionato)rhodium(I) 456-980-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active (1-3)PEPTIDE 427-530-9 - - View substance registered dossier
DuPont Solutions (France) SAS Equinoxe 2 1bis avenue du 8 Mai 1945 78280 Guyancour France France Active (1-[2-[5-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]ACETYL]-4-HETEROMONOCYCLECARBOTHIOAMIDE) - - - View substance registered dossier
FIRMENICH GRASSE SAS OR 2 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (1-ethoxyethoxy)cyclododecane 446-240-3 - 2020 View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (1-ethoxyethoxy)cyclododecane 446-240-3 - 2011; 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (1-ethoxyethoxy)cyclododecane 446-240-3 - - View substance registered dossier
Derivados Químicos S.A. Camino Viejo del Pliego s/n 30820 Alcantarilla Murcia Spain Spain Active (1-naphthylmethyl)(tetrahydrofuran-2-ylmethyl)malonic acid hydrate (1:1) 700-583-8 - 2017 View substance registered dossier
Aspen Oss BV Kloosterstraat 6 5349 AB Oss Netherlands Netherlands Active (17β)-3-oxoestra-4,6-dien-17-yl acetate 425-330-6 - 2011 View substance registered dossier
[Confidential] - - - (17β)-3-{[alkyl(dimethyl)silyl]substituted}-17-[(trimethylsilyl)substitued]estratetraene - - - View substance registered dossier
[Confidential] - - - (17β)-3-{[alkyl(dimethyl)silyl]substituted}estratetraen-17-ol - - - View substance registered dossier
MSD International GmbH Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active (1aR,5S,8S,10R,22aR)·5 tert·butyl-14·methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a tetradecahydro-8H-7,10·methanocyclopropa(18,19)(1,10,3,6)dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid 943-551-0 - - View substance registered dossier
RECORDATI SPA Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy Italy Active (1R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolinium (2S)-2-(6-methoxy-2-naphthyl)propanoate 941-846-9 - - View substance registered dossier
Swords Laboratories Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland Ireland Active (1R,2R)-1,3-Dihydroxy-1-(4-nitrophenyl)propyl-2-ammonium (1R, 5S)-5-(dimethylphenylsilyl)-2-(hydroxymethyl)cyclopent-2-ene-1-carboxylate 445-910-2 - 2010; 2012; 2014; 2016 View substance registered dossier
Hovione FarmaCiencia SA Sete Casas 2674-506 Loures Portugal Portugal Active (1R,2R)-1,3-Dihydroxy-1-(4-nitrophenyl)propyl-2-ammonium (1R, 5S)-5-(dimethylphenylsilyl)-2-(hydroxymethyl)cyclopent-2-ene-1-carboxylate 445-910-2 - 2010; 2011; 2012; 2014 View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy - - (1R,2R)-1-amino-2-difluoromethyl)-N- (1-methylcyclopropylsulfonyl)cyclo propanecarboxyamide hydrochloride 943-460-6 - - View substance registered dossier
AbbVie Ireland NL B.V. Manorhamilton Road none Sligo Ireland - - (1R,2R)-1-amino-2-difluoromethyl)-N- (1-methylcyclopropylsulfonyl)cyclo propanecarboxyamide hydrochloride 943-460-6 - - View substance registered dossier
AbbVie Logistics B.V. Zuiderzeelaan 53 8017 JV Zwolle Netherlands - - (1R,2R)-1-amino-2-difluoromethyl)-N- (1-methylcyclopropylsulfonyl)cyclo propanecarboxyamide hydrochloride 943-460-6 - - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (1R,2S)-2,6-dimethyl-2,3-dihydro-1H-inden-1-amine 700-140-9 - 2011; 2019; 2020 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active (1R,2S)-2,6-dimethyl-2,3-dihydro-1H-inden-1-amine 700-140-9 - 2011 View substance registered dossier
Givaudan France SAS - OR1 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France France Active (1R,2S,2'S,4R)-1,7,7-Trimethylbicyclo (2.2.1)heptane-2-spiro-4'-(2'-isopropyl-1',3'-dioxane) 443-460-1 - 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (1R,2S,2'S,4R)-1,7,7-Trimethylbicyclo (2.2.1)heptane-2-spiro-4'-(2'-isopropyl-1',3'-dioxane) 443-460-1 - - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active (1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate 939-499-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - - View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - 2010 View substance registered dossier
- - - - (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - 2018 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - - View substance registered dossier
Symrise Ltd. Fieldhouse Lane SL7 1TB Marlow Bucks Buckinghamshire United Kingdom United Kingdom Active (1R,3S,7R,8R,10R,13R)-5,5,7,9,9,13-hexamethyl-4,6-dioxatetracyclo[6.5.1.01,10.03,7]tetradecane 427-580-1 - 2016 View substance registered dossier
Symrise Ibérica, S.L. Polígono Industrial Can Volart Ctra. C-17 Km. 15 08150 Parets de Valles (Barcelona) Spain Spain Active (1R,3S,7R,8R,10R,13R)-5,5,7,9,9,13-hexamethyl-4,6-dioxatetracyclo[6.5.1.01,10.03,7]tetradecane 427-580-1 - 2019 View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (1R,3S,7R,8R,10R,13R)-5,5,7,9,9,13-hexamethyl-4,6-dioxatetracyclo[6.5.1.01,10.03,7]tetradecane 427-580-1 - 2010; 2015 View substance registered dossier
Symrise A4 Mühlenfeldstr. 1 37603 Holzminden Germany Germany Active (1R,3S,7R,8R,10R,13R)-5,5,7,9,9,13-hexamethyl-4,6-dioxatetracyclo[6.5.1.01,10.03,7]tetradecane 427-580-1 - 2019 View substance registered dossier
[Confidential] - - - (1R,3S,7R,8R,10R,13R)-5,5,7,9,9,13-hexamethyl-4,6-dioxatetracyclo[6.5.1.01,10.03,7]tetradecane 427-580-1 - - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (1R,3S,7R,8R,10R,13R)-5,5,7,9,9,13-hexamethyl-4,6-dioxatetracyclo[6.5.1.01,10.03,7]tetradecane 427-580-1 - - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (1R,4R)-4-methoxy-2,2,7,7-tetramethyltricyclo(6.2.1.0(1,6))undec-5-ene 444-480-3 - 2011 View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa - Attiki Greece Greece Active (1R,4S,4aR,8aS)-9-(dichloromethylidene)octahydro-1,4-methanonaphthalene-5,8-dione 700-729-0 - 2019 View substance registered dossier
Syngenta Ltd Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom United Kingdom Active (1R,4S,4aR,8aS)-9-(dichloromethylidene)octahydro-1,4-methanonaphthalene-5,8-dione 700-729-0 - 2020 View substance registered dossier
[Confidential] - - - (1R,4S,4aR,8aS)-9-(dichloromethylidene)octahydro-1,4-methanonaphthalene-5,8-dione 700-729-0 - - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylic acid 944-682-6 - - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (1R,8S)-2,2,7,7-tetramethyltricyclo[6.2.1.0^{1,6}]undec-5-en-4-one 942-035-2 - - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (1RS, 2SR) (+/-) Methyl trans 2,6,6,-trimethyl-3-cyclohexene-1-carboxylate 453-570-1 - 2016 View substance registered dossier
[Confidential] - - - (1RS, 2SR) (+/-) Methyl trans 2,6,6,-trimethyl-3-cyclohexene-1-carboxylate 453-570-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (1RS, 2SR) (+/-) Methyl trans 2,6,6,-trimethyl-3-cyclohexene-1-carboxylate 453-570-1 - - View substance registered dossier
FIRMENICH GRASSE SAS OR 2 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (1RS,2RS,3RS,6RS,8SR)-8-methoxytricyclo[5.2.1.0(2,6)]decane-3-carbaldehyde; (1RS,2RS,4SR,6RS,8SR)-8-methoxytricyclo[5.2.1.0(2,6)]decane-4-carbaldehyde; reaction mass of: (1RS,2RS,3SR,6RS,9SR)-9-methoxytricyclo[5.2.1.0(2,6)]decane-3-carbaldehyde 429-860-9 - 2013 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (1RS,2RS,3RS,6RS,8SR)-8-methoxytricyclo[5.2.1.0(2,6)]decane-3-carbaldehyde; (1RS,2RS,4SR,6RS,8SR)-8-methoxytricyclo[5.2.1.0(2,6)]decane-4-carbaldehyde; reaction mass of: (1RS,2RS,3SR,6RS,9SR)-9-methoxytricyclo[5.2.1.0(2,6)]decane-3-carbaldehyde 429-860-9 - - View substance registered dossier
Astellas Ireland Co.Ltd Damastown Road Damastown Industrial Park NA Mulhuddart Dublin 15 Ireland Ireland Active (1S)-1,2,3,4-tetrahydro-1-phenylisoquinoline 445-640-5 - 2011 View substance registered dossier
[Confidential] - - - (1S)-1-(3-methoxyphenyl)-N-methylethanamine hydrobromide (1:1) 940-296-7 - - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (1S)-1-cyclopropylethanamine; (2R)-2-hydroxy-2-phenyl-acetic acid 946-290-0 - - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active (1S)-1-cyclopropylethanamine; (2R)-2-hydroxy-2-phenyl-acetic acid 946-290-0 - - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (1S)-1-NAPHTHYLETHYLAMINE 436-100-1 - 2017 View substance registered dossier
Aesica Pharmaceuticals Limited Windmill Industrial Estate Shotton Lane NE23 3JL Cramlington Northumberland United Kingdom United Kingdom No longer Valid (1S)-1-Phenylethanaminium (2S)-2-(2-fluorobiphenyl-4-yl)propanoate 942-079-2 - 2021 View substance registered dossier
- - - - (1S,1'R)-[1-(3',3'-dimethyl-1'-cyclohexyl)ethoxycarbonyl]methyl propanoate 431-700-8 - - View substance registered dossier
[Confidential] - - - (1S,1'R)-[1-(3',3'-dimethyl-1'-cyclohexyl)ethoxycarbonyl]methyl propanoate 431-700-8 - - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (1S,1'R)-[1-(3',3'-dimethyl-1'-cyclohexyl)ethoxycarbonyl]methyl propanoate 431-700-8 - 2011; 2012; 2020 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture (1S,2R)-1-((2R,3R,4S,6S)-3-acetamido-4-(diallylamino)-6-hydroxy-6-(methoxycarbonyl)tetrahydro-2H-pyran-2-yl)propane-1,2,3-triyl triacetate 700-779-3 - 2020 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy - - (1S,2S,5S)-2-(2-chloroethyl)-6,6-dimethylbicyclo[3.1.1]heptane 700-524-6 - - View substance registered dossier
Derivados Químicos S.A. Camino Viejo del Pliego s/n 30820 Alcantarilla Murcia Spain - - (1S,2S,5S)-2-(2-chloroethyl)-6,6-dimethylbicyclo[3.1.1]heptane 700-524-6 - - View substance registered dossier

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