Registered substances

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.


 

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
(22S)-22-carboxy-1-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,10,19,24-tetraoxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontan-41-oic acid
815-717-1 1169630-40-3 Active Intermediate Joint Intermediate use only 16-09-2022 View substance registered dossier
(2E)-1,1,1,4,4,4-hexafluoro-2-butene
811-213-0 66711-86-2 Active Full Joint ≥ 10 to < 100 tonnes 23-03-2023 View substance registered dossier
(2E)-2-(4-methylbenzylidene)heptanal
821-749-7 154581-97-2 Active Full Joint ≥ 1 to < 10 tonnes 20-02-2018 View substance registered dossier
(2E)-2-ethyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)but-2-en-1-ol
701-122-3 106185-75-5 Active Full Joint ≥ 1 000 to < 10 000 tonnes 31-05-2022 View substance registered dossier
(2E)-2-methyl-3-(4-methylphenyl)prop-2-en-1-ol
700-548-7 56138-10-4 Active Full Joint ≥ 1 to < 10 tonnes 05-03-2020 View substance registered dossier
(2E)-2-methyl-3-phenylacrylaldehyde
701-219-0 15174-47-7 Active Full Joint ≥ 100 to < 1 000 tonnes 18-06-2021 View substance registered dossier
(2E)-3-(4-AMINO-3,5-DIMETHYLPHENYL)PROP-2-ENENITRILE
610-496-6 500292-86-4 Active Intermediate Joint Intermediate use only 28-05-2018 View substance registered dossier
(2E)-3-(4-methoxyphenyl)-2-methylprop-2-enal
945-034-5 75101-99-4 Active Intermediate Joint Intermediate use only 23-02-2023 View substance registered dossier
(2E)-3-(5,5-dimethyl-1,3-dioxan-2-yl)-2-methylprop-2-enal
610-698-4 51575-61-2 Active Intermediate Joint Intermediate use only 17-07-2015 View substance registered dossier
(2E)-3-[(tert-butoxycarbonyl)(propan-2-yl)amino]-2-(4-chlorophenyl)prop-2-enoic acid
813-178-7 1489004-27-4 Active Intermediate Joint Intermediate use only 24-06-2020 View substance registered dossier
(2E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-2-propenal
425-370-4 93957-50-7 Active Intermediate Joint Intermediate use only 24-09-2010 View substance registered dossier
(2E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-2-propenal
425-370-4 93957-50-7 Active Intermediate Joint Intermediate use only 09-03-2018 View substance registered dossier
(2E)-4,4,4-trifluorobut-2-en-1-ol
835-846-7 83706-94-9 Active Intermediate Joint Intermediate use only 18-07-2019 View substance registered dossier
(2E)-ethyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl) but-2-enal
801-014-7 179107-88-1 Active Intermediate Joint Intermediate use only 10-08-2022 View substance registered dossier
(2E)-N,6,6-trimethyl-N-(1-naphthylmethyl)hept-2-en-4-yn-1-amine
618-706-8 91161-71-6 Active Intermediate Joint Intermediate use only 11-08-2014 View substance registered dossier
(2E)-N,N-diethyl-3,7-dimethyl-octa-2,6-dien-1-amine
814-576-3 40267-53-6 Active Intermediate Joint Intermediate use only 23-10-2020 View substance registered dossier
(2E)-N-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide
811-237-1 698387-09-6 Active Intermediate Joint Intermediate use only 09-11-2015 View substance registered dossier
(2E)-N-(5-Cyano-4-{(E)-[(dimethylamino)methylene]amino}-2-methoxyphenyl)-4-(piperidin-1-yl)but-2-enamide
939-152-6 - Active Intermediate Joint Intermediate use only 27-09-2022 View substance registered dossier
(2E,2'E)-2,4,8,10-tetraoxaspiro[5.5]undecane-3,9-diylbis(2-methylpropane-2,1-diyl) bis(2-cyano-3-(3,4-dimethoxyphenyl)acrylate)
830-560-9 2233585-18-5 Active Full Joint ≥ 1 to < 10 tonnes 24-06-2019 View substance registered dossier
(2E,4E)-2,4-decadienoic acid
250-149-2 30361-33-2 Active Intermediate Joint Intermediate use only 17-04-2020 View substance registered dossier
(2E,4E,7S)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoic acid, ammonium salt (1:1)
619-006-5 942519-41-7 Active Intermediate Joint Intermediate use only 06-04-2018 View substance registered dossier
(2H)chloroform
212-742-4 865-49-6 Active Full Joint ≥ 10 to < 100 tonnes 14-10-2020 View substance registered dossier
(2R)-1-(2,4-difluorophenyl)-2-((tetrahydro-2H-pyran-2-yl)oxy)propan-1-one
823-704-7 126918-17-0 Active Intermediate Joint Intermediate use only 07-04-2018 View substance registered dossier
(2R)-1-morpholino-2-((tetrahydro-2H-pyran-2-yl)oxy)propan-1-one
819-998-1 135270-08-5 Active Intermediate Joint Intermediate use only 19-01-2018 View substance registered dossier
(2R)-1-{5-Amino-2-[1-(benzyloxy)-2-méthyl-2-propanyl]-6-fluoro-1H-indol-1-yl}-3-(benzyloxy)-2-propanol
811-584-9 1294504-67-8 Active Intermediate Joint Intermediate use only 06-07-2022 View substance registered dossier
(2R)-2-(2,4-difluorophenyl)-1,1-difluoro-1-{5-[4-(2,2,2-trifluoroethoxy)phenyl]pyridin-2-yl}-3-(1H-tetrazol-1-yl)propan-2-ol
841-499-2 1340593-59-0 Cease Manufacture Full Joint Cease manufacture 25-08-2020 View substance registered dossier
(2R)-2-(2-chlorophenyl)-2-hydroxyethanoic acid
(R)-2-CHLORO MANDELIC ACID; ACIDE R CHLORO MANDÉLIQUE
444-040-0 52950-18-2 Active Full Joint ≥ 0 to < 10 tonnes 25-09-2013 View substance registered dossier
(2R)-2-(3-Benzoylphenyl)propanoic acid, 1-Deoxy-1-(octylamino)-D-glucitol salt
944-007-5 - Active Intermediate Joint Intermediate use only 13-12-2016 View substance registered dossier
(2R)-2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid
617-435-2 83066-88-0 No longer Valid Intermediate Joint No longer valid 04-11-2020 View substance registered dossier
(2R)-2-amino-2-phenylacetamide
420-370-0 6485-67-2 Active NONS Joint Tonnage data confidential 10-09-2014 View substance registered dossier
(2R)-2-amino-3-(1H-indol-3-yl)propanoic acid hydrochloride
609-287-2 36760-44-8 Active Intermediate Joint Intermediate use only 13-01-2015 View substance registered dossier
(2R)-2-amino-3-phenylpropanoic acid compound with (R)-2-hydroxy-2-phenylacetic acid (1:1)
955-710-1 97251-01-9 Active Intermediate Joint Intermediate use only 01-03-2022 View substance registered dossier
(2R)-2-amino-3-sulfanylpropanoic acid hydrate hydrochloride
615-117-8 7048-04-6 Active Intermediate Joint Intermediate use only 13-03-2018 View substance registered dossier
(2R)-2-aminobutan-1-ol L-tartrate monohydrate
814-787-0 153078-05-8 Active Intermediate Joint Intermediate use only 05-04-2018 View substance registered dossier
(2R)-3-(acetyloxy)-2-[(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methoxy]propyl (2S)-2-amino-3-methylbutanoate hydrochloride
691-736-7 960495-42-5 Active Intermediate Joint Intermediate use only 01-06-2016 View substance registered dossier
(2R)-3-chloropropane-1,2-diol
611-463-9 57090-45-6 Active Intermediate Joint Intermediate use only 07-02-2017 View substance registered dossier
(2R)-3-cyano-2-hydroxy-N,N,N-trimethylpropan-1-aminium chloride
700-669-5 2788-28-5 Active Intermediate Joint Intermediate use only 01-08-2019 View substance registered dossier
(2R)-6-fluoro-2-[(2R)-oxiran-2-yl]-3,4-dihydro-2H-1-benzopyran
606-373-1 197706-50-6 Active Full Joint ≥ 0 to < 10 tonnes 03-06-2019 View substance registered dossier
(2R)-6-fluoro-2-[(2R)-oxiran-2-yl]-3,4-dihydro-2H-1-benzopyran
606-373-1 197706-50-6 Active Intermediate Joint Intermediate use only 18-05-2018 View substance registered dossier
(2R)-6-fluoro-2-[(2S)-oxiran-2-yl]-3,4-dihydro-2H-1-benzopyran
603-315-7 129050-26-6 Active Full Joint ≥ 1 to < 10 tonnes 03-06-2019 View substance registered dossier
(2R)-6-fluoro-2-[(2S)-oxiran-2-yl]-3,4-dihydro-2H-1-benzopyran
603-315-7 129050-26-6 Active Intermediate Joint Intermediate use only 18-05-2018 View substance registered dossier
(2R*)-1-[4-(benzyloxy)phenyl]-1-oxo-N-[(2R*)-1-phenoxypropan-2-yl]propan-2-aminium chloride
867-647-6 1179802-09-5 Active Intermediate Joint Intermediate use only 21-07-2021 View substance registered dossier
(2R,2'R)-3,3'-disulfanediylbis(2-((S)-2-aminopropanamido)propanoic acid)
850-779-3 115888-13-6 Active Full Joint ≥ 1 to < 10 tonnes 23-06-2022 View substance registered dossier
(2R,3R)-2,3-bis(acetyloxy)butanedioic acid - 3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine (1:1)
920-610-9 - Active Intermediate Joint Intermediate use only 25-01-2022 View substance registered dossier
(2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol methanesulfonate
815-196-0 1175536-50-1 Active Intermediate Joint Intermediate use only 31-08-2017 View substance registered dossier
(2R,3R)-3-((R)-1-(tert-butyldimethylsiloxy)ethyl)-4-oxoazetidin-2-yl acetate
4-AA; AOSA; AZETIDONE-KANEKA; GR91990X
408-050-9 76855-69-1 Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
(2R,3R)-3-((R)-1-(tert-butyldimethylsiloxy)ethyl)-4-oxoazetidin-2-yl acetate
4-AA; AOSA; AZETIDONE-KANEKA; GR91990X
408-050-9 76855-69-1 Active Intermediate Joint Intermediate use only 17-01-2023 View substance registered dossier
(2R,3R)-3-(3-(Benzyloxy)phenyl-2-methylpentanoic acid
805-624-4 1367878-84-9 Active Intermediate Joint Intermediate use only 28-05-2020 View substance registered dossier
(2R,3R)-3-(3-Methoxyphenyl)-N,N,2-trimethylpentan-1-amine hydrochloride
837-046-3 175591-17-0 Active Intermediate Joint Intermediate use only 17-08-2022 View substance registered dossier
(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate
479-560-7 989-51-5 Active NONS Joint Tonnage data confidential 12-01-2012 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active (22S)-22-carboxy-1-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,10,19,24-tetraoxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontan-41-oic acid 815-717-1 1169630-40-3 - View substance registered dossier
Novo Nordisk A/S Novo Alle 2880 Bagsværd Denmark Denmark Active (22S)-22-carboxy-1-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,10,19,24-tetraoxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontan-41-oic acid 815-717-1 1169630-40-3 2022 View substance registered dossier
Chemours Netherlands B.V._1 Baanhoekweg 22 3313 LA Dordrecht Netherlands Netherlands Active (2E)-1,1,1,4,4,4-hexafluoro-2-butene 811-213-0 66711-86-2 - View substance registered dossier
Chemours Netherlands B.V. Baanhoekweg 22 3313 LA Dordrecht Netherlands Netherlands Active (2E)-1,1,1,4,4,4-hexafluoro-2-butene 811-213-0 66711-86-2 2016; 2017; 2018; 2019; 2023 View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active (2E)-2-(4-methylbenzylidene)heptanal 821-749-7 154581-97-2 - View substance registered dossier
International Flavors & Fragrances I.F.F. (Nederland) B.V. Liebergerweg 72-98 1221 JT Hilversum Netherlands Netherlands Active (2E)-2-(4-methylbenzylidene)heptanal 821-749-7 154581-97-2 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED(Jiangsu Xinrui Aromatics Ltd) Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (2E)-2-ethyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)but-2-en-1-ol 701-122-3 106185-75-5 - View substance registered dossier
Chemical Inspection & Regulation Service Limited (Hangzhou Grascent Co., Ltd.) Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (2E)-2-ethyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)but-2-en-1-ol 701-122-3 106185-75-5 2019 View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Active (2E)-2-ethyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)but-2-en-1-ol 701-122-3 106185-75-5 2013; 2014; 2015; 2016; 2017; 2022 View substance registered dossier
IFF NL 1 Liebergerweg 72-98 1221 JT Hilversum Netherlands Netherlands Active (2E)-2-ethyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)but-2-en-1-ol 701-122-3 106185-75-5 - View substance registered dossier
FIRMENICH GRASSE SAS OR 4 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (2E)-2-methyl-3-(4-methylphenyl)prop-2-en-1-ol 700-548-7 56138-10-4 2020 View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (2E)-2-methyl-3-(4-methylphenyl)prop-2-en-1-ol 700-548-7 56138-10-4 - View substance registered dossier
International Flavors & Fragrances I.F.F. (Nederland) B.V. Liebergerweg 72-98 1221 JT Hilversum Netherlands Netherlands Active (2E)-2-methyl-3-phenylacrylaldehyde 701-219-0 15174-47-7 - View substance registered dossier
Penman Consulting bvba 10 Avenue des Arts 10 1210 Brussels Belgium Belgium Active (2E)-2-methyl-3-phenylacrylaldehyde 701-219-0 15174-47-7 2012; 2013; 2017; 2018; 2021 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (2E)-3-(4-AMINO-3,5-DIMETHYLPHENYL)PROP-2-ENENITRILE 610-496-6 500292-86-4 - View substance registered dossier
Janssen Pharmaceutical Science Unlimited Company Little Island County NA Cork Ireland Ireland Active (2E)-3-(4-AMINO-3,5-DIMETHYLPHENYL)PROP-2-ENENITRILE 610-496-6 500292-86-4 - View substance registered dossier
Symrise Granada, S.A.U. Crta. Armilla Km 2, 5 18100 Armilla Granada Spain Spain Active (2E)-3-(4-methoxyphenyl)-2-methylprop-2-enal 945-034-5 75101-99-4 - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active (2E)-3-(4-methoxyphenyl)-2-methylprop-2-enal 945-034-5 75101-99-4 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (2E)-3-(4-methoxyphenyl)-2-methylprop-2-enal 945-034-5 75101-99-4 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (2E)-3-(5,5-dimethyl-1,3-dioxan-2-yl)-2-methylprop-2-enal 610-698-4 51575-61-2 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2E)-3-[(tert-butoxycarbonyl)(propan-2-yl)amino]-2-(4-chlorophenyl)prop-2-enoic acid 813-178-7 1489004-27-4 - View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active (2E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-2-propenal 425-370-4 93957-50-7 2010 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (2E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-2-propenal 425-370-4 93957-50-7 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-2-propenal 425-370-4 93957-50-7 - View substance registered dossier
CENTIPHARM Chemin de la Madeleine 06131 GRASSE FRANCE France France Active (2E)-4,4,4-trifluorobut-2-en-1-ol 835-846-7 83706-94-9 - View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Active (2E)-ethyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl) but-2-enal 801-014-7 179107-88-1 2022 View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active (2E)-N,6,6-trimethyl-N-(1-naphthylmethyl)hept-2-en-4-yn-1-amine 618-706-8 91161-71-6 2014 View substance registered dossier
Novartis Ringaskiddy Limited . . Ringaskiddy County Cork Ireland Ireland Active (2E)-N,6,6-trimethyl-N-(1-naphthylmethyl)hept-2-en-4-yn-1-amine 618-706-8 91161-71-6 2014 View substance registered dossier
Novartis Grimsby Limited Moody Lane, Pyewipe DN31 2SR Grimsby N.E. Lincolnshire United Kingdom United Kingdom No longer Valid (2E)-N,6,6-trimethyl-N-(1-naphthylmethyl)hept-2-en-4-yn-1-amine 618-706-8 91161-71-6 2021 View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (2E)-N,N-diethyl-3,7-dimethyl-octa-2,6-dien-1-amine 814-576-3 40267-53-6 2020 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active (2E)-N-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide 811-237-1 698387-09-6 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (2E)-N-(5-Cyano-4-{(E)-[(dimethylamino)methylene]amino}-2-methoxyphenyl)-4-(piperidin-1-yl)but-2-enamide 939-152-6 - - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (2E,2'E)-2,4,8,10-tetraoxaspiro[5.5]undecane-3,9-diylbis(2-methylpropane-2,1-diyl) bis(2-cyano-3-(3,4-dimethoxyphenyl)acrylate) 830-560-9 2233585-18-5 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (2E,4E)-2,4-decadienoic acid 250-149-2 30361-33-2 2020 View substance registered dossier
Výzkumný ústav organických syntéz a.s. č.p. 296 533 54 Rybitví Czech Republic Czech Republic Active (2E,4E,7S)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoic acid, ammonium salt (1:1) 619-006-5 942519-41-7 - View substance registered dossier
Merck Schuchardt OHG Eduard-Buchner-Str. 85662 Hohenbrunn Germany Germany Active (2H)chloroform 212-742-4 865-49-6 - View substance registered dossier
EURISO-TOP Parc des Algorithmes Bât. Homère 91194 SAINT-AUBIN France France Active (2H)chloroform 212-742-4 865-49-6 - View substance registered dossier
Acros Organics bv Janssen Pharmaceuticalaan 3a B-2440 Geel Belgium Belgium Active (2H)chloroform 212-742-4 865-49-6 - View substance registered dossier
Sigma-Aldrich Company Limited The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom United Kingdom No longer Valid (2H)chloroform 212-742-4 865-49-6 2021 View substance registered dossier
SIGMA-ALDRICH CHEMIE GMBH Riedstrasse 2 89555 Steinheim Germany Germany Active (2H)chloroform 212-742-4 865-49-6 2020 View substance registered dossier
knoell Germany - OR - E13 Konrad-Zuse-Ring 25 68163 Mannheim Germany Germany Active (2H)chloroform 212-742-4 865-49-6 - View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active (2R)-1-(2,4-difluorophenyl)-2-((tetrahydro-2H-pyran-2-yl)oxy)propan-1-one 823-704-7 126918-17-0 - View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active (2R)-1-morpholino-2-((tetrahydro-2H-pyran-2-yl)oxy)propan-1-one 819-998-1 135270-08-5 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2R)-1-{5-Amino-2-[1-(benzyloxy)-2-méthyl-2-propanyl]-6-fluoro-1H-indol-1-yl}-3-(benzyloxy)-2-propanol 811-584-9 1294504-67-8 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active (2R)-1-{5-Amino-2-[1-(benzyloxy)-2-méthyl-2-propanyl]-6-fluoro-1H-indol-1-yl}-3-(benzyloxy)-2-propanol 811-584-9 1294504-67-8 - View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Cease Manufacture (2R)-2-(2,4-difluorophenyl)-1,1-difluoro-1-{5-[4-(2,2,2-trifluoroethoxy)phenyl]pyridin-2-yl}-3-(1H-tetrazol-1-yl)propan-2-ol 841-499-2 1340593-59-0 2022 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (2R)-2-(2-chlorophenyl)-2-hydroxyethanoic acid 444-040-0 52950-18-2 2010 View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (2R)-2-(2-chlorophenyl)-2-hydroxyethanoic acid 444-040-0 52950-18-2 2013 View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (2R)-2-(2-chlorophenyl)-2-hydroxyethanoic acid 444-040-0 52950-18-2 2010 View substance registered dossier
Clarochem Ireland Ltd damastown mulhuddart dn 15 dublin Ireland Ireland Active (2R)-2-(3-Benzoylphenyl)propanoic acid, 1-Deoxy-1-(octylamino)-D-glucitol salt 944-007-5 - - View substance registered dossier
Syngenta Ltd Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom United Kingdom No longer Valid (2R)-2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid 617-435-2 83066-88-0 2021 View substance registered dossier
Deretil S.A.U. Villaricos, s/n 04618 Cuevas del Almanzora Almeria Spain Spain Active (2R)-2-amino-2-phenylacetamide 420-370-0 6485-67-2 2011; 2012; 2014 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active (2R)-2-amino-2-phenylacetamide 420-370-0 6485-67-2 - View substance registered dossier
Reuter Chemische Apparatebau e.K. Engesserstrasse 4b 79108 Freiburg Germany Germany Active (2R)-2-amino-3-(1H-indol-3-yl)propanoic acid hydrochloride 609-287-2 36760-44-8 - View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active (2R)-2-amino-3-phenylpropanoic acid compound with (R)-2-hydroxy-2-phenylacetic acid (1:1) 955-710-1 97251-01-9 - View substance registered dossier
ZaCh System ZI La Croix Cadeaux 49242 Avrillè France France Active (2R)-2-amino-3-sulfanylpropanoic acid hydrate hydrochloride 615-117-8 7048-04-6 - View substance registered dossier
Barentz Service S.p.A. via Privata Goito, 8 20037 Paderno Dugnano Italy Italy Active (2R)-2-amino-3-sulfanylpropanoic acid hydrate hydrochloride 615-117-8 7048-04-6 - View substance registered dossier
MOEHS CANTABRA P.I.Requejada Z-23 39313 Polanco Cantabria Spain Spain Active (2R)-2-amino-3-sulfanylpropanoic acid hydrate hydrochloride 615-117-8 7048-04-6 - View substance registered dossier
MOEHS CATALANA Cesar Martinell i Brunet 12 A 08191 Rubi Barcelona Spain Spain Active (2R)-2-amino-3-sulfanylpropanoic acid hydrate hydrochloride 615-117-8 7048-04-6 - View substance registered dossier
MOEHS BCN, S.L. C/ Zenc, 12 08755 Castellbisbal Barcelona Spain Spain Active (2R)-2-amino-3-sulfanylpropanoic acid hydrate hydrochloride 615-117-8 7048-04-6 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2R)-2-amino-3-sulfanylpropanoic acid hydrate hydrochloride 615-117-8 7048-04-6 2013 View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (2R)-2-aminobutan-1-ol L-tartrate monohydrate 814-787-0 153078-05-8 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20090 RODANO Milano Italy Italy No longer Valid (2R)-3-(acetyloxy)-2-[(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methoxy]propyl (2S)-2-amino-3-methylbutanoate hydrochloride 691-736-7 960495-42-5 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (2R)-3-(acetyloxy)-2-[(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methoxy]propyl (2S)-2-amino-3-methylbutanoate hydrochloride 691-736-7 960495-42-5 2012; 2014; 2016 View substance registered dossier
Clarochem Ireland Ltd damastown mulhuddart dn 15 dublin Ireland Ireland Active (2R)-3-chloropropane-1,2-diol 611-463-9 57090-45-6 - View substance registered dossier
Barentz Service S.p.A. via Privata Goito, 8 20037 Paderno Dugnano Italy Italy Active (2R)-3-cyano-2-hydroxy-N,N,N-trimethylpropan-1-aminium chloride 700-669-5 2788-28-5 - View substance registered dossier
Biosint S.p.A. Via Murillo 16 04013 Sermoneta Italy Italy Active (2R)-3-cyano-2-hydroxy-N,N,N-trimethylpropan-1-aminium chloride 700-669-5 2788-28-5 2019 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (2R)-6-fluoro-2-[(2R)-oxiran-2-yl]-3,4-dihydro-2H-1-benzopyran 606-373-1 197706-50-6 2019 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2R)-6-fluoro-2-[(2R)-oxiran-2-yl]-3,4-dihydro-2H-1-benzopyran 606-373-1 197706-50-6 - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (2R)-6-fluoro-2-[(2S)-oxiran-2-yl]-3,4-dihydro-2H-1-benzopyran 603-315-7 129050-26-6 2019 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2R)-6-fluoro-2-[(2S)-oxiran-2-yl]-3,4-dihydro-2H-1-benzopyran 603-315-7 129050-26-6 - View substance registered dossier
Selectchemie Italia Srl Via Messina, 47 20154 Milano Italy Italy Active (2R*)-1-[4-(benzyloxy)phenyl]-1-oxo-N-[(2R*)-1-phenoxypropan-2-yl]propan-2-aminium chloride 867-647-6 1179802-09-5 - View substance registered dossier
ERREGIERRE SPA Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy Italy Active (2R*)-1-[4-(benzyloxy)phenyl]-1-oxo-N-[(2R*)-1-phenoxypropan-2-yl]propan-2-aminium chloride 867-647-6 1179802-09-5 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (2R,2'R)-3,3'-disulfanediylbis(2-((S)-2-aminopropanamido)propanoic acid) 850-779-3 115888-13-6 2022 View substance registered dossier
EUROAPI FRANCE 15 rue Traversière 75012 Paris France France Active (2R,3R)-2,3-bis(acetyloxy)butanedioic acid - 3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine (1:1) 920-610-9 - 2021; 2022 View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active (2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol methanesulfonate 815-196-0 1175536-50-1 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (2R,3R)-3-((R)-1-(tert-butyldimethylsiloxy)ethyl)-4-oxoazetidin-2-yl acetate 408-050-9 76855-69-1 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (2R,3R)-3-((R)-1-(tert-butyldimethylsiloxy)ethyl)-4-oxoazetidin-2-yl acetate 408-050-9 76855-69-1 2023 View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (2R,3R)-3-(3-(Benzyloxy)phenyl-2-methylpentanoic acid 805-624-4 1367878-84-9 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (2R,3R)-3-(3-Methoxyphenyl)-N,N,2-trimethylpentan-1-amine hydrochloride 837-046-3 175591-17-0 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate 479-560-7 989-51-5 - View substance registered dossier
DSM Nutritional Products GmbH Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany Germany Cease Manufacture (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate 479-560-7 989-51-5 2019 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.