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Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The REACH Registered substance portal was updated on 9th November 2020; the REACH registered factsheets were further updated on 21st December 2020. Details of the improvements can be found at Dissemination Platform Updates. Reprocessing the entire dataset is ongoing since 21 December 2020. ECHA is making all possible efforts to make the improvements and additional data visible with the shortest delay.
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
Last updated 20 January 2021. Database contains 23121 unique substances and contains information from 101751 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
Select total tonnage band range:

0

Infinite



Uses and exposure
Life cycle:
  • Consumer Uses
  • Article service life
  • Widespread uses by professional workers
  • Formulation or re-packing
  • Uses at industrial sites
  • Manufacture
Category:
Details
(2R)-3-chloropropane-1,2-diol
611-463-9 57090-45-6 null Intermediate Joint Intermediate Use Only 30-04-2020 View substance registered dossier
(2R)-3-cyano-2-hydroxy-N,N,N-trimethylpropan-1-aminium chloride
700-669-5 2788-28-5 null Intermediate Joint Intermediate Use Only 22-05-2020 View substance registered dossier
(2R)-4-hydroxybutan-2-aminium (2S)-hydroxy(phenyl)acetate
810-156-9 1236049-43-6 Active Intermediate Individual Intermediate use only 15-02-2016 View substance registered dossier
(2R)-6-fluoro-2-(oxiran-2-yl)chromane
930-890-4 - Active Full Joint ≥ 1 to < 10 tonnes 03-06-2019 View substance registered dossier
(2R)-6-fluorochromane-2-carboxylic acid
810-841-2 129101-37-7 null Intermediate Individual Intermediate Use Only 25-05-2020 View substance registered dossier
(2R)-acetoxy(phenyl)acetic acid
610-598-0 51019-43-3 null Intermediate Joint Intermediate Use Only 30-04-2020 View substance registered dossier
(2R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide - (2R,3R)-2,3-dihydroxysuccinic acid - propan-2-ol (2:1:1)
947-841-8 - null Intermediate Individual Intermediate Use Only 25-05-2020 View substance registered dossier
(2R*,3S*)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol (1R)-10-camphorsulfonate
427-100-0 - null NONS Individual Tonnage Data Confidential 02-04-2020 View substance registered dossier
(2R*,3S*)-2-acetyl-1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethylnaphthalene; reaction mass of: (1R*,2S*)-2-acetyl-1,2,3,4,5,6,7,8-octahydro-1,2,8,8-tetramethylnaphthalene
425-570-1 - null NONS Individual Tonnage Data Confidential 30-03-2020 View substance registered dossier
(2R,2'R)-3,3'-disulfanediylbis(2-((S)-2-aminopropanamido)propanoic acid)
850-779-3 115888-13-6 Active Full Joint ≥ 0 to < 10 tonnes 03-08-2020 View substance registered dossier
(2R,3R)-2,3-bis(acetyloxy)butanedioic acid - 3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine (1:1)
920-610-9 - Active Intermediate Joint Intermediate use only 12-04-2017 View substance registered dossier
(2R,3R)-2,3-bis[(4-methoxybenzoyl)oxy]butanedioic acid
672-585-6 50583-51-2 null Intermediate Individual Intermediate Use Only 24-05-2020 View substance registered dossier
(2R,3R)-2,3-Dihydroxybutanedioic acid--(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide (1/1)
947-840-2 - null Intermediate Individual Intermediate Use Only 25-05-2020 View substance registered dossier
(2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol methanesulfonate
815-196-0 1175536-50-1 null Intermediate Joint Intermediate Use Only 25-05-2020 View substance registered dossier
(2R,3R)-3-((R)-1-(tert-butyldimethylsiloxy)ethyl)-4-oxoazetidin-2-yl acetate
408-050-9 76855-69-1 null NONS Individual Tonnage Data Confidential 02-04-2020 View substance registered dossier
(2R,3R)-3-((R)-1-(tert-butyldimethylsiloxy)ethyl)-4-oxoazetidin-2-yl acetate
408-050-9 76855-69-1 Active Intermediate Individual Intermediate use only 20-09-2012 View substance registered dossier
(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide
609-299-8 368421-58-3 null Intermediate Individual Intermediate Use Only 24-05-2020 View substance registered dossier
(2R,3R)-3-(3-(Benzyloxy)phenyl-2-methylpentanoic acid
805-624-4 1367878-84-9 Active Intermediate Joint Intermediate use only 28-05-2020 View substance registered dossier
(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate
479-560-7 989-51-5 null NONS Individual Tonnage Data Confidential 30-03-2020 View substance registered dossier
(2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol [(1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonic acid
948-743-8 - null Intermediate Joint Intermediate Use Only 25-05-2020 View substance registered dossier
(2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl L-valinate dihydrochloride
948-534-1 1639208-51-7 null Intermediate Joint Intermediate Use Only 25-05-2020 View substance registered dossier
(2R,3R,4R)-3,4-Bis(benzyloxy)-2-((benzyloxy)methyl)-5-methoxytetrahydrofuran
857-987-3 64363-77-5 Active Intermediate Joint Intermediate use only 01-09-2020 View substance registered dossier
(2R,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(phenylmethoxy)-5-(phenylmethoxymethyl)oxolane-2-carbonitrile
856-564-0 1355357-49-1 null Intermediate Joint Intermediate Use Only 02-08-2020 View substance registered dossier
(2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-(benzoyloxymethyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate
807-677-9 817204-32-3 Cease Manufacture Intermediate Individual Cease manufacture 12-01-2016 View substance registered dossier
(2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-(benzoyloxymethyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate
807-677-9 817204-32-3 null Intermediate Joint Intermediate Use Only 25-05-2020 View substance registered dossier
(2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol
606-239-2 19130-96-2 Active Intermediate Individual Intermediate use only 17-10-2012 View substance registered dossier
(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile
857-885-9 1191237-69-0 null Intermediate Joint Intermediate Use Only 12-10-2020 View substance registered dossier
(2R,3R,4S,5R)-2-(acetoxymethyl)-6-oxotetrahydro-2H-pyran-3,4,5-triyl triacetate
612-107-5 61259-48-1 null Intermediate Individual Intermediate Use Only 24-05-2020 View substance registered dossier
(2R,3R,4S,5R)-2-(acetoxymethyl)-6-oxotetrahydro-2H-pyran-3,4,5-triyl triacetate
612-107-5 61259-48-1 null Intermediate Individual Intermediate Use Only 24-05-2020 View substance registered dossier
(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-12,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulfonate
927-721-1 - Active Intermediate Joint Intermediate use only 19-06-2020 View substance registered dossier
(2R,3S)-butane-2,3-diol
823-920-1 5341-95-7 Active Full Joint ≥ 1 to < 10 tonnes 02-05-2019 View substance registered dossier
(2R,3S)-N-(3-amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-nitrobenzenesulfonamide hydrochloride
425-260-6 244634-31-9 Active Intermediate Joint Intermediate use only 10-04-2012 View substance registered dossier
(2R,3S,4R)-2-(Hydroxymethyl)-5-methoxytetrahydrofuran-3,4-diol
857-672-0 13039-63-9 Active Intermediate Joint Intermediate use only 01-09-2020 View substance registered dossier
(2R,3S,4R,5R)-2,3,4,6-tetrakis(benzyloxy)-5-hydroxy-1-(4-methylpiperazin-1-yl) hexan-1-one
829-550-7 1431329-04-2 null Intermediate Individual Intermediate Use Only 25-05-2020 View substance registered dossier
(2R,3S,4R,5R)-2,3,4,6-tetrakis(benzyloxy)-5-hydroxy-1-(4-methylpiperazin-1-yl) hexan-1-one
829-550-7 1431329-04-2 null Intermediate Joint Intermediate Use Only 13-06-2020 View substance registered dossier
(2R,3S,4R,5R,7R,9R,10R,11S,12S,13R)-10-[(4-dimethylamino-3-hydroxy-6-methyltetrahydropyran-2-yl)oxy]-2-ethyl-3,4,12-trihydroxy-9-methoxy-3,5,7,9,11,13-hexamethyl-6,14-dioxo-1-oxacyclotetradecane
433-820-6 118058-74-5 null NONS Individual Tonnage Data Confidential 02-04-2020 View substance registered dossier
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one
616-385-9 76801-85-9 null Intermediate Individual Intermediate Use Only 24-05-2020 View substance registered dossier
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one
616-385-9 76801-85-9 Active Intermediate Joint Intermediate use only 29-03-2019 View substance registered dossier
(2R,3S,4S)-2,3,4-tris(benzyloxy)-4-{(4R)-4-[(benzyloxy)methyl]-2,2-dimethyl-1,3-dioxolan-4-yl}-1-(4-methylpiperazin-1-yl)butan-1-one
809-911-5 1431329-07-5 null Intermediate Joint Intermediate Use Only 25-05-2020 View substance registered dossier
(2R,5R)-1,6-Diphenylhexane-2,5-diamine dihydrochloride
700-856-1 1247119-31-8 Active Intermediate Joint Intermediate use only 21-02-2017 View substance registered dossier
(2R-(2α,3Z,5α))-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 1:1 salt with 2,4,4-Trimethylpentan-2-amine
613-879-6 66069-32-7 Active Intermediate Individual Intermediate use only 20-05-2013 View substance registered dossier
(2RS, 3SR)-3-(6-chloro-5-fluoro-4-pyrimidinyl)-2-(2,4- difluorphenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol hydrochloride
928-729-8 - null Intermediate Joint Intermediate Use Only 25-03-2020 View substance registered dossier
(2RS,3RS)-3-(2-chlorophenyl)-2-(4-fluorophenyl)-[(1H-1,2,4-triazol-1-yl)methyl]oxirane
406-850-2 133855-98-8 null NONS Individual Tonnage Data Confidential 30-03-2020 View substance registered dossier
(2RS,3SR)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulphonate
917-473-2 - null Intermediate Joint Intermediate Use Only 25-03-2020 View substance registered dossier
(2S)-(5α,7α)-7-(2-hydroxy-3,3-dimethylbutan-2-yl)-3,6-dimethoxy-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-17-carbonitrile
605-429-2 16614-60-1 null Intermediate Individual Intermediate Use Only 24-05-2020 View substance registered dossier
(2S)-(5α,7α)-7-(2-hydroxy-3,3-dimethylbutan-2-yl)-3,6-dimethoxy-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-17-carbonitrile
605-429-2 16614-60-1 null Intermediate Joint Intermediate Use Only 30-04-2020 View substance registered dossier
(2S)-(5α,7α)-7-(2-hydroxy-3,3-dimethylbutan-2-yl)-6-methoxy-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-3-ol
682-862-3 78715-23-8 null Intermediate Individual Intermediate Use Only 24-05-2020 View substance registered dossier
(2S)-(5α,7α)-7-(2-hydroxy-3,3-dimethylbutan-2-yl)-6-methoxy-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-3-ol
682-862-3 78715-23-8 null Intermediate Joint Intermediate Use Only 22-05-2020 View substance registered dossier
(2S)-1,1,2-triphenylethane-1,2-diol
624-788-6 108998-83-0 null Intermediate Joint Intermediate Use Only 22-05-2020 View substance registered dossier
(2S)-1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalene
214-494-2 1135-66-6 null Full Joint 0 - 10 tonnes per annum 01-09-2020 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Clarochem Ireland Ltd damastown mulhuddart dn 15 dublin Ireland - - (2R)-3-chloropropane-1,2-diol 611-463-9 57090-45-6 - View substance registered dossier
Biosint S.p.A. Via Murillo 16 04013 Sermoneta Italy - - (2R)-3-cyano-2-hydroxy-N,N,N-trimethylpropan-1-aminium chloride 700-669-5 2788-28-5 - View substance registered dossier
Barentz Service S.p.A. via Privata Goito, 8 20037 Paderno Dugnano Italy - - (2R)-3-cyano-2-hydroxy-N,N,N-trimethylpropan-1-aminium chloride 700-669-5 2788-28-5 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (2R)-4-hydroxybutan-2-aminium (2S)-hydroxy(phenyl)acetate 810-156-9 1236049-43-6 2016 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (2R)-6-fluoro-2-(oxiran-2-yl)chromane 930-890-4 - 2019 View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France - - (2R)-6-fluorochromane-2-carboxylic acid 810-841-2 129101-37-7 - View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany - - (2R)-acetoxy(phenyl)acetic acid 610-598-0 51019-43-3 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany - - (2R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide - (2R,3R)-2,3-dihydroxysuccinic acid - propan-2-ol (2:1:1) 947-841-8 - - View substance registered dossier
Pfizer Ltd Ramsgate Road (IPC 979) CT13 9NJ Sandwich Kent United Kingdom - - (2R*,3S*)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol (1R)-10-camphorsulfonate 427-100-0 - - View substance registered dossier
Givaudan France SAS - OR1 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France - - (2R*,3S*)-2-acetyl-1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethylnaphthalene; reaction mass of: (1R*,2S*)-2-acetyl-1,2,3,4,5,6,7,8-octahydro-1,2,8,8-tetramethylnaphthalene 425-570-1 - - View substance registered dossier
- - - - (2R*,3S*)-2-acetyl-1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethylnaphthalene; reaction mass of: (1R*,2S*)-2-acetyl-1,2,3,4,5,6,7,8-octahydro-1,2,8,8-tetramethylnaphthalene 425-570-1 - - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (2R,2'R)-3,3'-disulfanediylbis(2-((S)-2-aminopropanamido)propanoic acid) 850-779-3 115888-13-6 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (2R,3R)-2,3-bis(acetyloxy)butanedioic acid - 3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine (1:1) 920-610-9 - - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France - - (2R,3R)-2,3-bis[(4-methoxybenzoyl)oxy]butanedioic acid 672-585-6 50583-51-2 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany - - (2R,3R)-2,3-Dihydroxybutanedioic acid--(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide (1/1) 947-840-2 - - View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy - - (2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol methanesulfonate 815-196-0 1175536-50-1 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy - - (2R,3R)-3-((R)-1-(tert-butyldimethylsiloxy)ethyl)-4-oxoazetidin-2-yl acetate 408-050-9 76855-69-1 - View substance registered dossier
- - - - (2R,3R)-3-((R)-1-(tert-butyldimethylsiloxy)ethyl)-4-oxoazetidin-2-yl acetate 408-050-9 76855-69-1 - View substance registered dossier
L.C.M. TRADING SPA via Mazzini 33 20099 Sesto San Giovanni Lombardia Italy Italy Active (2R,3R)-3-((R)-1-(tert-butyldimethylsiloxy)ethyl)-4-oxoazetidin-2-yl acetate 408-050-9 76855-69-1 - View substance registered dossier
[Confidential] [Confidential] - - (2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 609-299-8 368421-58-3 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (2R,3R)-3-(3-(Benzyloxy)phenyl-2-methylpentanoic acid 805-624-4 1367878-84-9 - View substance registered dossier
DSM Nutritional Products GmbH Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany - - (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate 479-560-7 989-51-5 - View substance registered dossier
- - - - (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate 479-560-7 989-51-5 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy - - (2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol [(1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonic acid 948-743-8 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy - - (2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl L-valinate dihydrochloride 948-534-1 1639208-51-7 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (2R,3R,4R)-3,4-Bis(benzyloxy)-2-((benzyloxy)methyl)-5-methoxytetrahydrofuran 857-987-3 64363-77-5 - View substance registered dossier
Gilead Sciences Ireland UC IDA Business &Technology Park Carrigtohill Cork Cork Ireland - - (2R,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(phenylmethoxy)-5-(phenylmethoxymethyl)oxolane-2-carbonitrile 856-564-0 1355357-49-1 - View substance registered dossier
[Confidential] - - - (2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-(benzoyloxymethyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate 807-677-9 817204-32-3 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy - - (2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-(benzoyloxymethyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate 807-677-9 817204-32-3 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active (2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol 606-239-2 19130-96-2 2011; 2012 View substance registered dossier
Gilead Sciences Ireland UC IDA Business &Technology Park Carrigtohill Cork Cork Ireland - - (2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile 857-885-9 1191237-69-0 - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium - - (2R,3R,4S,5R)-2-(acetoxymethyl)-6-oxotetrahydro-2H-pyran-3,4,5-triyl triacetate 612-107-5 61259-48-1 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium - - (2R,3R,4S,5R)-2-(acetoxymethyl)-6-oxotetrahydro-2H-pyran-3,4,5-triyl triacetate 612-107-5 61259-48-1 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-12,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulfonate 927-721-1 - 2013 View substance registered dossier
Upjohn Manufacturing Ireland Unlimited Little Island T45 F627 Co. Cork Ireland Ireland Active (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-12,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulfonate 927-721-1 - - View substance registered dossier
SCC Scientific Consulting Company GmbH Am Grenzgraben 11 55545 Bad Kreuznach Germany Germany Active (2R,3S)-butane-2,3-diol 823-920-1 5341-95-7 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (2R,3S)-N-(3-amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-nitrobenzenesulfonamide hydrochloride 425-260-6 244634-31-9 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture (2R,3S)-N-(3-amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-nitrobenzenesulfonamide hydrochloride 425-260-6 244634-31-9 2020 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (2R,3S,4R)-2-(Hydroxymethyl)-5-methoxytetrahydrofuran-3,4-diol 857-672-0 13039-63-9 - View substance registered dossier
Euticals SAS ZI de Laville 47240 BON-ENCONTRE France - - (2R,3S,4R,5R)-2,3,4,6-tetrakis(benzyloxy)-5-hydroxy-1-(4-methylpiperazin-1-yl) hexan-1-one 829-550-7 1431329-04-2 - View substance registered dossier
Amri Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy - - (2R,3S,4R,5R)-2,3,4,6-tetrakis(benzyloxy)-5-hydroxy-1-(4-methylpiperazin-1-yl) hexan-1-one 829-550-7 1431329-04-2 - View substance registered dossier
Sanofi Aventis Deutschland GmbH Industriepark Höchst H 831 (Room A0472) z.Hd. Hr. Dr. Schwind 65926 Frankfurt am Main Germany - - (2R,3S,4R,5R,7R,9R,10R,11S,12S,13R)-10-[(4-dimethylamino-3-hydroxy-6-methyltetrahydropyran-2-yl)oxy]-2-ethyl-3,4,12-trihydroxy-9-methoxy-3,5,7,9,11,13-hexamethyl-6,14-dioxo-1-oxacyclotetradecane 433-820-6 118058-74-5 - View substance registered dossier
- - - - (2R,3S,4R,5R,7R,9R,10R,11S,12S,13R)-10-[(4-dimethylamino-3-hydroxy-6-methyltetrahydropyran-2-yl)oxy]-2-ethyl-3,4,12-trihydroxy-9-methoxy-3,5,7,9,11,13-hexamethyl-6,14-dioxo-1-oxacyclotetradecane 433-820-6 118058-74-5 - View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia - - (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one 616-385-9 76801-85-9 - View substance registered dossier
Ercros SA Avenida Diagonal 593-595 08014 Barcelona Spain Spain Active (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one 616-385-9 76801-85-9 - View substance registered dossier
Midas Pharma GmbH Rheinstrasse 49 55218 Ingelheim Germany Germany Active (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one 616-385-9 76801-85-9 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one 616-385-9 76801-85-9 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland - - (2R,3S,4S)-2,3,4-tris(benzyloxy)-4-{(4R)-4-[(benzyloxy)methyl]-2,2-dimethyl-1,3-dioxolan-4-yl}-1-(4-methylpiperazin-1-yl)butan-1-one 809-911-5 1431329-07-5 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active (2R,5R)-1,6-Diphenylhexane-2,5-diamine dihydrochloride 700-856-1 1247119-31-8 2012; 2017 View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active (2R,5R)-1,6-Diphenylhexane-2,5-diamine dihydrochloride 700-856-1 1247119-31-8 2017 View substance registered dossier
SUANFARMA Italia SpA Corso Verona, 165 38068 Rovereto Trentino Alto Adige Italy Italy Active (2R-(2α,3Z,5α))-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 1:1 salt with 2,4,4-Trimethylpentan-2-amine 613-879-6 66069-32-7 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland - - (2RS, 3SR)-3-(6-chloro-5-fluoro-4-pyrimidinyl)-2-(2,4- difluorphenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol hydrochloride 928-729-8 - - View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom - - (2RS,3RS)-3-(2-chlorophenyl)-2-(4-fluorophenyl)-[(1H-1,2,4-triazol-1-yl)methyl]oxirane 406-850-2 133855-98-8 - View substance registered dossier
BASF Schwarzheide GmbH Schipkauer Str. 1 01987 Schwarzheide Brandenburg Germany - - (2RS,3RS)-3-(2-chlorophenyl)-2-(4-fluorophenyl)-[(1H-1,2,4-triazol-1-yl)methyl]oxirane 406-850-2 133855-98-8 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland - - (2RS,3SR)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulphonate 917-473-2 - - View substance registered dossier
Indivior UK Ltd Henry Boot Way HU4 7DY Hull United Kingdom - - (2S)-(5α,7α)-7-(2-hydroxy-3,3-dimethylbutan-2-yl)-3,6-dimethoxy-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-17-carbonitrile 605-429-2 16614-60-1 - View substance registered dossier
Macfarlan Smith Limited Wheatfield Road EH11 2QA Edinburgh United Kingdom - - (2S)-(5α,7α)-7-(2-hydroxy-3,3-dimethylbutan-2-yl)-3,6-dimethoxy-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-17-carbonitrile 605-429-2 16614-60-1 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany - - (2S)-(5α,7α)-7-(2-hydroxy-3,3-dimethylbutan-2-yl)-3,6-dimethoxy-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-17-carbonitrile 605-429-2 16614-60-1 - View substance registered dossier
Indivior UK Ltd Henry Boot Way HU4 7DY Hull United Kingdom - - (2S)-(5α,7α)-7-(2-hydroxy-3,3-dimethylbutan-2-yl)-6-methoxy-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-3-ol 682-862-3 78715-23-8 - View substance registered dossier
Macfarlan Smith Limited Wheatfield Road EH11 2QA Edinburgh United Kingdom - - (2S)-(5α,7α)-7-(2-hydroxy-3,3-dimethylbutan-2-yl)-6-methoxy-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-3-ol 682-862-3 78715-23-8 - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain - - (2S)-1,1,2-triphenylethane-1,2-diol 624-788-6 108998-83-0 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden - - (2S)-1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalene 214-494-2 1135-66-6 - View substance registered dossier
EcoGreen Fine Chemicals B.V. Lichtenauerlaan 102-120 3062ME Rotterdam Netherlands - - (2S)-1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalene 214-494-2 1135-66-6 - View substance registered dossier

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