Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
(2S)-2-hydroxy-1-(1-pyrrolidinyl)-1-propanone
601-833-8 122151-38-6 Active Intermediate Individual Intermediate use only 24-01-2018 View substance registered dossier
(2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanonone
477-290-4 - Active NONS Joint Tonnage data confidential 01-03-2013 View substance registered dossier
(2S)-4-amino-2-hydroxy-butanoic acid
670-305-7 40371-51-5 Active Intermediate Individual Intermediate use only 27-01-2020 View substance registered dossier
(2S)-5-(benzyloxy)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-5-oxopentanoic acid
443-560-5 88784-33-2 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(2S)-5-amino-2-[(aminoacetyl)amino]-5-oxopentanoic acid
700-144-0 13115-71-4 Active Full Individual ≥ 1 to < 10 tonnes 25-02-2010 View substance registered dossier
(2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride (1:1)
695-797-0 93601-86-6 Cease Manufacture Full Joint Cease manufacture 04-07-2018 View substance registered dossier
(2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride (1:1)
695-797-0 93601-86-6 Active Intermediate Joint Intermediate use only 13-11-2018 View substance registered dossier
(2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-aminium (2R)-(2-chlorophenyl)(hydroxy)acetate
814-350-4 1352917-66-8 Cease Manufacture Full Joint Cease manufacture 04-07-2018 View substance registered dossier
(2S)-but-3-yn-2-yl methanesulfonate
857-677-8 73647-37-7 Active Intermediate Individual Intermediate use only 24-07-2020 View substance registered dossier
(2S)-N-(2,6-dimethylphenyl)-1-propyl-piperidine-2-carboxamide
617-525-1 84057-95-4 Active Intermediate Individual Intermediate use only 11-10-2017 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active (2S)-2-hydroxy-1-(1-pyrrolidinyl)-1-propanone 601-833-8 122151-38-6 - View substance registered dossier
Első Vegyi Industria ZRt. Kartács utca 6. H-1139 BUDAPEST Hungary Hungary Active (2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanonone 477-290-4 - - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanonone 477-290-4 - 2019 View substance registered dossier
Gruenenthal GmbH Zieglerstrasse 6 52078 Aachen Germany Germany Active (2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanonone 477-290-4 - - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active (2S)-4-amino-2-hydroxy-butanoic acid 670-305-7 40371-51-5 - View substance registered dossier
ISOCHEM 32 rue Lavoisier 91710 VERT LE PETIT France France Active (2S)-5-(benzyloxy)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-5-oxopentanoic acid 443-560-5 88784-33-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active (2S)-5-(benzyloxy)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-5-oxopentanoic acid 443-560-5 88784-33-2 - View substance registered dossier
Evonik Rexim S.A.S. 33, Rue de Verdun 80400 Ham France France Active (2S)-5-amino-2-[(aminoacetyl)amino]-5-oxopentanoic acid 700-144-0 13115-71-4 - View substance registered dossier
Avara Shannon Pharmaceutical Services Limited Shannon Industrial Estate V14 FX09 Shannon Clare Ireland Ireland Cease Manufacture (2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride (1:1) 695-797-0 93601-86-6 2021 View substance registered dossier
[Confidential] - - - (2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride (1:1) 695-797-0 93601-86-6 - View substance registered dossier
Avara Shannon Pharmaceutical Services Limited Shannon Industrial Estate V14 FX09 Shannon Clare Ireland Ireland Cease Manufacture (2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-aminium (2R)-(2-chlorophenyl)(hydroxy)acetate 814-350-4 1352917-66-8 2021 View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active (2S)-but-3-yn-2-yl methanesulfonate 857-677-8 73647-37-7 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (2S)-N-(2,6-dimethylphenyl)-1-propyl-piperidine-2-carboxamide 617-525-1 84057-95-4 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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