Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
Dibenz [b,f]azepine-5-carbonyl chloride
608-925-7 33948-22-0 Active Intermediate Individual Intermediate use only 31-05-2018 View substance registered dossier
Dibenzo[b,f][1,4]thiazepin-11(10H)-one
438-020-0 3159-07-7 Active Intermediate Individual Intermediate use only 24-06-2010 View substance registered dossier
Dibenzo[b,f][1,4]thiazepin-11(10H)-one, 2-chloro-
700-086-6 3159-04-4 Active Intermediate Individual Intermediate use only 15-01-2014 View substance registered dossier
Dibenzo[b,f][1,4]thiazepin-11(10H)-one, 2-chloro-
700-086-6 3159-04-4 Cease Manufacture Intermediate Individual Cease manufacture 15-10-2012 View substance registered dossier
Dibenzo[b,f][1,4]thiazepin-11-amine, hydrochloride (1:1)
696-106-5 1176987-11-3 Active Intermediate Individual Intermediate use only 19-04-2013 View substance registered dossier
Dibenzo[c,f]pyrazino[1,2-a]azepine, 1,2,3,4,10,14b-hexahydro-, hydrochloride (1:1)
691-142-8 76134-77-5 Active Intermediate Individual Intermediate use only 13-08-2015 View substance registered dossier
Dibenzo[d,f][1,3,2]dioxaphosphepin, 6,6'-[[3,3',5,5'-tetrakis(1,1-dimethylethyl)[1,1'-biphenyl]-2,2'-diyl]bis(oxy)]bis-
482-400-9 138776-88-2 Active Intermediate Individual Intermediate use only 15-09-2020 View substance registered dossier
Dibenzo[d,f][1,3,2]dioxaphosphepin, 6,6'-[[3,3',5,5'-tetrakis(1,1-dimethylethyl)[1,1'-biphenyl]-2,2'-diyl]bis(oxy)]bis-
482-400-9 138776-88-2 Active Intermediate Individual Intermediate use only 07-01-2015 View substance registered dossier
Dibenzo[d,f][1,3,2]dioxaphosphepin, 6,6'-[[3,3',5,5'-tetrakis(1,1-dimethylethyl)[1,1'-biphenyl]-2,2'-diyl]bis(oxy)]bis-
482-400-9 138776-88-2 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Dibenzofuran, 3-ethoxy-4,6-difluoro-7-(pentyloxy)-
942-871-8 1799569-89-3 Active Full Individual ≥ 0 to < 10 tonnes 06-03-2017 View substance registered dossier
DIBENZOYLRESORCIN
439-680-2 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Dibenzylamine
203-117-7 103-49-1 Active Intermediate Individual Intermediate use only 14-03-2013 View substance registered dossier
Dibenzylaminoacetylbrenzcatechin
- - Active Intermediate Individual Intermediate use only 27-06-2011 View substance registered dossier
Dibenzylphenylsulfonium hexafluoroantimonate
ZK RT 1507
417-760-8 134164-24-2 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Diboron trioxide 215-125-8 1303-86-2 No longer Valid Full Individual No longer valid 26-11-2010 View substance registered dossier
Dibutyl phthalate 201-557-4 84-74-2 Active Intermediate Individual Intermediate use only 22-07-2013 View substance registered dossier
Dibutyl phthalate 201-557-4 84-74-2 Cease Manufacture Intermediate Individual Cease manufacture 11-02-2014 View substance registered dossier
Dicadmium tin tetraoxide
700-126-2 12185-56-7 Active Full Individual ≥ 1 to < 10 tonnes 08-02-2013 View substance registered dossier
DICARBOXYLIC ACID
434-560-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Dicerium silicate
CERIUM DISILICATE
418-510-0 13536-88-4 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Dichloride titanium oxide
237-430-5 13780-39-7 Active Intermediate Individual Intermediate use only 28-02-2014 View substance registered dossier
Dichloro(chloromethyl)methylsilane
216-319-5 1558-33-4 Active Intermediate Individual Intermediate use only 17-02-2015 View substance registered dossier
Dichloro(dimethyl)silane
200-901-0 75-78-5 Active Intermediate Individual Intermediate use only 30-11-2012 View substance registered dossier
Dichloro-(3-(3-chloro-4-fluorophenyl)propyl)methylsilane
SILAN DCS
407-180-3 770722-36-6 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
dichloromethane; methylene chloride
200-838-9 75-09-2 No longer Valid Full Individual No longer valid 03-07-2013 View substance registered dossier
Dicyclohexyl ketone
204-336-0 119-60-8 Active Intermediate Individual Intermediate use only 13-03-2013 View substance registered dossier
DICYCLOPENTADIENBISNAPHTHOCHINONDIAZIDSULFONSÄUREMETHYLESTER
422-790-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Diethoxymethane
207-330-6 462-95-3 Active Intermediate Individual Intermediate use only 21-04-2015 View substance registered dossier
diethyl (2-(hydroxymethylcarbamoyl)ethyl)phosphonate;methyl ethyl (2-(hydroxymethylcarbamoyl)ethyl)phosphonate;reaction mass of: dimethyl (2-(hydroxymethylcarbamoyl)ethyl)phosphonate
435-960-3 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
diethyl 1,4-cyclohexanedicarboxylate
417-310-0 72903-27-6 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Diethyl 2-[2-bromoethyl]-2-ethoxycarbonylmalonate
SB-211344
414-710-7 71170-82-6 Active Intermediate Individual Intermediate use only 13-06-2013 View substance registered dossier
Diethyl 2-methyloxosuccinate
212-071-7 759-65-9 Active Intermediate Individual Intermediate use only 30-05-2018 View substance registered dossier
Diethyl 4-oxopentane-1,2-dicarboxylate
ACETONYLBERNSTEINSÄUREESTER; ASE
413-860-0 1187-74-2 Active Intermediate Individual Intermediate use only 14-12-2012 View substance registered dossier
Diethyl carbonate
203-311-1 105-58-8 No longer Valid Full Individual No longer valid 28-05-2013 View substance registered dossier
Diethyl cyclopropane-1,1-dicarboxylate
216-321-6 1559-02-0 Active Intermediate Individual Intermediate use only 31-08-2016 View substance registered dossier
Diethyl diallylmalonate
221-696-4 3195-24-2 Active Intermediate Individual Intermediate use only 13-09-2011 View substance registered dossier
Diethyl dipropylmalonate
227-998-2 6065-63-0 Active Intermediate Individual Intermediate use only 27-09-2011 View substance registered dossier
Diethyl L-glutamate hydrochloride
214-270-4 1118-89-4 Active Intermediate Individual Intermediate use only 07-11-2017 View substance registered dossier
Diethyl N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamate
256-127-9 43170-88-3 Active Intermediate Individual Intermediate use only 19-11-2010 View substance registered dossier
Diethyl phosphonate
212-091-6 762-04-9 Cease Manufacture Intermediate Individual Cease manufacture 17-11-2014 View substance registered dossier
Diethyl phthalate
201-550-6 84-66-2 No longer Valid Full Individual No longer valid 18-12-2015 View substance registered dossier
Diethyl sulphate
200-589-6 64-67-5 Active Intermediate Individual Intermediate use only 16-01-2015 View substance registered dossier
Diethyl thiophosphoryl (Z)-(2-aminothiazol-4-yl)-2-(tert-butoxycarbonyl)methoxyimino acetate
DATMA
426-800-3 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
DIETHYL-MBC
440-160-2 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Diethylamine
203-716-3 109-89-7 Active Intermediate Individual Intermediate use only 19-04-2013 View substance registered dossier
Diethylamine
203-716-3 109-89-7 Active Intermediate Individual Intermediate use only 30-11-2010 View substance registered dossier
Diethylcarbamazine
202-023-3 90-89-1 Active Intermediate Individual Intermediate use only 20-01-2015 View substance registered dossier
Diethylenetriaminepentaacetic acid dianhydride
607-286-1 23911-26-4 Active Intermediate Individual Intermediate use only 05-10-2017 View substance registered dossier
diethylmethoxyborane
425-380-9 7397-46-8 Active Intermediate Individual Intermediate use only 05-11-2014 View substance registered dossier
difluoro(fluorosulphonyl)acetyl fluoride and 3,3,4,4-tetrafluoro-1,2-oxathietane 2,2-dioxide
947-152-2 - Active Intermediate Individual Intermediate use only 08-03-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
POLPHARMA 19 Pelplińska 83-200 Starogard Gdański Poland Poland Active Dibenz [b,f]azepine-5-carbonyl chloride 608-925-7 33948-22-0 - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active Dibenzo[b,f][1,4]thiazepin-11(10H)-one 438-020-0 3159-07-7 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active Dibenzo[b,f][1,4]thiazepin-11(10H)-one, 2-chloro- 700-086-6 3159-04-4 - View substance registered dossier
[Confidential] - - - Dibenzo[b,f][1,4]thiazepin-11(10H)-one, 2-chloro- 700-086-6 3159-04-4 - View substance registered dossier
Fermion Oy Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland Finland Active Dibenzo[b,f][1,4]thiazepin-11-amine, hydrochloride (1:1) 696-106-5 1176987-11-3 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active Dibenzo[c,f]pyrazino[1,2-a]azepine, 1,2,3,4,10,14b-hexahydro-, hydrochloride (1:1) 691-142-8 76134-77-5 - View substance registered dossier
Dow Benelux B.V. OR-20 Postbus 48 4530 AA Terneuzen Netherlands Netherlands Active Dibenzo[d,f][1,3,2]dioxaphosphepin, 6,6'-[[3,3',5,5'-tetrakis(1,1-dimethylethyl)[1,1'-biphenyl]-2,2'-diyl]bis(oxy)]bis- 482-400-9 138776-88-2 2011; 2012; 2020 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Dibenzo[d,f][1,3,2]dioxaphosphepin, 6,6'-[[3,3',5,5'-tetrakis(1,1-dimethylethyl)[1,1'-biphenyl]-2,2'-diyl]bis(oxy)]bis- 482-400-9 138776-88-2 2013; 2015 View substance registered dossier
- - - - Dibenzo[d,f][1,3,2]dioxaphosphepin, 6,6'-[[3,3',5,5'-tetrakis(1,1-dimethylethyl)[1,1'-biphenyl]-2,2'-diyl]bis(oxy)]bis- 482-400-9 138776-88-2 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active Dibenzofuran, 3-ethoxy-4,6-difluoro-7-(pentyloxy)- 942-871-8 1799569-89-3 - View substance registered dossier
- - - - DIBENZOYLRESORCIN 439-680-2 - - View substance registered dossier
REACH24H CONSULTING GROUP Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active Dibenzylamine 203-117-7 103-49-1 - View substance registered dossier
Sanofi Aventis Deutschland GmbH Industriepark Höchst H 831 (Room A0472) z.Hd. Hr. Dr. Schwind 65926 Frankfurt am Main Germany Germany Active Dibenzylaminoacetylbrenzcatechin - - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active Dibenzylphenylsulfonium hexafluoroantimonate 417-760-8 134164-24-2 - View substance registered dossier
Welmet AB Nordenflychtsvägen 64, 5tr 112 51 Stockholm Sweden Sweden No longer Valid Diboron trioxide 215-125-8 1303-86-2 2017 View substance registered dossier
Grace Catalysts & Materials, S.L.U. Carretera N-340, km 1.156 43006 Tarragona Spain Spain Active Dibutyl phthalate 201-557-4 84-74-2 2012; 2013 View substance registered dossier
GRACE GmbH (OR1) In der Hollerhecke 1 67547 Worms Germany Germany Cease Manufacture Dibutyl phthalate 201-557-4 84-74-2 2014 View substance registered dossier
[Confidential] - - - Dicadmium tin tetraoxide 700-126-2 12185-56-7 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active DICARBOXYLIC ACID 434-560-6 - - View substance registered dossier
Philips Applied Technologies - Philips Environment & Safety High Tech Campus 5 5656 AE Eindhoven Netherlands Netherlands Active Dicerium silicate 418-510-0 13536-88-4 - View substance registered dossier
Grace Catalysts & Materials, S.L.U. Carretera N-340, km 1.156 43006 Tarragona Spain Spain Active Dichloride titanium oxide 237-430-5 13780-39-7 2010; 2014 View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active Dichloro(chloromethyl)methylsilane 216-319-5 1558-33-4 2013; 2015 View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active Dichloro(dimethyl)silane 200-901-0 75-78-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active Dichloro-(3-(3-chloro-4-fluorophenyl)propyl)methylsilane 407-180-3 770722-36-6 - View substance registered dossier
Ecotoxward Ltd 381-383 City Road EC1V 1NW London United Kingdom United Kingdom No longer Valid dichloromethane; methylene chloride 200-838-9 75-09-2 2021 View substance registered dossier
CAFFARO INDUSTRIE S.P.A P.le Marinotti, 1 33050 Torviscosa Udine Italy Italy Active Dicyclohexyl ketone 204-336-0 119-60-8 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active DICYCLOPENTADIENBISNAPHTHOCHINONDIAZIDSULFONSÄUREMETHYLESTER 422-790-1 - - View substance registered dossier
Kao Corporation, S.A. Puig dels Tudons, 10 08210 Barbera del Valles Barcelona Spain Spain Active Diethoxymethane 207-330-6 462-95-3 - View substance registered dossier
Huntsman Textile Effects (Germany) GmbH Rehlinger Str. 1 D-86462 Langweid a.Lech Germany Germany Cease Manufacture diethyl (2-(hydroxymethylcarbamoyl)ethyl)phosphonate;methyl ethyl (2-(hydroxymethylcarbamoyl)ethyl)phosphonate;reaction mass of: dimethyl (2-(hydroxymethylcarbamoyl)ethyl)phosphonate 435-960-3 - 2014 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active diethyl 1,4-cyclohexanedicarboxylate 417-310-0 72903-27-6 - View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active Diethyl 2-[2-bromoethyl]-2-ethoxycarbonylmalonate 414-710-7 71170-82-6 - View substance registered dossier
Givaudan Flavours Barneveld Nijverheidsweg 60 3770 Barneveld Netherlands Netherlands Active Diethyl 2-methyloxosuccinate 212-071-7 759-65-9 - View substance registered dossier
POLYNT S.p.A. via Enrico Fermi, 51 I-24020 Scanzorosciate BG Italy Italy Active Diethyl 4-oxopentane-1,2-dicarboxylate 413-860-0 1187-74-2 2012 View substance registered dossier
Jobachem GmbH Am Burgberg 13 37586 Dassel Lower Saxony Germany Germany No longer Valid Diethyl carbonate 203-311-1 105-58-8 2017 View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active Diethyl cyclopropane-1,1-dicarboxylate 216-321-6 1559-02-0 - View substance registered dossier
DuPont Nutrition Biosciences ApS Langebrogade 1 DK-1001 Copenhagen Denmark Denmark Active Diethyl diallylmalonate 221-696-4 3195-24-2 - View substance registered dossier
DuPont Nutrition Biosciences ApS Langebrogade 1 DK-1001 Copenhagen Denmark Denmark Active Diethyl dipropylmalonate 227-998-2 6065-63-0 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active Diethyl L-glutamate hydrochloride 214-270-4 1118-89-4 - View substance registered dossier
Fermion Oy Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland Finland Active Diethyl N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamate 256-127-9 43170-88-3 2010 View substance registered dossier
Innochem GmbH Dorfanger 4 D-15806 Zossen Germany Germany Cease Manufacture Diethyl phosphonate 212-091-6 762-04-9 2019 View substance registered dossier
Koopman International B.V. Distelweg 88 1031 HH Amsterdam Netherlands Netherlands No longer Valid Diethyl phthalate 201-550-6 84-66-2 2017 View substance registered dossier
OQEMA LIMITED (IRELAND) Millienium House Athlone Road N39YW40 Ballymahon, Co Longford Ireland Ireland Active Diethyl sulphate 200-589-6 64-67-5 2015 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active Diethyl thiophosphoryl (Z)-(2-aminothiazol-4-yl)-2-(tert-butoxycarbonyl)methoxyimino acetate 426-800-3 - - View substance registered dossier
- - - - DIETHYL-MBC 440-160-2 - - View substance registered dossier
Fermion Oy Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland Finland Active Diethylamine 203-716-3 109-89-7 - View substance registered dossier
Performance Additives Italy S.p.A. Zona Industriale A 86039 Termoli (CB) Italy Italy Active Diethylamine 203-716-3 109-89-7 - View substance registered dossier
Sigma-Aldrich Ireland Ltd Vale Road . Arklow Co. Wicklow Ireland Ireland Active Diethylcarbamazine 202-023-3 90-89-1 - View substance registered dossier
GE Healthcare AS Nycoveien 1 Postboks 4220 Nydalen 0401 Oslo Oslo Norway Norway Active Diethylenetriaminepentaacetic acid dianhydride 607-286-1 23911-26-4 - View substance registered dossier
ZaCh System ZI La Croix Cadeaux 49242 Avrillè France France Active diethylmethoxyborane 425-380-9 7397-46-8 - View substance registered dossier
Solvay Specialty Polymers Italy S.p.A. Viale Lombardia 20 20021 BOLLATE Italy Italy Active difluoro(fluorosulphonyl)acetyl fluoride and 3,3,4,4-tetrafluoro-1,2-oxathietane 2,2-dioxide 947-152-2 - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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