Registered substances

Registered substances

Registered substances

Please note:

As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
(R)-1-chloro-2,3-epoxypropane
(R)-EPICHLOROHYDRIN
424-280-2 51594-55-9 Cease Manufacture Intermediate Joint Cease manufacture 20-03-2018 View substance registered dossier
(R)-1-chloro-2,3-epoxypropane
(R)-EPICHLOROHYDRIN
424-280-2 51594-55-9 Active NONS Joint Tonnage data confidential 15-04-2011 View substance registered dossier
(R)-1-cyclohexa-1,4-dienyl-1-methoxycarbonyl-methylammoniumchloride
444-320-2 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-1-hydroxy-1-phenylacetone
217-285-4 1798-60-3 Active Intermediate Individual Intermediate use only 08-05-2013 View substance registered dossier
(R)-10-β-D-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)anthracen-9(10H)-one
215-808-0 1415-73-2 Active Intermediate Joint Intermediate use only 06-04-2018 View substance registered dossier
(R)-12-hydroxy-N-(2-hydroxyethyl)oleamide
203-368-2 106-16-1 Active Intermediate Joint Intermediate use only 18-05-2016 View substance registered dossier
(R)-2,2,3-trimethylcyclopent-3-ene-1-acetaldehyde
224-815-8 4501-58-0 Active Intermediate Joint Intermediate use only 30-11-2021 View substance registered dossier
(R)-2-(2,4-Difluorphenyl)-1,1-difluor-3-(tetrazol-1-yl)-1-{5-[4-(2,2,2-trifluorethoxy)-phenyl]-2-pyridyl}-2-propanol-(R,R)-tartrate
845-262-4 1809816-36-1 Cease Manufacture Full Joint Cease manufacture 30-09-2020 View substance registered dossier
(R)-2-(2,5-difluorophenyl)pyrrolidine (R)-2-hydroxysuccinate
845-727-1 1919868-77-1 Active Intermediate Individual Intermediate use only 18-01-2022 View substance registered dossier
(R)-2-(4-hydroxyphenoxy)propanoic acid
D-HPPA; HPOPS
407-960-3 94050-90-5 No longer Valid Intermediate Individual No longer valid 28-09-2010 View substance registered dossier
(R)-2-(4-hydroxyphenoxy)propanoic acid
D-HPPA; HPOPS
407-960-3 94050-90-5 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propionic acid
440-090-2 86123-10-6 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
(R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol
929-946-0 - Active Intermediate Joint Intermediate use only 05-12-2017 View substance registered dossier
(R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol (R)-acetoxy(phenyl)acetate
929-947-6 - Active Intermediate Joint Intermediate use only 31-10-2017 View substance registered dossier
(R)-2-acetamido-3-naphthyl-2-yl-propionic acid
(R)-2-ACETAMIDO-3-NAPHTHYLEN-2-YL-PROPIONIC ACID
440-450-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-2-amino-3-phenylpropanol
226-086-1 5267-64-1 Active Intermediate Joint Intermediate use only 29-11-2018 View substance registered dossier
(R)-2-aminobutan-1-ol
227-476-4 5856-63-3 Active Intermediate Joint Intermediate use only 19-07-2019 View substance registered dossier
(R)-2-dimethylamino-4-imino-6-methyl-1,4,5,6-tetrahydro-1,3,5-triazine, L-tartrate
942-402-7 - Active Intermediate Joint Intermediate use only 24-09-2021 View substance registered dossier
(R)-2-tert-butoxycarbonylamino-3-(4-chlorophenyl)propionic acid
(R)-2-TERT-BUTOXYCARBONYLAMINO-3-(4-CHLOROPHENYL)-PROPIONIC ACID
438-070-3 57292-44-1 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-2-tert-butoxycarbonylamino-3-(pyridin-3-yl)propionic acid
(R)-2-TERT-BUTOXYCARBONYLAMINO-3-(PYRIDIN-3-YL) PROPIONIC ACID
441-200-1 98266-33-2 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-3,7-dimethyl-1,6-octadien-3-ol 204-811-2 126-91-0 Active Full Joint ≥ 10 to < 100 tonnes 16-12-2020 View substance registered dossier
(R)-3,7-dimethyloct-6-en-1-ol
214-250-5 1117-61-9 Active Intermediate Joint Intermediate use only 25-05-2018 View substance registered dossier
(R)-3,7-dimethyloct-6-enal
219-194-5 2385-77-5 Active Intermediate Joint Intermediate use only 13-02-2019 View substance registered dossier
(R)-3-(1-hydroxyethyl)phenyl ethyl(methyl)carbamate
843-372-7 856408-80-5 Active Intermediate Joint Intermediate use only 23-09-2019 View substance registered dossier
(R)-3-(1-methyl-2-pyrrolidinylmethyl)-5-[2-(phenylsulphonyl)ethyl]-1H-indole
921-685-0 - Active Intermediate Joint Intermediate use only 05-08-2022 View substance registered dossier
(R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid
691-120-8 486460-00-8 Active Intermediate Joint Intermediate use only 31-05-2022 View substance registered dossier
(R)-3-[(1-methylpyrrolidin-2-yl)methyl]-5-[2-(phenylsulfonyl)ethenyl]-1H-indole
430-560-5 180637-89-2 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-3-chloropropane-1,2-diol
435-560-9 57090-45-6 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(R)-3-chloropropane-1,2-diol
435-560-9 57090-45-6 Active Intermediate Joint Intermediate use only 25-04-2018 View substance registered dossier
(R)-3-cyclohexyl-2-hydroxypropionic acid
812-501-9 156469-00-0 Active Intermediate Joint Intermediate use only 01-06-2018 View substance registered dossier
(R)-3-phenyllactic acid
230-803-3 7326-19-4 Active Intermediate Joint Intermediate use only 17-05-2018 View substance registered dossier
(R)-4-(4-dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemi (2R, 3R)-2,3-bis((4-methylbenzoyl)oxy)succinoate
949-784-4 - Active Intermediate Individual Intermediate use only 25-03-2019 View substance registered dossier
(R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile
430-760-2 219861-18-4 Active Intermediate Joint Intermediate use only 26-03-2019 View substance registered dossier
(R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile
430-760-2 219861-18-4 Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
(R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide (7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate
920-209-9 - Active Intermediate Joint Intermediate use only 30-05-2018 View substance registered dossier
(R)-5-(2-Phenylsulphonylethenyl)-3(N-Methylpyrrolidine-2-ylmethyl)-1-H-indole methane sulphonic acid)
880-102-7 1196663-24-7 Active Intermediate Joint Intermediate use only 22-02-2022 View substance registered dossier
(R)-5-bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole
UK-111,975
422-390-5 143322-57-0 Active NONS Joint Tonnage data confidential 10-04-2020 View substance registered dossier
(R)-5-bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole
UK-111,975
422-390-5 143322-57-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-5-Bromo-3-[(1-methyl-2-pyrrolidinyl)methyl]-1H-indol oxalate
846-313-3 1196663-29-2 Active Intermediate Joint Intermediate use only 02-12-2019 View substance registered dossier
(R)-5-isopropyl-2-methylcyclohexa-1,3-diene
224-167-6 4221-98-1 Active Full Joint ≥ 10 to < 100 tonnes 30-05-2018 View substance registered dossier
(R)-6-(isopropyl)-3-methylcyclohex-2-en-1-one
224-957-0 4573-50-6 Active Full Joint ≥ 1 to < 10 tonnes 24-08-2018 View substance registered dossier
(R)-6-(isopropyl)-3-methylcyclohex-2-en-1-one
224-957-0 4573-50-6 Active Intermediate Individual Intermediate use only 11-06-2019 View substance registered dossier
(R)-[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetic acid
264-133-8 63422-71-9 Active Intermediate Joint Intermediate use only 29-10-2021 View substance registered dossier
(R)-cyclohex-3-enecarboxylic acid
634-674-8 5709-98-8 Active Intermediate Joint Intermediate use only 11-09-2017 View substance registered dossier
(R)-lactic acid
233-713-2 10326-41-7 Active Full Joint ≥ 1 000 to < 10 000 tonnes 22-09-2021 View substance registered dossier
(R)-methyl(α-methylphenethyl)ammonium [R-(R*,R*)]-hydrogen tartrate
298-036-7 93777-08-3 Active Intermediate Joint Intermediate use only 07-01-2022 View substance registered dossier
(R)-p-mentha-1,8-diene
227-813-5 5989-27-5 Active Full Joint ≥ 1 000 to < 10 000 tonnes 01-06-2022 View substance registered dossier
(R)-quinuclidin-3-ol
246-857-6 25333-42-0 Active Full Joint ≥ 1 to < 10 tonnes 01-05-2018 View substance registered dossier
(R)-quinuclidin-3-ol
246-857-6 25333-42-0 Active Intermediate Joint Intermediate use only 11-04-2022 View substance registered dossier
(R)-thiazolidine-4-carboxylic acid
252-106-3 34592-47-7 Active Full Joint ≥ 1 to < 10 tonnes 03-05-2022 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Cease Manufacture (R)-1-chloro-2,3-epoxypropane 424-280-2 51594-55-9 2022 View substance registered dossier
Labcorp CLINICAL DEVELOPMENT SA 171 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active (R)-1-chloro-2,3-epoxypropane 424-280-2 51594-55-9 - View substance registered dossier
Labcorp Development SA 169 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active (R)-1-chloro-2,3-epoxypropane 424-280-2 51594-55-9 2011 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (R)-1-cyclohexa-1,4-dienyl-1-methoxycarbonyl-methylammoniumchloride 444-320-2 - - View substance registered dossier
Deretil S.A.U. Villaricos, s/n 04618 Cuevas del Almanzora Almeria Spain Spain Cease Manufacture (R)-1-cyclohexa-1,4-dienyl-1-methoxycarbonyl-methylammoniumchloride 444-320-2 - 2019 View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active (R)-1-hydroxy-1-phenylacetone 217-285-4 1798-60-3 2013 View substance registered dossier
ICROM S.r.l Via delle arti, 33 20863 Concorezzo Italy Italy Active (R)-10-β-D-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)anthracen-9(10H)-one 215-808-0 1415-73-2 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (R)-12-hydroxy-N-(2-hydroxyethyl)oleamide 203-368-2 106-16-1 - View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Active (R)-2,2,3-trimethylcyclopent-3-ene-1-acetaldehyde 224-815-8 4501-58-0 2021 View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (R)-2,2,3-trimethylcyclopent-3-ene-1-acetaldehyde 224-815-8 4501-58-0 - View substance registered dossier
Givaudan Iberica SA Pla d'en Batlle s/n 08470 San Celoni Barcelona Spain Spain Active (R)-2,2,3-trimethylcyclopent-3-ene-1-acetaldehyde 224-815-8 4501-58-0 2013 View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Cease Manufacture (R)-2-(2,4-Difluorphenyl)-1,1-difluor-3-(tetrazol-1-yl)-1-{5-[4-(2,2,2-trifluorethoxy)-phenyl]-2-pyridyl}-2-propanol-(R,R)-tartrate 845-262-4 1809816-36-1 2022 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active (R)-2-(2,5-difluorophenyl)pyrrolidine (R)-2-hydroxysuccinate 845-727-1 1919868-77-1 2022 View substance registered dossier
NuFarm Limited Wyke Lane BD12 9EJ Wyke West Yorkshire United Kingdom United Kingdom No longer Valid (R)-2-(4-hydroxyphenoxy)propanoic acid 407-960-3 94050-90-5 2021 View substance registered dossier
RHODIA OPERATIONS 52 rue de la Haie Coq 93300 AUBERVILLIERS France France Active (R)-2-(4-hydroxyphenoxy)propanoic acid 407-960-3 94050-90-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active (R)-2-(4-hydroxyphenoxy)propanoic acid 407-960-3 94050-90-5 - View substance registered dossier
- - - - (R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propionic acid 440-090-2 86123-10-6 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol 929-946-0 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol (R)-acetoxy(phenyl)acetate 929-947-6 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-2-acetamido-3-naphthyl-2-yl-propionic acid 440-450-9 - - View substance registered dossier
PMC ISOCHEM 32 rue Lavoisier 91710 VERT LE PETIT France France Active (R)-2-amino-3-phenylpropanol 226-086-1 5267-64-1 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (R)-2-amino-3-phenylpropanol 226-086-1 5267-64-1 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (R)-2-aminobutan-1-ol 227-476-4 5856-63-3 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active (R)-2-aminobutan-1-ol 227-476-4 5856-63-3 2019 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (R)-2-dimethylamino-4-imino-6-methyl-1,4,5,6-tetrahydro-1,3,5-triazine, L-tartrate 942-402-7 - 2018; 2021 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France No longer Valid (R)-2-dimethylamino-4-imino-6-methyl-1,4,5,6-tetrahydro-1,3,5-triazine, L-tartrate 942-402-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-2-tert-butoxycarbonylamino-3-(4-chlorophenyl)propionic acid 438-070-3 57292-44-1 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-2-tert-butoxycarbonylamino-3-(pyridin-3-yl)propionic acid 441-200-1 98266-33-2 - View substance registered dossier
Chemical Inspection & Regulation Service Limited Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (R)-3,7-dimethyl-1,6-octadien-3-ol 204-811-2 126-91-0 - View substance registered dossier
International Flavors & Fragrances, I.F.F. (France) S.A.S Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (R)-3,7-dimethyl-1,6-octadien-3-ol 204-811-2 126-91-0 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (R)-3,7-dimethyl-1,6-octadien-3-ol 204-811-2 126-91-0 2018 View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (R)-3,7-dimethyloct-6-en-1-ol 214-250-5 1117-61-9 - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (R)-3,7-dimethyloct-6-enal 219-194-5 2385-77-5 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (R)-3,7-dimethyloct-6-enal 219-194-5 2385-77-5 2013; 2018; 2019 View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (R)-3-(1-hydroxyethyl)phenyl ethyl(methyl)carbamate 843-372-7 856408-80-5 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (R)-3-(1-methyl-2-pyrrolidinylmethyl)-5-[2-(phenylsulphonyl)ethyl]-1H-indole 921-685-0 - - View substance registered dossier
Upjohn Manufacturing Ireland Unlimited Little Island T45 F627 Co. Cork Ireland Ireland Active (R)-3-(1-methyl-2-pyrrolidinylmethyl)-5-[2-(phenylsulphonyl)ethyl]-1H-indole 921-685-0 - - View substance registered dossier
POLPHARMA 19 Pelplińska 83-200 Starogard Gdański Poland Poland Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
REACHLINKED OÜ Ahtri tn 12 10151 Tallinn Estonia Estonia Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
MOEHS BCN, S.L. C/ Zenc, 12 08755 Castellbisbal Barcelona Spain Spain Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
Amino Chemicals Ltd Industrial Estate, A61 MRS3000 Marsa Malta Malta Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-3-[(1-methylpyrrolidin-2-yl)methyl]-5-[2-(phenylsulfonyl)ethenyl]-1H-indole 430-560-5 180637-89-2 - View substance registered dossier
COVANCE CLINICAL DEVELOPMENT SA 171 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Cease Manufacture (R)-3-chloropropane-1,2-diol 435-560-9 57090-45-6 2012 View substance registered dossier
Labcorp Development SA 169 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active (R)-3-chloropropane-1,2-diol 435-560-9 57090-45-6 2018 View substance registered dossier
A.M.S.A. Anonima Materie Sintetiche e Affini S.p.A. Viale del Ghisallo, 20 20151 Milano Italy Italy Active (R)-3-chloropropane-1,2-diol 435-560-9 57090-45-6 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (R)-3-cyclohexyl-2-hydroxypropionic acid 812-501-9 156469-00-0 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (R)-3-phenyllactic acid 230-803-3 7326-19-4 - View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active (R)-4-(4-dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemi (2R, 3R)-2,3-bis((4-methylbenzoyl)oxy)succinoate 949-784-4 - - View substance registered dossier
H. Lundbeck A/S Ottiliavej 7-9 2500 Copenhagen Denmark Denmark Active (R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 430-760-2 219861-18-4 2019 View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active (R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 430-760-2 219861-18-4 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 430-760-2 219861-18-4 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 430-760-2 219861-18-4 - View substance registered dossier
Synthon, s.r.o. Brněnská 32 678 01 Blansko Czech Republic Czech Republic Active (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide (7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate 920-209-9 - - View substance registered dossier
Upjohn Manufacturing Ireland Unlimited Little Island T45 F627 Co. Cork Ireland Ireland Active (R)-5-(2-Phenylsulphonylethenyl)-3(N-Methylpyrrolidine-2-ylmethyl)-1-H-indole methane sulphonic acid) 880-102-7 1196663-24-7 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (R)-5-bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole 422-390-5 143322-57-0 2020 View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active (R)-5-bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole 422-390-5 143322-57-0 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland No longer Valid (R)-5-bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole 422-390-5 143322-57-0 2013 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (R)-5-Bromo-3-[(1-methyl-2-pyrrolidinyl)methyl]-1H-indol oxalate 846-313-3 1196663-29-2 - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (R)-5-isopropyl-2-methylcyclohexa-1,3-diene 224-167-6 4221-98-1 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (R)-5-isopropyl-2-methylcyclohexa-1,3-diene 224-167-6 4221-98-1 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (R)-6-(isopropyl)-3-methylcyclohex-2-en-1-one 224-957-0 4573-50-6 2018 View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (R)-6-(isopropyl)-3-methylcyclohex-2-en-1-one 224-957-0 4573-50-6 - View substance registered dossier
FRESENIUS KABI iPSUM s.r.l. Via Roma, 108 20060 Cassina de' Pecchi (MI) Italy Italy Active (R)-[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetic acid 264-133-8 63422-71-9 2021 View substance registered dossier
REACHLaw Ltd Vänrikinkuja 3 JK 21 02600 Espoo Finland Finland Active (R)-[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetic acid 264-133-8 63422-71-9 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (R)-cyclohex-3-enecarboxylic acid 634-674-8 5709-98-8 - View substance registered dossier
Purac Bioquímica S.A.U. Gran Vial 19-25 08160 Montmeló (Barcelona) Spain Spain Active (R)-lactic acid 233-713-2 10326-41-7 - View substance registered dossier
Purac Biochem bv Arkelsedijk 46 4206AC Gorinchem Netherlands Netherlands Active (R)-lactic acid 233-713-2 10326-41-7 2021 View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active (R)-lactic acid 233-713-2 10326-41-7 - View substance registered dossier
[Confidential] - - - (R)-methyl(α-methylphenethyl)ammonium [R-(R*,R*)]-hydrogen tartrate 298-036-7 93777-08-3 - View substance registered dossier
FIRMENICH GRASSE SAS OR 8 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 2022 View substance registered dossier
Novachem Aromatici S.r.L. V.Carlo Noè, 7 21013 Gallarate Varese Italy Italy Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
Roche Diagnostics GmbH Sandhoferstrasse 116 68305 Mannheim Germany Germany Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
CITROSUCO SPAIN, S.L.U. POLIGONO INDUSTRIAL MATACHE, PARCELA 18-53 14700 PALMA DEL RIO CORDOBA Spain Spain Cease Manufacture (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 2020 View substance registered dossier
Ramboll Belgium bvba 46 Meersbloem-Melden 9700 Oudenaarde Belgium Belgium Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 2017 View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
Symrise Granada, S.A.U. Crta. Armilla Km 2, 5 18100 Armilla Granada Spain Spain Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 2018 View substance registered dossier
Sensient Technologies Europe GmbH Geesthachter Straße 103 21502 Geesthacht Germany Germany Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
ERNESTO VENTOS, S.A. Carretera Reial 120B 08960 Sant Just Desvern Spain Spain Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 2018 View substance registered dossier
FIRMENICH GRASSE SAS OR 3 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
PeelPioneers B.V. Jacob van Lennepstraat 235 C 1053 JC Amsterdam Netherlands Netherlands Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
BERNARDI Parc Industriel Les Bois de Grasse Avenue Michel Chevalier 06130 GRASSE France France Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
Dako Denmark ApS Produktionsvej 42 2600 Glostrup Denmark Denmark Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 2012; 2014; 2016; 2018; 2020 View substance registered dossier
INTERTEK FRANCE ZAC Ecoparc II 27400 HEUDEBOUVILLE France France Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
Vantage Specialty Chemicals 3 rue Jules Guesde 91130 RIS ORANGIS France France Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
SAT 1596 NUFRI Carretera de Palau Km 1 25230 Mollerussa Lérida Spain Spain Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
[Confidential] - - - (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
TAKASAGO TEPL-OR(7) 12 rue Torricelli 75017 Paris France France Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
Bell Flavors & Fragrances GmbH Schimmelstr. 1 04205 Leipzig Germany Germany Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
H. REYNAUD & FILS La Cheminade 26570 MONTBRUN LES BAINS France France Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
COINTREAU CARREFOUR MOLIERE 49124 SAINT BARTHELEMY D'ANJOU France France Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
Augustus Oils Ltd Augustus House Mill Lane GU34 2QG Alton Hampshire United Kingdom United Kingdom No longer Valid (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 2021 View substance registered dossier
Cytec Industries BV Weena 505 3013 AL Rotterdam Netherlands Netherlands Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
Globalab I+D, S.L. Avenida Visley nº 7 11407 Jerez de la Frontera Cadiz Spain Spain Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
DRT OR FOR PINOVA 30 rue Gambetta BP 206 40105 Dax France France Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
PRODALIM B.V. Binnenvenstraat 5 1911 TK Uitgeest Netherlands Netherlands Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
Kraton Chemical AB OR1 Massvagen 15 P.O. Box 66 SE-820 22 Sandarne Sweden Sweden Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 2016; 2018 View substance registered dossier
BORDAS SAS 1 Bis Rue Emile Zola L 'Algav 13170 Les Pennes Mirabeau France France Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
Claus Nitsche & Sohn GmbH Billbrookdeich 122 22113 Hamburg Germany Germany Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
PRODASYNTH PI DES BOIS DE GRASSE 4 AV. JOSEPH HONORE ISNARD 06130 GRASSE France France Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
Chemours Netherlands B.V. Baanhoekweg 22 3313 LA Dordrecht Netherlands Netherlands Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 2021 View substance registered dossier
TAKASAGO TEPL-Importer 12 rue Torricelli 75017 Paris France France Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 2020 View substance registered dossier
V. MANE FILS 620 route de Grasse 06620 Le Bar sur Loup France France Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
3M Deutschland GmbH Carl-Schurz-Strasse 1 41453 Neuss Germany Germany Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
3M Wroclaw Sp.z.o.o. ul. Kowalska 143 51-424 Wroclaw Poland Poland Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 2018 View substance registered dossier
Frey + Lau GmbH Immenhacken 12 DE-24558 Henstedt-Ulzburg Germany Germany Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 2018 View substance registered dossier
Leica Biosystems Nussloch GmbH Heidelberger Straße 17-19 69226 Nussloch Germany Germany Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
LLUCH ESSENCE, S.L.U. Lo Gaiter, 160 08820 EL PRAT DE LLOBREGAT CATALUÑA Spain Spain Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 2019 View substance registered dossier
Yordas GmbH Äußere Nürnberger Str. 6 91301 Forchheim Germany Germany Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 2019 View substance registered dossier
3M Belgium BVBA/SPRL Hermeslaan 7 1831 Diegem Belgium Belgium Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
Quimimont SLU C/ Llobregat 6, Polígono Industrial Can Bernades-Subirà 08130 Santa Perpètua de Mogoda Barcelona Spain Spain Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
Refresco Iberia S.A.U. Carretera N-332, Km. 206, 9 46780 Oliva Valencia Spain Spain Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
Intertek Deutschland GmbH 33 Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany Germany Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
IBERCHEM, S.A Polígono Industrial Oeste P.9/9 30820 ALCANTARILLA MURCIA Spain Spain Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
Weissmeer Baltische Import-Export GmbH Colonnaden 51 20354 Hamburg Germany Germany Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 2013 View substance registered dossier
ALFARIN QUIMICA, S.A. C/. Ibiza 35 -5º C 28009 MADRID Spain Spain Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 2017 View substance registered dossier
ECSA ITALIA SRL con Unico Socio Via Lav. Autobianchi, 1 I-20832 Desio (MB) Lombardia Italy Italy Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 2016 View substance registered dossier
REACHLaw Ltd. Vänrikinkuja 3 JK 21 02600 Espoo Finland Finland Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
International Flavors & Fragrances I.F.F. (Nederland) B.V. Liebergerweg 72-98 1221 JT Hilversum Netherlands Netherlands Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
ADM WILD Europe GmbH & Co. KG Rudolf-Wild-Strasse 107-115 69214 Eppelheim Baden-Württemberg Germany Germany Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
ZUMOS PALMA S.L.U. Polígono Industrial Mataché 18-53 14700 Palma del Rio Córdoba Spain Spain Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
MCI Miritz Citrus GmbH & Co. KG Citrusstraße 3 37318 Kirchgandern Germany Germany Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
CITRICOS DEL ANDEVALO S.A. Camino de Lepe, S/N 21540 Huelva Spain Spain Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
BONTOUX S.A.S. Le clôt 26170 Saint Auban sur l'Ouvèze France France Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
Associate Allied Chemicals Europe ZI DES BOIS DE GRASSE 37 AVENUE LOUISON BOBET 06130 Grasse France France Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
European Refreshments Unlimited Company Southgate Dublin Road A92 YK7W Drogheda Meath Ireland Ireland Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
KiK Textilien und Non-Food GmbH Siemensstrasse 21 59199 Boenen Germany Germany Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
IFF OR NL2 International Flavors & Fragrances I.F.F. (Nederland) B.V. Liebergerweg 72-98 1221JT Hilversum Noord-Holland Netherlands Netherlands Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
DESTILACIONES BORDAS CHINCHURRETA, S.A. C/ Acueducto, 4-6 Pol. Ind. Ctra la Isla 41703 Dos Hermanas (Sevilla) Spain Spain Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
SCAS Europe S.A./N.V. Leonardo Da Vincilaan 19 B-1831 Diegem Belgium Belgium Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 2012 View substance registered dossier
ZUMOS VALENCIANOS DEL MEDITERRÁNEO S.A. C/ del Pollancar s.n. P.I.Parc Sagunt I 46520 Sagunto Valencia Spain Spain Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 - View substance registered dossier
Bostik Nederland B.V. Zeggeveld #10 RP4705 Roosendaal Netherlands Netherlands Active (R)-p-mentha-1,8-diene 227-813-5 5989-27-5 2018 View substance registered dossier
Astellas Ireland Co.Ltd Damastown Road Damastown Industrial Park NA Mulhuddart Dublin 15 Ireland Ireland Active (R)-quinuclidin-3-ol 246-857-6 25333-42-0 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active (R)-quinuclidin-3-ol 246-857-6 25333-42-0 2017 View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active (R)-quinuclidin-3-ol 246-857-6 25333-42-0 - View substance registered dossier
JSC "Olainfarm" Rupnicu str. 5 LV-2114 Olaine Latvia Latvia Active (R)-quinuclidin-3-ol 246-857-6 25333-42-0 - View substance registered dossier
ISAGRO SpA via Caldera 21 20153 Milan Italy Italy Active (R)-thiazolidine-4-carboxylic acid 252-106-3 34592-47-7 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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