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Registered substances

Registered substances

The data comes from registration dossiers submitted to ECHA by the date indicated as last update. The Total Tonnage Band is compiled from all the dossiers with two exceptions; any tonnages claimed confidential and any quantity used as an intermediate to produce a different chemical. The Total Tonnage band published does not necessarily reflect the registered tonnage band(s).

Please note that some of the information on registered substances may belong to third parties. The use of such information may therefore require the prior permission of the third party owners. Please consult the Legal Notice for further information.

Please note that information on chemical properties of registered substances is directly accessible via eChemPortal

The result of the search ‘Substance has nanoform’ returns all factsheets containing data related to nanomaterials. However, this does not mean that a registration covering nanoforms of the substance has been submitted in line with the revised annexes of REACH by all the registrants concerned. Note that since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA using IUCLID version 6.4 (released on 30 October 2019).

Last updated 05 April 2020. Database contains 22764 unique substances and contains information from 99007 dossiers.
Substance identity
Administrative data
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Substance data
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Uses and exposure
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4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid
810-200-7 1050477-45-6 Intermediate Individual Intermediate Use Only View substance registered dossier
4-(4-fluorophenyl)-2-(2-methyl-1-oxopropyl)-4-oxo-3,N-diphenylbutanamide
425-850-3 125971-96-2 NONS Individual Tonnage Data Confidential View substance registered dossier
4-(4-hydroxyphenyl)cyclohexanone
423-920-8 - NONS Individual Tonnage Data Confidential View substance registered dossier
4-(4-iodo-1H-pyrazol-1-yl)piperidine
639-824-6 1229457-94-6 Intermediate Individual Intermediate Use Only View substance registered dossier
4-(4-isopropoxyphenylsulfonyl)phenol
405-520-5 95235-30-6 NONS Individual Tonnage Data Confidential View substance registered dossier
4-(4-methoxyphenyl)butan-2-one
203-184-2 104-20-1 Intermediate Individual Intermediate Use Only View substance registered dossier
4-(4-methoxyphenyl)cyclohexanone
610-959-2 5309-16-0 Intermediate Individual Intermediate Use Only View substance registered dossier
4-(4-Methylpiperazin-1-yl)-2-[(tetrahydropyran-4-yl)(2,2,2-trifluoroacetyl)amino]benzoic acid tert-butyl ester
840-712-6 1034975-53-5 Intermediate Individual Intermediate Use Only View substance registered dossier
4-(4-nitrophenyl)sulfonylaniline
606-323-9 1948-92-1 Intermediate Individual Intermediate Use Only View substance registered dossier
4-(4-nitrophenylazo)-2,6-di-sec-butyl-phenol
410-610-2 111850-24-9 NONS Individual Tonnage Data Confidential View substance registered dossier
4-(4-tolyloxy)biphenyl
405-730-7 51601-57-1 NONS Individual Tonnage Data Confidential View substance registered dossier
4-(4-trans-vinyl-[1,1'-bicyclohexyl]-4'-trans-yl)-1,2-difluorobenzene
430-860-6 - NONS Individual Tonnage Data Confidential View substance registered dossier
4-(5-(5-[1-(4-carboxyphenyl)hexahydro-2,4,6-trioxopyrimidin-5-ylidene]penta-1,3-dienyl)-1,2,3,4-tetrahydro-6-hydroxy-2,4-dioxopyrimidin-1-yl)benzoic acid-triethylamine salt
426-900-7 - NONS Individual Tonnage Data Confidential View substance registered dossier
4-(5-ethoxyheptyl)perhydropentalen-2-one
419-880-6 - NONS Individual Tonnage Data Confidential View substance registered dossier
4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide
448-010-8 - NONS Individual Tonnage Data Confidential View substance registered dossier
4-(5-thioxo-2,5-dihydro-1H-tetrazol-1-yl)benzoic acid
680-188-4 23249-95-8 Intermediate Individual Intermediate Use Only View substance registered dossier
4-(6-(3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile bis sulphate
951-814-6 - Intermediate Individual Intermediate Use Only View substance registered dossier
4-(6-acryloyloxyhexyloxy)-benzoic acid (4-cyanophenyl ester)
425-120-4 83847-14-7 NONS Individual Tonnage Data Confidential View substance registered dossier
4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester)
425-880-7 - NONS Individual Tonnage Data Confidential View substance registered dossier
4-(6-hydrazinopyrimidin-4-yl)morpholine
691-196-2 5767-36-2 Intermediate Individual Intermediate Use Only View substance registered dossier
4-(benzylamino)-5-methyl-2(1H)-pyridinon
809-933-5 95306-62-0 Intermediate Individual Intermediate Use Only View substance registered dossier
4-(bromoacetyl)benzonitrile
606-435-8 20099-89-2 Intermediate Individual Intermediate Use Only View substance registered dossier
4-(butoxymethyl)-2-methoxyphenol
444-010-7 82654-98-6 Full Individual 0 - 10 tonnes per annum View substance registered dossier
4-(butoxymethyl)-2-methoxyphenol
444-010-7 82654-98-6 NONS Individual Tonnage Data Confidential View substance registered dossier
4-(chloromethyl)benzoyl chloride
212-881-0 876-08-4 Intermediate Individual Intermediate Use Only View substance registered dossier
4-(cyclohex-1-en-1-yl)-3-methylbutan-1-ol
806-826-5 1359994-45-8 Full Individual 1 - 10 tonnes per annum View substance registered dossier
4-(cyclohexylcarbonoimidoyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol
940-185-3 32860-09-6 Intermediate Individual Intermediate Use Only View substance registered dossier
4-(diethylamino)-2-butyn-1-ol
234-163-6 10575-25-4 Intermediate Individual Intermediate Use Only View substance registered dossier
4-(dimethylamino)-3-methylbutan-2-one
244-782-3 22104-62-7 Intermediate Individual Intermediate Use Only View substance registered dossier
4-(ethoxycarbonyl)-1,3-thiazolidin-3-ium chloride
613-908-2 66223-38-9 Intermediate Individual Intermediate Use Only View substance registered dossier
4-(methylsulfonyl)-2-(trifluoromethyl)benzaldehyde
812-681-9 1215310-75-0 Intermediate Individual Intermediate Use Only View substance registered dossier
4-(N,N-dibutylamino)-2-hydroxy-2'-carboxybenzophenone
410-410-5 54574-82-2 NONS Individual Tonnage Data Confidential View substance registered dossier
4-(p-chlorophenyl)piperidin-4-ol
254-479-8 39512-49-7 Intermediate Individual Intermediate Use Only View substance registered dossier
4-(Pyridin-4-yl)-1,3-thiazole-2(3H)-thione
616-441-2 77168-63-9 Intermediate Individual Intermediate Use Only View substance registered dossier
4-(trans-4-propylcyclohexyl)phenyl acetic acid
435-100-7 - NONS Individual Tonnage Data Confidential View substance registered dossier
4-({[4-(acryloyloxy)butoxy]carbonyl}oxy)benzoic acid
608-403-9 297132-04-8 Intermediate Individual Intermediate Use Only View substance registered dossier
4-4'-methylenebis(oxyethylenethio)diphenol
407-480-4 93589-69-6 NONS Individual Tonnage Data Confidential View substance registered dossier
4-[(1E)-(hydroxyimino)methyl]-2-methoxyphenol
700-807-4 134283-49-1 Intermediate Individual Intermediate Use Only View substance registered dossier
4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile
700-455-1 380843-75-4 Full Individual 0 - 10 tonnes per annum View substance registered dossier
4-[(2-methoxybenzoyl)sulfamoyl]benzoyl chloride
617-251-2 816431-72-8 Intermediate Individual Intermediate Use Only View substance registered dossier
4-[(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)thio]butane-1-thiol
811-734-3 36097-07-1 Full Individual 0 - 10 tonnes per annum View substance registered dossier
4-[(3-chlorophenyl)(1H-imidazol-1-yl)methyl]-1,2-benzenediamine dihydrochloride
425-030-5 159939-85-2 Intermediate Individual Intermediate Use Only View substance registered dossier
4-[(3-hydroxypropyl)amino]-3-nitrophenol
406-305-9 92952-81-3 NONS Individual Tonnage Data Confidential View substance registered dossier
4-[(3-isobutoxy-1-isobutoxycarbonyl-3-oxopropyl)(3-octyloxypropyl)amino]-4-oxobutyric acid; reaction mass of: 4-[(3-decyloxypropyl)(3-isobutoxy-1-isobutoxycarbonyl-3-oxopropyl)amino]-4-oxobutyric acid
423-750-4 - NONS Individual Tonnage Data Confidential View substance registered dossier
4-[(3-methylphenyl)amino]pyridine-3-sulfonamide
615-805-8 72811-73-5 Intermediate Individual Intermediate Use Only View substance registered dossier
4-[(4,6-bis{[3-(diethylamino)propyl]amino}-heteromonocycle-2-yl)amino]-N-[2-(4,5,6,7-tetrachloro-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)quinolin-8-yl]benzenesulfonamide
- - Full Individual 0 - 10 tonnes per annum View substance registered dossier
4-[(4-(aminoiminomethyl)phenyl)amino]-4-oxobutanoic acid hydrochloride
430-340-9 - NONS Individual Tonnage Data Confidential View substance registered dossier
4-[(4-chloro-6-{[(3 or 4)-sulfophenyl]amino}-1,3,5-triazin-2-yl)amino]-2-{[1-ethyl-2-hydroxy-4-methyl-6-oxo-5-(sulfonatomethyl)-1,6-dihydropyridin-3-yl]diazenyl}benzenesulfonic acid, lithium sodium salts
942-795-5 - Full Individual 10 - 100 tonnes per annum View substance registered dossier
4-[(4-Fluorophenylimino)methyl]phenol
438-950-7 - NONS Individual Tonnage Data Confidential View substance registered dossier
4-[(4-methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride
600-728-4 106261-49-8 Intermediate Individual Intermediate Use Only View substance registered dossier
4-[({(3R,3aR,6S,6aR)-6-[(4-{[4-({[4-(acryloyloxy)butoxy]carbonyl}oxy)benzoyl]oxy}benzoyl)oxy]hexahydrofuro[3,2-b]furan-3-yl}oxy)carbonyl]phenyl 4-({[4-(acryloyloxy)butoxy]carbonyl}oxy)benzoate
431-360-0 - NONS Individual Tonnage Data Confidential View substance registered dossier
4-[2-((6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-ylsulfanyl)thiazole-4-yl]-1-methyl-pyridiniumchloride monohydrochloride
447-990-4 - NONS Individual Tonnage Data Confidential View substance registered dossier
4-[2-(1-methyl-2-(4-morpholinyl)ethoxy)ethyl]morpholine
407-940-4 111681-72-2 NONS Individual Tonnage Data Confidential View substance registered dossier
4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid
429-790-9 137281-39-1 Intermediate Individual Intermediate Use Only View substance registered dossier
4-[2-(Cyclopropylmethoxy)ethyl]phenol
440-910-9 - NONS Individual Tonnage Data Confidential View substance registered dossier
4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol
700-516-2 93413-62-8 Intermediate Individual Intermediate Use Only View substance registered dossier
4-[2-[(phenylmethyl)amino]propyl]- Phenol
608-112-7 27566-05-8 Intermediate Individual Intermediate Use Only View substance registered dossier
4-[2-[4-(1,1-dimethylethyl)phenyl]ethoxy]quinazoline
410-580-0 120928-09-8 NONS Individual Tonnage Data Confidential View substance registered dossier
4-[2-Ethoxy-5-(4-methyl-1-piperazinylsulfonyl)benzamido]-1-3-propyl-1H-pyrazole-5-carboxamide
639-263-7 200575-15-1 Intermediate Individual Intermediate Use Only View substance registered dossier
4-[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionyloxy]-1-[2-[3-(3,5-di-tert-butyl-4-hydrophenyl)propionyloxy]ethyl]-2,2,6,6-tetramethylpiperidine
416-770-1 73754-27-5 Full Individual 0 - 10 tonnes per annum View substance registered dossier
4-[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionyloxy]-1-[2-[3-(3,5-di-tert-butyl-4-hydrophenyl)propionyloxy]ethyl]-2,2,6,6-tetramethylpiperidine
416-770-1 73754-27-5 NONS Individual Tonnage Data Confidential View substance registered dossier
4-[3-(diethoxymethylsilylpropoxy)-2,2,6,6-tetramethyl]piperidine
411-400-3 102089-33-8 NONS Individual Tonnage Data Confidential View substance registered dossier
4-[4-(1,3-dihydroxyprop-2-yl)phenylamino]-1,8-dihydroxy-5-nitroanthraquinone
406-057-1 114565-66-1 NONS Individual Tonnage Data Confidential View substance registered dossier
4-[4-(2-ethylhexyloxy)phenyl](1,4-thiazinane-1,1-dioxide)
418-320-8 133467-41-1 NONS Individual Tonnage Data Confidential View substance registered dossier
4-[4-(4-aminophenyl)piperazin-1-yl]phenol
616-147-4 74853-08-0 Intermediate Individual Intermediate Use Only View substance registered dossier
4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide hydrochloride
692-722-3 835621-07-3 Intermediate Individual Intermediate Use Only View substance registered dossier
4-[4-amino-5-hydroxy-3-(4-(2-sulfoxyethylsulfonyl)phenylazo)-2,7-disulfonapht-6-ylazo]-6-[3-(4-amino-5-hydroxy-3-(4-(2-sulfoxyethylsulfonyl)phenylazo)-2,7-disulfonapht-6-ylazo]phenylcarbonylamino]benzenesulfonic acid, x sodium salt
417-640-5 161935-19-9 NONS Individual Tonnage Data Confidential View substance registered dossier
4-[bis(2-tert-butyl-4-hydroxy-6-methylphenyl)methyl]phenyl 6-diazo-5-oxo-5,6-dihydronaphthalene-1-sulfonate
451-040-4 - NONS Individual Tonnage Data Confidential View substance registered dossier
4-acetyl-1-methylpyridinium 4-methylbenzenesulfonate
700-195-9 223398-24-1 Full Individual 0 - 10 tonnes per annum View substance registered dossier
4-acetyloxy-5β,20-epoxy-1,2α,4,7β,10β,13α-hexahydroxy-9-oxotax-11-en-2-yl benzoate
418-680-6 - NONS Individual Tonnage Data Confidential View substance registered dossier
4-amino-10-methyl folic acid ethylester hydroiodide
617-385-1 82784-24-5 Intermediate Individual Intermediate Use Only View substance registered dossier
4-amino-2,4-dihydro-5-(1-methylethyl)-3H-1,2,4-triazol-3-one
689-404-1 96240-10-7 Intermediate Individual Intermediate Use Only View substance registered dossier
4-amino-2,5-dichloro-N,N-dimethylbenzenesulphonamide
247-501-2 26175-68-8 Intermediate Individual Intermediate Use Only View substance registered dossier
4-amino-2-(aminomethyl)phenol dihydrochloride
412-510-4 135043-64-0 NONS Individual Tonnage Data Confidential View substance registered dossier
4-amino-2-(trifluoromethyl)benzonitrile
700-293-1 654-70-6 Intermediate Individual Intermediate Use Only View substance registered dossier
4-amino-2-(trifluoromethyl)benzonitrile
700-293-1 654-70-6 Intermediate Individual Intermediate Use Only View substance registered dossier
4-amino-2-(trifluoromethyl)benzonitrile
700-293-1 654-70-6 Intermediate Individual Intermediate Use Only View substance registered dossier
4-amino-3-[[4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]-1-naphthalene sulfonic acid
427-680-5 188907-52-0 NONS Individual Tonnage Data Confidential View substance registered dossier
4-amino-3-fluorophenol
402-230-0 399-95-1 Intermediate Individual Intermediate Use Only View substance registered dossier
4-amino-3-fluorophenol
402-230-0 399-95-1 NONS Individual Tonnage Data Confidential View substance registered dossier
4-Amino-3-methyl-4-(2-hydroxyethyl)amino-6-nitrobenzene
417-600-7 82576-75-8 NONS Individual Tonnage Data Confidential View substance registered dossier
4-Amino-5-chloro-2,1,3-benzothiodiazole
457-490-8 - Intermediate Individual Intermediate Use Only View substance registered dossier
4-amino-5-ethyl-1-(2-methoxyethyl)-1H-Pyrazole-3-carboxamide
438-910-9 - NONS Individual Tonnage Data Confidential View substance registered dossier
4-amino-5-hydroxy-6-(5-{4-chloro-6-[4-(2-sulfonatooxyethanesulfonyl)phenylamino]-1,3,5-triazin-2-ylamino}-2-sulfonatophenylazo)-3-(2-sulfonato-4-(2-sulfonatooxyethanesulfonyl)phenylazo)naphthalene-2,7-disulfonate potassium/sodium; reaction mass of: 4-amino-3-(4-ethenesulfonyl-2-sulfonatophenylazo)-5-hydroxy-6-(5-{4-chloro-6-[4-(2-sulfonatooxyethanesulfonyl)phenylamino]-1,3,5-triazin-2-ylamino}-2-sulfonatophenylazo)naphthalene-2,7-disulfonate potassium/sodium
451-440-9 586372-44-3 Full Individual 10+ tonnes per annum View substance registered dossier
4-amino-6-((E)-(4-(4-(ethenylsulfonyl)butanoyl)amino)-diazenyl)-3-((E)-4- (ethenylsulfonyl)-diazenyl)-5-hydroxypolycarbocyclo, polysulfonate, polyphenyl, sodium salt
401-000-7 - NONS Individual Tonnage Data Confidential View substance registered dossier
4-amino-6-chlorobenzene-1,3-disulphonamide
204-463-1 121-30-2 Intermediate Individual Intermediate Use Only View substance registered dossier
4-amino-6-chlorotoluene-3-sulphonic acid
201-837-6 88-51-7 Intermediate Individual Intermediate Use Only View substance registered dossier
4-amino-6-chlorotoluene-3-sulphonic acid
201-837-6 88-51-7 Intermediate Individual Intermediate Use Only View substance registered dossier
4-amino-N,N-diethylaniline
202-214-1 93-05-0 Intermediate Individual Intermediate Use Only View substance registered dossier
4-amino-N-(2-ethylhexyl)benzenesulphonamide
258-799-9 53817-09-7 Intermediate Individual Intermediate Use Only View substance registered dossier
4-amino-N-(2-methylquinolin-8-yl)benzenesulfonamide
700-562-3 909782-32-7 Intermediate Individual Intermediate Use Only View substance registered dossier
4-amino-N-[3-(diethylamino)propyl]benzamide
700-444-1 106595-73-7 Intermediate Individual Intermediate Use Only View substance registered dossier
4-aminoazobenzene
200-453-6 60-09-3 Intermediate Individual Intermediate Use Only View substance registered dossier
4-aminobenzoic acid
205-753-0 150-13-0 Intermediate Individual Intermediate Use Only View substance registered dossier
4-aminophenol
204-616-2 123-30-8 Intermediate Individual Intermediate Use Only View substance registered dossier
4-aminophenol
204-616-2 123-30-8 Intermediate Individual Intermediate Use Only View substance registered dossier
4-anilino-2-methoxybenzenediazonium hexafluorophosphate(1-)
442-910-4 68900-98-1 NONS Individual Tonnage Data Confidential View substance registered dossier
4-benzyl-1-(2-hydroxymethylphenyl)-2-phenylpiperazine-fumarate
700-842-5 1192015-20-5 Intermediate Individual Intermediate Use Only View substance registered dossier
4-benzyl-2,6-dihydroxy-4-aza-heptylene bis(2,2-dimethyloctanoate)
418-100-1 172964-15-7 NONS Individual Tonnage Data Confidential View substance registered dossier
4-benzyloxy-4'-(2,3-epoxy-2-methylprop-1-yloxy)diphenylsulfone
408-220-2 141420-50-0 NONS Individual Tonnage Data Confidential View substance registered dossier

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