Registered substances

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.


 

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Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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(4aR,4bS,6aS,7S,7aS,8aS,8bS,8cR)-5`-methoxy-4a,6a-dimethyl-4,4`,4a,4b,5`,6,6a,7a,8,8a,8b,8c-dodecahydro-3H,3`H-spiro[cyclopropa[4,5]cyclopenta[1,2-a]phenathrene-7,2`-furan]-2(5H)-one
695-294-6 71136-60-2 Active Intermediate Joint Intermediate use only 30-04-2020 View substance registered dossier
(4aR,4bS,6aS,9aS,9bR,11aR)-4a,6a-Dimethyltetradecahydro-1H-indeno[5,4-f]quinoline-2,7-dione
616-323-0 76318-69-9 Active Intermediate Joint Intermediate use only 14-06-2016 View substance registered dossier
(4E)-4-[3-(2,5-dichloro-4,6-dimethylpyridin-3-yl)-2H-1,2,4-oxadiazol-5-ylidene]-2-methoxy-6-nitrocyclohexa-2,5-dien-1-one
941-406-6 1391712-50-7 Active Intermediate Joint Intermediate use only 08-01-2019 View substance registered dossier
(4E)-N-hydroxy-1,2-benzoxathiin-4(3H)-imine 2,2-dioxide
611-875-9 597563-86-5 Active Intermediate Joint Intermediate use only 28-10-2016 View substance registered dossier
(4R)-2-(1-butoxyethoxy)-4-isopropyl-1-methylene-cyclohexane
944-221-9 1429469-15-7 Active Intermediate Joint Intermediate use only 24-02-2017 View substance registered dossier
(4R)-2-oxo-1,3-oxazolidine-4-carboxylic acid
849-166-3 83841-00-3 Active Intermediate Joint Intermediate use only 18-05-2021 View substance registered dossier
(4R)-4-(dimethylamino)-2,2-diphenylpentanenitrile
616-258-8 7576-16-1 Active Intermediate Joint Intermediate use only 14-02-2022 View substance registered dossier
(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;N,N-diethylethanamine
926-346-0 - Active Intermediate Joint Intermediate use only 10-11-2017 View substance registered dossier
(4R,12aS)-7-Benzyloxy-N-[(2,4-difluorophenyl)methyl]-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
809-887-6 1206102-11-5 Active Intermediate Individual Intermediate use only 27-06-2019 View substance registered dossier
(4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
809-888-1 1051375-16-6 Active Intermediate Individual Intermediate use only 21-06-2017 View substance registered dossier
(4R,4aS,7aR,12bS)-3-(ethoxycarbonyl)-7-oxo-1,2,3,4,7,7a-hexahydro-4aH-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diyl diacetate
955-282-6 2387639-94-1 Active Intermediate Joint Intermediate use only 15-12-2021 View substance registered dossier
(4R,4aS,7aR,12bS)-3-methyl-7-oxo-2,3,4,4a,7,7a-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diyl diacetate
875-213-2 50798-31-7 Active Intermediate Joint Intermediate use only 03-11-2021 View substance registered dossier
(4R,4aS,7aR,12bS)-4a,9-dihydroxy-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one hemi((2R,3R)-2,3-dihydroxysuccinate)
956-466-9 - Active Intermediate Joint Intermediate use only 07-10-2022 View substance registered dossier
(4R,6R)-4-Hydroxy-2,2,6-trimethylcyclohexanone / 60046-50-6
700-052-0 60046-50-6 Active Intermediate Joint Intermediate use only 20-11-2019 View substance registered dossier
(4R,6S)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol
604-572-8 147128-77-6 Active Intermediate Joint Intermediate use only 06-09-2018 View substance registered dossier
(4S)-1-[(2S)-3-(benzoylthio)-2-methyl-1-oxopropyl]-4-(phenylthio)-L-proline potassium salt
617-274-8 81938-42-3 Active Intermediate Individual Intermediate use only 09-10-2015 View substance registered dossier
(4S)-2-(4-bromophenyl)-4-isopropyl-3-pentanoyl-1,3-oxazolidin-5-one
700-586-4 852212-81-8 Active Intermediate Individual Intermediate use only 10-05-2011 View substance registered dossier
(4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone
848-798-7 272778-12-8 Active Intermediate Joint Intermediate use only 15-06-2020 View substance registered dossier
(4S)-3-carbamoyl-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridin-1-ium (2S,3S)-2,3-bis(benzoyloxy)-3-carboxypropanoate
947-346-7 - Active Intermediate Individual Intermediate use only 03-01-2023 View substance registered dossier
(4S)-4-(2-Chlorophenyl)-2-hydroxy-5,5-dimethyl-1,3,2-dioxaphosphinane 2-oxide
623-314-5 98674-86-3 Active Intermediate Joint Intermediate use only 26-03-2018 View substance registered dossier
(4S)-4-(3,4-dichlorophenyl)-N-methyl-tetralin-1-imine
811-284-8 312620-93-2 Active Intermediate Joint Intermediate use only 02-06-2016 View substance registered dossier
(4S)-4-(phenylsulfanyl)-L-proline
617-252-8 81653-77-2 Active Intermediate Joint Intermediate use only 13-10-2021 View substance registered dossier
(4S)-4-amino-5-benzyloxy-5-oxo-pentanoic acid
692-605-7 13030-09-6 Active Intermediate Individual Intermediate use only 13-07-2022 View substance registered dossier
(4S)-4-cyclohexyl-L-proline
600-406-3 103201-78-1 Active Intermediate Individual Intermediate use only 24-02-2010 View substance registered dossier
(4S)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4,4a,7a-tetrahydrothieno[3,2-e]thiazine-6-sulfonamide
807-123-6 154127-42-1 No longer Valid Intermediate Individual No longer valid 29-05-2018 View substance registered dossier
(4S)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4,4a,7a-tetrahydrothieno[3,2-e]thiazine-6-sulfonamide
807-123-6 154127-42-1 Active Intermediate Joint Intermediate use only 23-03-2022 View substance registered dossier
(4S,4aR,5aR,6R,6aR,6bS,7S,9aS,11aS,11bR)-6-hydroxy-9a,11b-dimethyl-9-oxohexadeca hydrocyclopenta[1,2]phenanthro[8a,9-b]oxirene-4,7-diyl bis(2,2-dimethylpropanoate)
825-705-8 1235460-56-6 Active Intermediate Joint Intermediate use only 17-07-2018 View substance registered dossier
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12aoctahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1)
940-053-5 - Active Intermediate Joint Intermediate use only 19-01-2017 View substance registered dossier
(4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide
617-177-0 808-26-4 Active Intermediate Joint Intermediate use only 13-09-2018 View substance registered dossier
(4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-7-[[methoxy(methyl)amino]methyl]-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide
811-441-0 1035654-66-0 Active Intermediate Joint Intermediate use only 27-11-2019 View substance registered dossier
(4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide dihydrochloride
611-780-2 59046-78-5 Active Intermediate Individual Intermediate use only 14-05-2018 View substance registered dossier
(4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide; 4-chlorobenzene-1-sulfonic acid
618-775-4 916439-93-5 Active Intermediate Joint Intermediate use only 22-12-2017 View substance registered dossier
(4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide p-toluenesulfonate
947-931-7 - Active Intermediate Individual Intermediate use only 24-05-2018 View substance registered dossier
(4S,4aS,5aR,12aS)-9-amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride (1:1)
604-710-7 149934-21-4 Active Intermediate Joint Intermediate use only 12-08-2019 View substance registered dossier
(4S,4aS,5aS,6S,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide di(4-chlorobenzenesulfonic acid)
925-915-0 - Active Intermediate Individual Intermediate use only 24-05-2018 View substance registered dossier
(4S,6S)-4H-Thieno[2,3-b]thiopyran-2-sulfonyl chloride, 4-(acetylethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide,
824-717-0 403848-30-6 Active Intermediate Joint Intermediate use only 05-06-2018 View substance registered dossier
(4S,6S)-5,6-dihydro-4-[ethylamin-N-(2-nitrobenzenesulfonic)]-6-methyl-4H-thieno(2,3-b)thiopyran-7,7-dioxide
947-800-4 - Active Intermediate Joint Intermediate use only 21-06-2018 View substance registered dossier
(4S-trans)-N-(5,6-diidro-6-metil-7,7-diossido-4Htieno[2,3-b]tiopiran-4-il)-acetammide
604-558-1 147086-83-7 Active Intermediate Joint Intermediate use only 09-03-2018 View substance registered dossier
(4Z)-3-ammoniomethyl-4-(methoxyimino)pyrrolidinium dimethanesulfonate
608-799-3 329181-36-4 Active Intermediate Individual Intermediate use only 10-06-2009 View substance registered dossier
(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid
700-141-4 117570-53-3 Cease Manufacture Intermediate Individual Cease manufacture 22-06-2010 View substance registered dossier
(5-Bromo-2-chloro-phenyl)-(4-ethoxy-phenyl)-methanone
630-623-9 461432-22-4 Active Intermediate Joint Intermediate use only 04-06-2021 View substance registered dossier
(5-bromo-2-chloro-pyrimidin-4-yl)-cyclopentylamine
800-067-3 733039-20-8 Active Intermediate Individual Intermediate use only 13-01-2017 View substance registered dossier
(5-bromothiophen-2-yl)-phenylmethanone
608-584-4 31161-46-3 Active Intermediate Joint Intermediate use only 14-02-2018 View substance registered dossier
(5-chloro-2-methoxyphenyl)boronic acid
923-256-3 - Active Intermediate Individual Intermediate use only 27-04-2018 View substance registered dossier
(5-ethyl-2-trimethylsilyloxypyrimidin-4-yl)oxy-trimethylsilane
608-586-5 31167-05-2 Active Intermediate Joint Intermediate use only 25-07-2019 View substance registered dossier
(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-{[2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylate
604-437-3 144690-92-6 Active Intermediate Joint Intermediate use only 13-05-2013 View substance registered dossier
(5E)-9-(dichloromethylidene)-N-hydroxy-2,3,4,6,7,8-hexahydro-1,4-methanonaphthalen-5(1H)-imine
700-700-2 - Active Intermediate Joint Intermediate use only 30-09-2022 View substance registered dossier
(5E,9E,13E)-6,10,14,18-tetramethylnonadeca-5,9,13,17-tetraen-2-one
614-276-0 6809-52-5 Active Intermediate Joint Intermediate use only 16-10-2018 View substance registered dossier
(5R)-3-(3,4-difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)furan-2-one
957-069-3 2875066-35-4 Active Intermediate Joint Intermediate use only 23-03-2023 View substance registered dossier
(5R,6S)-allyl 6-((R)-1-(tert-butyldimethylsilyloxy)ethyl)-7-oxo-3-(propylthio)-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
820-260-6 93603-76-0 Active Intermediate Joint Intermediate use only 28-06-2018 View substance registered dossier
(5R,8R,9R,10S,13S,14S)-13-methyl-1,2,4,5,6,7,8,9,10,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthrene-3,17-dione
881-231-1 5696-51-5 Active Intermediate Joint Intermediate use only 28-07-2022 View substance registered dossier
(5S)-1,2,3,4-tetra-O-acetyl-5-[4-chloro-3-(4-ethoxybenzyl)phenyl]-beta-L-xylopyranose
815-962-4 1384242-56-1 Active Intermediate Joint Intermediate use only 04-12-2019 View substance registered dossier
(5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-ol
879-204-4 1373116-05-2 Active Intermediate Joint Intermediate use only 04-02-2022 View substance registered dossier
(5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate
880-367-9 1289023-67-1 Active Intermediate Joint Intermediate use only 25-02-2022 View substance registered dossier
(5S,6S,9R)-6-(2,3-difluorophenyl)-9-((triisopropylsilyl)oxy)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-aminedihydrochloride
874-683-6 1373116-04-1 Active Intermediate Joint Intermediate use only 15-10-2021 View substance registered dossier
(5Z)-5-(2-methylpropylidene)imidazolidine-2,4-dione
700-726-4 - Active Intermediate Joint Intermediate use only 02-02-2022 View substance registered dossier
(5Z)-5-benzylideneimidazolidine-2,4-dione
700-728-5 74805-60-0 Active Intermediate Joint Intermediate use only 25-02-2022 View substance registered dossier
(5Z)-6,10-dimethylundeca-5,9-dien-2-one
626-253-2 3879-26-3 Active Intermediate Joint Intermediate use only 17-03-2022 View substance registered dossier
(5´R,8´S,10´R,13´S,14´S)-13´-methyl-1´,2´,6´,7´8´,12´,13´,14´,15´,16´-decahydro-17´H-spiro[1,3-dioxolane-2,3´-[5,10]epoxycyclopenta[a]phenantren]-17´-one
821-898-8 39931-87-8 Active Intermediate Joint Intermediate use only 07-05-2020 View substance registered dossier
(5α)-4,5-epoxy-14-hydroxy-3-methoxymorphinan-6-one
260-887-7 57664-96-7 Active Intermediate Joint Intermediate use only 28-04-2017 View substance registered dossier
(5α)-4,5-epoxy-17-methyl-6-oxomorphinan-3,14-diyl diacetate
264-989-2 64643-76-1 Active Intermediate Individual Intermediate use only 03-12-2018 View substance registered dossier
(5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
251-561-5 33522-95-1 Active Intermediate Joint Intermediate use only 16-09-2022 View substance registered dossier
(5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride
257-924-4 52446-24-9 Active Intermediate Joint Intermediate use only 16-03-2017 View substance registered dossier
(5α)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol
207-385-6 467-04-9 Active Intermediate Joint Intermediate use only 29-06-2022 View substance registered dossier
(5α)-7,8-didehydro-4,5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
208-085-8 508-54-3 No longer Valid Intermediate Joint No longer valid 15-03-2018 View substance registered dossier
(5α)-7,8-didehydro-4,5-epoxy-3,14-dihydroxymorphinan-6-one
282-186-5 84116-46-1 No longer Valid Intermediate Joint No longer valid 12-07-2019 View substance registered dossier
(5α,6α)-17-(cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol hydrochloride
245-549-9 23277-43-2 Active Intermediate Joint Intermediate use only 19-06-2017 View substance registered dossier
(6-amino-2-pyridyl)-(1-methyl-4-piperidyl)methanone;dihydrate;dihydrochloride
842-055-0 2356133-42-9 Active Intermediate Individual Intermediate use only 21-08-2019 View substance registered dossier
(6-hydroxynaphthalen-2-yl)boronic acid
687-349-8 173194-95-1 Active Intermediate Individual Intermediate use only 21-12-2015 View substance registered dossier
(6-morpholin-4-ylpyrimidin-4-yl)hydrazine
691-196-2 5767-36-2 Active Intermediate Individual Intermediate use only 25-08-2014 View substance registered dossier
(6a,8xi,11b,14xi,16a)-6,9-difluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4- dien-21-yl benzoate
938-716-9 - No longer Valid Intermediate Individual No longer valid 04-02-2013 View substance registered dossier
(6ALPHA,11BETA,16ALPHA,17ALPHA)-6,9-DIFLUORO-11-HYDRO XY-16-METHYL-3-OXO-17- (1-OXOPROPOXY)ANDROSTA-1,4-DIENE-CARBOTHIOIC ACID
617-084-5 80474-45-9 Active Intermediate Joint Intermediate use only 29-07-2022 View substance registered dossier
(6R)-6-(dimethylamino)-4,4-diphenylheptan-3-one
603-081-6 125-58-6 Active Intermediate Joint Intermediate use only 14-02-2022 View substance registered dossier
(6R)-6-Dimethylamino-4,4-diphenyl-heptan-3-one; compound with 2-(toluene-4-sulfonylamino)-pentanedioic acid
921-925-4 - Active Intermediate Joint Intermediate use only 14-02-2022 View substance registered dossier
(6R*,7R*)-7-hydroxy-6-[(propan-2-yl)amino]-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one
862-404-0 119520-05-7 Active Intermediate Joint Intermediate use only 24-08-2022 View substance registered dossier
(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)
939-998-6 - Cease Manufacture Intermediate Joint Cease manufacture 24-11-2014 View substance registered dossier
(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)
939-998-6 - Active Intermediate Individual Intermediate use only 18-12-2013 View substance registered dossier
(6R,7R)-3-chloromethyl-7-{(Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)2-[(1-carboxy-1-methylethoxy)imino]acetylamino}-8-oxo-5-thia-1-azbicyclo[4.2.0]oct-2-ene-2-carboxylic acid p-methoxybenzyl ester
939-996-5 689294-28-8 Active Intermediate Joint Intermediate use only 08-04-2014 View substance registered dossier
(6R,7R)-3-chloromethyl-7-{(Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)2-[(1-carboxy-1-methylethoxy)imino]acetylamino}-8-oxo-5-thia-1-azbicyclo[4.2.0]oct-2-ene-2-carboxylic acid p-methoxybenzyl ester
939-996-5 689294-28-8 Active Intermediate Individual Intermediate use only 26-02-2014 View substance registered dossier
(6R,7R)-7-[[(2Z)-(2-Aminothiazol-4-yl)(methoxy-imino)acetyl]amino]-3-[1-methylpyrrolidinio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate dihydrochloride
827-945-9 107648-80-6 Active Intermediate Joint Intermediate use only 21-09-2018 View substance registered dossier
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[2-methyl-1-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
600-349-4 102772-66-7 Active Intermediate Joint Intermediate use only 08-05-2018 View substance registered dossier
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrochloride
600-507-2 103980-44-5 Cease Manufacture Intermediate Joint Cease manufacture 03-04-2018 View substance registered dossier
(6R,7R)-7-amino-3-(5H-imidazo[1,2-b]pyridazin-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydroiodide
606-382-0 197897-11-3 Cease Manufacture Intermediate Individual Cease manufacture 20-04-2018 View substance registered dossier
(6R,7R)-7-amino-3-{[(furan-2-ylcarbonyl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
617-065-1 80370-59-8 Cease Manufacture Intermediate Joint Cease manufacture 03-04-2018 View substance registered dossier
(6R,7R)-7-Amino-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4,2,0]oct-2-ene-2-carboxylic acid
438-350-5 79349-82-9 Active Intermediate Joint Intermediate use only 21-12-2017 View substance registered dossier
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
700-301-3 69739-16-8 Cease Manufacture Intermediate Individual Cease manufacture 04-06-2009 View substance registered dossier
(6R,7R)-benzhydryl 3-hydroxy-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
611-177-4 54639-48-4 Active Intermediate Joint Intermediate use only 03-06-2013 View substance registered dossier
(6R,7R,14S)-17-cyano-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethano-17-normorphine
921-415-1 - Active Intermediate Individual Intermediate use only 01-09-2016 View substance registered dossier
(6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethanomorphine
918-453-6 - Active Intermediate Individual Intermediate use only 31-08-2016 View substance registered dossier
(6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-6-O-methyl-6,14-ethano-17-normorphine
917-585-1 - Active Intermediate Individual Intermediate use only 01-09-2016 View substance registered dossier
(6R,7S)-Benzhydryl 7-amino-7-methoxy-3-((1-methyl-1H-tetrazol-5-ylthio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
611-404-7 56610-72-1 Active Intermediate Joint Intermediate use only 02-11-2016 View substance registered dossier
(6R-trans)-7-amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
239-787-2 15690-38-7 Active Intermediate Joint Intermediate use only 19-12-2018 View substance registered dossier
(6R-trans)-7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
250-099-1 30246-33-4 Active Intermediate Joint Intermediate use only 16-10-2019 View substance registered dossier
(6R-trans)-7-amino-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
619-847-8 111298-82-9 Cease Manufacture Intermediate Individual Cease manufacture 26-03-2009 View substance registered dossier
(6R-trans)-7-amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
258-907-4 53994-69-7 Active Intermediate Joint Intermediate use only 16-10-2019 View substance registered dossier
(6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
244-870-1 22252-43-3 Active Intermediate Joint Intermediate use only 16-12-2019 View substance registered dossier
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
261-491-7 58909-56-1 Active Intermediate Joint Intermediate use only 10-07-2019 View substance registered dossier
(6S)-1'-tert-butyl-3-chlorospiro[5,7-dihydrocyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-2'-one
881-148-0 1455358-14-1 Active Intermediate Joint Intermediate use only 14-03-2022 View substance registered dossier
(6S)-2,6-dimethyloct-2-ene-8,8-diyl diacetate
949-377-1 - Active Intermediate Joint Intermediate use only 10-05-2019 View substance registered dossier
(6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide
431-140-4 - Active Intermediate Joint Intermediate use only 13-11-2017 View substance registered dossier
(6S,12aR)-3,10-Dibromo-12,12a-dihydro-6-phenyl-6H-indolo[1,2-c][1,3]benzoxazine
813-155-1 1585969-16-9 Active Intermediate Individual Intermediate use only 21-09-2016 View substance registered dossier
(6S,8S,9S,10R,11S,13S,14S,17R)-17-acetyl-11,17-dihydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
615-123-0 7055-53-0 Active Intermediate Joint Intermediate use only 28-01-2022 View substance registered dossier
(6S,9R,10S,11S,13S,14S,16R,17R)-17-(((diethylamino)(ethyl)-λ4-sulfaneyl)carbonyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[α]phenanthren-17-yl propionate
884-371-1 577970-31-1 Active Intermediate Joint Intermediate use only 29-07-2022 View substance registered dossier
(6S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(propionyloxy)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid
813-979-1 65429-42-7 Active Intermediate Joint Intermediate use only 29-07-2022 View substance registered dossier
(6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid
434-320-0 - Active Intermediate Joint Intermediate use only 08-10-2021 View substance registered dossier
(6Z)-6-(hydroxyimino)-5,6-dihydroimidazo[4,5,1-jk][1]benzazepine-2,7(1H,4H)-dione
695-945-4 - Active Intermediate Joint Intermediate use only 23-06-2022 View substance registered dossier
(7-Bromobenzofuran-5-yl)methanol
876-095-5 286836-24-6 Active Intermediate Joint Intermediate use only 24-02-2022 View substance registered dossier
(7-methoxynaphthalen-1-yl)acetonitrile
461-670-1 - Active Intermediate Joint Intermediate use only 14-12-2021 View substance registered dossier
(7-Phenylsulfonyl-6-nitro-chinazolin-4-yl)-(3-chlor-4-fluor-phenyl)-amin
620-069-6 945553-94-6 Active Intermediate Joint Intermediate use only 26-04-2018 View substance registered dossier
(7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate
642-947-8 415927-29-6 Active Intermediate Individual Intermediate use only 04-04-2018 View substance registered dossier
(7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate and (7S,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6, 7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate
943-624-7 - Active Intermediate Joint Intermediate use only 01-03-2022 View substance registered dossier
(7R,8R,9S,13S,14S,17S)-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[α]phenanthrene-3,17-diol
642-948-3 153004-31-0 Active Intermediate Joint Intermediate use only 30-11-2021 View substance registered dossier
(7S,8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[α]phenanthren-6-one
837-287-4 1107606-70-1 Active Intermediate Joint Intermediate use only 30-11-2021 View substance registered dossier
(7S,8R,9S,13S,14S,17S)-7-(9-chlorononyl)-3,17-dihydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-6-one
955-019-5 - Active Intermediate Joint Intermediate use only 22-10-2021 View substance registered dossier
(7S,9aS)-7-[(benzyloxy)methyl]octahydropyrazino[2,1-c][1,4]oxazine dioxalic acid salt
875-887-8 1268364-46-0 Active Intermediate Joint Intermediate use only 23-02-2022 View substance registered dossier
(8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione - 2,3,5,6-tetrachlorobenzene-1,4-diol (1:1)
926-987-6 - Active Intermediate Joint Intermediate use only 13-12-2021 View substance registered dossier
(8R,9S,10R,13S,14S,17R)-17-ethynyl-10,13-dimethyl-1,2,4,7,8,9,10,11,12,13,14,15,16,17,-tetradecahydrospiro[cyclopenta[a]phenanthrene-3,2´-[1,3]dioxolan]-17-ol
610-527-3 50407-76-6 Active Intermediate Joint Intermediate use only 06-05-2020 View substance registered dossier
(8R,9S,13S,14S)-3-(Benzyloxy)-13-methyl-6,7,8,9,11,12,13,14 ,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,2`-[1,3]dioxolane]
844-245-9 162784-26-1 Active Intermediate Individual Intermediate use only 09-11-2021 View substance registered dossier
(8R,9S,13S,14S)-3-benzyloxy)-13-methyl-6,7,8,9,11,12,13,14- octahydrospiro[cyclopenta[a]phenanthrene-17,2`[1,3]dioxolane]
844-243-8 534572-67-3 Active Intermediate Individual Intermediate use only 05-11-2021 View substance registered dossier
(8R,9S,13S,14S,17S)-3,17-bis((2-methoxypropan-2-yl)oxy)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[α]phenanthren-6-one
875-633-6 486999-08-0 Active Intermediate Joint Intermediate use only 12-11-2021 View substance registered dossier
(8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-8,9,11,12,14,15,16,17-octahydro-7H-cyclopenta[a]phenanthren-6-one
641-994-1 571-92-6 Active Intermediate Joint Intermediate use only 01-04-2020 View substance registered dossier
(8S,10S,13S,14S,17R)-17-hydroxy-10,13-dimethyl-1,2,4,7,8,10,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolane]-17-carbonitrile
601-332-4 114882-16-5 Active Intermediate Joint Intermediate use only 25-01-2022 View substance registered dossier
(8S,13S,14S,17R)-17-allyl-13-methyl-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-17ol
849-739-8 141299-95-8 Active Intermediate Joint Intermediate use only 13-04-2021 View substance registered dossier
(8S,13S,14S,17R)-17-allyl-17-hydroxy-13-methyl-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
849-749-2 23760-34-1 Active Intermediate Joint Intermediate use only 13-04-2021 View substance registered dossier
(8S,13S,14S,17S)-17-hydroxy-13-methyl-2,6,7,8,14,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-3-one
600-229-1 10161-33-8 Active Intermediate Joint Intermediate use only 07-02-2022 View substance registered dossier
(8~{S},13~{S},14~{S})-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione
610-717-6 5173-46-6 Active Intermediate Joint Intermediate use only 21-02-2019 View substance registered dossier
(9beta,11beta)-3,20-dioxo-9,11-epoxypregna-1,4,16-trien-21-yl acetate
600-439-3 103466-44-0 Active Intermediate Joint Intermediate use only 25-01-2022 View substance registered dossier
(9H-fluoren-9-yl)methyl (2,5-dioxopyrrolidin-1-yl) carbonate
433-520-5 82911-69-1 Active Intermediate Joint Intermediate use only 29-11-2022 View substance registered dossier
(9R,10S,13S)-10,13-dimethyl-17-(2-methyl-1,3-dioxolan-2-yl)spiro[1,2,4,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,2'-1,3-dioxolane]
611-207-6 5488-51-7 Active Intermediate Joint Intermediate use only 19-11-2018 View substance registered dossier
(9β,11β,16α)-9,11-epoxy-21-hydroxy-16, 17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione
609-736-2 39672-75-8 Active Intermediate Individual Intermediate use only 30-05-2014 View substance registered dossier
(alpha-cyanobenzyl)malonic acid diethyl ester
922-463-6 - Active Intermediate Joint Intermediate use only 17-02-2017 View substance registered dossier
(alphaS)-methyl alpha-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetate 2-propyl sulfate
614-478-9 684269-94-1 Active Intermediate Joint Intermediate use only 15-09-2021 View substance registered dossier
(Bromomethyl)cyclobutane
700-027-4 17247-58-4 Cease Manufacture Intermediate Individual Cease manufacture 31-08-2011 View substance registered dossier
(Bromomethyl)cyclobutane
700-027-4 17247-58-4 Cease Manufacture Intermediate Joint Cease manufacture 14-12-2011 View substance registered dossier
(Bromomethylphenyl-4')-2 benzonitrile
601-327-7 114772-54-2 Active Intermediate Joint Intermediate use only 31-05-2013 View substance registered dossier
(chloromethyl)cyclopropane
227-632-1 5911-08-0 Active Intermediate Individual Intermediate use only 29-03-2018 View substance registered dossier
(Chloromethyl)dimethoxymethylsilane
606-938-2 2212-11-5 Active Intermediate Individual Intermediate use only 17-01-2022 View substance registered dossier
(Chloromethyl)methoxydimethylsilane
700-268-5 18143-33-4 Active Intermediate Individual Intermediate use only 09-07-2008 View substance registered dossier
(Chloromethyl)trimethoxysilane
611-813-0 5926-26-1 Active Intermediate Individual Intermediate use only 18-02-2011 View substance registered dossier
(cis)-4-[2-[2-((1S,2S,5S)-6,6-dimethylnorpinan-2-yl)ethoxy]ethyl]morpholine
700-519-9 - Active Intermediate Joint Intermediate use only 13-01-2020 View substance registered dossier
(cyclopropylmethoxy)acetic acid
853-795-9 246869-08-9 Active Intermediate Individual Intermediate use only 18-03-2021 View substance registered dossier
(Diethoxyphosphoryl)acetate
608-560-3 3095-95-2 Active Intermediate Joint Intermediate use only 06-05-2015 View substance registered dossier
(diethylamino)acetonitrile
221-130-6 3010-02-4 Active Intermediate Joint Intermediate use only 28-02-2018 View substance registered dossier
(dimethoxy(methyl)silyl)methanamine
812-377-6 343926-26-1 Active Intermediate Joint Intermediate use only 01-02-2019 View substance registered dossier
(E)- 1-(4-Methylsubstitutedphenyl-3-(3,5-dimethylaryl)propenone
- - Active Intermediate Joint Intermediate use only 21-09-2021 View substance registered dossier
(E)-(4-methoxy-2,3,6-trimethylphenyl)-3-buten-2-one
263-760-4 62924-31-6 Active Intermediate Joint Intermediate use only 18-05-2018 View substance registered dossier
(E)-(5,6-dihydro-1,4,2-dioxazin-3-yl)(2-hydroxyphenyl)methanone O-methyloxime
456-110-8 - Active Intermediate Joint Intermediate use only 06-04-2022 View substance registered dossier
(E)-(6,10-dimethylundeca-1,5,9-trien-2-yl)cyclopropane
834-085-8 714230-50-9 Active Intermediate Individual Intermediate use only 15-02-2022 View substance registered dossier
(E)-1,3-dichloropropene 431-460-4 10061-02-6 Active Intermediate Joint Intermediate use only 16-09-2021 View substance registered dossier
(E)-1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]pyrimidine citrate (1:1)
227-154-3 5685-86-9 Active Intermediate Joint Intermediate use only 12-03-2018 View substance registered dossier
(E)-1,4-dibromobut-2-ene
212-472-7 821-06-7 Cease Manufacture Intermediate Joint Cease manufacture 18-05-2018 View substance registered dossier
(E)-1-(4-methylthiophenyl)-3-(3,5-dimethyl-4-tertbutyloxycarbonyldimethylmethylhydroxyphenyl)prop-2-en-1-one
- - Active Intermediate Joint Intermediate use only 21-09-2021 View substance registered dossier
(E)-1-methoxyprop-1-ene
615-927-1 7319-16-6 Active Intermediate Joint Intermediate use only 05-03-2020 View substance registered dossier
(E)-1-propene-1,2,3-tricarboxylic acid
223-688-6 4023-65-8 Active Intermediate Joint Intermediate use only 12-11-2020 View substance registered dossier
(E)-2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-ylmethylene)-5,6-dimethoxy-indan-1-one hydrochloride
940-983-1 - Active Intermediate Individual Intermediate use only 03-12-2014 View substance registered dossier
(E)-2-(2-(4-dibenzo[b,f][1,4]thiazepin-11-yl)piperazin- 1-yl)ethoxy)ethanol hydrochloride
696-107-0 930086-71-8 Active Intermediate Individual Intermediate use only 22-04-2013 View substance registered dossier
(E)-2-chloro-N-[4-chloro-2-[(hydroxyimino)phenylmethyl]phenyl]acetamide
220-755-1 2888-63-3 Active Intermediate Joint Intermediate use only 24-07-2017 View substance registered dossier
(E)-2-Ethoxy-N-(2-methyl-1-phenylpropylidene)ethylamine
604-106-3 139007-06-0 Active Intermediate Joint Intermediate use only 14-05-2013 View substance registered dossier
(E)-2-methyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)but-2-en-1-ol
813-338-6 106155-02-6 Active Intermediate Joint Intermediate use only 06-06-2017 View substance registered dossier
(E)-2-methyl-4-phenylpent-2-enal
618-755-5 91495-55-5 Active Intermediate Joint Intermediate use only 12-07-2018 View substance registered dossier
(E)-2-methylpent-2-enenitrile
250-694-6 31551-28-7 Active Intermediate Joint Intermediate use only 01-12-2017 View substance registered dossier
(E)-3,5-dimethylhex-3-en-2-one
606-014-9 18402-86-3 Active Intermediate Joint Intermediate use only 06-06-2017 View substance registered dossier
(E)-3,7,11-trimethyldodeca-1,6,10-trien-3-ol
255-053-4 40716-66-3 Active Intermediate Joint Intermediate use only 02-12-2019 View substance registered dossier
(E)-3,7-dimethylocta-2,6-dienal
205-476-5 141-27-5 Active Intermediate Joint Intermediate use only 14-06-2016 View substance registered dossier
(E)-3-(4-isobutylphenyl)-2-methylacrylaldehyde
824-059-4 2147744-66-7 Active Intermediate Joint Intermediate use only 13-10-2021 View substance registered dossier
(E)-3-[6-(p-toluoyl)-2-pyridyl]acrylic acid
302-128-5 94094-27-6 No longer Valid Intermediate Individual No longer valid 22-10-2018 View substance registered dossier
(E)-3-formylbut-2-enyl acetate
247-825-4 26586-02-7 Active Intermediate Joint Intermediate use only 11-05-2016 View substance registered dossier
(E)-3-Methyl-4-oxo-but-2-enoic acid ethylester
690-663-8 62054-49-3 Active Intermediate Joint Intermediate use only 06-02-2023 View substance registered dossier
(E)-3-methylpent-2-en-4-yn-1-ol
228-169-8 6153-06-6 Active Intermediate Joint Intermediate use only 05-03-2020 View substance registered dossier
(E)-3-phenylprop-2-enal
604-377-8 14371-10-9 Active Intermediate Joint Intermediate use only 09-11-2021 View substance registered dossier
(E)-4-Dimethylamino-but-2-enoic acid [4-(3-chloro-4-fluoro-phenyl-amino)-7-((S)-(tetrahydrofuran-3-yl)oxy)-quinazoline-6-yl]-amide
923-981-5 - Active Intermediate Joint Intermediate use only 17-02-2023 View substance registered dossier
(E)-4-Ethoxy-1,1,1-trifluoro-3-buten-2-one (stabilized with BHT)
475-900-3 - Active Intermediate Individual Intermediate use only 10-12-2019 View substance registered dossier
(E)-5-(3-bromophenyl)pent-4-enoic acid
881-198-3 1180670-58-9 Active Intermediate Joint Intermediate use only 22-04-2022 View substance registered dossier
(E)-5-benzyl-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-N-nitro-1,3,5-triazinan-2-imine
606-753-7 213967-55-6 Cease Manufacture Intermediate Individual Cease manufacture 15-12-2010 View substance registered dossier
(E)-5[(4-chlorophenyl)methylene]-2,2-dimethylcyclopentanone
DMBCP
410-440-9 164058-20-2 Active Intermediate Joint Intermediate use only 14-02-2011 View substance registered dossier
(E)-6,10-dimethylundeca-5,9-dien-2-one
223-269-8 3796-70-1 Active Intermediate Joint Intermediate use only 07-10-2021 View substance registered dossier
(E)-ethyl 4-(dimethylamino)but-2-enoate maleate
941-772-7 - Active Intermediate Joint Intermediate use only 02-06-2015 View substance registered dossier
(E)-ethyl N-4-nitrophenoxyacetimidate
617-436-8 83077-00-3 Active Intermediate Joint Intermediate use only 21-01-2021 View substance registered dossier
(E)-heptan-2-one oxime
610-969-7 5314-31-8 Active Intermediate Joint Intermediate use only 10-01-2017 View substance registered dossier
(E)-methyl 2-acetyloct-2-enoate
807-427-9 228114-02-1 Cease Manufacture Intermediate Joint Cease manufacture 16-10-2014 View substance registered dossier
(E)-N'-(2-cyano-4-(3-(1-hydroxy-2-methylpropan-2-yl)thioureido)phenyl)-N,N-dimethylformimidamide
814-560-6 1429755-57-6 Active Intermediate Joint Intermediate use only 25-06-2019 View substance registered dossier
(E)-N'-hydroxy-N-(4-hydroxypyrid-2-yl)formimidamide
952-647-1 - Active Intermediate Joint Intermediate use only 01-07-2020 View substance registered dossier
(E)-N-((dialkylamino)alkylene)-3,5-bis(polyfluoroalkyl)benzamide
- - Active Intermediate Individual Intermediate use only 08-11-2016 View substance registered dossier
(E)-non-3-en-2-one
813-141-5 18402-83-0 Active Intermediate Individual Intermediate use only 07-11-2016 View substance registered dossier
(E,E)-2,6-bis[1-((2-terbutylphenyl)imino)ethyl]pyridine
881-335-7 253797-84-1 Active Intermediate Joint Intermediate use only 16-06-2022 View substance registered dossier
(E,E)-3,7,11,15-tetramethylhexadeca-1,6,10,14-tetraen-3-ol
214-201-8 1113-21-9 Active Intermediate Joint Intermediate use only 23-08-2018 View substance registered dossier
(E,E)-[5-(4-methoxy-2,3,6-trimethylphenyl)-3-methyl-2,4-pentadienyl]triphenylphosphonium chloride
273-975-5 69365-97-5 Active Intermediate Joint Intermediate use only 30-04-2019 View substance registered dossier
(E,E)-hexa-2,4-dien-1-ol
241-173-4 17102-64-6 Active Intermediate Joint Intermediate use only 16-12-2022 View substance registered dossier
(E,E,E)-2,7-dimethylocta-2,4,6-trienedial
225-756-0 5056-17-7 Active Intermediate Joint Intermediate use only 19-02-2019 View substance registered dossier
(epoxyethyl)benzene
202-476-7 96-09-3 Active Intermediate Joint Intermediate use only 11-04-2018 View substance registered dossier
(hydroxymethyl)phosphonic acid
220-047-2 2617-47-2 Active Intermediate Joint Intermediate use only 25-01-2018 View substance registered dossier
(isobutoxymethyl)oxirane
223-303-1 3814-55-9 Active Intermediate Joint Intermediate use only 23-05-2018 View substance registered dossier
(isopropyl (1s,3s)-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclobutane-1-carboxylate)
950-860-4 - Active Intermediate Joint Intermediate use only 04-05-2021 View substance registered dossier
(methoxymethyl)triphenylphosphonium chloride
223-664-5 4009-98-7 Active Intermediate Joint Intermediate use only 02-08-2019 View substance registered dossier
(methoxymethyl)triphenylphosphonium chloride
223-664-5 4009-98-7 Active Intermediate Individual Intermediate use only 16-09-2013 View substance registered dossier
(N,N-diethylaniline)trihydroboron
236-305-2 13289-97-9 Active Intermediate Joint Intermediate use only 14-06-2017 View substance registered dossier
(N-(2-methyl-1-phenyl-2 propanyl) acetamide
611-254-2 5531-33-9 Active Intermediate Joint Intermediate use only 26-04-2018 View substance registered dossier
(N-phenylcarbamimidoyl)ammonium carbonate hydrate
485-350-6 - Active Intermediate Individual Intermediate use only 19-08-2019 View substance registered dossier
(N-phenylcarbamimidoyl)ammonium carbonate hydrate
485-350-6 - Active Intermediate Individual Intermediate use only 21-12-2018 View substance registered dossier
(n-{(1s,3s)-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide hydrochloride)
952-248-2 - Active Intermediate Joint Intermediate use only 18-12-2020 View substance registered dossier
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Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (4aR,4bS,6aS,7S,7aS,8aS,8bS,8cR)-5`-methoxy-4a,6a-dimethyl-4,4`,4a,4b,5`,6,6a,7a,8,8a,8b,8c-dodecahydro-3H,3`H-spiro[cyclopropa[4,5]cyclopenta[1,2-a]phenathrene-7,2`-furan]-2(5H)-one 695-294-6 71136-60-2 2020 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (4aR,4bS,6aS,9aS,9bR,11aR)-4a,6a-Dimethyltetradecahydro-1H-indeno[5,4-f]quinoline-2,7-dione 616-323-0 76318-69-9 - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active (4E)-4-[3-(2,5-dichloro-4,6-dimethylpyridin-3-yl)-2H-1,2,4-oxadiazol-5-ylidene]-2-methoxy-6-nitrocyclohexa-2,5-dien-1-one 941-406-6 1391712-50-7 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (4E)-4-[3-(2,5-dichloro-4,6-dimethylpyridin-3-yl)-2H-1,2,4-oxadiazol-5-ylidene]-2-methoxy-6-nitrocyclohexa-2,5-dien-1-one 941-406-6 1391712-50-7 - View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active (4E)-N-hydroxy-1,2-benzoxathiin-4(3H)-imine 2,2-dioxide 611-875-9 597563-86-5 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (4R)-2-(1-butoxyethoxy)-4-isopropyl-1-methylene-cyclohexane 944-221-9 1429469-15-7 - View substance registered dossier
CABB Oy Kemirantie 1 FI-67701 Kokkola Finland Finland Active (4R)-2-oxo-1,3-oxazolidine-4-carboxylic acid 849-166-3 83841-00-3 2020 View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa - Attiki Greece Greece Active (4R)-2-oxo-1,3-oxazolidine-4-carboxylic acid 849-166-3 83841-00-3 2021 View substance registered dossier
EUROAPI Germany GmbH Brüningstraße 50 65926 Frankfurt am Main Germany Germany Active (4R)-4-(dimethylamino)-2,2-diphenylpentanenitrile 616-258-8 7576-16-1 2022 View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active (4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;N,N-diethylethanamine 926-346-0 - - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (4R,12aS)-7-Benzyloxy-N-[(2,4-difluorophenyl)methyl]-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide 809-887-6 1206102-11-5 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide 809-888-1 1051375-16-6 - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (4R,4aS,7aR,12bS)-3-(ethoxycarbonyl)-7-oxo-1,2,3,4,7,7a-hexahydro-4aH-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diyl diacetate 955-282-6 2387639-94-1 - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (4R,4aS,7aR,12bS)-3-methyl-7-oxo-2,3,4,4a,7,7a-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diyl diacetate 875-213-2 50798-31-7 - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (4R,4aS,7aR,12bS)-4a,9-dihydroxy-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one hemi((2R,3R)-2,3-dihydroxysuccinate) 956-466-9 - - View substance registered dossier
[Confidential] - - - (4R,6R)-4-Hydroxy-2,2,6-trimethylcyclohexanone / 60046-50-6 700-052-0 60046-50-6 - View substance registered dossier
DUKE CHEM, S.A. Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain Spain Active (4R,6S)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol 604-572-8 147128-77-6 - View substance registered dossier
LusoChimica S.p.A. Via Giotto, 9 23871 Lomagna (Lecco) Italy Italy Active (4S)-1-[(2S)-3-(benzoylthio)-2-methyl-1-oxopropyl]-4-(phenylthio)-L-proline potassium salt 617-274-8 81938-42-3 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active (4S)-2-(4-bromophenyl)-4-isopropyl-3-pentanoyl-1,3-oxazolidin-5-one 700-586-4 852212-81-8 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone 848-798-7 272778-12-8 2020 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active (4S)-3-carbamoyl-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridin-1-ium (2S,3S)-2,3-bis(benzoyloxy)-3-carboxypropanoate 947-346-7 - 2020; 2021; 2023 View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (4S)-4-(2-Chlorophenyl)-2-hydroxy-5,5-dimethyl-1,3,2-dioxaphosphinane 2-oxide 623-314-5 98674-86-3 - View substance registered dossier
MOEHS BCN, S.L. C/ Zenc, 12 08755 Castellbisbal Barcelona Spain Spain Active (4S)-4-(3,4-dichlorophenyl)-N-methyl-tetralin-1-imine 811-284-8 312620-93-2 - View substance registered dossier
Phardiag Ltd 70 Sir John Rogersons Quay 4 Dublin Ireland Ireland Active (4S)-4-(phenylsulfanyl)-L-proline 617-252-8 81653-77-2 2009; 2011; 2012 View substance registered dossier
LusoChimica S.p.A. Via Giotto, 9 23871 Lomagna (Lecco) Italy Italy Active (4S)-4-(phenylsulfanyl)-L-proline 617-252-8 81653-77-2 2021 View substance registered dossier
Giusto Faravelli via medardo rosso , 8 20159 milano italy Italy Italy Active (4S)-4-(phenylsulfanyl)-L-proline 617-252-8 81653-77-2 - View substance registered dossier
FERRANIA CHEMICALS S.R.L. Viale della Libertà, 57 17014 Cairo Montenotte (SV) Italy Italy Active (4S)-4-(phenylsulfanyl)-L-proline 617-252-8 81653-77-2 - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active (4S)-4-amino-5-benzyloxy-5-oxo-pentanoic acid 692-605-7 13030-09-6 - View substance registered dossier
Amino Chemicals Ltd Industrial Estate, A61 MRS3000 Marsa Malta Malta Active (4S)-4-cyclohexyl-L-proline 600-406-3 103201-78-1 - View substance registered dossier
Fine and Performance Chemicals Ltd Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom United Kingdom No longer Valid (4S)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4,4a,7a-tetrahydrothieno[3,2-e]thiazine-6-sulfonamide 807-123-6 154127-42-1 2021 View substance registered dossier
ChemLeader 11 Fine & Performance Chemicals Ltd Długosza 67 43-188 Orzesze Poland Poland Active (4S)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4,4a,7a-tetrahydrothieno[3,2-e]thiazine-6-sulfonamide 807-123-6 154127-42-1 - View substance registered dossier
ICROM S.r.l Via delle arti, 33 20863 Concorezzo Italy Italy Active (4S)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4,4a,7a-tetrahydrothieno[3,2-e]thiazine-6-sulfonamide 807-123-6 154127-42-1 - View substance registered dossier
CHEMO BIOSYNTHESIS SRL VIALE ISONZO, 8 20135 MILANO Italy Italy Active (4S,4aR,5aR,6R,6aR,6bS,7S,9aS,11aS,11bR)-6-hydroxy-9a,11b-dimethyl-9-oxohexadeca hydrocyclopenta[1,2]phenanthro[8a,9-b]oxirene-4,7-diyl bis(2,2-dimethylpropanoate) 825-705-8 1235460-56-6 - View substance registered dossier
Hovione FarmaCiencia SA Sete Casas 2674-506 Loures Portugal Portugal Active (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12aoctahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1) 940-053-5 - 2017 View substance registered dossier
Hovione Limited Loughbeg not available Ringaskiddy County Cork Ireland Ireland Active (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12aoctahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1) 940-053-5 - 2017 View substance registered dossier
Cipan - Companhia Industrial Produtora de Antibióticos Rua da Estação, 42 Vala do Carregado 2600-726 Castanheira do Ribatejo Lisboa Portugal Portugal Active (4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide 617-177-0 808-26-4 - View substance registered dossier
Hovione FarmaCiencia SA Sete Casas 2674-506 Loures Portugal Portugal Active (4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide 617-177-0 808-26-4 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide 617-177-0 808-26-4 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-7-[[methoxy(methyl)amino]methyl]-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide 811-441-0 1035654-66-0 - View substance registered dossier
[Confidential] - - - (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide dihydrochloride 611-780-2 59046-78-5 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide; 4-chlorobenzene-1-sulfonic acid 618-775-4 916439-93-5 - View substance registered dossier
Cipan - Companhia Industrial Produtora de Antibióticos Rua da Estação, 42 Vala do Carregado 2600-726 Castanheira do Ribatejo Lisboa Portugal Portugal Active (4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide p-toluenesulfonate 947-931-7 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (4S,4aS,5aR,12aS)-9-amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride (1:1) 604-710-7 149934-21-4 2013; 2018; 2019 View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (4S,4aS,5aR,12aS)-9-amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride (1:1) 604-710-7 149934-21-4 - View substance registered dossier
Cipan - Companhia Industrial Produtora de Antibióticos Rua da Estação, 42 Vala do Carregado 2600-726 Castanheira do Ribatejo Lisboa Portugal Portugal Active (4S,4aS,5aS,6S,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide di(4-chlorobenzenesulfonic acid) 925-915-0 - - View substance registered dossier
DUKE CHEM, S.A. Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain Spain Active (4S,6S)-4H-Thieno[2,3-b]thiopyran-2-sulfonyl chloride, 4-(acetylethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, 824-717-0 403848-30-6 - View substance registered dossier
DUKE CHEM, S.A. Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain Spain Active (4S,6S)-5,6-dihydro-4-[ethylamin-N-(2-nitrobenzenesulfonic)]-6-methyl-4H-thieno(2,3-b)thiopyran-7,7-dioxide 947-800-4 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (4S-trans)-N-(5,6-diidro-6-metil-7,7-diossido-4Htieno[2,3-b]tiopiran-4-il)-acetammide 604-558-1 147086-83-7 - View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active (4Z)-3-ammoniomethyl-4-(methoxyimino)pyrrolidinium dimethanesulfonate 608-799-3 329181-36-4 - View substance registered dossier
Novartis Ringaskiddy Limited . . Ringaskiddy County Cork Ireland Ireland Cease Manufacture (5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid 700-141-4 117570-53-3 2015 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (5-Bromo-2-chloro-phenyl)-(4-ethoxy-phenyl)-methanone 630-623-9 461432-22-4 - View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active (5-Bromo-2-chloro-phenyl)-(4-ethoxy-phenyl)-methanone 630-623-9 461432-22-4 2021 View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Active (5-Bromo-2-chloro-phenyl)-(4-ethoxy-phenyl)-methanone 630-623-9 461432-22-4 2018 View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active (5-bromo-2-chloro-pyrimidin-4-yl)-cyclopentylamine 800-067-3 733039-20-8 - View substance registered dossier
ERREGIERRE SPA Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy Italy Active (5-bromothiophen-2-yl)-phenylmethanone 608-584-4 31161-46-3 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (5-chloro-2-methoxyphenyl)boronic acid 923-256-3 - - View substance registered dossier
FERRANIA CHEMICALS S.R.L. Viale della Libertà, 57 17014 Cairo Montenotte (SV) Italy Italy Active (5-ethyl-2-trimethylsilyloxypyrimidin-4-yl)oxy-trimethylsilane 608-586-5 31167-05-2 2019 View substance registered dossier
EUROAPI Hungary Ltd. Tó utca 1-5. 1045 Budapest Hungary Hungary Active (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-{[2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylate 604-437-3 144690-92-6 - View substance registered dossier
[Confidential] - - - (5E)-9-(dichloromethylidene)-N-hydroxy-2,3,4,6,7,8-hexahydro-1,4-methanonaphthalen-5(1H)-imine 700-700-2 - - View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa-Attiki Greece Greece Active (5E)-9-(dichloromethylidene)-N-hydroxy-2,3,4,6,7,8-hexahydro-1,4-methanonaphthalen-5(1H)-imine 700-700-2 - 2014; 2018; 2020; 2022 View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (5E,9E,13E)-6,10,14,18-tetramethylnonadeca-5,9,13,17-tetraen-2-one 614-276-0 6809-52-5 2018 View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active (5R)-3-(3,4-difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)furan-2-one 957-069-3 2875066-35-4 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (5R,6S)-allyl 6-((R)-1-(tert-butyldimethylsilyloxy)ethyl)-7-oxo-3-(propylthio)-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate 820-260-6 93603-76-0 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (5R,8R,9R,10S,13S,14S)-13-methyl-1,2,4,5,6,7,8,9,10,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthrene-3,17-dione 881-231-1 5696-51-5 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (5S)-1,2,3,4-tetra-O-acetyl-5-[4-chloro-3-(4-ethoxybenzyl)phenyl]-beta-L-xylopyranose 815-962-4 1384242-56-1 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (5S)-1,2,3,4-tetra-O-acetyl-5-[4-chloro-3-(4-ethoxybenzyl)phenyl]-beta-L-xylopyranose 815-962-4 1384242-56-1 - View substance registered dossier
[Confidential] - - - (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-ol 879-204-4 1373116-05-2 - View substance registered dossier
[Confidential] - - - (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate 880-367-9 1289023-67-1 - View substance registered dossier
[Confidential] - - - (5S,6S,9R)-6-(2,3-difluorophenyl)-9-((triisopropylsilyl)oxy)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-aminedihydrochloride 874-683-6 1373116-04-1 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany No longer Valid (5Z)-5-(2-methylpropylidene)imidazolidine-2,4-dione 700-726-4 - 2017 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (5Z)-5-(2-methylpropylidene)imidazolidine-2,4-dione 700-726-4 - 2022 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany No longer Valid (5Z)-5-benzylideneimidazolidine-2,4-dione 700-728-5 74805-60-0 2013 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (5Z)-5-benzylideneimidazolidine-2,4-dione 700-728-5 74805-60-0 2022 View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (5Z)-6,10-dimethylundeca-5,9-dien-2-one 626-253-2 3879-26-3 - View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (5´R,8´S,10´R,13´S,14´S)-13´-methyl-1´,2´,6´,7´8´,12´,13´,14´,15´,16´-decahydro-17´H-spiro[1,3-dioxolane-2,3´-[5,10]epoxycyclopenta[a]phenantren]-17´-one 821-898-8 39931-87-8 2020 View substance registered dossier
[Confidential] - - - (5α)-4,5-epoxy-14-hydroxy-3-methoxymorphinan-6-one 260-887-7 57664-96-7 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active (5α)-4,5-epoxy-17-methyl-6-oxomorphinan-3,14-diyl diacetate 264-989-2 64643-76-1 - View substance registered dossier
Aesica Pharmaceuticals Limited Windmill Industrial Estate Shotton Lane NE23 3JL Cramlington Northumberland United Kingdom United Kingdom No longer Valid (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 2021 View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 - View substance registered dossier
Macfarlan Smith Limited Wheatfield Road EH11 2QA Edinburgh United Kingdom United Kingdom No longer Valid (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 2021 View substance registered dossier
[Confidential] - - - (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 2022 View substance registered dossier
Alkaloida Chemical Company Zrt. Kabay Janos 29 H-4440 Tiszavasvari Hungary Hungary Active (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 - View substance registered dossier
[Confidential] - - - (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride 257-924-4 52446-24-9 - View substance registered dossier
Alcaliber S.A. Ventalomar 1 45007 Toledo Toledo Spain Spain Active (5α)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol 207-385-6 467-04-9 - View substance registered dossier
HH Compliance The Rubicon Centre CIT Campus , Bishopstown T12 Y275 Cork Co Cork Ireland Ireland Active (5α)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol 207-385-6 467-04-9 - View substance registered dossier
HH Compliance Ltd Rubicon Building, CIT Campus Bishopstown None Cork Ireland Ireland Active (5α)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol 207-385-6 467-04-9 2022 View substance registered dossier
Macfarlan Smith Limited Wheatfield Road EH11 2QA Edinburgh United Kingdom United Kingdom No longer Valid (5α)-7,8-didehydro-4,5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one 208-085-8 508-54-3 2021 View substance registered dossier
Macfarlan Smith Limited Wheatfield Road EH11 2QA Edinburgh United Kingdom United Kingdom No longer Valid (5α)-7,8-didehydro-4,5-epoxy-3,14-dihydroxymorphinan-6-one 282-186-5 84116-46-1 2021 View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (5α,6α)-17-(cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol hydrochloride 245-549-9 23277-43-2 - View substance registered dossier
Eli Lilly Kinsale Limited Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland Ireland Active (6-amino-2-pyridyl)-(1-methyl-4-piperidyl)methanone;dihydrate;dihydrochloride 842-055-0 2356133-42-9 - View substance registered dossier
[Confidential] - - - (6-hydroxynaphthalen-2-yl)boronic acid 687-349-8 173194-95-1 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active (6-morpholin-4-ylpyrimidin-4-yl)hydrazine 691-196-2 5767-36-2 - View substance registered dossier
Glaxo Operations UK Glaxo Wellcome House Berkeley Avenue UB6 0NN Greenford Middlesex United Kingdom United Kingdom No longer Valid (6a,8xi,11b,14xi,16a)-6,9-difluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4- dien-21-yl benzoate 938-716-9 - 2021 View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active (6ALPHA,11BETA,16ALPHA,17ALPHA)-6,9-DIFLUORO-11-HYDRO XY-16-METHYL-3-OXO-17- (1-OXOPROPOXY)ANDROSTA-1,4-DIENE-CARBOTHIOIC ACID 617-084-5 80474-45-9 - View substance registered dossier
EUROAPI Germany GmbH Brüningstraße 50 65926 Frankfurt am Main Germany Germany Active (6R)-6-(dimethylamino)-4,4-diphenylheptan-3-one 603-081-6 125-58-6 2022 View substance registered dossier
EUROAPI Germany GmbH Brüningstraße 50 65926 Frankfurt am Main Germany Germany Active (6R)-6-Dimethylamino-4,4-diphenyl-heptan-3-one; compound with 2-(toluene-4-sulfonylamino)-pentanedioic acid 921-925-4 - 2022 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (6R*,7R*)-7-hydroxy-6-[(propan-2-yl)amino]-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one 862-404-0 119520-05-7 - View substance registered dossier
Corden Pharma Latina S.p.A. Via Murillo, 7 IT04013 Sermoneta (LT) Lazio Italy Italy Cease Manufacture (6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3) 939-998-6 - 2017 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3) 939-998-6 - - View substance registered dossier
Corden Pharma Latina S.p.A. Via Murillo, 7 IT04013 Sermoneta (LT) Lazio Italy Italy Active (6R,7R)-3-chloromethyl-7-{(Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)2-[(1-carboxy-1-methylethoxy)imino]acetylamino}-8-oxo-5-thia-1-azbicyclo[4.2.0]oct-2-ene-2-carboxylic acid p-methoxybenzyl ester 939-996-5 689294-28-8 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R,7R)-3-chloromethyl-7-{(Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)2-[(1-carboxy-1-methylethoxy)imino]acetylamino}-8-oxo-5-thia-1-azbicyclo[4.2.0]oct-2-ene-2-carboxylic acid p-methoxybenzyl ester 939-996-5 689294-28-8 2014 View substance registered dossier
FRESENIUS KABI iPSUM s.r.l. Via Roma, 108 20060 Cassina de' Pecchi (MI) Italy Italy Active (6R,7R)-7-[[(2Z)-(2-Aminothiazol-4-yl)(methoxy-imino)acetyl]amino]-3-[1-methylpyrrolidinio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate dihydrochloride 827-945-9 107648-80-6 - View substance registered dossier
FRESENIUS KABI iPSUM s.r.l. Via Roma, 108 20060 Cassina de' Pecchi (MI) Italy Italy Active (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[2-methyl-1-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 600-349-4 102772-66-7 - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[2-methyl-1-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 600-349-4 102772-66-7 2021 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[2-methyl-1-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 600-349-4 102772-66-7 - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrochloride 600-507-2 103980-44-5 2021 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-7-amino-3-(5H-imidazo[1,2-b]pyridazin-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydroiodide 606-382-0 197897-11-3 2021 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-7-amino-3-{[(furan-2-ylcarbonyl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 617-065-1 80370-59-8 2021 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (6R,7R)-7-Amino-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4,2,0]oct-2-ene-2-carboxylic acid 438-350-5 79349-82-9 2012; 2017 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 700-301-3 69739-16-8 2021 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R,7R)-benzhydryl 3-hydroxy-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 611-177-4 54639-48-4 2013 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-benzhydryl 3-hydroxy-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 611-177-4 54639-48-4 2021 View substance registered dossier
Teva Czech Industries s.r.o. Ostravska 29/305 74770 Opava - Komarov Czech Republic Czech Republic Active (6R,7R,14S)-17-cyano-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethano-17-normorphine 921-415-1 - - View substance registered dossier
Teva Czech Industries s.r.o. Ostravska 29/305 74770 Opava - Komarov Czech Republic Czech Republic Active (6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethanomorphine 918-453-6 - - View substance registered dossier
Teva Czech Industries s.r.o. Ostravska 29/305 74770 Opava - Komarov Czech Republic Czech Republic Active (6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-6-O-methyl-6,14-ethano-17-normorphine 917-585-1 - - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R,7S)-Benzhydryl 7-amino-7-methoxy-3-((1-methyl-1H-tetrazol-5-ylthio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 611-404-7 56610-72-1 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R-trans)-7-amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 239-787-2 15690-38-7 - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R-trans)-7-amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 239-787-2 15690-38-7 2021 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R-trans)-7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 250-099-1 30246-33-4 2019 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R-trans)-7-amino-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 619-847-8 111298-82-9 2021 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R-trans)-7-amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 258-907-4 53994-69-7 2019 View substance registered dossier
Centrient Pharmaceuticals Netherlands B.V. Alexander Fleminglaan 1 2613 AX Delft Netherlands Netherlands Active (6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 244-870-1 22252-43-3 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 244-870-1 22252-43-3 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 261-491-7 58909-56-1 - View substance registered dossier
AbbVie Logistics B.V. Zuiderzeelaan 53 8017 JV Zwolle Netherlands Netherlands Active (6S)-1'-tert-butyl-3-chlorospiro[5,7-dihydrocyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-2'-one 881-148-0 1455358-14-1 2022 View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (6S)-2,6-dimethyloct-2-ene-8,8-diyl diacetate 949-377-1 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide 431-140-4 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (6S,12aR)-3,10-Dibromo-12,12a-dihydro-6-phenyl-6H-indolo[1,2-c][1,3]benzoxazine 813-155-1 1585969-16-9 - View substance registered dossier
EUROAPI FRANCE 15 rue Traversière 75012 Paris France France Active (6S,8S,9S,10R,11S,13S,14S,17R)-17-acetyl-11,17-dihydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one 615-123-0 7055-53-0 2021; 2022 View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active (6S,9R,10S,11S,13S,14S,16R,17R)-17-(((diethylamino)(ethyl)-λ4-sulfaneyl)carbonyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[α]phenanthren-17-yl propionate 884-371-1 577970-31-1 - View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active (6S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(propionyloxy)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid 813-979-1 65429-42-7 - View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active (6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid 434-320-0 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (6Z)-6-(hydroxyimino)-5,6-dihydroimidazo[4,5,1-jk][1]benzazepine-2,7(1H,4H)-dione 695-945-4 - - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (7-Bromobenzofuran-5-yl)methanol 876-095-5 286836-24-6 - View substance registered dossier
LABORATORIOS SERVIER S.L. RIO JARAMA 59 45007 TOLEDO Spain Spain Active (7-methoxynaphthalen-1-yl)acetonitrile 461-670-1 - 2011; 2018 View substance registered dossier
EUROAPI Hungary Ltd. Tó utca 1-5. 1045 Budapest Hungary Hungary Active (7-methoxynaphthalen-1-yl)acetonitrile 461-670-1 - 2021 View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active (7-Phenylsulfonyl-6-nitro-chinazolin-4-yl)-(3-chlor-4-fluor-phenyl)-amin 620-069-6 945553-94-6 - View substance registered dossier
CARBOGEN AMCIS B.V. Nieuweweg 2a 3901 BE Veenendaal Netherlands Netherlands Active (7-Phenylsulfonyl-6-nitro-chinazolin-4-yl)-(3-chlor-4-fluor-phenyl)-amin 620-069-6 945553-94-6 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (7-Phenylsulfonyl-6-nitro-chinazolin-4-yl)-(3-chlor-4-fluor-phenyl)-amin 620-069-6 945553-94-6 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate 642-947-8 415927-29-6 - View substance registered dossier
Minakem High Potent s.a. Rue Fonds Jean Pâques 8 1435 Mont-Saint-Guibert Belgium Belgium Active (7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate and (7S,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6, 7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate 943-624-7 - - View substance registered dossier
STERLING CHEMICAL MALTA LTD. HF51, Hal-Far Industrial Estate BBG 3000 Birżebbuġa Malta Malta Active (7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate and (7S,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6, 7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate 943-624-7 - - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate and (7S,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6, 7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate 943-624-7 - 2018 View substance registered dossier
AstraZeneca Alderley Park AZ SHE Chemical Registration SK10 4TF Macclesfield Cheshire United Kingdom United Kingdom No longer Valid (7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate and (7S,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6, 7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate 943-624-7 - 2021 View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[α]phenanthrene-3,17-diol 642-948-3 153004-31-0 - View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active (7S,8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[α]phenanthren-6-one 837-287-4 1107606-70-1 - View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active (7S,8R,9S,13S,14S,17S)-7-(9-chlorononyl)-3,17-dihydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-6-one 955-019-5 - - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active (7S,9aS)-7-[(benzyloxy)methyl]octahydropyrazino[2,1-c][1,4]oxazine dioxalic acid salt 875-887-8 1268364-46-0 - View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione - 2,3,5,6-tetrachlorobenzene-1,4-diol (1:1) 926-987-6 - 2021 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (8R,9S,10R,13S,14S,17R)-17-ethynyl-10,13-dimethyl-1,2,4,7,8,9,10,11,12,13,14,15,16,17,-tetradecahydrospiro[cyclopenta[a]phenanthrene-3,2´-[1,3]dioxolan]-17-ol 610-527-3 50407-76-6 2020 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (8R,9S,13S,14S)-3-(Benzyloxy)-13-methyl-6,7,8,9,11,12,13,14 ,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,2`-[1,3]dioxolane] 844-245-9 162784-26-1 - View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (8R,9S,13S,14S)-3-benzyloxy)-13-methyl-6,7,8,9,11,12,13,14- octahydrospiro[cyclopenta[a]phenanthrene-17,2`[1,3]dioxolane] 844-243-8 534572-67-3 - View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active (8R,9S,13S,14S,17S)-3,17-bis((2-methoxypropan-2-yl)oxy)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[α]phenanthren-6-one 875-633-6 486999-08-0 - View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active (8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-8,9,11,12,14,15,16,17-octahydro-7H-cyclopenta[a]phenanthren-6-one 641-994-1 571-92-6 - View substance registered dossier
[Confidential] - - - (8S,10S,13S,14S,17R)-17-hydroxy-10,13-dimethyl-1,2,4,7,8,10,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolane]-17-carbonitrile 601-332-4 114882-16-5 - View substance registered dossier
CHEMO BIOSYNTHESIS SRL VIALE ISONZO, 8 20135 MILANO Italy Italy Active (8S,13S,14S,17R)-17-allyl-13-methyl-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-17ol 849-739-8 141299-95-8 - View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active (8S,13S,14S,17R)-17-allyl-13-methyl-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-17ol 849-739-8 141299-95-8 - View substance registered dossier
CHEMO BIOSYNTHESIS SRL VIALE ISONZO, 8 20135 MILANO Italy Italy Active (8S,13S,14S,17R)-17-allyl-17-hydroxy-13-methyl-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one 849-749-2 23760-34-1 - View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active (8S,13S,14S,17R)-17-allyl-17-hydroxy-13-methyl-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one 849-749-2 23760-34-1 - View substance registered dossier
EUROAPI FRANCE 15 rue Traversière 75012 Paris France France Active (8S,13S,14S,17S)-17-hydroxy-13-methyl-2,6,7,8,14,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-3-one 600-229-1 10161-33-8 2022 View substance registered dossier
Aceto France SAS 3 Rue de Genève CS 50363 BP 50367 Lyon Cedex 06 France France Active (8~{S},13~{S},14~{S})-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione 610-717-6 5173-46-6 2019 View substance registered dossier
SAFIC ALCAN 13 Cours Valmy 92977 Paris La Défense France France Active (8~{S},13~{S},14~{S})-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione 610-717-6 5173-46-6 - View substance registered dossier
EUROAPI FRANCE 15 rue Traversière 75012 Paris France France Active (9beta,11beta)-3,20-dioxo-9,11-epoxypregna-1,4,16-trien-21-yl acetate 600-439-3 103466-44-0 2021; 2022 View substance registered dossier
Farmabios Spa Via Pavia, 1 27027 Gropello Cairoli PV Italy Italy Active (9beta,11beta)-3,20-dioxo-9,11-epoxypregna-1,4,16-trien-21-yl acetate 600-439-3 103466-44-0 2017 View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active (9H-fluoren-9-yl)methyl (2,5-dioxopyrrolidin-1-yl) carbonate 433-520-5 82911-69-1 - View substance registered dossier
REACH24H CONSULTING GROUP Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active (9H-fluoren-9-yl)methyl (2,5-dioxopyrrolidin-1-yl) carbonate 433-520-5 82911-69-1 - View substance registered dossier
Roche Pharma AG (1) Emil-Barell-Strasse 1 79639 Grenzach-Wyhlen Germany Germany Active (9H-fluoren-9-yl)methyl (2,5-dioxopyrrolidin-1-yl) carbonate 433-520-5 82911-69-1 2010; 2013; 2020; 2022 View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active (9H-fluoren-9-yl)methyl (2,5-dioxopyrrolidin-1-yl) carbonate 433-520-5 82911-69-1 - View substance registered dossier
Chemical and Biopharmaceutical Laboratories of Patras S.A. Industrial area of Patras, Building block 1 25018 Patras Greece Greece Active (9H-fluoren-9-yl)methyl (2,5-dioxopyrrolidin-1-yl) carbonate 433-520-5 82911-69-1 - View substance registered dossier
ABBOTT HEALTHCARE PRODUCTS B.V. C.J. VAN HOUTENLAAN 36 1381CP WEESP Netherlands Netherlands Active (9R,10S,13S)-10,13-dimethyl-17-(2-methyl-1,3-dioxolan-2-yl)spiro[1,2,4,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,2'-1,3-dioxolane] 611-207-6 5488-51-7 2018 View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l. Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy Italy Active (9β,11β,16α)-9,11-epoxy-21-hydroxy-16, 17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione 609-736-2 39672-75-8 - View substance registered dossier
JSC "Olainfarm" Rupnicu str. 5 LV-2114 Olaine Latvia Latvia Active (alpha-cyanobenzyl)malonic acid diethyl ester 922-463-6 - - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (alphaS)-methyl alpha-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetate 2-propyl sulfate 614-478-9 684269-94-1 2021 View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture (Bromomethyl)cyclobutane 700-027-4 17247-58-4 2015 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Cease Manufacture (Bromomethyl)cyclobutane 700-027-4 17247-58-4 2018 View substance registered dossier
EUROAPI Hungary Ltd. Tó utca 1-5. 1045 Budapest Hungary Hungary Active (Bromomethylphenyl-4')-2 benzonitrile 601-327-7 114772-54-2 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active (chloromethyl)cyclopropane 227-632-1 5911-08-0 - View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active (Chloromethyl)dimethoxymethylsilane 606-938-2 2212-11-5 2008; 2011; 2022 View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active (Chloromethyl)methoxydimethylsilane 700-268-5 18143-33-4 2008 View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active (Chloromethyl)trimethoxysilane 611-813-0 5926-26-1 2008; 2011 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (cis)-4-[2-[2-((1S,2S,5S)-6,6-dimethylnorpinan-2-yl)ethoxy]ethyl]morpholine 700-519-9 - 2017 View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active (cis)-4-[2-[2-((1S,2S,5S)-6,6-dimethylnorpinan-2-yl)ethoxy]ethyl]morpholine 700-519-9 - - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (cyclopropylmethoxy)acetic acid 853-795-9 246869-08-9 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (Diethoxyphosphoryl)acetate 608-560-3 3095-95-2 2014 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (Diethoxyphosphoryl)acetate 608-560-3 3095-95-2 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (diethylamino)acetonitrile 221-130-6 3010-02-4 2018 View substance registered dossier
[Confidential] - - - (dimethoxy(methyl)silyl)methanamine 812-377-6 343926-26-1 - View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active (dimethoxy(methyl)silyl)methanamine 812-377-6 343926-26-1 2018 View substance registered dossier
[Confidential] - - - (E)- 1-(4-Methylsubstitutedphenyl-3-(3,5-dimethylaryl)propenone - - - View substance registered dossier
ZaCh System ZI La Croix Cadeaux 49242 Avrillè France France Active (E)-(4-methoxy-2,3,6-trimethylphenyl)-3-buten-2-one 263-760-4 62924-31-6 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (E)-(4-methoxy-2,3,6-trimethylphenyl)-3-buten-2-one 263-760-4 62924-31-6 2018 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active (E)-(5,6-dihydro-1,4,2-dioxazin-3-yl)(2-hydroxyphenyl)methanone O-methyloxime 456-110-8 - 2017; 2022 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active (E)-(5,6-dihydro-1,4,2-dioxazin-3-yl)(2-hydroxyphenyl)methanone O-methyloxime 456-110-8 - 2011; 2014; 2015 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (E)-(6,10-dimethylundeca-1,5,9-trien-2-yl)cyclopropane 834-085-8 714230-50-9 - View substance registered dossier
Blue Cube Germany Assets GmbH & Co. KG Buetzflether Sand 2 21683 Stade Germany Germany Active (E)-1,3-dichloropropene 431-460-4 10061-02-6 2011; 2012; 2021 View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Cease Manufacture (E)-1,3-dichloropropene 431-460-4 10061-02-6 2021 View substance registered dossier
Cosma S.p.A. Via Colleoni 15/17 24040 Ciserano (BG) Italy Italy Active (E)-1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]pyrimidine citrate (1:1) 227-154-3 5685-86-9 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Cease Manufacture (E)-1,4-dibromobut-2-ene 212-472-7 821-06-7 2016 View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Cease Manufacture (E)-1,4-dibromobut-2-ene 212-472-7 821-06-7 2017 View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Cease Manufacture (E)-1,4-dibromobut-2-ene 212-472-7 821-06-7 2015 View substance registered dossier
Contract Chemicals Ltd Penrhyn Road Knowsley Business Park L34 9HY Prescot Merseyside United Kingdom United Kingdom No longer Valid (E)-1,4-dibromobut-2-ene 212-472-7 821-06-7 2021 View substance registered dossier
[Confidential] - - - (E)-1-(4-methylthiophenyl)-3-(3,5-dimethyl-4-tertbutyloxycarbonyldimethylmethylhydroxyphenyl)prop-2-en-1-one - - - View substance registered dossier
[Confidential] - - - (E)-1-methoxyprop-1-ene 615-927-1 7319-16-6 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active (E)-1-propene-1,2,3-tricarboxylic acid 223-688-6 4023-65-8 - View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia Croatia Active (E)-2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-ylmethylene)-5,6-dimethoxy-indan-1-one hydrochloride 940-983-1 - - View substance registered dossier
Fermion Oy Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland Finland Active (E)-2-(2-(4-dibenzo[b,f][1,4]thiazepin-11-yl)piperazin- 1-yl)ethoxy)ethanol hydrochloride 696-107-0 930086-71-8 - View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active (E)-2-chloro-N-[4-chloro-2-[(hydroxyimino)phenylmethyl]phenyl]acetamide 220-755-1 2888-63-3 2017 View substance registered dossier
[Confidential] - - - (E)-2-Ethoxy-N-(2-methyl-1-phenylpropylidene)ethylamine 604-106-3 139007-06-0 - View substance registered dossier
Givaudan Iberica SA Pla d'en Batlle s/n 08470 San Celoni Barcelona Spain Spain Active (E)-2-methyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)but-2-en-1-ol 813-338-6 106155-02-6 2017 View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active (E)-2-methyl-4-phenylpent-2-enal 618-755-5 91495-55-5 - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active (E)-2-methylpent-2-enenitrile 250-694-6 31551-28-7 - View substance registered dossier
Givaudan Iberica SA Pla d'en Batlle s/n 08470 San Celoni Barcelona Spain Spain Active (E)-3,5-dimethylhex-3-en-2-one 606-014-9 18402-86-3 - View substance registered dossier
DSM Nutritional Products GmbH - OR1 Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany Germany Active (E)-3,7,11-trimethyldodeca-1,6,10-trien-3-ol 255-053-4 40716-66-3 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (E)-3,7-dimethylocta-2,6-dienal 205-476-5 141-27-5 2013; 2015; 2016 View substance registered dossier
Givaudan Iberica SA Pla d'en Batlle s/n 08470 San Celoni Barcelona Spain Spain Active (E)-3-(4-isobutylphenyl)-2-methylacrylaldehyde 824-059-4 2147744-66-7 2021 View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom No longer Valid (E)-3-[6-(p-toluoyl)-2-pyridyl]acrylic acid 302-128-5 94094-27-6 2021 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (E)-3-formylbut-2-enyl acetate 247-825-4 26586-02-7 2010; 2013; 2016 View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (E)-3-Methyl-4-oxo-but-2-enoic acid ethylester 690-663-8 62054-49-3 2022 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (E)-3-Methyl-4-oxo-but-2-enoic acid ethylester 690-663-8 62054-49-3 - View substance registered dossier
DSM Nutritional Products France SAS 1 boulevard d'Alsace F-68128 Village-Neuf France France Active (E)-3-methylpent-2-en-4-yn-1-ol 228-169-8 6153-06-6 2015; 2020 View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (E)-3-phenylprop-2-enal 604-377-8 14371-10-9 - View substance registered dossier
Thermofisher Scientific Cork Ltd. Currabinny P43 AY66 Carrigaline Co. Cork Ireland Ireland Active (E)-3-phenylprop-2-enal 604-377-8 14371-10-9 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (E)-4-Dimethylamino-but-2-enoic acid [4-(3-chloro-4-fluoro-phenyl-amino)-7-((S)-(tetrahydrofuran-3-yl)oxy)-quinazoline-6-yl]-amide 923-981-5 - 2015; 2023 View substance registered dossier
Solvay Fluor GmbH Hans-Boeckler-Allee 20 30173 HANNOVER Germany Germany Active (E)-4-Ethoxy-1,1,1-trifluoro-3-buten-2-one (stabilized with BHT) 475-900-3 - 2010; 2014; 2019 View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (E)-5-(3-bromophenyl)pent-4-enoic acid 881-198-3 1180670-58-9 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Cease Manufacture (E)-5-benzyl-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-N-nitro-1,3,5-triazinan-2-imine 606-753-7 213967-55-6 2023 View substance registered dossier
All'Chem rue Marceau 03108 MONTLUCON CEDEX France France Active (E)-5[(4-chlorophenyl)methylene]-2,2-dimethylcyclopentanone 410-440-9 164058-20-2 - View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Cease Manufacture (E)-5[(4-chlorophenyl)methylene]-2,2-dimethylcyclopentanone 410-440-9 164058-20-2 2016 View substance registered dossier
BASF Agri Production SAS 21 Rue de la Sauvegarde 69130 Ecully Rhone France France Active (E)-5[(4-chlorophenyl)methylene]-2,2-dimethylcyclopentanone 410-440-9 164058-20-2 2011 View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (E)-6,10-dimethylundeca-5,9-dien-2-one 223-269-8 3796-70-1 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active (E)-ethyl 4-(dimethylamino)but-2-enoate maleate 941-772-7 - 2015 View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (E)-ethyl N-4-nitrophenoxyacetimidate 617-436-8 83077-00-3 2021 View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active (E)-heptan-2-one oxime 610-969-7 5314-31-8 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Cease Manufacture (E)-methyl 2-acetyloct-2-enoate 807-427-9 228114-02-1 2019 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active (E)-N'-(2-cyano-4-(3-(1-hydroxy-2-methylpropan-2-yl)thioureido)phenyl)-N,N-dimethylformimidamide 814-560-6 1429755-57-6 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active (E)-N'-hydroxy-N-(4-hydroxypyrid-2-yl)formimidamide 952-647-1 - - View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active (E)-N-((dialkylamino)alkylene)-3,5-bis(polyfluoroalkyl)benzamide - - 2016 View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (E)-non-3-en-2-one 813-141-5 18402-83-0 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (E,E)-2,6-bis[1-((2-terbutylphenyl)imino)ethyl]pyridine 881-335-7 253797-84-1 - View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active (E,E)-2,6-bis[1-((2-terbutylphenyl)imino)ethyl]pyridine 881-335-7 253797-84-1 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active (E,E)-3,7,11,15-tetramethylhexadeca-1,6,10,14-tetraen-3-ol 214-201-8 1113-21-9 - View substance registered dossier
Kuraray Europe GmbH Philipp-Reis-Str. 4 65795 Hattersheim Germany Germany Active (E,E)-3,7,11,15-tetramethylhexadeca-1,6,10,14-tetraen-3-ol 214-201-8 1113-21-9 - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (E,E)-3,7,11,15-tetramethylhexadeca-1,6,10,14-tetraen-3-ol 214-201-8 1113-21-9 2018 View substance registered dossier
Zach System ZI La Croix Cadeau 49242 Avrillé France France Active (E,E)-[5-(4-methoxy-2,3,6-trimethylphenyl)-3-methyl-2,4-pentadienyl]triphenylphosphonium chloride 273-975-5 69365-97-5 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (E,E)-[5-(4-methoxy-2,3,6-trimethylphenyl)-3-methyl-2,4-pentadienyl]triphenylphosphonium chloride 273-975-5 69365-97-5 - View substance registered dossier
Chematek s.p.a. Piazzale Libia, 1 20135 Milano Lombardia Italy Italy Active (E,E)-hexa-2,4-dien-1-ol 241-173-4 17102-64-6 - View substance registered dossier
[Confidential] - - - (E,E,E)-2,7-dimethylocta-2,4,6-trienedial 225-756-0 5056-17-7 - View substance registered dossier
Luxcontrol S.A. (OR66) 1, Avenue des Terres Rouges 4331 Esch/Alzette Luxembourg Luxembourg Active (epoxyethyl)benzene 202-476-7 96-09-3 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (epoxyethyl)benzene 202-476-7 96-09-3 2012; 2017 View substance registered dossier
Výzkumný ústav organických syntéz a.s. č.p. 296 533 54 Rybitví Czech Republic Czech Republic Active (epoxyethyl)benzene 202-476-7 96-09-3 - View substance registered dossier
KLK Kolb Specialties B.V. Langestraat 167 7491AE Delden Overijssel Netherlands Netherlands Active (hydroxymethyl)phosphonic acid 220-047-2 2617-47-2 - View substance registered dossier
Sachem Europe BV Van Voordenpark 15 5301 KP Zaltbommel Gelderland Netherlands Netherlands Active (isobutoxymethyl)oxirane 223-303-1 3814-55-9 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (isopropyl (1s,3s)-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclobutane-1-carboxylate) 950-860-4 - 2020 View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active (isopropyl (1s,3s)-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclobutane-1-carboxylate) 950-860-4 - - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Cease Manufacture (methoxymethyl)triphenylphosphonium chloride 223-664-5 4009-98-7 2022 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active (methoxymethyl)triphenylphosphonium chloride 223-664-5 4009-98-7 2019 View substance registered dossier
CARBOGEN AMCIS B.V. Nieuweweg 2a 3901 BE Veenendaal Netherlands Netherlands Active (methoxymethyl)triphenylphosphonium chloride 223-664-5 4009-98-7 - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active (N,N-diethylaniline)trihydroboron 236-305-2 13289-97-9 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (N-(2-methyl-1-phenyl-2 propanyl) acetamide 611-254-2 5531-33-9 2016; 2018 View substance registered dossier
Alzchem Trostberg GmbH Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany Germany Active (N-phenylcarbamimidoyl)ammonium carbonate hydrate 485-350-6 - 2009; 2019 View substance registered dossier
[Confidential] - - - (N-phenylcarbamimidoyl)ammonium carbonate hydrate 485-350-6 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (n-{(1s,3s)-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide hydrochloride) 952-248-2 - 2020 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.