Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
µ2-(2-oxido-2-acetato- κ1O-1,3-dicarboxylate- κ2O)-bis[(2-oxidopropane-2-carboxylato-1,3-dicarboxylate)(2-oxidopropane-1,2,3-tricarboxylate- κO)titanium](4+)
949-773-4 - Active Full Joint ≥ 1 to < 10 tonnes 24-06-2019 View substance registered dossier
Esterification products of Guerbet alcohols, C24-26, branched and cyclic with benzene-1,2,4-tricarboxylic acid 1,2-anhydride (3:1)
949-745-1 - Active Full Joint ≥ 1 to < 10 tonnes 01-10-2019 View substance registered dossier
1-O-β-(2 ,3-di-O-alka(e)noyl-6 -O-acetyl-D-mannopyranosyl)-D-erythritol
949-740-4 - Active Full Joint ≥ 0 to < 10 tonnes 05-06-2020 View substance registered dossier
4-hydroxy-3-methyl-5-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]pentan-2-one
949-712-1 - Active Intermediate Joint Intermediate use only 11-02-2019 View substance registered dossier
Saccharomyces cerevisiae cell wall, extracted
949-711-6 - Active Full Joint ≥ 100 to < 1 000 tonnes 12-04-2022 View substance registered dossier
Mixture of Limonene, alpha-Terpinen, gamma-Terpinen, p-Cymene, 1,4-Cineol, 1,8-Cineol and Terpinolene
949-696-6 - Active Intermediate Individual Intermediate use only 01-02-2019 View substance registered dossier
Magnesium potassium fluoride silicate (Mg2.7K0.7Si4O10F2)
949-694-5 - Active Full Joint ≥ 1 to < 10 tonnes 21-01-2022 View substance registered dossier
(2S)‐2‐{[(2S)‐1‐(2‐{[(benzyloxy)carbonyl]amino}acetyl)‐2‐methylpyrrolidin‐2‐yl]formamido}pentanedioic acid
949-609-1 - Active Intermediate Joint Intermediate use only 29-04-2022 View substance registered dossier
Enzymatic hydrolysis products of Sargassum hemiphyllum, ext.
949-588-9 - Active Full Joint ≥ 100 to < 1 000 tonnes 19-02-2019 View substance registered dossier
Reaction mass of 1-(3,3-dimethylcyclohexyl)ethyl acetate and 2,6,6-trimethylcycloheptanol acetate
949-569-5 - Active Full Joint ≥ 1 to < 10 tonnes 20-01-2020 View substance registered dossier
2α-Bromo-6-methylenepregn-4-ene-3,20-dione 17-acetate
949-544-9 1204324-99-1 Active Intermediate Joint Intermediate use only 13-02-2019 View substance registered dossier
(6S)-2,6-dimethyloct-2-ene-8,8-diyl diacetate
949-377-1 - Active Intermediate Joint Intermediate use only 10-05-2019 View substance registered dossier
potassium;3-cyclopentylpropanoate
949-374-5 - Active Intermediate Individual Intermediate use only 13-08-2019 View substance registered dossier
methyl 3-(2-morpholinocyclopenten-1-yl)propanoate
949-350-4 - Active Intermediate Individual Intermediate use only 25-07-2019 View substance registered dossier
Reaction mass of L-alanyl-L-tyrosine hydrochloride and potassium chloride
949-344-1 - Active Intermediate Joint Intermediate use only 08-12-2021 View substance registered dossier
2-[(2-Acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]-1,3-propanediyl bis(4-methoxybenzoate)
949-341-5 - Active Intermediate Individual Intermediate use only 17-12-2018 View substance registered dossier
potassium;1-(4-chlorophenyl)pyrazol-3-olate
949-316-9 1965233-46-8 Active Intermediate Individual Intermediate use only 16-07-2020 View substance registered dossier
N-Cocoyl L-Proline
949-231-7 - Active Full Joint ≥ 1 to < 10 tonnes 20-12-2019 View substance registered dossier
Reaction mass of (4R)-4-(2-methoxypropan-2-yl)-1-methylcyclohexene and cis-1-methoxy-4-(2-methoxypropan-2-yl)-1-methylcyclohexane
949-219-1 - Active Full Joint ≥ 1 to < 10 tonnes 02-01-2019 View substance registered dossier
N-[(E)-2-thiophenylmethylidene]-1H-pyrazol-5-amine
949-159-6 - Active Intermediate Joint Intermediate use only 07-02-2019 View substance registered dossier
Tris(2-propylheptyl) phosphite
949-147-0 1041263-42-6 Active Full Individual ≥ 100 to < 1 000 tonnes 29-03-2021 View substance registered dossier
Rectified Hydrocarbons by-products from synthetic process of Turpentine and acid, alcohols fraction
949-141-8 - Active Full Joint ≥ 100 to < 1 000 tonnes 09-07-2021 View substance registered dossier
Reaction product of castor oil with glycerol
949-117-7 - Active Full Joint ≥ 1 to < 10 tonnes 18-06-2020 View substance registered dossier
Reaction mass of hexadecanoic anhydride and palmitic acid
949-095-9 - Active Intermediate Joint Intermediate use only 31-01-2022 View substance registered dossier
Reaction mass of (S)-2-(benzyl((S)-2-((R)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)-1-((S)-6-fluorochroman-2-yl)ethan-1-ol and (R)-2-(benzyl((R)-2-((R)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)-1-((S)-6-fluorochroman-2-yl)ethan-1-ol
949-087-5 - Active Intermediate Joint Intermediate use only 07-12-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
REACHLaw Ltd. Vänrikinkuja 3 JK 21 02600 Espoo Finland Finland Active µ2-(2-oxido-2-acetato- κ1O-1,3-dicarboxylate- κ2O)-bis[(2-oxidopropane-2-carboxylato-1,3-dicarboxylate)(2-oxidopropane-1,2,3-tricarboxylate- κO)titanium](4+) 949-773-4 - - View substance registered dossier
TEMIX OLEO S.R.L. VIA PIERO PORTALUPPI 17 20138 MILANO Italy Italy Active Esterification products of Guerbet alcohols, C24-26, branched and cyclic with benzene-1,2,4-tricarboxylic acid 1,2-anhydride (3:1) 949-745-1 - - View substance registered dossier
SCAS Europe S.A./N.V. Leonardo Da Vincilaan 19 B-1831 Diegem Belgium Belgium Active 1-O-β-(2 ,3-di-O-alka(e)noyl-6 -O-acetyl-D-mannopyranosyl)-D-erythritol 949-740-4 - - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active 4-hydroxy-3-methyl-5-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]pentan-2-one 949-712-1 - - View substance registered dossier
BIO SPRINGER 103 rue Jean-Jaurès 94704 Maisons Alfort cedex France France Active Saccharomyces cerevisiae cell wall, extracted 949-711-6 - 2021; 2022 View substance registered dossier
Lesaffre International OR1 137 rue Gabriel Péri 59700 Marcq en Baroeul France France Active Saccharomyces cerevisiae cell wall, extracted 949-711-6 - - View substance registered dossier
DSM Food Specialties B.V. Alexander Fleminglaan 1 2613 AX Delft Netherlands Netherlands Active Saccharomyces cerevisiae cell wall, extracted 949-711-6 - - View substance registered dossier
Metadynea Austria GmbH Hafenstrasse 77 A-3500 Krems Austria Austria Active Mixture of Limonene, alpha-Terpinen, gamma-Terpinen, p-Cymene, 1,4-Cineol, 1,8-Cineol and Terpinolene 949-696-6 - - View substance registered dossier
TSG_11-049 Im Fliegerhorst 12 38642 Goslar Germany Germany Active Magnesium potassium fluoride silicate (Mg2.7K0.7Si4O10F2) 949-694-5 - 2019; 2022 View substance registered dossier
Corden Pharma Bergamo S.p.A. Via Bergamo, 121 IT-24047 Treviglio BG Italy Italy Active (2S)‐2‐{[(2S)‐1‐(2‐{[(benzyloxy)carbonyl]amino}acetyl)‐2‐methylpyrrolidin‐2‐yl]formamido}pentanedioic acid 949-609-1 - 2022 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2S)‐2‐{[(2S)‐1‐(2‐{[(benzyloxy)carbonyl]amino}acetyl)‐2‐methylpyrrolidin‐2‐yl]formamido}pentanedioic acid 949-609-1 - - View substance registered dossier
Chemical Inspection & Regulation Service Limited (Beijing Leili Marine Bioindustry Inc.) Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active Enzymatic hydrolysis products of Sargassum hemiphyllum, ext. 949-588-9 - 2019 View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active Reaction mass of 1-(3,3-dimethylcyclohexyl)ethyl acetate and 2,6,6-trimethylcycloheptanol acetate 949-569-5 - - View substance registered dossier
Symrise H17 Mühlenfeldstr. 1 37603 Holzminden Germany Germany Active Reaction mass of 1-(3,3-dimethylcyclohexyl)ethyl acetate and 2,6,6-trimethylcycloheptanol acetate 949-569-5 - - View substance registered dossier
Farmabios Spa Via Pavia, 1 27027 Gropello Cairoli PV Italy Italy Active 2α-Bromo-6-methylenepregn-4-ene-3,20-dione 17-acetate 949-544-9 1204324-99-1 - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (6S)-2,6-dimethyloct-2-ene-8,8-diyl diacetate 949-377-1 - - View substance registered dossier
Chemische Fabrik Karl Bucher GmbH An der Guenz 1 89367 Waldstetten Germany Germany Active potassium;3-cyclopentylpropanoate 949-374-5 - - View substance registered dossier
Chemische Fabrik Karl Bucher GmbH An der Guenz 1 89367 Waldstetten Germany Germany Active methyl 3-(2-morpholinocyclopenten-1-yl)propanoate 949-350-4 - - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active Reaction mass of L-alanyl-L-tyrosine hydrochloride and potassium chloride 949-344-1 - 2021 View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active 2-[(2-Acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]-1,3-propanediyl bis(4-methoxybenzoate) 949-341-5 - - View substance registered dossier
BASF Schwarzheide GmbH Schipkauer Str. 1 01987 Schwarzheide Brandenburg Germany Germany Active potassium;1-(4-chlorophenyl)pyrazol-3-olate 949-316-9 1965233-46-8 2020 View substance registered dossier
Sinerga Via della Pacciarna 67 21050 Gorla Maggiore Varese Italy Italy Active N-Cocoyl L-Proline 949-231-7 - - View substance registered dossier
FIRMENICH GRASSE SAS OR 7 Parc Industriel Le Bois de Grasse 06130 Grasse France France Active Reaction mass of (4R)-4-(2-methoxypropan-2-yl)-1-methylcyclohexene and cis-1-methoxy-4-(2-methoxypropan-2-yl)-1-methylcyclohexane 949-219-1 - 2019 View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active N-[(E)-2-thiophenylmethylidene]-1H-pyrazol-5-amine 949-159-6 - - View substance registered dossier
[Confidential] - - - N-[(E)-2-thiophenylmethylidene]-1H-pyrazol-5-amine 949-159-6 - - View substance registered dossier
Valtris Enterprises France (OR-UK) ZI Baleycourt 55103 Verdun France France Active Tris(2-propylheptyl) phosphite 949-147-0 1041263-42-6 2019; 2020; 2021 View substance registered dossier
V. MANE FILS 620 route de Grasse 06620 Le Bar sur Loup France France Active Rectified Hydrocarbons by-products from synthetic process of Turpentine and acid, alcohols fraction 949-141-8 - - View substance registered dossier
LLUCH ESSENCE, S.L.U. Lo Gaiter, 160 08820 EL PRAT DE LLOBREGAT CATALUÑA Spain Spain Active Rectified Hydrocarbons by-products from synthetic process of Turpentine and acid, alcohols fraction 949-141-8 - 2019; 2020 View substance registered dossier
Croda Iberica SA Mevisa Site Carretera C-35 Km 72 (Hostalric-Blanes) 08495 Fogars de la Selva Barcelona Spain Spain Active Reaction product of castor oil with glycerol 949-117-7 - 2020 View substance registered dossier
R&R Extrakte GmbH Nattermannallee 1 50829 Cologne Germany Germany Active Reaction mass of hexadecanoic anhydride and palmitic acid 949-095-9 - - View substance registered dossier
Lipoid GmbH Frigenstr. 4 67065 Ludwigshafen Germany Germany Active Reaction mass of hexadecanoic anhydride and palmitic acid 949-095-9 - - View substance registered dossier
Lodichem S.r.l. Via delle Rimembranze, 1 26582 Mairano di Casaletto Lodigiano (Lodi) Italy Italy Active Reaction mass of (S)-2-(benzyl((S)-2-((R)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)-1-((S)-6-fluorochroman-2-yl)ethan-1-ol and (R)-2-(benzyl((R)-2-((R)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)-1-((S)-6-fluorochroman-2-yl)ethan-1-ol 949-087-5 - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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