Registered substances
Registered substances
In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).
ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.
As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).
In the portal results table are presented:
- Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
- Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
- Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
- Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
- Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
- Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
- Link to the full factsheet.
A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.
- The REACH Registered substance portal was updated on 9th November 2020; the REACH registered factsheets were further updated on 21st December 2020. Details of the improvements can be found at Dissemination Platform Updates. Reprocessing the entire dataset is ongoing since 21 December 2020. ECHA is making all possible efforts to make the improvements and additional data visible with the shortest delay.
- The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
Further information
- Registered substances information
- How to determine what will be published (Data Submission Manual 15)
- Understanding REACH Regulation
- Q&A on registered substances
- What is an Infocard? [PDF]
- What is a Registered substance Factsheet? [PDF]
- eChemPortal
- REACH study results download
- REACH Regulation
- ECHA Legal notice
Last updated 07 March 2021. Database contains 23184 unique substances and contains information from 93714 dossiers.
Registrant/Supplier | Address | Country | Registration Status | Name | EC / List no. | CAS no. | Last update year | Details |
---|---|---|---|---|---|---|---|---|
ELKEM SILICONES FRANCE S.A.S. | Immeuble DANICA 21, Avenue Georges Pompidou 69003 Lyon France | France | Active | ((2-ethyl-1-oxohexyl)oxy)-(1-phenyl-1,3-decanedionyl)dioctyl stannane; bis(1-phenyl-1,3-decanedionyl)dioctyl stannane; bis[((2-ethyl-1-oxohexyl)oxy)dioctylstannyl]oxide; reaction mass of: bis[(2-ethyl-1-oxohexyl)oxy]dioctyl stannane | 422-920-5 | - | - | View substance registered dossier |
Swords Laboratories | Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland | Ireland | Active | ((4-phenylbutyl)hydroxyphosphoryl)acetic acid | 412-170-7 | 83623-61-4 | - | View substance registered dossier |
SK BIOTEK IRELAND LIMITED | Watery Lane Swords K67 AY91 Swords Co. Dublin Ireland | Ireland | Active | ((6-chloro-4-((2-methoxy-3-(1-methyl-1H-1.2.4-triazol-3-yl)phenyl)amino)pyridazine-3-carbonyl)oxy) hemi-zinc salt | 950-319-2 | - | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | (+)-13-ethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione | 418-490-3 | - | - | View substance registered dossier |
QUIMICA SINTETICA, S.A. | C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain | Spain | Active | (+)-2-aminopropan-1-ol | 220-388-7 | 2749-11-3 | - | View substance registered dossier |
- | - | - | - | (+)-Di-p-anisoyl-D-tartaric Acid | 471-150-6 | 191605-10-4 | - | View substance registered dossier |
Covance Clinical Development SA 169 | Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain | Spain | Active | (+)-Methyloxirane | 604-958-6 | 15448-47-2 | - | View substance registered dossier |
SIPCAM OXON SPA | Via Sempione, 195 20016 Pero Milano Italy | Italy | Active | (+/-) 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazole-1-yl)propyl-1,1,2,2-tetrafluoroethylether | 407-760-6 | 112281-77-3 | - | View substance registered dossier |
- | - | - | - | (+/-) trans-3,3-dimethyl-5-(2,2,3-trimethyl-cyclopent-3-en-1-yl)pent-4-en-2-ol | 411-580-3 | 107898-54-4 | - | View substance registered dossier |
EXPANSIA | Route d'Avignon BP 6 30390 ARAMON France | France | Active | (+/-)-1-[4-Chloro-2-(1-hydroxy-1-phenylethyl)phenyl]-3-ethylthiourea | 924-673-3 | - | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (+/-)-2,3-dihydro-2-hydroxy-3,3-dimethylbenzofuran-5-ylethanesulfonate | 402-720-4 | - | - | View substance registered dossier |
ZaCh System | ZI La Croix Cadeaux 49242 Avrillè France | France | Active | (+/-)-[(R*,R*)and(R*,S*)]-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran | 419-600-2 | 99199-90-3 | - | View substance registered dossier |
Janssen Pharmaceutica N.V. | Turnhoutseweg 30 2340 Beerse Belgium | Belgium | Cease Manufacture | (+/-)-[(R*,R*)and(R*,S*)]-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran | 419-600-2 | 99199-90-3 | 2017 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. | - | - | Active | (+/-)-cis-3-acetoxy-4-phenylazetidine-2-one | 425-840-9 | - | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. | - | - | Active | (+/-)-trans-4-(4-fluorophenyl)-3-hydroxymethyl-N-methylpiperidine | 415-550-0 | 109887-53-8 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (-)(3S,4R)-4-(4-fluorophenyl)-3-(3,4-methylenedioxy-phenoxymethyl)-N-benzylpiperidine hydrochloride | 432-360-3 | 105813-13-6 | - | View substance registered dossier |
Krka, d. d., Novo mesto | Smarjeska cesta 6 SI-8501 Novo mesto Slovenia | Slovenia | Active | (-)-(R)-1-((4-Chlorophenyl)(phenyl)methyl)piperazine | 608-439-5 | 300543-56-0 | - | View substance registered dossier |
CHEMI S.p.A. | Via dei lavoratori, 54 20092 Cinisello balsamo Lombardia Italy | Italy | Active | (-)-trans-4-(4'-fluorophenyl)-3-hydroxymethyl-N-methylpiperidine | 406-030-4 | 105812-81-5 | 2010 | View substance registered dossier |
Thermofisher Scientific Cork Ltd. | Currabinny P43 AY66 Carrigaline Co. Cork Ireland | - | - | (-)-trans-4-(4'-fluorophenyl)-3-hydroxymethyl-N-methylpiperidine | 406-030-4 | 105812-81-5 | - | View substance registered dossier |
- | - | - | - | (-)-trans-4-(4'-fluorophenyl)-3-hydroxymethyl-N-methylpiperidine | 406-030-4 | 105812-81-5 | - | View substance registered dossier |
L.C.M. TRADING SPA | via Mazzini 33 20099 Sesto San Giovanni Lombardia Italy | Italy | Active | (-)-trans-4-(4'-fluorophenyl)-3-hydroxymethyl-N-methylpiperidine | 406-030-4 | 105812-81-5 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | (1,1'-bis(diphenylphosphino)ferrocene)dichloropalladium | 460-040-3 | - | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | (1,5 CYCLOOCTADIEN)RUTHENIUM(II) CHLORID POLYMER | 442-400-1 | - | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | (1,5-cyclooctadiene)(2,4-pentanedionato)rhodium(I) | 456-980-9 | - | - | View substance registered dossier |
Fareva La Vallée | 928 avenue Lavoisier ZI de Blavozy 43700 Saint Germain Laprade Auvergne France | France | Active | (1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol | 601-329-8 | 114798-26-4 | - | View substance registered dossier |
DuPont Solutions (France) SAS | Equinoxe 2 1bis avenue du 8 Mai 1945 78280 Guyancour France | France | Active | (1-[2-[5-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]ACETYL]-4-HETEROMONOCYCLECARBOTHIOAMIDE) | - | - | - | View substance registered dossier |
Giovanni Bozzetto SpA | Via Provinciale, 12 24040 Filago Lombardia Italy | Italy | Active | (1-hydroxydodecylidene)diphosphonic acid | 425-230-2 | 16610-63-2 | - | View substance registered dossier |
REACH24H CONSULTING GROUP | Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland | Ireland | Active | (1-methylethylidene)di-4,1-phenylene tetraphenyl diphosphate | 425-220-8 | 5945-33-5 | 2013; 2015; 2016 | View substance registered dossier |
Shekoy Chemicals Europe B.V. | Kromme Spieringweg 431 2141 AH Vijfhuizen Netherlands | Netherlands | Active | (1-methylethylidene)di-4,1-phenylene tetraphenyl diphosphate | 425-220-8 | 5945-33-5 | - | View substance registered dossier |
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED | Regus Harcourt Centre D02 HW77 Dublin Ireland | Ireland | Cease Manufacture | (1-methylethylidene)di-4,1-phenylene tetraphenyl diphosphate | 425-220-8 | 5945-33-5 | 2014 | View substance registered dossier |
[Confidential] | - | - | - | (10S)-10-hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide | 810-248-9 | 104746-04-5 | - | View substance registered dossier |
Bayer AG | Kaiser-Wilhelm-Allee 51373 Leverkusen Germany | Germany | Active | (13S-cis)-13-ethyl-7,11,12,13,16,17-hexahydro-3-methoxy-6H-cyclopenta[a]phenantren-17-ol | 238-512-3 | 14507-45-0 | - | View substance registered dossier |
Aspen Oss BV | Kloosterstraat 6 5349 AB Oss Netherlands | Netherlands | Active | (17β)-3-oxoestra-4,6-dien-17-yl acetate | 425-330-6 | - | 2011 | View substance registered dossier |
[Confidential] | - | - | - | (1E)-1-(methoxyimino)-1-(2,5,5-trimethyl-1,3-dioxan-2-yl)acetone | 607-917-0 | 263355-39-1 | - | View substance registered dossier |
Saltigo GmbH | HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany | - | - | (1E)-5-methyl-1-phenylhex-1-en-3-one | 808-311-0 | 60796-12-5 | - | View substance registered dossier |
Minakem Dunkerque Production | 224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France | France | Cease Manufacture | (1E)-N-hydroxy-1-(naphthalen-1-yl)ethanimine | 700-765-7 | 100485-51-6 | 2019 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | (1E,Z)-2,6-dimethylhepta-1,5-dienyl 2-methylpropanoate | 479-370-4 | 942594-24-3 | - | View substance registered dossier |
RECORDATI SPA | Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy | Italy | Active | (1R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolinium (2S)-2-(6-methoxy-2-naphthyl)propanoate | 941-846-9 | - | - | View substance registered dossier |
cordenpharma chenove | 47, rue de Longvic 21300 Chenôve France | France | Active | (1R)-2-(benzylamino)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol | 600-381-9 | 1030385-16-0 | - | View substance registered dossier |
cordenpharma chenove | 47, rue de Longvic 21300 Chenôve France | France | Active | (1R)-2-(benzyl{(2R)-2-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl}amino)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol hydrochloride (1:1) | 927-046-2 | 1180001-17-5 | - | View substance registered dossier |
Siegfried PharmaChemikalien Minden GmbH | Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany | Germany | Active | (1R*,6S*)-6-(ethoxycarbonyl)-N,N-dimethyl-6-phenylcyclohex-2-en-1-aminium monooxalate | 700-689-4 | 41524-32-7 | - | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Active | (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxamide | 600-115-1 | 1006376-62-0 | - | View substance registered dossier |
Bayer AG | Kaiser-Wilhelm-Allee 51373 Leverkusen Germany | Germany | Active | (1R,2S)-2,6-dimethyl-2,3-dihydro-1H-inden-1-amine | 700-140-9 | - | 2011 | View substance registered dossier |
Aspen Oss BV | Kloosterstraat 6 5349 AB Oss Netherlands | Netherlands | Active | (1R,2S,10R,11S,15S)-2,15-dimethyl-4-(morpholin-4-yl)-13-(pyrrolidin-1-yl)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-5,14-diol | 601-595-5 | 119302-20-4 | - | View substance registered dossier |
UNION QUIMICO FARMACÉUTICA S.A. | Mallorca 262 08008 Barcelona Barcelona Spain | Spain | Active | (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,5R)-5-hydroxy-1,3-oxathiolane-2-carboxylate | 604-569-1 | 147126-62-3 | - | View substance registered dossier |
Only representative (No publishable name) | - | - | Active | (1R,2S,5R)-5-methyl-2-(propan-2-yl)-N-[2-(pyridin-2-yl)ethyl]cyclohexanecarboxamide | 700-097-6 | 847565-09-7 | 2009; 2011 | View substance registered dossier |
UNION QUIMICO FARMACÉUTICA S.A. | Mallorca 262 08008 Barcelona Barcelona Spain | Spain | Active | (1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate | 939-499-3 | - | - | View substance registered dossier |
Syngenta Ltd | Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom | United Kingdom | No longer Valid | (1R,3S)-3-((1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropanecarbonyl chloride | 614-284-4 | 68127-98-0 | 2021 | View substance registered dossier |
PCAS | 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France | France | Active | (1R,3S,4S)-2-(tert-butoxycarbonyl)-2-azabicyclo[2.2.1]heptane-3-carboxylic acid | 625-288-0 | 291775-59-2 | - | View substance registered dossier |
Symrise AG | Mühlenfeldstraße 1 37603 Holzminden Germany | Germany | Active | (1R,4R)-4-methoxy-2,2,7,7-tetramethyltricyclo(6.2.1.0(1,6))undec-5-ene | 444-480-3 | - | 2011 | View substance registered dossier |
Cheminova A/S | Thyborønvej 76-78 DK-7673 Harboøre Denmark | Denmark | Cease Manufacture | (1R,4R,5S)-6,6-dimethyl-4-(tribromomethyl)-3-oxabicyclo[3.1.0]hexan-2-one | 619-738-5 | 87305-03-1 | 2014 | View substance registered dossier |
Minakem Dunkerque Production | 224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France | France | Active | (1R,5S)-6,6-Dimethyl-3-oxabicyclo[3.1.0]hexane-2,4-dione | 614-164-1 | 67911-21-1 | 2012 | View substance registered dossier |
Symrise AG | Mühlenfeldstraße 1 37603 Holzminden Germany | Germany | Active | (1R,8S)-2,2,7,7-tetramethyltricyclo[6.2.1.0^{1,6}]undec-5-en-4-one | 942-035-2 | - | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (1RS, 2SR) (+/-) Methyl trans 2,6,6,-trimethyl-3-cyclohexene-1-carboxylate | 453-570-1 | - | - | View substance registered dossier |
Astellas Ireland Co.Ltd | Damastown Road Damastown Industrial Park NA Mulhuddart Dublin 15 Ireland | Ireland | Active | (1S)-1,2,3,4-tetrahydro-1-phenylisoquinoline | 445-640-5 | - | 2011 | View substance registered dossier |
H. Lundbeck A/S | Ottiliavej 7-9 2500 Copenhagen Denmark | - | - | (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile | 812-870-6 | 128196-01-0 | - | View substance registered dossier |
MSD International GmbH | Ballydine - Kilsheelan 0 Clonmel Ireland | Ireland | Active | (1S)-1-[3-[(1E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propanol | 608-251-3 | 287930-77-2 | - | View substance registered dossier |
Aesica Pharmaceuticals Limited | Windmill Industrial Estate Shotton Lane NE23 3JL Cramlington Northumberland United Kingdom | United Kingdom | No longer Valid | (1S)-1-Phenylethanaminium (2S)-2-(2-fluorobiphenyl-4-yl)propanoate | 942-079-2 | - | 2021 | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Cease Manufacture | (1S)-2,3,4,6-tetra-O-acetyl-1,5-anhydro-1-(3-{[5-(4-fluorophenyl)-2-thienyl]methyl}-4-methylphenyl)-D-glucitol | 617-901-5 | 866607-35-4 | 2019 | View substance registered dossier |
cordenpharma chenove | 47, rue de Longvic 21300 Chenôve France | France | Active | (1S)-2-(benzylamino)-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol | 603-316-2 | 129050-27-7 | - | View substance registered dossier |
cordenpharma chenove | 47, rue de Longvic 21300 Chenôve France | France | Active | (1S)-2-(benzyl{(2S)-2-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl}amino)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol hydrochloride (1:1) | 807-022-7 | 1224567-85-4 | - | View substance registered dossier |
Esteve Quimica, S.A. | Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain | - | - | (1S)-3-(dimethylamino)-1-(2-thienyl)propan-1-ol | 603-565-7 | 132335-44-5 | - | View substance registered dossier |
SYNTESIA CHEMIE GmbH | Martinistr. 13 20251 Hamburg Germany | Germany | Active | (1S)-3-(dimethylamino)-1-(2-thienyl)propan-1-ol | 603-565-7 | 132335-44-5 | - | View substance registered dossier |
- | - | - | - | (1S,1'R)-[1-(3',3'-dimethyl-1'-cyclohexyl)ethoxycarbonyl]methyl propanoate | 431-700-8 | - | - | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Cease Manufacture | (1S,2R)-1-((2R,3R,4S,6S)-3-acetamido-4-(diallylamino)-6-hydroxy-6-(methoxycarbonyl)tetrahydro-2H-pyran-2-yl)propane-1,2,3-triyl triacetate | 700-779-3 | - | 2020 | View substance registered dossier |
[Confidential] | - | - | - | (1S,3'R,4'S,5'R,6'R)-6-(4-ethylbenzyl)-6'-{[(methoxycarbonyl)oxy]methyl}-3',4',5',6'-tetrahydro-3H-spiro[2-benzofuran-1,2'-pyran]-3',4',5'-triyl trimethyl triscarbonate | 620-506-0 | 1201913-68-9 | - | View substance registered dossier |
[Confidential] | - | - | - | (1S,3'R,4'S,5'S,6'R)-6-(4-ethylbenzyl)-6'-(hydroxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[2-benzofuran-1,2'-pyran]-3',4',5'-triol | 619-989-0 | 903565-83-3 | - | View substance registered dossier |
[Confidential] | - | - | - | (1S,3'R,4'S,5'S,6'R)-6-[(4-ethylphenyl)(hydroxy)methyl]-6'-(hydroxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[2-benzofuran-1,2'-pyran]-3',4',5'-triol | 930-239-4 | 1201913-66-7 | - | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Cease Manufacture | (1S,3R,4R,5R)-methyl 3-acetoxy-4,5-dihydroxycyclohexanecarboxylate | 839-204-7 | 1104200-21-6 | 2020 | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Cease Manufacture | (1S,3R,4R,5S)-methyl 3-acetoxy-5-azido-4-(((2S,3S,4R,5R,6S)-3,4,5-tris(benzyloxy)-6-methyltetrahydro-2H-pyran-2-yl)oxy)cyclohexanecarboxylate | 813-345-4 | 1104200-23-8 | 2020 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. | - | - | Active | (1S,3S,5R,6R)-(4-nitrophenylmethyl)-1-dioxo-6-phenylacetamido-penam-3-carboxylate | 412-670-5 | 54275-93-3 | - | View substance registered dossier |
SK BIOTEK IRELAND LIMITED | Watery Lane Swords K67 AY91 Swords Co. Dublin Ireland | Ireland | Active | (1S,3S,5S)-2-azabicyclo[3.1.0]hexane-3-carboxamide | 615-206-1 | 709031-45-8 | - | View substance registered dossier |
Covance Clinical Development SA 163 | Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 -5 Planta 28050 Madrid Spain | - | - | (1S,4R,4aS,9aR)-4,4a,9,9a-tetrahydro-1H-1,4-methanofluorene | 700-736-9 | - | - | View substance registered dossier |
[Confidential] | - | - | - | (1S,4R,6R)-1-[(3E)-5-hydroxy-3-methylpent-3-en-1-yn-1-yl]-2,2,6-trimethylcyclohexane-1,4-diol | 700-054-1 | 70905-68-9 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. | - | - | Active | (1S,4R,6R,7R)-(4-nitrophenylmethyl)3-methylene-1-oxo-7-phenylacetamido-cepham-4-carboxylate | 412-800-0 | 76109-32-5 | - | View substance registered dossier |
TEVA Pharmaceutical Works Private Ltd. Co. | Pallagi str. 13 H-4042 Debrecen Hungary | Hungary | Active | (1S,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl(2S)-2-methylbutanoate | 700-442-0 | 73573-88-3 | 2012 | View substance registered dossier |
AGC Chemicals Europe, Ltd | World Trade Centre Zuidplein 80 1077VX Amsterdam Netherlands | - | - | (1Z)-1-chloro-2,3,3-trifluoroprop-1-ene | 824-458-3 | 1263679-68-0 | - | View substance registered dossier |
- | - | - | - | (1α5α6α)-6-nitro-3-benzyl-3-azabicyclo[3,1,0]hexane methanesulfonate salt | 426-740-8 | - | - | View substance registered dossier |
Productos Esteve Internacional, S.A | Avd. Verge Montserrat, 12. 08024 Barcelona Barcelona Spain | Spain | Cease Manufacture | (2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol hydrochloride | 700-391-4 | 6953-28-2 | 2017 | View substance registered dossier |
ERM_GmbH_OR14_GUK | Siemenstrasse 9. 63263 Neu Isenburg Hessen Germany | Germany | Active | (2,2-dimethyl-1,3-dioxolan-4-yl)methyl methacrylate | 230-408-6 | 7098-80-8 | - | View substance registered dossier |
Syngenta Ltd | Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom | United Kingdom | No longer Valid | (2,3,5,6-tetrafluoro-4-methylphenyl)methanol | 453-520-9 | - | 2021 | View substance registered dossier |
Shin-Etsu Silicones Europe BV - Importer | Bolderweg 32 1332 AV Almere Netherlands | Netherlands | Active | (2,3-dimethylbut-2-yl)-trimethoxysilane | 439-360-2 | 142877-45-0 | 2013 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | (2,4,6-trioxo-2H,4H,6H-1,3,5-triazine-1,3,5-triyl)triethylene tri(acetoacetate) | 403-570-2 | - | - | View substance registered dossier |
- | - | - | - | (2,4-diaminopteridin-6-yl)methanol hydrobromide | 430-620-0 | 76145-91-0 | - | View substance registered dossier |
Bayer AG | Kaiser-Wilhelm-Allee 51373 Leverkusen Germany | Germany | Active | (2,4-dichlorophenyl)acetyl chloride | 610-950-3 | 53056-20-5 | - | View substance registered dossier |
Stewardship Chemicals 40 | Długosza 67 43-188 Orzesze Poland | Poland | Active | (2,4-Difluorophenyl)(4-Fluorophenyl)methanone | 813-638-7 | 80512-44-3 | - | View substance registered dossier |
F.I.S. Fabbrica Italiana Sintetici S.p.a. | Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy | Italy | Active | (2,5-dibromophenyl)acetic acid | 804-900-1 | 203314-28-7 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol | 437-760-1 | - | - | View substance registered dossier |
ALBEMARLE CHEMICALS S.A.S. | Etang de la Gafette 13521 PORT-DE-BOUC CEDEX France | - | - | (2-(1,3-dioxolan-2-yl)ethyl)triphenylphosphonium bromide | 404-940-6 | 86608-70-0 | - | View substance registered dossier |
[Confidential] | - | - | - | (2-(methylamino)pyridin-3-yl)methyl N-(tert-butoxycabonyl)-N-methylglycinate | 928-404-0 | 1180002-01-0 | - | View substance registered dossier |
Fine Organics Limited | Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom | United Kingdom | No longer Valid | (2-allyloxy-1,1-dimethyl-2-oxo-ethyl) 2-chloro-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1(2H)-pyrimidin-1-yl]benzoate | 603-837-5 | 134605-64-4 | 2021 | View substance registered dossier |
EXPANSIA | Route d'Avignon BP 6 30390 ARAMON France | France | Active | (2-benzyl-acryloylamino)-acetic acid benzyl ester | 921-619-0 | - | - | View substance registered dossier |
[Confidential] | - | - | - | (2-bromo-5-fluorophenyl)methanol | 606-492-9 | 202865-66-5 | - | View substance registered dossier |
Kao Chemicals GmbH | Kupferstrasse 1 46446 Emmerich Northrhine-Westfalia Germany | Germany | Active | (2-butoxyethoxy)acetic acid | 451-650-0 | - | 2010 | View substance registered dossier |
Sterling Pharma Solutions Ltd | Dudley NE23 7QG Cramlington Northumberland United Kingdom | United Kingdom | No longer Valid | (2-Butyl-5-nitro-1-benzofuran-3-yl)(4-hydroxyphenyl)methanone | 464-300-7 | - | 2021 | View substance registered dossier |
sanofi chimie | 82 avenue Raspail 94250 Gentilly France | France | Active | (2-butyl-5-nitrobenzofuran-3-yl)[4-(3-dibutylaminopropoxy)phenyl]methanone | 444-800-1 | 141645-23-0 | 2010 | View substance registered dossier |
QUIMICA SINTETICA, S.A. | C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain | Spain | Active | (2-carbamimidamido-1,3-thiazol-4-yl)methyl carbamimidothioate dihydrochloride | 618-106-6 | 88046-01-9 | 2011 | View substance registered dossier |
PCAS | 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France | France | Active | (2-chloro-5-iodophenyl)(4-methoxyphenyl)methanone | 810-422-4 | 1459754-39-2 | - | View substance registered dossier |
[Confidential] | - | - | - | (2-ethoxy-1-methyl-2-oxoethyl)-5-[[]2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoate | 616-466-9 | 77501-63-4 | - | View substance registered dossier |
[Confidential] | - | - | - | (2-ethoxy-1-methyl-2-oxoethyl)triphenylphosphonium bromide | 250-002-2 | 30018-16-7 | - | View substance registered dossier |
Amri Italy S.r.l. | VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy | Italy | Active | (2-formamido-1,3-thiazol-4-yl)(oxo)acetic acid | 613-733-1 | 64987-06-0 | - | View substance registered dossier |
Corden Pharma Latina S.p.A. | Via del Murillo Km 2, 800 IT04013 Sermoneta (LT) Lazio Italy | - | - | (2-formamido-1,3-thiazol-4-yl)(oxo)acetic acid | 426-680-2 | - | - | View substance registered dossier |
Euticals SAS | ZI de Laville 47240 BON-ENCONTRE France | France | Active | (2-formamido-1,3-thiazol-4-yl)(oxo)acetic acid | 426-680-2 | - | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (2-hydroxy-3-(3,4-dimethyl-9-oxo-10-thiaanthracen-2-yloxy)propyl)trimethylammonium chloride | 402-200-7 | 103430-24-6 | - | View substance registered dossier |
BASF SE | Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany | Germany | Cease Manufacture | (2-hydroxyethyl)(3-hydroxypropyl)dimethylammonium chloride | 278-860-3 | 78182-00-0 | 2020 | View substance registered dossier |
Albemarle Germany GmbH | Industriepark Höchst Gebäude G 879 65926 Frankfurt Germany | Germany | Active | (2-methylpropyl)lithium; isobutyllithium | 440-620-2 | 920-36-5 | 2010 | View substance registered dossier |
Novo Nordisk A/S | Novo Alle 2880 Bagsværd Denmark | Denmark | Active | (22S)-22-carboxy-1-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,10,19,24-tetraoxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontan-41-oic acid | 815-717-1 | 1169630-40-3 | - | View substance registered dossier |
Pliva Hrvatska doo | Prilaz baruna Filipovića 25 10000 Zagreb Croatia | Croatia | Active | (2E)-2-[(1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)methylene]-5,6-dimethoxyindan-1-one hydrochloride (1:1) | 940-983-1 | - | - | View substance registered dossier |
IFF Benicarlo, S.L. | Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain | Spain | Active | (2E)-3,7-dimethylocta-2,6-dien-1-amine | 700-035-8 | 6246-48-6 | - | View substance registered dossier |
Symrise AG | Mühlenfeldstraße 1 37603 Holzminden Germany | Germany | Active | (2E,4E)-2-methyl-5-phenyl-penta-2,4-dienal | 919-772-3 | - | - | View substance registered dossier |
- | - | - | - | (2E,4E)-Isobutyl-deca-2,4-dienamide | 457-600-4 | 18836-52-7 | - | View substance registered dossier |
Novartis Integrated Services Limited | Ringaskiddy IE Ringaskiddy Cork Ireland | Ireland | Active | (2E,4R)-5-{[1,1’-biphenyl]-4-yl}-4-[(tert-butoxycarbonyl)amino]-2-methylpent-2-enoic acid | 695-654-2 | 1012341-48-8 | 2014 | View substance registered dossier |
PIERRE FABRE MEDICAMENT | 45 place Abel Gance 92654 Boulogne France | France | Active | (2R)-2,8-dimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-yl beta-D-glucopyranoside | 805-675-2 | 102340-61-4 | - | View substance registered dossier |
MINAKEM Beuvry Production SAS | 145, Chemin des Lilas 59310 Beuvry-la-Forêt France | France | Active | (2R)-2-(2,5-difluorophenyl)pyrrolidine, (2R,3R)-2,3-bis[(4-methoxybenzoyl)oxy]butanedioic acid | 951-764-5 | - | - | View substance registered dossier |
Deretil S.A. | Villaricos, s/n 04618 Cuevas del Almanzora Almeria Spain | - | - | (2R)-2-amino-2-phenylacetamide | 420-370-0 | 6485-67-2 | - | View substance registered dossier |
- | - | - | - | (2R)-2-amino-2-phenylacetamide | 420-370-0 | 6485-67-2 | - | View substance registered dossier |
BASF SE | Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany | Germany | Active | (2R)-4-hydroxybutan-2-aminium (2S)-hydroxy(phenyl)acetate | 810-156-9 | 1236049-43-6 | 2016 | View substance registered dossier |
cordenpharma chenove | 47, rue de Longvic 21300 Chenôve France | France | Active | (2R)-6-fluorochromane-2-carboxylic acid | 810-841-2 | 129101-37-7 | - | View substance registered dossier |
Excella GmbH & Co. KG | Nuernberger Str. 12 90537 Feucht Germany | Germany | Active | (2R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide - (2R,3R)-2,3-dihydroxysuccinic acid - propan-2-ol (2:1:1) | 947-841-8 | - | - | View substance registered dossier |
Pfizer Ltd | Ramsgate Road (IPC 979) CT13 9NJ Sandwich Kent United Kingdom | United Kingdom | No longer Valid | (2R*,3S*)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol (1R)-10-camphorsulfonate | 427-100-0 | - | 2021 | View substance registered dossier |
MINAKEM Beuvry Production SAS | 145, Chemin des Lilas 59310 Beuvry-la-Forêt France | France | Active | (2R,3R)-2,3-bis[(4-methoxybenzoyl)oxy]butanedioic acid | 672-585-6 | 50583-51-2 | - | View substance registered dossier |
Excella GmbH & Co. KG | Nuernberger Str. 12 90537 Feucht Germany | Germany | Active | (2R,3R)-2,3-Dihydroxybutanedioic acid--(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide (1/1) | 947-840-2 | - | - | View substance registered dossier |
L.C.M. TRADING SPA | via Mazzini 33 20099 Sesto San Giovanni Lombardia Italy | Italy | Active | (2R,3R)-3-((R)-1-(tert-butyldimethylsiloxy)ethyl)-4-oxoazetidin-2-yl acetate | 408-050-9 | 76855-69-1 | - | View substance registered dossier |
[Confidential] | - | - | - | (2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide | 609-299-8 | 368421-58-3 | - | View substance registered dossier |
[Confidential] | - | - | - | (2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-(benzoyloxymethyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate | 807-677-9 | 817204-32-3 | - | View substance registered dossier |
Bayer AG | Kaiser-Wilhelm-Allee 51373 Leverkusen Germany | Germany | Active | (2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol | 606-239-2 | 19130-96-2 | 2011; 2012 | View substance registered dossier |
Janssen Pharmaceutica N.V. | Turnhoutseweg 30 2340 Beerse Belgium | Belgium | Active | (2R,3R,4S,5R)-2-(acetoxymethyl)-6-oxotetrahydro-2H-pyran-3,4,5-triyl triacetate | 612-107-5 | 61259-48-1 | - | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Cease Manufacture | (2R,3R,4S,5R)-2-(acetoxymethyl)-6-oxotetrahydro-2H-pyran-3,4,5-triyl triacetate | 612-107-5 | 61259-48-1 | 2019 | View substance registered dossier |
Euticals SAS | ZI de Laville 47240 BON-ENCONTRE France | France | Active | (2R,3S,4R,5R)-2,3,4,6-tetrakis(benzyloxy)-5-hydroxy-1-(4-methylpiperazin-1-yl) hexan-1-one | 829-550-7 | 1431329-04-2 | - | View substance registered dossier |
Pliva Hrvatska doo | Prilaz baruna Filipovića 25 10000 Zagreb Croatia | Croatia | Active | (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one | 616-385-9 | 76801-85-9 | - | View substance registered dossier |
SUANFARMA Italia SpA | Corso Verona, 165 38068 Rovereto Trentino Alto Adige Italy | Italy | Active | (2R-(2α,3Z,5α))-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 1:1 salt with 2,4,4-Trimethylpentan-2-amine | 613-879-6 | 66069-32-7 | - | View substance registered dossier |
Indivior UK Ltd | Henry Boot Way HU4 7DY Hull United Kingdom | United Kingdom | No longer Valid | (2S)-(5α,7α)-7-(2-hydroxy-3,3-dimethylbutan-2-yl)-3,6-dimethoxy-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-17-carbonitrile | 605-429-2 | 16614-60-1 | 2021 | View substance registered dossier |
Indivior UK Ltd | Henry Boot Way HU4 7DY Hull United Kingdom | United Kingdom | No longer Valid | (2S)-(5α,7α)-7-(2-hydroxy-3,3-dimethylbutan-2-yl)-6-methoxy-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-3-ol | 682-862-3 | 78715-23-8 | 2021 | View substance registered dossier |
[Confidential] | - | - | - | (2S)-1-tert-butoxycarbonyl-2,3-dihydropyrrole-2-carboxylic acid;N-cyclohexylcyclohexanamine | 618-453-3 | 90104-21-5 | - | View substance registered dossier |
MinAscent Leuna Production GmbH | Am Haupttor Gebäude 4208 06237 Leuna Germany | Germany | Active | (2S)-2-(benzyloxy)-1-(pyrrolidin-1-yl)propan-1-one | 601-832-2 | 122151-32-0 | - | View substance registered dossier |
MinAscent Leuna Production GmbH | Am Haupttor Gebäude 4208 06237 Leuna Germany | Germany | Active | (2S)-2-(benzyloxy)propanal | 617-235-5 | 81445-44-5 | - | View substance registered dossier |
Indivior UK Ltd | Henry Boot Way HU4 7DY Hull United Kingdom | United Kingdom | No longer Valid | (2S)-2-[(5α,7α)-3,6-dimethoxy-17-methyl-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-7-yl]-3,3-dimethylbutan-2-ol | 605-274-0 | 16196-70-6 | 2021 | View substance registered dossier |
ROLABO OUTSOURCING, S.L. | Polígono Industrial Malpica. Calle J, nº 3-4 50016 Zaragoza Zaragoza Spain | Spain | Active | (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid | 406-310-6 | - | - | View substance registered dossier |
FARMHISPANIA S.A. | Passeig del Riu Besós, 9-10 08160 Montmeló Barcelona Spain | Spain | Active | (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid | 406-310-6 | - | - | View substance registered dossier |
TAMARANG, S.A. | Balmes, 84, 4-2 08008 Barcelona Barcelona Spain | Spain | Cease Manufacture | (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid | 406-310-6 | - | 2012 | View substance registered dossier |
Flamma S.p.a. | via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy | Italy | Active | (2S)-2-amino-3-(4-hydroxyphenyl)propanal semicarbazone hydrochloride (1:1) | 940-825-1 | - | - | View substance registered dossier |
MITSUBISHI GAS CHEMICAL EUROPE GMBH | Immermannstr.13 40210 Duesseldorf Germany | Germany | Cease Manufacture | (2S)-2-Aminobutyramide Hydrochloride | 471-490-5 | 7682-20-4 | 2013 | View substance registered dossier |
Flamma S.p.a. | via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy | Italy | Active | (2S)-2-Benzyl-N,N-dimethylaziridine-1-sulfonamide | 620-285-0 | 902146-43-4 | - | View substance registered dossier |
MinAscent Leuna Production GmbH | Am Haupttor Gebäude 4208 06237 Leuna Germany | Germany | Active | (2S)-2-hydroxy-1-(1-pyrrolidinyl)-1-propanone | 601-833-8 | 122151-38-6 | - | View substance registered dossier |
Bayer AG | Kaiser-Wilhelm-Allee 51373 Leverkusen Germany | Germany | Active | (2S)-4-amino-2-hydroxybutanoic acid | 670-305-7 | 40371-51-5 | - | View substance registered dossier |
Evonik Rexim S.A.S. | 33, Rue de Verdun 80400 Ham France | France | Active | (2S)-5-amino-2-[(aminoacetyl)amino]-5-oxopentanoic acid | 700-144-0 | 13115-71-4 | - | View substance registered dossier |
Evonik Rexim S.A.S. | 33, Rue de Verdun 80400 Ham France | France | Active | (2S)-5-amino-2-{[(2S)-2-aminopropanoyl]amino}-5-oxopentanoic acid | 475-290-9 | - | - | View substance registered dossier |
cordenpharma chenove | 47, rue de Longvic 21300 Chenôve France | France | Active | (2S)-6-fluoro-3,4-dihydro-2H-1-Benzopyran-2-carboxylic acid | 810-842-8 | 129101-36-6 | - | View substance registered dossier |
Janssen Pharmaceutica N.V. | Turnhoutseweg 30 2340 Beerse Belgium | Belgium | Cease Manufacture | (2S)-[[(benzyloxy)carbonyl]amino](cyclohexyl)acetic acid | 478-210-0 | 69901-75-3 | 2019 | View substance registered dossier |
Envigo Consulting Limited | Woolley Road Alconbury PE28 4HS Huntingdon Cambridgeshire United Kingdom | United Kingdom | Cease Manufacture | (2S)-[[(benzyloxy)carbonyl]amino](cyclohexyl)acetic acid | 478-210-0 | 69901-75-3 | 2019 | View substance registered dossier |
Envigo Consulting Limited | Woolley Road Alconbury PE28 4HS Huntingdon Cambridgeshire United Kingdom | United Kingdom | No longer Valid | (2S)-[[(benzyloxy)carbonyl]amino](cyclohexyl)acetic acid | 478-210-0 | 69901-75-3 | 2021 | View substance registered dossier |
MINAKEM Beuvry Production SAS | 145, Chemin des Lilas 59310 Beuvry-la-Forêt France | France | Active | (2S)-but-3-yn-2-yl methanesulfonate | 857-677-8 | 73647-37-7 | - | View substance registered dossier |
Excella GmbH & Co. KG | Nuernberger Str. 12 90537 Feucht Germany | Germany | Active | (2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide | 617-525-1 | 84057-95-4 | - | View substance registered dossier |
Wacker Chemie AG | Hanns-Seidel-Platz 4 81737 Muenchen Germany | Germany | Cease Manufacture | (2S)-pentan-2-ol | 700-266-4 | 26184-62-3 | 2016 | View substance registered dossier |
FINORGA SAS | 497 route de Givors 38670 CHASSE SUR RHONE France | France | Active | (2S)-propane-1,2-diamine dihydrochloride | 606-377-3 | 19777-66-3 | - | View substance registered dossier |
Flamma S.p.a. | via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy | Italy | Active | (2S,3R)-3-methoxy-2-(methoxycarbonylamino)butanoic acid | 800-213-6 | 1007881-21-1 | - | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Active | (2S,3R,4R,5S,6R)-3,4,5-tris(benzyloxy)-2-methyl-6-(p-tolylthio)tetrahydro-2H-pyran | 835-228-7 | 211801-54-6 | - | View substance registered dossier |
bitop AG | Stockumer Str. 28 58453 Witten Germany | Germany | Active | (2S,3R,4S,5S,6R)-2-(1,3-dihydroxypropan-2-yloxy)-6-(hydroxymethyl)oxane-3,4,5-triol | 824-773-6 | 22160-26-5 | 2018 | View substance registered dossier |
Warsaw University of Technology, Faculty of Chemistry, Laboratory of Technological Processes | Noakowskiego 3 00-664 Warszawa Poland | Poland | Cease Manufacture | (2S,3S)-2,3-Bis((4-methoxybenzoyl)oxy)succinic acid | 606-247-6 | 191605-10-4 | 2014 | View substance registered dossier |
Janssen Pharmaceutica N.V. | Turnhoutseweg 30 2340 Beerse Belgium | Belgium | Cease Manufacture | (2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride | 478-270-8 | - | 2019 | View substance registered dossier |
Envigo Consulting Limited | Woolley Road Alconbury PE28 4HS Huntingdon Cambridgeshire United Kingdom | United Kingdom | No longer Valid | (2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride | 478-270-8 | - | 2021 | View substance registered dossier |
Novartis Integrated Services Limited | Ringaskiddy IE Ringaskiddy Cork Ireland | Ireland | Active | (2S,3S,3aR,9aS)-3-hydroxy-2-(hydroxymethyl)-7-methyl-2,3,3a,9a-tertryhydro-6H-furo[2’,3’:4,5][1,3]oxazolo [3,2-a]pyrimidin-6-one | 700-330-1 | 433733-92-7 | 2008; 2010; 2019 | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Active | (2S,3S,4R)-2-aminooctadecane-1,3,4-triol | 439-210-6 | 554-62-1 | 2011 | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Active | (2S,5R)-5-[(benzyloxy)amino]piperidine-2-carboxamide | 812-263-6 | 1416134-49-0 | - | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Active | (2S,5R)-5-[(benzyloxy)ammonio]-2-[(benzyloxy)carbonyl]piperidinium oxalate | 810-636-8 | 1171080-45-7 | - | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Active | (2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide | 812-287-7 | 1192651-49-2 | - | View substance registered dossier |
INTEROR | 49, rue d'Ostende F-62100 CALAIS France | France | Active | (2S-cis)-(diphenylmethyl)-N-(phenylmethyl)-1-azabicyclo[2.2.2.]octan-3-amine (1-R camphor-10-sulfonate) | 444-810-6 | - | 2014 | View substance registered dossier |
Fine and Performance Chemicals Ltd | Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom | United Kingdom | No longer Valid | (2Z)-(5-amino-1,2,4-thiadiazol-3-yl)(ethoxyimino)acetic acid | 616-178-3 | 75028-24-9 | 2021 | View substance registered dossier |
ACS DOBFAR S.p.A | Viale Addetta 4/12 20067 Tribiano Milano Italy | Italy | Active | (2Z)-(5-amino-1,2,4-thiadiazol-3-yl){[(1-tert-butoxy-2-methyl-1-oxopropan-2-yl)oxy]imino}acetic acid | 616-285-5 | 76028-96-1 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (2Z)-2-phenylhex-2-enenitrile | 482-160-5 | 130786-09-3 | - | View substance registered dossier |
FIS Fabbrica Italiana Sintetici SpA | Viale Milano, 26 36075 Montecchio Maggiore (Vicenza) Italy | Italy | Active | (2Z)-3-(3-chloro-2-fluorophenyl)-2-(4-chloro-2-fluorophenyl)acrylonitrile | 806-533-2 | 1219086-87-9 | 2016 | View substance registered dossier |
F.I.S. Fabbrica Italiana Sintetici S.p.a. | Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy | Italy | Active | (2Z)-3-amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)but-2-en-1-one | 616-378-0 | 767340-03-4 | - | View substance registered dossier |
Lanxess Deutschland GmbH | Kennedyplatz 1 50569 Köln Germany | Germany | Active | (2Z,16Z)-4,15-dioxo-5,8,11,14-tetraoxaoctadeca-2,16-diene-1,18-dioic acid | 806-734-5 | 109828-01-5 | - | View substance registered dossier |
Aspen Oss BV | Kloosterstraat 6 5349 AB Oss Netherlands | - | - | (2β,3α,5α,16β,17β)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane | 601-596-0 | 119302-24-8 | - | View substance registered dossier |
Aspen Oss BV | Kloosterstraat 6 5349 AB Oss Netherlands | - | - | (3 β, 5 α, 6β)-3-(acetyloxy)-5-bromo-6-hydroxy-androstan-17-one | 419-790-7 | 4229-69-0 | - | View substance registered dossier |
UNION QUIMICO FARMACÉUTICA S.A. | Mallorca 262 08008 Barcelona Barcelona Spain | Spain | Active | (3,3-diethoxy-1-propenyl)benzene | 230-467-8 | 7148-78-9 | - | View substance registered dossier |
CENTIPHARM | Chemin de la Madeleine 06131 GRASSE FRANCE France | France | Active | (3,4,5-trifluorophenyl)boronic acid | 604-355-8 | 143418-49-9 | 2008; 2010 | View substance registered dossier |
Saltigo GmbH | HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany | Germany | Cease Manufacture | (3,4-Dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl)-methylamine | 917-818-7 | 73344-75-9 | 2013 | View substance registered dossier |
Wacker Chemie AG | Hanns-Seidel-Platz 4 81737 Muenchen Germany | Germany | Active | (3-(4-((((3β)-cholest-5-en-yl)oxy)carbonyl)phenoxy)propylmethyl-co-3-(4-((2-methyl-2-propenoyloxy)phenyloxy)carbonyl)-phenoxy)propylmethyl)cyclotetrasiloxane) | 454-660-3 | - | - | View substance registered dossier |
Clariant Ibérica Producción S.A. | Avda. Baix Llobregat, 3-5 08970 Sant Joan Despí Barcelona Spain | Spain | Active | (3-(C20-24-(even numbered)-alkyl-2-enyl)-dihydro-furan-2,5-dion | 615-230-2 | 70983-53-8 | - | View substance registered dossier |
Boehringer Ingelheim Pharma GmbH & Co. KG | Binger Strasse 173 55216 Ingelheim am Rhein Germany | Germany | Cease Manufacture | (3-aminophenyl)pyridin-3-ylmethanone | 428-230-0 | 79568-06-2 | 2015 | View substance registered dossier |
F.I.S. Fabbrica Italiana Sintetici S.p.a. | Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy | Italy | Active | (3-chloro-2-fluorophenyl)(2,4-dimethoxyphenyl)methanone | 689-199-9 | 680610-70-2 | - | View substance registered dossier |
Ricardo Nederland BV | Catharijnesingel 33 3511 GC Utrecht Netherlands | Netherlands | Active | (3-chloro-2-hydroxypropyl)dimethyloctadecylammonium chloride | 221-083-1 | 3001-63-6 | - | View substance registered dossier |
Clariant Produkte (Deutschland) GmbH | Am Unisys-Park 1 65843 Sulzbach am Taunus Germany | Germany | Active | (3-chloro-2-hydroxypropyl)trimethylammonium chloride | 222-048-3 | 3327-22-8 | - | View substance registered dossier |
Boehringer Ingelheim Pharma GmbH & Co. KG | Binger Strasse 173 55216 Ingelheim am Rhein Germany | Germany | Active | (3-Chloro-4-fluoro-phenyl)-{6-nitro-7-[(S)-(tetrahydro-furan-3-yl)oxy]-quinazolin-4-yl}-amine | 925-395-5 | - | - | View substance registered dossier |
LA MESTA CHIMIE FINE | 1336 Route de l'Estéron 06830 GILETTE France | France | Active | (3-chloro-4-methoxyphenyl)methanaminium chloride | 609-972-6 | 41965-95-1 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. | - | - | Active | (3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone | 423-290-4 | 66938-41-8 | - | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Active | (3-endo)-8-benzyl-8-azabicyclo[3.2.1]octan-3-amine (2E)-but-2-enedioate (1:1) | 943-085-8 | - | - | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Cease Manufacture | (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl methanesulfonate | 700-367-3 | 35130-97-3 | 2012 | View substance registered dossier |
Miltitz Aromatics GmbH | Chemiepark Bitterfeld-Wolfen Riechstoffstrasse 1 06803 Bitterfeld-Wolfen Germany | - | - | (3-Methyl-but-2-enyloxy)-benzol | 846-080-8 | 14309-15-0 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | (3-Phenyl-1H-inden-1-ylidene)bis(tricyclohexylphosphine)ruthenium(IV) Dichloride Tetrahydrofuran Adduct | 480-140-0 | 250220-36-1 | - | View substance registered dossier |
[Confidential] | - | - | - | (3aR,4R,5R,7S,8S,9R,9aS,12R)-8-hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-(((1R,2R,4R)-4-amino-2-hydroxycyclohexyl)thio)acetate | 813-124-2 | 1061337-51-6 | - | View substance registered dossier |
Minakem Dunkerque Production | 224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France | France | Cease Manufacture | (3aR,6S)-8,8-dimethyl-4,5,6,7-tetrahydro-3a,6-methano-2,1-benzothiazole 2,2-dioxide | 621-464-6 | 107869-45-4 | 2019 | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Cease Manufacture | (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl[(methylsulfonyl)oxy]acetate | 700-396-1 | 60924-38-1 | 2012 | View substance registered dossier |
DSM Pharma Chemicals Venlo B.V. | Grubbenvorsterweg 8 Postbox 81 5900 AB Venlo Netherlands | Netherlands | Active | (3AS,4S,6AR)-4-METHOXYTETRAHYDROFURO[3,4- B]FURAN-2(3H)-ONE | 443-930-6 | - | - | View substance registered dossier |
Janssen Pharmaceutica N.V. | Turnhoutseweg 30 2340 Beerse Belgium | Belgium | Cease Manufacture | (3beta)-17-(3-pyridinyl)androsta-5,16-dien-3-yl acetate compound with (2R,3R)-tartaric acid and methanol (1 : 1 : 1.5) | 931-336-4 | - | 2019 | View substance registered dossier |
PharmaZell GmbH | Rosenheimer Straße 43 D-83064 Raubling Germany | Germany | Active | (3E)-3-[[4-(2-carboxyethylcarbamoyl)phenyl]hydrazinylidene]-6-oxocyclohexa-1,4-diene-1-carboxylic acid | 617-116-8 | 80573-04-2 | 2019 | View substance registered dossier |
PFW Aroma Ingredients B.V. | Veemweg 29-31 3771 MT Barneveld Gelderland Netherlands | Netherlands | Active | (3E)-4-[(1S,3aS,4R,7aS)-1,7a-dimethyloctahydro-4H-1,4-methanoinden-4-yl]pent-3-en-2-one | 948-498-7 | 143785-33-5 | 2019 | View substance registered dossier |
Symrise AG | Mühlenfeldstraße 1 37603 Holzminden Germany | Germany | Active | (3E)-non-3-en-2-one | 813-141-5 | 18402-83-0 | - | View substance registered dossier |
F.I.S. Fabbrica Italiana Sintetici S.p.a. | Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy | Italy | Active | (3R)-3-amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one | 690-730-1 | 486460-32-6 | - | View substance registered dossier |
[Confidential] | - | - | - | (3R,4S,5R,6R)-3,4,5-tris[(trimethylsilanyl)oxy]-6-{[(trimethylsilanyl)oxy]methyl}tetrahydro-2H-pyran-2-one | 608-732-8 | 32384-65-9 | - | View substance registered dossier |
Sandoz Industrial Products SA | Ctra. Granollers - Cardedeu C-251, Km 4 08520 Les Franqueses del Vallés Spain | Spain | Active | (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-10-(hydroxyimino)-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one hydrochloride | 607-864-3 | 26116-57-4 | - | View substance registered dossier |
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