Registered substances

Data platform availability banner - registered substances

The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.


 

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
(2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile
441-070-6 61826-76-4 No longer Valid NONS Individual No longer valid 04-06-2012 View substance registered dossier
(2S)-2-{[(1E)-(5-chloro-2-hydroxyphenyl)(phenyl)methylene]amino}-3-methylbutanoic acid
609-516-6 38075-43-3 Cease Manufacture Intermediate Joint Cease manufacture 18-01-2018 View substance registered dossier
(2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanonone
477-290-4 - Active NONS Joint Tonnage data confidential 01-03-2013 View substance registered dossier
(2S)-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanoic acid
430-900-2 192725-50-1 Active Intermediate Joint Intermediate use only 14-06-2018 View substance registered dossier
(2S)-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanoic acid
430-900-2 192725-50-1 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(2S)-3-methyl-2-(N-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1-biphenyl]-4-yl]methyl}pentanamido)butanoic acid
604-045-2 137862-53-4 Active Full Joint ≥ 0 to < 10 tonnes 12-02-2020 View substance registered dossier
(2S)-3-methyl-2-(N-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1-biphenyl]-4-yl]methyl}pentanamido)butanoic acid
604-045-2 137862-53-4 Active Intermediate Individual Intermediate use only 07-08-2014 View substance registered dossier
(2S)-4-amino-2-hydroxy-butanoic acid
670-305-7 40371-51-5 Active Intermediate Individual Intermediate use only 27-01-2020 View substance registered dossier
(2S)-5-amino-2-[(aminoacetyl)amino]-5-oxopentanoic acid
700-144-0 13115-71-4 Active Full Joint ≥ 1 to < 10 tonnes 10-03-2023 View substance registered dossier
(2S)-5-amino-2-{[(2S)-2-aminopropanoyl]amino}-5-oxopentanoic acid
475-290-9 - Active Full Joint ≥ 1 to < 10 tonnes 15-11-2022 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
DOW CHEMICAL COMPANY LTD Diamond House, Lotus Park Kingsbury Crescent Middx UB7 0DQ Staines Middx United Kingdom United Kingdom No longer Valid (2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile 441-070-6 61826-76-4 2021 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Cease Manufacture (2S)-2-{[(1E)-(5-chloro-2-hydroxyphenyl)(phenyl)methylene]amino}-3-methylbutanoic acid 609-516-6 38075-43-3 2022 View substance registered dossier
Első Vegyi Industria ZRt. Kartács utca 6. H-1139 BUDAPEST Hungary Hungary Active (2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanonone 477-290-4 - - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanonone 477-290-4 - 2019 View substance registered dossier
Gruenenthal GmbH Zieglerstrasse 6 52078 Aachen Germany Germany Active (2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanonone 477-290-4 - - View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active (2S)-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanoic acid 430-900-2 192725-50-1 2011; 2018 View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (2S)-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanoic acid 430-900-2 192725-50-1 - View substance registered dossier
Novartis Grimsby Limited Moody Lane, Pyewipe DN31 2SR Grimsby N.E. Lincolnshire United Kingdom United Kingdom No longer Valid (2S)-3-methyl-2-(N-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1-biphenyl]-4-yl]methyl}pentanamido)butanoic acid 604-045-2 137862-53-4 2021 View substance registered dossier
Novartis Ringaskiddy Limited . . Ringaskiddy County Cork Ireland Ireland Active (2S)-3-methyl-2-(N-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1-biphenyl]-4-yl]methyl}pentanamido)butanoic acid 604-045-2 137862-53-4 2014 View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy IE Ringaskiddy Cork Ireland Ireland Active (2S)-3-methyl-2-(N-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1-biphenyl]-4-yl]methyl}pentanamido)butanoic acid 604-045-2 137862-53-4 2014 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active (2S)-4-amino-2-hydroxy-butanoic acid 670-305-7 40371-51-5 - View substance registered dossier
Evonik Rexim S.A.S. 33, Rue de Verdun 80400 Ham France France Active (2S)-5-amino-2-[(aminoacetyl)amino]-5-oxopentanoic acid 700-144-0 13115-71-4 2023 View substance registered dossier
Evonik Rexim S.A.S. 33, Rue de Verdun 80400 Ham France France Active (2S)-5-amino-2-{[(2S)-2-aminopropanoyl]amino}-5-oxopentanoic acid 475-290-9 - 2022 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.