Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
Link to the full factsheet.

Chemical Property Data Search

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:

The REACH Registered substance portal was updated on 9th November 2020; the REACH registered factsheets were further updated on 21st December 2020. Details of the improvements can be found at Dissemination Platform Updates. Reprocessing the entire dataset is ongoing since 21 December 2020. ECHA is making all possible efforts to make the improvements and additional data visible with the shortest delay.
The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.

Last updated 13 May 2021. Database contains 23207 unique substances and contains information from 102702 dossiers.

Substance identity

Substance name:

EC / List number:

CAS number:

Other Numerical Identifiers:

Administrative data

Registration type:

Registration status:

Submission type:

Individual

Joint

Country in which registered:

First published date:

Last update date:

Last update year:

Registrant / supplier name:

Registration number:

Registrant address:

Substance data

Tonnage band:

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Substance has nanoform:

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CSA performed:

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View all Registered Substances

Showing 24,151 - 24,200 of 25,859 results.

Name	EC / List no.	CAS no.	Registration Status	Registration type	Submission type	Total tonnage band	Last Updated	Details
tert-butyl (2-cyano-1H-pyrrol-1-yl)carbamate	810-524-9	937046-96-3	Cease Manufacture	Intermediate	Individual	Cease manufacture	24-08-2015	View substance registered dossier
tert-butyl (2-cyano-1H-pyrrol-1-yl)carbamate	810-524-9	937046-96-3	Active	Intermediate	Individual	Intermediate use only	26-03-2019	View substance registered dossier
tert-butyl (2S)-2-(3-fluoro-4-phenylphenyl)propanoate	945-962-0	-	Active	Intermediate	Joint	Intermediate use only	07-12-2017	View substance registered dossier
tert-butyl (2S)-2-(4-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate	813-157-2	1007882-59-8	Active	Intermediate	Individual	Intermediate use only	26-09-2016	View substance registered dossier
tert-butyl (2S)-2-[4-(4'-{2-[(2S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl]-1H-imidazol-5-yl}biphenyl-4-yl)-1H-imidazol-2-yl]pyrrolidine-1-carboxylate	941-432-8	-	Active	Intermediate	Individual	Intermediate use only	26-09-2014	View substance registered dossier
tert-butyl (2S)-2-carbamoyl-2,3-dihydropyrrole-1-carboxylate	615-204-0	709031-38-9	Active	Intermediate	Individual	Intermediate use only	21-03-2017	View substance registered dossier
tert-butyl (2S)-2-{4-[(6S)-10-{2-[(2S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl]-1H-imidazol-5-yl}-6-phenylindolo[1,2-c][1,3]benzoxazin-3-yl]-1H-imidazol-2-yl}pyrrolidine-1-carboxylate	813-165-6	1369595-05-0	Active	Intermediate	Individual	Intermediate use only	26-09-2016	View substance registered dossier
tert-butyl (2S,4S)-2-[4-(2-{(2S,5S)-1-[N-(methoxycarbonyl)-L-valyl]-5-methylpyrrolidin-2-yl}-1,11-dihydro[2]benzopyrano[4',3':6,7]naphtho[1,2-d]imidazol-9-yl)-1H-imidazol-2-yl]-4-(methoxymethyl)pyrrolidine-1-carboxylate	807-100-0	1378391-45-7	Active	Intermediate	Individual	Intermediate use only	28-09-2016	View substance registered dossier
tert-butyl (3-{[2-(1H-imidazol-4-yl)ethyl]amino}-3-oxopropyl)carbamate	813-660-7	143885-59-0	Active	Intermediate	Individual	Intermediate use only	19-12-2016	View substance registered dossier
tert-butyl (3R)-3-hydroxypyrrolidine-1-carboxylate	629-335-6	109431-87-0	Active	Intermediate	Joint	Intermediate use only	12-10-2020	View substance registered dossier
tert-butyl (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoate	609-144-4	355806-00-7	Active	Intermediate	Joint	Intermediate use only	13-03-2020	View substance registered dossier
tert-butyl (3S)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]pyrrolidine-1-carboxylate	861-843-5	1383793-75-6	Active	Intermediate	Joint	Intermediate use only	16-12-2020	View substance registered dossier
tert-butyl (3S,5S)-3-isopropyl-5-((2S,4S)-tetrahydro-4-isopropyl-5-oxo-furan-2-yl)-2-oxo-pyrrolidine-carboxylate	472-680-0	-	Active	Full	Joint	≥ 10 tonnes	26-02-2019	View substance registered dossier
tert-butyl (3S,6S)-3-((tert-butyldimethylsilyl)oxy)-6-chloro-6-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)hexanoate	811-363-7	1681053-96-2	Active	Intermediate	Joint	Intermediate use only	02-05-2018	View substance registered dossier
tert-butyl (4-bromo-2-cyano-1H-pyrrol-1-yl)carbamate	810-525-4	937047-04-6	Cease Manufacture	Intermediate	Individual	Cease manufacture	24-08-2015	View substance registered dossier
tert-butyl (4-bromo-2-cyano-1H-pyrrol-1-yl)carbamate	810-525-4	937047-04-6	Active	Intermediate	Individual	Intermediate use only	23-04-2019	View substance registered dossier
tert-butyl (4R)-cis-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate	425-780-3	125971-94-0	Active	Intermediate	Joint	Intermediate use only	16-03-2018	View substance registered dossier
tert-butyl (4R)-cis-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate	425-780-3	125971-94-0	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
tert-butyl (5S,6R,7R)-3-bromomethyl-5,8-dioxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	407-620-4	33610-13-8	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
tert-butyl (6S)-6-[4-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]heptane-5-carboxylate	939-899-8	1441670-89-8	Active	Intermediate	Joint	Intermediate use only	09-06-2015	View substance registered dossier
tert-butyl (6S)-6-[4-(7-{2-[(1R,3S,4S)-2-(tert-butoxycarbonyl)-2-azabicyclo[2.2.1]hept-3-yl]-1H-benzimidazol-5-yl}-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]heptane-5-carboxylate ethanedioate (1:1)	941-126-4	1499193-66-6	Active	Intermediate	Joint	Intermediate use only	09-06-2015	View substance registered dossier
tert-butyl (S)-2-carbamoylpyrrolidine-1-carboxylate	626-262-1	35150-07-3	Active	Intermediate	Joint	Intermediate use only	28-11-2017	View substance registered dossier
tert-butyl (triphenylphosphoranylidene) acetate	412-880-7	35000-38-5	Active	NONS	Joint	Tonnage data confidential	14-07-2011	View substance registered dossier
tert-butyl 1H-pyrrol-1-ylcarbamate	810-523-3	937046-95-2	Active	Intermediate	Individual	Intermediate use only	27-02-2018	View substance registered dossier
tert-butyl 1H-pyrrol-1-ylcarbamate	810-523-3	937046-95-2	Cease Manufacture	Intermediate	Individual	Cease manufacture	24-08-2015	View substance registered dossier
tert-butyl 2-[(2S,3S)-2-(benzyloxy)pentan-3-yl]hydrazinecarboxylate	606-022-2	184177-88-6	Active	Intermediate	Individual	Intermediate use only	30-05-2018	View substance registered dossier
Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate	429-080-9	-	Active	Full	Joint	≥ 1 to < 10 tonnes	12-10-2017	View substance registered dossier
Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate	429-080-9	-	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
tert-butyl 2-bromopropanoate	675-664-3	39149-80-9	Active	Intermediate	Joint	Intermediate use only	24-04-2018	View substance registered dossier
tert-butyl 2-ethylperoxyhexanoate	221-110-7	3006-82-4	Active	Full	Joint	≥ 1 000 to < 10 000 tonnes	14-10-2020	View substance registered dossier
tert-butyl 2-hydroxyisobutyrate	252-952-3	36293-63-7	Active	Intermediate	Joint	Intermediate use only	08-11-2017	View substance registered dossier
tert-butyl 2-oxopyrrolidine-1-carboxylate	617-776-7	85909-08-6	Active	Intermediate	Joint	Intermediate use only	05-03-2020	View substance registered dossier
tert-butyl 2-{(2S,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-4-phenylbutyl}-2-[4-(pyridin-2-yl)benzyl]hydrazinecarboxylate	606-396-7	198904-86-8	Active	Full	Joint	≥ 1 to < 10 tonnes	24-04-2018	View substance registered dossier
tert-butyl 3,5,5-trimethylperoxyhexanoate	236-050-7	13122-18-4	Active	Full	Joint	≥ 1 000 to < 10 000 tonnes	12-11-2020	View substance registered dossier
tert-butyl 3-(6-amino-3-methylpyridin-2-yl)benzoate	800-303-5	1083057-14-0	Active	Intermediate	Joint	Intermediate use only	21-10-2014	View substance registered dossier
tert-butyl 3-[6-({[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl}amino)-3-methylpyridin-2-yl]benzoate	800-308-2	1160221-25-9	Active	Intermediate	Joint	Intermediate use only	21-10-2014	View substance registered dossier
Tert-butyl 3-Cyano-4-oxo-pyrrolidine-1-carboxylate	700-004-9	175463-32-8	Active	Intermediate	Individual	Intermediate use only	12-02-2009	View substance registered dossier
Tert-butyl 3-oxoazetidine-1-carboxylate	627-725-0	398489-26-4	Cease Manufacture	Intermediate	Individual	Cease manufacture	28-07-2014	View substance registered dossier
tert-butyl 3-oxobutanoate	216-904-5	1694-31-1	Active	Full	Joint	≥ 10 to < 100 tonnes	07-05-2018	View substance registered dossier
tert-butyl 3-oxobutanoate	216-904-5	1694-31-1	Active	Intermediate	Joint	Intermediate use only	26-03-2018	View substance registered dossier
tert-butyl 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate	942-231-8	1628047-90-4	Active	Intermediate	Joint	Intermediate use only	27-11-2015	View substance registered dossier
tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate	801-163-8	571189-16-7	Active	Intermediate	Joint	Intermediate use only	22-11-2018	View substance registered dossier
tert-Butyl 4-({6-[7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino}pyridin-3-yl)piperazine-1-carboxylate	810-753-4	1374639-78-7	No longer Valid	Full	Individual	No longer valid	27-08-2019	View substance registered dossier
tert-butyl 4-[(E)-3-(dimethylamino)prop-2-enoyl]piperidine-1-carboxylate	859-135-6	1799799-87-3	Active	Intermediate	Individual	Intermediate use only	27-10-2020	View substance registered dossier
tert-butyl 4-bromo-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate	942-459-8	1628047-84-6	Active	Intermediate	Joint	Intermediate use only	23-11-2015	View substance registered dossier
tert-butyl 4-bromo-2-fluorobenzoate	810-257-8	889858-12-2	Active	Intermediate	Joint	Intermediate use only	23-11-2015	View substance registered dossier
tert-butyl 4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine-1-carboxylate	941-919-5	1228780-71-9	Active	Intermediate	Joint	Intermediate use only	27-11-2015	View substance registered dossier
tert-butyl 6-cyano-2-(2-{4-ethyl-3-[4-(morpholin-4-yl)piperidin-1-yl]phenyl}propan-2-yl)-1H-indole-3-carboxylate hydrochloride (1:1)	813-852-0	1256584-77-6	Active	Intermediate	Individual	Intermediate use only	22-03-2017	View substance registered dossier
tert-butyl 6-cyano-2-[2-(4-ethyl-3-iodophenyl)propan-2-yl]-1H-indole-3-carboxylate	812-677-7	1256584-75-4	Active	Intermediate	Individual	Intermediate use only	07-07-2016	View substance registered dossier
tert-Butyl [(1R,2S,5S)-2-[[2-[(5-chloropyridin-2-yl)amino]-2-oxoacetyl]amino]-5-(dimethylaminocarbonyl)cyclohexyl]carbamate	836-116-0	480452-36-6	Active	Intermediate	Joint	Intermediate use only	09-10-2020	View substance registered dossier

Showing 24,151 - 24,200 of 25,859 results.

Registrant/Supplier	Address	Country	Registration Status	Name	EC / List no.	CAS no.	Last update year	Details
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Cease Manufacture	tert-butyl (2-cyano-1H-pyrrol-1-yl)carbamate	810-524-9	937046-96-3	2016	View substance registered dossier
Minakem Dunkerque Production	224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France	France	Active	tert-butyl (2-cyano-1H-pyrrol-1-yl)carbamate	810-524-9	937046-96-3	-	View substance registered dossier
DIPHARMA FRANCIS srl	Bissone, 5 20021 Baranzate Milano Italy	Italy	Active	tert-butyl (2S)-2-(3-fluoro-4-phenylphenyl)propanoate	945-962-0	-	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	tert-butyl (2S)-2-(4-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate	813-157-2	1007882-59-8	-	View substance registered dossier
Swords Laboratories	Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland	Ireland	Active	tert-butyl (2S)-2-[4-(4'-{2-[(2S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl]-1H-imidazol-5-yl}biphenyl-4-yl)-1H-imidazol-2-yl]pyrrolidine-1-carboxylate	941-432-8	-	-	View substance registered dossier
[Confidential]	-	-	-	tert-butyl (2S)-2-carbamoyl-2,3-dihydropyrrole-1-carboxylate	615-204-0	709031-38-9	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	tert-butyl (2S)-2-{4-[(6S)-10-{2-[(2S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl]-1H-imidazol-5-yl}-6-phenylindolo[1,2-c][1,3]benzoxazin-3-yl]-1H-imidazol-2-yl}pyrrolidine-1-carboxylate	813-165-6	1369595-05-0	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	tert-butyl (2S,4S)-2-[4-(2-{(2S,5S)-1-[N-(methoxycarbonyl)-L-valyl]-5-methylpyrrolidin-2-yl}-1,11-dihydro[2]benzopyrano[4',3':6,7]naphtho[1,2-d]imidazol-9-yl)-1H-imidazol-2-yl]-4-(methoxymethyl)pyrrolidine-1-carboxylate	807-100-0	1378391-45-7	-	View substance registered dossier
LA MESTA CHIMIE FINE	1336 Route de l'Estéron 06830 GILETTE France	France	Active	tert-butyl (3-{[2-(1H-imidazol-4-yl)ethyl]amino}-3-oxopropyl)carbamate	813-660-7	143885-59-0	-	View substance registered dossier
ORGAPHARM	Rue du Moulin de la Canne 45300 PITHIVIERS France	France	Active	tert-butyl (3R)-3-hydroxypyrrolidine-1-carboxylate	629-335-6	109431-87-0	-	View substance registered dossier
Lek Pharmaceuticals d.d.	Verovskova 57 1526 Ljubljana Slovenia	Slovenia	Active	tert-butyl (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoate	609-144-4	355806-00-7	2020	View substance registered dossier
EGIS Pharmaceuticals PLC	Keresztúri út 30-38 H-1106 Budapest Hungary	Hungary	Active	tert-butyl (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoate	609-144-4	355806-00-7	-	View substance registered dossier
ORGAPHARM	Rue du Moulin de la Canne 45300 PITHIVIERS France	France	Active	tert-butyl (3S)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]pyrrolidine-1-carboxylate	861-843-5	1383793-75-6	2020	View substance registered dossier
Novartis Integrated Services Limited	Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland	Ireland	Active	tert-butyl (3S,5S)-3-isopropyl-5-((2S,4S)-tetrahydro-4-isopropyl-5-oxo-furan-2-yl)-2-oxo-pyrrolidine-carboxylate	472-680-0	-	2010; 2019	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority.	-	-	Active	tert-butyl (3S,5S)-3-isopropyl-5-((2S,4S)-tetrahydro-4-isopropyl-5-oxo-furan-2-yl)-2-oxo-pyrrolidine-carboxylate	472-680-0	-	-	View substance registered dossier
Patheon Austria GmbH & Co KG	St. Peterstrasse 25 A-4020 Linz Austria	Austria	Active	tert-butyl (3S,6S)-3-((tert-butyldimethylsilyl)oxy)-6-chloro-6-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)hexanoate	811-363-7	1681053-96-2	-	View substance registered dossier
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Cease Manufacture	tert-butyl (4-bromo-2-cyano-1H-pyrrol-1-yl)carbamate	810-525-4	937047-04-6	2016	View substance registered dossier
Minakem Dunkerque Production	224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France	France	Active	tert-butyl (4-bromo-2-cyano-1H-pyrrol-1-yl)carbamate	810-525-4	937047-04-6	-	View substance registered dossier
Krka, d. d., Novo mesto	Smarjeska cesta 6 SI-8501 Novo mesto Slovenia	Slovenia	Active	tert-butyl (4R)-cis-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate	425-780-3	125971-94-0	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority.	-	-	Active	tert-butyl (4R)-cis-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate	425-780-3	125971-94-0	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority.	-	-	Active	tert-butyl (5S,6R,7R)-3-bromomethyl-5,8-dioxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	407-620-4	33610-13-8	-	View substance registered dossier
Esteve Quimica, S.A.	Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain	Spain	Active	tert-butyl (6S)-6-[4-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]heptane-5-carboxylate	939-899-8	1441670-89-8	2015	View substance registered dossier
Esteve Quimica, S.A.	Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain	Spain	Active	tert-butyl (6S)-6-[4-(7-{2-[(1R,3S,4S)-2-(tert-butoxycarbonyl)-2-azabicyclo[2.2.1]hept-3-yl]-1H-benzimidazol-5-yl}-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]heptane-5-carboxylate ethanedioate (1:1)	941-126-4	1499193-66-6	2015	View substance registered dossier
[Confidential]	-	-	-	tert-butyl (S)-2-carbamoylpyrrolidine-1-carboxylate	626-262-1	35150-07-3	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	tert-butyl (triphenylphosphoranylidene) acetate	412-880-7	35000-38-5	-	View substance registered dossier
Glaxo Operations UK	Glaxo Wellcome House Berkeley Avenue UB6 0NN Greenford Middlesex United Kingdom	United Kingdom	No longer Valid	tert-butyl (triphenylphosphoranylidene) acetate	412-880-7	35000-38-5	2021	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	tert-butyl (triphenylphosphoranylidene) acetate	412-880-7	35000-38-5	2011	View substance registered dossier
Minakem Dunkerque Production	224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France	France	Active	tert-butyl 1H-pyrrol-1-ylcarbamate	810-523-3	937046-95-2	-	View substance registered dossier
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Cease Manufacture	tert-butyl 1H-pyrrol-1-ylcarbamate	810-523-3	937046-95-2	2016	View substance registered dossier
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Active	tert-butyl 2-[(2S,3S)-2-(benzyloxy)pentan-3-yl]hydrazinecarboxylate	606-022-2	184177-88-6	-	View substance registered dossier
Swords Laboratories	Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland	Ireland	Active	Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate	429-080-9	-	2010; 2017	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority.	-	-	Active	Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate	429-080-9	-	-	View substance registered dossier
Amri Italy S.r.l.	VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy	Italy	Active	Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate	429-080-9	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority.	-	-	Active	Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate	429-080-9	-	-	View substance registered dossier
DIPHARMA FRANCIS srl	Bissone, 5 20021 Baranzate Milano Italy	Italy	Active	tert-butyl 2-bromopropanoate	675-664-3	39149-80-9	-	View substance registered dossier
TSE, OR for Tosoh Finechem	Rembrandt Tower Amstelplein 1 1096 HA Amsterdam Netherlands	Netherlands	Active	tert-butyl 2-bromopropanoate	675-664-3	39149-80-9	-	View substance registered dossier
B-Lands Consulting (811725-2)	5 Place Robert Schuman - BP 1516 38025 Grenoble France France	France	Active	tert-butyl 2-bromopropanoate	675-664-3	39149-80-9	-	View substance registered dossier
3M Belgium BVBA/SPRL	Hermeslaan 7 1831 Diegem Belgium	Belgium	Active	tert-butyl 2-ethylperoxyhexanoate	221-110-7	3006-82-4	-	View substance registered dossier
United Initiators GmbH	Dr. Gustav-Adolph-Str. 3 D-82049 Pullach Bavaria Germany	Germany	Active	tert-butyl 2-ethylperoxyhexanoate	221-110-7	3006-82-4	2011; 2014; 2016; 2019; 2020	View substance registered dossier
Axalta Coating Systems Germany GmbH & Co. KG	Christbusch 25 42285 Wuppertal Germany	Germany	Active	tert-butyl 2-ethylperoxyhexanoate	221-110-7	3006-82-4	-	View substance registered dossier
Valspar b.v.	Zuiveringweg 89 8243 PE Lelystad Netherlands	Netherlands	Active	tert-butyl 2-ethylperoxyhexanoate	221-110-7	3006-82-4	2020	View substance registered dossier
SCAS Europe S.A./N.V.	Leonardo Da Vincilaan 19 B-1831 Diegem Belgium	Belgium	Active	tert-butyl 2-ethylperoxyhexanoate	221-110-7	3006-82-4	-	View substance registered dossier
PERGAN GmbH	Schlavenhorst 71 46395 Bocholt NRW Germany	Germany	Active	tert-butyl 2-ethylperoxyhexanoate	221-110-7	3006-82-4	2016	View substance registered dossier
Perga-Chem GmbH	Vor dem Gröperntor 20 06484 Quedlinburg Germany	Germany	Active	tert-butyl 2-ethylperoxyhexanoate	221-110-7	3006-82-4	2013; 2017	View substance registered dossier
ARKEMA Gmbh	Tersteegenstrasse 28 40401 Düsseldorf Germany	Germany	Active	tert-butyl 2-ethylperoxyhexanoate	221-110-7	3006-82-4	2016; 2017; 2019	View substance registered dossier
Nouryon Chemicals NV/SA	Parc Industriel de Ghlin Zone A 7011 Ghlin Mons Belgium	Belgium	Active	tert-butyl 2-ethylperoxyhexanoate	221-110-7	3006-82-4	2012; 2013; 2017; 2019	View substance registered dossier
PCAS	21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France	France	Active	tert-butyl 2-hydroxyisobutyrate	252-952-3	36293-63-7	-	View substance registered dossier
Chr. Olesen ChemPharm GmbH	Gustav-Becker-Strasse 20B 21218 Seevetal Germany	Germany	Active	tert-butyl 2-oxopyrrolidine-1-carboxylate	617-776-7	85909-08-6	-	View substance registered dossier
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Active	tert-butyl 2-oxopyrrolidine-1-carboxylate	617-776-7	85909-08-6	2020	View substance registered dossier
SK BIOTEK IRELAND LIMITED	Watery Lane Swords K67 AY91 Swords Co. Dublin Ireland	Ireland	Active	tert-butyl 2-{(2S,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-4-phenylbutyl}-2-[4-(pyridin-2-yl)benzyl]hydrazinecarboxylate	606-396-7	198904-86-8	2018	View substance registered dossier
Swords Laboratories	Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland	Ireland	Active	tert-butyl 2-{(2S,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-4-phenylbutyl}-2-[4-(pyridin-2-yl)benzyl]hydrazinecarboxylate	606-396-7	198904-86-8	2018	View substance registered dossier
Siegfried St. Vulbas SAS	530, allée de la Luye 01150 SAINT VULBAS France	France	Active	tert-butyl 2-{(2S,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-4-phenylbutyl}-2-[4-(pyridin-2-yl)benzyl]hydrazinecarboxylate	606-396-7	198904-86-8	-	View substance registered dossier
PERGAN GmbH	Schlavenhorst 71 46395 Bocholt NRW Germany	Germany	Active	tert-butyl 3,5,5-trimethylperoxyhexanoate	236-050-7	13122-18-4	2017	View substance registered dossier
Nouryon Chemicals NV/SA	Parc Industriel de Ghlin Zone A 7011 Ghlin Mons Belgium	Belgium	Active	tert-butyl 3,5,5-trimethylperoxyhexanoate	236-050-7	13122-18-4	2012; 2014; 2017; 2019	View substance registered dossier
3M Belgium BVBA/SPRL	Hermeslaan 7 1831 Diegem Belgium	Belgium	Active	tert-butyl 3,5,5-trimethylperoxyhexanoate	236-050-7	13122-18-4	-	View substance registered dossier
REACH GLOBAL SERVICES S.A	Rond Point Schuman, 6 B-1040 Brussels Belgium	Belgium	Active	tert-butyl 3,5,5-trimethylperoxyhexanoate	236-050-7	13122-18-4	-	View substance registered dossier
Perga-Chem GmbH	Vor dem Gröperntor 20 06484 Quedlinburg Germany	Germany	Active	tert-butyl 3,5,5-trimethylperoxyhexanoate	236-050-7	13122-18-4	2017	View substance registered dossier
United Initiators GmbH	Dr. Gustav-Adolph-Str. 3 D-82049 Pullach Bavaria Germany	Germany	Active	tert-butyl 3,5,5-trimethylperoxyhexanoate	236-050-7	13122-18-4	2011; 2014; 2017; 2020	View substance registered dossier
ARKEMA Gmbh	Tersteegenstrasse 28 40401 Düsseldorf Germany	Germany	Active	tert-butyl 3,5,5-trimethylperoxyhexanoate	236-050-7	13122-18-4	2016; 2017	View substance registered dossier
Esteve Quimica, S.A.	Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain	Spain	Active	tert-butyl 3-(6-amino-3-methylpyridin-2-yl)benzoate	800-303-5	1083057-14-0	2014	View substance registered dossier
Esteve Quimica, S.A.	Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain	Spain	Active	tert-butyl 3-[6-({[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl}amino)-3-methylpyridin-2-yl]benzoate	800-308-2	1160221-25-9	2014	View substance registered dossier
PROCOS SpA	via Matteotti 249 28062 Cameri Piemonte Italy	Italy	Active	Tert-butyl 3-Cyano-4-oxo-pyrrolidine-1-carboxylate	700-004-9	175463-32-8	-	View substance registered dossier
MINAKEM S.A.S.	Chemin des Lilas, 145 59310 Beuvry-la-Forêt France	France	Cease Manufacture	Tert-butyl 3-oxoazetidine-1-carboxylate	627-725-0	398489-26-4	2021	View substance registered dossier
Global Product Compliance (Europe) AB	IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden	Sweden	Active	tert-butyl 3-oxobutanoate	216-904-5	1694-31-1	2018	View substance registered dossier
Valtris Specialty Chemicals Ltd	Lankro Way PO Box 1 , Eccles M30 OLX Manchester Greater Manchester United Kingdom	United Kingdom	No longer Valid	tert-butyl 3-oxobutanoate	216-904-5	1694-31-1	2021	View substance registered dossier
Eastman Chemical B.V.	Watermanweg 70 3067 GG Rotterdam Netherlands	Netherlands	Active	tert-butyl 3-oxobutanoate	216-904-5	1694-31-1	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	tert-butyl 3-oxobutanoate	216-904-5	1694-31-1	-	View substance registered dossier
Lonza Cologne GmbH - REACH	Nattermannallee 1 50829 Cologne Germany	Germany	Active	tert-butyl 3-oxobutanoate	216-904-5	1694-31-1	2017	View substance registered dossier
[Confidential]	-	-	-	tert-butyl 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate	942-231-8	1628047-90-4	-	View substance registered dossier
PCAS	21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France	France	Active	tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate	801-163-8	571189-16-7	2015; 2017	View substance registered dossier
Pfizer Ireland Pharmaceuticals	n/a P43 X3336 Ringaskiddy Cork Ireland	Ireland	Active	tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate	801-163-8	571189-16-7	-	View substance registered dossier
EXPANSIA	Route d'Avignon BP 6 30390 ARAMON France	France	Active	tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate	801-163-8	571189-16-7	-	View substance registered dossier
MinAscent Leuna Production GmbH	Am Haupttor Gebäude 4208 06237 Leuna Germany	Germany	Active	tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate	801-163-8	571189-16-7	-	View substance registered dossier
Novartis Grimsby Limited	Moody Lane, Pyewipe DN31 2SR Grimsby N.E. Lincolnshire United Kingdom	United Kingdom	No longer Valid	tert-Butyl 4-({6-[7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino}pyridin-3-yl)piperazine-1-carboxylate	810-753-4	1374639-78-7	2021	View substance registered dossier
Siegfried St. Vulbas SAS	530, allée de la Luye 01150 SAINT VULBAS France	France	Active	tert-butyl 4-[(E)-3-(dimethylamino)prop-2-enoyl]piperidine-1-carboxylate	859-135-6	1799799-87-3	-	View substance registered dossier
[Confidential]	-	-	-	tert-butyl 4-bromo-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate	942-459-8	1628047-84-6	-	View substance registered dossier
[Confidential]	-	-	-	tert-butyl 4-bromo-2-fluorobenzoate	810-257-8	889858-12-2	-	View substance registered dossier
[Confidential]	-	-	-	tert-butyl 4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine-1-carboxylate	941-919-5	1228780-71-9	-	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Active	tert-butyl 6-cyano-2-(2-{4-ethyl-3-[4-(morpholin-4-yl)piperidin-1-yl]phenyl}propan-2-yl)-1H-indole-3-carboxylate hydrochloride (1:1)	813-852-0	1256584-77-6	-	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Active	tert-butyl 6-cyano-2-[2-(4-ethyl-3-iodophenyl)propan-2-yl]-1H-indole-3-carboxylate	812-677-7	1256584-75-4	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	tert-Butyl [(1R,2S,5S)-2-[[2-[(5-chloropyridin-2-yl)amino]-2-oxoacetyl]amino]-5-(dimethylaminocarbonyl)cyclohexyl]carbamate	836-116-0	480452-36-6	-	View substance registered dossier

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Last updated 13 May 2021. Database contains 23207 unique substances and contains information from 102702 dossiers.

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