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Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The REACH Registered substance portal was updated on 9th November 2020; the REACH registered factsheets were further updated on 21st December 2020. Details of the improvements can be found at Dissemination Platform Updates. Reprocessing the entire dataset is ongoing since 21 December 2020. ECHA is making all possible efforts to make the improvements and additional data visible with the shortest delay.
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
Last updated 20 January 2021. Database contains 23121 unique substances and contains information from 101751 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
Select total tonnage band range:

0

Infinite



Uses and exposure
Life cycle:
  • Consumer Uses
  • Article service life
  • Widespread uses by professional workers
  • Formulation or re-packing
  • Uses at industrial sites
  • Manufacture
Category:
Details
(3Z)-hex-3-en-1-yl 2-methylprop-2-en-1-yl ether
439-790-0 292605-05-1 Active Full Individual ≥ 0 to < 10 tonnes 18-01-2013 View substance registered dossier
(3Z)-hex-3-en-1-yl cyclopropanecarboxylate
425-200-9 - Active Full Joint ≥ 1 to < 10 tonnes 17-12-2012 View substance registered dossier
(3α,5β,7β)-3,7-Dihydroxy-24-norcholane-23-nitrile
828-107-5 118316-12-4 null Intermediate Joint Intermediate Use Only 25-05-2020 View substance registered dossier
(3β)-17-(1,1,1-trifluoromethanesulfonate)-Androsta-5,16-diene-3,17-diol, 3-(2,2,2-trifluoroacetate)
840-627-4 1802323-89-2 Active Intermediate Joint Intermediate use only 26-06-2019 View substance registered dossier
(3β)-3-[(2,2,2-trifluoroacetyl)oxy]-Androst-5-en-17-one
840-626-9 3798-17-2 null Intermediate Joint Intermediate Use Only 25-05-2020 View substance registered dossier
(3β,20β)-3-acetoxy-11-oxoolean-12-en-29-oic acid
228-475-1 6277-14-1 Active Full Joint ≥ 0 to < 10 tonnes 27-06-2019 View substance registered dossier
(3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-yl butyrate
250-567-5 31316-20-8 null Intermediate Joint Intermediate Use Only 13-04-2020 View substance registered dossier
(4'-methyl-3-fluoro[1,1'-biphenyl]-4-yl)-boronic acid
813-651-8 1698890-39-9 Active Full Joint ≥ 1 to < 10 tonnes 14-05-2018 View substance registered dossier
(4,5-dibromo-1H-pyrrol-2-yl)(phenyl)methanone
700-338-5 50372-61-7 null Intermediate Joint Intermediate Use Only 30-03-2020 View substance registered dossier
(4-(1-methylethyl)phenyl)-(4-methylphenyl)iodonium tetrakis(pentafluorophenyl)borate (1-) 422-960-3 178233-72-2 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(4-(3,4-dichloro-phenyl)-3,4-dihydro-2H-naphthalen-1-ylidene)-methyl-amide
455-240-2 - null NONS Individual Tonnage Data Confidential 25-08-2020 View substance registered dossier
(4-(4-(4-dimethylaminobenzyliden-1-yl)-3-methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid
410-430-4 117573-89-4 null NONS Individual Tonnage Data Confidential 30-03-2020 View substance registered dossier
(4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone
613-265-8 63590-64-7 Active Intermediate Joint Intermediate use only 25-07-2018 View substance registered dossier
(4-(4-aminophenyl)(4-iminocyclohexa-2,5-dienylidene)methyl)-2-methylaniline hydrochloride
211-189-6 632-99-5 null Full Joint 0 - 10 tonnes per annum 01-09-2020 View substance registered dossier
(4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-phenylamino)-acetic acid ethyl ester
927-587-4 872728-83-1 null Intermediate Joint Intermediate Use Only 30-04-2020 View substance registered dossier
(4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazole-3-yl)phenylamino)acetic acid
460-450-2 872728-82-0 Active Intermediate Joint Intermediate use only 17-05-2019 View substance registered dossier
(4-(6-diethylamino-2-methylpyridin-3-yl)imino-4,5-dihydro-3-methyl-1-(4-methylphenyl)-1H-pyrazol-5-one
427-070-9 - null NONS Individual Tonnage Data Confidential 02-04-2020 View substance registered dossier
(4-6) PEPTIDE
427-550-8 - null NONS Individual Tonnage Data Confidential 02-04-2020 View substance registered dossier
(4-acetamido-2,2,6,6-tetramethyl-1-piperidinyl)oxidanyl; N-(2,2,6,6-tetramethyl-1-oxylpiperidin-4-yl)acetamide
423-840-3 14691-89-5 null NONS Individual Tonnage Data Confidential 05-08-2020 View substance registered dossier
(4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid;hydrate
680-378-7 138624-11-0 null Full Joint 0 - 10 tonnes per annum 22-05-2020 View substance registered dossier
(4-amino-2-chloro-5-methylphenyl)(4-chlorophenyl)acetonitrile
262-792-6 61437-85-2 Active Intermediate Joint Intermediate use only 09-03-2018 View substance registered dossier
(4-aminophenyl)-N-methylmethylenesulfonamide hydrochloride
406-010-5 88918-84-7 null NONS Individual Tonnage Data Confidential 30-03-2020 View substance registered dossier
(4-benzylpiperazin-1-yl)(cyclopropyl)methanone hydrochloride
816-907-7 1294454-93-5 null Intermediate Joint Intermediate Use Only 05-08-2020 View substance registered dossier
(4-butoxy-2,3-difluorophenyl)boronic acid
692-793-0 156487-12-6 Active Full Joint ≥ 1 to < 10 tonnes 16-05-2018 View substance registered dossier
(4-carboxybutyl)triphenylphosphonium bromide
241-782-5 17814-85-6 Active Intermediate Joint Intermediate use only 15-12-2015 View substance registered dossier
(4-chloro-2-fluoro-3-methoxyphenyl)boronic acid
696-001-4 944129-07-1 null Intermediate Individual Intermediate Use Only 06-07-2020 View substance registered dossier
(4-chloro-2-fluorophenyl)acetonitrile
642-783-7 75279-53-7 Cease Manufacture Intermediate Individual Cease manufacture 30-03-2016 View substance registered dossier
(4-Chloro-3-(4-ethoxybenzyl)phenyl)((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanone
695-300-7 1103738-30-2 null Intermediate Joint Intermediate Use Only 16-10-2020 View substance registered dossier
(4-chlorophenyl)(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol
814-124-5 133545-64-9 null Intermediate Joint Intermediate Use Only 25-05-2020 View substance registered dossier
(4-chlorophenyl)hydrazine
214-029-3 1073-69-4 Active Intermediate Individual Intermediate use only 28-09-2010 View substance registered dossier
(4-chlorophenyl)hydrazine
214-029-3 1073-69-4 No longer Valid Intermediate Individual No longer valid 13-11-2013 View substance registered dossier
(4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid
826-639-2 1817776-86-5 Active Intermediate Joint Intermediate use only 20-07-2020 View substance registered dossier
(4-ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane
405-020-7 105024-66-6 null NONS Individual Tonnage Data Confidential 02-04-2020 View substance registered dossier
(4-fluorobenzenide)magnesium(1+)bromide
627-087-3 352-13-6 Active Intermediate Joint Intermediate use only 06-06-2016 View substance registered dossier
(4-fluorophenyl)-isopropylamine
448-100-7 - null Intermediate Joint Intermediate Use Only 26-05-2020 View substance registered dossier
(4-fluorophenyl)-isopropylamine
448-100-7 - null NONS Individual Tonnage Data Confidential 25-08-2020 View substance registered dossier
(4-hydrazinophenyl)-N-methylmethanesulfonamide hydrochloride
406-090-1 81880-96-8 null NONS Individual Tonnage Data Confidential 02-04-2020 View substance registered dossier
(4-methoxybiphenyl-3-yl)hydrazine hydrochloride
924-885-6 - null Intermediate Joint Intermediate Use Only 30-04-2020 View substance registered dossier
(4-Methoxyphenyl)diphenylsulfoniumnonaflate
435-570-3 - null NONS Individual Tonnage Data Confidential 30-03-2020 View substance registered dossier
(4-methylphenyl)mesitylene sulfonate
407-530-5 67811-06-7 null NONS Individual Tonnage Data Confidential 26-05-2020 View substance registered dossier
(4-nitrophenyl)methanesulfonyl chloride
609-806-2 4025-75-6 null Intermediate Individual Intermediate Use Only 24-05-2020 View substance registered dossier
(4-nitrophenyl)methyl [6R,(6α,7β)]-[3-hydroxy-5,8-dioxo-7-(phenoxyacetylamino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate]
411-820-7 - null NONS Individual Tonnage Data Confidential 02-04-2020 View substance registered dossier
(4-nonylphenoxy)acetic acid
221-486-2 3115-49-9 Active Full Joint ≥ 100 to < 1 000 tonnes 04-07-2014 View substance registered dossier
(4-phenylbutyl)phosphinic acid
420-450-5 86552-32-1 Active Intermediate Joint Intermediate use only 09-12-2013 View substance registered dossier
(4-pyridylmethyl)amine
223-092-6 3731-53-1 null Intermediate Joint Intermediate Use Only 13-05-2020 View substance registered dossier
(4-pyridylthio)acetyl chloride hydrochloride
248-348-4 27230-51-9 null Intermediate Joint Intermediate Use Only 16-07-2020 View substance registered dossier
(4-Sulfamoylpheny)hydrazine monohydrochloride
479-480-2 17852-52-7 Active Full Joint ≥ 10 to < 100 tonnes 18-09-2017 View substance registered dossier
(4-Sulfamoylpheny)hydrazine monohydrochloride
479-480-2 17852-52-7 null NONS Individual Tonnage Data Confidential 02-04-2020 View substance registered dossier
(4-Sulfamoylpheny)hydrazine monohydrochloride
479-480-2 17852-52-7 null Intermediate Joint Intermediate Use Only 26-05-2020 View substance registered dossier
(4-tert-butyl-2,6-dimethylphenyl)acetonitrile
284-183-4 84803-57-6 null Intermediate Joint Intermediate Use Only 14-04-2020 View substance registered dossier
(4-vinylphenyl)methyl-2-[(1Z)-1-aza-3-methyl-2-(4-methylthiophenyl)-3-morpholin-4-ylbut-1-enyloxy]acetate
453-050-4 - Active NONS Individual Tonnage data confidential 04-02-2011 View substance registered dossier
(4aR*, 8aR*)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-6H-benzofuro[3a,3,2-ef] [2]benzazepin-6-one hydrochloride (1:1)
700-867-1 - null Full Joint 0 - 10 tonnes per annum 16-07-2020 View substance registered dossier
(4aR*,8aR*)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one hydrochloride
439-750-2 183487-56-1 Active Full Joint ≥ 1 to < 10 tonnes 23-05-2018 View substance registered dossier
(4aR*,8aR*)-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one
428-690-2 1668-86-6 Cease Manufacture NONS Individual Cease manufacture 23-11-2010 View substance registered dossier
(4aR,4bS,6aS,7aS,8aS,8bR,8cR)-2-methoxy-4a,6a-dimethyl-4,4a,4b,5,6,6a,7a,8,8a,8b,8c,9-dodecahydrocyclopropa[4,5]cyclopenta[1,2-a]phenanthren-7(3H)-one
607-934-3 26441-40-7 Active Intermediate Joint Intermediate use only 29-04-2020 View substance registered dossier
(4aR,4bS,6aS,7S,7aS,8aS,8bR,8cR)-7-[2-(1,3-dioxolan-2-yl)ethyl]-2-methoxy-4a,6a-dimethyl-3,4,4a,4b,5,6,6a,7,7a,8,8a,8b,8c,9-tetradecahydrocyclopropa[4,5]cyclopenta[1,2-a]phenanthren-7-ol
618-226-9 889652-22-6 Active Intermediate Joint Intermediate use only 05-05-2020 View substance registered dossier
(4aR,4bS,6aS,7S,7aS,8aS,8bS,8cR)-5`-methoxy-4a,6a-dimethyl-4,4`,4a,4b,5`,6,6a,7a,8,8a,8b,8c-dodecahydro-3H,3`H-spiro[cyclopropa[4,5]cyclopenta[1,2-a]phenathrene-7,2`-furan]-2(5H)-one
695-294-6 71136-60-2 Active Intermediate Joint Intermediate use only 30-04-2020 View substance registered dossier
(4aR,4bS,6aS,9aS,9bR,11aR)-4a,6a-Dimethyltetradecahydro-1H-indeno[5,4-f]quinoline-2,7-dione
616-323-0 76318-69-9 Active Intermediate Joint Intermediate use only 14-06-2016 View substance registered dossier
(4aR,5S,8R,8aS)-1,2,3,4,4a,5,8,8a-octahydro-1,4:5,8-dimethanonaphthalene
700-678-4 - null Full Individual 100 - 1 000 tonnes per annum 22-07-2020 View substance registered dossier
(4aS-cis-)-6-benzyl-octahydropyrrolo[3.4-b]pyridine
425-930-8 151213-39-7 null NONS Individual Tonnage Data Confidential 02-04-2020 View substance registered dossier
(4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one
939-401-9 - Active Full Joint ≥ 100 to < 1 000 tonnes 03-11-2020 View substance registered dossier
(4E)-4-[3-(2,5-dichloro-4,6-dimethylpyridin-3-yl)-2H-1,2,4-oxadiazol-5-ylidene]-2-methoxy-6-nitrocyclohexa-2,5-dien-1-one
941-406-6 1391712-50-7 null Intermediate Joint Intermediate Use Only 25-05-2020 View substance registered dossier
(4E)-4-methyl-5-(4-methylphenyl)pent-4-enal
700-748-4 1226911-69-8 null Full Joint 1 - 10 tonnes per annum 25-05-2020 View substance registered dossier
(4E)-5-cyclohexyl-2,4-dimethylpent-4-enal
947-579-4 1449104-34-0 Active Full Joint ≥ 1 to < 10 tonnes 08-12-2020 View substance registered dossier
(4E)-N-hydroxy-1,2-benzoxathiin-4(3H)-imine 2,2-dioxide
611-875-9 597563-86-5 null Intermediate Joint Intermediate Use Only 24-05-2020 View substance registered dossier
(4R)-1-(tert-butoxycarbonyl)-4-hydroxy-L-proline
604-011-7 13726-69-7 null Intermediate Joint Intermediate Use Only 05-08-2020 View substance registered dossier
(4R)-2-(1-butoxyethoxy)-4-isopropyl-1-methylenecyclohexane
944-221-9 1429469-15-7 null Intermediate Joint Intermediate Use Only 25-05-2020 View substance registered dossier
(4R)-2-oxo-1,3-oxazolidine-4-carboxylic acid
849-166-3 83841-00-3 null Intermediate Joint Intermediate Use Only 25-06-2020 View substance registered dossier
(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;N,N-diethylethanamine
926-346-0 - null Intermediate Joint Intermediate Use Only 24-05-2020 View substance registered dossier
(4R)-4-methyl-1,3-dioxolan-2-one
437-320-9 - null NONS Individual Tonnage Data Confidential 30-03-2020 View substance registered dossier
(4R)-6-amino-N,N,4-trimethyl-1,4-dihydro-1,3,5-triazin-2-aminium (2R,3R)-3-carboxy-2,3-dihydroxypropanoate
942-402-7 - null Intermediate Joint Intermediate Use Only 25-05-2020 View substance registered dossier
(4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one
433-160-9 - Active Full Joint ≥ 1 to < 10 tonnes 18-08-2020 View substance registered dossier
(4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one
433-160-9 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(4R,12aS)-7-Benzyloxy-N-[(2,4-difluorophenyl)methyl]-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
809-887-6 1206102-11-5 null Intermediate Individual Intermediate Use Only 25-05-2020 View substance registered dossier
(4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
809-888-1 1051375-16-6 null Intermediate Individual Intermediate Use Only 25-05-2020 View substance registered dossier
(4R,6R)-4-Hydroxy-2,2,6-trimethylcyclohexanone / 60046-50-6
700-052-0 60046-50-6 Active Intermediate Joint Intermediate use only 20-11-2019 View substance registered dossier
(4R,6R)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-Dioxane-4-acetic acid 1,1-dimethylethyl ester
700-258-0 125971-95-1 Active Intermediate Individual Intermediate use only 29-09-2010 View substance registered dossier
(4R,6R)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-Dioxane-4-acetic acid 1,1-dimethylethyl ester
700-258-0 125971-95-1 Active Intermediate Individual Intermediate use only 27-10-2010 View substance registered dossier
(4R,6R)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-Dioxane-4-acetic acid 1,1-dimethylethyl ester
700-258-0 125971-95-1 Active Intermediate Individual Intermediate use only 04-03-2011 View substance registered dossier
(4R,6R)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-Dioxane-4-acetic acid 1,1-dimethylethyl ester
700-258-0 125971-95-1 Active Intermediate Joint Intermediate use only 23-07-2020 View substance registered dossier
(4R,6S)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol
604-572-8 147128-77-6 null Intermediate Joint Intermediate Use Only 30-04-2020 View substance registered dossier
(4S)-1-(tert-butoxycarbonyl)-4-(hydroxymethyl)-L-proline
812-482-7 1643468-66-9 null Intermediate Individual Intermediate Use Only 25-05-2020 View substance registered dossier
(4S)-1-(tert-butoxycarbonyl)-4-(methoxymethyl)-L-proline
807-416-9 1378388-16-9 null Intermediate Joint Intermediate Use Only 25-05-2020 View substance registered dossier
(4S)-1-[(2S)-3-(benzoylthio)-2-methyl-1-oxopropyl]-4-(phenylthio)-L-proline potassium salt
617-274-8 81938-42-3 null Intermediate Individual Intermediate Use Only 24-05-2020 View substance registered dossier
(4S)-2-(4-bromophenyl)-4-isopropyl-3-pentanoyl-1,3-oxazolidin-5-one
700-586-4 852212-81-8 Active Intermediate Individual Intermediate use only 10-05-2011 View substance registered dossier
(4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone
848-798-7 272778-12-8 Active Intermediate Joint Intermediate use only 15-06-2020 View substance registered dossier
(4S)-3-carbamoyl-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridin-1-ium (2S,3S)-2,3-bis(benzoyloxy)-3-carboxypropanoate
947-346-7 - null Intermediate Individual Intermediate Use Only 02-04-2020 View substance registered dossier
(4S)-4-(2-Chlorophenyl)-2-hydroxy-5,5-dimethyl-1,3,2-dioxaphosphinane 2-oxide
623-314-5 98674-86-3 null Intermediate Joint Intermediate Use Only 24-05-2020 View substance registered dossier
(4S)-4-(phenylthio)-L-proline
617-252-8 81653-77-2 null Intermediate Joint Intermediate Use Only 26-05-2020 View substance registered dossier
(4S)-4-cyclohexyl-L-proline
600-406-3 103201-78-1 Active Intermediate Individual Intermediate use only 24-02-2010 View substance registered dossier
(4S)-4-hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
807-123-6 154127-42-1 null Intermediate Individual Intermediate Use Only 25-05-2020 View substance registered dossier
(4S,4aR,5aR,6R,6aR,6bS,7S,9aS,11aS,11bR)-6-hydroxy-9a,11b-dimethyl-9-oxohexadeca hydrocyclopenta[1,2]phenanthro[8a,9-b]oxirene-4,7-diyl bis(2,2-dimethylpropanoate)
825-705-8 1235460-56-6 Active Intermediate Joint Intermediate use only 17-07-2018 View substance registered dossier
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1)
940-053-5 - Active Intermediate Joint Intermediate use only 19-01-2017 View substance registered dossier
(4S,4aS,5aR,12aR)-11a-halo-4-(dialkylamino)-3,10,12a-trihydroxy-1,11,12-trioxo-1,4,4a,5,5a,6,11,11a,12,12a-carbopolycyclyl-2-carboxamide hydrohalide
917-355-0 - Active Intermediate Individual Intermediate use only 21-05-2018 View substance registered dossier
(4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-7-[[methoxy(methyl)amino]methyl]-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide
811-441-0 1035654-66-0 null Intermediate Joint Intermediate Use Only 25-05-2020 View substance registered dossier
(4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide dihydrochloride
611-780-2 59046-78-5 null Intermediate Individual Intermediate Use Only 24-05-2020 View substance registered dossier
(4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide; 4-chlorobenzene-1-sulfonic acid
618-775-4 916439-93-5 null Intermediate Joint Intermediate Use Only 30-04-2020 View substance registered dossier
(4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
617-177-0 808-26-4 null Intermediate Joint Intermediate Use Only 30-04-2020 View substance registered dossier
(4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide p-toluenesulfonate
947-931-7 - null Intermediate Individual Intermediate Use Only 25-05-2020 View substance registered dossier
(4S,4aS,5aR,12aS)-9-amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride (1:1)
604-710-7 149934-21-4 Active Intermediate Joint Intermediate use only 12-08-2019 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active (3Z)-hex-3-en-1-yl 2-methylprop-2-en-1-yl ether 439-790-0 292605-05-1 2013 View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active (3Z)-hex-3-en-1-yl cyclopropanecarboxylate 425-200-9 - 2012 View substance registered dossier
- - - - (3Z)-hex-3-en-1-yl cyclopropanecarboxylate 425-200-9 - - View substance registered dossier
Farmabios Spa Via Pavia, 1 27027 Gropello Cairoli PV Italy - - (3α,5β,7β)-3,7-Dihydroxy-24-norcholane-23-nitrile 828-107-5 118316-12-4 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (3β)-17-(1,1,1-trifluoromethanesulfonate)-Androsta-5,16-diene-3,17-diol, 3-(2,2,2-trifluoroacetate) 840-627-4 1802323-89-2 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20090 RODANO Milano Italy - - (3β)-3-[(2,2,2-trifluoroacetyl)oxy]-Androst-5-en-17-one 840-626-9 3798-17-2 - View substance registered dossier
Indena S.p.A. Viale Ortles, 12 20139 Milan Italy Italy Active (3β,20β)-3-acetoxy-11-oxoolean-12-en-29-oic acid 228-475-1 6277-14-1 2019 View substance registered dossier
DSM Nutritional Products France SAS 1 boulevard d'Alsace F-68128 Village-Neuf France - - (3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-yl butyrate 250-567-5 31316-20-8 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active (4'-methyl-3-fluoro[1,1'-biphenyl]-4-yl)-boronic acid 813-651-8 1698890-39-9 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain - - (4,5-dibromo-1H-pyrrol-2-yl)(phenyl)methanone 700-338-5 50372-61-7 - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain - - (4,5-dibromo-1H-pyrrol-2-yl)(phenyl)methanone 700-338-5 50372-61-7 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active (4-(1-methylethyl)phenyl)-(4-methylphenyl)iodonium tetrakis(pentafluorophenyl)borate (1-) 422-960-3 178233-72-2 - View substance registered dossier
ELKEM SILICONES FRANCE S.A.S. Immeuble DANICA 21, Avenue Georges Pompidou 69003 Lyon France France Active (4-(1-methylethyl)phenyl)-(4-methylphenyl)iodonium tetrakis(pentafluorophenyl)borate (1-) 422-960-3 178233-72-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (4-(1-methylethyl)phenyl)-(4-methylphenyl)iodonium tetrakis(pentafluorophenyl)borate (1-) 422-960-3 178233-72-2 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy - - (4-(3,4-dichloro-phenyl)-3,4-dihydro-2H-naphthalen-1-ylidene)-methyl-amide 455-240-2 - - View substance registered dossier
- - - - (4-(4-(4-dimethylaminobenzyliden-1-yl)-3-methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid 410-430-4 117573-89-4 - View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active (4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone 613-265-8 63590-64-7 2018 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden - - (4-(4-aminophenyl)(4-iminocyclohexa-2,5-dienylidene)methyl)-2-methylaniline hydrochloride 211-189-6 632-99-5 - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy - - (4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-phenylamino)-acetic acid ethyl ester 927-587-4 872728-83-1 - View substance registered dossier
AllessaProduktion GmbH Alt-Fechenheim 34 60386 Frankfurt am Main Germany - - (4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-phenylamino)-acetic acid ethyl ester 927-587-4 872728-83-1 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazole-3-yl)phenylamino)acetic acid 460-450-2 872728-82-0 - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active (4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazole-3-yl)phenylamino)acetic acid 460-450-2 872728-82-0 2013; 2016 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazole-3-yl)phenylamino)acetic acid 460-450-2 872728-82-0 2012; 2014; 2016 View substance registered dossier
AllessaProduktion GmbH Alt-Fechenheim 34 60386 Frankfurt am Main Germany Germany Active (4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazole-3-yl)phenylamino)acetic acid 460-450-2 872728-82-0 2012; 2019 View substance registered dossier
- - - - (4-(6-diethylamino-2-methylpyridin-3-yl)imino-4,5-dihydro-3-methyl-1-(4-methylphenyl)-1H-pyrazol-5-one 427-070-9 - - View substance registered dossier
- - - - (4-6) PEPTIDE 427-550-8 - - View substance registered dossier
United Initiators GmbH Dr. Gustav-Adolph-Str. 3 D-82049 Pullach Bavaria Germany - - (4-acetamido-2,2,6,6-tetramethyl-1-piperidinyl)oxidanyl; N-(2,2,6,6-tetramethyl-1-oxylpiperidin-4-yl)acetamide 423-840-3 14691-89-5 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany - - (4-acetamido-2,2,6,6-tetramethyl-1-piperidinyl)oxidanyl; N-(2,2,6,6-tetramethyl-1-oxylpiperidin-4-yl)acetamide 423-840-3 14691-89-5 - View substance registered dossier
MSD International GmbH Ballydine - Kilsheelan 0 Clonmel Ireland - - (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid;hydrate 680-378-7 138624-11-0 - View substance registered dossier
Menadiona SL Pol Ind Mas Puigvert, Ctra Nacional II Km 680, 5 08389 Palafolls Barcelona Spain Spain Active (4-amino-2-chloro-5-methylphenyl)(4-chlorophenyl)acetonitrile 262-792-6 61437-85-2 - View substance registered dossier
Globalquimia, S.L.U. Avenida Diagonal, 519, 1º 1ª 08029 Barcelona Spain Spain Spain Active (4-amino-2-chloro-5-methylphenyl)(4-chlorophenyl)acetonitrile 262-792-6 61437-85-2 - View substance registered dossier
- - - - (4-aminophenyl)-N-methylmethylenesulfonamide hydrochloride 406-010-5 88918-84-7 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany - - (4-benzylpiperazin-1-yl)(cyclopropyl)methanone hydrochloride 816-907-7 1294454-93-5 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active (4-butoxy-2,3-difluorophenyl)boronic acid 692-793-0 156487-12-6 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (4-carboxybutyl)triphenylphosphonium bromide 241-782-5 17814-85-6 - View substance registered dossier
DOW AGROSCIENCES LIMITED CPC2 Capital Park, Fulbourn Cambridge CB21 5XE Cambridgeshire United Kingdom - - (4-chloro-2-fluoro-3-methoxyphenyl)boronic acid 696-001-4 944129-07-1 - View substance registered dossier
Derivados Quimicos SAU Strada Rivoltana km6/7 20053 Rodano (Milano) Lombardia Spain Spain Cease Manufacture (4-chloro-2-fluorophenyl)acetonitrile 642-783-7 75279-53-7 2020 View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France - - (4-Chloro-3-(4-ethoxybenzyl)phenyl)((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanone 695-300-7 1103738-30-2 - View substance registered dossier
Derivados Químicos S.A. Camino Viejo del Pliego s/n 30820 Alcantarilla Murcia Spain - - (4-chlorophenyl)(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol 814-124-5 133545-64-9 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (4-chlorophenyl)hydrazine 214-029-3 1073-69-4 2010 View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid (4-chlorophenyl)hydrazine 214-029-3 1073-69-4 2018 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid 826-639-2 1817776-86-5 - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active (4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid 826-639-2 1817776-86-5 - View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France - - (4-ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane 405-020-7 105024-66-6 - View substance registered dossier
Albemarle Germany GmbH Industriepark Höchst Gebäude G 879 65926 Frankfurt Germany Germany Active (4-fluorobenzenide)magnesium(1+)bromide 627-087-3 352-13-6 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany - - (4-fluorophenyl)-isopropylamine 448-100-7 - - View substance registered dossier
[Confidential] [Confidential] - - (4-fluorophenyl)-isopropylamine 448-100-7 - - View substance registered dossier
ACETO GmbH Hans-Henny-Jahnn-Weg 51 22085 Hamburg Germany - - (4-fluorophenyl)-isopropylamine 448-100-7 - - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany - - (4-fluorophenyl)-isopropylamine 448-100-7 - - View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom - - (4-hydrazinophenyl)-N-methylmethanesulfonamide hydrochloride 406-090-1 81880-96-8 - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic - - (4-methoxybiphenyl-3-yl)hydrazine hydrochloride 924-885-6 - - View substance registered dossier
- - - - (4-Methoxyphenyl)diphenylsulfoniumnonaflate 435-570-3 - - View substance registered dossier
- - - - (4-methylphenyl)mesitylene sulfonate 407-530-5 67811-06-7 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France - - (4-nitrophenyl)methanesulfonyl chloride 609-806-2 4025-75-6 - View substance registered dossier
- - - - (4-nitrophenyl)methyl [6R,(6α,7β)]-[3-hydroxy-5,8-dioxo-7-(phenoxyacetylamino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate] 411-820-7 - - View substance registered dossier
BASF Lampertheim GmbH Chemiestrasse 22 68619 Lampertheim Germany Germany Active (4-nonylphenoxy)acetic acid 221-486-2 3115-49-9 2014 View substance registered dossier
BASF Performance Products France SA 49, Avenue Georges Pompidou 92593 Levallois-Perret Cedex France France Cease Manufacture (4-nonylphenoxy)acetic acid 221-486-2 3115-49-9 2015 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (4-nonylphenoxy)acetic acid 221-486-2 3115-49-9 - View substance registered dossier
Corden Pharma Latina S.p.A. Via del Murillo Km 2, 800 IT04013 Sermoneta (LT) Lazio Italy Italy Cease Manufacture (4-phenylbutyl)phosphinic acid 420-450-5 86552-32-1 2017 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (4-phenylbutyl)phosphinic acid 420-450-5 86552-32-1 - View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France - - (4-pyridylmethyl)amine 223-092-6 3731-53-1 - View substance registered dossier
Corden Pharma Latina S.p.A. Via del Murillo Km 2, 800 IT04013 Sermoneta (LT) Lazio Italy - - (4-pyridylthio)acetyl chloride hydrochloride 248-348-4 27230-51-9 - View substance registered dossier
Fine and Performance Chemicals Ltd Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom - - (4-pyridylthio)acetyl chloride hydrochloride 248-348-4 27230-51-9 - View substance registered dossier
AZOINTERNATIONAL OU RAUA 28 10152 TALLINN Estonia - - (4-pyridylthio)acetyl chloride hydrochloride 248-348-4 27230-51-9 - View substance registered dossier
[Confidential] - - - (4-Sulfamoylpheny)hydrazine monohydrochloride 479-480-2 17852-52-7 - View substance registered dossier
Siemsgluss Ibérica, S.A. Pol. Ind. Sant Antoni, parcela 6, nave 2 08620 Sant Vicenç dels Horts Barcelona Spain Spain Active (4-Sulfamoylpheny)hydrazine monohydrochloride 479-480-2 17852-52-7 - View substance registered dossier
- - - - (4-Sulfamoylpheny)hydrazine monohydrochloride 479-480-2 17852-52-7 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany - - (4-Sulfamoylpheny)hydrazine monohydrochloride 479-480-2 17852-52-7 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany - - (4-Sulfamoylpheny)hydrazine monohydrochloride 479-480-2 17852-52-7 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany - - (4-tert-butyl-2,6-dimethylphenyl)acetonitrile 284-183-4 84803-57-6 - View substance registered dossier
FujiFilm Manufacturing Europe BV Oudenstaart 1 5047 TK Tilburg Netherlands Netherlands Active (4-vinylphenyl)methyl-2-[(1Z)-1-aza-3-methyl-2-(4-methylthiophenyl)-3-morpholin-4-ylbut-1-enyloxy]acetate 453-050-4 - 2011 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium - - (4aR*, 8aR*)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-6H-benzofuro[3a,3,2-ef] [2]benzazepin-6-one hydrochloride (1:1) 700-867-1 - - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium - - (4aR*, 8aR*)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-6H-benzofuro[3a,3,2-ef] [2]benzazepin-6-one hydrochloride (1:1) 700-867-1 - - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (4aR*,8aR*)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one hydrochloride 439-750-2 183487-56-1 2010; 2012; 2018 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (4aR*,8aR*)-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one 428-690-2 1668-86-6 2019 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (4aR,4bS,6aS,7aS,8aS,8bR,8cR)-2-methoxy-4a,6a-dimethyl-4,4a,4b,5,6,6a,7a,8,8a,8b,8c,9-dodecahydrocyclopropa[4,5]cyclopenta[1,2-a]phenanthren-7(3H)-one 607-934-3 26441-40-7 2020 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (4aR,4bS,6aS,7S,7aS,8aS,8bR,8cR)-7-[2-(1,3-dioxolan-2-yl)ethyl]-2-methoxy-4a,6a-dimethyl-3,4,4a,4b,5,6,6a,7,7a,8,8a,8b,8c,9-tetradecahydrocyclopropa[4,5]cyclopenta[1,2-a]phenanthren-7-ol 618-226-9 889652-22-6 2020 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (4aR,4bS,6aS,7S,7aS,8aS,8bS,8cR)-5`-methoxy-4a,6a-dimethyl-4,4`,4a,4b,5`,6,6a,7a,8,8a,8b,8c-dodecahydro-3H,3`H-spiro[cyclopropa[4,5]cyclopenta[1,2-a]phenathrene-7,2`-furan]-2(5H)-one 695-294-6 71136-60-2 2020 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (4aR,4bS,6aS,9aS,9bR,11aR)-4a,6a-Dimethyltetradecahydro-1H-indeno[5,4-f]quinoline-2,7-dione 616-323-0 76318-69-9 - View substance registered dossier
Covance Clinical Development SA 163 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 -5 Planta 28050 Madrid Spain - - (4aR,5S,8R,8aS)-1,2,3,4,4a,5,8,8a-octahydro-1,4:5,8-dimethanonaphthalene 700-678-4 - - View substance registered dossier
- - - - (4aS-cis-)-6-benzyl-octahydropyrrolo[3.4-b]pyridine 425-930-8 151213-39-7 - View substance registered dossier
Mare S.p.A. Via Verdi No. 3 20010 Ossona Fraz. Asmonte Italy Italy Active (4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one 939-401-9 - 2020 View substance registered dossier
Solenis Belgium B.V.B.A. Industrieweg 15 3583 Beringen Belgium Belgium Cease Manufacture (4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one 939-401-9 - 2016 View substance registered dossier
Solenis Netherlands B.V. Fascinatio Boulevard 522 2909 VA CAPELLE A/D IJSSEL Netherlands Netherlands Active (4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one 939-401-9 - - View substance registered dossier
Derivados Químicos S.A. Camino Viejo del Pliego s/n 30820 Alcantarilla Murcia Spain - - (4E)-4-[3-(2,5-dichloro-4,6-dimethylpyridin-3-yl)-2H-1,2,4-oxadiazol-5-ylidene]-2-methoxy-6-nitrocyclohexa-2,5-dien-1-one 941-406-6 1391712-50-7 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria - - (4E)-4-[3-(2,5-dichloro-4,6-dimethylpyridin-3-yl)-2H-1,2,4-oxadiazol-5-ylidene]-2-methoxy-6-nitrocyclohexa-2,5-dien-1-one 941-406-6 1391712-50-7 - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France - - (4E)-4-methyl-5-(4-methylphenyl)pent-4-enal 700-748-4 1226911-69-8 - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (4E)-5-cyclohexyl-2,4-dimethylpent-4-enal 947-579-4 1449104-34-0 2020 View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy - - (4E)-N-hydroxy-1,2-benzoxathiin-4(3H)-imine 2,2-dioxide 611-875-9 597563-86-5 - View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy - - (4R)-1-(tert-butoxycarbonyl)-4-hydroxy-L-proline 604-011-7 13726-69-7 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany - - (4R)-1-(tert-butoxycarbonyl)-4-hydroxy-L-proline 604-011-7 13726-69-7 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy - - (4R)-1-(tert-butoxycarbonyl)-4-hydroxy-L-proline 604-011-7 13726-69-7 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany - - (4R)-2-(1-butoxyethoxy)-4-isopropyl-1-methylenecyclohexane 944-221-9 1429469-15-7 - View substance registered dossier
Syngenta Hellas AEBE Anthousas Avenue 153 49 Anthousa - Attiki Greece - - (4R)-2-oxo-1,3-oxazolidine-4-carboxylic acid 849-166-3 83841-00-3 - View substance registered dossier
CABB Oy Kemirantie 1 FI-67701 Kokkola Finland - - (4R)-2-oxo-1,3-oxazolidine-4-carboxylic acid 849-166-3 83841-00-3 - View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy - - (4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;N,N-diethylethanamine 926-346-0 - - View substance registered dossier
- - - - (4R)-4-methyl-1,3-dioxolan-2-one 437-320-9 - - View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom - - (4R)-4-methyl-1,3-dioxolan-2-one 437-320-9 - - View substance registered dossier
EXPANSIA Route d'Avignon BP 6 30390 ARAMON France - - (4R)-6-amino-N,N,4-trimethyl-1,4-dihydro-1,3,5-triazin-2-aminium (2R,3R)-3-carboxy-2,3-dihydroxypropanoate 942-402-7 - - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France - - (4R)-6-amino-N,N,4-trimethyl-1,4-dihydro-1,3,5-triazin-2-aminium (2R,3R)-3-carboxy-2,3-dihydroxypropanoate 942-402-7 - - View substance registered dossier
Visolis, B.V. Urmonderbaan 22 6167 RD Geleen Netherlands Netherlands Active (4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one 433-160-9 - - View substance registered dossier
- - - - (4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one 433-160-9 - - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium - - (4R,12aS)-7-Benzyloxy-N-[(2,4-difluorophenyl)methyl]-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide 809-887-6 1206102-11-5 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium - - (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide 809-888-1 1051375-16-6 - View substance registered dossier
[Confidential] - - - (4R,6R)-4-Hydroxy-2,2,6-trimethylcyclohexanone / 60046-50-6 700-052-0 60046-50-6 - View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active (4R,6R)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-Dioxane-4-acetic acid 1,1-dimethylethyl ester 700-258-0 125971-95-1 - View substance registered dossier
Lek Pharmaceuticals d.d. Verovskova 57 1526 Ljubljana Slovenia Slovenia Active (4R,6R)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-Dioxane-4-acetic acid 1,1-dimethylethyl ester 700-258-0 125971-95-1 2008; 2010 View substance registered dossier
Saneca Pharmaceuticals a.s. Nitrianska 100 92027 Hlohovec Slovakia Slovakia Active (4R,6R)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-Dioxane-4-acetic acid 1,1-dimethylethyl ester 700-258-0 125971-95-1 2011 View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (4R,6R)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-Dioxane-4-acetic acid 1,1-dimethylethyl ester 700-258-0 125971-95-1 2018 View substance registered dossier
DKSH France S.A. 1475 Quai du Rhone 01702 Miribel France France Active (4R,6R)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-Dioxane-4-acetic acid 1,1-dimethylethyl ester 700-258-0 125971-95-1 - View substance registered dossier
ORIL INDUSTRIE 13 rue Auguste Desgenétais 76210 BOLBEC France France Active (4R,6R)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-Dioxane-4-acetic acid 1,1-dimethylethyl ester 700-258-0 125971-95-1 2019; 2020 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (4R,6R)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-Dioxane-4-acetic acid 1,1-dimethylethyl ester 700-258-0 125971-95-1 - View substance registered dossier
DUKE CHEM, S.A. Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain - - (4R,6S)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol 604-572-8 147128-77-6 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy - - (4S)-1-(tert-butoxycarbonyl)-4-(hydroxymethyl)-L-proline 812-482-7 1643468-66-9 - View substance registered dossier
Gilead Sciences Ireland UC IDA Business &Technology Park Carrigtohill Cork Cork Ireland - - (4S)-1-(tert-butoxycarbonyl)-4-(methoxymethyl)-L-proline 807-416-9 1378388-16-9 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy - - (4S)-1-(tert-butoxycarbonyl)-4-(methoxymethyl)-L-proline 807-416-9 1378388-16-9 - View substance registered dossier
Derivados Químicos S.A. Camino Viejo del Pliego s/n 30820 Alcantarilla Murcia Spain - - (4S)-1-(tert-butoxycarbonyl)-4-(methoxymethyl)-L-proline 807-416-9 1378388-16-9 - View substance registered dossier
LusoChimica S.p.A. Via Giotto, 9 23871 Lomagna (Lecco) Italy - - (4S)-1-[(2S)-3-(benzoylthio)-2-methyl-1-oxopropyl]-4-(phenylthio)-L-proline potassium salt 617-274-8 81938-42-3 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active (4S)-2-(4-bromophenyl)-4-isopropyl-3-pentanoyl-1,3-oxazolidin-5-one 700-586-4 852212-81-8 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone 848-798-7 272778-12-8 2020 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany - - (4S)-3-carbamoyl-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridin-1-ium (2S,3S)-2,3-bis(benzoyloxy)-3-carboxypropanoate 947-346-7 - - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland - - (4S)-4-(2-Chlorophenyl)-2-hydroxy-5,5-dimethyl-1,3,2-dioxaphosphinane 2-oxide 623-314-5 98674-86-3 - View substance registered dossier
Giusto Faravelli via medardo rosso , 8 20159 milano italy Italy - - (4S)-4-(phenylthio)-L-proline 617-252-8 81653-77-2 - View substance registered dossier
Phardiag Ltd 70 Sir John Rogersons Quay 4 Dublin Ireland - - (4S)-4-(phenylthio)-L-proline 617-252-8 81653-77-2 - View substance registered dossier
LusoChimica S.p.A. Via Giotto, 9 23871 Lomagna (Lecco) Italy - - (4S)-4-(phenylthio)-L-proline 617-252-8 81653-77-2 - View substance registered dossier
Amino Chemicals Ltd Industrial Estate, A61 MRS3000 Marsa Malta Malta Active (4S)-4-cyclohexyl-L-proline 600-406-3 103201-78-1 - View substance registered dossier
Fine and Performance Chemicals Ltd Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom - - (4S)-4-hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide 807-123-6 154127-42-1 - View substance registered dossier
CHEMO BIOSYNTHESIS SRL VIALE ISONZO, 8 20135 MILANO Italy Italy Active (4S,4aR,5aR,6R,6aR,6bS,7S,9aS,11aS,11bR)-6-hydroxy-9a,11b-dimethyl-9-oxohexadeca hydrocyclopenta[1,2]phenanthro[8a,9-b]oxirene-4,7-diyl bis(2,2-dimethylpropanoate) 825-705-8 1235460-56-6 - View substance registered dossier
Hovione FarmaCiencia SA Sete Casas 2674-506 Loures Portugal Portugal Active (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1) 940-053-5 - 2017 View substance registered dossier
Hovione Limited Loughbeg not available Ringaskiddy County Cork Ireland Ireland Active (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1) 940-053-5 - 2017 View substance registered dossier
[Confidential] - - - (4S,4aS,5aR,12aR)-11a-halo-4-(dialkylamino)-3,10,12a-trihydroxy-1,11,12-trioxo-1,4,4a,5,5a,6,11,11a,12,12a-carbopolycyclyl-2-carboxamide hydrohalide 917-355-0 - - View substance registered dossier
Amri Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy - - (4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-7-[[methoxy(methyl)amino]methyl]-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide 811-441-0 1035654-66-0 - View substance registered dossier
[Confidential] [Confidential] - - (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide dihydrochloride 611-780-2 59046-78-5 - View substance registered dossier
Amri Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy - - (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide; 4-chlorobenzene-1-sulfonic acid 618-775-4 916439-93-5 - View substance registered dossier
Cipan - Companhia Industrial Produtora de Antibióticos Rua da Estação, 42 Vala do Carregado 2600-726 Castanheira do Ribatejo Lisboa Portugal - - (4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide 617-177-0 808-26-4 - View substance registered dossier
Amri Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy - - (4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide 617-177-0 808-26-4 - View substance registered dossier
Hovione FarmaCiencia SA Sete Casas 2674-506 Loures Portugal - - (4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide 617-177-0 808-26-4 - View substance registered dossier
Cipan - Companhia Industrial Produtora de Antibióticos Rua da Estação, 42 Vala do Carregado 2600-726 Castanheira do Ribatejo Lisboa Portugal - - (4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide p-toluenesulfonate 947-931-7 - - View substance registered dossier
Amri Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (4S,4aS,5aR,12aS)-9-amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride (1:1) 604-710-7 149934-21-4 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (4S,4aS,5aR,12aS)-9-amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride (1:1) 604-710-7 149934-21-4 2013; 2018; 2019 View substance registered dossier

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