Registered substances
Registered substances
In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).
ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.
As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).
In the portal results table are presented:
- Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
- Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
- Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
- Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
- Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
- Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
- Link to the full factsheet.
A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.
Please note:
- The REACH Registered substance portal was updated on 9th November 2020; the REACH registered factsheets were further updated on 21st December 2020. Details of the improvements can be found at Dissemination Platform Updates. Reprocessing the entire dataset is ongoing since 21 December 2020. ECHA is making all possible efforts to make the improvements and additional data visible with the shortest delay.
- The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
Further information
- Registered substances information
- How to determine what will be published (Data Submission Manual 15)
- Understanding REACH Regulation
- Q&A on registered substances
- What is an Infocard? [PDF]
- What is a Registered substance Factsheet? [PDF]
- eChemPortal
- REACH study results download
- REACH Regulation
- ECHA Legal notice
Last updated 20 January 2021. Database contains 23121 unique substances and contains information from 101751 dossiers.
| Registrant/Supplier | Address | Country | Registration Status | Name | EC / List no. | CAS no. | Last update year | Details |
|---|---|---|---|---|---|---|---|---|
| F.I.S. Fabbrica Italiana Sintetici S.p.a. | Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy | Italy | Active | (2S)-2-(3-benzoylphenyl)propanoic acid | 606-944-5 | 22161-81-5 | 2019 | View substance registered dossier |
| Lodichem S.r.l. | Via delle Rimembranze, 1 26582 Mairano di Casaletto Lodigiano (Lodi) Italy | Italy | Active | (2S)-2-(3-benzoylphenyl)propanoic acid | 606-944-5 | 22161-81-5 | - | View substance registered dossier |
| LusoChimica S.p.A. | Via Giotto, 9 23871 Lomagna (Lecco) Italy | Italy | Active | (2S)-2-(3-benzoylphenyl)propanoic acid | 606-944-5 | 22161-81-5 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. | - | - | Active | (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid | 431-620-3 | - | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. | - | - | Active | (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid | 431-620-3 | - | - | View substance registered dossier |
| Evonik Operations GmbH | Rellinghauser Straße 1-11 45128 Essen Germany | Germany | Active | (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid | 431-620-3 | - | 2012 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid | 431-620-3 | - | - | View substance registered dossier |
| Evonik Rexim S.A.S. | 33, Rue de Verdun 80400 Ham France | France | Active | (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid | 431-620-3 | - | 2011 | View substance registered dossier |
| Patheon Austria GmbH & Co KG | St. Peterstrasse 25 A-4020 Linz Austria | Austria | Active | (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid | 431-620-3 | - | - | View substance registered dossier |
| Swords Laboratories | Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland | Ireland | Active | (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid | 431-620-3 | - | 2009; 2010; 2017 | View substance registered dossier |
| OLON Spa | Strada Rivoltana Km 6/7 20053 RODANO Milano Italy | - | - | (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid | 431-620-3 | - | - | View substance registered dossier |
| a.c.r.a.f. s.p.a. | via guardapasso 1 04011 aprilia Italy | - | - | (2S)-2-[(4-chlorobenzoyl)oxy]propanoic acid | 817-559-9 | 1047975-16-5 | - | View substance registered dossier |
| Siegfried PharmaChemikalien Minden GmbH | Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany | - | - | (2S)-2-[(5α,7α)-3,6-dimethoxy-17-methyl-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-7-yl]-3,3-dimethylbutan-2-ol | 605-274-0 | 16196-70-6 | - | View substance registered dossier |
| Macfarlan Smith Limited | Wheatfield Road EH11 2QA Edinburgh United Kingdom | - | - | (2S)-2-[(5α,7α)-3,6-dimethoxy-17-methyl-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-7-yl]-3,3-dimethylbutan-2-ol | 605-274-0 | 16196-70-6 | - | View substance registered dossier |
| Alkaloida Chemical Company Zrt. | Kabay Janos 29 H-4440 Tiszavasvari Hungary | - | - | (2S)-2-[(5α,7α)-3,6-dimethoxy-17-methyl-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-7-yl]-3,3-dimethylbutan-2-ol | 605-274-0 | 16196-70-6 | - | View substance registered dossier |
| [Confidential] | [Confidential] | - | - | (2S)-2-[(tert-butoxycarbonyl)amino]butanoic acid | 696-164-1 | 34306-42-8 | - | View substance registered dossier |
| PMC ISOCHEM | 32 rue Lavoisier 91710 VERT LE PETIT France | - | - | (2S)-2-[(tert-butoxycarbonyl)amino]butanoic acid | 696-164-1 | 34306-42-8 | - | View substance registered dossier |
| Medichem S.A. | Polígon Industrial de Celrà 17460 Celrà Girona Spain | - | - | (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid | 406-310-6 | - | - | View substance registered dossier |
| EGIS Pharmaceuticals PLC | Keresztúri út 30-38 H-1106 Budapest Hungary | - | - | (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid | 406-310-6 | - | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. | - | - | Active | (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid | 406-310-6 | - | - | View substance registered dossier |
| Sanofi Aventis Deutschland GmbH | Industriepark Höchst H 831 (Room A0472) z.Hd. Hr. Dr. Schwind 65926 Frankfurt am Main Germany | Germany | Active | (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid | 406-310-6 | - | 2010; 2012 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. | - | - | Active | (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid | 406-310-6 | - | - | View substance registered dossier |
| B.I.G. - OR634 | Technische Schoolstraat 43A 2440 Geel Belgium | Belgium | Active | (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid | 406-310-6 | - | 2011; 2012; 2014; 2020 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid | 406-310-6 | - | - | View substance registered dossier |
| Huvepharma Italia s.r.l. | Via Roberto Lepetit, 142 12075 GARESSIO (CN) Italy | Italy | Active | (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid | 406-310-6 | - | 2010; 2012 | View substance registered dossier |
| Saltigo GmbH | HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany | Germany | Cease Manufacture | (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid | 406-310-6 | - | 2014 | View substance registered dossier |
| MAPIC Europe NV | EXCELSIORLAAN 83 1930 ZAVENTEM Belgium | Belgium | Active | (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid | 406-310-6 | - | - | View substance registered dossier |
| ORIL INDUSTRIE | 13 rue Auguste Desgenétais 76210 BOLBEC France | France | Active | (2S)-2-[[(2S)-1-ethoxy-1-oxopentan-2-yl]amino]propanoic acid | 617-393-5 | 82834-12-6 | 2019; 2020 | View substance registered dossier |
| EGIS Pharmaceuticals PLC | Keresztúri út 30-38 H-1106 Budapest Hungary | - | - | (2S)-2-amino-3-(3,4-dimethoxyphenyl)-2-methylpropanoic acid;hydrochloride | 611-205-5 | 5486-79-3 | - | View substance registered dossier |
| Midas Pharma Polska Sp. z o.o. | Ul. Hankiewicza 2 02-103 Warszawa Poland | - | - | (2S)-2-amino-3-(3,4-dimethoxyphenyl)-2-methylpropanoic acid;hydrochloride | 611-205-5 | 5486-79-3 | - | View substance registered dossier |
| UCB Pharma S.A.(Belgium) | Allée de la recherche, 60 1070 Brussels Belgium | Belgium | Active | (2S)-2-Aminobutyramide Hydrochloride | 471-490-5 | 7682-20-4 | 2013; 2017; 2019; 2020 | View substance registered dossier |
| Sterling Pharma Solutions Ltd | Dudley NE23 7QG Cramlington Northumberland United Kingdom | United Kingdom | Active | (2S)-2-Aminobutyramide Hydrochloride | 471-490-5 | 7682-20-4 | 2020 | View substance registered dossier |
| N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Active | (2S)-2-Aminobutyramide Hydrochloride | 471-490-5 | 7682-20-4 | - | View substance registered dossier |
| OLON Spa | Strada Rivoltana Km 6/7 20053 RODANO Milano Italy | Italy | Active | (2S)-2-{[(1E)-(5-chloro-2-hydroxyphenyl)(phenyl)methylene]amino}-3-methylbutanoic acid | 609-516-6 | 38075-43-3 | 2017; 2018 | View substance registered dossier |
| Avara Shannon Pharmaceutical Services Limited | Shannon Industrial Estate V14 FX09 Shannon Clare Ireland | - | - | (2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride (1:1) | 695-797-0 | 93601-86-6 | - | View substance registered dossier |
| [Confidential] | [Confidential] | - | - | (2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride (1:1) | 695-797-0 | 93601-86-6 | - | View substance registered dossier |
| Avara Shannon Pharmaceutical Services Limited | Shannon Industrial Estate V14 FX09 Shannon Clare Ireland | - | - | (2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-aminium (2R)-(2-chlorophenyl)(hydroxy)acetate | 814-350-4 | 1352917-66-8 | - | View substance registered dossier |
| Janssen Pharmaceutica N.V. | Turnhoutseweg 30 2340 Beerse Belgium | Belgium | Active | (2S)-6-fluoro-2-(oxiran-2-yl)chromane | 930-889-9 | - | 2019 | View substance registered dossier |
| Janssen Pharmaceutica N.V. | Turnhoutseweg 30 2340 Beerse Belgium | Belgium | Active | (2S)-6-fluoro-2-[(2S)-oxiran-2-yl]chromane | 603-314-1 | 129050-23-3 | 2019 | View substance registered dossier |
| F.I.S. Fabbrica Italiana Sintetici S.p.a. | Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy | - | - | (2S)-6-fluoro-2-[(2S)-oxiran-2-yl]chromane | 603-314-1 | 129050-23-3 | - | View substance registered dossier |
| Patheon Austria GmbH & Co KG | St. Peterstrasse 25 A-4020 Linz Austria | Austria | Active | (2S)-[(tert-butoxycarbonyl)amino](3-hydroxytricyclo[3.3.1.1 3,7]dec-1-yl)acetic acid | 700-361-0 | 361442-00-4 | 2010 | View substance registered dossier |
| Piramal Healthcare UK Ltd | Whalton Road NE61 3YA Morpeth Northumberland United Kingdom | United Kingdom | Active | (2S)-[(tert-butoxycarbonyl)amino](3-hydroxytricyclo[3.3.1.1 3,7]dec-1-yl)acetic acid | 700-361-0 | 361442-00-4 | - | View substance registered dossier |
| SK BIOTEK IRELAND LIMITED | Watery Lane Swords K67 AY91 Swords Co. Dublin Ireland | Ireland | Active | (2S)-[(tert-butoxycarbonyl)amino](3-hydroxytricyclo[3.3.1.1 3,7]dec-1-yl)acetic acid | 700-361-0 | 361442-00-4 | 2010; 2014 | View substance registered dossier |
| Arran Chemical Company Ltd | Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland | - | - | (2S)-propane-1,2-diamine dihydrochloride | 606-377-3 | 19777-66-3 | - | View substance registered dossier |
| CU Chemie Uetikon GmbH | Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany | - | - | (2S)-propane-1,2-diamine dihydrochloride | 606-377-3 | 19777-66-3 | - | View substance registered dossier |
| Krka, d. d., Novo mesto | Smarjeska cesta 6 SI-8501 Novo mesto Slovenia | Slovenia | Active | (2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid | 617-180-7 | 80875-98-5 | 2019 | View substance registered dossier |
| ORIL INDUSTRIE | 13 rue Auguste Desgenétais 76210 BOLBEC France | France | Active | (2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid | 617-180-7 | 80875-98-5 | 2019; 2020 | View substance registered dossier |
| Patheon Austria GmbH & Co KG | St. Peter Strasse 25 4021 Linz Austria | - | - | (2S,3R,4R,5R)-2,4-bis(acetyloxy)-5-methyloxolan-3-yl acetate | 612-957-7 | 62211-93-2 | - | View substance registered dossier |
| F.I.S. Fabbrica Italiana Sintetici S.p.a. | Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy | - | - | (2S,3R,4R,5R)-2,4-bis(acetyloxy)-5-methyloxolan-3-yl acetate | 612-957-7 | 62211-93-2 | - | View substance registered dossier |
| Roche Ireland Limited | Clarehill . Clarecastle Ireland | - | - | (2S,3R,4R,5R)-2,4-bis(acetyloxy)-5-methyloxolan-3-yl acetate | 612-957-7 | 62211-93-2 | - | View substance registered dossier |
| CHEMICAL INSPECTION & REGULATION SERVICE LIMITED | Regus Harcourt Centre D02 HW77 Dublin Ireland | Ireland | Active | (2S,3R,4S,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-ol | 667-304-9 | 6564-72-3 | 2019 | View substance registered dossier |
| REACH24H CONSULTING GROUP | Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland | Ireland | Active | (2S,3R,4S,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-ol | 667-304-9 | 6564-72-3 | 2020 | View substance registered dossier |
| MSD International GmbH | Ballydine - Kilsheelan 0 Clonmel Ireland | - | - | (2S,3S)-2,3-Bis[(4-methylbenzoyl)oxy]butanedioic acid — methyl {(4S)-8-fluoro-2-[4-(3methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4yl}acetate — ethyl acetate (1:1:1) | 947-432-4 | - | - | View substance registered dossier |
| Boehringer Ingelheim Pharma GmbH & Co. KG | Binger Strasse 173 55216 Ingelheim am Rhein Germany | Germany | Active | (2S,3S)-2,3-dihydroxybutanedioic acid;2-[(3R)-piperidin-3-yl]isoindole-1,3-dione | 692-713-4 | 886588-62-1 | 2016; 2019 | View substance registered dossier |
| AGC Pharma Chemicals Europe, S.L.U. | Camí de la Pomereda, 13 08380 Malgrat de Mar (Barcelona) Spain | Spain | Active | (2S,3S)-2,3-dihydroxybutanedioic acid;2-[(3R)-piperidin-3-yl]isoindole-1,3-dione | 692-713-4 | 886588-62-1 | - | View substance registered dossier |
| Bidachem S.p.A. | S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy | Italy | Active | (2S,3S)-2,3-dihydroxybutanedioic acid;2-[(3R)-piperidin-3-yl]isoindole-1,3-dione | 692-713-4 | 886588-62-1 | 2019 | View substance registered dossier |
| Zoetis Belgium S.A. | Rue Laid Burniat, 1 1348 Louvain-La-Neuve Belgium | Belgium | Active | (2S,3S)-2-benzhydryl-N-[(5-tert-butyl-2-methoxy-phenyl)methyl]quinuclidin-3-amine | 831-973-7 | 147116-67-4 | - | View substance registered dossier |
| Janssen Pharmaceutica N.V. | Turnhoutseweg 30 2340 Beerse Belgium | Belgium | Active | (2S,3S)-3-(ethoxycarbonyl)bicyclo[2.2.2]octan-2-aminium chloride | 812-619-0 | 1626394-43-1 | - | View substance registered dossier |
| Envigo Consulting Limited | Woolley Road Alconbury PE28 4HS Huntingdon Cambridgeshire United Kingdom | United Kingdom | Cease Manufacture | (2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride | 478-270-8 | - | 2019 | View substance registered dossier |
| [Confidential] | - | - | - | (2S,3S,4R)-2-aminooctadecane-1,3,4-triol | 439-210-6 | 554-62-1 | - | View substance registered dossier |
| KIST Europe | Campus E7.1 66123 Saarbrücken Germany | Germany | Active | (2S,3S,4R)-2-aminooctadecane-1,3,4-triol | 439-210-6 | 554-62-1 | - | View substance registered dossier |
| Gilead Sciences Ireland UC | IDA Business &Technology Park Carrigtohill Cork Cork Ireland | Ireland | Active | (2S,3S,4R)-3-ethyl-4-hydroxy-2-(methoxycarbonyl)pyrrolidinium 4-methylbenzenesulfonate | 813-641-3 | 1799733-43-9 | - | View substance registered dossier |
| Gilead Sciences Ireland UC | IDA Business &Technology Park Carrigtohill Cork Cork Ireland | Ireland | Active | (2S,3S,4R)-4-{[3-(1,1-difluorobut-3-en-1-yl)-7-methoxyquinoxalin-2-yl]oxy}-3-ethyl-2-(methoxycarbonyl)pyrrolidinium 4-methylbenzenesulfonate | 942-021-6 | 1799733-71-3 | - | View substance registered dossier |
| Esteve Quimica, S.A. | Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain | Spain | Active | (2S,3S,4R)-4-{[3-(1,1-difluorobut-3-en-1-yl)-7-methoxyquinoxalin-2-yl]oxy}-3-ethyl-2-(methoxycarbonyl)pyrrolidinium 4-methylbenzenesulfonate | 942-021-6 | 1799733-71-3 | - | View substance registered dossier |
| OLON Spa | Strada Rivoltana Km 6/7 20053 RODANO Milano Italy | Italy | Active | (2S,3S,4R)-4-{[3-(1,1-difluorobut-3-en-1-yl)-7-methoxyquinoxalin-2-yl]oxy}-3-ethyl-2-(methoxycarbonyl)pyrrolidinium 4-methylbenzenesulfonate | 942-021-6 | 1799733-71-3 | - | View substance registered dossier |
| Patheon Austria GmbH & Co KG | St. Peter Strasse 25 4021 Linz Austria | - | - | (2S,3S,5R)-2-hexyl-3-hydroxy-5-(phenylmethoxy)-Hexadecanoic acid compd. with (S)-α-methylbenzenemethanamine (1:1) | 604-018-5 | 137433-01-3 | - | View substance registered dossier |
| FIS Fabbrica Italiana Sintetici SpA | Viale Milano, 26 36075 Montecchio Maggiore (Vicenza) Italy | - | - | (2S,3S,5R)-2-hexyl-3-hydroxy-5-(phenylmethoxy)-Hexadecanoic acid compd. with (S)-α-methylbenzenemethanamine (1:1) | 604-018-5 | 137433-01-3 | - | View substance registered dossier |
| FRESENIUS KABI iPSUM s.r.l. | Via Roma, 108 20060 Cassina de' Pecchi (MI) Italy | - | - | (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide | 618-303-7 | 89786-04-9 | - | View substance registered dossier |
| IBI - Istituto Biochimico Italiano Giovanni Lorenzini Spa | Via Fossignano, 2 04011 Aprilia (LT) Italy | - | - | (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide | 618-303-7 | 89786-04-9 | - | View substance registered dossier |
| Sandoz Industrial Products SA | Ctra. Granollers - Cardedeu C-251, Km 4 08520 Les Franqueses del Vallés Spain | - | - | (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide | 618-303-7 | 89786-04-9 | - | View substance registered dossier |
| AbbVie Srl | S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy | - | - | (2S,3S,5S)-5-amino-2-(dibenzylamino)-1,6-diphenylhexan-3-ol succinate | 938-481-2 | - | - | View substance registered dossier |
| Symrise AG | Mühlenfeldstraße 1 37603 Holzminden Germany | - | - | (2S,4aR)-1,1,5,5-tetramethyl-1,3,4,5,6,7-hexahydro-2H-2,4a-methanonaphthalen-7-ol | 942-036-8 | 645413-57-6 | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. | - | - | Active | (2S,4R)-1-benzoyl-4-hydroxy-pyrrolydin-2-carboxylic acid methyl ester | 411-020-8 | - | - | View substance registered dossier |
| Corden Pharma Latina S.p.A. | Via del Murillo Km 2, 800 IT04013 Sermoneta (LT) Lazio Italy | Italy | Cease Manufacture | (2S,4R)-1-benzoyl-4-hydroxy-pyrrolydin-2-carboxylic acid methyl ester | 411-020-8 | - | 2017 | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | (2S,4R)-1-benzoyl-4-hydroxy-pyrrolydin-2-carboxylic acid methyl ester | 411-020-8 | - | - | View substance registered dossier |
| Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. | - | - | Active | (2S,4R)-1-benzoyl-4-hydroxy-pyrrolydin-2-carboxylic acid methyl ester | 411-020-8 | - | - | View substance registered dossier |
| Symrise AG | Mühlenfeldstraße 1 37603 Holzminden Germany | - | - | (2S,4R)-1-hexadecanoyl-4-hydroxy-pyrrolidine-2-carboxylic acid | 944-347-4 | - | - | View substance registered dossier |
| AbbVie Srl | S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy | - | - | (2S,4Z)-5-amino-2-(dibenzylamino)-1,6-diphenylhex-4-en-3-one; 5-amino-[2S-di(methylphenyl)amino]-1,6-diphenyl-4Z-hexen-3-one | 423-090-7 | 156732-13-7 | - | View substance registered dossier |
| ITELYUM Purification S.r.l. | Via S. Intini n. 2 27015 Landriano (PV) Italy | - | - | (2S,4Z)-5-amino-2-(dibenzylamino)-1,6-diphenylhex-4-en-3-one; 5-amino-[2S-di(methylphenyl)amino]-1,6-diphenyl-4Z-hexen-3-one | 423-090-7 | 156732-13-7 | - | View substance registered dossier |
| Zoetis Belgium S.A. | Rue Laid Burniat, 1 1348 Louvain-La-Neuve Belgium | Belgium | Active | (2S-cis)-(diphenylmethyl)-N-(phenylmethyl)-1-azabicyclo[2.2.2.]octan-3-amine (1-R camphor-10-sulfonate) | 444-810-6 | - | - | View substance registered dossier |
| F.I.S. Fabbrica Italiana Sintetici S.p.a. | Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy | - | - | (2S-cis)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one | 255-799-0 | 42399-49-5 | - | View substance registered dossier |
| LusoChimica S.p.A. | Via Giotto, 9 23871 Lomagna (Lecco) Italy | - | - | (2S-cis)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one | 255-799-0 | 42399-49-5 | - | View substance registered dossier |
| Cambrex Profarmaco Milano Srl | via Curiel, 34 20067 Paullo MI Italy | - | - | (2S-cis)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one | 255-799-0 | 42399-49-5 | - | View substance registered dossier |
| Fermion Oy | Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland | - | - | (2S-cis)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one | 255-799-0 | 42399-49-5 | - | View substance registered dossier |
| FINORGA - MOURENX | avenue du lac 64150 MOURENX France | France | Active | (2S-cis)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one | 255-795-9 | 42399-40-6 | - | View substance registered dossier |
| Corden Pharma Latina S.p.A. | Via del Murillo Km 2, 800 IT04013 Sermoneta (LT) Lazio Italy | - | - | (2S-trans)-3-amino-2-methyl-4-oxoazetidine-1-sulphonic acid | 279-393-8 | 80082-65-1 | - | View substance registered dossier |
| Amri Italy S.r.l. | VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy | - | - | (2S-trans)-3-amino-2-methyl-4-oxoazetidine-1-sulphonic acid | 279-393-8 | 80082-65-1 | - | View substance registered dossier |
| AZOINTERNATIONAL OU | RAUA 28 10152 TALLINN Estonia | - | - | (2Z)-(5-amino-1,2,4-thiadiazol-3-yl)(ethoxyimino)acetic acid | 616-178-3 | 75028-24-9 | - | View substance registered dossier |
| Corden Pharma Latina S.p.A. | Via del Murillo Km 2, 800 IT04013 Sermoneta (LT) Lazio Italy | - | - | (2Z)-(5-amino-1,2,4-thiadiazol-3-yl){[(1-tert-butoxy-2-methyl-1-oxopropan-2-yl)oxy]imino}acetic acid | 616-285-5 | 76028-96-1 | - | View substance registered dossier |
| Chemours Netherlands B.V. | Baanhoekweg 22 3313 LA Dordrecht Netherlands | Netherlands | Active | (2Z)-1,1,1,4,4,4-Hexafluorobut-2-ene | 700-651-7 | 692-49-9 | 2014; 2015; 2019 | View substance registered dossier |
| Chemours Netherlands B.V._1 | Baanhoekweg 22 3313 LA Dordrecht Netherlands | Netherlands | Active | (2Z)-1,1,1,4,4,4-Hexafluorobut-2-ene | 700-651-7 | 692-49-9 | - | View substance registered dossier |
| MINAKEM Beuvry Production SAS | 145, Chemin des Lilas 59310 Beuvry-la-Forêt France | France | Active | (2Z)-2-fluoro-3-(morpholin-4-yl)acrylaldehyde | 813-789-9 | 152873-67-1 | - | View substance registered dossier |
| Bayer AG | Kaiser-Wilhelm-Allee 51373 Leverkusen Germany | Germany | Active | (2Z)-2-fluoro-3-(morpholin-4-yl)acrylaldehyde | 813-789-9 | 152873-67-1 | 2020 | View substance registered dossier |
| PMC ISOCHEM | 32 rue Lavoisier 91710 VERT LE PETIT France | France | Active | (2Z)-2-fluoro-3-(morpholin-4-yl)acrylaldehyde | 813-789-9 | 152873-67-1 | - | View substance registered dossier |
| FIRMENICH GRASSE SAS OR 1 | Parc Industriel Les Bois de Grasse 06130 Grasse France | France | Active | (2Z)-2-phenylhex-2-enenitrile | 482-160-5 | 130786-09-3 | 2020 | View substance registered dossier |
| FIRMENICH GRASSE SAS OR 2 | Parc Industriel Les Bois de Grasse 06130 Grasse France | France | Active | (2Z)-2-phenylhex-2-enenitrile | 482-160-5 | 130786-09-3 | 2020 | View substance registered dossier |
| FIRMENICH GRASSE SAS OR 1 | Parc Industriel Les Bois de Grasse 06130 Grasse France | - | - | (2Z)-4,8-dimethylnona-2,7-dien-4-ol | 807-754-7 | 89929-57-7 | - | View substance registered dossier |
| ACS DOBFAR S.p.A | Viale Addetta 4/12 20067 Tribiano Milano Italy | - | - | (2Z)-7-chloro-2-({[(1S)-2,2-dimethylcyclopropyl]carbonyl}amino)hept-2-enoic acid | 618-065-4 | 877674-77-6 | - | View substance registered dossier |
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