Registered substances

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM. More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration

Showing 6,801 - 6,900 of 26,865 results.

Name	EC / List no.	CAS no.	Registration Status	Registration type	Submission type	Total tonnage band	Last Updated	Details
2-(methylsulphonyl)-10H-phenothiazine	245-701-4	23503-68-6	Active	Intermediate	Joint	Intermediate use only	31-05-2018	View substance registered dossier
2-(methylthio)-10H-phenothiazine	231-581-0	7643-08-5	Active	Intermediate	Joint	Intermediate use only	15-03-2018	View substance registered dossier
2-(methylthio)-5-(trifluoromethyl)-1,3,4-thiadiazole	807-656-4	32539-16-5	Cease Manufacture	Intermediate	Joint	Cease manufacture	26-11-2014	View substance registered dossier
2-(N-ethylanilino)ethyl-(2-hydroxypropyl)-dimethylazanium;sulfate	825-360-3	72269-47-7	Active	Intermediate	Joint	Intermediate use only	16-05-2018	View substance registered dossier
2-(N-methyl N-hydroxyethyl) ammine 2-phenylethanol	920-079-3	-	Active	Intermediate	Individual	Intermediate use only	16-01-2018	View substance registered dossier
2-(Naphthalene-2'-sulphonylamino)-benzoic acid	601-471-0	117309-52-1	Active	Intermediate	Joint	Intermediate use only	04-11-2019	View substance registered dossier
2-(octyloxy)benzoic acid	608-139-4	27830-12-2	Active	Intermediate	Joint	Intermediate use only	07-06-2016	View substance registered dossier
2-(octylthio)ethanol	222-598-4	3547-33-9	Active	Intermediate	Joint	Intermediate use only	28-11-2013	View substance registered dossier
2-(phenylmethylene)-1-Azabicyclo[2,2,2]octan-3-one	607-326-8	24123-89-5	Active	Intermediate	Joint	Intermediate use only	19-01-2018	View substance registered dossier
2-(piperazin-1-yl)pyrimidine	244-135-5	20980-22-7	Active	Intermediate	Joint	Intermediate use only	20-10-2021	View substance registered dossier
2-(piperidin-4-yl)-1H-1,3-benzodiazole	609-547-5	38385-95-4	Active	Intermediate	Joint	Intermediate use only	16-08-2021	View substance registered dossier
2-(ter-butylamino)-1-(3-chloro-4- hydroxyphenyl)ethanone HCl	918-208-3	-	Active	Intermediate	Joint	Intermediate use only	27-06-2016	View substance registered dossier
2-(Tert-Butoxycarbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid	866-813-5	851784-82-2	Active	Intermediate	Joint	Intermediate use only	14-04-2021	View substance registered dossier
2-(tert-butylamino)-1-(3-chloro-4-hydroxy-5-chloromethylphenyl)ethanone hydrochloride	930-857-4	-	Active	Intermediate	Joint	Intermediate use only	23-06-2016	View substance registered dossier
2-(tert-butylamino)acetic acid hydrochloride	614-959-3	6939-23-7	Active	Intermediate	Joint	Intermediate use only	14-12-2017	View substance registered dossier
2-(tert-butylamino)acetyl chloride hydrochloride	618-771-2	915725-52-9	Active	Intermediate	Joint	Intermediate use only	05-08-2019	View substance registered dossier
2-(thiophen-2-yl)phenol	826-707-1	106584-13-8	Cease Manufacture	Intermediate	Joint	Cease manufacture	10-10-2018	View substance registered dossier
2-(trifluoromethyl)-9H-thioxanthen-9-one	216-893-7	1693-28-3	Active	Intermediate	Individual	Intermediate use only	06-10-2020	View substance registered dossier
2-(trifluoromethyl)benzenesulfonamide	700-280-0	1869-24-5	Active	Intermediate	Joint	Intermediate use only	02-05-2017	View substance registered dossier
2-(trifluoromethyl)benzenesulfonyl chloride	700-328-0	776-04-5	Active	Intermediate	Joint	Intermediate use only	03-05-2017	View substance registered dossier
2-({2-[(3-aminobenzoyl)amino]ethyl}sulfonyl)ethyl hydrogen sulfate	601-770-6	121315-20-6	Cease Manufacture	Intermediate	Individual	Cease manufacture	25-02-2013	View substance registered dossier
2-({2-[4-(2,4,5-trimethylhexan-3-yl)phenoxy]ethoxy}methyl)oxirane	937-989-1	-	Cease Manufacture	Intermediate	Individual	Cease manufacture	23-05-2012	View substance registered dossier
2-({4-[(2-hexyldecyl)oxy]phenyl}sulfonyl)butanoyl chloride	700-365-2	-	Active	Intermediate	Individual	Intermediate use only	29-03-2010	View substance registered dossier
2-({6-[(3R)-3-Aminopiperidin-1-yl]-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl}methyl)benzonitrile hydrochloride	687-786-4	1246610-75-2	Active	Intermediate	Joint	Intermediate use only	31-10-2016	View substance registered dossier
2-({[(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl]oxy}methyl)oxirane	814-125-0	249297-16-3	Active	Intermediate	Joint	Intermediate use only	14-11-2017	View substance registered dossier
2-({[4-(3-methoxypropoxy)-3-methyl-1-oxidopyridin-2-yl]methyl}sulfanyl)-1H-benzimidazole	700-940-8	-	Active	Intermediate	Individual	Intermediate use only	12-02-2013	View substance registered dossier
2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-N,N-diethyl-1-phenyl-	921-437-1	-	Active	Intermediate	Joint	Intermediate use only	24-05-2018	View substance registered dossier
2-[(1R)-1-Amino-2-(2,5-dibromophenyl)ethyl]-5-bromophenol	813-147-8	1585969-24-9	Active	Intermediate	Individual	Intermediate use only	23-09-2016	View substance registered dossier
2-[(1R,4R,4aS,8aR)-4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl]prop-2-enoic acid	617-040-5	80286-58-4	Active	Intermediate	Joint	Intermediate use only	26-10-2012	View substance registered dossier
2-[(1S,2S,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-yl]ethanol	701-063-3	133001-09-9	Active	Intermediate	Joint	Intermediate use only	10-08-2020	View substance registered dossier
2-[(2-acetamido-6,9-dihydro-6-oxo-1H-purin-9-yl]methoxy]ethyl acetate	278-077-7	75128-73-3	Active	Intermediate	Joint	Intermediate use only	08-04-2022	View substance registered dossier
2-[(2-acetamido-6,9-dihydro-6-oxo-1H-purin-9-yl]methoxy]ethyl acetate	278-077-7	75128-73-3	Active	Intermediate	Joint	Intermediate use only	24-03-2023	View substance registered dossier
2-[(2-Acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]-1,3-propanediyl bis(4-methoxybenzoate)	949-341-5	-	Active	Intermediate	Individual	Intermediate use only	17-12-2018	View substance registered dossier
2-[(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy]ethyl N-[(benzyloxy)carbonyl]-L-valinate	424-810-2	-	Cease Manufacture	Intermediate	Joint	Cease manufacture	02-05-2012	View substance registered dossier
2-[(2-aminobenzoyl)amino]benzoic acid	210-304-7	612-34-0	Active	Intermediate	Joint	Intermediate use only	23-10-2019	View substance registered dossier
2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine	605-865-3	179687-79-7	Active	Intermediate	Individual	Intermediate use only	27-11-2014	View substance registered dossier
2-[(2-Hydroxyethyl)(methyl)amino]-1-phenyl-1-propanone	618-508-1	902267-47-4	Active	Intermediate	Joint	Intermediate use only	08-06-2016	View substance registered dossier
2-[(2-hydroxyethyl)(methyl)amino]-1-phenylpropan-1-ol	618-782-2	91688-17-4	Active	Intermediate	Joint	Intermediate use only	08-06-2016	View substance registered dossier
2-[(2-methylpropan-2-yl)oxy]ethyl methanesulfonate	815-321-9	235098-18-7	Active	Intermediate	Joint	Intermediate use only	17-02-2020	View substance registered dossier
2-[(2E)-2-(6-Methoxy-3,4-dihydronaphthalen-1(2H)-ylidene)ethyl]-2-methylcyclopentane-1,3-dione	618-321-5	899-79-6	Active	Intermediate	Joint	Intermediate use only	10-11-2015	View substance registered dossier
2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione	610-200-5	446292-07-5	Active	Intermediate	Individual	Intermediate use only	21-08-2018	View substance registered dossier
2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione	610-200-5	446292-07-5	Active	Intermediate	Joint	Intermediate use only	19-12-2022	View substance registered dossier
2-[(2S)-pyrrolidin-2-yl]-5-[4-(4-{2- [(2S)-pyrrolidin-2-yl]-1H-imidazol -5-yl}phenyl)phenyl]-1Himidazole tetrahydrochloride	807-342-7	1009119-83-8	Active	Intermediate	Joint	Intermediate use only	11-09-2017	View substance registered dossier
2-[(3-hydroxy-3-oxo-propanoyl)amino]benzoic acid	917-483-7	-	Active	Intermediate	Joint	Intermediate use only	17-02-2017	View substance registered dossier
2-[(3-methyl-4-nitropyridin-2-yl)methylsulfanyl]-1H-benzimidazole	460-440-8	-	Active	Intermediate	Individual	Intermediate use only	07-12-2011	View substance registered dossier
2-[(3-nitropyrazolo[1,5-a]pyridin-2-yl)oxy]ethanol	938-829-3	936103-10-5	Active	Intermediate	Joint	Intermediate use only	06-04-2022	View substance registered dossier
2-[(4-hydrazinophenyl)sulphonyl]ethanol	247-750-7	26505-12-4	Active	Intermediate	Joint	Intermediate use only	03-08-2018	View substance registered dossier
2-[(5-methyl-1H-1,2,4-triazol-3-yl)sulfanyl]acetic acid	813-419-6	64679-65-8	Active	Intermediate	Joint	Intermediate use only	19-01-2017	View substance registered dossier
2-[(6,11-Dihydro-5H-dibenz[b,e]azepin-6-yl)-methyl]-1H-isoindole-1,3(2H)-dione	629-841-7	143878-20-0	Active	Intermediate	Individual	Intermediate use only	31-10-2016	View substance registered dossier
2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide	695-686-7	302964-08-5	Active	Intermediate	Joint	Intermediate use only	11-09-2017	View substance registered dossier
2-[(6-Chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl]benzonitrile	695-742-0	865758-96-9	Active	Intermediate	Joint	Intermediate use only	14-12-2020	View substance registered dossier
2-[(acetyloxy)methoxy]ethyl acetate	261-686-7	59278-00-1	Active	Intermediate	Individual	Intermediate use only	31-05-2016	View substance registered dossier
2-[(acetyloxy)methoxy]ethyl acetate	261-686-7	59278-00-1	Cease Manufacture	Intermediate	Joint	Cease manufacture	10-05-2018	View substance registered dossier
2-[(but-3-yn-2-yloxy)carbonyl]benzoic acid	610-090-9	42969-62-0	Active	Intermediate	Joint	Intermediate use only	11-06-2020	View substance registered dossier
2-[(but-3-yn-2-yloxy)carbonyl]benzoic acid	610-090-9	42969-62-0	Active	Intermediate	Joint	Intermediate use only	10-10-2016	View substance registered dossier
2-[(C14-15alkyloxy)methyl]oxirane	700-630-2	-	Active	Intermediate	Individual	Intermediate use only	23-05-2012	View substance registered dossier
2-[(dichloroacetyl)amino]-3-hydroxy-3-[4-(methylsulphonyl)phenyl]propyl chloroacetate	284-235-6	84824-83-9	Active	Intermediate	Joint	Intermediate use only	27-04-2018	View substance registered dossier
2-[(dimethylamino)methyl]cyclohexan-1-one	239-422-7	15409-60-6	Active	Intermediate	Joint	Intermediate use only	25-05-2018	View substance registered dossier
2-[(E)-(6-Methyl-2,3,4,9-tetrahydro-1H-carbazol-1-ylidene)amino] ethanol	814-577-9	110951-48-9	Active	Intermediate	Joint	Intermediate use only	29-05-2017	View substance registered dossier
2-[(heptyloxy)methyl]oxirane	851-394-3	25717-59-3	Active	Intermediate	Joint	Intermediate use only	31-03-2020	View substance registered dossier
2-[(o-nitrophenyl)azo]-p-cresol	215-863-0	1435-71-8	Active	Intermediate	Individual	Intermediate use only	29-04-2010	View substance registered dossier
2-[(p-aminophenyl)sulphonyl]ethyl hydrogensulphate	219-669-7	2494-89-5	Active	Intermediate	Joint	Intermediate use only	19-01-2021	View substance registered dossier
2-[(Tetrahydro-2-furanyl)methyl]-propanedioic acid, 1,3-dimethyl ester	811-744-8	1134802-45-1	Cease Manufacture	Intermediate	Joint	Cease manufacture	15-03-2022	View substance registered dossier
2-[1-(2-{4-[2-(4,4-dimethyl-4,5-dihydro-1,3-oxazol-2-yl)propan-2-yl]phenyl}ethyl)piperidin-4-yl]-1-(2-ethoxyethyl)-1H-1,3-benzodiazole	813-963-4	202189-77-3	Active	Intermediate	Joint	Intermediate use only	23-12-2021	View substance registered dossier
2-[1-(2-{4-[2-(4,4-dimethyl-4,5-dihydro-1,3-oxazol-2-yl)propan-2-yl]phenyl}ethyl)piperidin-4-yl]-1H-1,3-benzodiazole	813-966-0	202189-81-9	Active	Intermediate	Joint	Intermediate use only	23-12-2021	View substance registered dossier
2-[1-(ethylsulfonyl)azetidin-3-ylidene]acetonitrile	691-838-1	1187595-85-2	Active	Intermediate	Joint	Intermediate use only	18-08-2020	View substance registered dossier
2-[2,4-bis(1,1-dimethylpropyl)phenoxy]butyryl chloride	254-978-0	40567-16-6	Active	Intermediate	Individual	Intermediate use only	27-04-2018	View substance registered dossier
2-[2,4-bis(tert-pentyl)phenoxy]butyric acid	236-495-7	13403-01-5	Active	Intermediate	Individual	Intermediate use only	27-04-2018	View substance registered dossier
2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2,4-triazolidine-3-thione	606-964-4	222408-90-4	Cease Manufacture	Intermediate	Individual	Cease manufacture	26-11-2010	View substance registered dossier
2-[2-(2,4-difluorophenyl)prop-2-en-1-yl]propane-1,3-diol	605-390-1	165115-73-1	Active	Intermediate	Individual	Intermediate use only	17-03-2021	View substance registered dossier
2-[2-(2-amino-6-chloro-9H-purin-9-yl)ethyl]propane-1,3-diol	923-654-7	-	No longer Valid	Intermediate	Joint	No longer valid	13-08-2014	View substance registered dossier
2-[2-(2-aminoethoxy)ethoxy]acetic acid;hydrochloride	816-400-0	134979-01-4	Active	Intermediate	Individual	Intermediate use only	16-09-2019	View substance registered dossier
2-[2-(2-aminoethoxy)ethylamino]ethanol	858-191-9	91598-32-2	Active	Intermediate	Joint	Intermediate use only	04-08-2020	View substance registered dossier
2-[2-(2-aminophenoxy)ethoxy]aniline	459-990-1	52411-34-4	Active	Intermediate	Joint	Intermediate use only	24-10-2013	View substance registered dossier
2-[2-(2-Carboxy-benzoylamino)-ethoxymethyl]-4-(2-chloro-phenyl)-6-methyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester	608-671-7	318465-73-5	Active	Intermediate	Joint	Intermediate use only	30-11-2020	View substance registered dossier
2-[2-(2-Fluorophenyl)-2-oxoethyl]propanedinitrile	807-718-0	312307-38-3	Active	Intermediate	Joint	Intermediate use only	17-09-2015	View substance registered dossier
2-[2-(2-phthalimidoethoxy)ethoxy]acetic acid	886-987-6	75001-09-1	Active	Intermediate	Individual	Intermediate use only	22-11-2022	View substance registered dossier
2-[2-(3,3-dimethyloxiranyl)vinyl]-2,3-dimethyloxirane	223-185-1	3765-28-4	No longer Valid	Intermediate	Joint	No longer valid	22-05-2018	View substance registered dossier
2-[2-(3,4-dihydro-6-methoxy-1(2H)-naphthylidene)ethyl]-2-ethylcyclopentane-1,3-dione	212-705-2	850-92-0	Active	Intermediate	Joint	Intermediate use only	24-02-2016	View substance registered dossier
2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide	603-107-6	125971-96-2	Active	Intermediate	Joint	Intermediate use only	20-09-2017	View substance registered dossier
2-[2-(6-Chloro-pyrimidin-4-yloxy)-phenyl]-3,3-dimethoxy-propionic acid methyl ester	604-340-6	143230-42-6	No longer Valid	Intermediate	Individual	No longer valid	11-12-2020	View substance registered dossier
2-[2-(diethylamino)ethoxy]ethanol	205-436-7	140-82-9	Active	Intermediate	Joint	Intermediate use only	17-12-2018	View substance registered dossier
2-[2-(dimethylamino)ethoxy]-N-methylethanamine	641-132-4	93240-93-8	Active	Intermediate	Joint	Intermediate use only	08-12-2021	View substance registered dossier
2-[2-(dimethylamino)ethyl]-2,3-dihydro-1H-inden-1-one	700-600-9	3409-21-0	Cease Manufacture	Intermediate	Joint	Cease manufacture	21-02-2017	View substance registered dossier
2-[2-(Methoxycarbonyl-phenyl-amino)-phenyl]-acetic acid	439-530-6	-	Active	Intermediate	Joint	Intermediate use only	24-04-2020	View substance registered dossier
2-[2-(Piperazin-1-yl)ethoxy]ethanol	700-022-7	13349-82-1	Active	Intermediate	Joint	Intermediate use only	18-01-2019	View substance registered dossier
2-[2-(Piperazin-1-yl)ethoxy]ethanol	700-022-7	13349-82-1	Active	Intermediate	Individual	Intermediate use only	16-03-2010	View substance registered dossier
2-[2-(piperidyl)ethoxy]ethanol	276-108-9	71872-99-6	Active	Intermediate	Joint	Intermediate use only	25-07-2018	View substance registered dossier
2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl methanesulfonate	700-859-8	477775-57-8	Active	Intermediate	Individual	Intermediate use only	03-06-2021	View substance registered dossier
2-[2-[2-[[2-[2-(2-aminoethoxy)ethoxy]acetyl]amino]ethoxy]ethoxy]acetic acid	815-071-0	1143516-05-5	Active	Intermediate	Individual	Intermediate use only	31-08-2017	View substance registered dossier
2-[2-[[1-(Ethoxycarbonyl)-3-phenylpropyl]-amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquimolinecarboxylic acid monohydrochloride, acetone solvate	919-408-3	-	Active	Intermediate	Individual	Intermediate use only	14-01-2020	View substance registered dossier
2-[2-oxopropyl]tetrahydro-2H-pyran-3,4,5-triol	610-159-3	439685-73-1	Active	Intermediate	Joint	Intermediate use only	30-04-2018	View substance registered dossier
2-[2-{4-[(4-aminobenzene)amido]-3-methoxyphenyl}diazen-1-yl]-6,8-bis[(sodiooxy)sulfonyl]naphthalen-1-yl	931-117-3	-	Active	Intermediate	Joint	Intermediate use only	09-11-2015	View substance registered dossier
2-[3,5-bis(trifluoromethyl)phenyl]-N-{4-(4-fluoro-2-methylphenyl)-6-[(7S,9aS)-7-(hydroxymethyl)hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]pyridin-3-yl}-N,2-dimethylpropanamide dihydrochloride isopropanol solvate	878-305-0	1268364-53-9	Active	Intermediate	Joint	Intermediate use only	29-04-2022	View substance registered dossier
2-[3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-methylphenol hydrochloride	811-311-3	124936-75-0	Active	Intermediate	Joint	Intermediate use only	19-11-2021	View substance registered dossier
2-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methylthio-1H-benzimidazole	600-451-9	103577-40-8	Active	Intermediate	Joint	Intermediate use only	27-01-2022	View substance registered dossier
2-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methylthio-1H-benzimidazole	600-451-9	103577-40-8	Cease Manufacture	Intermediate	Individual	Cease manufacture	04-10-2012	View substance registered dossier
2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]-N,N-diethylethanaminium bromide	936-979-4	-	Active	Intermediate	Joint	Intermediate use only	02-02-2022	View substance registered dossier
2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]-N,N-diethylethanaminium bromide	936-979-4	-	Active	Intermediate	Individual	Intermediate use only	12-11-2012	View substance registered dossier
2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropionic acid	255-626-9	42017-89-0	Active	Intermediate	Joint	Intermediate use only	22-11-2016	View substance registered dossier

Showing 6,801 - 6,900 of 26,865 results.

Registrant/Supplier	Address	Country	Registration Status	Name	EC / List no.	CAS no.	Last update year	Details
CENTIPHARM	Chemin de la Madeleine 06131 GRASSE FRANCE France	France	Active	2-(methylsulphonyl)-10H-phenothiazine	245-701-4	23503-68-6	-	View substance registered dossier
Trifarma S.p.A.	Via G. Guarini Matteucci 1 20162 Milan (MI) Italy	Italy	Active	2-(methylthio)-10H-phenothiazine	231-581-0	7643-08-5	-	View substance registered dossier
[Confidential]	-	-	-	2-(methylthio)-5-(trifluoromethyl)-1,3,4-thiadiazole	807-656-4	32539-16-5	-	View substance registered dossier
LEVACO Chemicals GmbH	CHEMPARK 51368 Leverkusen Germany	Germany	Active	2-(N-ethylanilino)ethyl-(2-hydroxypropyl)-dimethylazanium;sulfate	825-360-3	72269-47-7	-	View substance registered dossier
ARCHIMICA S.P.A.	Viale Milano 86 26900 Lodi Italy Italy	Italy	Active	2-(N-methyl N-hydroxyethyl) ammine 2-phenylethanol	920-079-3	-	2018	View substance registered dossier
Archroma Germany GmbH	Kasteler Str. 45 65203 Wiesbaden Germany	Germany	Active	2-(Naphthalene-2'-sulphonylamino)-benzoic acid	601-471-0	117309-52-1	2019	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	2-(octyloxy)benzoic acid	608-139-4	27830-12-2	2012; 2016	View substance registered dossier
Chevron Phillips Chemicals International NV	Airport Plaza, Stockholm Building, Da Vincilaan 19 B-1831 DIEGEM Belgium	Belgium	Active	2-(octylthio)ethanol	222-598-4	3547-33-9	2013	View substance registered dossier
INTEROR	49, rue d'Ostende F-62100 CALAIS France	France	Active	2-(phenylmethylene)-1-Azabicyclo[2,2,2]octan-3-one	607-326-8	24123-89-5	-	View substance registered dossier
LABORATORIOS SERVIER S.L.	RIO JARAMA 59 45007 TOLEDO Spain	Spain	Active	2-(piperazin-1-yl)pyrimidine	244-135-5	20980-22-7	-	View substance registered dossier
Fermion Oy	Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland	Finland	Active	2-(piperazin-1-yl)pyrimidine	244-135-5	20980-22-7	-	View substance registered dossier
PMC ISOCHEM	32 rue Lavoisier 91710 VERT LE PETIT France	France	Active	2-(piperazin-1-yl)pyrimidine	244-135-5	20980-22-7	-	View substance registered dossier
Biesterfeld Spezialchemie GmbH	Ferdinandstr. 41 20095 Hamburg Germany	Germany	Active	2-(piperazin-1-yl)pyrimidine	244-135-5	20980-22-7	2018	View substance registered dossier
ERREGIERRE SPA	Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy	Italy	Active	2-(piperazin-1-yl)pyrimidine	244-135-5	20980-22-7	-	View substance registered dossier
Faes Farma S.A.	Máximo Aguirre 14 48940 Leioa Vizcaya Spain	Spain	Active	2-(piperidin-4-yl)-1H-1,3-benzodiazole	609-547-5	38385-95-4	-	View substance registered dossier
SONEAS Chemicals Ltd.	Banyaleg Str. 47-59. H-1225 Budapest Hungary	Hungary	Active	2-(piperidin-4-yl)-1H-1,3-benzodiazole	609-547-5	38385-95-4	-	View substance registered dossier
Cambrex Profarmaco Milano Srl	via Curiel, 34 20067 Paullo MI Italy	Italy	Active	2-(ter-butylamino)-1-(3-chloro-4- hydroxyphenyl)ethanone HCl	918-208-3	-	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	2-(Tert-Butoxycarbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid	866-813-5	851784-82-2	-	View substance registered dossier
Cambrex Profarmaco Milano Srl	via Curiel, 34 20067 Paullo MI Italy	Italy	Active	2-(tert-butylamino)-1-(3-chloro-4-hydroxy-5-chloromethylphenyl)ethanone hydrochloride	930-857-4	-	-	View substance registered dossier
Pfizer Ireland Pharmaceuticals	n/a P43 X336 Ringaskiddy Cork Ireland	Ireland	Active	2-(tert-butylamino)acetic acid hydrochloride	614-959-3	6939-23-7	-	View substance registered dossier
Curia Italy S.r.l.	VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy	Italy	Active	2-(tert-butylamino)acetyl chloride hydrochloride	618-771-2	915725-52-9	-	View substance registered dossier
Pfizer Ireland Pharmaceuticals	n/a P43 X336 Ringaskiddy Cork Ireland	Ireland	Active	2-(tert-butylamino)acetyl chloride hydrochloride	618-771-2	915725-52-9	2013; 2018; 2019	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Cease Manufacture	2-(thiophen-2-yl)phenol	826-707-1	106584-13-8	2022	View substance registered dossier
H. Lundbeck A/S	Ottiliavej 7-9 2500 Copenhagen Denmark	Denmark	Active	2-(trifluoromethyl)-9H-thioxanthen-9-one	216-893-7	1693-28-3	-	View substance registered dossier
Derivados Químicos S.A.	Camino de Pliego, 150 30820 Alcantarilla Murcia Spain	Spain	Active	2-(trifluoromethyl)benzenesulfonamide	700-280-0	1869-24-5	2010; 2017	View substance registered dossier
[Confidential]	-	-	-	2-(trifluoromethyl)benzenesulfonamide	700-280-0	1869-24-5	-	View substance registered dossier
Derivados Químicos S.A.	Camino de Pliego, 150 30820 Alcantarilla Murcia Spain	Spain	Active	2-(trifluoromethyl)benzenesulfonyl chloride	700-328-0	776-04-5	2010; 2017	View substance registered dossier
Huntsman Textile Effects (Germany) GmbH	Rehlinger Str. 1 D-86462 Langweid a.Lech Germany	Germany	Cease Manufacture	2-({2-[(3-aminobenzoyl)amino]ethyl}sulfonyl)ethyl hydrogen sulfate	601-770-6	121315-20-6	2021	View substance registered dossier
Nouryon Surface Chemistry AB	Stenunge Allé 3 S-44485 Stenungsund Sweden	Sweden	Cease Manufacture	2-({2-[4-(2,4,5-trimethylhexan-3-yl)phenoxy]ethoxy}methyl)oxirane	937-989-1	-	2021	View substance registered dossier
La Mesta Bourgogne	Campus industriel Le Grand Chalon en Bourgogne Route de Demigny - BP21 71102 Chalon-sur-Saone France	France	Active	2-({4-[(2-hexyldecyl)oxy]phenyl}sulfonyl)butanoyl chloride	700-365-2	-	2010	View substance registered dossier
Takeda Ireland Limited	Bray Business Park Kilruddery N/A Bray Co. Wicklow Ireland	Ireland	Active	2-({6-[(3R)-3-Aminopiperidin-1-yl]-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl}methyl)benzonitrile hydrochloride	687-786-4	1246610-75-2	2016	View substance registered dossier
TAKASAGO TICSA-Producer/Importer	Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain	Spain	Active	2-({[(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl]oxy}methyl)oxirane	814-125-0	249297-16-3	-	View substance registered dossier
DIPHARMA FRANCIS srl	Bissone, 5 20021 Baranzate Milano Italy	Italy	Active	2-({[4-(3-methoxypropoxy)-3-methyl-1-oxidopyridin-2-yl]methyl}sulfanyl)-1H-benzimidazole	700-940-8	-	-	View substance registered dossier
PIERRE FABRE MEDICAMENT	Les Cauquillous 81500 LAVAUR France	France	Active	2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-N,N-diethyl-1-phenyl-	921-437-1	-	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	2-[(1R)-1-Amino-2-(2,5-dibromophenyl)ethyl]-5-bromophenol	813-147-8	1585969-24-9	-	View substance registered dossier
[Confidential]	-	-	-	2-[(1R,4R,4aS,8aR)-4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl]prop-2-enoic acid	617-040-5	80286-58-4	-	View substance registered dossier
TAKASAGO TICSA-Producer/Importer	Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain	Spain	Active	2-[(1S,2S,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-yl]ethanol	701-063-3	133001-09-9	-	View substance registered dossier
CU Chemie Uetikon GmbH	Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany	Germany	Active	2-[(1S,2S,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-yl]ethanol	701-063-3	133001-09-9	2017	View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES	30 rue Gambetta B.P. 206 40105 Dax Cedex France	France	Active	2-[(1S,2S,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-yl]ethanol	701-063-3	133001-09-9	-	View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A.	Mallorca 262 08008 Barcelona Barcelona Spain	Spain	Active	2-[(2-acetamido-6,9-dihydro-6-oxo-1H-purin-9-yl]methoxy]ethyl acetate	278-077-7	75128-73-3	2015; 2022	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	2-[(2-acetamido-6,9-dihydro-6-oxo-1H-purin-9-yl]methoxy]ethyl acetate	278-077-7	75128-73-3	2016	View substance registered dossier
Kemikos s.r.l.	Via Carolina Romani, 2/A 20091 Bresso (MI) Italy	Italy	Active	2-[(2-acetamido-6,9-dihydro-6-oxo-1H-purin-9-yl]methoxy]ethyl acetate	278-077-7	75128-73-3	-	View substance registered dossier
RECORDATI SPA	Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy	Italy	Active	2-[(2-acetamido-6,9-dihydro-6-oxo-1H-purin-9-yl]methoxy]ethyl acetate	278-077-7	75128-73-3	-	View substance registered dossier
Biesterfeld Spezialchemie GmbH	Ferdinandstr. 41 20095 Hamburg Germany	Germany	Active	2-[(2-acetamido-6,9-dihydro-6-oxo-1H-purin-9-yl]methoxy]ethyl acetate	278-077-7	75128-73-3	2022; 2023	View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l.	Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy	Italy	Active	2-[(2-acetamido-6,9-dihydro-6-oxo-1H-purin-9-yl]methoxy]ethyl acetate	278-077-7	75128-73-3	-	View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED	Room 002, Regus Harcourt Centre D02 HW77, Dublin, Ireland D02 Dublin Ireland	Ireland	Active	2-[(2-acetamido-6,9-dihydro-6-oxo-1H-purin-9-yl]methoxy]ethyl acetate	278-077-7	75128-73-3	-	View substance registered dossier
Excella GmbH & Co. KG	Nuernberger Str. 12 90537 Feucht Germany	Germany	Active	2-[(2-Acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]-1,3-propanediyl bis(4-methoxybenzoate)	949-341-5	-	-	View substance registered dossier
Thermofisher Scientific Cork Ltd.	Currabinny P43 AY66 Carrigaline Co. Cork Ireland	Ireland	Cease Manufacture	2-[(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy]ethyl N-[(benzyloxy)carbonyl]-L-valinate	424-810-2	-	2021	View substance registered dossier
Biesterfeld Spezialchemie GmbH	Ferdinandstr. 41 20095 Hamburg Germany	Germany	Active	2-[(2-aminobenzoyl)amino]benzoic acid	210-304-7	612-34-0	-	View substance registered dossier
Honeywell Specialty Chemicals Seelze GmbH	Wunstorfer Str. 40 30926 Seelze Deutschland Germany	Germany	Active	2-[(2-aminobenzoyl)amino]benzoic acid	210-304-7	612-34-0	-	View substance registered dossier
Első Vegyi Industria ZRt.	Kartács utca 6. H-1139 BUDAPEST Hungary	Hungary	Active	2-[(2-aminobenzoyl)amino]benzoic acid	210-304-7	612-34-0	-	View substance registered dossier
Esteve Quimica, S.A.	Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain	Spain	Active	2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine	605-865-3	179687-79-7	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	2-[(2-Hydroxyethyl)(methyl)amino]-1-phenyl-1-propanone	618-508-1	902267-47-4	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	2-[(2-hydroxyethyl)(methyl)amino]-1-phenylpropan-1-ol	618-782-2	91688-17-4	-	View substance registered dossier
[Confidential]	-	-	-	2-[(2-methylpropan-2-yl)oxy]ethyl methanesulfonate	815-321-9	235098-18-7	-	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	2-[(2E)-2-(6-Methoxy-3,4-dihydronaphthalen-1(2H)-ylidene)ethyl]-2-methylcyclopentane-1,3-dione	618-321-5	899-79-6	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 51373 Leverkusen Germany	Germany	Active	2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione	610-200-5	446292-07-5	2012; 2018	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione	610-200-5	446292-07-5	2012; 2018; 2022	View substance registered dossier
SK BIOTEK IRELAND LIMITED	Watery Lane Swords K67 AY91 Swords Co. Dublin Ireland	Ireland	Active	2-[(2S)-pyrrolidin-2-yl]-5-[4-(4-{2- [(2S)-pyrrolidin-2-yl]-1H-imidazol -5-yl}phenyl)phenyl]-1Himidazole tetrahydrochloride	807-342-7	1009119-83-8	-	View substance registered dossier
Swords Laboratories Unlimited Company	Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland	Ireland	Active	2-[(2S)-pyrrolidin-2-yl]-5-[4-(4-{2- [(2S)-pyrrolidin-2-yl]-1H-imidazol -5-yl}phenyl)phenyl]-1Himidazole tetrahydrochloride	807-342-7	1009119-83-8	2017	View substance registered dossier
Symrise AG	Mühlenfeldstraße 1 37603 Holzminden Germany	Germany	Active	2-[(3-hydroxy-3-oxo-propanoyl)amino]benzoic acid	917-483-7	-	-	View substance registered dossier
Amino Chemicals Ltd	Industrial Estate, A61 MRS3000 Marsa Malta	Malta	Active	2-[(3-methyl-4-nitropyridin-2-yl)methylsulfanyl]-1H-benzimidazole	460-440-8	-	-	View substance registered dossier
PMC ISOCHEM	32 rue Lavoisier 91710 VERT LE PETIT France	France	Active	2-[(3-nitropyrazolo[1,5-a]pyridin-2-yl)oxy]ethanol	938-829-3	936103-10-5	-	View substance registered dossier
[Confidential]	-	-	-	2-[(3-nitropyrazolo[1,5-a]pyridin-2-yl)oxy]ethanol	938-829-3	936103-10-5	-	View substance registered dossier
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Active	2-[(3-nitropyrazolo[1,5-a]pyridin-2-yl)oxy]ethanol	938-829-3	936103-10-5	2022	View substance registered dossier
Archroma Germany GmbH	Kasteler Str. 45 65203 Wiesbaden Germany	Germany	Active	2-[(4-hydrazinophenyl)sulphonyl]ethanol	247-750-7	26505-12-4	2018	View substance registered dossier
ERREGIERRE SPA	Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy	Italy	Active	2-[(5-methyl-1H-1,2,4-triazol-3-yl)sulfanyl]acetic acid	813-419-6	64679-65-8	-	View substance registered dossier
Biesterfeld Spezialchemie GmbH	Ferdinandstr. 41 20095 Hamburg Germany	Germany	Active	2-[(6,11-Dihydro-5H-dibenz[b,e]azepin-6-yl)-methyl]-1H-isoindole-1,3(2H)-dione	629-841-7	143878-20-0	-	View substance registered dossier
Swords Laboratories Unlimited Company	Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland	Ireland	Active	2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide	695-686-7	302964-08-5	2017	View substance registered dossier
SK BIOTEK IRELAND LIMITED	Watery Lane Swords K67 AY91 Swords Co. Dublin Ireland	Ireland	Active	2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide	695-686-7	302964-08-5	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	2-[(6-Chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl]benzonitrile	695-742-0	865758-96-9	-	View substance registered dossier
Takeda Ireland Limited	Bray Business Park Kilruddery N/A Bray Co. Wicklow Ireland	Ireland	Active	2-[(6-Chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl]benzonitrile	695-742-0	865758-96-9	-	View substance registered dossier
QUIMICA SINTETICA, S.A.	C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain	Spain	Active	2-[(acetyloxy)methoxy]ethyl acetate	261-686-7	59278-00-1	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Cease Manufacture	2-[(acetyloxy)methoxy]ethyl acetate	261-686-7	59278-00-1	2022	View substance registered dossier
Első Vegyi Industria ZRt.	Kartács utca 6. H-1139 BUDAPEST Hungary	Hungary	Active	2-[(but-3-yn-2-yloxy)carbonyl]benzoic acid	610-090-9	42969-62-0	-	View substance registered dossier
Výzkumný ústav organických syntéz a.s.	č.p. 296 533 54 Rybitví Czech Republic	Czech Republic	Active	2-[(but-3-yn-2-yloxy)carbonyl]benzoic acid	610-090-9	42969-62-0	-	View substance registered dossier
Nouryon Surface Chemistry AB	Stenunge Allé 3 S-44485 Stenungsund Sweden	Sweden	Active	2-[(C14-15alkyloxy)methyl]oxirane	700-630-2	-	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	2-[(dichloroacetyl)amino]-3-hydroxy-3-[4-(methylsulphonyl)phenyl]propyl chloroacetate	284-235-6	84824-83-9	-	View substance registered dossier
Saneca Pharmaceuticals a.s.	Nitrianska 100 92027 Hlohovec Slovakia	Slovakia	Active	2-[(dimethylamino)methyl]cyclohexan-1-one	239-422-7	15409-60-6	-	View substance registered dossier
ERREGIERRE SPA	Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy	Italy	Active	2-[(E)-(6-Methyl-2,3,4,9-tetrahydro-1H-carbazol-1-ylidene)amino] ethanol	814-577-9	110951-48-9	-	View substance registered dossier
Sachem Europe BV	Van Voordenpark 15 5301 KP Zaltbommel Gelderland Netherlands	Netherlands	Active	2-[(heptyloxy)methyl]oxirane	851-394-3	25717-59-3	-	View substance registered dossier
BASF Lampertheim GmbH	Chemiestrasse 22 68619 Lampertheim Germany	Germany	Active	2-[(o-nitrophenyl)azo]-p-cresol	215-863-0	1435-71-8	-	View substance registered dossier
DyStar Colours Distribution GmbH	Am Prime-Parc 12 65479 Raunheim Germany	Germany	Cease Manufacture	2-[(p-aminophenyl)sulphonyl]ethyl hydrogensulphate	219-669-7	2494-89-5	2021	View substance registered dossier
BLENDWELL SA	rue Benoît, 50 Zoning Industriel B-7370 Dour Belgium	Belgium	Active	2-[(p-aminophenyl)sulphonyl]ethyl hydrogensulphate	219-669-7	2494-89-5	2021	View substance registered dossier
Merck Santé s.a.s.	37, rue Saint Romain TSA 40123 69379 LYON CEDEX France	France	Cease Manufacture	2-[(Tetrahydro-2-furanyl)methyl]-propanedioic acid, 1,3-dimethyl ester	811-744-8	1134802-45-1	2022	View substance registered dossier
Faes Farma S.A.	Máximo Aguirre 14 48940 Leioa Vizcaya Spain	Spain	Active	2-[1-(2-{4-[2-(4,4-dimethyl-4,5-dihydro-1,3-oxazol-2-yl)propan-2-yl]phenyl}ethyl)piperidin-4-yl]-1-(2-ethoxyethyl)-1H-1,3-benzodiazole	813-963-4	202189-77-3	-	View substance registered dossier
URQUIMA S.A.	AVDA. CAMÍ REIAL, 51 -57 08184 PALAU-SOLITÀ I PLEGAMANS CATALUNYA Spain	Spain	Active	2-[1-(2-{4-[2-(4,4-dimethyl-4,5-dihydro-1,3-oxazol-2-yl)propan-2-yl]phenyl}ethyl)piperidin-4-yl]-1-(2-ethoxyethyl)-1H-1,3-benzodiazole	813-963-4	202189-77-3	2021	View substance registered dossier
URQUIMA S.A.	AVDA. CAMÍ REIAL, 51 -57 08184 PALAU-SOLITÀ I PLEGAMANS CATALUNYA Spain	Spain	Active	2-[1-(2-{4-[2-(4,4-dimethyl-4,5-dihydro-1,3-oxazol-2-yl)propan-2-yl]phenyl}ethyl)piperidin-4-yl]-1H-1,3-benzodiazole	813-966-0	202189-81-9	2021	View substance registered dossier
Faes Farma S.A.	Máximo Aguirre 14 48940 Leioa Vizcaya Spain	Spain	Active	2-[1-(2-{4-[2-(4,4-dimethyl-4,5-dihydro-1,3-oxazol-2-yl)propan-2-yl]phenyl}ethyl)piperidin-4-yl]-1H-1,3-benzodiazole	813-966-0	202189-81-9	-	View substance registered dossier
Eli Lilly Kinsale Limited	Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland	Ireland	Active	2-[1-(ethylsulfonyl)azetidin-3-ylidene]acetonitrile	691-838-1	1187595-85-2	-	View substance registered dossier
LA MESTA CHIMIE FINE	1336 Route de l'Estéron 06830 GILETTE France	France	Active	2-[2,4-bis(1,1-dimethylpropyl)phenoxy]butyryl chloride	254-978-0	40567-16-6	-	View substance registered dossier
LA MESTA CHIMIE FINE	1336 Route de l'Estéron 06830 GILETTE France	France	Active	2-[2,4-bis(tert-pentyl)phenoxy]butyric acid	236-495-7	13403-01-5	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Cease Manufacture	2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2,4-triazolidine-3-thione	606-964-4	222408-90-4	2023	View substance registered dossier
MinAscent Leuna Production GmbH	Am Haupttor Gebäude 4208 06237 Leuna Germany	Germany	Active	2-[2-(2,4-difluorophenyl)prop-2-en-1-yl]propane-1,3-diol	605-390-1	165115-73-1	2020; 2021	View substance registered dossier
Novartis Grimsby Limited	Moody Lane, Pyewipe DN31 2SR Grimsby N.E. Lincolnshire United Kingdom	United Kingdom	No longer Valid	2-[2-(2-amino-6-chloro-9H-purin-9-yl)ethyl]propane-1,3-diol	923-654-7	-	2021	View substance registered dossier
Flamma S.p.a.	via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy	Italy	Active	2-[2-(2-aminoethoxy)ethoxy]acetic acid;hydrochloride	816-400-0	134979-01-4	2019	View substance registered dossier
HUNTSMAN HOLLAND BV	Merseyweg 10 3197 KG Botlek-Rotterdam Netherlands	Netherlands	Active	2-[2-(2-aminoethoxy)ethylamino]ethanol	858-191-9	91598-32-2	-	View substance registered dossier
Ferro Performance Pigments Belgium N.V.	Kortrijkstraat 153 8930 Menen Belgium	Belgium	Active	2-[2-(2-aminophenoxy)ethoxy]aniline	459-990-1	52411-34-4	-	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	2-[2-(2-Carboxy-benzoylamino)-ethoxymethyl]-4-(2-chloro-phenyl)-6-methyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester	608-671-7	318465-73-5	2020	View substance registered dossier
Takeda Ireland Limited	Bray Business Park Kilruddery N/A Bray Co. Wicklow Ireland	Ireland	Active	2-[2-(2-Fluorophenyl)-2-oxoethyl]propanedinitrile	807-718-0	312307-38-3	-	View substance registered dossier
Flamma S.p.a.	via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy	Italy	Active	2-[2-(2-phthalimidoethoxy)ethoxy]acetic acid	886-987-6	75001-09-1	-	View substance registered dossier
Emerald Kalama Chemical Limited	Dans Road WA8 0RF Widnes Cheshire United Kingdom	United Kingdom	No longer Valid	2-[2-(3,3-dimethyloxiranyl)vinyl]-2,3-dimethyloxirane	223-185-1	3765-28-4	2021	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	2-[2-(3,4-dihydro-6-methoxy-1(2H)-naphthylidene)ethyl]-2-ethylcyclopentane-1,3-dione	212-705-2	850-92-0	2016	View substance registered dossier
Krka, d. d., Novo mesto	Smarjeska cesta 6 SI-8501 Novo mesto Slovenia	Slovenia	Active	2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide	603-107-6	125971-96-2	-	View substance registered dossier
Syngenta Ltd	Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom	United Kingdom	No longer Valid	2-[2-(6-Chloro-pyrimidin-4-yloxy)-phenyl]-3,3-dimethoxy-propionic acid methyl ester	604-340-6	143230-42-6	2021	View substance registered dossier
Midas Pharma Polska Sp. z o.o.	Ul. Hankiewicza 2 02-103 Warszawa Poland	Poland	Active	2-[2-(diethylamino)ethoxy]ethanol	205-436-7	140-82-9	-	View substance registered dossier
FARMAK, a.s.	Na vlcinci 16/3 779 00 Olomouc Czech Republic	Czech Republic	Active	2-[2-(diethylamino)ethoxy]ethanol	205-436-7	140-82-9	2018	View substance registered dossier
CU Chemie Uetikon GmbH	Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany	Germany	Active	2-[2-(diethylamino)ethoxy]ethanol	205-436-7	140-82-9	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	2-[2-(diethylamino)ethoxy]ethanol	205-436-7	140-82-9	2017	View substance registered dossier
[Confidential]	-	-	-	2-[2-(dimethylamino)ethoxy]-N-methylethanamine	641-132-4	93240-93-8	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Cease Manufacture	2-[2-(dimethylamino)ethyl]-2,3-dihydro-1H-inden-1-one	700-600-9	3409-21-0	2022	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	2-[2-(Methoxycarbonyl-phenyl-amino)-phenyl]-acetic acid	439-530-6	-	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	2-[2-(Piperazin-1-yl)ethoxy]ethanol	700-022-7	13349-82-1	-	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Cease Manufacture	2-[2-(Piperazin-1-yl)ethoxy]ethanol	700-022-7	13349-82-1	2020	View substance registered dossier
Medichem S.A.	Polígon Industrial de Celrà 17460 Celrà Girona Spain	Spain	Active	2-[2-(Piperazin-1-yl)ethoxy]ethanol	700-022-7	13349-82-1	-	View substance registered dossier
Fermion Oy	Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland	Finland	Active	2-[2-(Piperazin-1-yl)ethoxy]ethanol	700-022-7	13349-82-1	2009; 2014; 2019	View substance registered dossier
Medichem Manufacturing (Malta) Limited	HF 61-Hal Far Industrial Estate BBG 3000 Hal Far Malta Malta	Malta	Active	2-[2-(Piperazin-1-yl)ethoxy]ethanol	700-022-7	13349-82-1	2011; 2018	View substance registered dossier
MOEHS CANTABRA	P.I.Requejada Z-23 39313 Polanco Cantabria Spain	Spain	Active	2-[2-(Piperazin-1-yl)ethoxy]ethanol	700-022-7	13349-82-1	-	View substance registered dossier
Menadiona SL	Pol Ind Mas Puigvert, Ctra Nacional II Km 680, 5 08389 Palafolls Barcelona Spain	Spain	Active	2-[2-(Piperazin-1-yl)ethoxy]ethanol	700-022-7	13349-82-1	-	View substance registered dossier
Chemsafe	Via Ribes 5 10010 Colleretto Giacosa (TO) Italy	Italy	Active	2-[2-(Piperazin-1-yl)ethoxy]ethanol	700-022-7	13349-82-1	-	View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A.	Mallorca 262 08008 Barcelona Barcelona Spain	Spain	Active	2-[2-(Piperazin-1-yl)ethoxy]ethanol	700-022-7	13349-82-1	-	View substance registered dossier
PMC ISOCHEM	32 rue Lavoisier 91710 VERT LE PETIT France	France	Active	2-[2-(piperidyl)ethoxy]ethanol	276-108-9	71872-99-6	-	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Active	2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl methanesulfonate	700-859-8	477775-57-8	2021	View substance registered dossier
Flamma S.p.a.	via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy	Italy	Active	2-[2-[2-[[2-[2-(2-aminoethoxy)ethoxy]acetyl]amino]ethoxy]ethoxy]acetic acid	815-071-0	1143516-05-5	-	View substance registered dossier
[Confidential]	-	-	-	2-[2-[[1-(Ethoxycarbonyl)-3-phenylpropyl]-amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquimolinecarboxylic acid monohydrochloride, acetone solvate	919-408-3	-	-	View substance registered dossier
PMC ISOCHEM	32 rue Lavoisier 91710 VERT LE PETIT France	France	Active	2-[2-oxopropyl]tetrahydro-2H-pyran-3,4,5-triol	610-159-3	439685-73-1	-	View substance registered dossier
NOVEAL	16 rue Maurice Berteaux 95500 LE THILLAY France	France	Active	2-[2-oxopropyl]tetrahydro-2H-pyran-3,4,5-triol	610-159-3	439685-73-1	-	View substance registered dossier
ARCHROMA IBÉRICA, S.L.	ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain	Spain	Active	2-[2-{4-[(4-aminobenzene)amido]-3-methoxyphenyl}diazen-1-yl]-6,8-bis[(sodiooxy)sulfonyl]naphthalen-1-yl	931-117-3	-	2015	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	2-[3,5-bis(trifluoromethyl)phenyl]-N-{4-(4-fluoro-2-methylphenyl)-6-[(7S,9aS)-7-(hydroxymethyl)hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]pyridin-3-yl}-N,2-dimethylpropanamide dihydrochloride isopropanol solvate	878-305-0	1268364-53-9	-	View substance registered dossier
Upjohn Manufacturing Ireland Unlimited	Little Island T45 F627 Co. Cork Ireland	Ireland	Active	2-[3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-methylphenol hydrochloride	811-311-3	124936-75-0	2019; 2021	View substance registered dossier
Pfizer Ireland Pharmaceuticals	n/a P43 X336 Ringaskiddy Cork Ireland	Ireland	Active	2-[3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-methylphenol hydrochloride	811-311-3	124936-75-0	-	View substance registered dossier
DIPHARMA FRANCIS srl	Bissone, 5 20021 Baranzate Milano Italy	Italy	Active	2-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methylthio-1H-benzimidazole	600-451-9	103577-40-8	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	2-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methylthio-1H-benzimidazole	600-451-9	103577-40-8	-	View substance registered dossier
RECORDATI SPA	Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy	Italy	Active	2-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methylthio-1H-benzimidazole	600-451-9	103577-40-8	-	View substance registered dossier
Esteve Quimica, S.A.	Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain	Spain	Cease Manufacture	2-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methylthio-1H-benzimidazole	600-451-9	103577-40-8	2017	View substance registered dossier
PCAS	21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France	France	Active	2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]-N,N-diethylethanaminium bromide	936-979-4	-	2013; 2022	View substance registered dossier
Excella GmbH & Co. KG	Nuernberger Str. 12 90537 Feucht Germany	Germany	Active	2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]-N,N-diethylethanaminium bromide	936-979-4	-	2012	View substance registered dossier
Derivados Químicos S.A.	Camino de Pliego, 150 30820 Alcantarilla Murcia Spain	Spain	Active	2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropionic acid	255-626-9	42017-89-0	-	View substance registered dossier

Showing 6,801 - 6,900 of 26,865 results.

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
Link to the full factsheet.

Chemical Property Data Search

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

RELATED INFORMATION

Welcome to the REACH Registered Substance Factsheets

Here you will find details from REACH registrations submitted to ECHA. Registrations under REACH can be submitted either jointly – where a group of legal entities pool their data – or individually. The set of details from each published joint or individual submission is presented as a row in the results table. For each row there is also an ‘eye’ icon leading to the detailed factsheet which contains the entire public dataset, following the IUCLID format.

Note that there can be more than one joint or individual submission for the same substance, thus there can be cases where one substance is covered by many REACH registered substance factsheets.

Note too, that as mentioned in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission.

Finally, please note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

All substances table

The “All substances” table gives an overview of all the REACH registered substance factsheets on file at ECHA. Since this covers all data ever submitted since the entry into force of the REACH Regulation, there are some substances which are no longer considered registered under REACH in the EU / EEA. These can be for example substances that were registered only in the UK; since Brexit they are no longer registered in the EU / EEA.

The following columns are presented in the “All substances” table:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
‘Eye’ icon linking to the full factsheet.

Searching

The search for REACH registered substance factsheets is divided into logically separated blocks of related search filters. Note that the search works so that if you provide filters in different blocks, then the results returned must match the filters in block 1 AND those in block 2 etc. Searches are conducted on all the public data included in all published REACH registrations.

Substance identity

In this block you can search by substance identifiers, under filters for Name, EC / List number, and CAS number. Full or partial identifiers can be used. And under the Name filter you can search by any substance name of any kind from any source. Other numerical identifiers such as Harmonised C&L Index number, or PIC CN code can also optionally be used.

Administrative data

In this block you can search by administrative information relating to REACH registered substance factsheets:

Registration type – picklist of Full, Intermediate, NONS
Registration status – picklist of Active, Cease Manufacture, No longer valid
Submission type – Individual or Joint
Country in which registered – picklist of current and former EU / EEA member states from which REACH registrations were received
First published date – the date when a REACH registration factsheet was first published
Last update date – the last date when any registrant / supplier submission contributing to a given REACH registration factsheet was submitted
Last update year – the year in which any registrant / supplier last made an update submission included in a given REACH registration factsheet
Registrant / supplier name – where available and not claimed confidential
Registration number – where available and not claimed confidential
Registrant address – where available and not claimed confidential

Substance data

In this block you can search by substance related data from REACH registered substance factsheets:

Tonnage band – picklist of Tonnage range, Tonnage Confidential, Intermediate use only
Selected total tonnage band range – available only if Tonnage range is selected, and allows to filter REACH registered substance factsheets within any selected min and max value
Substance has nanoform – picklist of Yes, No
PBT assessment outcome – picklist of all possible PBT assessment outcomes
CSA performed – picklist of Yes, No

Use and exposure

In this block you can search by elements relating to how use and exposure are encoded in REACH registrations.

Under the Life cycle option you can select one or more life cycle stages. The search results returned will include only factsheets containing uses reported under the selected life cycle stages.

Under the Category option there are modal popups for each of the use descriptor categories – Product, Sector of use, Process, Environmental release, and Article categories. In each of these are multi select picklists for all the related descriptor codes. The search results returned will include only factsheets containing uses which include the selected descriptor codes.

Note that the Life cycle and Category options work together, so that if a life cycle stage and Category options are both selected the search results will include factsheets containing specific uses in the selected life cycle stage, and where the use includes the selected descriptor codes.

With the search operator option you can select to refine how the search works. AND refines results and returns only those factsheets where ALL the search filter criteria are met. OR broadens the results and returns factsheets where ANY of the selected search filter criteria are met.

The factsheets

There is always a detailed factsheet per joint or individual submission, and it is generated based primarily on the IUCLID format.

The factsheet header begins with the identity of the substance in question, to which the factsheet is linked. The substance identity should always be aligned with that shown in the related substance Infocard. Note that since the Infocard refreshes daily, whereas the factsheet sometimes refreshes on a slower pace, sometimes the data may be out of alignment. In such cases it will always realign as quickly as possible.

The substance identification is enriched with the data provided in the relevant IUCLID section of the primary submitted dossier – either the joint submission lead, or the single individual submission.

In this section are also provided the type of substance, all other identifiers such as trade names, common names, other names etc, as well as all distinct submitted compositions for the substance.

Next is a page covering administrative type information from the data submitted, including:

Registration details, on the total tonnage band informed to ECHA, the registration type, first published and last updated dates, and whether a chemical safety assessment has been performed.

Registrant / supplier details, giving the identity and status of registrants / suppliers, except where the identity has been claimed confidential.

Registration numbers, giving again the identity and status of registration numbers, except where claimed confidential.

Contact persons responsible for the SDS, giving the non-confidential SDS contacts provided to ECHA.

The remainder of the factsheet faithfully follows the IUCLID structure, covering the C&L and PBT, Manufacture, use, and exposure, Physical and chemical properties, Environmental fate and pathways, Ecotoxicological information, Toxicological information, Analytical methods (if available), Guidance on safe use, Assessment reports, and Reference substances.