Registered substances

Registered substances

Registered substances

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Benzoic acid, 2-amino-5-iodo-, methyl ester
616-450-1 77317-55-6 Active Intermediate Individual Intermediate use only 22-09-2016 View substance registered dossier
Ethanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-, (2E)-2-butenedioate (1:1)
616-449-6 773058-82-5 Active Intermediate Joint Intermediate use only 23-05-2018 View substance registered dossier
2(3H)-Thiazolethione, 4-(4-pyridinyl)-
616-441-2 77168-63-9 No longer Valid Intermediate Individual No longer valid 11-03-2011 View substance registered dossier
2(3H)-Thiazolethione, 4-(4-pyridinyl)-
616-441-2 77168-63-9 Active Intermediate Joint Intermediate use only 08-06-2021 View substance registered dossier
3H-1,4-Benzodiazepine-2-acetic acid, 7-chloro-5-(2-fluorophenyl)-α-(hydroxyimino)-, ethyl ester
616-438-6 77132-89-9 Active Intermediate Joint Intermediate use only 15-02-2018 View substance registered dossier
Reaction products of tetrabromophthalic anhydride with 2,2'-oxydiethanol and methyloxirane
616-436-5 77098-07-8 Active Full Joint ≥ 100 to < 1 000 tonnes 28-04-2021 View substance registered dossier
N,N'-bis(2,3-dihydroxypropyl)-5-nitrobenzene-1,3 dicarboxamide
616-392-7 76820-34-3 Active Full Joint ≥ 1 to < 10 tonnes 17-04-2020 View substance registered dossier
Benzeneacetic acid, 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-.alpha.,.alpha.-dimethyl-, ethyl ester
616-391-1 76812-02-7 Active Intermediate Joint Intermediate use only 15-03-2022 View substance registered dossier
Benzeneacetic acid, 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-.alpha.,.alpha.-dimethyl-
616-390-6 76811-98-8 Active Intermediate Individual Intermediate use only 29-05-2013 View substance registered dossier
1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-.beta.-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-
616-385-9 76801-85-9 Active Intermediate Individual Intermediate use only 04-12-2014 View substance registered dossier
1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-.beta.-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-
616-385-9 76801-85-9 Active Intermediate Joint Intermediate use only 29-03-2019 View substance registered dossier
1,3(2H,4H)-Isoquinolinedione, 7-methoxy-2-methyl-
616-380-1 76746-95-7 Active Intermediate Individual Intermediate use only 06-03-2018 View substance registered dossier
2-Buten-1-one, 3-amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (2Z)-
616-378-0 767340-03-4 Active Intermediate Individual Intermediate use only 08-10-2012 View substance registered dossier
Phosphonium, [(2E,4E)-5-[(4R)-4-hydroxy-2,6,6-trimethyl-1-cyclohexen-1-yl]-3-methyl-2,4-pentadien-1-yl]triphenyl-, chloride (1:1)
616-370-7 76686-31-2 Active Intermediate Joint Intermediate use only 25-07-2018 View substance registered dossier
2H-Pyrrol-2-one, 3-ethyl-1,5-dihydro-4-methyl-
616-364-4 766-36-9 Active Intermediate Joint Intermediate use only 05-09-2019 View substance registered dossier
2H-Pyrrol-2-one, 3-ethyl-1,5-dihydro-4-methyl-
616-364-4 766-36-9 Active Intermediate Individual Intermediate use only 15-11-2013 View substance registered dossier
cyclohexanaminium (6R,7S)-3-(acetoxymethyl)-7-methoxy-8-oxo-7-[2-(2-thienyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
616-356-0 765910-82-5 Active Intermediate Joint Intermediate use only 10-11-2017 View substance registered dossier
Benzeneethanamine, N-[(2-chlorophenyl)methyl]-.alpha.-methyl-
616-349-2 76553-22-5 Active Intermediate Joint Intermediate use only 29-03-2018 View substance registered dossier
Cuprate(3-), [3-[2-[5-(hydroxy-.kappa.O)-4-[2-[1-(hydroxy-.kappa.O)-6-(phenylamino)-3-sulfo-2-naphthalenyl]diazenyl-.kappa.N1]-2-methylphenyl]diazenyl]-1,5-naphthalenedisulfonato(5-)]-, sodium (1:3)
616-328-8 76359-37-0 Active Full Joint ≥ 10 to < 100 tonnes 20-07-2017 View substance registered dossier
Cuprate(3-), [3-[2-[5-(hydroxy-.kappa.O)-4-[2-[1-(hydroxy-.kappa.O)-6-(phenylamino)-3-sulfo-2-naphthalenyl]diazenyl-.kappa.N1]-2-methylphenyl]diazenyl]-1,5-naphthalenedisulfonato(5-)]-, sodium (1:3)
616-328-8 76359-37-0 No longer Valid Full Individual No longer valid 18-05-2012 View substance registered dossier
1H-Indeno[5,4-f]quinoline-2,7-dione, tetradecahydro-4a,6a-dimethyl-, (4aR,4bS,6aS,9aS,9bR,11aR)-
616-323-0 76318-69-9 Active Intermediate Joint Intermediate use only 14-06-2016 View substance registered dossier
Acetic acid, 2,2,2-trifluoro-, (2Z)-2-(2-piperazinylidene)hydrazide
616-320-4 849832-73-1 Active Intermediate Individual Intermediate use only 08-10-2012 View substance registered dossier
8-Azabicyclo[3.2.1]octan-3-one, 8-(phenylmethyl)-, oxime
616-314-1 76272-34-9 Active Intermediate Joint Intermediate use only 25-01-2019 View substance registered dossier
1,2,4-Triazolo[4,3-a]pyrazine, 5,6,7,8-tetrahydro-3-(trifluoromethyl)-, hydrochloride (1:1)
616-309-4 762240-92-6 Active Intermediate Individual Intermediate use only 18-10-2012 View substance registered dossier
1,2,4-Triazolo[4,3-a]pyrazine, 5,6,7,8-tetrahydro-3-(trifluoromethyl)-, hydrochloride (1:1)
616-309-4 762240-92-6 Active Intermediate Joint Intermediate use only 31-05-2022 View substance registered dossier
1-(4-chlorophenyl)pyrazol-3-ol
616-307-3 76205-19-1 Active Intermediate Joint Intermediate use only 24-09-2018 View substance registered dossier
Carbamic acid, N-butyl-, 2-propyn-1-yl ester
616-291-8 76114-73-3 Cease Manufacture Intermediate Individual Cease manufacture 22-12-2010 View substance registered dossier
Carbamic acid, N-butyl-, 2-propyn-1-yl ester
616-291-8 76114-73-3 Active Intermediate Joint Intermediate use only 03-05-2016 View substance registered dossier
Carbamic acid, N-butyl-, 2-propyn-1-yl ester
616-291-8 76114-73-3 Active Intermediate Individual Intermediate use only 24-07-2015 View substance registered dossier
1,2,4-Thiadiazole-3-acetic acid, 5-amino-.alpha.-[[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]imino]-, (.alpha.Z)-
616-285-5 76028-96-1 Active Intermediate Individual Intermediate use only 26-04-2013 View substance registered dossier
1,2,4-Thiadiazole-3-acetic acid, 5-amino-.alpha.-[[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]imino]-, (.alpha.Z)-
616-285-5 76028-96-1 Active Intermediate Joint Intermediate use only 09-06-2022 View substance registered dossier
Benzoic acid, 5-amino-2-hydroxy-, sulfate (1:?)
616-280-8 760108-96-1 Active Intermediate Joint Intermediate use only 04-12-2018 View substance registered dossier
Alcohols, C14-15
616-261-4 75782-87-5 Active Full Joint ≥ 1 000 to < 10 000 tonnes 17-08-2015 View substance registered dossier
Benzeneacetonitrile, .alpha.-[(2R)-2-(dimethylamino)propyl]-.alpha.-phenyl-
616-258-8 7576-16-1 Active Intermediate Joint Intermediate use only 12-05-2017 View substance registered dossier
Poly(oxy-1,2-ethanediyl), .alpha.-[3-[(carboxymethyl)methylamino]-2-hydroxypropyl]-.omega.-(4-nonylphenoxy)-, sodium salt (1:1)
616-248-3 75627-31-5 No longer Valid Full Individual No longer valid 15-04-2016 View substance registered dossier
2-Hexadecen-1-ol, 3,7,11,15-tetramethyl-
616-221-6 7541-49-3 Active Full Joint ≥ 1 to < 10 tonnes 16-04-2021 View substance registered dossier
Butanoic acid, 2-methyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, (2S)-
616-212-7 75330-75-5 Active Intermediate Joint Intermediate use only 03-09-2012 View substance registered dossier
1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-(1,1-dimethylethoxy)-2-oxoethyl ester
616-210-6 75302-98-6 Cease Manufacture Intermediate Individual Cease manufacture 17-10-2012 View substance registered dossier
2-Pyrrolidinone, 5-ethenyl-
616-206-4 7529-16-0 Active Intermediate Individual Intermediate use only 16-11-2012 View substance registered dossier
2-Pyridineacetonitrile, .alpha.-[2-[bis(1-methylethyl)amino]ethyl]-.alpha.-phenyl-, 4-methylbenzenesulfonate
616-190-9 75157-06-1 Active Intermediate Joint Intermediate use only 18-10-2016 View substance registered dossier
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-(2-cyanoethyl) 5-methyl ester
616-188-8 75130-24-4 Active Intermediate Joint Intermediate use only 11-05-2016 View substance registered dossier
1,2,4-Thiadiazole-3-acetic acid, 5-amino-.alpha.-(ethoxyimino)-, (.alpha.Z)-
616-178-3 75028-24-9 No longer Valid Intermediate Individual No longer valid 24-06-2013 View substance registered dossier
1,2,4-Thiadiazole-3-acetic acid, 5-amino-.alpha.-(ethoxyimino)-, (.alpha.Z)-
616-178-3 75028-24-9 Active Intermediate Joint Intermediate use only 26-06-2020 View substance registered dossier
1H-Isoindole-1,3(2H)-dione, 2-(11H-dibenz[b,e]azepin-6-ylmethyl)-
616-149-5 74860-00-7 Active Intermediate Joint Intermediate use only 28-11-2019 View substance registered dossier
Phenol, 4-[4-(4-aminophenyl)-1-piperazinyl]-
616-147-4 74853-08-0 Active Intermediate Individual Intermediate use only 29-06-2017 View substance registered dossier
Phenol, 4-[4-(4-aminophenyl)-1-piperazinyl]-
616-147-4 74853-08-0 Active Intermediate Joint Intermediate use only 15-05-2018 View substance registered dossier
1-(4-METHOXYPHENYL)-4-(4-NITROPHENYL)PIPERAZINE
616-145-3 74852-61-2 Active Full Joint ≥ 1 to < 10 tonnes 16-02-2018 View substance registered dossier
1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S,4R)-
616-143-2 74844-91-0 Active Intermediate Individual Intermediate use only 14-06-2016 View substance registered dossier
L-Valine, N-(methoxycarbonyl)-
616-135-9 74761-42-5 Active Intermediate Joint Intermediate use only 17-04-2020 View substance registered dossier
1,4,5-Oxadiazepine, hexahydro-
616-123-3 746595-79-9 No longer Valid Intermediate Individual No longer valid 11-12-2020 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
ORGANICA Feinchemie GmbH Wolfen Ortsteil Wolfen Kunstseidestraße 5 06766 Bitterfeld-Wolfen Germany Germany Active Benzoic acid, 2-amino-5-iodo-, methyl ester 616-450-1 77317-55-6 - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active Ethanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-, (2E)-2-butenedioate (1:1) 616-449-6 773058-82-5 - View substance registered dossier
Fine and Performance Chemicals Ltd Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom United Kingdom No longer Valid 2(3H)-Thiazolethione, 4-(4-pyridinyl)- 616-441-2 77168-63-9 2021 View substance registered dossier
ChemLeader 11 Fine & Performance Chemicals Ltd Długosza 67 43-188 Orzesze Poland Poland Active 2(3H)-Thiazolethione, 4-(4-pyridinyl)- 616-441-2 77168-63-9 - View substance registered dossier
CHEMSAFE srl on behalf of AZO INTERNATIONAL CHEMICAL ltd Via Ribes, 5 10010 Colleretto Giacosa TO Italy Italy Active 2(3H)-Thiazolethione, 4-(4-pyridinyl)- 616-441-2 77168-63-9 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 3H-1,4-Benzodiazepine-2-acetic acid, 7-chloro-5-(2-fluorophenyl)-α-(hydroxyimino)-, ethyl ester 616-438-6 77132-89-9 - View substance registered dossier
ALBEMARLE EUROPE SPRL Parc Scientifique (Einstein) Rue du Bosquet 9 1348 LOUVAIN-LA-NEUVE Belgium Belgium Active Reaction products of tetrabromophthalic anhydride with 2,2'-oxydiethanol and methyloxirane 616-436-5 77098-07-8 2013; 2016; 2018; 2020; 2021 View substance registered dossier
CS Regulatory Ireland Ltd. in its legal capacity as Only Representative of LANXESS Corporation Alexandra House The Sweepstakes D04 C7H2 Dublin Ballsbridge Ireland Ireland Active Reaction products of tetrabromophthalic anhydride with 2,2'-oxydiethanol and methyloxirane 616-436-5 77098-07-8 2019 View substance registered dossier
Interpharma Praha Komoranska 955 14300 Prague Czech Republic Czech Republic Active N,N'-bis(2,3-dihydroxypropyl)-5-nitrobenzene-1,3 dicarboxamide 616-392-7 76820-34-3 - View substance registered dossier
EUROAPI Germany GmbH Brüningstraße 50 65926 Frankfurt am Main Germany Germany Active Benzeneacetic acid, 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-.alpha.,.alpha.-dimethyl-, ethyl ester 616-391-1 76812-02-7 2022 View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active Benzeneacetic acid, 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-.alpha.,.alpha.-dimethyl- 616-390-6 76811-98-8 - View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia Croatia Active 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-.beta.-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)- 616-385-9 76801-85-9 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-.beta.-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)- 616-385-9 76801-85-9 - View substance registered dossier
Midas Pharma GmbH Rheinstrasse 49 55218 Ingelheim Germany Germany Active 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-.beta.-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)- 616-385-9 76801-85-9 - View substance registered dossier
Ercros SA Avenida Diagonal 593-595 08014 Barcelona Spain Spain Active 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-.beta.-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)- 616-385-9 76801-85-9 - View substance registered dossier
KINSY, S.L. Avda. Europa s/n Parque Industrial de Alhama 30840 Alhama de Murcia Murcia Spain Spain Active 1,3(2H,4H)-Isoquinolinedione, 7-methoxy-2-methyl- 616-380-1 76746-95-7 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2-Buten-1-one, 3-amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (2Z)- 616-378-0 767340-03-4 - View substance registered dossier
DSM Nutritional Products France SAS 1 boulevard d'Alsace F-68128 Village-Neuf France France Active Phosphonium, [(2E,4E)-5-[(4R)-4-hydroxy-2,6,6-trimethyl-1-cyclohexen-1-yl]-3-methyl-2,4-pentadien-1-yl]triphenyl-, chloride (1:1) 616-370-7 76686-31-2 2018 View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active 2H-Pyrrol-2-one, 3-ethyl-1,5-dihydro-4-methyl- 616-364-4 766-36-9 - View substance registered dossier
Sanofi Aventis Deutschland GmbH Industriepark Höchst H 831 (Room A0472) z.Hd. Hr. Dr. Schwind 65926 Frankfurt am Main Germany Germany Active 2H-Pyrrol-2-one, 3-ethyl-1,5-dihydro-4-methyl- 616-364-4 766-36-9 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active 2H-Pyrrol-2-one, 3-ethyl-1,5-dihydro-4-methyl- 616-364-4 766-36-9 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active 2H-Pyrrol-2-one, 3-ethyl-1,5-dihydro-4-methyl- 616-364-4 766-36-9 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active cyclohexanaminium (6R,7S)-3-(acetoxymethyl)-7-methoxy-8-oxo-7-[2-(2-thienyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 616-356-0 765910-82-5 - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active Benzeneethanamine, N-[(2-chlorophenyl)methyl]-.alpha.-methyl- 616-349-2 76553-22-5 2018 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active Benzeneethanamine, N-[(2-chlorophenyl)methyl]-.alpha.-methyl- 616-349-2 76553-22-5 - View substance registered dossier
ARCHROMA IBÉRICA, S.L. ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain Spain Active Cuprate(3-), [3-[2-[5-(hydroxy-.kappa.O)-4-[2-[1-(hydroxy-.kappa.O)-6-(phenylamino)-3-sulfo-2-naphthalenyl]diazenyl-.kappa.N1]-2-methylphenyl]diazenyl]-1,5-naphthalenedisulfonato(5-)]-, sodium (1:3) 616-328-8 76359-37-0 - View substance registered dossier
Archroma Germany GmbH Kasteler Str. 45 65203 Wiesbaden Germany Germany Active Cuprate(3-), [3-[2-[5-(hydroxy-.kappa.O)-4-[2-[1-(hydroxy-.kappa.O)-6-(phenylamino)-3-sulfo-2-naphthalenyl]diazenyl-.kappa.N1]-2-methylphenyl]diazenyl]-1,5-naphthalenedisulfonato(5-)]-, sodium (1:3) 616-328-8 76359-37-0 - View substance registered dossier
Archroma France, SAS - OR Rue du Flottage, BP 1 60350 Trosly-Breuil France France Cease Manufacture Cuprate(3-), [3-[2-[5-(hydroxy-.kappa.O)-4-[2-[1-(hydroxy-.kappa.O)-6-(phenylamino)-3-sulfo-2-naphthalenyl]diazenyl-.kappa.N1]-2-methylphenyl]diazenyl]-1,5-naphthalenedisulfonato(5-)]-, sodium (1:3) 616-328-8 76359-37-0 2019 View substance registered dossier
Archroma UK, Ltd 1 Bartholomew Lane EC2N 2AX London United Kingdom United Kingdom No longer Valid Cuprate(3-), [3-[2-[5-(hydroxy-.kappa.O)-4-[2-[1-(hydroxy-.kappa.O)-6-(phenylamino)-3-sulfo-2-naphthalenyl]diazenyl-.kappa.N1]-2-methylphenyl]diazenyl]-1,5-naphthalenedisulfonato(5-)]-, sodium (1:3) 616-328-8 76359-37-0 2017 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active 1H-Indeno[5,4-f]quinoline-2,7-dione, tetradecahydro-4a,6a-dimethyl-, (4aR,4bS,6aS,9aS,9bR,11aR)- 616-323-0 76318-69-9 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active Acetic acid, 2,2,2-trifluoro-, (2Z)-2-(2-piperazinylidene)hydrazide 616-320-4 849832-73-1 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture 8-Azabicyclo[3.2.1]octan-3-one, 8-(phenylmethyl)-, oxime 616-314-1 76272-34-9 2021 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active 8-Azabicyclo[3.2.1]octan-3-one, 8-(phenylmethyl)-, oxime 616-314-1 76272-34-9 2016 View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active 8-Azabicyclo[3.2.1]octan-3-one, 8-(phenylmethyl)-, oxime 616-314-1 76272-34-9 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1,2,4-Triazolo[4,3-a]pyrazine, 5,6,7,8-tetrahydro-3-(trifluoromethyl)-, hydrochloride (1:1) 616-309-4 762240-92-6 - View substance registered dossier
POLPHARMA 19 Pelplińska 83-200 Starogard Gdański Poland Poland Active 1,2,4-Triazolo[4,3-a]pyrazine, 5,6,7,8-tetrahydro-3-(trifluoromethyl)-, hydrochloride (1:1) 616-309-4 762240-92-6 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active 1,2,4-Triazolo[4,3-a]pyrazine, 5,6,7,8-tetrahydro-3-(trifluoromethyl)-, hydrochloride (1:1) 616-309-4 762240-92-6 - View substance registered dossier
Amino Chemicals Ltd Industrial Estate, A61 MRS3000 Marsa Malta Malta Active 1,2,4-Triazolo[4,3-a]pyrazine, 5,6,7,8-tetrahydro-3-(trifluoromethyl)-, hydrochloride (1:1) 616-309-4 762240-92-6 - View substance registered dossier
BASF Schwarzheide GmbH Schipkauer Str. 1 01987 Schwarzheide Brandenburg Germany Germany Active 1-(4-chlorophenyl)pyrazol-3-ol 616-307-3 76205-19-1 - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Cease Manufacture Carbamic acid, N-butyl-, 2-propyn-1-yl ester 616-291-8 76114-73-3 2014 View substance registered dossier
POLY-CHEM GmbH Areal B Farbenstraße 06803 Greppin Sachsen Anhalt Germany Germany Active Carbamic acid, N-butyl-, 2-propyn-1-yl ester 616-291-8 76114-73-3 - View substance registered dossier
TROY CHEMICAL COMPANY BV Poortweg 4C 2612PA Delft Netherlands Netherlands Active Carbamic acid, N-butyl-, 2-propyn-1-yl ester 616-291-8 76114-73-3 - View substance registered dossier
Thor Specialities (UK) Ltd Filial Mölndalsvägen 24 SE-41263 Göteborg Sweden Sweden Active Carbamic acid, N-butyl-, 2-propyn-1-yl ester 616-291-8 76114-73-3 2015 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active 1,2,4-Thiadiazole-3-acetic acid, 5-amino-.alpha.-[[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]imino]-, (.alpha.Z)- 616-285-5 76028-96-1 - View substance registered dossier
ChemLeader 11 Fine & Performance Chemicals Ltd Długosza 67 43-188 Orzesze Poland Poland Active 1,2,4-Thiadiazole-3-acetic acid, 5-amino-.alpha.-[[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]imino]-, (.alpha.Z)- 616-285-5 76028-96-1 - View substance registered dossier
Corden Pharma Latina S.p.A. Via Murillo, 7 IT04013 Sermoneta (LT) Lazio Italy Italy Active 1,2,4-Thiadiazole-3-acetic acid, 5-amino-.alpha.-[[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]imino]-, (.alpha.Z)- 616-285-5 76028-96-1 - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active Benzoic acid, 5-amino-2-hydroxy-, sulfate (1:?) 616-280-8 760108-96-1 2018 View substance registered dossier
Sasol Italy S.p.A. Viale Enrico Forlanini 23 I-20134 Milan Italy Italy Active Alcohols, C14-15 616-261-4 75782-87-5 2011; 2012; 2015 View substance registered dossier
Sanofi Aventis Deutschland GmbH Industriepark Höchst H 831 (Room A0472) z.Hd. Hr. Dr. Schwind 65926 Frankfurt am Main Germany Germany Active Benzeneacetonitrile, .alpha.-[(2R)-2-(dimethylamino)propyl]-.alpha.-phenyl- 616-258-8 7576-16-1 - View substance registered dossier
Nouryon Surface Chemistry AB Stenunge Allé 3 - S-44485 Stenungsund - Sweden Sweden No longer Valid Poly(oxy-1,2-ethanediyl), .alpha.-[3-[(carboxymethyl)methylamino]-2-hydroxypropyl]-.omega.-(4-nonylphenoxy)-, sodium salt (1:1) 616-248-3 75627-31-5 2021 View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active 2-Hexadecen-1-ol, 3,7,11,15-tetramethyl- 616-221-6 7541-49-3 2021 View substance registered dossier
Teva Pharmaceutical Works Private Limited Company Pallagi str. 13 H-4042 Debrecen Hungary Hungary Active Butanoic acid, 2-methyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, (2S)- 616-212-7 75330-75-5 2012 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Cease Manufacture 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-(1,1-dimethylethoxy)-2-oxoethyl ester 616-210-6 75302-98-6 2021 View substance registered dossier
Huvepharma Italia s.r.l. Via Roberto Lepetit, 142 12075 GARESSIO (CN) Italy Italy Active 2-Pyrrolidinone, 5-ethenyl- 616-206-4 7529-16-0 2009; 2010; 2012 View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active 2-Pyridineacetonitrile, .alpha.-[2-[bis(1-methylethyl)amino]ethyl]-.alpha.-phenyl-, 4-methylbenzenesulfonate 616-190-9 75157-06-1 - View substance registered dossier
RECORDATI SPA Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy Italy Active 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-(2-cyanoethyl) 5-methyl ester 616-188-8 75130-24-4 - View substance registered dossier
Fine and Performance Chemicals Ltd Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom United Kingdom No longer Valid 1,2,4-Thiadiazole-3-acetic acid, 5-amino-.alpha.-(ethoxyimino)-, (.alpha.Z)- 616-178-3 75028-24-9 2021 View substance registered dossier
CHEMSAFE srl on behalf of AZO INTERNATIONAL CHEMICAL ltd Via Ribes, 5 10010 Colleretto Giacosa TO Italy Italy Active 1,2,4-Thiadiazole-3-acetic acid, 5-amino-.alpha.-(ethoxyimino)-, (.alpha.Z)- 616-178-3 75028-24-9 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture 1H-Isoindole-1,3(2H)-dione, 2-(11H-dibenz[b,e]azepin-6-ylmethyl)- 616-149-5 74860-00-7 2019 View substance registered dossier
AGC Pharma Chemicals Europe, S.L.U. Camí de la Pomereda, 13 08380 Malgrat de Mar (Barcelona) Spain Spain Active 1H-Isoindole-1,3(2H)-dione, 2-(11H-dibenz[b,e]azepin-6-ylmethyl)- 616-149-5 74860-00-7 2019 View substance registered dossier
SYNTESIA CHEMIE GmbH Martinistr. 13 20251 Hamburg Germany Germany Active Phenol, 4-[4-(4-aminophenyl)-1-piperazinyl]- 616-147-4 74853-08-0 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active Phenol, 4-[4-(4-aminophenyl)-1-piperazinyl]- 616-147-4 74853-08-0 - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active 1-(4-METHOXYPHENYL)-4-(4-NITROPHENYL)PIPERAZINE 616-145-3 74852-61-2 - View substance registered dossier
ZaCh System ZI La Croix Cadeaux 49242 Avrillè France France Active 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S,4R)- 616-143-2 74844-91-0 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active L-Valine, N-(methoxycarbonyl)- 616-135-9 74761-42-5 2019 View substance registered dossier
Gilead Sciences Ireland UC IDA Business &Technology Park Carrigtohill Cork Cork Ireland Ireland Active L-Valine, N-(methoxycarbonyl)- 616-135-9 74761-42-5 - View substance registered dossier
MSD International GmbH (Ballydine Branch) Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active L-Valine, N-(methoxycarbonyl)- 616-135-9 74761-42-5 - View substance registered dossier
Syngenta Ltd Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom United Kingdom No longer Valid 1,4,5-Oxadiazepine, hexahydro- 616-123-3 746595-79-9 2021 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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