Registered substances

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM. More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.

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Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration

Showing 8,401 - 8,500 of 26,865 results.

Name	EC / List no.	CAS no.	Registration Status	Registration type	Submission type	Total tonnage band	Last Updated	Details
4-[(3-chloropropanoyl)oxy]benzoic acid	609-278-3	366448-45-5	Active	Intermediate	Joint	Intermediate use only	30-10-2020	View substance registered dossier
4-[(4,8-disulpho-2-naphthyl)azo]naphthalene-1-diazonium chloride	267-995-3	67969-94-2	Active	Intermediate	Joint	Intermediate use only	11-06-2019	View substance registered dossier
4-[(4-amino-5-methoxy-o-tolyl)azo]-5-[(phenylsulphonyl)oxy]naphthalene-2,7-disulphonic acid	204-190-8	117-44-2	Active	Intermediate	Joint	Intermediate use only	15-03-2018	View substance registered dossier
4-[(4-Fluorophenylimino)methyl]phenol	438-950-7	-	Active	Intermediate	Joint	Intermediate use only	25-07-2019	View substance registered dossier
4-[(4-methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride	600-728-4	106261-49-8	Active	Intermediate	Individual	Intermediate use only	27-11-2014	View substance registered dossier
4-[(5-{[(benzyloxy)carbonyl]amino}pentyl)(hydroxy)amino]-4-oxobutanoic acid	600-744-1	106410-46-2	Active	Intermediate	Joint	Intermediate use only	07-10-2019	View substance registered dossier
4-[(6-amino-1-hydroxy-3-sulpho-2-naphthyl)azo]-3-hydroxy-7-nitronaphthalene-1-sulphonic acid	204-203-7	117-69-1	Cease Manufacture	Intermediate	Joint	Cease manufacture	23-03-2012	View substance registered dossier
4-[(E)-2-nitroethenyl]-1H-indole	634-890-2	49839-99-8	Active	Intermediate	Joint	Intermediate use only	23-04-2018	View substance registered dossier
4-[(EZ)-3-(3-Chloro-5-trifluoromethylphenyl)-4,4,4-trifluorobut-2-enoyl]-naphthalene-1-carboxylic acid [(2,2,2-trifluoroethylcarbamoyl)-methyl]amide	807-881-8	1125812-56-7	Active	Intermediate	Joint	Intermediate use only	25-02-2015	View substance registered dossier
4-[2-((6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-ylsulfanyl)thiazole-4-yl]-1-methyl-pyridiniumchloride monohydrochloride AMPA	447-990-4	-	Active	Intermediate	Joint	Intermediate use only	16-10-2019	View substance registered dossier
4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid INTERMEDIATE 202723	429-790-9	137281-39-1	Active	Intermediate	Individual	Intermediate use only	31-10-2017	View substance registered dossier
4-[2-(Cyclopropylmethoxy)ethyl]phenol	440-910-9	-	Active	Intermediate	Joint	Intermediate use only	12-10-2018	View substance registered dossier
4-[2-(diethylamino)ethoxy]benzophenone	212-348-2	796-77-0	Active	Intermediate	Joint	Intermediate use only	13-10-2016	View substance registered dossier
4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol	700-516-2	93413-62-8	Active	Intermediate	Joint	Intermediate use only	07-04-2021	View substance registered dossier
4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol	700-516-2	93413-62-8	Active	Intermediate	Individual	Intermediate use only	17-04-2013	View substance registered dossier
4-[2-(methoxymethyl)-3-methyl-1-methylene-but-2-enyl]-1H-tetrazol-5-one	826-908-4	1472631-98-3	Active	Intermediate	Joint	Intermediate use only	28-10-2020	View substance registered dossier
4-[2-[(phenylmethyl)amino]propyl]- Phenol	608-112-7	27566-05-8	Active	Intermediate	Individual	Intermediate use only	08-01-2014	View substance registered dossier
4-[2-[4-(2-benzoxazoleyl)phenyl]vinyl]benzoic acid	225-303-7	4763-79-5	Active	Intermediate	Joint	Intermediate use only	28-03-2019	View substance registered dossier
4-[2-Ethoxy-5-(4-methyl-1-piperazinylsulfonyl)benzamido]-1-3-propyl-1H-pyrazole-5-carboxamide	639-263-7	200575-15-1	Active	Intermediate	Individual	Intermediate use only	12-04-2017	View substance registered dossier
4-[2-piperidinoethoxy]benzoic acid hydrochloride	282-882-9	84449-80-9	Active	Intermediate	Joint	Intermediate use only	18-05-2018	View substance registered dossier
4-[3-(2,5-Dichlor-4,6-dimethyl-1-oxido-3-pyridinyl)-1,2,4-oxadiazol-5-yl]-2-methoxy-6-nitrophenol	826-271-2	1402714-41-3	Active	Intermediate	Joint	Intermediate use only	23-07-2019	View substance registered dossier
4-[3-iodo-1-(1-methylethyl)-1H-pyrazol-4-yl]-2-pyrimidinamine	826-700-3	1269440-54-1	Active	Intermediate	Joint	Intermediate use only	28-05-2020	View substance registered dossier
4-[4-(4-aminophenyl)piperazin-1-yl]phenol	616-147-4	74853-08-0	Active	Intermediate	Individual	Intermediate use only	29-06-2017	View substance registered dossier
4-[4-(4-aminophenyl)piperazin-1-yl]phenol	616-147-4	74853-08-0	Active	Intermediate	Joint	Intermediate use only	15-05-2018	View substance registered dossier
4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide hydrochloride	692-722-3	835621-07-3	Cease Manufacture	Intermediate	Individual	Cease manufacture	15-12-2014	View substance registered dossier
4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-α,α-dimethyl-ethyl ester benzeneacetic acid	616-391-1	76812-02-7	Active	Intermediate	Joint	Intermediate use only	15-03-2022	View substance registered dossier
4-[[(2-aminophenyl)methyl]amino]cyclohexyl acetate	298-842-9	93839-71-5	Active	Intermediate	Joint	Intermediate use only	21-03-2011	View substance registered dossier
4-[[2-chloro-5-(trifluoromethyl)phenyl]azo]-3-hydroxy-2-naphthoic acid	257-777-6	52238-94-5	Active	Intermediate	Joint	Intermediate use only	11-06-2019	View substance registered dossier
4-[[4-(dimethylamino)phenyl][4-(methylimino)cyclohexa-2,5-dien-1-ylidene]methyl]-N,N-dimethylaniline monohydrochloride	210-042-3	603-47-4	Active	Intermediate	Joint	Intermediate use only	25-05-2018	View substance registered dossier
4-[bis(isopropyl)amino]-2,2-diphenylbutyronitrile	201-005-2	77-11-2	Active	Intermediate	Joint	Intermediate use only	21-12-2016	View substance registered dossier
4-acetamido-5-(ethylsulphonyl)-2-methoxybenzoic acid	302-772-7	94134-06-2	Active	Intermediate	Joint	Intermediate use only	27-03-2018	View substance registered dossier
4-acetamidobenzoic acid, compound with 1-(dimethylamino)propan-2-ol (1:1)	263-361-5	61990-51-0	Active	Intermediate	Joint	Intermediate use only	02-02-2021	View substance registered dossier
4-acetilammino-N-((1-etil-2pirrolidinil)metil) -5 etilsulfonil-2-metossi benzamide	925-003-2	-	Active	Intermediate	Joint	Intermediate use only	27-03-2018	View substance registered dossier
4-acetyl-2-methylbenzoic acid	856-079-4	55860-35-0	Active	Intermediate	Joint	Intermediate use only	15-06-2022	View substance registered dossier
4-Acetyl-2-methylbenzoyl chloride	870-641-6	1095275-05-0	Active	Intermediate	Joint	Intermediate use only	08-11-2021	View substance registered dossier
4-acetyl-N-[(4R)-2-ethyl-3-oxo-1,2-oxazolidin-4-yl]-2-methylbenzamide	875-863-7	1309959-52-1	Active	Intermediate	Joint	Intermediate use only	28-06-2022	View substance registered dossier
4-acetyl-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]naphthalene-1-carboxamide	807-880-2	1125812-54-5	Active	Intermediate	Joint	Intermediate use only	18-10-2016	View substance registered dossier
4-Acetylnaphthalene-1-carboxylic acid	807-884-4	131986-05-5	Active	Intermediate	Joint	Intermediate use only	26-04-2017	View substance registered dossier
4-allylveratrole	202-223-0	93-15-2	Active	Intermediate	Joint	Intermediate use only	01-03-2019	View substance registered dossier
4-amino-1-Methyl-3-n-propyl-5-pyrazolecarboxamide hydrochloride	938-723-7	-	Active	Intermediate	Joint	Intermediate use only	19-07-2021	View substance registered dossier
4-amino-10-methyl folic acid ethylester hydroiodide	617-385-1	82784-24-5	Active	Intermediate	Individual	Intermediate use only	12-11-2010	View substance registered dossier
4-Amino-2,3-dichlorophenol	464-070-8	-	Active	Intermediate	Joint	Intermediate use only	28-09-2021	View substance registered dossier
4-amino-2,4-dihydro-5-(1-methylethyl)-3H-1,2,4-triazol-3-one	689-404-1	96240-10-7	Active	Intermediate	Joint	Intermediate use only	11-06-2021	View substance registered dossier
4-amino-2,4-dihydro-5-(1-methylethyl)-3H-1,2,4-triazol-3-one	689-404-1	96240-10-7	Cease Manufacture	Intermediate	Individual	Cease manufacture	25-08-2011	View substance registered dossier
4-amino-2,5-dichloro-N,N-dimethylbenzenesulphonamide	247-501-2	26175-68-8	Active	Intermediate	Individual	Intermediate use only	07-10-2011	View substance registered dossier
4-amino-2,5-dichlorobenzenesulphonic acid	201-836-0	88-50-6	Active	Intermediate	Joint	Intermediate use only	17-01-2018	View substance registered dossier
4-amino-2,5-dimethoxy-N-methylbenzenesulphonamide	256-435-3	49701-24-8	Active	Intermediate	Joint	Intermediate use only	30-01-2014	View substance registered dossier
4-amino-2,5-dimethoxy-N-phenylbenzenesulphonamide	257-821-4	52298-44-9	Active	Intermediate	Joint	Intermediate use only	04-05-2016	View substance registered dossier
4-amino-2-(trifluoromethyl)benzonitrile	700-293-1	654-70-6	Active	Intermediate	Individual	Intermediate use only	02-10-2008	View substance registered dossier
4-amino-2-(trifluoromethyl)benzonitrile	700-293-1	654-70-6	No longer Valid	Intermediate	Individual	No longer valid	24-05-2013	View substance registered dossier
4-amino-2-(trifluoromethyl)benzonitrile	700-293-1	654-70-6	Active	Intermediate	Individual	Intermediate use only	15-10-2010	View substance registered dossier
4-amino-2-(trifluoromethyl)benzonitrile	700-293-1	654-70-6	Active	Intermediate	Joint	Intermediate use only	06-03-2019	View substance registered dossier
4-amino-2-chlorobenzonitrile	244-114-0	20925-27-3	Active	Intermediate	Joint	Intermediate use only	06-05-2022	View substance registered dossier
4-Amino-2-fluoro-benzamide	809-434-2	609783-45-1	Active	Intermediate	Joint	Intermediate use only	08-03-2023	View substance registered dossier
4-amino-2-methylpyrimidine-5-carbonitrile	211-814-2	698-29-3	Active	Intermediate	Joint	Intermediate use only	09-09-2019	View substance registered dossier
4-amino-2-methylpyrimidine-5-methylamine	202-384-7	95-02-3	Active	Intermediate	Joint	Intermediate use only	19-12-2019	View substance registered dossier
4-amino-3-(4-phenoxyphenyl)-1-[(3R)-piperidin-3-yl]-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one	954-509-6	1971921-35-3	Active	Intermediate	Joint	Intermediate use only	22-09-2021	View substance registered dossier
4-amino-3-fluorophenol FAP	402-230-0	399-95-1	Active	Intermediate	Individual	Intermediate use only	23-05-2014	View substance registered dossier
4-amino-3-hydroxybenzoic acid	629-073-2	2374-03-0	Active	Intermediate	Joint	Intermediate use only	08-02-2019	View substance registered dossier
4-amino-3-nitrobenzenesulphonic acid	210-495-7	616-84-2	Active	Intermediate	Joint	Intermediate use only	20-02-2018	View substance registered dossier
4-amino-5-(ethylsulphonyl)-o-anisic acid	275-833-8	71675-87-1	Active	Intermediate	Joint	Intermediate use only	25-05-2018	View substance registered dossier
4-amino-5-(ethylthio)-o-anisic acid	275-832-2	71675-86-0	Active	Intermediate	Joint	Intermediate use only	10-04-2018	View substance registered dossier
4-amino-5-[(phenylsulphonyl)oxy]naphthalene-2,7-disulphonic acid	201-460-7	83-23-8	Active	Intermediate	Joint	Intermediate use only	15-03-2018	View substance registered dossier
4-Amino-5-chloro-2,1,3-benzothiodiazole	457-490-8	-	Active	Intermediate	Individual	Intermediate use only	01-04-2015	View substance registered dossier
4-amino-5-hydroxynaphthalene-2,7-disulphonic acid	201-975-7	90-20-0	Active	Intermediate	Joint	Intermediate use only	13-03-2013	View substance registered dossier
4-amino-5-methoxy-N,2-dimethylbenzenesulphonamide	256-380-5	49564-57-0	Active	Intermediate	Joint	Intermediate use only	17-10-2011	View substance registered dossier
4-amino-5-methylpyridin-2(1H)-one	682-818-3	95306-64-2	Active	Intermediate	Joint	Intermediate use only	10-12-2020	View substance registered dossier
4-amino-6-chlorobenzene-1,3-disulphonamide	204-463-1	121-30-2	Active	Intermediate	Joint	Intermediate use only	31-05-2018	View substance registered dossier
4-amino-6-chlorobenzene-1,3-disulphonamide	204-463-1	121-30-2	Active	Intermediate	Individual	Intermediate use only	05-03-2013	View substance registered dossier
4-amino-6-chlorotoluene-3-sulphonic acid	201-837-6	88-51-7	Active	Intermediate	Individual	Intermediate use only	30-05-2013	View substance registered dossier
4-amino-6-chlorotoluene-3-sulphonic acid	201-837-6	88-51-7	Active	Intermediate	Joint	Intermediate use only	18-06-2020	View substance registered dossier
4-amino-6-chlorotoluene-3-sulphonic acid	201-837-6	88-51-7	No longer Valid	Intermediate	Individual	No longer valid	18-07-2012	View substance registered dossier
4-amino-N,N-diethylaniline	202-214-1	93-05-0	Active	Intermediate	Individual	Intermediate use only	02-06-2015	View substance registered dossier
4-amino-N-(2-ethylhexyl)benzenesulphonamide	258-799-9	53817-09-7	Active	Intermediate	Individual	Intermediate use only	15-01-2015	View substance registered dossier
4-amino-N-(2-methylquinolin-8-yl)benzenesulfonamide	700-562-3	909782-32-7	Active	Intermediate	Individual	Intermediate use only	07-05-2015	View substance registered dossier
4-amino-N-(4-amino-6-oxo-5H-pyrimidin-2-yl)benzenesulfonamide	605-738-2	174863-37-7	Active	Intermediate	Joint	Intermediate use only	22-11-2017	View substance registered dossier
4-Amino-N-(terc-butyl)benzenesulfonamide	687-656-7	209917-48-6	Active	Intermediate	Joint	Intermediate use only	21-12-2017	View substance registered dossier
4-Amino-N-[3-(diethylamino)propyl]benzamid, hydrochloride	814-672-5	109342-99-6	Cease Manufacture	Intermediate	Joint	Cease manufacture	12-02-2020	View substance registered dossier
4-amino-N-[3-(diethylamino)propyl]benzamide	700-444-1	106595-73-7	Active	Intermediate	Individual	Intermediate use only	16-07-2010	View substance registered dossier
4-amino-N-[4-(aminocarbonyl)phenyl]benzamide	277-874-7	74441-06-8	Active	Intermediate	Joint	Intermediate use only	03-06-2016	View substance registered dossier
4-aminoazobenzene	200-453-6	60-09-3	Active	Intermediate	Individual	Intermediate use only	09-12-2015	View substance registered dossier
4-Aminobenzoamidoxime	664-406-5	277319-62-7	Active	Intermediate	Joint	Intermediate use only	26-03-2019	View substance registered dossier
4-aminobenzoic acid	205-753-0	150-13-0	Active	Intermediate	Individual	Intermediate use only	19-08-2013	View substance registered dossier
4-aminobenzonitrile	212-850-1	873-74-5	Active	Intermediate	Joint	Intermediate use only	05-09-2019	View substance registered dossier
4-aminomethyl-2-methoxyphenol hydrochloride	230-468-3	7149-10-2	Active	Intermediate	Joint	Intermediate use only	20-04-2017	View substance registered dossier
4-aminonaphthalene-1-sulphonic acid	201-567-9	84-86-6	Active	Intermediate	Joint	Intermediate use only	16-03-2018	View substance registered dossier
4-aminophenol	204-616-2	123-30-8	Active	Intermediate	Individual	Intermediate use only	30-04-2014	View substance registered dossier
4-aminophenol	204-616-2	123-30-8	Active	Intermediate	Individual	Intermediate use only	16-05-2013	View substance registered dossier
4-aminosalicylic acid	200-613-5	65-49-6	Active	Intermediate	Joint	Intermediate use only	23-11-2022	View substance registered dossier
4-aminotoluene-2-sulphonanilide	201-221-7	79-72-1	Active	Intermediate	Joint	Intermediate use only	21-12-2016	View substance registered dossier
4-anilinophenol	204-538-9	122-37-2	Active	Intermediate	Joint	Intermediate use only	18-01-2018	View substance registered dossier
4-azidobutan-1-amine; (7,7-dimethyl-3-oxo-4-bicyclo[2.2.1]heptanyl)methanesulfonic acid	943-084-2	-	Active	Intermediate	Individual	Intermediate use only	10-03-2016	View substance registered dossier
4-benzyl-1-(2-hydroxymethylphenyl)-2-phenylpiperazine-fumarate	700-842-5	1192015-20-5	Active	Intermediate	Individual	Intermediate use only	21-05-2012	View substance registered dossier
4-benzyloxyaniline hydrochloride	257-170-6	51388-20-6	Active	Intermediate	Joint	Intermediate use only	16-10-2017	View substance registered dossier
4-bromo-1,2-dichlorobenzene	242-160-6	18282-59-2	Active	Intermediate	Joint	Intermediate use only	15-10-2019	View substance registered dossier
4-Bromo-1-chloro-2-(4-ethoxy-benzyl)-benzene	636-921-5	461432-23-5	Active	Intermediate	Joint	Intermediate use only	13-03-2018	View substance registered dossier
4-bromo-1-chloro-2-[(4-éthoxyphenyl)(phenylmethoxy)-methyl]-benzene	807-813-7	1298086-15-3	Active	Intermediate	Joint	Intermediate use only	22-09-2021	View substance registered dossier
4-bromo-2,3',4',5'-tetrafluoro-1,1'-biphenyl	936-926-5	-	Active	Intermediate	Joint	Intermediate use only	19-02-2018	View substance registered dossier
4-bromo-2,6-difluorobenzoic acid UQU-BR-F STUFE 1	457-940-3	183065-68-1	Cease Manufacture	Intermediate	Joint	Cease manufacture	05-07-2013	View substance registered dossier
4-Bromo-2,6-difluorobenzoyl chloride	803-879-6	497181-19-8	Active	Intermediate	Joint	Intermediate use only	13-12-2017	View substance registered dossier

Showing 8,401 - 8,500 of 26,865 results.

Registrant/Supplier	Address	Country	Registration Status	Name	EC / List no.	CAS no.	Last update year	Details
ORGANICA Feinchemie GmbH Wolfen	Ortsteil Wolfen Kunstseidestraße 5 06766 Bitterfeld-Wolfen Germany	Germany	Active	4-[(3-chloropropanoyl)oxy]benzoic acid	609-278-3	366448-45-5	-	View substance registered dossier
Synthesia, a.s.	Semtín103 53002 Pardubice Czech Republic	Czech Republic	Active	4-[(4,8-disulpho-2-naphthyl)azo]naphthalene-1-diazonium chloride	267-995-3	67969-94-2	2019	View substance registered dossier
Synthesia, a.s.	Semtín103 53002 Pardubice Czech Republic	Czech Republic	Active	4-[(4-amino-5-methoxy-o-tolyl)azo]-5-[(phenylsulphonyl)oxy]naphthalene-2,7-disulphonic acid	204-190-8	117-44-2	-	View substance registered dossier
Krka, d. d., Novo mesto	Smarjeska cesta 6 SI-8501 Novo mesto Slovenia	Slovenia	Active	4-[(4-Fluorophenylimino)methyl]phenol	438-950-7	-	-	View substance registered dossier
Pliva Hrvatska doo	Prilaz baruna Filipovića 25 10000 Zagreb Croatia	Croatia	Active	4-[(4-methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride	600-728-4	106261-49-8	-	View substance registered dossier
VALDEPHARM	Parc Industriel d'Incarville CS10606 27106 Val de Reuil France	France	Active	4-[(5-{[(benzyloxy)carbonyl]amino}pentyl)(hydroxy)amino]-4-oxobutanoic acid	600-744-1	106410-46-2	2012	View substance registered dossier
Menadiona SL	Pol Ind Mas Puigvert, Ctra Nacional II Km 680, 5 08389 Palafolls Barcelona Spain	Spain	Active	4-[(5-{[(benzyloxy)carbonyl]amino}pentyl)(hydroxy)amino]-4-oxobutanoic acid	600-744-1	106410-46-2	-	View substance registered dossier
Excella GmbH & Co. KG	Nuernberger Str. 12 90537 Feucht Germany	Germany	Active	4-[(5-{[(benzyloxy)carbonyl]amino}pentyl)(hydroxy)amino]-4-oxobutanoic acid	600-744-1	106410-46-2	-	View substance registered dossier
CBW Chemie GmbH Bitterfeld-Wolfen	Kühlturmstrasse 3 06803 Bitterfeld-Wolfen / OT Greppin Germany	Germany	Cease Manufacture	4-[(6-amino-1-hydroxy-3-sulpho-2-naphthyl)azo]-3-hydroxy-7-nitronaphthalene-1-sulphonic acid	204-203-7	117-69-1	2019	View substance registered dossier
URQUIMA S.A.	AVDA. CAMÍ REIAL, 51 -57 08184 PALAU-SOLITÀ I PLEGAMANS CATALUNYA Spain	Spain	Active	4-[(E)-2-nitroethenyl]-1H-indole	634-890-2	49839-99-8	-	View substance registered dossier
[Confidential]	-	-	-	4-[(EZ)-3-(3-Chloro-5-trifluoromethylphenyl)-4,4,4-trifluorobut-2-enoyl]-naphthalene-1-carboxylic acid [(2,2,2-trifluoroethylcarbamoyl)-methyl]amide	807-881-8	1125812-56-7	-	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	4-[2-((6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-ylsulfanyl)thiazole-4-yl]-1-methyl-pyridiniumchloride monohydrochloride	447-990-4	-	2019	View substance registered dossier
Eli Lilly Kinsale Limited	Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland	Ireland	Active	4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid	429-790-9	137281-39-1	2010; 2012; 2013; 2017	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	4-[2-(Cyclopropylmethoxy)ethyl]phenol	440-910-9	-	2017	View substance registered dossier
FINORGA - MOURENX	avenue du lac 64150 MOURENX France	France	Active	4-[2-(Cyclopropylmethoxy)ethyl]phenol	440-910-9	-	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	4-[2-(diethylamino)ethoxy]benzophenone	212-348-2	796-77-0	-	View substance registered dossier
Medichem Manufacturing (Malta) Limited	HF 61-Hal Far Industrial Estate BBG 3000 Hal Far Malta Malta	Malta	Active	4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol	700-516-2	93413-62-8	-	View substance registered dossier
Pfizer Ireland Pharmaceuticals	n/a P43 X336 Ringaskiddy Cork Ireland	Ireland	Active	4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol	700-516-2	93413-62-8	2013	View substance registered dossier
[Confidential]	-	-	-	4-[2-(methoxymethyl)-3-methyl-1-methylene-but-2-enyl]-1H-tetrazol-5-one	826-908-4	1472631-98-3	-	View substance registered dossier
QUIMICA SINTETICA, S.A.	C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain	Spain	Active	4-[2-[(phenylmethyl)amino]propyl]- Phenol	608-112-7	27566-05-8	-	View substance registered dossier
Archroma Germany GmbH	Kasteler Str. 45 65203 Wiesbaden Germany	Germany	Active	4-[2-[4-(2-benzoxazoleyl)phenyl]vinyl]benzoic acid	225-303-7	4763-79-5	2019	View substance registered dossier
Pfizer Ireland Pharmaceuticals	n/a P43 X336 Ringaskiddy Cork Ireland	Ireland	Active	4-[2-Ethoxy-5-(4-methyl-1-piperazinylsulfonyl)benzamido]-1-3-propyl-1H-pyrazole-5-carboxamide	639-263-7	200575-15-1	-	View substance registered dossier
Cambrex Profarmaco Milano Srl	via Curiel, 34 20067 Paullo MI Italy	Italy	Active	4-[2-piperidinoethoxy]benzoic acid hydrochloride	282-882-9	84449-80-9	-	View substance registered dossier
Eli Lilly Kinsale Limited	Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland	Ireland	Active	4-[2-piperidinoethoxy]benzoic acid hydrochloride	282-882-9	84449-80-9	-	View substance registered dossier
ERREGIERRE SPA	Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy	Italy	Active	4-[2-piperidinoethoxy]benzoic acid hydrochloride	282-882-9	84449-80-9	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	4-[2-piperidinoethoxy]benzoic acid hydrochloride	282-882-9	84449-80-9	2018	View substance registered dossier
Patheon Austria GmbH & Co KG	St. Peterstrasse 25 A-4020 Linz Austria	Austria	Active	4-[3-(2,5-Dichlor-4,6-dimethyl-1-oxido-3-pyridinyl)-1,2,4-oxadiazol-5-yl]-2-methoxy-6-nitrophenol	826-271-2	1402714-41-3	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	4-[3-(2,5-Dichlor-4,6-dimethyl-1-oxido-3-pyridinyl)-1,2,4-oxadiazol-5-yl]-2-methoxy-6-nitrophenol	826-271-2	1402714-41-3	2019	View substance registered dossier
FINORGA SAS	497 route de Givors 38670 CHASSE SUR RHONE France	France	Active	4-[3-iodo-1-(1-methylethyl)-1H-pyrazol-4-yl]-2-pyrimidinamine	826-700-3	1269440-54-1	2020	View substance registered dossier
SYNTESIA CHEMIE GmbH	Martinistr. 13 20251 Hamburg Germany	Germany	Active	4-[4-(4-aminophenyl)piperazin-1-yl]phenol	616-147-4	74853-08-0	-	View substance registered dossier
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Active	4-[4-(4-aminophenyl)piperazin-1-yl]phenol	616-147-4	74853-08-0	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Cease Manufacture	4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide hydrochloride	692-722-3	835621-07-3	2021	View substance registered dossier
EUROAPI Germany GmbH	Brüningstraße 50 65926 Frankfurt am Main Germany	Germany	Active	4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-α,α-dimethyl-ethyl ester benzeneacetic acid	616-391-1	76812-02-7	2022	View substance registered dossier
AGC Pharma Chemicals Europe, S.L.U.	Camí de la Pomereda, 13 08380 Malgrat de Mar (Barcelona) Spain	Spain	Active	4-[[(2-aminophenyl)methyl]amino]cyclohexyl acetate	298-842-9	93839-71-5	-	View substance registered dossier
Synthesia, a.s.	Semtín103 53002 Pardubice Czech Republic	Czech Republic	Active	4-[[2-chloro-5-(trifluoromethyl)phenyl]azo]-3-hydroxy-2-naphthoic acid	257-777-6	52238-94-5	2019	View substance registered dossier
Ferro Performance Pigments Belgium N.V.	Kortrijkstraat 153 8930 Menen Belgium	Belgium	Active	4-[[4-(dimethylamino)phenyl][4-(methylimino)cyclohexa-2,5-dien-1-ylidene]methyl]-N,N-dimethylaniline monohydrochloride	210-042-3	603-47-4	-	View substance registered dossier
PROCOS SpA	via Matteotti 249 28062 Cameri Piemonte Italy	Italy	Active	4-[bis(isopropyl)amino]-2,2-diphenylbutyronitrile	201-005-2	77-11-2	-	View substance registered dossier
ICROM S.r.l	Via delle arti, 33 20863 Concorezzo Italy	Italy	Active	4-acetamido-5-(ethylsulphonyl)-2-methoxybenzoic acid	302-772-7	94134-06-2	-	View substance registered dossier
Medichem S.A.	Polígon Industrial de Celrà 17460 Celrà Girona Spain	Spain	Active	4-acetamidobenzoic acid, compound with 1-(dimethylamino)propan-2-ol (1:1)	263-361-5	61990-51-0	-	View substance registered dossier
Clarochem Ireland Ltd	damastown mulhuddart dn 15 dublin Ireland	Ireland	Active	4-acetamidobenzoic acid, compound with 1-(dimethylamino)propan-2-ol (1:1)	263-361-5	61990-51-0	-	View substance registered dossier
ABC FARMACEUTICI Unibios Division	Via S. Pellico, 3 28069 TRECATE Italy	Italy	Active	4-acetamidobenzoic acid, compound with 1-(dimethylamino)propan-2-ol (1:1)	263-361-5	61990-51-0	2017	View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED（Changzhou Sunlight Pharmaceutical Co., Ltd.）	Regus Harcourt Centre D02 HW77 Dublin Ireland	Ireland	Active	4-acetamidobenzoic acid, compound with 1-(dimethylamino)propan-2-ol (1:1)	263-361-5	61990-51-0	-	View substance registered dossier
novasint-bauman s.r.l.	via vailate, 22 24040 calvenzano bergamo Italy	Italy	Active	4-acetamidobenzoic acid, compound with 1-(dimethylamino)propan-2-ol (1:1)	263-361-5	61990-51-0	-	View substance registered dossier
PHARMABEA s.r.l.	Via Volturno, 5 20900 Monza (MB) Italy	Italy	Active	4-acetamidobenzoic acid, compound with 1-(dimethylamino)propan-2-ol (1:1)	263-361-5	61990-51-0	-	View substance registered dossier
ICROM S.r.l	Via delle arti, 33 20863 Concorezzo Italy	Italy	Active	4-acetilammino-N-((1-etil-2pirrolidinil)metil) -5 etilsulfonil-2-metossi benzamide	925-003-2	-	-	View substance registered dossier
Saltigo GmbH	HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany	Germany	Active	4-acetyl-2-methylbenzoic acid	856-079-4	55860-35-0	-	View substance registered dossier
Syngenta Hellas Single Member S.A.C.I.	Anthousas Avenue 153 49 Anthousa - Attiki Greece	Greece	Active	4-acetyl-2-methylbenzoic acid	856-079-4	55860-35-0	-	View substance registered dossier
Saltigo GmbH	HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany	Germany	Active	4-Acetyl-2-methylbenzoyl chloride	870-641-6	1095275-05-0	-	View substance registered dossier
Saltigo GmbH	HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany	Germany	Active	4-acetyl-N-[(4R)-2-ethyl-3-oxo-1,2-oxazolidin-4-yl]-2-methylbenzamide	875-863-7	1309959-52-1	2022	View substance registered dossier
[Confidential]	-	-	-	4-acetyl-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]naphthalene-1-carboxamide	807-880-2	1125812-54-5	-	View substance registered dossier
Huvepharma Italia s.r.l.	Via Roberto Lepetit, 142 12075 GARESSIO (CN) Italy	Italy	Active	4-Acetylnaphthalene-1-carboxylic acid	807-884-4	131986-05-5	-	View substance registered dossier
sanofi chimie	82 avenue Raspail 94250 Gentilly France	France	Active	4-Acetylnaphthalene-1-carboxylic acid	807-884-4	131986-05-5	2017	View substance registered dossier
Symrise AG	Mühlenfeldstraße 1 37603 Holzminden Germany	Germany	Active	4-allylveratrole	202-223-0	93-15-2	2019	View substance registered dossier
ERNESTO VENTOS, S.A.	Carretera Reial 120B 08960 Sant Just Desvern Spain	Spain	Active	4-allylveratrole	202-223-0	93-15-2	2019	View substance registered dossier
Upjohn Manufacturing Ireland Unlimited	Little Island T45 F627 Co. Cork Ireland	Ireland	Active	4-amino-1-Methyl-3-n-propyl-5-pyrazolecarboxamide hydrochloride	938-723-7	-	2019; 2021	View substance registered dossier
Fermion Oy	Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland	Finland	Active	4-amino-10-methyl folic acid ethylester hydroiodide	617-385-1	82784-24-5	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 51373 Leverkusen Germany	Germany	Active	4-Amino-2,3-dichlorophenol	464-070-8	-	2010	View substance registered dossier
Saltigo GmbH	HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany	Germany	Active	4-Amino-2,3-dichlorophenol	464-070-8	-	2011; 2021	View substance registered dossier
KISCHEMICALS LLC	Gyártelep 3792 Sajóbábony Hungary	Hungary	Active	4-amino-2,4-dihydro-5-(1-methylethyl)-3H-1,2,4-triazol-3-one	689-404-1	96240-10-7	-	View substance registered dossier
Saltigo GmbH	HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany	Germany	Cease Manufacture	4-amino-2,4-dihydro-5-(1-methylethyl)-3H-1,2,4-triazol-3-one	689-404-1	96240-10-7	2017	View substance registered dossier
Heubach Colorants Germany GmbH	Brüningstrasse 50 65929 Frankfurt am Main Germany	Germany	Active	4-amino-2,5-dichloro-N,N-dimethylbenzenesulphonamide	247-501-2	26175-68-8	-	View substance registered dossier
Synthesia, a.s.	Semtín103 53002 Pardubice Czech Republic	Czech Republic	Active	4-amino-2,5-dichlorobenzenesulphonic acid	201-836-0	88-50-6	-	View substance registered dossier
REACH&Colours Kft	Petofi Sandor utca 11 I Em. 4 1052 Budapest Hungary	Hungary	Active	4-amino-2,5-dichlorobenzenesulphonic acid	201-836-0	88-50-6	2013	View substance registered dossier
AllessaProduktion GmbH	Alt-Fechenheim 34 60386 Frankfurt am Main Germany	Germany	Active	4-amino-2,5-dimethoxy-N-methylbenzenesulphonamide	256-435-3	49701-24-8	-	View substance registered dossier
Heubach Colorants Germany GmbH	Brüningstrasse 50 65929 Frankfurt am Main Germany	Germany	Active	4-amino-2,5-dimethoxy-N-methylbenzenesulphonamide	256-435-3	49701-24-8	-	View substance registered dossier
AllessaProduktion GmbH	Alt-Fechenheim 34 60386 Frankfurt am Main Germany	Germany	Cease Manufacture	4-amino-2,5-dimethoxy-N-phenylbenzenesulphonamide	257-821-4	52298-44-9	2019	View substance registered dossier
Heubach Colorants Germany GmbH	Brüningstrasse 50 65929 Frankfurt am Main Germany	Germany	Active	4-amino-2,5-dimethoxy-N-phenylbenzenesulphonamide	257-821-4	52298-44-9	-	View substance registered dossier
Synthon, s.r.o.	Brněnská 32 678 01 Blansko Czech Republic	Czech Republic	Active	4-amino-2-(trifluoromethyl)benzonitrile	700-293-1	654-70-6	-	View substance registered dossier
Fine Organics Limited	Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom	United Kingdom	No longer Valid	4-amino-2-(trifluoromethyl)benzonitrile	700-293-1	654-70-6	2021	View substance registered dossier
Biesterfeld Spezialchemie GmbH	Ferdinandstr. 41 20095 Hamburg Germany	Germany	Active	4-amino-2-(trifluoromethyl)benzonitrile	700-293-1	654-70-6	-	View substance registered dossier
ACETO GmbH	Hans-Henny-Jahnn-Weg 53 22085 Hamburg Germany	Germany	Active	4-amino-2-(trifluoromethyl)benzonitrile	700-293-1	654-70-6	-	View substance registered dossier
Flavine Europe GmbH	Wehrlestrasse 12 81679 Munich Germany	Germany	Active	4-amino-2-(trifluoromethyl)benzonitrile	700-293-1	654-70-6	2019	View substance registered dossier
[Confidential]	-	-	-	4-amino-2-chlorobenzonitrile	244-114-0	20925-27-3	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	4-Amino-2-fluoro-benzamide	809-434-2	609783-45-1	-	View substance registered dossier
[Confidential]	-	-	-	4-amino-2-methylpyrimidine-5-carbonitrile	211-814-2	698-29-3	-	View substance registered dossier
[Confidential]	-	-	-	4-amino-2-methylpyrimidine-5-methylamine	202-384-7	95-02-3	-	View substance registered dossier
sanofi chimie	82 avenue Raspail 94250 Gentilly France	France	Active	4-amino-3-(4-phenoxyphenyl)-1-[(3R)-piperidin-3-yl]-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one	954-509-6	1971921-35-3	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	4-amino-3-fluorophenol	402-230-0	399-95-1	-	View substance registered dossier
Pfizer Ireland Pharmaceuticals	n/a P43 X336 Ringaskiddy Cork Ireland	Ireland	Active	4-amino-3-hydroxybenzoic acid	629-073-2	2374-03-0	-	View substance registered dossier
Arran Chemical Company Ltd	Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland	Ireland	Active	4-amino-3-hydroxybenzoic acid	629-073-2	2374-03-0	-	View substance registered dossier
Synthesia, a.s.	Semtín103 53002 Pardubice Czech Republic	Czech Republic	Active	4-amino-3-nitrobenzenesulphonic acid	210-495-7	616-84-2	-	View substance registered dossier
ICROM S.r.l	Via delle arti, 33 20863 Concorezzo Italy	Italy	Active	4-amino-5-(ethylsulphonyl)-o-anisic acid	275-833-8	71675-87-1	-	View substance registered dossier
Cosma S.p.A.	Via Colleoni 15/17 24040 Ciserano (BG) Italy	Italy	Active	4-amino-5-(ethylsulphonyl)-o-anisic acid	275-833-8	71675-87-1	2018	View substance registered dossier
ICROM S.r.l	Via delle arti, 33 20863 Concorezzo Italy	Italy	Active	4-amino-5-(ethylthio)-o-anisic acid	275-832-2	71675-86-0	-	View substance registered dossier
Synthesia, a.s.	Semtín103 53002 Pardubice Czech Republic	Czech Republic	Active	4-amino-5-[(phenylsulphonyl)oxy]naphthalene-2,7-disulphonic acid	201-460-7	83-23-8	-	View substance registered dossier
FARMAK, a.s.	Na vlcinci 16/3 779 00 Olomouc Czech Republic	Czech Republic	Active	4-Amino-5-chloro-2,1,3-benzothiodiazole	457-490-8	-	2009; 2015	View substance registered dossier
Synthesia, a.s.	Semtín103 53002 Pardubice Czech Republic	Czech Republic	Active	4-amino-5-hydroxynaphthalene-2,7-disulphonic acid	201-975-7	90-20-0	-	View substance registered dossier
Heubach Colorants Germany GmbH	Brüningstrasse 50 65929 Frankfurt am Main Germany	Germany	Active	4-amino-5-methoxy-N,2-dimethylbenzenesulphonamide	256-380-5	49564-57-0	-	View substance registered dossier
AllessaProduktion GmbH	Alt-Fechenheim 34 60386 Frankfurt am Main Germany	Germany	Active	4-amino-5-methoxy-N,2-dimethylbenzenesulphonamide	256-380-5	49564-57-0	-	View substance registered dossier
MinAscent Leuna Production GmbH	Am Haupttor Gebäude 4208 06237 Leuna Germany	Germany	Active	4-amino-5-methylpyridin-2(1H)-one	682-818-3	95306-64-2	-	View substance registered dossier
Saltigo GmbH	HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany	Germany	Active	4-amino-5-methylpyridin-2(1H)-one	682-818-3	95306-64-2	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	4-amino-5-methylpyridin-2(1H)-one	682-818-3	95306-64-2	2016; 2019; 2020	View substance registered dossier
POLPHARMA	19 Pelplińska 83-200 Starogard Gdański Poland	Poland	Active	4-amino-6-chlorobenzene-1,3-disulphonamide	204-463-1	121-30-2	-	View substance registered dossier
Pliva Hrvatska doo	Prilaz baruna Filipovića 25 10000 Zagreb Croatia	Croatia	Active	4-amino-6-chlorobenzene-1,3-disulphonamide	204-463-1	121-30-2	-	View substance registered dossier
Cambrex Profarmaco Milano Srl	via Curiel, 34 20067 Paullo MI Italy	Italy	Active	4-amino-6-chlorobenzene-1,3-disulphonamide	204-463-1	121-30-2	-	View substance registered dossier
Ferro Performance Pigments Belgium N.V.	Kortrijkstraat 153 8930 Menen Belgium	Belgium	Active	4-amino-6-chlorotoluene-3-sulphonic acid	201-837-6	88-51-7	-	View substance registered dossier
Synthesia, a.s.	Semtín103 53002 Pardubice Czech Republic	Czech Republic	Active	4-amino-6-chlorotoluene-3-sulphonic acid	201-837-6	88-51-7	-	View substance registered dossier
Sun Chemical B.V.	Leeuwenveldseweg 3-t 1382 LV Weesp Netherlands	Netherlands	Active	4-amino-6-chlorotoluene-3-sulphonic acid	201-837-6	88-51-7	-	View substance registered dossier
Univar Solutions GmbH	Hinsbecker Löh 10c 45257 Essen Germany	Germany	Active	4-amino-6-chlorotoluene-3-sulphonic acid	201-837-6	88-51-7	-	View substance registered dossier
Sun Chemical A/S 7	Københavnsvej 112 4600 Køge Denmark	Denmark	Active	4-amino-6-chlorotoluene-3-sulphonic acid	201-837-6	88-51-7	-	View substance registered dossier
Heubach Colorants Germany GmbH	Brüningstrasse 50 65929 Frankfurt am Main Germany	Germany	Active	4-amino-6-chlorotoluene-3-sulphonic acid	201-837-6	88-51-7	-	View substance registered dossier
BASF plc	Earl Road, P O Box 4 SK8 6QG Cheadle Hulme Cheshire United Kingdom	United Kingdom	No longer Valid	4-amino-6-chlorotoluene-3-sulphonic acid	201-837-6	88-51-7	2021	View substance registered dossier
ORGANICA Feinchemie GmbH Wolfen	Ortsteil Wolfen Kunstseidestraße 5 06766 Bitterfeld-Wolfen Germany	Germany	Active	4-amino-N,N-diethylaniline	202-214-1	93-05-0	-	View substance registered dossier
Sun Chemical Colors & Effects GmbH	An der Rheinschanze 1 67059 Ludwigshafen Germany	Germany	Active	4-amino-N-(2-ethylhexyl)benzenesulphonamide	258-799-9	53817-09-7	-	View substance registered dossier
TOYO INK EUROPE SPECIALTY CHEMICALS	Boulevard Dambourney 76350 Oissel France	France	Active	4-amino-N-(2-methylquinolin-8-yl)benzenesulfonamide	700-562-3	909782-32-7	2015	View substance registered dossier
ARCHROMA IBÉRICA, S.L.	ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain	Spain	Active	4-amino-N-(4-amino-6-oxo-5H-pyrimidin-2-yl)benzenesulfonamide	605-738-2	174863-37-7	-	View substance registered dossier
URQUIMA S.A.	AVDA. CAMÍ REIAL, 51 -57 08184 PALAU-SOLITÀ I PLEGAMANS CATALUNYA Spain	Spain	Active	4-Amino-N-(terc-butyl)benzenesulfonamide	687-656-7	209917-48-6	-	View substance registered dossier
Clariant Produkte (Deutschland) GmbH	August-Laubenheimer-Straße 1 Global Product Stewardship 65929 Frankfurt am Main Germany	Germany	Cease Manufacture	4-Amino-N-[3-(diethylamino)propyl]benzamid, hydrochloride	814-672-5	109342-99-6	2022	View substance registered dossier
Heubach Colorants Germany GmbH	Brüningstrasse 50 65929 Frankfurt am Main Germany	Germany	Cease Manufacture	4-Amino-N-[3-(diethylamino)propyl]benzamid, hydrochloride	814-672-5	109342-99-6	2022	View substance registered dossier
TOYO INK EUROPE SPECIALTY CHEMICALS	Boulevard Dambourney 76350 Oissel France	France	Active	4-amino-N-[3-(diethylamino)propyl]benzamide	700-444-1	106595-73-7	-	View substance registered dossier
Synthesia, a.s.	Semtín103 53002 Pardubice Czech Republic	Czech Republic	Active	4-amino-N-[4-(aminocarbonyl)phenyl]benzamide	277-874-7	74441-06-8	-	View substance registered dossier
Heubach Colorants Germany GmbH	Brüningstrasse 50 65929 Frankfurt am Main Germany	Germany	Active	4-amino-N-[4-(aminocarbonyl)phenyl]benzamide	277-874-7	74441-06-8	-	View substance registered dossier
Sun Chemical Colors & Effects GmbH	An der Rheinschanze 1 67059 Ludwigshafen Germany	Germany	Active	4-aminoazobenzene	200-453-6	60-09-3	2015	View substance registered dossier
Bidachem S.p.A.	S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy	Italy	Cease Manufacture	4-Aminobenzoamidoxime	664-406-5	277319-62-7	2023	View substance registered dossier
AllessaProduktion GmbH	Alt-Fechenheim 34 60386 Frankfurt am Main Germany	Germany	Active	4-Aminobenzoamidoxime	664-406-5	277319-62-7	2016; 2017; 2019	View substance registered dossier
[Confidential]	-	-	-	4-aminobenzoic acid	205-753-0	150-13-0	-	View substance registered dossier
Biesterfeld Spezialchemie GmbH	Ferdinandstr. 41 20095 Hamburg Germany	Germany	Active	4-aminobenzonitrile	212-850-1	873-74-5	-	View substance registered dossier
Bidachem S.p.A.	S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy	Italy	Active	4-aminobenzonitrile	212-850-1	873-74-5	2019	View substance registered dossier
Bidachem S.p.A.	S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy	Italy	Active	4-aminomethyl-2-methoxyphenol hydrochloride	230-468-3	7149-10-2	-	View substance registered dossier
AromataGroup	Via Carolina Romani n. 35 20091 Bresso (MI) Italy	Italy	Active	4-aminonaphthalene-1-sulphonic acid	201-567-9	84-86-6	-	View substance registered dossier
[Confidential]	-	-	-	4-aminophenol	204-616-2	123-30-8	-	View substance registered dossier
CHEMI S.p.A.	Via dei lavoratori, 54 20092 Cinisello balsamo Lombardia Italy	Italy	Active	4-aminophenol	204-616-2	123-30-8	-	View substance registered dossier
Huvepharma Italia s.r.l.	Via Roberto Lepetit, 142 12075 GARESSIO (CN) Italy	Italy	Active	4-aminosalicylic acid	200-613-5	65-49-6	-	View substance registered dossier
JSC "Olainfarm"	Rupnicu str. 5 LV-2114 Olaine Latvia	Latvia	Active	4-aminosalicylic acid	200-613-5	65-49-6	-	View substance registered dossier
Synthesia, a.s.	Semtín103 53002 Pardubice Czech Republic	Czech Republic	Active	4-aminotoluene-2-sulphonanilide	201-221-7	79-72-1	-	View substance registered dossier
ARCHROMA IBÉRICA, S.L.	ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain	Spain	Active	4-anilinophenol	204-538-9	122-37-2	-	View substance registered dossier
DIPHARMA FRANCIS srl	Bissone, 5 20021 Baranzate Milano Italy	Italy	Active	4-azidobutan-1-amine; (7,7-dimethyl-3-oxo-4-bicyclo[2.2.1]heptanyl)methanesulfonic acid	943-084-2	-	-	View substance registered dossier
VALDEPHARM	Parc Industriel d'Incarville CS10606 27106 Val de Reuil France	France	Active	4-benzyl-1-(2-hydroxymethylphenyl)-2-phenylpiperazine-fumarate	700-842-5	1192015-20-5	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	4-benzyloxyaniline hydrochloride	257-170-6	51388-20-6	-	View substance registered dossier
Vynova PPC SAS	95 rue du Général de Gaulle BP 60090 68802 THANN CEDEX France	France	Active	4-bromo-1,2-dichlorobenzene	242-160-6	18282-59-2	2019	View substance registered dossier
ICL-IP Terneuzen B.V. (M)	Frankrijkweg 6, Havens/Docks 1205-45308 BJ 4538 BJ Terneuzen Netherlands	Netherlands	Active	4-bromo-1,2-dichlorobenzene	242-160-6	18282-59-2	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	4-bromo-1,2-dichlorobenzene	242-160-6	18282-59-2	2017	View substance registered dossier
Contract Chemicals Ltd	Penrhyn Road Knowsley Business Park L34 9HY Prescot Merseyside United Kingdom	United Kingdom	No longer Valid	4-bromo-1,2-dichlorobenzene	242-160-6	18282-59-2	2021	View substance registered dossier
B-Lands Consulting (811725-2)	5 Place Robert Schuman - BP 1516 38025 Grenoble France France	France	Active	4-bromo-1,2-dichlorobenzene	242-160-6	18282-59-2	-	View substance registered dossier
FINORGA SAS	497 route de Givors 38670 CHASSE SUR RHONE France	France	Active	4-Bromo-1-chloro-2-(4-ethoxy-benzyl)-benzene	636-921-5	461432-23-5	-	View substance registered dossier
Pfizer Ireland Pharmaceuticals	n/a P43 X336 Ringaskiddy Cork Ireland	Ireland	Active	4-bromo-1-chloro-2-[(4-éthoxyphenyl)(phenylmethoxy)-methyl]-benzene	807-813-7	1298086-15-3	-	View substance registered dossier
PCAS	21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France	France	Active	4-bromo-1-chloro-2-[(4-éthoxyphenyl)(phenylmethoxy)-methyl]-benzene	807-813-7	1298086-15-3	2021	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	4-bromo-2,3',4',5'-tetrafluoro-1,1'-biphenyl	936-926-5	-	-	View substance registered dossier
CENTIPHARM	Chemin de la Madeleine 06131 GRASSE FRANCE France	France	Cease Manufacture	4-bromo-2,6-difluorobenzoic acid	457-940-3	183065-68-1	2019	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Cease Manufacture	4-bromo-2,6-difluorobenzoic acid	457-940-3	183065-68-1	2019	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	4-Bromo-2,6-difluorobenzoyl chloride	803-879-6	497181-19-8	-	View substance registered dossier

Showing 8,401 - 8,500 of 26,865 results.

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
Link to the full factsheet.

Chemical Property Data Search

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

RELATED INFORMATION

Welcome to the REACH Registered Substance Factsheets

Here you will find details from REACH registrations submitted to ECHA. Registrations under REACH can be submitted either jointly – where a group of legal entities pool their data – or individually. The set of details from each published joint or individual submission is presented as a row in the results table. For each row there is also an ‘eye’ icon leading to the detailed factsheet which contains the entire public dataset, following the IUCLID format.

Note that there can be more than one joint or individual submission for the same substance, thus there can be cases where one substance is covered by many REACH registered substance factsheets.

Note too, that as mentioned in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission.

Finally, please note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

All substances table

The “All substances” table gives an overview of all the REACH registered substance factsheets on file at ECHA. Since this covers all data ever submitted since the entry into force of the REACH Regulation, there are some substances which are no longer considered registered under REACH in the EU / EEA. These can be for example substances that were registered only in the UK; since Brexit they are no longer registered in the EU / EEA.

The following columns are presented in the “All substances” table:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
‘Eye’ icon linking to the full factsheet.

Searching

The search for REACH registered substance factsheets is divided into logically separated blocks of related search filters. Note that the search works so that if you provide filters in different blocks, then the results returned must match the filters in block 1 AND those in block 2 etc. Searches are conducted on all the public data included in all published REACH registrations.

Substance identity

In this block you can search by substance identifiers, under filters for Name, EC / List number, and CAS number. Full or partial identifiers can be used. And under the Name filter you can search by any substance name of any kind from any source. Other numerical identifiers such as Harmonised C&L Index number, or PIC CN code can also optionally be used.

Administrative data

In this block you can search by administrative information relating to REACH registered substance factsheets:

Registration type – picklist of Full, Intermediate, NONS
Registration status – picklist of Active, Cease Manufacture, No longer valid
Submission type – Individual or Joint
Country in which registered – picklist of current and former EU / EEA member states from which REACH registrations were received
First published date – the date when a REACH registration factsheet was first published
Last update date – the last date when any registrant / supplier submission contributing to a given REACH registration factsheet was submitted
Last update year – the year in which any registrant / supplier last made an update submission included in a given REACH registration factsheet
Registrant / supplier name – where available and not claimed confidential
Registration number – where available and not claimed confidential
Registrant address – where available and not claimed confidential

Substance data

In this block you can search by substance related data from REACH registered substance factsheets:

Tonnage band – picklist of Tonnage range, Tonnage Confidential, Intermediate use only
Selected total tonnage band range – available only if Tonnage range is selected, and allows to filter REACH registered substance factsheets within any selected min and max value
Substance has nanoform – picklist of Yes, No
PBT assessment outcome – picklist of all possible PBT assessment outcomes
CSA performed – picklist of Yes, No

Use and exposure

In this block you can search by elements relating to how use and exposure are encoded in REACH registrations.

Under the Life cycle option you can select one or more life cycle stages. The search results returned will include only factsheets containing uses reported under the selected life cycle stages.

Under the Category option there are modal popups for each of the use descriptor categories – Product, Sector of use, Process, Environmental release, and Article categories. In each of these are multi select picklists for all the related descriptor codes. The search results returned will include only factsheets containing uses which include the selected descriptor codes.

Note that the Life cycle and Category options work together, so that if a life cycle stage and Category options are both selected the search results will include factsheets containing specific uses in the selected life cycle stage, and where the use includes the selected descriptor codes.

With the search operator option you can select to refine how the search works. AND refines results and returns only those factsheets where ALL the search filter criteria are met. OR broadens the results and returns factsheets where ANY of the selected search filter criteria are met.

The factsheets

There is always a detailed factsheet per joint or individual submission, and it is generated based primarily on the IUCLID format.

The factsheet header begins with the identity of the substance in question, to which the factsheet is linked. The substance identity should always be aligned with that shown in the related substance Infocard. Note that since the Infocard refreshes daily, whereas the factsheet sometimes refreshes on a slower pace, sometimes the data may be out of alignment. In such cases it will always realign as quickly as possible.

The substance identification is enriched with the data provided in the relevant IUCLID section of the primary submitted dossier – either the joint submission lead, or the single individual submission.

In this section are also provided the type of substance, all other identifiers such as trade names, common names, other names etc, as well as all distinct submitted compositions for the substance.

Next is a page covering administrative type information from the data submitted, including:

Registration details, on the total tonnage band informed to ECHA, the registration type, first published and last updated dates, and whether a chemical safety assessment has been performed.

Registrant / supplier details, giving the identity and status of registrants / suppliers, except where the identity has been claimed confidential.

Registration numbers, giving again the identity and status of registration numbers, except where claimed confidential.

Contact persons responsible for the SDS, giving the non-confidential SDS contacts provided to ECHA.

The remainder of the factsheet faithfully follows the IUCLID structure, covering the C&L and PBT, Manufacture, use, and exposure, Physical and chemical properties, Environmental fate and pathways, Ecotoxicological information, Toxicological information, Analytical methods (if available), Guidance on safe use, Assessment reports, and Reference substances.