Registered substances

Registered substances

Registered substances

Please note:

As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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(+)-2-amino-1-butanol
227-475-9 5856-62-2 Cease Manufacture Intermediate Joint Cease manufacture 10-04-2017 View substance registered dossier
(+-)-2,4-dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
607-685-0 252964-68-4 Cease Manufacture Full Joint Cease manufacture 29-05-2018 View substance registered dossier
(+/-) tetrahydrofurfuryl (R)-2-[4-(6-chloroquinoxalin-2-yloxy)phenyloxy]propionate
PANTERA; QUIZALOFOP-P-TEFURYL
414-200-4 200509-41-7 Cease Manufacture NONS Joint Cease manufacture 15-12-2008 View substance registered dossier
(+/-)-[(R*,R*)and(R*,S*)]-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran
T001446
419-600-2 99199-90-3 Cease Manufacture NONS Individual Cease manufacture 12-09-2012 View substance registered dossier
(1-chlorocyclohexyl) cyclohexyl ketone
280-893-3 83803-75-2 Cease Manufacture Intermediate Joint Cease manufacture 08-06-2016 View substance registered dossier
(1-methylethylidene)di-4,1-phenylenetetraphenyl diphosphate
425-220-8 5945-33-5 Cease Manufacture Full Individual Cease manufacture 20-11-2012 View substance registered dossier
(10aS)-methyl 10a-methoxy-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate
607-239-5 23495-64-9 Cease Manufacture Full Joint Cease manufacture 28-05-2018 View substance registered dossier
(17α)-17-hydroxy-3-oxoandrost-4-ene-17-carbonitrile
278-780-9 77881-13-1 Cease Manufacture Intermediate Joint Cease manufacture 22-10-2012 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Cease Manufacture Full Individual Cease manufacture 02-04-2013 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Cease Manufacture Full Individual Cease manufacture 17-08-2012 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Cease Manufacture Full Individual Cease manufacture 21-05-2013 View substance registered dossier
(1R,2S,3S,4R)-3-((2-chloro-5-fluoropyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid
821-184-6 1777721-60-4 Cease Manufacture Full Joint Cease manufacture 28-02-2019 View substance registered dossier
(1R,2S,3S,4R)-3-((5-fluoro-2-(5-fluoro-1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic
821-185-1 1777721-63-7 Cease Manufacture Full Joint Cease manufacture 28-02-2019 View substance registered dossier
(1R,3S,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-3-amine fumarate
943-085-8 - Cease Manufacture Intermediate Individual Cease manufacture 04-04-2016 View substance registered dossier
(1S)-1-cyclopropylethanamine; (2R)-2-hydroxy-2-phenyl-acetic acid
946-290-0 2246580-61-8 Cease Manufacture Intermediate Joint Cease manufacture 01-10-2020 View substance registered dossier
(1S,3R,4R,5R)-methyl 3-acetoxy-4,5-dihydroxycyclohexanecarboxylate
839-204-7 1104200-21-6 Cease Manufacture Intermediate Individual Cease manufacture 03-06-2019 View substance registered dossier
(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol hydrochloride
700-391-4 6953-28-2 Cease Manufacture Intermediate Individual Cease manufacture 02-12-2010 View substance registered dossier
(2-hydroxyethyl)(3-hydroxypropyl)dimethylammonium chloride
278-860-3 78182-00-0 Cease Manufacture Intermediate Individual Cease manufacture 30-08-2011 View substance registered dossier
(2R)-2-(2,4-difluorophenyl)-1,1-difluoro-1-{5-[4-(2,2,2-trifluoroethoxy)phenyl]pyridin-2-yl}-3-(1H-tetrazol-1-yl)propan-2-ol
841-499-2 1340593-59-0 Cease Manufacture Full Joint Cease manufacture 25-08-2020 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 82717-96-2 Cease Manufacture Intermediate Individual Cease manufacture 22-11-2011 View substance registered dossier
(2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride (1:1)
695-797-0 93601-86-6 Cease Manufacture Full Joint Cease manufacture 04-07-2018 View substance registered dossier
(2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-aminium (2R)-(2-chlorophenyl)(hydroxy)acetate
814-350-4 1352917-66-8 Cease Manufacture Full Joint Cease manufacture 04-07-2018 View substance registered dossier
(2S,3R,4R,5S,6R)-3,4,5-tris(benzyloxy)-2-methyl-6-(p-tolylthio)tetrahydro-2H-pyran
835-228-7 211801-54-6 Cease Manufacture Intermediate Individual Cease manufacture 05-03-2019 View substance registered dossier
(2α,4aα,8β)-hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalen-8(5H)-one
249-648-8 29461-13-0 Cease Manufacture Full Joint Cease manufacture 24-12-2019 View substance registered dossier
(3 β, 5 α, 6β)-3-(acetyloxy)-5-bromo-6-hydroxy-androstan-17-one
17-KETOBROMOHYDRINE
419-790-7 4229-69-0 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(3-aminophenyl)pyridin-3-ylmethanone
428-230-0 79568-06-2 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(3-aminophenyl)uronium chloride
261-858-1 59690-88-9 Cease Manufacture Full Joint Cease manufacture 29-04-2013 View substance registered dossier
(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl methanesulfonate
700-367-3 35130-97-3 Cease Manufacture Intermediate Individual Cease manufacture 09-02-2010 View substance registered dossier
(3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl[(methylsulfonyl)oxy]acetate
700-396-1 60924-38-1 Cease Manufacture Intermediate Individual Cease manufacture 09-02-2010 View substance registered dossier
(3beta)-17-(3-pyridinyl)androsta-5,16-dien-3-yl acetate compound with (2R,3R)-tartaric acid and methanol (1 : 1 : 1.5)
931-336-4 - Cease Manufacture Intermediate Individual Cease manufacture 13-09-2012 View substance registered dossier
(3S,4aS,8aS)-2-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-tert-butyldecahydroisoquinoline-3-carboxamide
PTH-AA
430-230-0 136522-17-3 Cease Manufacture NONS Individual Cease manufacture 13-09-2010 View substance registered dossier
(3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide
420-380-5 136465-81-1 Cease Manufacture Intermediate Individual Cease manufacture 29-10-2012 View substance registered dossier
(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione
224-832-0 4511-42-6 Cease Manufacture Full Individual Cease manufacture 17-08-2015 View substance registered dossier
(4-benzylpiperazin-1-yl)(cyclopropyl)methanone hydrochloride
816-907-7 1294454-93-5 Cease Manufacture Intermediate Joint Cease manufacture 28-05-2020 View substance registered dossier
(4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid
826-639-2 1817776-86-5 Cease Manufacture Intermediate Joint Cease manufacture 20-07-2020 View substance registered dossier
(4aR*,8aR*)-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one
428-690-2 1668-86-6 Cease Manufacture NONS Individual Cease manufacture 23-11-2010 View substance registered dossier
(4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one
433-160-9 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid
HYDROXYECTOIN
442-870-8 165542-15-4 Cease Manufacture NONS Joint Cease manufacture 10-11-2008 View substance registered dossier
(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid
700-141-4 117570-53-3 Cease Manufacture Intermediate Individual Cease manufacture 22-06-2010 View substance registered dossier
(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)
939-998-6 - Cease Manufacture Intermediate Joint Cease manufacture 24-11-2014 View substance registered dossier
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrochloride
600-507-2 103980-44-5 Cease Manufacture Intermediate Joint Cease manufacture 03-04-2018 View substance registered dossier
(6R,7R)-7-amino-3-(5H-imidazo[1,2-b]pyridazin-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydroiodide
606-382-0 197897-11-3 Cease Manufacture Intermediate Individual Cease manufacture 20-04-2018 View substance registered dossier
(6R,7R)-7-amino-3-{[(furan-2-ylcarbonyl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
617-065-1 80370-59-8 Cease Manufacture Intermediate Joint Cease manufacture 03-04-2018 View substance registered dossier
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
700-301-3 69739-16-8 Cease Manufacture Intermediate Individual Cease manufacture 04-06-2009 View substance registered dossier
(6R-trans)-1-((7-ammonio-2-carboxylato-8-oxo-5-thia-1-azabicyclo-[4.2.0]oct-2-en-3-yl)methyl)pyridinium iodide
423-260-0 100988-63-4 Cease Manufacture NONS Individual Cease manufacture 29-10-2012 View substance registered dossier
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
261-491-7 58909-56-1 Cease Manufacture Full Joint Cease manufacture 03-05-2018 View substance registered dossier
(8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,8,9,10,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
608-630-3 31528-46-8 Cease Manufacture Full Joint Cease manufacture 10-01-2019 View substance registered dossier
(Bromomethyl)cyclobutane
700-027-4 17247-58-4 Cease Manufacture Intermediate Individual Cease manufacture 31-08-2011 View substance registered dossier
(Bromomethyl)cyclobutane
700-027-4 17247-58-4 Cease Manufacture Intermediate Joint Cease manufacture 14-12-2011 View substance registered dossier
(C12-C14)tert-alkylammonium methylphosphonate
CD 23-404
404-750-3 119415-07-5 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(chloromethyl)bis(4-fluorophenyl)methylsilane
H6572
401-200-4 85491-26-5 Cease Manufacture Full Joint Cease manufacture 29-10-2012 View substance registered dossier
(E)-1,4-dibromobut-2-ene
212-472-7 821-06-7 Cease Manufacture Intermediate Joint Cease manufacture 18-05-2018 View substance registered dossier
(E)-3-(2-chlorophenyl)-2-(4-fluorophenyl)propenal
DPP
410-980-5 112704-51-5 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(E,Z)-2,6-dimethylocta-2,4,6-triene
230-603-6 7216-56-0 Cease Manufacture Full Joint Cease manufacture 17-04-2018 View substance registered dossier
(R)-1-chloro-2,3-epoxypropane
(R)-EPICHLOROHYDRIN
424-280-2 51594-55-9 Cease Manufacture Intermediate Joint Cease manufacture 20-03-2018 View substance registered dossier
(R)-2-(2,4-Difluorphenyl)-1,1-difluor-3-(tetrazol-1-yl)-1-{5-[4-(2,2,2-trifluorethoxy)-phenyl]-2-pyridyl}-2-propanol-(R,R)-tartrate
845-262-4 1809816-36-1 Cease Manufacture Full Joint Cease manufacture 30-09-2020 View substance registered dossier
(R)-3-chloropropane-1,2-diol
435-560-9 57090-45-6 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(S)-1,1-diphenyl-1,2-propanediol
443-220-6 46755-94-6 Cease Manufacture NONS Individual Cease manufacture 26-01-2012 View substance registered dossier
(S)-2-(1-aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one hydrochloride
942-180-1 - Cease Manufacture Intermediate Individual Cease manufacture 28-08-2015 View substance registered dossier
(S)-2-amino-3-(3,4-dimethoxyphenyl)-2-methylpropiononitrile monohydrochloride
219-823-3 2544-13-0 Cease Manufacture Intermediate Joint Cease manufacture 03-12-2013 View substance registered dossier
(S)-3-(tert-butylamino)propane-1,2-diol
250-125-1 30315-46-9 Cease Manufacture Full Joint Cease manufacture 27-08-2020 View substance registered dossier
(S)-3-benzyloxycarbonyl-1,2,3,4-tetrahydro-isoquinolinium 4-methylbenzenesulfonate
BENZYL THIQ TOSYLATE; PD 114683-10; TIC-B
406-960-0 77497-97-3 Cease Manufacture Intermediate Individual Cease manufacture 04-10-2012 View substance registered dossier
(S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle
439-220-0 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(S)-azetidine-2-carboxylic acid 4-cyanobenzylamide hydrochloride
433-010-2 2135910-74-4 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(S)-methyl 5-(4-(benzyloxy)phenyl)-3,4-dihydro-2H-pyrrole-2-carboxylate
815-198-1 934240-38-7 Cease Manufacture Intermediate Joint Cease manufacture 14-03-2018 View substance registered dossier
(S)-tert-butyl(1-((3-fluoro-2-(phenylcarbamoyl)phenyl)amino)-1-oxobutan-2 yl)carbamate
942-159-7 - Cease Manufacture Intermediate Individual Cease manufacture 20-07-2015 View substance registered dossier
(trimethoxysilyl)methyl prop-2-enoate
700-313-9 21134-38-3 Cease Manufacture Intermediate Individual Cease manufacture 18-11-2009 View substance registered dossier
(Z)-4-hydroxy-4-(6-methoxynaphthalen-2-yl)but-3-en-2-one
700-075-6 218768-11-7 Cease Manufacture Intermediate Individual Cease manufacture 11-11-2008 View substance registered dossier
(Z)-Octadec-9-enylamine, ethoxylated
1 - 4.5 moles ethoxylated
500-048-7 26635-93-8 Cease Manufacture Full Joint Cease manufacture 03-10-2018 View substance registered dossier
(±)-2-(6-methoxy-2-naphthyl)propionic acid
247-485-7 26159-31-9 Cease Manufacture Intermediate Joint Cease manufacture 10-09-2013 View substance registered dossier
(η-cumene)-(η-cyclopentadienyl)iron(II) trifluoromethane-sulfonate
CG 26-751
407-880-9 117549-13-0 Cease Manufacture NONS Joint Cease manufacture 26-11-2010 View substance registered dossier
.alpha.-D-Glucopyranose, 1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-, 2,3,4,6-tetraacetate
921-285-6 1071929-02-6 Cease Manufacture Intermediate Individual Cease manufacture 29-09-2015 View substance registered dossier
.beta.-Alanine, N-[2-chloro-4-[2-(4-nitrophenyl)diazenyl]phenyl]-, 2-[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]-2-oxoethyl ester
435-990-7 371921-34-5 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
.beta.-Alanine, N-[3-(acetylamino)-4-[2-(2-cyano-4,6-dinitrophenyl)diazenyl]phenyl]-N-ethyl-, 2-oxo-2-phenylethyl ester
454-440-7 682809-44-5 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
.beta.-Alanine, N-[5-(acetylamino)-4-[2-(2-chloro-4,6-dinitrophenyl)diazenyl]-2-methoxyphenyl]-, 2-oxo-2-(phenylmethoxy)ethyl ester
436-000-6 159010-67-0 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
.beta.-Alanine, N-[[2-(chloromethyl)-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-, ethyl ester
936-788-6 1307233-94-8 Cease Manufacture Intermediate Joint Cease manufacture 05-09-2012 View substance registered dossier
.beta.-Neuraminic acid, N-acetyl-, methyl ester, hydrate (1:1)
700-205-1 50998-13-5 Cease Manufacture Intermediate Individual Cease manufacture 11-01-2010 View substance registered dossier
.beta.-Neuraminic acid, N-acetyl-4-deoxy-4-(di-2-propen-1-ylamino)-, methyl ester, 7,8,9-triacetate
700-779-3 1434079-71-6 Cease Manufacture Intermediate Individual Cease manufacture 31-05-2012 View substance registered dossier
1(2H)-Isoquinolinone, 7-chloro-
813-122-1 24188-74-7 Cease Manufacture Intermediate Individual Cease manufacture 07-09-2016 View substance registered dossier
1(2H)-Isoquinolinone, 7-chloro-4-methoxy-
813-123-7 630423-35-7 Cease Manufacture Intermediate Individual Cease manufacture 07-09-2016 View substance registered dossier
1,1'-(1,3-phenylenedioxy)bis(3-(2-(prop-2-enyl)phenoxy)propan-2-ol)
COMPIMIDE™ 121
405-840-5 110866-35-8 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
1,1'-[methylenebis(oxy)]dibutane
219-909-0 2568-90-3 Cease Manufacture Intermediate Individual Cease manufacture 06-05-2011 View substance registered dossier
1,1,1-tris(phenyl-4'-(6''-diazo-5'',6''-dihydro-5''-oxo-naphthalene-1''-sulfonato)ethane;reaction mass of: 1,1,1-tris(phenyl-4'-(3''-diazo-3'',4''-dihydro-4''-oxo-naphthalene-1''-sulfonato)ethane;reaction product of 1,1,1-tris(p-hydroxyphenyl)ethane with 6-diazo-5,6-dihydro-5-oxo-1-naphthylsulfonylchloride and 3-diazo-3,4-dihydro-4-oxo-1-naphthylsulfonylchloride (1:2);reaction product of 1,1,1-tris(p-hydroxyphenyl)ethane with 6-diazo-5,6-dihydro-5-oxo-1-naphthylsulfonylchloride and 3-diazo-3,4-dihydro-4-oxo-1-naphthylsulfonylchloride (2:1)
422-760-6 - Cease Manufacture NONS Individual Cease manufacture 07-02-2011 View substance registered dossier
1,1,2,2,3,3,4,4,4-nonafluoro-N,N-bis(2-hydroxyethyl)butane-1-sulphonamide
252-044-7 34455-00-0 Cease Manufacture Full Joint Cease manufacture 02-10-2018 View substance registered dossier
1,1,2,2,3,3,4,4,4-nonafluoro-N-methylbutane-1-sulfonamide
614-396-3 68298-12-4 Cease Manufacture Intermediate Individual Cease manufacture 30-03-2021 View substance registered dossier
1,1,2,2-tetramethoxyethane
463-280-7 - Cease Manufacture NONS Individual Cease manufacture 01-03-2018 View substance registered dossier
1,1-dimethylethyl 4'-(bromomethyl)biphenyl-2-carboxylate
442-850-9 114772-40-6 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
1,2,3,4-tetrahydroisoquinoline
202-050-0 91-21-4 Cease Manufacture Intermediate Joint Cease manufacture 21-08-2013 View substance registered dossier
1,2,3-triaqua-1,2:1,2:1,3:1,3:2,3:2,3-hexa-μ-acetato-(O,O')-μ3-oxo-triangulo-triiridium acetate
IR 112
417-670-9 52705-52-9 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
1,2,4-Thiadiazole-3-acetic acid, 5-amino-.alpha.-(methoxyimino)-, (.alpha.Z)-
456-150-6 72217-12-0 Cease Manufacture NONS Individual Cease manufacture 04-03-2011 View substance registered dossier
1,2,4-Thiadiazole-3-ethanethioic acid, 5-amino-.alpha.-[(triphenylmethoxy)imino]-, S-2-benzothiazolyl ester, (.alpha.Z)-
447-420-4 209467-59-4 Cease Manufacture NONS Individual Cease manufacture 22-02-2013 View substance registered dossier
1,2-Benzenediamine, N1-methyl-4-(methylsulfonyl)-
615-907-2 73097-51-5 Cease Manufacture Intermediate Individual Cease manufacture 30-08-2013 View substance registered dossier
1,2-Benzenedicarbonitrile, 3-nitro-
450-650-8 51762-67-5 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
1,2-Benzenedicarboxylic acid, di-C6-10-alkyl esters 271-094-0 68515-51-5 Cease Manufacture Full Joint Cease manufacture 23-03-2016 View substance registered dossier
1,2-bis(vinylsulfonylacetamido)ethane
H-603
404-790-1 66710-66-5 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
1,2-bis[4-fluoro-6-{4-sulfo-5-(2-(4-sulfonaphtalene-3-ylazo)-1-hydroxy-3,6-disulfo-8-aminonaphthalene-7-ylazo)phenylamino}-1,3,5-triazin-2-ylamino]ethane;x-sodium, y-potassium salts x = 7,755 y = 0,245
REACTIVE NAVY DER 7678
417-610-1 155522-09-1 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
1,2-dihydroxyanthraquinone
200-782-5 72-48-0 Cease Manufacture Full Joint Cease manufacture 15-05-2018 View substance registered dossier
1,2-Ethanediamine, N1-(5-methoxy-2-nitrophenyl)-, hydrochloride (1:1)
415-480-0 86419-69-4 Cease Manufacture NONS Joint Cease manufacture 10-11-2008 View substance registered dossier
1,2-Ethanediamine, N1-[(6-chloro-3-pyridinyl)methyl]-
600-261-6 101990-44-7 Cease Manufacture Intermediate Individual Cease manufacture 15-12-2010 View substance registered dossier
1,3,4-Thiadiazole, 2-(methylsulfonyl)-5-(trifluoromethyl)-
809-978-0 27603-25-4 Cease Manufacture Intermediate Joint Cease manufacture 05-05-2015 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Sicor - Società Italiana Corticosteroidi S.r.l. Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy Italy Cease Manufacture (+)-2-amino-1-butanol 227-475-9 5856-62-2 2022 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (+-)-2,4-dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one 607-685-0 252964-68-4 2021 View substance registered dossier
ESIM Chemicals GmbH St.-Peter-Strasse 25 4020 Linz Austria Austria Cease Manufacture (+/-) tetrahydrofurfuryl (R)-2-[4-(6-chloroquinoxalin-2-yloxy)phenyloxy]propionate 414-200-4 200509-41-7 2022 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - No longer Valid (+/-) tetrahydrofurfuryl (R)-2-[4-(6-chloroquinoxalin-2-yloxy)phenyloxy]propionate 414-200-4 200509-41-7 2022 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (+/-)-[(R*,R*)and(R*,S*)]-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran 419-600-2 99199-90-3 2017 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Cease Manufacture (1-chlorocyclohexyl) cyclohexyl ketone 280-893-3 83803-75-2 2022 View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Cease Manufacture (1-methylethylidene)di-4,1-phenylenetetraphenyl diphosphate 425-220-8 5945-33-5 2014 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Cease Manufacture (10aS)-methyl 10a-methoxy-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate 607-239-5 23495-64-9 2022 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Cease Manufacture (17α)-17-hydroxy-3-oxoandrost-4-ene-17-carbonitrile 278-780-9 77881-13-1 2022 View substance registered dossier
ROQUETTE Frères 1 rue de la haute loge 62136 LESTREM Cedex France France Cease Manufacture (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 2018 View substance registered dossier
REACH COMPLIANCE SERVICES LIMITED Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Cease Manufacture (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 2021 View substance registered dossier
REACH24H CONSULTING GROUP Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Cease Manufacture (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 2021 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (1R,2S,3S,4R)-3-((2-chloro-5-fluoropyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid 821-184-6 1777721-60-4 2022 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (1R,2S,3S,4R)-3-((5-fluoro-2-(5-fluoro-1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic 821-185-1 1777721-63-7 2022 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture (1R,3S,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-3-amine fumarate 943-085-8 - 2021 View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Cease Manufacture (1S)-1-cyclopropylethanamine; (2R)-2-hydroxy-2-phenyl-acetic acid 946-290-0 2246580-61-8 2022 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture (1S)-1-cyclopropylethanamine; (2R)-2-hydroxy-2-phenyl-acetic acid 946-290-0 2246580-61-8 2022 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture (1S,3R,4R,5R)-methyl 3-acetoxy-4,5-dihydroxycyclohexanecarboxylate 839-204-7 1104200-21-6 2020 View substance registered dossier
Productos Esteve Internacional, S.A Avd. Verge Montserrat, 12. 08024 Barcelona Barcelona Spain Spain Cease Manufacture (2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol hydrochloride 700-391-4 6953-28-2 2017 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Cease Manufacture (2-hydroxyethyl)(3-hydroxypropyl)dimethylammonium chloride 278-860-3 78182-00-0 2020 View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Cease Manufacture (2R)-2-(2,4-difluorophenyl)-1,1-difluoro-1-{5-[4-(2,2,2-trifluoroethoxy)phenyl]pyridin-2-yl}-3-(1H-tetrazol-1-yl)propan-2-ol 841-499-2 1340593-59-0 2022 View substance registered dossier
TAMARANG, S.A. Balmes, 84, 4-2 08008 Barcelona Barcelona Spain Spain Cease Manufacture (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 82717-96-2 2012 View substance registered dossier
Avara Shannon Pharmaceutical Services Limited Shannon Industrial Estate V14 FX09 Shannon Clare Ireland Ireland Cease Manufacture (2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride (1:1) 695-797-0 93601-86-6 2021 View substance registered dossier
Avara Shannon Pharmaceutical Services Limited Shannon Industrial Estate V14 FX09 Shannon Clare Ireland Ireland Cease Manufacture (2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-aminium (2R)-(2-chlorophenyl)(hydroxy)acetate 814-350-4 1352917-66-8 2021 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture (2S,3R,4R,5S,6R)-3,4,5-tris(benzyloxy)-2-methyl-6-(p-tolylthio)tetrahydro-2H-pyran 835-228-7 211801-54-6 2021 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Cease Manufacture (2α,4aα,8β)-hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalen-8(5H)-one 249-648-8 29461-13-0 2020 View substance registered dossier
Aspen Oss BV Kloosterstraat 6 5349 AB Oss Netherlands Netherlands Cease Manufacture (3 β, 5 α, 6β)-3-(acetyloxy)-5-bromo-6-hydroxy-androstan-17-one 419-790-7 4229-69-0 2019 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture (3-aminophenyl)pyridin-3-ylmethanone 428-230-0 79568-06-2 2015 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Cease Manufacture (3-aminophenyl)uronium chloride 261-858-1 59690-88-9 2022 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl methanesulfonate 700-367-3 35130-97-3 2012 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl[(methylsulfonyl)oxy]acetate 700-396-1 60924-38-1 2012 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (3beta)-17-(3-pyridinyl)androsta-5,16-dien-3-yl acetate compound with (2R,3R)-tartaric acid and methanol (1 : 1 : 1.5) 931-336-4 - 2019 View substance registered dossier
Roche Ireland Limited Clarehill . Clarecastle Ireland Ireland Cease Manufacture (3S,4aS,8aS)-2-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-tert-butyldecahydroisoquinoline-3-carboxamide 430-230-0 136522-17-3 2020 View substance registered dossier
Roche Ireland Limited Clarehill . Clarecastle Ireland Ireland Cease Manufacture (3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide 420-380-5 136465-81-1 2020 View substance registered dossier
Santrol Europe ApS Aagade 103 Pjedsted 7000 Fredericia Denmark Denmark Cease Manufacture (3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione 224-832-0 4511-42-6 2016 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Cease Manufacture (4-benzylpiperazin-1-yl)(cyclopropyl)methanone hydrochloride 816-907-7 1294454-93-5 2021 View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Cease Manufacture (4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid 826-639-2 1817776-86-5 2022 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture (4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid 826-639-2 1817776-86-5 2022 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (4aR*,8aR*)-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one 428-690-2 1668-86-6 2019 View substance registered dossier
- - - - (4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one 433-160-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - No longer Valid (4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid 442-870-8 165542-15-4 2022 View substance registered dossier
- - - - (4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid 442-870-8 165542-15-4 - View substance registered dossier
Novartis Ringaskiddy Limited . . Ringaskiddy County Cork Ireland Ireland Cease Manufacture (5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid 700-141-4 117570-53-3 2015 View substance registered dossier
Corden Pharma Latina S.p.A. Via Murillo, 7 IT04013 Sermoneta (LT) Lazio Italy Italy Cease Manufacture (6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3) 939-998-6 - 2017 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrochloride 600-507-2 103980-44-5 2021 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-7-amino-3-(5H-imidazo[1,2-b]pyridazin-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydroiodide 606-382-0 197897-11-3 2021 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-7-amino-3-{[(furan-2-ylcarbonyl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 617-065-1 80370-59-8 2021 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 700-301-3 69739-16-8 2021 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R-trans)-1-((7-ammonio-2-carboxylato-8-oxo-5-thia-1-azabicyclo-[4.2.0]oct-2-en-3-yl)methyl)pyridinium iodide 423-260-0 100988-63-4 2021 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 261-491-7 58909-56-1 2020 View substance registered dossier
Aspen Oss BV Kloosterstraat 6 5349 AB Oss Netherlands Netherlands Cease Manufacture (8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,8,9,10,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one 608-630-3 31528-46-8 2022 View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture (Bromomethyl)cyclobutane 700-027-4 17247-58-4 2015 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Cease Manufacture (Bromomethyl)cyclobutane 700-027-4 17247-58-4 2018 View substance registered dossier
BASF Lampertheim GmbH Chemiestrasse 22 68619 Lampertheim Germany Germany Cease Manufacture (C12-C14)tert-alkylammonium methylphosphonate 404-750-3 119415-07-5 2018 View substance registered dossier
[Confidential] - - - (chloromethyl)bis(4-fluorophenyl)methylsilane 401-200-4 85491-26-5 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Cease Manufacture (E)-1,4-dibromobut-2-ene 212-472-7 821-06-7 2016 View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Cease Manufacture (E)-1,4-dibromobut-2-ene 212-472-7 821-06-7 2017 View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Cease Manufacture (E)-1,4-dibromobut-2-ene 212-472-7 821-06-7 2015 View substance registered dossier
Contract Chemicals Ltd Penrhyn Road Knowsley Business Park L34 9HY Prescot Merseyside United Kingdom United Kingdom No longer Valid (E)-1,4-dibromobut-2-ene 212-472-7 821-06-7 2021 View substance registered dossier
BASF Schwarzheide GmbH Schipkauer Str. 1 01987 Schwarzheide Brandenburg Germany Germany Cease Manufacture (E)-3-(2-chlorophenyl)-2-(4-fluorophenyl)propenal 410-980-5 112704-51-5 2018 View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Cease Manufacture (E,Z)-2,6-dimethylocta-2,4,6-triene 230-603-6 7216-56-0 2021 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Cease Manufacture (R)-1-chloro-2,3-epoxypropane 424-280-2 51594-55-9 2022 View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Cease Manufacture (R)-2-(2,4-Difluorphenyl)-1,1-difluor-3-(tetrazol-1-yl)-1-{5-[4-(2,2,2-trifluorethoxy)-phenyl]-2-pyridyl}-2-propanol-(R,R)-tartrate 845-262-4 1809816-36-1 2022 View substance registered dossier
COVANCE CLINICAL DEVELOPMENT SA 171 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Cease Manufacture (R)-3-chloropropane-1,2-diol 435-560-9 57090-45-6 2012 View substance registered dossier
DSM Nutritional Products GmbH Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany Germany Cease Manufacture (S)-1,1-diphenyl-1,2-propanediol 443-220-6 46755-94-6 2019 View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Cease Manufacture (S)-2-(1-aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one hydrochloride 942-180-1 - 2017 View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l. Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy Italy Cease Manufacture (S)-2-amino-3-(3,4-dimethoxyphenyl)-2-methylpropiononitrile monohydrochloride 219-823-3 2544-13-0 2022 View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l. Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy Italy Cease Manufacture (S)-3-(tert-butylamino)propane-1,2-diol 250-125-1 30315-46-9 2022 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Cease Manufacture (S)-3-benzyloxycarbonyl-1,2,3,4-tetrahydro-isoquinolinium 4-methylbenzenesulfonate 406-960-0 77497-97-3 2017 View substance registered dossier
- - - - (S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle 439-220-0 - - View substance registered dossier
AstraZeneca B313:5 AZ GlobalSHE- Chem.Reg. SE-15185 Södertälje Sweden Sweden Cease Manufacture (S)-azetidine-2-carboxylic acid 4-cyanobenzylamide hydrochloride 433-010-2 2135910-74-4 2012 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Cease Manufacture (S)-methyl 5-(4-(benzyloxy)phenyl)-3,4-dihydro-2H-pyrrole-2-carboxylate 815-198-1 934240-38-7 2022 View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Cease Manufacture (S)-tert-butyl(1-((3-fluoro-2-(phenylcarbamoyl)phenyl)amino)-1-oxobutan-2 yl)carbamate 942-159-7 - 2017 View substance registered dossier
Dow Silicones Belgium SPRL OR-1 rue Jules Bordet Parc industriel C 7180 Seneffe Belgium Belgium Cease Manufacture (trimethoxysilyl)methyl prop-2-enoate 700-313-9 21134-38-3 2012 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Cease Manufacture (Z)-4-hydroxy-4-(6-methoxynaphthalen-2-yl)but-3-en-2-one 700-075-6 218768-11-7 2017 View substance registered dossier
Nouryon Surface Chemistry AB Stenunge Allé 3 S-44485 Stenungsund Sweden Sweden Cease Manufacture (Z)-Octadec-9-enylamine, ethoxylated 500-048-7 26635-93-8 2021 View substance registered dossier
NetSun EU B.V. Blaak 40, Fifth Floor 3011 TA Rotterdam Netherlands Netherlands Cease Manufacture (±)-2-(6-methoxy-2-naphthyl)propionic acid 247-485-7 26159-31-9 2019 View substance registered dossier
Stadex Nederland BV Boxbergerweg 119 7431PM Diepenveen Netherlands Netherlands Cease Manufacture (±)-2-(6-methoxy-2-naphthyl)propionic acid 247-485-7 26159-31-9 2013 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - No longer Valid (η-cumene)-(η-cyclopentadienyl)iron(II) trifluoromethane-sulfonate 407-880-9 117549-13-0 2022 View substance registered dossier
Colors & Effects France S.A.S. Rue de la Chapelle 28 68330 Huningue France France Cease Manufacture (η-cumene)-(η-cyclopentadienyl)iron(II) trifluoromethane-sulfonate 407-880-9 117549-13-0 2018 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - No longer Valid (η-cumene)-(η-cyclopentadienyl)iron(II) trifluoromethane-sulfonate 407-880-9 117549-13-0 2022 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - No longer Valid (η-cumene)-(η-cyclopentadienyl)iron(II) trifluoromethane-sulfonate 407-880-9 117549-13-0 2022 View substance registered dossier
Huntsman Advanced Materials (Europe) BV Everslaan 45 B-3078 Everberg Belgium Belgium Cease Manufacture (η-cumene)-(η-cyclopentadienyl)iron(II) trifluoromethane-sulfonate 407-880-9 117549-13-0 2022 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - No longer Valid (η-cumene)-(η-cyclopentadienyl)iron(II) trifluoromethane-sulfonate 407-880-9 117549-13-0 2022 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture .alpha.-D-Glucopyranose, 1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-, 2,3,4,6-tetraacetate 921-285-6 1071929-02-6 2019 View substance registered dossier
Archroma Italy, S.r.l. - OR Via Manzoni 37 20030 Palazzolo Milanese Italy Italy Cease Manufacture .beta.-Alanine, N-[2-chloro-4-[2-(4-nitrophenyl)diazenyl]phenyl]-, 2-[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]-2-oxoethyl ester 435-990-7 371921-34-5 2017 View substance registered dossier
Archroma Italy, S.r.l. - OR Via Manzoni 37 20030 Palazzolo Milanese Italy Italy Cease Manufacture .beta.-Alanine, N-[3-(acetylamino)-4-[2-(2-cyano-4,6-dinitrophenyl)diazenyl]phenyl]-N-ethyl-, 2-oxo-2-phenylethyl ester 454-440-7 682809-44-5 2017 View substance registered dossier
Archroma Italy, S.r.l. - OR Via Manzoni 37 20030 Palazzolo Milanese Italy Italy Cease Manufacture .beta.-Alanine, N-[5-(acetylamino)-4-[2-(2-chloro-4,6-dinitrophenyl)diazenyl]-2-methoxyphenyl]-, 2-oxo-2-(phenylmethoxy)ethyl ester 436-000-6 159010-67-0 2017 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture .beta.-Alanine, N-[[2-(chloromethyl)-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-, ethyl ester 936-788-6 1307233-94-8 2016 View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Cease Manufacture .beta.-Alanine, N-[[2-(chloromethyl)-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-, ethyl ester 936-788-6 1307233-94-8 2016 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture .beta.-Neuraminic acid, N-acetyl-, methyl ester, hydrate (1:1) 700-205-1 50998-13-5 2019 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture .beta.-Neuraminic acid, N-acetyl-4-deoxy-4-(di-2-propen-1-ylamino)-, methyl ester, 7,8,9-triacetate 700-779-3 1434079-71-6 2020 View substance registered dossier
[Confidential] - - - 1(2H)-Isoquinolinone, 7-chloro- 813-122-1 24188-74-7 - View substance registered dossier
[Confidential] - - - 1(2H)-Isoquinolinone, 7-chloro-4-methoxy- 813-123-7 630423-35-7 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Cease Manufacture 1,1'-(1,3-phenylenedioxy)bis(3-(2-(prop-2-enyl)phenoxy)propan-2-ol) 405-840-5 110866-35-8 2018 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Cease Manufacture 1,1'-[methylenebis(oxy)]dibutane 219-909-0 2568-90-3 2020 View substance registered dossier
Merck Performance Materials GmbH Rheingaustrasse 190-196 65203 Wiesbaden Germany Germany Cease Manufacture 1,1,1-tris(phenyl-4'-(6''-diazo-5'',6''-dihydro-5''-oxo-naphthalene-1''-sulfonato)ethane;reaction mass of: 1,1,1-tris(phenyl-4'-(3''-diazo-3'',4''-dihydro-4''-oxo-naphthalene-1''-sulfonato)ethane;reaction product of 1,1,1-tris(p-hydroxyphenyl)ethane with 6-diazo-5,6-dihydro-5-oxo-1-naphthylsulfonylchloride and 3-diazo-3,4-dihydro-4-oxo-1-naphthylsulfonylchloride (1:2);reaction product of 1,1,1-tris(p-hydroxyphenyl)ethane with 6-diazo-5,6-dihydro-5-oxo-1-naphthylsulfonylchloride and 3-diazo-3,4-dihydro-4-oxo-1-naphthylsulfonylchloride (2:1) 422-760-6 - 2019 View substance registered dossier
3M Belgium BVBA/SPRL (OR1) Hermeslaan 7 1831 Diegem Belgium Belgium Cease Manufacture 1,1,2,2,3,3,4,4,4-nonafluoro-N,N-bis(2-hydroxyethyl)butane-1-sulphonamide 252-044-7 34455-00-0 2022 View substance registered dossier
3M Belgium BVBA/SPRL Hermeslaan 7 1831 Diegem Belgium Belgium Cease Manufacture 1,1,2,2,3,3,4,4,4-nonafluoro-N-methylbutane-1-sulfonamide 614-396-3 68298-12-4 2022 View substance registered dossier
WeylChem Lamotte S.A.S Rue du Flottage B.P. 1 60350 Trosly Breuil France France Cease Manufacture 1,1,2,2-tetramethoxyethane 463-280-7 - 2019 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture 1,1-dimethylethyl 4'-(bromomethyl)biphenyl-2-carboxylate 442-850-9 114772-40-6 2015 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Cease Manufacture 1,2,3,4-tetrahydroisoquinoline 202-050-0 91-21-4 2022 View substance registered dossier
- - - - 1,2,3-triaqua-1,2:1,2:1,3:1,3:2,3:2,3-hexa-μ-acetato-(O,O')-μ3-oxo-triangulo-triiridium acetate 417-670-9 52705-52-9 - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture 1,2,4-Thiadiazole-3-acetic acid, 5-amino-.alpha.-(methoxyimino)-, (.alpha.Z)- 456-150-6 72217-12-0 2021 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture 1,2,4-Thiadiazole-3-ethanethioic acid, 5-amino-.alpha.-[(triphenylmethoxy)imino]-, S-2-benzothiazolyl ester, (.alpha.Z)- 447-420-4 209467-59-4 2019 View substance registered dossier
Huntsman Textile Effects (Germany) GmbH Rehlinger Str. 1 D-86462 Langweid a.Lech Germany Germany Cease Manufacture 1,2-Benzenediamine, N1-methyl-4-(methylsulfonyl)- 615-907-2 73097-51-5 2021 View substance registered dossier
Lanxess Deutschland GmbH Kennedyplatz 1 50569 Köln Germany Germany Cease Manufacture 1,2-Benzenedicarbonitrile, 3-nitro- 450-650-8 51762-67-5 2012 View substance registered dossier
Ineos Solvents Germany GmbH Roemerstr. 733 47443 Moers Germany Germany Cease Manufacture 1,2-Benzenedicarboxylic acid, di-C6-10-alkyl esters 271-094-0 68515-51-5 2018 View substance registered dossier
FujiFilm Manufacturing Europe BV Oudenstaart 1 5047 TK Tilburg Netherlands Netherlands Cease Manufacture 1,2-bis(vinylsulfonylacetamido)ethane 404-790-1 66710-66-5 2019 View substance registered dossier
Huntsman Textile Effects (Germany) GmbH Rehlinger Str. 1 D-86462 Langweid a.Lech Germany Germany Cease Manufacture 1,2-bis[4-fluoro-6-{4-sulfo-5-(2-(4-sulfonaphtalene-3-ylazo)-1-hydroxy-3,6-disulfo-8-aminonaphthalene-7-ylazo)phenylamino}-1,3,5-triazin-2-ylamino]ethane;x-sodium, y-potassium salts x = 7,755 y = 0,245 417-610-1 155522-09-1 2014 View substance registered dossier
Vlisco Netherlands BV Binnen Parallelweg 27 5701 PH Helmond NB Netherlands Netherlands Cease Manufacture 1,2-dihydroxyanthraquinone 200-782-5 72-48-0 2021 View substance registered dossier
- - - - 1,2-Ethanediamine, N1-(5-methoxy-2-nitrophenyl)-, hydrochloride (1:1) 415-480-0 86419-69-4 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Cease Manufacture 1,2-Ethanediamine, N1-[(6-chloro-3-pyridinyl)methyl]- 600-261-6 101990-44-7 2022 View substance registered dossier
[Confidential] - - - 1,3,4-Thiadiazole, 2-(methylsulfonyl)-5-(trifluoromethyl)- 809-978-0 27603-25-4 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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