Registered substances

Registered substances

Registered substances

Please note:

As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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(3aα,4β,7β,7aα)-octahydro-4,7-methano-1H-indene
220-585-8 2825-82-3 Active Full Joint ≥ 10 to < 100 tonnes 31-03-2022 View substance registered dossier
(3E)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one 701-394-3 1782069-81-1 No longer Valid Full Joint No longer valid 07-07-2021 View substance registered dossier
(3E)-3-methyl-5-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]pent-3-en-2-one
948-348-0 208034-56-4 Active Intermediate Joint Intermediate use only 10-09-2019 View substance registered dossier
(3E)-dec-3-en-2-one
701-234-2 18402-84-1 Active Full Joint ≥ 100 to < 1 000 tonnes 27-09-2019 View substance registered dossier
(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-ol
810-303-7 459-89-2 Active Intermediate Joint Intermediate use only 25-09-2018 View substance registered dossier
(3H)-benzofuran-2-one
209-052-0 553-86-6 Active Full Joint ≥ 1 to < 10 tonnes 28-10-2020 View substance registered dossier
(3R)-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-amine
836-285-0 125349-37-3 Active Intermediate Joint Intermediate use only 01-08-2022 View substance registered dossier
(3R)-2,3-dihydro-1,1,3-trimethyl-1H-Inden-4-amine-(2S,3S)-2,3-dihydroxybutanedioate
701-382-8 - Active Intermediate Joint Intermediate use only 09-04-2021 View substance registered dossier
(3R)-3,7-dimethyloct-6-enenitrile
- - Active Full Joint ≥ 1 to < 10 tonnes 07-10-2022 View substance registered dossier
(3R)-3-Amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one hydrochloride
813-550-9 486459-71-6 Active Intermediate Joint Intermediate use only 28-02-2022 View substance registered dossier
(3R)-3-methyl-5-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylene-decahydronaphthalen-1-yl]pent-1-en-3-ol
637-366-1 596-85-0 Active Intermediate Joint Intermediate use only 29-05-2018 View substance registered dossier
(3R,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diyl bis(4-hydroxybenzoate)
606-059-4 185756-31-4 Active Intermediate Joint Intermediate use only 13-12-2017 View substance registered dossier
(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-OL
605-076-4 156928-09-5 Active Full Joint ≥ 10 to < 100 tonnes 28-05-2018 View substance registered dossier
(3R,4R,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol
856-563-5 1355049-94-3 Active Intermediate Joint Intermediate use only 24-08-2020 View substance registered dossier
(3R,4R,5R)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one
851-368-1 55094-52-5 Active Intermediate Joint Intermediate use only 10-09-2020 View substance registered dossier
(3R,4R,5R)-3,4-bis(phenylmethoxy)-5-(phenylmethoxymethyl)oxolan-2-ol
857-989-4 16838-89-4 Active Intermediate Joint Intermediate use only 01-09-2020 View substance registered dossier
(3R,4R,5S)-4-amino-5-azido-3-(1-ethyl-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester
805-634-9 204255-04-9 Active Intermediate Joint Intermediate use only 25-05-2018 View substance registered dossier
(3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine-3-carboxylic acid
820-324-3 1428243-24-6 Active Intermediate Joint Intermediate use only 23-03-2018 View substance registered dossier
(3R,4S,5R)-3,4,5-trihydroxycyclohex-1-enecarboxylic acid
205-334-2 138-59-0 Active Intermediate Joint Intermediate use only 01-10-2019 View substance registered dossier
(3R,4S,6R,7R,9R,11S,12R,13S,14R)-6-{[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy]-10-(hydroxyimino)-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one
918-279-0 - Active Intermediate Joint Intermediate use only 26-04-2017 View substance registered dossier
(3R,5R)-tert-Butyl 7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate
603-817-6 134395-00-9 Active Intermediate Joint Intermediate use only 28-09-2017 View substance registered dossier
(3R,5Z)-3-METHYL-5-CYCLOPENTADECEN-1-ONE
851-742-4 464207-51-0 Active Full Joint ≥ 1 to < 10 tonnes 28-05-2020 View substance registered dossier
(3R,6S)-1-benzyl-6-methylpiperidin-3-amine acetyl-L-leucinate [1:1]
840-203-9 2295746-51-7 Active Intermediate Joint Intermediate use only 24-11-2020 View substance registered dossier
(3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate
228-502-7 6283-74-5 Active Intermediate Joint Intermediate use only 21-01-2022 View substance registered dossier
(3RS,3aRS,6SR,7aSR)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone and (3RS,3aSR,6RS,7aRS)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone
429-980-1 - Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
(3S)-3,7-Dimethyl-1-octanol
814-059-2 68680-98-8 Active Full Joint ≥ 1 to < 10 tonnes 30-05-2018 View substance registered dossier
(3S)-3,7-dimethylocta-1,6-dien-1-yl acetate
946-529-9 1439355-19-7 Active Intermediate Joint Intermediate use only 24-01-2018 View substance registered dossier
(3S)-3-thiophen-2-ylsulfanylbutanoic acid
948-811-7 133359-80-5 Active Intermediate Joint Intermediate use only 23-10-2018 View substance registered dossier
(3S)-3-{4-[8-(2,4-dichlorophenyl)-3-(methoxycarbonyl)-6,7-dihydro-5H-benzocyclohepten-9-yl]phenoxy}-1-(3-fluoropropyl)pyrrolidinium hydrogen oxalate
950-060-5 - Active Intermediate Joint Intermediate use only 15-01-2020 View substance registered dossier
(3S,1R)-3-N-Boc-aminocyclopentan-1-ol
807-383-0 167465-99-8 Active Intermediate Joint Intermediate use only 04-05-2018 View substance registered dossier
(3S,3S’)-Dineopentyl 4,4’-disulfanediylbis(3-(benzyloxycarbonylamino)butane-1-sulfonate
954-955-1 - Active Intermediate Joint Intermediate use only 27-09-2021 View substance registered dossier
(3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide
420-380-5 136465-81-1 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-1-benzyl-4-(4-fluorophenyl)piperidine
929-011-7 - Active Intermediate Joint Intermediate use only 20-04-2018 View substance registered dossier
(3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine
924-787-3 110429-36-2 Active Intermediate Joint Intermediate use only 08-03-2021 View substance registered dossier
(3S,4S)-3-hexyl-4-[(R)-2-hydroxytridecyl]-2-oxetanone
THL-HBL
418-650-2 104872-06-2 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate
436-150-2 - Active Intermediate Joint Intermediate use only 16-05-2018 View substance registered dossier
(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate
436-150-2 - Active Intermediate Joint Intermediate use only 12-07-2013 View substance registered dossier
(3S,5S,6S,9R)-6-isopropyl-3,9-dimethyl-1,4- and (3S,5R,6S,9R)-6-isopropyl-3,9-dimethyl-1,4-
457-410-1 831213-72-0 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol
450-320-3 - Active Full Joint ≥ 0 to < 10 tonnes 16-04-2018 View substance registered dossier
(3S,6R,9S,12R,15S,18R,21S,24R)-6,18-dibenzyl-3,9,15,21-tetraisobutyl-4,10,12,16,22,24-hexamethyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclo-tetracosane-2,5,8,11,14,17,20,23-octaone
444-350-6 133413-70-4 Active Intermediate Joint Intermediate use only 24-09-2019 View substance registered dossier
(3S,6S,7R,8R)-8-Benzyl-3-{[(3-hydroxy-4-methoxypyridin-2-yl)carbonyl]amino}-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl 2-methylpropanoate
844-009-5 167173-85-5 Active Intermediate Joint Intermediate use only 04-02-2022 View substance registered dossier
(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione
224-832-0 4511-42-6 Active Full Joint ≥ 1 000 to < 10 000 tonnes 01-08-2022 View substance registered dossier
(3S-trans)-phenyl-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-piperidinecarboxylate
430-510-2 253768-88-6 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(3α,5β,7β)-3,7-Dihydroxy-24-norcholane-23-nitrile
828-107-5 118316-12-4 Active Intermediate Joint Intermediate use only 05-09-2018 View substance registered dossier
(3β)-17-(1,1,1-trifluoromethanesulfonate)-Androsta-5,16-diene-3,17-diol, 3-(2,2,2-trifluoroacetate)
840-627-4 1802323-89-2 Active Intermediate Joint Intermediate use only 26-06-2019 View substance registered dossier
(3β)-3-[(2,2,2-trifluoroacetyl)oxy]-Androst-5-en-17-one
840-626-9 3798-17-2 Active Intermediate Joint Intermediate use only 26-06-2019 View substance registered dossier
(3β,20β)-3-acetoxy-11-oxoolean-12-en-29-oic acid
228-475-1 6277-14-1 Active Full Joint ≥ 0 to < 10 tonnes 27-06-2019 View substance registered dossier
(3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-yl butyrate
250-567-5 31316-20-8 Active Intermediate Joint Intermediate use only 24-01-2022 View substance registered dossier
(4'-methyl-3-fluoro[1,1'-biphenyl]-4-yl)-boronic acid
- - Active Full Joint ≥ 0 to < 10 tonnes 05-07-2022 View substance registered dossier
(4,5-dibromo-1H-pyrrol-2-yl)(phenyl)methanone
700-338-5 50372-61-7 Active Intermediate Joint Intermediate use only 05-10-2016 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (3aα,4β,7β,7aα)-octahydro-4,7-methano-1H-indene 220-585-8 2825-82-3 2021 View substance registered dossier
Diehl Defence Alte Nußdorfer Straße 13 88662 Überlingen Baden Württemberg Germany Germany Active (3aα,4β,7β,7aα)-octahydro-4,7-methano-1H-indene 220-585-8 2825-82-3 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany No longer Valid (3E)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one 701-394-3 1782069-81-1 2021 View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (3E)-3-methyl-5-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]pent-3-en-2-one 948-348-0 208034-56-4 2019 View substance registered dossier
ESIM Chemicals GmbH St.-Peter-Strasse 25 4020 Linz Austria Austria Active (3E)-dec-3-en-2-one 701-234-2 18402-84-1 - View substance registered dossier
Givaudan France Fragrances SA 19-23, Voie des Bans, B.P. 98 95102 Argenteuil France France Active (3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-ol 810-303-7 459-89-2 - View substance registered dossier
Givaudan France SAS - OR1 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France France Active (3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-ol 810-303-7 459-89-2 2018 View substance registered dossier
WeylChem Lamotte S.A.S Rue du Flottage B.P. 1 60350 Trosly Breuil France France Active (3H)-benzofuran-2-one 209-052-0 553-86-6 2019; 2020 View substance registered dossier
Syngenta Ltd Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom United Kingdom No longer Valid (3H)-benzofuran-2-one 209-052-0 553-86-6 2021 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active (3R)-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-amine 836-285-0 125349-37-3 2021; 2022 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active (3R)-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-amine 836-285-0 125349-37-3 - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active (3R)-2,3-dihydro-1,1,3-trimethyl-1H-Inden-4-amine-(2S,3S)-2,3-dihydroxybutanedioate 701-382-8 - - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (3R)-3,7-dimethyloct-6-enenitrile - - 2018; 2022 View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (3R)-3-Amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one hydrochloride 813-550-9 486459-71-6 2022 View substance registered dossier
[Confidential] - - - (3R)-3-methyl-5-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylene-decahydronaphthalen-1-yl]pent-1-en-3-ol 637-366-1 596-85-0 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Cease Manufacture (3R)-3-methyl-5-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylene-decahydronaphthalen-1-yl]pent-1-en-3-ol 637-366-1 596-85-0 2020 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (3R,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diyl bis(4-hydroxybenzoate) 606-059-4 185756-31-4 - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-OL 605-076-4 156928-09-5 - View substance registered dossier
Janssen Pharmaceutical Science Unlimited Company Little Island County NA Cork Ireland Ireland Active (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-OL 605-076-4 156928-09-5 - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Cease Manufacture (3R,4R,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol 856-563-5 1355049-94-3 2021 View substance registered dossier
Gilead Sciences Ireland UC IDA Business &Technology Park Carrigtohill Cork Cork Ireland Ireland Active (3R,4R,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol 856-563-5 1355049-94-3 - View substance registered dossier
Gilead Sciences Ireland UC IDA Business &Technology Park Carrigtohill Cork Cork Ireland Ireland Active (3R,4R,5R)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one 851-368-1 55094-52-5 2020 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (3R,4R,5R)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one 851-368-1 55094-52-5 - View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active (3R,4R,5R)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one 851-368-1 55094-52-5 - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (3R,4R,5R)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one 851-368-1 55094-52-5 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (3R,4R,5R)-3,4-bis(phenylmethoxy)-5-(phenylmethoxymethyl)oxolan-2-ol 857-989-4 16838-89-4 - View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Active (3R,4R,5S)-4-amino-5-azido-3-(1-ethyl-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester 805-634-9 204255-04-9 - View substance registered dossier
[Confidential] - - - (3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine-3-carboxylic acid 820-324-3 1428243-24-6 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture (3R,4S,5R)-3,4,5-trihydroxycyclohex-1-enecarboxylic acid 205-334-2 138-59-0 2020 View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Cease Manufacture (3R,4S,5R)-3,4,5-trihydroxycyclohex-1-enecarboxylic acid 205-334-2 138-59-0 2021 View substance registered dossier
Roche Pharma AG (1) Emil-Barell-Strasse 1 79639 Grenzach-Wyhlen Germany Germany Active (3R,4S,5R)-3,4,5-trihydroxycyclohex-1-enecarboxylic acid 205-334-2 138-59-0 2014; 2019 View substance registered dossier
Ercros SA Avenida Diagonal 593-595 08014 Barcelona Spain Spain Active (3R,4S,6R,7R,9R,11S,12R,13S,14R)-6-{[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy]-10-(hydroxyimino)-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one 918-279-0 - - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (3R,5R)-tert-Butyl 7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate 603-817-6 134395-00-9 - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (3R,5Z)-3-METHYL-5-CYCLOPENTADECEN-1-ONE 851-742-4 464207-51-0 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (3R,6S)-1-benzyl-6-methylpiperidin-3-amine acetyl-L-leucinate [1:1] 840-203-9 2295746-51-7 2020 View substance registered dossier
All'Chem rue Marceau 03108 MONTLUCON CEDEX France France Active (3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate 228-502-7 6283-74-5 2018 View substance registered dossier
EUROAPI FRANCE 15 rue Traversière 75012 Paris France France Active (3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate 228-502-7 6283-74-5 2021; 2022 View substance registered dossier
- - - - (3RS,3aRS,6SR,7aSR)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone and (3RS,3aSR,6RS,7aRS)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone 429-980-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (3RS,3aRS,6SR,7aSR)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone and (3RS,3aSR,6RS,7aRS)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone 429-980-1 - - View substance registered dossier
TAKASAGO TEPL-OR(1) 12 rue Torricelli 75017 Paris France France Active (3S)-3,7-Dimethyl-1-octanol 814-059-2 68680-98-8 - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (3S)-3,7-dimethylocta-1,6-dien-1-yl acetate 946-529-9 1439355-19-7 - View substance registered dossier
DUKE CHEM, S.A. Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain Spain Active (3S)-3-thiophen-2-ylsulfanylbutanoic acid 948-811-7 133359-80-5 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (3S)-3-{4-[8-(2,4-dichlorophenyl)-3-(methoxycarbonyl)-6,7-dihydro-5H-benzocyclohepten-9-yl]phenoxy}-1-(3-fluoropropyl)pyrrolidinium hydrogen oxalate 950-060-5 - - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (3S,1R)-3-N-Boc-aminocyclopentan-1-ol 807-383-0 167465-99-8 - View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active (3S,1R)-3-N-Boc-aminocyclopentan-1-ol 807-383-0 167465-99-8 - View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active (3S,3S’)-Dineopentyl 4,4’-disulfanediylbis(3-(benzyloxycarbonylamino)butane-1-sulfonate 954-955-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active (3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide 420-380-5 136465-81-1 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide 420-380-5 136465-81-1 - View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-1-benzyl-4-(4-fluorophenyl)piperidine 929-011-7 - - View substance registered dossier
Thermofisher Scientific Cork Ltd. Currabinny P43 AY66 Carrigaline Co. Cork Ireland Ireland Active (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine 924-787-3 110429-36-2 2021 View substance registered dossier
CHEMI S.p.A. Via dei lavoratori, 54 20092 Cinisello balsamo Lombardia Italy Italy Active (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine 924-787-3 110429-36-2 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (3S,4S)-3-hexyl-4-[(R)-2-hydroxytridecyl]-2-oxetanone 418-650-2 104872-06-2 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Cease Manufacture (3S,4S)-3-hexyl-4-[(R)-2-hydroxytridecyl]-2-oxetanone 418-650-2 104872-06-2 2022 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Austrian competent national authority. - - No longer Valid (3S,4S)-3-hexyl-4-[(R)-2-hydroxytridecyl]-2-oxetanone 418-650-2 104872-06-2 2022 View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active (3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate 436-150-2 - - View substance registered dossier
MSD International GmbH Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active (3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate 436-150-2 - 2011; 2015 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate 436-150-2 - - View substance registered dossier
[Confidential] - - - (3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate 436-150-2 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (3S,5S,6S,9R)-6-isopropyl-3,9-dimethyl-1,4- and (3S,5R,6S,9R)-6-isopropyl-3,9-dimethyl-1,4- 457-410-1 831213-72-0 - View substance registered dossier
- - - - (3S,5S,6S,9R)-6-isopropyl-3,9-dimethyl-1,4- and (3S,5R,6S,9R)-6-isopropyl-3,9-dimethyl-1,4- 457-410-1 831213-72-0 - View substance registered dossier
TAKASAGO TEPL-OR(1) 12 rue Torricelli 75017 Paris France France Active (3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol 450-320-3 - 2018 View substance registered dossier
Bayer Animal Health GmbH Alfred Nobel Straße 50 40789 Monheim Germany Germany Active (3S,6R,9S,12R,15S,18R,21S,24R)-6,18-dibenzyl-3,9,15,21-tetraisobutyl-4,10,12,16,22,24-hexamethyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclo-tetracosane-2,5,8,11,14,17,20,23-octaone 444-350-6 133413-70-4 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active (3S,6R,9S,12R,15S,18R,21S,24R)-6,18-dibenzyl-3,9,15,21-tetraisobutyl-4,10,12,16,22,24-hexamethyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclo-tetracosane-2,5,8,11,14,17,20,23-octaone 444-350-6 133413-70-4 2010; 2018 View substance registered dossier
Corteva Agriscience Belgium B.V. Rue Montoyer 25, 1000 Brussels Belgium Belgium Active (3S,6S,7R,8R)-8-Benzyl-3-{[(3-hydroxy-4-methoxypyridin-2-yl)carbonyl]amino}-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl 2-methylpropanoate 844-009-5 167173-85-5 - View substance registered dossier
Purac Bioquímica S.A.U. Gran Vial 19-25 08160 Montmeló (Barcelona) Spain Spain Active (3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione 224-832-0 4511-42-6 - View substance registered dossier
Purac Biochem bv Arkelsedijk 46 4206AC Gorinchem Netherlands Netherlands Active (3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione 224-832-0 4511-42-6 2011; 2015; 2022 View substance registered dossier
TotalEnergies Corbion BV Stadhuisplein 70 4203 NS Gorinchem Netherlands Netherlands Active (3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione 224-832-0 4511-42-6 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione 224-832-0 4511-42-6 - View substance registered dossier
Futerro SA Rue du Renouveau 7760 Escannafles Belgium Belgium Active (3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione 224-832-0 4511-42-6 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (3S-trans)-phenyl-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-piperidinecarboxylate 430-510-2 253768-88-6 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (3S-trans)-phenyl-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-piperidinecarboxylate 430-510-2 253768-88-6 - View substance registered dossier
Farmabios Spa Via Pavia, 1 27027 Gropello Cairoli PV Italy Italy Active (3α,5β,7β)-3,7-Dihydroxy-24-norcholane-23-nitrile 828-107-5 118316-12-4 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (3β)-17-(1,1,1-trifluoromethanesulfonate)-Androsta-5,16-diene-3,17-diol, 3-(2,2,2-trifluoroacetate) 840-627-4 1802323-89-2 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (3β)-3-[(2,2,2-trifluoroacetyl)oxy]-Androst-5-en-17-one 840-626-9 3798-17-2 - View substance registered dossier
Indena S.p.A. Viale Ortles, 12 20139 Milan Italy Italy Active (3β,20β)-3-acetoxy-11-oxoolean-12-en-29-oic acid 228-475-1 6277-14-1 2019 View substance registered dossier
DSM Nutritional Products France SAS 1 boulevard d'Alsace F-68128 Village-Neuf France France Active (3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-yl butyrate 250-567-5 31316-20-8 2022 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active (4'-methyl-3-fluoro[1,1'-biphenyl]-4-yl)-boronic acid - - 2022 View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active (4,5-dibromo-1H-pyrrol-2-yl)(phenyl)methanone 700-338-5 50372-61-7 2016 View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active (4,5-dibromo-1H-pyrrol-2-yl)(phenyl)methanone 700-338-5 50372-61-7 2016 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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