Registered substances

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.


 

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
(R)-1-cyclohexa-1,4-dienyl-1-methoxycarbonyl-methylammoniumchloride
444-320-2 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol
929-946-0 - Active Intermediate Joint Intermediate use only 05-12-2017 View substance registered dossier
(R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol (R)-acetoxy(phenyl)acetate
929-947-6 - Active Intermediate Joint Intermediate use only 31-10-2017 View substance registered dossier
(R)-2-acetamido-3-naphthyl-2-yl-propionic acid
(R)-2-ACETAMIDO-3-NAPHTHYLEN-2-YL-PROPIONIC ACID
440-450-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-2-dimethylamino-4-imino-6-methyl-1,4,5,6-tetrahydro-1,3,5-triazine, L-tartrate
942-402-7 - Active Intermediate Joint Intermediate use only 24-09-2021 View substance registered dossier
(R)-2-tert-butoxycarbonylamino-3-(4-chlorophenyl)propionic acid
(R)-2-TERT-BUTOXYCARBONYLAMINO-3-(4-CHLOROPHENYL)-PROPIONIC ACID
438-070-3 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-2-tert-butoxycarbonylamino-3-(pyridin-3-yl)propionic acid
(R)-2-TERT-BUTOXYCARBONYLAMINO-3-(PYRIDIN-3-YL) PROPIONIC ACID
441-200-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-3-(1-methyl-2-pyrrolidinylmethyl)-5-[2-(phenylsulphonyl)ethyl]-1H-indole
921-685-0 - Active Intermediate Joint Intermediate use only 05-08-2022 View substance registered dossier
(R)-4-(4-dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemi (2R, 3R)-2,3-bis((4-methylbenzoyl)oxy)succinoate
949-784-4 - Active Intermediate Individual Intermediate use only 25-03-2019 View substance registered dossier
(R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide (7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate
920-209-9 - Active Intermediate Joint Intermediate use only 30-05-2018 View substance registered dossier
(R)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide
419-800-1 - Active Full Joint ≥ 0 to < 10 tonnes 05-12-2019 View substance registered dossier
(R)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide
419-800-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)-benzonitrile hemisulfate
430-790-6 - Active Intermediate Joint Intermediate use only 05-05-2015 View substance registered dossier
(R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)-benzonitrile hemisulfate
430-790-6 - Active Intermediate Joint Intermediate use only 01-05-2018 View substance registered dossier
(Reaction product of 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol, 2-(2-hydroxyethylamino)ethanol and formaldehyde), propoxylated
926-000-9 - Active Full Individual ≥ 100 to < 1 000 tonnes 11-07-2022 View substance registered dossier
(RS)-3-dichloroacetyl-5-(2-furanyl)-2,2-dimethyloxazolidine
434-800-1 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(RS)-3-dichloroacetyl-5-(2-furanyl)-2,2-dimethyloxazolidine
434-800-1 - Cease Manufacture Full Individual Cease manufacture 05-11-2020 View substance registered dossier
(S) (2Z,4E)-4-carboxy-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoic acid disodium salt
918-890-2 - Active Intermediate Joint Intermediate use only 23-03-2018 View substance registered dossier
(S)-(-)-tetrahydro-2-furoic acid
433-770-5 - No longer Valid Intermediate Individual No longer valid 22-09-2011 View substance registered dossier
(S)-(-)-tetrahydro-2-furoic acid
433-770-5 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(S)-1,2,4-butanetriyltrimethanesulfonate
UK-164,608
433-850-1 - Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
(S)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole Tartrat Trihydrate
928-472-1 - Active Intermediate Joint Intermediate use only 26-10-2021 View substance registered dossier
(S)-2-(1-aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one hydrochloride
942-180-1 - Cease Manufacture Intermediate Individual Cease manufacture 28-08-2015 View substance registered dossier
(S)-2-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid
951-381-3 - Active Intermediate Individual Intermediate use only 02-07-2021 View substance registered dossier
(S)-2-(5-Methylheteromonocycle-2-carboxamido)-alkenoic acid
- - Active Intermediate Joint Intermediate use only 09-10-2013 View substance registered dossier
(S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid
FMOC AMINO ACID 4
439-640-4 - Active Intermediate Individual Intermediate use only 07-02-2022 View substance registered dossier
(S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid
FMOC AMINO ACID 4
439-640-4 - Active NONS Joint Tonnage data confidential 17-08-2010 View substance registered dossier
(S)-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid
ECTOIN
431-910-1 - Active Full Joint ≥ 1 tonnes 19-08-2022 View substance registered dossier
(S)-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid
ECTOIN
431-910-1 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
(S)-3-[1-(Dimethylamino)ethyl]-phenol
478-670-2 - Active Intermediate Joint Intermediate use only 11-10-2010 View substance registered dossier
(S)-3-[5-(4-Fluorophenyl)-1,5-dioxopentyl]-4-phenyloxazolidin-2-one
480-320-9 - Active Full Joint ≥ 0 tonnes 06-02-2009 View substance registered dossier
(S)-3-[5-(4-Fluorophenyl)-1,5-dioxopentyl]-4-phenyloxazolidin-2-one
480-320-9 - Active Intermediate Joint Intermediate use only 10-07-2019 View substance registered dossier
(S)-3-Hydroxytetrahydrofurane
425-090-2 - Cease Manufacture Intermediate Joint Cease manufacture 10-05-2010 View substance registered dossier
(S)-3-Hydroxytetrahydrofurane
425-090-2 - No longer Valid NONS Joint No longer valid 10-11-2008 View substance registered dossier
(S)-3-Hydroxytetrahydrofurane
425-090-2 - Active Intermediate Joint Intermediate use only 14-02-2020 View substance registered dossier
(S)-4-amino-5-[(2-(1H-imidazol-4-yl)ethyl)amino]-5-oxopentanoic acid
L-GLUTAMYL-HISTAMINE
421-900-3 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
(S)-5-[2-(acetyloxy)propanamido]-2,4,6-triiodo-1,3-di(chloroformyl)benzene
LACTOFTALURO
410-940-7 - Active Intermediate Joint Intermediate use only 20-05-2022 View substance registered dossier
(S)-5-chloro-4-methyl-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole dihydrochloride
948-271-2 - Active Intermediate Joint Intermediate use only 09-07-2018 View substance registered dossier
(S)-6-(2-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-2-oxoethyl) 5-tert-butyl 5-azaspiro[2.4]heptane-5,6-dicarboxylate
941-125-9 - Cease Manufacture Intermediate Joint Cease manufacture 09-06-2015 View substance registered dossier
(S)-7-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one glucopyranosyl ether
471-940-0 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle
439-220-0 - Active Intermediate Joint Intermediate use only 08-07-2015 View substance registered dossier
(S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle
439-220-0 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate
445-820-3 - Active Intermediate Individual Intermediate use only 19-06-2018 View substance registered dossier
(S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate
445-820-3 - Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
(S)-ethyl-3-amino-3-phenylpropanoate hemi (2S,3S)-2,3-dihydroxysuccinate
955-403-2 - Active Intermediate Joint Intermediate use only 14-10-2022 View substance registered dossier
(S)-N-[[3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-amine
942-077-1 - Active Intermediate Joint Intermediate use only 18-01-2018 View substance registered dossier
(S)-propane-1,2-diamine bis((2S,3S)-2,3-dihydroxysuccinate) dihydrate
924-425-4 - Active Intermediate Joint Intermediate use only 07-08-2020 View substance registered dossier
(S)-tert-butyl(1-((3-fluoro-2-(phenylcarbamoyl)phenyl)amino)-1-oxobutan-2 yl)carbamate
942-159-7 - Cease Manufacture Intermediate Individual Cease manufacture 20-07-2015 View substance registered dossier
(S)-tert.-Butyl-[2-(aminoethoxy)-[1,2]oxaborolan-4-yl]acetate
942-682-0 - Active Intermediate Individual Intermediate use only 05-03-2018 View substance registered dossier
(S)Ammonium-(2E,4E)-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate
926-381-1 - Active Intermediate Joint Intermediate use only 23-03-2018 View substance registered dossier
(trans(trans))-4'-but-3-enyl-4-(4-methylphenyl)-bicyclohexyl
1-(TRANS,TRANS-4'-(3-BUTENYL)-BICYCLOHEXYL-4-YL)-4-METHYLBEN
429-580-7 - Active Full Joint ≥ 0 to < 10 tonnes 06-02-2020 View substance registered dossier
(trans(trans))-4'-vinyl-4-(4-methylphenyl)bicyclohexyl
LICRISTAL CCP-V-1
439-730-3 - Active Full Joint ≥ 0 to < 10 tonnes 02-12-2019 View substance registered dossier
(Trimethoxysilyl)methyl 2-methacrylate
454-220-0 - Active Full Joint ≥ 10 tonnes 16-11-2016 View substance registered dossier
(TRIMETHYLENEDINITRILO)TETRAKISACETONITRILE
429-330-7 - Cease Manufacture Intermediate Individual Cease manufacture 03-02-2012 View substance registered dossier
(trimethylvinylsilyl)hexafluoroacetylacetonato copper I
CUPRA SELECT
435-140-5 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(xylenes and 4-ethylbenzene)sulfonic acids
701-247-3 - Active Full Joint ≥ 1 000 to < 10 000 tonnes 06-03-2023 View substance registered dossier
(Z)-3-(chloro((2-hydroxy-3-(piperidin-1-yl)propoxy)imino)methyl)pyridine 1-oxide
953-723-7 - Active Intermediate Joint Intermediate use only 22-02-2021 View substance registered dossier
(Z)-4-[C11-13 (branched) alkylamino]-4-oxo-2-butenoic acid
701-116-0 - Active Full Joint ≥ 10 to < 100 tonnes 29-07-2022 View substance registered dossier
(Z)-5-Amino-α-(methoxyimino)-1,2,4-thiadiazole-3-acetic acid
456-150-6 - Cease Manufacture NONS Individual Cease manufacture 04-03-2011 View substance registered dossier
(Z)-but-2-enedioic acid;N-[2-(dimethylamino)ethyl]-5-(dithiolan-3-yl)pentanamide
922-363-2 - Active Full Individual ≥ 0 to < 10 tonnes 26-09-2019 View substance registered dossier
(Z)-N-(3-ammoniopropyl)-N'-[3-octadecenylamino)propyl]propane-1,3-diaminium acetate
700-802-7 - Active Full Joint ≥ 10 to < 100 tonnes 30-09-2013 View substance registered dossier
(Z)-N-(3-ammoniopropyl)-N'-octadecenylpropane-1,3-diaminium acetate
700-764-1 - Active Full Joint ≥ 10 to < 100 tonnes 30-09-2013 View substance registered dossier
({4-(3-Chloro-4-fluoro-phenylamino)-7-[(S)-(tetrahydro-furan-3-yl)oxy]-quinazolin-6-ylcarbamoyl}-methyl)-phosphonic acid diethyl ester
928-634-1 - Active Intermediate Joint Intermediate use only 05-04-2021 View substance registered dossier
1,1'-(2,3-dimethylbutane-2,3-diyl)bis[4-(propan-2-yl)benzene]
449-400-0 - Active Full Joint ≥ 10 to < 100 tonnes 11-05-2016 View substance registered dossier
1,1'-(dodecylimino)dipropan-2-ol + 1,1'-(tetradecylimino)dipropan-2-ol
911-174-0 - Active Intermediate Joint Intermediate use only 30-01-2013 View substance registered dossier
1,1'-(methylenedi-4,1-phenylene)bis(3-butylurea)
416-600-4 - No longer Valid NONS Joint No longer valid 10-11-2008 View substance registered dossier
1,1'-(methylenedi-4,1-phenylene)bis(3-butylurea)
416-600-4 - Active Full Joint ≥ 1 000 tonnes 25-08-2021 View substance registered dossier
1,1'-[propane-1,3-diylbis(oxy)]bis(2-bromo-4-tert-butylbenzene)
925-064-5 - Active Intermediate Individual Intermediate use only 23-04-2019 View substance registered dossier
1,1'-[propane-1,3-diylbis(oxy)]bis(2-bromo-4-tert-butylbenzene)
925-064-5 - Active Intermediate Joint Intermediate use only 24-10-2022 View substance registered dossier
1,1'-Biphenyl, 4'-butyl-3-fluoro-
935-978-6 - Active Intermediate Joint Intermediate use only 13-12-2017 View substance registered dossier
1,1'-bis(diphenylphosphino) ferrocene
1,1'-BIS(DIPHENYLPHOSPHINO) FERROCENE
430-420-3 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
1,1'-Methylenebis(4-isocyanatobenzene) and 1,1'-methylenebis(4-isocyanatobenzene) homopolymer and their reaction products with [(methylethylene)bis(oxy)]dipropanol and butane-1,3-diol and propane-1,2-diol
701-393-8 - Active Full Joint ≥ 100 000 to < 1 000 000 tonnes 27-10-2021 View substance registered dossier
1,1'-Methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with [(methylethylene)bis(oxy)]dipropanol
701-124-4 - Active Full Joint ≥ 10 000 to < 100 000 tonnes 18-08-2022 View substance registered dossier
1,1'-methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with butane-1,3-diol, 2,2'-oxydiethanol and propane-1,2-diol
701-173-1 - Active Full Joint ≥ 100 000 to < 1 000 000 tonnes 22-10-2021 View substance registered dossier
1,1'-Methylenebis(4-isocyanatobenzene) and oligomeric reaction products of 1,1'-methylenebis(4-isocyanatobenzene) and oxydipropanol
701-040-8 - Active Full Joint ≥ 100 000 to < 1 000 000 tonnes 10-12-2021 View substance registered dossier
1,1'-Methylenebis(4-isocyanatobenzene) and oligomeric reaction products of 1,1'-methylenebis(4-isocyanatobenzene) and oxydipropanol and oligomerization reaction products of oxydipropanol
701-041-3 - Active Full Joint ≥ 10 000 to < 100 000 tonnes 21-10-2021 View substance registered dossier
1,1'-{2-(2,4-difluorophenyl)-2-[(trimethylsilyl)oxy]propane-1,3-diyl}bis(1H-1,2,4-triazole)
928-141-1 - Active Intermediate Joint Intermediate use only 10-12-2021 View substance registered dossier
1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluorotetradecane
432-570-5 - Active Full Joint ≥ 10 to < 100 tonnes 11-06-2019 View substance registered dossier
1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluorotetradecane
432-570-5 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
1,1,1,2,3,3-hexafluoro-4-(1,1,2,3,3,3-hexafluoropropoxy)pentane
484-290-8 - Active NONS Individual Tonnage data confidential 15-03-2011 View substance registered dossier
1,1,1-Tri((1,3-dioxobutoxy)-methyl)-propane
422-630-9 - Active Full Joint ≥ 1 to < 10 tonnes 27-04-2023 View substance registered dossier
1,1,1-Tri((1,3-dioxobutoxy)-methyl)-propane
422-630-9 - Active NONS Joint Tonnage data confidential 09-12-2010 View substance registered dossier
1,1,1-trimethyl-2-(methoxycarbonylethyl)hydrazonium bromide
463-070-5 - Active Intermediate Individual Intermediate use only 13-03-2020 View substance registered dossier
1,1,1-Tris(p-hydroxyphenyl)ethane, mixed esters with 3-Diazo-3,4-dihydro-4-oxonaphthalene 2-sulphonic acid and 6-Diazo-5,6-dihydro-5-oxonaphthalene 2-sulphonic acid
422-760-6 - Cease Manufacture NONS Individual Cease manufacture 07-02-2011 View substance registered dossier
1,1,2,2,3,3,4,4,4-nonafluoro-N,N-bis(2-hydroxyethyl)-1-butanesulfonamide
454-680-2 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
1,1,2,2,3,3-hexafluoro-1-trifluoromethoxy-3-trifluorovinyloxypropane
442-390-9 - Active Full Joint ≥ 10 to < 100 tonnes 04-10-2018 View substance registered dossier
1,1,2,2-tetramethoxyethane
463-280-7 - Cease Manufacture NONS Individual Cease manufacture 01-03-2018 View substance registered dossier
1,1,3,3-Tetraoctyl-1-3-bis((2,2,3,5-oxotetramethylhexyl)oxy)distannoxane, dimer
947-528-6 - Active Full Individual ≥ 100 to < 1 000 tonnes 18-12-2019 View substance registered dossier
1,1-bis(4-hydroxy-2,5-dimethylphenyl)acetone
433-650-2 - Active NONS Individual Tonnage data confidential 14-01-2013 View substance registered dossier
1,1-cyclohexanediacetic acid monoamide
1,1-CYCLOHEXANE DIACETIC ACID MONOAMIDE (CAM); 1,1-CYCLOHEXANEDIACETIC ACID MONOAMIDE
449-430-4 - Active Intermediate Individual Intermediate use only 25-02-2010 View substance registered dossier
1,1-cyclohexanediacetic acid monoamide
1,1-CYCLOHEXANE DIACETIC ACID MONOAMIDE (CAM); 1,1-CYCLOHEXANEDIACETIC ACID MONOAMIDE
449-430-4 - Active Intermediate Individual Intermediate use only 15-10-2010 View substance registered dossier
1,1-cyclohexanediacetic acid monoamide
1,1-CYCLOHEXANE DIACETIC ACID MONOAMIDE (CAM); 1,1-CYCLOHEXANEDIACETIC ACID MONOAMIDE
449-430-4 - Active Intermediate Individual Intermediate use only 26-02-2010 View substance registered dossier
1,1-cyclohexanediacetic acid monoamide
1,1-CYCLOHEXANE DIACETIC ACID MONOAMIDE (CAM); 1,1-CYCLOHEXANEDIACETIC ACID MONOAMIDE
449-430-4 - Active Intermediate Joint Intermediate use only 11-03-2011 View substance registered dossier
1,12-bis (diisopropyl phosphoryl) dodecane
919-645-2 - Cease Manufacture Intermediate Joint Cease manufacture 07-10-2015 View substance registered dossier
1,12-DODECYLDIPHOSPHONIC ACID
435-710-3 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
1,18-octadecanedioic acid
EMEROX 118
442-490-2 - Active Full Joint ≥ 100 to < 1 000 tonnes 02-02-2023 View substance registered dossier
1,18-octadecanedioic acid
EMEROX 118
442-490-2 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
1,1’-Methylenebis(4-isocyanatobenzene) and its reaction products with [(methylethylene)bis(oxy)]dipropanol, butane-1,3-diol and propylene glycol
941-496-7 - Active Full Joint ≥ 100 000 to < 1 000 000 tonnes 22-10-2021 View substance registered dossier
1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-2-naphtalensulfonate of 1,3,5-triazine-2,4,6-triamer
MENADIONE TRIAMINOTRIAZINE BISULPHITE
433-290-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
1,2,3,6,7,11b-HEXAHYDRO-PYRAZINO[2,1-a]ISOQUINOLIN-4-ONE
917-666-1 - Active Intermediate Joint Intermediate use only 19-06-2017 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (R)-1-cyclohexa-1,4-dienyl-1-methoxycarbonyl-methylammoniumchloride 444-320-2 - - View substance registered dossier
Deretil S.A.U. Villaricos, s/n 04618 Cuevas del Almanzora Almeria Spain Spain Cease Manufacture (R)-1-cyclohexa-1,4-dienyl-1-methoxycarbonyl-methylammoniumchloride 444-320-2 - 2019 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol 929-946-0 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol (R)-acetoxy(phenyl)acetate 929-947-6 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-2-acetamido-3-naphthyl-2-yl-propionic acid 440-450-9 - - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (R)-2-dimethylamino-4-imino-6-methyl-1,4,5,6-tetrahydro-1,3,5-triazine, L-tartrate 942-402-7 - 2018; 2021 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France No longer Valid (R)-2-dimethylamino-4-imino-6-methyl-1,4,5,6-tetrahydro-1,3,5-triazine, L-tartrate 942-402-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-2-tert-butoxycarbonylamino-3-(4-chlorophenyl)propionic acid 438-070-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-2-tert-butoxycarbonylamino-3-(pyridin-3-yl)propionic acid 441-200-1 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (R)-3-(1-methyl-2-pyrrolidinylmethyl)-5-[2-(phenylsulphonyl)ethyl]-1H-indole 921-685-0 - - View substance registered dossier
Upjohn Manufacturing Ireland Unlimited Little Island T45 F627 Co. Cork Ireland Ireland Active (R)-3-(1-methyl-2-pyrrolidinylmethyl)-5-[2-(phenylsulphonyl)ethyl]-1H-indole 921-685-0 - - View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active (R)-4-(4-dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemi (2R, 3R)-2,3-bis((4-methylbenzoyl)oxy)succinoate 949-784-4 - - View substance registered dossier
Synthon, s.r.o. Brněnská 32 678 01 Blansko Czech Republic Czech Republic Active (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide (7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate 920-209-9 - - View substance registered dossier
Astellas Ireland Co.Ltd Damastown Road Damastown Industrial Park NA Mulhuddart Dublin 15 Ireland Ireland Active (R)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide 419-800-1 - 2019 View substance registered dossier
- - - - (R)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide 419-800-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Danish competent national authority. - - Active (R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)-benzonitrile hemisulfate 430-790-6 - - View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active (R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)-benzonitrile hemisulfate 430-790-6 - 2015 View substance registered dossier
H. Lundbeck A/S Ottiliavej 7-9 2500 Copenhagen Denmark Denmark Active (R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)-benzonitrile hemisulfate 430-790-6 - 2015; 2018 View substance registered dossier
Plixxent B.V. Korte Groningerweg 1A 9607 Foxhol Netherlands Netherlands Active (Reaction product of 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol, 2-(2-hydroxyethylamino)ethanol and formaldehyde), propoxylated 926-000-9 - 2013; 2016; 2017; 2018; 2021; 2022 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active (RS)-3-dichloroacetyl-5-(2-furanyl)-2,2-dimethyloxazolidine 434-800-1 - - View substance registered dossier
Bayer Agriculture bvba Scheldelaan 460 B-2040 Antwerp Belgium Belgium Cease Manufacture (RS)-3-dichloroacetyl-5-(2-furanyl)-2,2-dimethyloxazolidine 434-800-1 - 2020 View substance registered dossier
Bábolna Bioenvironmental Centre Private Limited Company Szállás u. 6. H-1107 Budapest Hungary Hungary Active (S) (2Z,4E)-4-carboxy-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoic acid disodium salt 918-890-2 - - View substance registered dossier
Carbogen Amcis Ltd 303 Clayton Lane M11 4SX Manchester Greater Manchester United Kingdom United Kingdom No longer Valid (S)-(-)-tetrahydro-2-furoic acid 433-770-5 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (S)-(-)-tetrahydro-2-furoic acid 433-770-5 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (S)-1,2,4-butanetriyltrimethanesulfonate 433-850-1 - - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (S)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole Tartrat Trihydrate 928-472-1 - 2021 View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Cease Manufacture (S)-2-(1-aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one hydrochloride 942-180-1 - 2017 View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active (S)-2-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid 951-381-3 - 2021 View substance registered dossier
[Confidential] - - - (S)-2-(5-Methylheteromonocycle-2-carboxamido)-alkenoic acid - - - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active (S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid 439-640-4 - 2019; 2020; 2022 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid 439-640-4 - - View substance registered dossier
Roche Pharma AG (1) Emil-Barell-Strasse 1 79639 Grenzach-Wyhlen Germany Germany Cease Manufacture (S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid 439-640-4 - 2019 View substance registered dossier
B-Lands Consulting (811587-0) World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France France Active (S)-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid 431-910-1 - - View substance registered dossier
[Confidential] - - - (S)-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid 431-910-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - No longer Valid (S)-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid 431-910-1 - 2022 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (S)-3-[1-(Dimethylamino)ethyl]-phenol 478-670-2 - - View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active (S)-3-[1-(Dimethylamino)ethyl]-phenol 478-670-2 - 2010 View substance registered dossier
- - - - (S)-3-[5-(4-Fluorophenyl)-1,5-dioxopentyl]-4-phenyloxazolidin-2-one 480-320-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (S)-3-[5-(4-Fluorophenyl)-1,5-dioxopentyl]-4-phenyloxazolidin-2-one 480-320-9 - - View substance registered dossier
[Confidential] - - - (S)-3-[5-(4-Fluorophenyl)-1,5-dioxopentyl]-4-phenyloxazolidin-2-one 480-320-9 - - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (S)-3-[5-(4-Fluorophenyl)-1,5-dioxopentyl]-4-phenyloxazolidin-2-one 480-320-9 - - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture (S)-3-Hydroxytetrahydrofurane 425-090-2 - 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - No longer Valid (S)-3-Hydroxytetrahydrofurane 425-090-2 - 2022 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (S)-3-Hydroxytetrahydrofurane 425-090-2 - - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active (S)-3-Hydroxytetrahydrofurane 425-090-2 - 2017 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (S)-3-Hydroxytetrahydrofurane 425-090-2 - 2017 View substance registered dossier
- - - - (S)-4-amino-5-[(2-(1H-imidazol-4-yl)ethyl)amino]-5-oxopentanoic acid 421-900-3 - - View substance registered dossier
bracco imaging Via Folli 50 20134 milan Italy Italy Active (S)-5-[2-(acetyloxy)propanamido]-2,4,6-triiodo-1,3-di(chloroformyl)benzene 410-940-7 - 2022 View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (S)-5-chloro-4-methyl-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole dihydrochloride 948-271-2 - - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Cease Manufacture (S)-6-(2-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-2-oxoethyl) 5-tert-butyl 5-azaspiro[2.4]heptane-5,6-dicarboxylate 941-125-9 - 2021 View substance registered dossier
- - - - (S)-7-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one glucopyranosyl ether 471-940-0 - - View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active (S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle 439-220-0 - - View substance registered dossier
- - - - (S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle 439-220-0 - - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate 445-820-3 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate 445-820-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - No longer Valid (S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate 445-820-3 - 2022 View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid (S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate 445-820-3 - 2021 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (S)-ethyl-3-amino-3-phenylpropanoate hemi (2S,3S)-2,3-dihydroxysuccinate 955-403-2 - - View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia Croatia Active (S)-N-[[3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-amine 942-077-1 - - View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active (S)-propane-1,2-diamine bis((2S,3S)-2,3-dihydroxysuccinate) dihydrate 924-425-4 - - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (S)-propane-1,2-diamine bis((2S,3S)-2,3-dihydroxysuccinate) dihydrate 924-425-4 - - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Cease Manufacture (S)-tert-butyl(1-((3-fluoro-2-(phenylcarbamoyl)phenyl)amino)-1-oxobutan-2 yl)carbamate 942-159-7 - 2017 View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (S)-tert.-Butyl-[2-(aminoethoxy)-[1,2]oxaborolan-4-yl]acetate 942-682-0 - - View substance registered dossier
Bábolna Bioenvironmental Centre Private Limited Company Szállás u. 6. H-1107 Budapest Hungary Hungary Active (S)Ammonium-(2E,4E)-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate 926-381-1 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active (trans(trans))-4'-but-3-enyl-4-(4-methylphenyl)-bicyclohexyl 429-580-7 - 2010; 2020 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active (trans(trans))-4'-vinyl-4-(4-methylphenyl)bicyclohexyl 439-730-3 - 2009; 2010; 2011; 2012; 2014; 2019 View substance registered dossier
ABCR Laboratorios, S.L. Poligono Industrial de Vilapouca 36555 Forcarei Galicia Spain Spain Active (Trimethoxysilyl)methyl 2-methacrylate 454-220-0 - - View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active (Trimethoxysilyl)methyl 2-methacrylate 454-220-0 - 2016 View substance registered dossier
Nouryon Functional Chemicals B.V. Haaksbergweg 88 1101 BZ Amsterdam The Netherlands Netherlands Netherlands Cease Manufacture (TRIMETHYLENEDINITRILO)TETRAKISACETONITRILE 429-330-7 - 2014 View substance registered dossier
- - - - (trimethylvinylsilyl)hexafluoroacetylacetonato copper I 435-140-5 - - View substance registered dossier
ALCOVER QUIMICA S.L. CARRETERA MONTBLANC Km 24 43460 ALCOVER Spain Spain Active (xylenes and 4-ethylbenzene)sulfonic acids 701-247-3 - 2018 View substance registered dossier
Habrinol Decin Tovarni 63 407 11 Decin XXXII Decin Czech Republic Czech Republic Active (xylenes and 4-ethylbenzene)sulfonic acids 701-247-3 - 2019; 2023 View substance registered dossier
Innospec Performance Chemicals France SAS Zone Industrielle de Han Sur Meuse BP19 55300 Saint-Mihiel France France Active (xylenes and 4-ethylbenzene)sulfonic acids 701-247-3 - 2017; 2018; 2022 View substance registered dossier
PHARMEGIC HEALTHCARE LIMITED 6th Floor, Konstitucijos av. 21A, 08130 Vilnius Lithuania Ireland Ireland Active (xylenes and 4-ethylbenzene)sulfonic acids 701-247-3 - - View substance registered dossier
STEPAN EUROPE SAS OR chemin Jongkind CS 20127 38341 VOREPPE France France Active (xylenes and 4-ethylbenzene)sulfonic acids 701-247-3 - 2018; 2021 View substance registered dossier
Experien Chemical Services (Ireland) Limited Unit 3D North Point House North Point Business Park, New Mallow Road TS23 AT2P Cork Ireland Ireland Active (xylenes and 4-ethylbenzene)sulfonic acids 701-247-3 - 2019; 2021 View substance registered dossier
Charles River Laboratories Den Bosch B.V. OR63 Hambakenwetering 7 5231DD 's-Hertogenbosch Netherlands Netherlands Active (xylenes and 4-ethylbenzene)sulfonic acids 701-247-3 - 2019 View substance registered dossier
CAVENAGHI SPA via Varese 19 20020 lainate Italy Italy Active (xylenes and 4-ethylbenzene)sulfonic acids 701-247-3 - 2019 View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (Z)-3-(chloro((2-hydroxy-3-(piperidin-1-yl)propoxy)imino)methyl)pyridine 1-oxide 953-723-7 - - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (Z)-4-[C11-13 (branched) alkylamino]-4-oxo-2-butenoic acid 701-116-0 - 2013; 2016; 2017; 2020; 2021; 2022 View substance registered dossier
[Confidential] - - - (Z)-4-[C11-13 (branched) alkylamino]-4-oxo-2-butenoic acid 701-116-0 - - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (Z)-5-Amino-α-(methoxyimino)-1,2,4-thiadiazole-3-acetic acid 456-150-6 - 2021 View substance registered dossier
Sabinsa Europe GmbH Monzastrasse 4 63225 Langen Hessen Germany Germany Active (Z)-but-2-enedioic acid;N-[2-(dimethylamino)ethyl]-5-(dithiolan-3-yl)pentanamide 922-363-2 - - View substance registered dossier
Nalco Española Manufacturing S.L.U. Pedro i Pons 9 - 11 Planta 11 08034 Barcelona Spain Spain Active (Z)-N-(3-ammoniopropyl)-N'-[3-octadecenylamino)propyl]propane-1,3-diaminium acetate 700-802-7 - - View substance registered dossier
Ecolab Production France SAS 94 Avenue Du General Patton Chalons-En-Champagne 51000 Chalons-En-Champagne France France Active (Z)-N-(3-ammoniopropyl)-N'-[3-octadecenylamino)propyl]propane-1,3-diaminium acetate 700-802-7 - - View substance registered dossier
Ecolab Production Belgium B.V.B.A. Havenlaan 4 3980 Tessenderlo Belgium Belgium Active (Z)-N-(3-ammoniopropyl)-N'-[3-octadecenylamino)propyl]propane-1,3-diaminium acetate 700-802-7 - 2012 View substance registered dossier
Nalco Española Manufacturing S.L.U. Pedro i Pons 9 - 11 Planta 11 08034 Barcelona Spain Spain Active (Z)-N-(3-ammoniopropyl)-N'-octadecenylpropane-1,3-diaminium acetate 700-764-1 - - View substance registered dossier
Ecolab A.E. Fleming Street 15 GR-15123 Maroussi, Athens Greece Greece Active (Z)-N-(3-ammoniopropyl)-N'-octadecenylpropane-1,3-diaminium acetate 700-764-1 - - View substance registered dossier
Ecolab Production Belgium B.V.B.A. Havenlaan 4 3980 Tessenderlo Belgium Belgium Active (Z)-N-(3-ammoniopropyl)-N'-octadecenylpropane-1,3-diaminium acetate 700-764-1 - - View substance registered dossier
Ecolab Production Italy s.r.l. Via Grandi 9/11 20089 Rozzano Italy Italy Active (Z)-N-(3-ammoniopropyl)-N'-octadecenylpropane-1,3-diaminium acetate 700-764-1 - - View substance registered dossier
Ecolab D.O.O. Vajngerlova Ulica 4 SL-2000 Maribor Slovenia Slovenia Active (Z)-N-(3-ammoniopropyl)-N'-octadecenylpropane-1,3-diaminium acetate 700-764-1 - - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active ({4-(3-Chloro-4-fluoro-phenylamino)-7-[(S)-(tetrahydro-furan-3-yl)oxy]-quinazolin-6-ylcarbamoyl}-methyl)-phosphonic acid diethyl ester 928-634-1 - 2021 View substance registered dossier
United Initiators GmbH Dr. Gustav-Adolph-Str. 3 D-82049 Pullach Bavaria Germany Germany Active 1,1'-(2,3-dimethylbutane-2,3-diyl)bis[4-(propan-2-yl)benzene] 449-400-0 - 2013; 2016 View substance registered dossier
LEVACO Chemicals GmbH CHEMPARK 51368 Leverkusen Germany Germany Active 1,1'-(dodecylimino)dipropan-2-ol + 1,1'-(tetradecylimino)dipropan-2-ol 911-174-0 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - No longer Valid 1,1'-(methylenedi-4,1-phenylene)bis(3-butylurea) 416-600-4 - 2022 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Danish competent national authority. - - No longer Valid 1,1'-(methylenedi-4,1-phenylene)bis(3-butylurea) 416-600-4 - 2022 View substance registered dossier
Sika Deutschland GmbH Kornwestheimer Str. 103 - 107 70439 Stuttgart Germany Germany Active 1,1'-(methylenedi-4,1-phenylene)bis(3-butylurea) 416-600-4 - 2013; 2016; 2019; 2020 View substance registered dossier
SIKA France SA 101 Rue de Tolbiac B.P. 377 75626 Paris Cédex 13 France France Active 1,1'-(methylenedi-4,1-phenylene)bis(3-butylurea) 416-600-4 - 2010; 2011; 2013; 2016; 2019; 2020 View substance registered dossier
BOSTIK S.A. 420, rue d’Estienne d’Orves 92705 Colombes Cedex France France France Active 1,1'-(methylenedi-4,1-phenylene)bis(3-butylurea) 416-600-4 - 2020 View substance registered dossier
Sika Polyurethane Manufacturing S.R.L. Via Crosa 23/31 Sede in Cerano 28065 Cerano (NO) Italy Italy Active 1,1'-(methylenedi-4,1-phenylene)bis(3-butylurea) 416-600-4 - 2013; 2016; 2019; 2020 View substance registered dossier
Sika Deutschland GmbH - OR Sika Manufacturing AG Kornwestheimer Str. 103-107 70439 Stuttgart Germany Germany Active 1,1'-(methylenedi-4,1-phenylene)bis(3-butylurea) 416-600-4 - 2011; 2013; 2016; 2018; 2019; 2020 View substance registered dossier
Bostik AB Strandbadsvägen 22 251 09 Helsingborg Sweden Sweden Active 1,1'-(methylenedi-4,1-phenylene)bis(3-butylurea) 416-600-4 - 2010; 2011; 2021 View substance registered dossier
N.P.T. S.R.L. a Socio Unico Via Guido Rossa 2 40053 Valsamoggia- Loc. Crespellano Italy Italy Active 1,1'-(methylenedi-4,1-phenylene)bis(3-butylurea) 416-600-4 - 2020 View substance registered dossier
Nouryon Functional Chemicals B.V. Haaksbergweg 88 1101 BZ Amsterdam The Netherlands Netherlands Netherlands Active 1,1'-[propane-1,3-diylbis(oxy)]bis(2-bromo-4-tert-butylbenzene) 925-064-5 - 2019 View substance registered dossier
PALCHEM Rue du Transvaal BP22 62143 ANGRES France France Active 1,1'-[propane-1,3-diylbis(oxy)]bis(2-bromo-4-tert-butylbenzene) 925-064-5 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 1,1'-Biphenyl, 4'-butyl-3-fluoro- 935-978-6 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 1,1'-bis(diphenylphosphino) ferrocene 430-420-3 - - View substance registered dossier
Huntsman (Europe) BV - OR2 Everslaan 45 B-3078 Everberg Belgium Belgium Active 1,1'-Methylenebis(4-isocyanatobenzene) and 1,1'-methylenebis(4-isocyanatobenzene) homopolymer and their reaction products with [(methylethylene)bis(oxy)]dipropanol and butane-1,3-diol and propane-1,2-diol 701-393-8 - 2017; 2019; 2021 View substance registered dossier
HUNTSMAN HOLLAND BV Merseyweg 10 3197 KG Botlek-Rotterdam Netherlands Netherlands Active 1,1'-Methylenebis(4-isocyanatobenzene) and 1,1'-methylenebis(4-isocyanatobenzene) homopolymer and their reaction products with [(methylethylene)bis(oxy)]dipropanol and butane-1,3-diol and propane-1,2-diol 701-393-8 - 2011; 2012; 2013; 2015; 2019; 2021 View substance registered dossier
BASF Polyurethanes GmbH Elastogranstr. 60 49448 Lemförde Niedersachsen Germany Germany Active 1,1'-Methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with [(methylethylene)bis(oxy)]dipropanol 701-124-4 - 2012; 2019 View substance registered dossier
DOW DEUTSCHLAND ANLAGENGESELLSCHAFT mbH Buetzflether Sand 2 D-21683 Stade Germany Germany Active 1,1'-Methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with [(methylethylene)bis(oxy)]dipropanol 701-124-4 - 2022 View substance registered dossier
DOW BENELUX B.V. Postbus 48 4530 AA Terneuzen Netherlands Netherlands Active 1,1'-Methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with [(methylethylene)bis(oxy)]dipropanol 701-124-4 - 2013; 2014; 2016; 2019; 2022 View substance registered dossier
Covestro Deutschland AG OR US_001257 Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany Germany Active 1,1'-Methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with [(methylethylene)bis(oxy)]dipropanol 701-124-4 - 2012; 2017; 2019; 2021 View substance registered dossier
PLIXXENT GmbH & Co. KG Mittelkamp 112 26125 Oldenburg Germany Germany Cease Manufacture 1,1'-Methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with [(methylethylene)bis(oxy)]dipropanol 701-124-4 - 2022 View substance registered dossier
DOW ITALIA S.R.L. Via F. Albani 65 20148 Milano Italy Italy Active 1,1'-Methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with [(methylethylene)bis(oxy)]dipropanol 701-124-4 - 2019; 2022 View substance registered dossier
COVESTRO, S.L. C/. Feixa LLarga, 7 08040 Barcelona Spain Spain Active 1,1'-Methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with [(methylethylene)bis(oxy)]dipropanol 701-124-4 - 2019; 2021 View substance registered dossier
Covestro Deutschland AG Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany Germany Active 1,1'-Methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with [(methylethylene)bis(oxy)]dipropanol 701-124-4 - 2012; 2014; 2016; 2017; 2018; 2019; 2021 View substance registered dossier
BASF Espanola S.L. Calle Can Ràbia, n. 3-5 8017 Barcelona Spain Spain Active 1,1'-Methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with [(methylethylene)bis(oxy)]dipropanol 701-124-4 - 2012; 2019 View substance registered dossier
Huntsman International (Italy) Via Mazzini 58 21020 Ternate Italy Italy Cease Manufacture 1,1'-Methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with [(methylethylene)bis(oxy)]dipropanol 701-124-4 - 2021 View substance registered dossier
BASF Italia S.p.A. Via Marconato 8 20811 Cesano Maderno Italy Italy Active 1,1'-Methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with [(methylethylene)bis(oxy)]dipropanol 701-124-4 - 2012; 2019 View substance registered dossier
HUNTSMAN HOLLAND BV Merseyweg 10 3197 KG Botlek-Rotterdam Netherlands Netherlands Active 1,1'-methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with butane-1,3-diol, 2,2'-oxydiethanol and propane-1,2-diol 701-173-1 - 2011; 2012; 2013; 2014; 2019; 2021 View substance registered dossier
HUNTSMAN HOLLAND BV Merseyweg 10 3197 KG Botlek-Rotterdam Netherlands Netherlands Active 1,1'-Methylenebis(4-isocyanatobenzene) and oligomeric reaction products of 1,1'-methylenebis(4-isocyanatobenzene) and oxydipropanol 701-040-8 - 2011; 2012; 2013; 2014; 2019; 2021 View substance registered dossier
BorsodChem Zrt. - OR Bolyai ter 1. H-3700 Kazincbarcika Hungary Hungary Active 1,1'-Methylenebis(4-isocyanatobenzene) and oligomeric reaction products of 1,1'-methylenebis(4-isocyanatobenzene) and oxydipropanol 701-040-8 - 2012; 2013; 2014; 2015; 2019 View substance registered dossier
BorsodChem Bolyai ter 1 3700 Kazincbarcika Hungary Hungary Active 1,1'-Methylenebis(4-isocyanatobenzene) and oligomeric reaction products of 1,1'-methylenebis(4-isocyanatobenzene) and oxydipropanol 701-040-8 - 2012; 2013; 2014; 2019; 2021 View substance registered dossier
BASF Antwerpen N.V. Haven 725, Scheldelaan 600 2040 Antwerpen 4 Antwerpen Belgium Belgium Active 1,1'-Methylenebis(4-isocyanatobenzene) and oligomeric reaction products of 1,1'-methylenebis(4-isocyanatobenzene) and oxydipropanol and oligomerization reaction products of oxydipropanol 701-041-3 - 2012; 2014; 2017; 2019; 2021 View substance registered dossier
BASF Espanola S.L. Calle Can Ràbia, n. 3-5 8017 Barcelona Spain Spain Active 1,1'-Methylenebis(4-isocyanatobenzene) and oligomeric reaction products of 1,1'-methylenebis(4-isocyanatobenzene) and oxydipropanol and oligomerization reaction products of oxydipropanol 701-041-3 - 2014; 2018 View substance registered dossier
BASF Polyurethanes GmbH Elastogranstr. 60 49448 Lemförde Niedersachsen Germany Germany Active 1,1'-Methylenebis(4-isocyanatobenzene) and oligomeric reaction products of 1,1'-methylenebis(4-isocyanatobenzene) and oxydipropanol and oligomerization reaction products of oxydipropanol 701-041-3 - 2012; 2014; 2018 View substance registered dossier
BASF Italia S.p.A. Via Marconato 8 20811 Cesano Maderno Italy Italy Active 1,1'-Methylenebis(4-isocyanatobenzene) and oligomeric reaction products of 1,1'-methylenebis(4-isocyanatobenzene) and oxydipropanol and oligomerization reaction products of oxydipropanol 701-041-3 - 2014; 2018 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active 1,1'-{2-(2,4-difluorophenyl)-2-[(trimethylsilyl)oxy]propane-1,3-diyl}bis(1H-1,2,4-triazole) 928-141-1 - 2018; 2021 View substance registered dossier
Chr. Olesen ChemPharm GmbH Innungsstr. 3 21244 Buchholz Germany Germany Active 1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluorotetradecane 432-570-5 - - View substance registered dossier
AGC Chemicals Europe, Ltd World Trade Centre Zuidplein 80 1077XV Amsterdam Netherlands Netherlands Active 1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluorotetradecane 432-570-5 - - View substance registered dossier
FLC Industries Sp. z o.o. ul. Energetyków 9 47-225 Kędzierzyn-Koźle Poland Poland Active 1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluorotetradecane 432-570-5 - 2016 View substance registered dossier
LAXMI ORGANIC INDUSTRIES (EUROPE) B.V. BURGEMEESTER FEITHPLEIN 11 2273 BZ VOORBURG Netherlands Netherlands Cease Manufacture 1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluorotetradecane 432-570-5 - 2019 View substance registered dossier
- - - - 1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluorotetradecane 432-570-5 - - View substance registered dossier
3M Belgium BVBA/SPRL Hermeslaan 7 1831 Diegem Belgium Belgium Active 1,1,1,2,3,3-hexafluoro-4-(1,1,2,3,3,3-hexafluoropropoxy)pentane 484-290-8 - 2011 View substance registered dossier
SYNTHESIA TECHNOLOGY EUROPE S.L.U C/ Argent, 3 08755 Castellbisbal (Barcelona) Spain Spain Active 1,1,1-Tri((1,3-dioxobutoxy)-methyl)-propane 422-630-9 - 2023 View substance registered dossier
YOU Solutions Germany GmbH - REACH (part of Arxada) Freundallee 9 a 30173 Hannover Germany Germany Active 1,1,1-Tri((1,3-dioxobutoxy)-methyl)-propane 422-630-9 - 2010 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active 1,1,1-Tri((1,3-dioxobutoxy)-methyl)-propane 422-630-9 - - View substance registered dossier
- - - - 1,1,1-Tri((1,3-dioxobutoxy)-methyl)-propane 422-630-9 - - View substance registered dossier
JSC Grindeks 53 Krustpils St LV 1057 Riga Latvia Latvia Active 1,1,1-trimethyl-2-(methoxycarbonylethyl)hydrazonium bromide 463-070-5 - 2010; 2020 View substance registered dossier
Merck Performance Materials GmbH Rheingaustrasse 190-196 65203 Wiesbaden Germany Germany Cease Manufacture 1,1,1-Tris(p-hydroxyphenyl)ethane, mixed esters with 3-Diazo-3,4-dihydro-4-oxonaphthalene 2-sulphonic acid and 6-Diazo-5,6-dihydro-5-oxonaphthalene 2-sulphonic acid 422-760-6 - 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active 1,1,2,2,3,3,4,4,4-nonafluoro-N,N-bis(2-hydroxyethyl)-1-butanesulfonamide 454-680-2 - - View substance registered dossier
3M Belgium BVBA/SPRL (OR1) Hermeslaan 7 1831 Diegem Belgium Belgium Active 1,1,2,2,3,3-hexafluoro-1-trifluoromethoxy-3-trifluorovinyloxypropane 442-390-9 - - View substance registered dossier
Dyneon GmbH Industrieparkstrasse 1 84508 Burgkirchen a. d. Alz Germany Germany Active 1,1,2,2,3,3-hexafluoro-1-trifluoromethoxy-3-trifluorovinyloxypropane 442-390-9 - 2014; 2018 View substance registered dossier
WeylChem Lamotte S.A.S Rue du Flottage B.P. 1 60350 Trosly Breuil France France Cease Manufacture 1,1,2,2-tetramethoxyethane 463-280-7 - 2019 View substance registered dossier
TIB Chemicals AG Muelheimer Str. 16-22 68219 Mannheim Germany Germany Active 1,1,3,3-Tetraoctyl-1-3-bis((2,2,3,5-oxotetramethylhexyl)oxy)distannoxane, dimer 947-528-6 - 2019 View substance registered dossier
- - - - 1,1-bis(4-hydroxy-2,5-dimethylphenyl)acetone 433-650-2 - - View substance registered dossier
Globalquimia, S.L.U. Avenida Diagonal, 519, 1º 1ª 08029 Barcelona Spain Spain Spain Active 1,1-cyclohexanediacetic acid monoamide 449-430-4 - 2010 View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l. Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy Italy Active 1,1-cyclohexanediacetic acid monoamide 449-430-4 - - View substance registered dossier
Menadiona SL Pol Ind Mas Puigvert, Ctra Nacional II Km 680, 5 08389 Palafolls Barcelona Spain Spain Active 1,1-cyclohexanediacetic acid monoamide 449-430-4 - 2010 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Cease Manufacture 1,1-cyclohexanediacetic acid monoamide 449-430-4 - 2017 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1,1-cyclohexanediacetic acid monoamide 449-430-4 - 2011 View substance registered dossier
Cytec Industries BV as OR for Solvay Solutions UK Limited Weena 505 3013 AL Rotterdam Rotterdam Netherlands Netherlands Netherlands Cease Manufacture 1,12-bis (diisopropyl phosphoryl) dodecane 919-645-2 - 2021 View substance registered dossier
Chemetall GmbH Trakehner Str. 3 60487 Frankfurt Germany Germany Active 1,12-DODECYLDIPHOSPHONIC ACID 435-710-3 - - View substance registered dossier
Cytec Industries BV OR for UK Burgemeester van Lierplein 75 3134 ZB Vlaardingen Netherlands Netherlands Active 1,12-DODECYLDIPHOSPHONIC ACID 435-710-3 - - View substance registered dossier
Wilmar Europe Trading B.V. Central Post – Entrance West, 7th floor Delftseplein 27G 3013 AA Rotterdam Netherlands Netherlands Active 1,18-octadecanedioic acid 442-490-2 - 2015 View substance registered dossier
Emery Oleochemicals GmbH Paul-Thomas-Straße 56 D-40599 Duesseldorf Germany Germany Active 1,18-octadecanedioic acid 442-490-2 - 2013; 2014; 2015 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 1,18-octadecanedioic acid 442-490-2 - - View substance registered dossier
BASF Espanola S.L. Calle Can Ràbia, n. 3-5 8017 Barcelona Spain Spain Active 1,18-octadecanedioic acid 442-490-2 - - View substance registered dossier
HUNTSMAN HOLLAND BV Merseyweg 10 3197 KG Botlek-Rotterdam Netherlands Netherlands Active 1,1’-Methylenebis(4-isocyanatobenzene) and its reaction products with [(methylethylene)bis(oxy)]dipropanol, butane-1,3-diol and propylene glycol 941-496-7 - 2015; 2016; 2019; 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active 1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-2-naphtalensulfonate of 1,3,5-triazine-2,4,6-triamer 433-290-6 - - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active 1,2,3,6,7,11b-HEXAHYDRO-PYRAZINO[2,1-a]ISOQUINOLIN-4-ONE 917-666-1 - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.