Registered substances
Registered substances
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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM. More
Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.
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Registered Substances Factsheets
Substances which have been registered and can be placed on the EEA market by those companies with a valid registration
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Registrant/Supplier | Address | Country | Registration Status | Name | EC / List no. | CAS no. | Last update year | Details |
---|---|---|---|---|---|---|---|---|
Miltitz Aromatics GmbH | Chemiepark Bitterfeld-Wolfen Riechstoffstrasse 1 06803 Bitterfeld-Wolfen Germany | Germany | Active | (3-Methyl-but-2-enyloxy)-benzol | 846-080-8 | 14309-15-0 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | No longer Valid | (3-Phenyl-1H-inden-1-ylidene)bis(tricyclohexylphosphine)ruthenium(IV) Dichloride Tetrahydrofuran Adduct | 480-140-0 | 250220-36-1 | 2022 | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Cease Manufacture | (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl[(methylsulfonyl)oxy]acetate | 700-396-1 | 60924-38-1 | 2012 | View substance registered dossier |
DSM Pharma Chemicals Venlo B.V. | Grubbenvorsterweg 8 Postbox 81 5900 AB Venlo Netherlands | Netherlands | Active | (3AS,4S,6AR)-4-METHOXYTETRAHYDROFURO[3,4- B]FURAN-2(3H)-ONE | 443-930-6 | - | - | View substance registered dossier |
Janssen Pharmaceutica N.V. | Turnhoutseweg 30 2340 Beerse Belgium | Belgium | Cease Manufacture | (3beta)-17-(3-pyridinyl)androsta-5,16-dien-3-yl acetate compound with (2R,3R)-tartaric acid and methanol (1 : 1 : 1.5) | 931-336-4 | - | 2019 | View substance registered dossier |
PharmaZell GmbH | Rosenheimer Straße 43 D-83064 Raubling Germany | Germany | Active | (3E)-3-[[4-(2-carboxyethylcarbamoyl)phenyl]hydrazinylidene]-6-oxocyclohexa-1,4-diene-1-carboxylic acid | 617-116-8 | 80573-04-2 | 2019 | View substance registered dossier |
PFW Aroma Ingredients B.V. | Veemweg 29-31 3771 MT Barneveld Gelderland Netherlands | Netherlands | Active | (3E)-4-[(1S,3aS,4R,7aS)-1,7a-dimethyloctahydro-4H-1,4-methanoinden-4-yl]pent-3-en-2-one | 948-498-7 | 143785-33-5 | 2019; 2022 | View substance registered dossier |
BASF SE | Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany | Germany | Active | (3R)-3-aminobutan-1-ol-(2S)-2-hydroxy-2-phenyl-acetate | 810-156-9 | 1236049-43-6 | 2016 | View substance registered dossier |
SONEAS Chemicals Ltd. | Banyaleg Str. 47-59. H-1225 Budapest Hungary | Hungary | Active | (3R)-3-methylpiperazin-2-one | 693-438-2 | 922178-61-8 | - | View substance registered dossier |
SONEAS Chemicals Ltd. | Banyaleg Str. 47-59. H-1225 Budapest Hungary | Hungary | Active | (3R)-4[(4-Methoxyphenyl)methyl]-3-methylpiperazine-2-one | 954-618-9 | - | 2022 | View substance registered dossier |
SICPA Germany GmbH | Gewerbepark Lindach D7 84489 Burghausen Germany | Germany | Active | (3R,3aR,6R,6aR)-6-[(4-{[4-(acryloyloxy)benzoyl]oxy}-3-methoxybenzoyl)oxy]hexahydrofuro[3,2-b]furan-3-yl 4-{[4-(acryloyloxy)benzoyl]oxy}-3-methoxybenzoate | 700-376-2 | 1015689-48-1 | - | View substance registered dossier |
OLEON N.V. | Industriezone "ter straten" Vaartstraat 220 2520 Oelegem Belgium | Belgium | Active | (3R,3aR,6S,6aR)-hexahydrofuro[3,2-b]furan-3,6-diyl dioctanoate | 807-840-4 | 64896-70-4 | 2015 | View substance registered dossier |
[Confidential] | - | - | - | (3R,4R,5R,6R,9R,10Z,11R,12S,14S)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione 10-oxime | 603-883-6 | 134931-01-4 | - | View substance registered dossier |
[Confidential] | - | - | - | (3R,4S,5R,6R)-3,4,5-Tris-trimethylsilanyloxy-6-trimethylsilanyloxymethyl-tetrahydro-pyran-2-on | 608-732-8 | 32384-65-9 | - | View substance registered dossier |
Hovione FarmaCiencia SA | Sete Casas 2674-506 Loures Portugal | Portugal | Cease Manufacture | (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-10-hydroxyimino-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one | 603-467-4 | 13127-18-9 | 2017 | View substance registered dossier |
Pliva Hrvatska doo | Prilaz baruna Filipovića 25 10000 Zagreb Croatia | Croatia | Active | (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-10-(hydroxyimino)-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one hydrochloride | 607-864-3 | 26116-57-4 | - | View substance registered dossier |
Sandoz Industrial Products SA | Ctra. Granollers - Cardedeu C-251, Km 4 08520 Les Franqueses del Vallés Catalunya Spain | Spain | Active | (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-10-(hydroxyimino)-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one hydrochloride | 607-864-3 | 26116-57-4 | - | View substance registered dossier |
Huvepharma Italia s.r.l. | Via Roberto Lepetit, 142 12075 GARESSIO (CN) Italy | Italy | Active | (3R,5aS,6R,8aS,9R,12S,12aR)-3,6,9-trimethyloctahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepin-10(3H)-one | 700-290-5 | 63968-64-9 | 2009; 2010; 2012 | View substance registered dossier |
MINAKEM Beuvry Production SAS | 145, Chemin des Lilas 59310 Beuvry-la-Forêt France | France | Cease Manufacture | (3R,7aR)-3-tert-butyl-1,5-dioxodihydro-1H-pyrrolo[1,2-c][1,3]oxazole-7a(5H)-carbaldehyde | 812-036-1 | 1214741-19-1 | 2019 | View substance registered dossier |
MINAKEM Beuvry Production SAS | 145, Chemin des Lilas 59310 Beuvry-la-Forêt France | France | Cease Manufacture | (3R,7aR)-3-tert-butyl-7a-{methoxy[(trimethylsilyl)oxy]methyl}dihydro-1H-pyrrolo[1,2-c][1,3]oxazole-1,5(6H)-dione | 942-823-6 | - | 2019 | View substance registered dossier |
MINAKEM Beuvry Production SAS | 145, Chemin des Lilas 59310 Beuvry-la-Forêt France | France | Cease Manufacture | (3R,7aS)-3-tert-butyldihydro-1H-pyrrolo[1,2-c]oxazole-1,5(6H)-dione | 810-392-2 | 171284-84-7 | 2019 | View substance registered dossier |
Bayer AG | Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany | Germany | Active | (3S)-3-hydroxypyrrolidin-2-one | 676-349-3 | 34368-52-0 | - | View substance registered dossier |
QUIMICA SINTETICA, S.A. | C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain | Spain | Active | (3S)-9,10-difluoro-2,3-dihidro-3-metil-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxacine-6-carboxílic acid ethyl ester | 691-244-2 | 106939-34-8 | 2014 | View substance registered dossier |
Saneca Pharmaceuticals a.s. | Nitrianska 100 92027 Hlohovec Slovakia | Slovakia | Active | (3S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine ethanedioate | 603-567-8 | 132335-47-8 | 2009 | View substance registered dossier |
Roche Ireland Limited | Clarehill . Clarecastle Ireland | Ireland | Cease Manufacture | (3S,4aS,8aS)-2-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-tert-butyldecahydroisoquinoline-3-carboxamide | 430-230-0 | 136522-17-3 | 2020 | View substance registered dossier |
Roche Ireland Limited | Clarehill . Clarecastle Ireland | Ireland | Cease Manufacture | (3S,4aS,8aS)-N-tert-Butyldecahydro-3-isoquinolinecarboxamide | 420-380-5 | 136465-81-1 | 2020 | View substance registered dossier |
CU Chemie Uetikon GmbH | Raiffeisenstrasse 4 77933 Lahr Germany | Germany | Cease Manufacture | (3S,5R,8aS)-3-phenyl-3,5,6,7,8,8a-hexahydro-2H-oxazolo[3,2-a]pyridine-5-carbonitrile | 634-598-5 | 106565-71-3 | 2020 | View substance registered dossier |
- | - | - | - | (3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol | 450-320-3 | - | - | View substance registered dossier |
Lek Pharmaceuticals d.d. | Verovskova 57 1526 Ljubljana Slovenia | Slovenia | Cease Manufacture | (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]-oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone | 610-965-5 | 53123-88-9 | 2017 | View substance registered dossier |
Santrol Europe ApS | Aagade 103 Pjedsted 7000 Fredericia Denmark | Denmark | Cease Manufacture | (3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione | 224-832-0 | 4511-42-6 | 2016 | View substance registered dossier |
IFF Benicarlo, S.L. | Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain | Spain | Active | (3Z)-hex-3-en-1-yl 2-methylprop-2-en-1-yl ether | 439-790-0 | 292605-05-1 | 2013 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (4-(6-diethylamino-2-methylpyridin-3-yl)imino-4,5-dihydro-3-methyl-1-(4-methylphenyl)-1H-pyrazol-5-one | 427-070-9 | - | - | View substance registered dossier |
Derivados Quimicos SAU | Strada Rivoltana km6/7 20053 Rodano (Milano) Lombardia Spain | Spain | Cease Manufacture | (4-Chloro-2-fluoro-phenyl)-acetonitrile | 642-783-7 | 75279-53-7 | 2020 | View substance registered dossier |
BASF SE | Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany | Germany | Active | (4-chlorophenyl)hydrazine | 214-029-3 | 1073-69-4 | 2010 | View substance registered dossier |
Fine Organics Limited | Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom | United Kingdom | No longer Valid | (4-chlorophenyl)hydrazine | 214-029-3 | 1073-69-4 | 2018 | View substance registered dossier |
Fine Organics Limited | Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom | United Kingdom | No longer Valid | (4-hydrazinophenyl)-N-methylmethanesulfonamide hydrochloride | 406-090-1 | 81880-96-8 | 2021 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | No longer Valid | (4-methylphenyl)mesitylene sulfonate | 407-530-5 | 67811-06-7 | 2022 | View substance registered dossier |
MINAKEM Beuvry Production SAS | 145, Chemin des Lilas 59310 Beuvry-la-Forêt France | France | Active | (4-nitrophenyl)methanesulfonyl chloride | 609-806-2 | 4025-75-6 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. | - | - | Active | (4-nitrophenyl)methyl [6R,(6α,7β)]-[3-hydroxy-5,8-dioxo-7-(phenoxyacetylamino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate] | 411-820-7 | - | - | View substance registered dossier |
FujiFilm Manufacturing Europe BV | Oudenstaart 1 5047 TK Tilburg Netherlands | Netherlands | Active | (4-vinylphenyl)methyl-2-[(1Z)-1-aza-3-methyl-2-(4-methylthiophenyl)-3-morpholin-4-ylbut-1-enyloxy]acetate | 453-050-4 | - | 2011 | View substance registered dossier |
Labcorp Development SA 163 | Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 -5 Planta 28050 Madrid Spain | Spain | Active | (4aR,5S,8R,8aS)-1,2,3,4,4a,5,8,8a-octahydro-1,4:5,8-dimethanonaphthalene | 700-678-4 | - | 2019; 2020 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. | - | - | Active | (4As-cis-)-6-benzyl-octahydropyrrolo(3.4-b)pyridine | 425-930-8 | 151213-39-7 | - | View substance registered dossier |
- | - | - | - | (4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one | 433-160-9 | - | - | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Active | (4R,12aS)-7-Benzyloxy-N-[(2,4-difluorophenyl)methyl]-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide | 809-887-6 | 1206102-11-5 | - | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Active | (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide | 809-888-1 | 1051375-16-6 | - | View substance registered dossier |
LusoChimica S.p.A. | Via Giotto, 9 23871 Lomagna (Lecco) Italy | Italy | Active | (4S)-1-[(2S)-3-(benzoylthio)-2-methyl-1-oxopropyl]-4-(phenylthio)-L-proline potassium salt | 617-274-8 | 81938-42-3 | - | View substance registered dossier |
Isobionics B.V. | Urmonderbaan 22 6167 RD Geleen Netherlands | Netherlands | Active | (4S)-1-methyl-4-(6-methylhepta-1,5-dien-2-yl)cyclohexene | 610-461-5 | 495-61-4 | - | View substance registered dossier |
QUIMICA SINTETICA, S.A. | C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain | Spain | Active | (4S)-2-(4-bromophenyl)-4-isopropyl-3-pentanoyl-1,3-oxazolidin-5-one | 700-586-4 | 852212-81-8 | - | View substance registered dossier |
Bayer AG | Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany | Germany | Active | (4S)-3-carbamoyl-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridin-1-ium (2S,3S)-2,3-bis(benzoyloxy)-3-carboxypropanoate | 947-346-7 | - | 2020; 2021; 2023 | View substance registered dossier |
Siegfried St. Vulbas SAS | 530, allée de la Luye 01150 SAINT VULBAS France | France | Active | (4S)-4-amino-5-benzyloxy-5-oxo-pentanoic acid | 692-605-7 | 13030-09-6 | - | View substance registered dossier |
Amino Chemicals Ltd | Industrial Estate, A61 MRS3000 Marsa Malta | Malta | Active | (4S)-4-cyclohexyl-L-proline | 600-406-3 | 103201-78-1 | - | View substance registered dossier |
Fine and Performance Chemicals Ltd | Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom | United Kingdom | No longer Valid | (4S)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4,4a,7a-tetrahydrothieno[3,2-e]thiazine-6-sulfonamide | 807-123-6 | 154127-42-1 | 2021 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (4S)-4-hydroxyoxolan-2-one | 434-990-4 | 7331-52-4 | - | View substance registered dossier |
[Confidential] | - | - | - | (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide dihydrochloride | 611-780-2 | 59046-78-5 | - | View substance registered dossier |
Cipan - Companhia Industrial Produtora de Antibióticos | Rua da Estação, 42 Vala do Carregado 2600-726 Castanheira do Ribatejo Lisboa Portugal | Portugal | Active | (4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide p-toluenesulfonate | 947-931-7 | - | - | View substance registered dossier |
Cipan - Companhia Industrial Produtora de Antibióticos | Rua da Estação, 42 Vala do Carregado 2600-726 Castanheira do Ribatejo Lisboa Portugal | Portugal | Active | (4S,4aS,5aS,6S,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide di(4-chlorobenzenesulfonic acid) | 925-915-0 | - | - | View substance registered dossier |
Sanofi S.R.L. | Viale Luigi Bodio n. 37/b 20158 Milano Italy | Italy | Active | (4S,7S,12bR)-7-amino-1,2,3,4,6,7,8,12b-octahydro-6-oxobenzo(c)pyrido(1,2-a)azepin-4-carbonic acid | 443-440-2 | - | - | View substance registered dossier |
PROCOS SpA | via Matteotti 249 28062 Cameri Piemonte Italy | Italy | Active | (4Z)-3-ammoniomethyl-4-(methoxyimino)pyrrolidinium dimethanesulfonate | 608-799-3 | 329181-36-4 | - | View substance registered dossier |
ESIM Chemicals GmbH | St.-Peter-Strasse 25 4020 Linz Austria | Austria | Cease Manufacture | (4Z)-3-methyl-N-nitro-5-{[2-(phenylsulfanyl)-1,3-thiazol-5-yl]methyl}-1,3,5-oxadiazinan-4-imine | 427-600-9 | 192439-46-6 | 2022 | View substance registered dossier |
Givaudan France SAS - OR1 | 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France | France | Active | (4Z)-hept-4-en-2-yl salicylate | 700-488-1 | 873888-84-7 | - | View substance registered dossier |
Novartis Ringaskiddy Limited | . . Ringaskiddy County Cork Ireland | Ireland | Cease Manufacture | (5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid | 700-141-4 | 117570-53-3 | 2015 | View substance registered dossier |
Curia France SAS | ZI de Laville 47240 BON-ENCONTRE France | France | Active | (5-bromo-2-chloro-pyrimidin-4-yl)-cyclopentylamine | 800-067-3 | 733039-20-8 | - | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Active | (5-chloro-2-methoxyphenyl)boronic acid | 923-256-3 | - | - | View substance registered dossier |
KTR Europe GmbH | Mergenthalerallee 77 D-65760 Eschborn Germany | Germany | Active | (5R)-5-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-3-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,5-dihydrofuran-2-one | 425-980-0 | 129499-78-1 | - | View substance registered dossier |
Siegfried PharmaChemikalien Minden GmbH | Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany | Germany | Active | (5α)-4,5-epoxy-17-methyl-6-oxomorphinan-3,14-diyl diacetate | 264-989-2 | 64643-76-1 | - | View substance registered dossier |
Aspen Oss BV | Kloosterstraat 6 5349 AB Oss Netherlands | Netherlands | Cease Manufacture | (5α)-Androsta-2,16-dien-17-yl acetate | 610-545-1 | 50588-42-6 | 2019 | View substance registered dossier |
Eli Lilly Kinsale Limited | Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland | Ireland | Active | (6-amino-2-pyridyl)-(1-methyl-4-piperidyl)methanone;dihydrate;dihydrochloride | 842-055-0 | 2356133-42-9 | - | View substance registered dossier |
Sterling Pharma Solutions Ltd | Dudley NE23 7QG Cramlington Northumberland United Kingdom | United Kingdom | No longer Valid | (6-Bromo-2-pyridinyl)(4-methylphenyl)methanone | 618-079-0 | 87848-95-1 | 2021 | View substance registered dossier |
[Confidential] | - | - | - | (6-hydroxynaphthalen-2-yl)boronic acid | 687-349-8 | 173194-95-1 | - | View substance registered dossier |
Bayer AG | Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany | Germany | Active | (6-morpholin-4-ylpyrimidin-4-yl)hydrazine | 691-196-2 | 5767-36-2 | - | View substance registered dossier |
Glaxo Operations UK | Glaxo Wellcome House Berkeley Avenue UB6 0NN Greenford Middlesex United Kingdom | United Kingdom | No longer Valid | (6a,8xi,11b,14xi,16a)-6,9-difluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4- dien-21-yl benzoate | 938-716-9 | - | 2021 | View substance registered dossier |
ACS DOBFAR S.p.A | Viale Addetta 4/12 20067 Tribiano Milano Italy | Italy | Active | (6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3) | 939-998-6 | - | - | View substance registered dossier |
Sandoz GmbH | Biochemiestr. 10 6250 Kundl Austria | Austria | Cease Manufacture | (6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylic acid, 1-butylammonium salt | 439-350-8 | - | 2021 | View substance registered dossier |
ACS DOBFAR S.p.A | Viale Addetta 4/12 20067 Tribiano Milano Italy | Italy | Active | (6R,7R)-3-chloromethyl-7-{(Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)2-[(1-carboxy-1-methylethoxy)imino]acetylamino}-8-oxo-5-thia-1-azbicyclo[4.2.0]oct-2-ene-2-carboxylic acid p-methoxybenzyl ester | 939-996-5 | 689294-28-8 | 2014 | View substance registered dossier |
Sandoz GmbH | Biochemiestr. 10 6250 Kundl Austria | Austria | Cease Manufacture | (6R,7R)-7-amino-3-(5H-imidazo[1,2-b]pyridazin-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydroiodide | 606-382-0 | 197897-11-3 | 2021 | View substance registered dossier |
Sandoz GmbH | Biochemiestr. 10 6250 Kundl Austria | Austria | Active | (6R,7R)-7-Amino-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4,2,0]oct-2-ene-2-carboxylic acid | 438-350-5 | 79349-82-9 | 2010 | View substance registered dossier |
Sandoz GmbH | Biochemiestr. 10 6250 Kundl Austria | Austria | Cease Manufacture | (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | 700-301-3 | 69739-16-8 | 2021 | View substance registered dossier |
Teva Czech Industries s.r.o. | Ostravska 29/305 74770 Opava - Komarov Czech Republic | Czech Republic | Active | (6R,7R,14S)-17-cyano-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethano-17-normorphine | 921-415-1 | - | - | View substance registered dossier |
Teva Czech Industries s.r.o. | Ostravska 29/305 74770 Opava - Komarov Czech Republic | Czech Republic | Active | (6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethanomorphine | 918-453-6 | - | - | View substance registered dossier |
Teva Czech Industries s.r.o. | Ostravska 29/305 74770 Opava - Komarov Czech Republic | Czech Republic | Active | (6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-6-O-methyl-6,14-ethano-17-normorphine | 917-585-1 | - | - | View substance registered dossier |
Sandoz GmbH | Biochemiestr. 10 6250 Kundl Austria | Austria | Cease Manufacture | (6R-trans)-1-((7-Ammonio-2-carboxylato-8-oxo-5-thia-1-azabicyclo-(4.2.0)oct-2-en-3-yl)methyl)pyridinium iodide | 423-260-0 | 100988-63-4 | 2021 | View substance registered dossier |
Sanofi Aventis Deutschland GmbH | Industriepark Höchst H 831 (Room A0472) z.Hd. Hr. Dr. Schwind 65926 Frankfurt am Main Germany | Germany | Active | (6R-trans)-7-amino-3-[([5-(carboxymethyl)-4-methyl-2-thiazolyl]thio)methyl]-8-oxo- 5-thia-1-azabicyclo-[4.2.0]oct-2-en-2-carboxylic acid | 403-690-5 | 111298-82-9 | - | View substance registered dossier |
Sandoz GmbH | Biochemiestr. 10 6250 Kundl Austria | Austria | Cease Manufacture | (6R-trans)-7-amino-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | 619-847-8 | 111298-82-9 | 2021 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide | 431-140-4 | - | - | View substance registered dossier |
F.I.S. Fabbrica Italiana Sintetici S.p.a. | Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy | Italy | Active | (6S,12aR)-3,10-Dibromo-12,12a-dihydro-6-phenyl-6H-indolo[1,2-c][1,3]benzoxazine | 813-155-1 | 1585969-16-9 | - | View substance registered dossier |
Sandoz GmbH | Biochemiestr. 10 6250 Kundl Austria | Austria | Cease Manufacture | (6S,7S)-7-Amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | 435-680-1 | - | 2021 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. | - | - | Active | (6β)-6,19-epoxyandrost-4-ene-3,17-dione | 433-490-3 | 6563-83-3 | - | View substance registered dossier |
EGIS Pharmaceuticals PLC | Keresztúri út 30-38 H-1106 Budapest Hungary | Hungary | Active | (7-methoxynaphthalen-1-yl)acetonitrile | 461-670-1 | - | - | View substance registered dossier |
ORIL INDUSTRIE | 13 rue Auguste Desgenétais 76210 BOLBEC France | France | Active | (7-methoxynaphthalen-1-yl)acetonitrile | 461-670-1 | - | - | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Active | (7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate | 642-947-8 | 415927-29-6 | - | View substance registered dossier |
Gedeon Richter Plc. | Gyomroi ut 19-21 1103 Budapest Hungary | Hungary | Active | (8R,9S,13S,14S)-3-(Benzyloxy)-13-methyl-6,7,8,9,11,12,13,14 ,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,2`-[1,3]dioxolane] | 844-245-9 | 162784-26-1 | - | View substance registered dossier |
Gedeon Richter Plc. | Gyomroi ut 19-21 1103 Budapest Hungary | Hungary | Active | (8R,9S,13S,14S)-3-benzyloxy)-13-methyl-6,7,8,9,11,12,13,14- octahydrospiro[cyclopenta[a]phenanthrene-17,2`[1,3]dioxolane] | 844-243-8 | 534572-67-3 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. | - | - | Active | (9S)-9-amino-9-deoxyerythromycin | 406-790-7 | 26116-56-3 | - | View substance registered dossier |
Sicor - Società Italiana Corticosteroidi S.r.l. | Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy | Italy | Active | (9β,11β,16α)-9,11-epoxy-21-hydroxy-16, 17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione | 609-736-2 | 39672-75-8 | - | View substance registered dossier |
Archroma Italy, S.r.l. - OR | Via Manzoni 37 20030 Palazzolo Milanese Italy | Italy | Cease Manufacture | (Benzyloxycarbonyl)methyl 3-[5-acetamido-4-(2-chloro-4,6-dinitrophenylazo)-2-methoxyanilino]propionate | 436-000-6 | 159010-67-0 | 2017 | View substance registered dossier |
Archroma Italy, S.r.l. - OR | Via Manzoni 37 20030 Palazzolo Milanese Italy | Italy | Cease Manufacture | (Benzyloxycarbonyl)methyl 4-(1-Butyl-5-cyano-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo)-benzoate | 442-520-4 | - | 2017 | View substance registered dossier |
MINAKEM Beuvry Production SAS | 145, Chemin des Lilas 59310 Beuvry-la-Forêt France | France | Cease Manufacture | (Bromomethyl)cyclobutane | 700-027-4 | 17247-58-4 | 2015 | View substance registered dossier |
BASF Lampertheim GmbH | Chemiestrasse 22 68619 Lampertheim Germany | Germany | Cease Manufacture | (C12-C14)tert-alkylammonium methylphosphonate | 404-750-3 | 119415-07-5 | 2018 | View substance registered dossier |
- | - | - | - | (C14-C30-alkyl)phenyl-3-tolyliodonium trifluoromethansulfonate | 424-410-8 | - | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | (C14/C16/C18) n-alkyl (of non animal origin)benzyl dimethyl ammonium chloride compound with bentonite | 436-020-5 | - | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | (chloromethyl)bis(4-fluorophenyl)methylsilane | 401-200-4 | 85491-26-5 | - | View substance registered dossier |
MINAKEM Beuvry Production SAS | 145, Chemin des Lilas 59310 Beuvry-la-Forêt France | France | Active | (chloromethyl)cyclopropane | 227-632-1 | 5911-08-0 | - | View substance registered dossier |
Wacker Chemie AG | Hanns-Seidel-Platz 4 81737 Muenchen Germany | Germany | Active | (Chloromethyl)dimethoxymethylsilane | 606-938-2 | 2212-11-5 | 2008; 2011; 2022 | View substance registered dossier |
Wacker Chemie AG | Hanns-Seidel-Platz 4 81737 Muenchen Germany | Germany | Active | (Chloromethyl)methoxydimethylsilane | 700-268-5 | 18143-33-4 | 2008 | View substance registered dossier |
Wacker Chemie AG | Hanns-Seidel-Platz 4 81737 Muenchen Germany | Germany | Active | (Chloromethyl)trimethoxysilane | 611-813-0 | 5926-26-1 | 2008; 2011 | View substance registered dossier |
Excella GmbH & Co. KG | Nuernberger Str. 12 90537 Feucht Germany | Germany | Active | (cyclopropylmethoxy)acetic acid | 853-795-9 | 246869-08-9 | - | View substance registered dossier |
- | - | - | - | (D)-2-BROM-3-PHENYLPROPIONSÄURE-ETHYLENDIAMINSALZ | 447-890-0 | - | - | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Active | (E)-(6,10-dimethylundeca-1,5,9-trien-2-yl)cyclopropane | 834-085-8 | 714230-50-9 | - | View substance registered dossier |
Pliva Hrvatska doo | Prilaz baruna Filipovića 25 10000 Zagreb Croatia | Croatia | Active | (E)-2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-ylmethylene)-5,6-dimethoxy-indan-1-one hydrochloride | 940-983-1 | - | - | View substance registered dossier |
Fermion Oy | Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland | Finland | Active | (E)-2-(2-(4-dibenzo[b,f][1,4]thiazepin-11-yl)piperazin- 1-yl)ethoxy)ethanol hydrochloride | 696-107-0 | 930086-71-8 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (E)-3,7-dimethyl-2,6-octadienylhexadecanoate | 421-370-3 | 3681-73-0 | - | View substance registered dossier |
BASF Schwarzheide GmbH | Schipkauer Str. 1 01987 Schwarzheide Brandenburg Germany | Germany | Cease Manufacture | (E)-3-(2-chlorophenyl)-2-(4-fluorophenyl)propenal | 410-980-5 | 112704-51-5 | 2018 | View substance registered dossier |
- | - | - | - | (E)-3-(3-Pent-1-yloxiran-2-yl)prop-2-enal | 443-070-1 | 188590-62-7 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | No longer Valid | (E)-3-(4-(4-fluorophenyl)-5-methoxymethyl-2,6-bis(1-methoxymethyl)pyridin-3-yl)prop-2-enal | 426-330-9 | 177964-68-0 | 2022 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. | - | - | Active | (E)-3-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol | 428-010-4 | 82413-20-5 | - | View substance registered dossier |
Sterling Pharma Solutions Ltd | Dudley NE23 7QG Cramlington Northumberland United Kingdom | United Kingdom | No longer Valid | (E)-3-[6-(p-toluoyl)-2-pyridyl]acrylic acid | 302-128-5 | 94094-27-6 | 2021 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (E)-3-methyl-5-cyclopentadecen-1-one | 429-900-5 | 82356-51-2 | - | View substance registered dossier |
Solvay Fluor GmbH | Hans-Boeckler-Allee 20 30173 HANNOVER Germany | Germany | Active | (E)-4-Ethoxy-1,1,1-trifluoro-3-buten-2-one (stabilized with BHT) | 475-900-3 | - | 2010; 2014; 2019 | View substance registered dossier |
Bayer AG | Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany | Germany | Cease Manufacture | (E)-5-benzyl-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-N-nitro-1,3,5-triazinan-2-imine | 606-753-7 | 213967-55-6 | 2023 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. | - | - | Active | (E)-Ethyl 4-oxo-but-2-enoate | 438-470-8 | - | - | View substance registered dossier |
FINORGA SAS | 497 route de Givors 38670 CHASSE SUR RHONE France | France | Active | (E)-N-((dialkylamino)alkylene)-3,5-bis(polyfluoroalkyl)benzamide | - | - | 2016 | View substance registered dossier |
Symrise AG | Mühlenfeldstraße 1 37603 Holzminden Germany | Germany | Active | (E)-non-3-en-2-one | 813-141-5 | 18402-83-0 | - | View substance registered dossier |
DSM Nutritional Products France SAS | 1 boulevard d'Alsace F-68128 Village-Neuf France | France | Active | (E,E)-3,7,11-Trimethyldodeca-1,4,6,10-tetraen-3-ol | 423-240-1 | 125474-34-2 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (E,Z)-4-chlorophenyl(cyclopropyl)ketone O-(4-nitrophenylmethyl)oxime | 406-100-4 | 94097-88-8 | - | View substance registered dossier |
PCAS | 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France | France | Active | (E-E )-3,3'-(1,4-phenylenedimethylidene)bis(2-oxobornane-10-sulfonic acid) | 410-960-6 | 92761-26-7 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (ethyl-3-oxobutanoato-O'1,O'3)(2-dimethylaminoethanolato)(1-methoxypropan-2-olato)aluminium(III), dimerised | 402-370-2 | 149057-70-5 | - | View substance registered dossier |
Nouryon Surface Chemistry AB | Box 47067 40258 Göteborg Sweden | Sweden | Active | (hydroxyethyl)urea | 215-304-0 | 1320-51-0 | 2013; 2021 | View substance registered dossier |
- | - | - | - | (imidazol-5-yl)ethyl-3-aminopropionamide dihydrochloride | 415-470-6 | - | - | View substance registered dossier |
Wacker Chemie AG | Hanns-Seidel-Platz 4 81737 Muenchen Germany | Germany | Active | (Isocyanatomethyl)(dimethoxy)methylsilane | 453-230-2 | 406679-89-8 | 2011; 2021 | View substance registered dossier |
CARBOGEN AMCIS B.V. | Nieuweweg 2a 3901 BE Veenendaal Netherlands | Netherlands | Active | (methoxymethyl)triphenylphosphonium chloride | 223-664-5 | 4009-98-7 | - | View substance registered dossier |
[Confidential] | - | - | - | (N-(1,1-Dimethylethyl)-1,1-dimethyl-1-((1,2,3,4,5-eta)-2,3,4,5-tetramethyl-2,4-cyclopentadien-1-yl)silanaminato(2-)-kappan)((1,2,3,4-eta)-1,3-pentadiene)-titanium | 419-840-8 | 169104-71-6 | - | View substance registered dossier |
Alzchem Trostberg GmbH | Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany | Germany | Active | (N-phenylcarbamimidoyl)ammonium carbonate hydrate | 485-350-6 | - | 2009; 2019 | View substance registered dossier |
[Confidential] | - | - | - | (N-phenylcarbamimidoyl)ammonium carbonate hydrate | 485-350-6 | - | - | View substance registered dossier |
Siegfried St. Vulbas SAS | 530, allée de la Luye 01150 SAINT VULBAS France | France | Active | (p-chlorophenyl)metaboric acid | 216-845-5 | 1679-18-1 | - | View substance registered dossier |
ICL Europe Coöperatief U.A. (OR1) | Koningin Wilhelminaplein 30 Prinsenhof 1062 KR Amsterdam Netherlands | Netherlands | Active | (pentabromophenyl)methyl acrylate | 261-767-7 | 59447-55-1 | - | View substance registered dossier |
PIERRE FABRE MEDICAMENT | Les Cauquillous 81500 LAVAUR France | France | Active | (pyridin-3-yl)methanol hydrofluoride | 700-352-1 | 62756-44-9 | - | View substance registered dossier |
BASF SE | Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany | Germany | Active | (R)-(-)-1-methoxy-2-propylamine | 620-037-1 | 99636-38-1 | 2010 | View substance registered dossier |
ROLABO OUTSOURCING, S.L. | Polígono Industrial Malpica. Calle J, nº 3-4 50016 Zaragoza Zaragoza Spain | Spain | Active | (R)-(−)-2-hydroxy-4-phenylbutyric acid ethyl esther | 618-525-4 | 90315-82-5 | - | View substance registered dossier |
RECORDATI SPA | Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy | Italy | Active | (R)-1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline, compound with (S)-2-(6-methoxy-naphthalen-2-yl)-propionic acid | 941-846-9 | - | - | View substance registered dossier |
Siegfried PharmaChemikalien Minden GmbH | Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany | Germany | Active | (R)-1-hydroxy-1-phenylacetone | 217-285-4 | 1798-60-3 | 2013 | View substance registered dossier |
Bayer AG | Kaiser-Wilhelm-Allee 51373 Leverkusen Germany | Germany | Active | (R)-2-(2,5-difluorophenyl)pyrrolidine (R)-2-hydroxysuccinate | 845-727-1 | 1919868-77-1 | 2022 | View substance registered dossier |
NuFarm Limited | Wyke Lane BD12 9EJ Wyke West Yorkshire United Kingdom | United Kingdom | No longer Valid | (R)-2-(4-hydroxyphenoxy)propanoic acid | 407-960-3 | 94050-90-5 | 2021 | View substance registered dossier |
- | - | - | - | (R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propionic acid | 440-090-2 | 86123-10-6 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (R)-2-acetamido-3-naphthyl-2-yl-propionic acid | 440-450-9 | - | - | View substance registered dossier |
cordenpharma chenove | 47, rue de Longvic 21300 Chenôve France | France | Active | (R)-2-Benzylamino-1-((S)-6-fluoro-chroman-2-yl)-ethanol | 600-381-9 | 1030385-16-0 | - | View substance registered dossier |
- | - | - | - | (R)-2-bromo-3-methylbutyric acid diisopropylamine salt | 448-650-8 | 169320-29-0 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (R)-2-tert-butoxycarbonylamino-3-(4-chlorophenyl)propionic acid | 438-070-3 | - | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (R)-2-tert-butoxycarbonylamino-3-(pyridin-3-yl)propionic acid | 441-200-1 | - | - | View substance registered dossier |
Amino Chemicals Ltd | Industrial Estate, A61 MRS3000 Marsa Malta | Malta | Active | (R)-2-{[(3-methyl-4-nitropyridine-2-yl)methyl]sulfinyl}-1H-benzimidazole | 700-683-1 | 853950-77-3 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)ethenyl)-1H-indole | 430-560-5 | 180637-89-2 | - | View substance registered dossier |
Pfizer Ireland Pharmaceuticals | n/a P43 X336 Ringaskiddy Cork Ireland | Ireland | Active | (R)-3-(2-benzyloxy)-5-bromophenyl)-N,N-diisopropyl-3-phenylpropan-1-amine | 700-662-7 | 950773-38-3 | - | View substance registered dossier |
COVANCE CLINICAL DEVELOPMENT SA 171 | Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain | Spain | Cease Manufacture | (R)-3-chloropropane-1,2-diol | 435-560-9 | 57090-45-6 | 2012 | View substance registered dossier |
Lundbeck Pharmaceuticals Italy S.p.A | via quarta strada 2 35129 padova Italy | Italy | Active | (R)-4-(4-dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemi (2R, 3R)-2,3-bis((4-methylbenzoyl)oxy)succinoate | 949-784-4 | - | - | View substance registered dossier |
- | - | - | - | (R)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide | 419-800-1 | - | - | View substance registered dossier |
Pliva Hrvatska doo | Prilaz baruna Filipovića 25 10000 Zagreb Croatia | Croatia | Active | (R)-5-(Azidomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxazolidinone | 801-918-1 | 168828-84-0 | - | View substance registered dossier |
ORGAPHARM | Rue du Moulin de la Canne 45300 PITHIVIERS France | France | Active | (R)-5-bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole | 422-390-5 | 143322-57-0 | - | View substance registered dossier |
Pfizer Ireland Pharmaceuticals | n/a P43 X336 Ringaskiddy Cork Ireland | Ireland | No longer Valid | (R)-5-bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole | 422-390-5 | 143322-57-0 | 2013 | View substance registered dossier |
TAKASAGO TICSA-Producer/Importer | Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain | Spain | Active | (R)-6-(isopropyl)-3-methylcyclohex-2-en-1-one | 224-957-0 | 4573-50-6 | - | View substance registered dossier |
Clarochem Ireland Ltd | damastown mulhuddart dn 15 dublin Ireland | Ireland | Active | (R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate | 418-570-8 | 25383-07-7 | 2016 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. | - | - | Active | (R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate | 418-570-8 | 25383-07-7 | - | View substance registered dossier |
Excella GmbH & Co. KG | Nuernberger Str. 12 90537 Feucht Germany | Germany | Active | (R*,S*)-(±)-α-[4-[2-(dimethylamino)ethoxy]phenyl]-β-ethyl-α-phenylphenethyl alcohol | 278-718-0 | 77542-06-4 | - | View substance registered dossier |
Pfizer Ireland Pharmaceuticals | n/a P43 X336 Ringaskiddy Cork Ireland | Ireland | Active | (R, S)-1-[2-amino-1(4-methoxyphenyl)ethyl]cyclohexanol acetate | 445-750-3 | 839705-03-2 | 2013 | View substance registered dossier |
Minakem Dunkerque Production | 224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France | France | Active | (R,E)-N-[1-(5-bromo-2-fluorophenyl)ethylidene]-2-methylpropane-2-sulfinamide | 810-396-4 | 1194044-26-2 | 2017 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. | - | - | Active | (R,S)-2-Amino-3,3-dimethylbutane amide | 447-860-7 | 144177-62-8 | - | View substance registered dossier |
SP QUIMICA SA | Crta. Reus a Riudoms Km. 4, 1 43330 RIUDOMS TARRAGONA Spain | Spain | Active | (R,S)-2-amino-3-hydroxy-N'-[(E)-(2,3,4-trihydroxyphenyl)methylidene]propanehydrazide hydrochloride (1:1) | 940-411-0 | 1353749-74-2 | - | View substance registered dossier |
Vishay BCcomponents B.V. | Ceintuurbaan 15 8022 AW Zwolle Netherlands | Netherlands | Active | (R,S)-2-butyloctanedioic acid | 431-210-4 | 50905-10-7 | - | View substance registered dossier |
PCAS | 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France | France | Active | (R,S)-N-acetyl-(3,4-dimethoxyphenyl)-alanine, monohydrate | 608-083-0 | 27313-65-1 | - | View substance registered dossier |
Plixxent B.V. | Korte Groningerweg 1A 9607 Foxhol Netherlands | Netherlands | Active | (Reaction product of 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol, 2-(2-hydroxyethylamino)ethanol and formaldehyde), propoxylated | 926-000-9 | - | 2013; 2016; 2017; 2018; 2021; 2022 | View substance registered dossier |
Syngenta Ltd | Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom | United Kingdom | No longer Valid | (RS)-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)hexan-2-ol | 413-050-7 | 79983-71-4 | 2021 | View substance registered dossier |
Bayer Agriculture bvba | Scheldelaan 460 B-2040 Antwerp Belgium | Belgium | Cease Manufacture | (RS)-3-dichloroacetyl-5-(2-furanyl)-2,2-dimethyloxazolidine | 434-800-1 | - | 2020 | View substance registered dossier |
- | - | - | - | (S) 4-hydroxy-3-methyl-2-prop-2-ynylcyclopent-2-en-1-one | 462-540-7 | 77087-34-4 | - | View substance registered dossier |
BASF SE | Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany | Germany | Active | (S)-(+)-1-methoxy-2-propylamine | 700-220-3 | 99636-32-5 | 2010 | View substance registered dossier |
Janssen Pharmaceutica N.V. | Turnhoutseweg 30 2340 Beerse Belgium | Belgium | Cease Manufacture | (S)-(+)-2-(2-Chlorophenyl)-2-hydroxyacetic acid | 700-307-6 | 52950-19-3 | 2019 | View substance registered dossier |
Carbogen Amcis Ltd | 303 Clayton Lane M11 4SX Manchester Greater Manchester United Kingdom | United Kingdom | No longer Valid | (S)-(-)-tetrahydro-2-furoic acid | 433-770-5 | - | 2021 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (S)-(-)-tetrahydro-2-furoic acid | 433-770-5 | - | - | View substance registered dossier |
Reuter Chemische Apparatebau e.K. | Engesserstrasse 4b 79108 Freiburg Germany | Germany | Active | (S)-1,1'-Binaphthalene-2,2'-diol | 606-050-5 | 18531-99-2 | 2011; 2013 | View substance registered dossier |
UnaveraChemLab | Am Ländbach 20 82481 Mittenwald Germany | Germany | Active | (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol | 700-699-9 | 877397-65-4 | - | View substance registered dossier |
BASF SE | Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany | Germany | Active | (S)-1-(p-tolyl)ethanamine | 623-635-0 | 27298-98-2 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. | - | - | Active | (S)-1-[2-tert-butoxycarbonyl-3-(2-methoxyethoxy)propyl]-1-cyclopentanecarboxylic acid, cyclohexylamine salt | 425-510-4 | 167944-94-7 | - | View substance registered dossier |
DSM Pharma Chemicals Venlo B.V. | Grubbenvorsterweg 8 Postbox 81 5900 AB Venlo Netherlands | Netherlands | Active | (S)-2,3-dihydro-1H-indole-2-carboxylic acid | 410-860-2 | 79815-20-6 | - | View substance registered dossier |
[Confidential] | - | - | - | (S)-2-((tert-Butoxycarbonyl)amino)-3,3-dimethylbutanoic acid | 613-118-8 | 62965-35-9 | - | View substance registered dossier |
Cambrex Karlskoga AB | Bjorkborns Industriomrade 69185 Karlskoga Sweden | Sweden | Cease Manufacture | (S)-2-(1-aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one hydrochloride | 942-180-1 | - | 2017 | View substance registered dossier |
Flamma S.p.a. | via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy | Italy | Active | (S)-2-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid | 951-381-3 | - | 2021 | View substance registered dossier |
Sterling Pharma Solutions Ltd | Dudley NE23 7QG Cramlington Northumberland United Kingdom | United Kingdom | No longer Valid | (S)-2-(5-Oxo-3-propyl-1,2-dihydropyrrol-1-yl) butyramide | 824-341-7 | 357338-13-7 | 2021 | View substance registered dossier |
Flamma S.p.a. | via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy | Italy | Active | (S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid | 439-640-4 | - | 2019; 2020; 2022 | View substance registered dossier |
QUIMICA SINTETICA, S.A. | C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain | Spain | Active | (S)-2-amino-1,1-diphenyl 1-propanol | 622-109-8 | 78603-91-5 | - | View substance registered dossier |
Boehringer Ingelheim Pharma GmbH & Co. KG | Binger Strasse 173 55216 Ingelheim am Rhein Germany | Germany | Cease Manufacture | (S)-2-Amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole | 600-593-1 | 104632-26-0 | 2019 | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Active | (S)-2-chloro-1-(3,4-difluorophenyl)ethan-1-ol | 819-945-2 | 1006376-60-8 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | (S)-2-chloropropionic acid | 411-150-5 | 29617-66-1 | - | View substance registered dossier |
TÜV SÜD Industrie Service GmbH | Westendstr. 199 IS-CMS-MUC 80686 Munich Germany | Germany | Cease Manufacture | (S)-2-Hydroxy-3,3-dimethyl-4-butanolide | 626-470-2 | 5405-40-3 | 2015 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | No longer Valid | (S)-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid | 431-910-1 | - | 2022 | View substance registered dossier |
Esteve Quimica, S.A. | Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain | Spain | Cease Manufacture | (S)-3-benzyloxycarbonyl-1,2,3,4-tetrahydro-isoquinolinium 4-methylbenzenesulfonate | 406-960-0 | 77497-97-3 | 2017 | View substance registered dossier |
Boehringer Ingelheim Pharma GmbH & Co. KG | Binger Strasse 173 55216 Ingelheim am Rhein Germany | Germany | Cease Manufacture | (S)-3-Methyl-1-(2-piperidine-1-phenyl)butylamine compound with N-Acetyl-L-glutamic acid | 606-883-4 | 219921-94-5 | 2023 | View substance registered dossier |
Boehringer Ingelheim Pharma GmbH & Co. KG | Binger Strasse 173 55216 Ingelheim am Rhein Germany | Germany | Cease Manufacture | (S)-3-Methyl-1-(2-piperidinophenyl)-1-butylamine | 604-603-5 | 147769-93-5 | 2023 | View substance registered dossier |
Fermion Oy | Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland | Finland | Active | (S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile | 941-762-2 | 1297537-41-7 | - | View substance registered dossier |
H. Lundbeck A/S | Ottiliavej 7-9 2500 Copenhagen Denmark | Denmark | Active | (S)-4-(4-Dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile | 430-770-7 | 128173-52-4 | - | View substance registered dossier |
- | - | - | - | (S)-4-amino-5-[(2-(1H-imidazol-4-yl)ethyl)amino]-5-oxopentanoic acid | 421-900-3 | - | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority. | - | - | Active | (S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione | 444-280-6 | 7689-03-4 | - | View substance registered dossier |
Fermion Oy | Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland | Finland | Active | (S)-5-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-3-carboxamide | 941-760-1 | 1297537-33-7 | - | View substance registered dossier |
Patheon Austria GmbH & Co KG | St. Peterstrasse 25 A-4020 Linz Austria | Austria | Active | (S)-5-tert-butoxy-3-(tert-butyldimethylsilyloxy)-5-oxopentylboronic acid (+)-pinanediol ester | 811-219-3 | 1681053-95-1 | - | View substance registered dossier |
- | - | - | - | (S)-7-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one glucopyranosyl ether | 471-940-0 | - | - | View substance registered dossier |
In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).
ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.
As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).
In the portal results table are presented:
- Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
- Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
- Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
- Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
- Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
- Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
- Link to the full factsheet.
A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.
RELATED INFORMATION
- Registered substances information
- How to determine what will be published (Data Submission Manual 15)
- Understanding REACH Regulation
- Q&A on registered substances
- What is an Infocard? [PDF]
- What is a Registered substance Factsheet? [PDF]
- eChemPortal
- REACH study results download
- REACH Regulation
- ECHA Legal notice
Welcome to the REACH Registered Substance Factsheets
Here you will find details from REACH registrations submitted to ECHA. Registrations under REACH can be submitted either jointly – where a group of legal entities pool their data – or individually. The set of details from each published joint or individual submission is presented as a row in the results table. For each row there is also an ‘eye’ icon leading to the detailed factsheet which contains the entire public dataset, following the IUCLID format.
Note that there can be more than one joint or individual submission for the same substance, thus there can be cases where one substance is covered by many REACH registered substance factsheets.
Note too, that as mentioned in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission.
Finally, please note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).
All substances table
The “All substances” table gives an overview of all the REACH registered substance factsheets on file at ECHA. Since this covers all data ever submitted since the entry into force of the REACH Regulation, there are some substances which are no longer considered registered under REACH in the EU / EEA. These can be for example substances that were registered only in the UK; since Brexit they are no longer registered in the EU / EEA.
The following columns are presented in the “All substances” table:
- Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
- Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
- Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
- Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
- Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
- Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
- ‘Eye’ icon linking to the full factsheet.
Searching
The search for REACH registered substance factsheets is divided into logically separated blocks of related search filters. Note that the search works so that if you provide filters in different blocks, then the results returned must match the filters in block 1 AND those in block 2 etc. Searches are conducted on all the public data included in all published REACH registrations.
Substance identity
In this block you can search by substance identifiers, under filters for Name, EC / List number, and CAS number. Full or partial identifiers can be used. And under the Name filter you can search by any substance name of any kind from any source. Other numerical identifiers such as Harmonised C&L Index number, or PIC CN code can also optionally be used.
Administrative data
In this block you can search by administrative information relating to REACH registered substance factsheets:
- Registration type – picklist of Full, Intermediate, NONS
- Registration status – picklist of Active, Cease Manufacture, No longer valid
- Submission type – Individual or Joint
- Country in which registered – picklist of current and former EU / EEA member states from which REACH registrations were received
- First published date – the date when a REACH registration factsheet was first published
- Last update date – the last date when any registrant / supplier submission contributing to a given REACH registration factsheet was submitted
- Last update year – the year in which any registrant / supplier last made an update submission included in a given REACH registration factsheet
- Registrant / supplier name – where available and not claimed confidential
- Registration number – where available and not claimed confidential
- Registrant address – where available and not claimed confidential
Substance data
In this block you can search by substance related data from REACH registered substance factsheets:
- Tonnage band – picklist of Tonnage range, Tonnage Confidential, Intermediate use only
- Selected total tonnage band range – available only if Tonnage range is selected, and allows to filter REACH registered substance factsheets within any selected min and max value
- Substance has nanoform – picklist of Yes, No
- PBT assessment outcome – picklist of all possible PBT assessment outcomes
- CSA performed – picklist of Yes, No
Use and exposure
In this block you can search by elements relating to how use and exposure are encoded in REACH registrations.
Under the Life cycle option you can select one or more life cycle stages. The search results returned will include only factsheets containing uses reported under the selected life cycle stages.
Under the Category option there are modal popups for each of the use descriptor categories – Product, Sector of use, Process, Environmental release, and Article categories. In each of these are multi select picklists for all the related descriptor codes. The search results returned will include only factsheets containing uses which include the selected descriptor codes.
Note that the Life cycle and Category options work together, so that if a life cycle stage and Category options are both selected the search results will include factsheets containing specific uses in the selected life cycle stage, and where the use includes the selected descriptor codes.
With the search operator option you can select to refine how the search works. AND refines results and returns only those factsheets where ALL the search filter criteria are met. OR broadens the results and returns factsheets where ANY of the selected search filter criteria are met.
The factsheets
There is always a detailed factsheet per joint or individual submission, and it is generated based primarily on the IUCLID format.
The factsheet header begins with the identity of the substance in question, to which the factsheet is linked. The substance identity should always be aligned with that shown in the related substance Infocard. Note that since the Infocard refreshes daily, whereas the factsheet sometimes refreshes on a slower pace, sometimes the data may be out of alignment. In such cases it will always realign as quickly as possible.
The substance identification is enriched with the data provided in the relevant IUCLID section of the primary submitted dossier – either the joint submission lead, or the single individual submission.
In this section are also provided the type of substance, all other identifiers such as trade names, common names, other names etc, as well as all distinct submitted compositions for the substance.
Next is a page covering administrative type information from the data submitted, including:
Registration details, on the total tonnage band informed to ECHA, the registration type, first published and last updated dates, and whether a chemical safety assessment has been performed.
Registrant / supplier details, giving the identity and status of registrants / suppliers, except where the identity has been claimed confidential.
Registration numbers, giving again the identity and status of registration numbers, except where claimed confidential.
Contact persons responsible for the SDS, giving the non-confidential SDS contacts provided to ECHA.
The remainder of the factsheet faithfully follows the IUCLID structure, covering the C&L and PBT, Manufacture, use, and exposure, Physical and chemical properties, Environmental fate and pathways, Ecotoxicological information, Toxicological information, Analytical methods (if available), Guidance on safe use, Assessment reports, and Reference substances.