Registered substances

Registered substances

Registered substances

Please note:

As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
(S)-(+)-1-methoxy-2-propylamine
700-220-3 99636-32-5 Active Intermediate Individual Intermediate use only 30-09-2010 View substance registered dossier
(S)-(-)-1-(1-Naphthyl)ethylamine (2R,3R)-2,3-dihydroxybutanedioic salt
600-817-8 1073145-07-9 Active Intermediate Joint Intermediate use only 22-01-2018 View substance registered dossier
(S)-(-)-tetrahydro-2-furoic acid
433-770-5 - No longer Valid Intermediate Individual No longer valid 22-09-2011 View substance registered dossier
(S)-(-)-tetrahydro-2-furoic acid
433-770-5 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(S)-(4,5-dihydro-5-thioxo-1,3,4-thiadiazol-2-yl) benzenecarbothioate
257-581-0 51988-14-8 Active Full Joint ≥ 1 to < 10 tonnes 07-11-2022 View substance registered dossier
(S)-1,1-diphenyl-1,2-propanediol
443-220-6 46755-94-6 Cease Manufacture NONS Individual Cease manufacture 26-01-2012 View substance registered dossier
(S)-1,2,4-butanetriyltrimethanesulfonate
UK-164,608
433-850-1 99520-81-7 Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
(S)-1,2-epoxypropane
240-241-0 16088-62-3 Active Intermediate Joint Intermediate use only 16-12-2010 View substance registered dossier
(S)-1-(3-Fluoro-propyl)-3-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenoxy]-pyrrolidine
950-570-8 2114341-28-3 Active Intermediate Joint Intermediate use only 29-07-2022 View substance registered dossier
(S)-1-[2-tert-butoxycarbonyl-3-(2-methoxyethoxy)propyl]-1-cyclopentanecarboxylic acid, cyclohexylamine salt
UK-81,786-57
425-510-4 167944-94-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(S)-1-[3-(acetylthio)-2-methyl-1-oxopropyl]-L-proline
265-250-7 64838-55-7 Active Intermediate Joint Intermediate use only 22-03-2019 View substance registered dossier
(S)-1’- (tert-butyl)-2’-oxo-1’,2’,5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3’-pyrrolo[2,3-b]pyridine]-3-carboxylic acid
- - Active Intermediate Joint Intermediate use only 30-03-2022 View substance registered dossier
(S)-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]-bipyridine]-3-carboxylic acid
- - Active Intermediate Joint Intermediate use only 06-07-2022 View substance registered dossier
(S)-2,2,3-trimethylcyclopent-3-ene-1-acetaldehyde
245-846-3 23727-15-3 Active Intermediate Joint Intermediate use only 07-12-2021 View substance registered dossier
(S)-2,2,4-trimethylpyrrolidine hydrochloride
943-629-4 1897428-40-8 Active Intermediate Joint Intermediate use only 16-07-2018 View substance registered dossier
(S)-2,2-diphenyl-2(3-pyrrolidinyl)acetonitrile hydrobromide
UK-88,861-04
421-810-4 194602-27-2 Active Intermediate Joint Intermediate use only 24-09-2010 View substance registered dossier
(S)-2,3-dihydro-1H-indole-2-carboxylic acid
[S]-2-INDOLINE CARBOXYLIC ACID
410-860-2 79815-20-6 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(S)-2,3-dihydro-1H-indole-2-carboxylic acid
[S]-2-INDOLINE CARBOXYLIC ACID
410-860-2 79815-20-6 Active Intermediate Joint Intermediate use only 17-03-2014 View substance registered dossier
(S)-2,5-Dihydro-pyrrole-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester
873-085-2 74844-93-2 Active Intermediate Joint Intermediate use only 01-06-2022 View substance registered dossier
(S)-2-(1-aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one hydrochloride
942-180-1 - Cease Manufacture Intermediate Individual Cease manufacture 28-08-2015 View substance registered dossier
(S)-2-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid
951-381-3 - Active Intermediate Individual Intermediate use only 02-07-2021 View substance registered dossier
(S)-2-(5-Methylheteromonocycle-2-carboxamido)-alkenoic acid
- - Active Intermediate Joint Intermediate use only 09-10-2013 View substance registered dossier
(S)-2-(5-Oxo-3-propyl-1,2-dihydropyrrol-1-yl) butyramide
824-341-7 357338-13-7 No longer Valid Full Individual No longer valid 02-10-2019 View substance registered dossier
(S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid
FMOC AMINO ACID 4
439-640-4 109425-51-6 Active NONS Joint Tonnage data confidential 17-08-2010 View substance registered dossier
(S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid
FMOC AMINO ACID 4
439-640-4 109425-51-6 Active Intermediate Individual Intermediate use only 07-02-2022 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (S)-(+)-1-methoxy-2-propylamine 700-220-3 99636-32-5 2010 View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (S)-(-)-1-(1-Naphthyl)ethylamine (2R,3R)-2,3-dihydroxybutanedioic salt 600-817-8 1073145-07-9 - View substance registered dossier
Carbogen Amcis Ltd 303 Clayton Lane M11 4SX Manchester Greater Manchester United Kingdom United Kingdom No longer Valid (S)-(-)-tetrahydro-2-furoic acid 433-770-5 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (S)-(-)-tetrahydro-2-furoic acid 433-770-5 - - View substance registered dossier
[Confidential] - - - (S)-(4,5-dihydro-5-thioxo-1,3,4-thiadiazol-2-yl) benzenecarbothioate 257-581-0 51988-14-8 - View substance registered dossier
DSM Nutritional Products GmbH Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany Germany Cease Manufacture (S)-1,1-diphenyl-1,2-propanediol 443-220-6 46755-94-6 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (S)-1,2,4-butanetriyltrimethanesulfonate 433-850-1 99520-81-7 - View substance registered dossier
Labcorp Development SA 169 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active (S)-1,2-epoxypropane 240-241-0 16088-62-3 - View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active (S)-1-(3-Fluoro-propyl)-3-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenoxy]-pyrrolidine 950-570-8 2114341-28-3 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (S)-1-(3-Fluoro-propyl)-3-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenoxy]-pyrrolidine 950-570-8 2114341-28-3 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active (S)-1-[2-tert-butoxycarbonyl-3-(2-methoxyethoxy)propyl]-1-cyclopentanecarboxylic acid, cyclohexylamine salt 425-510-4 167944-94-7 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active (S)-1-[3-(acetylthio)-2-methyl-1-oxopropyl]-L-proline 265-250-7 64838-55-7 2018 View substance registered dossier
FARMHISPANIA S.A. Passeig del Riu Besós, 9-10 08160 Montmeló Barcelona Spain Spain Active (S)-1-[3-(acetylthio)-2-methyl-1-oxopropyl]-L-proline 265-250-7 64838-55-7 2019 View substance registered dossier
L.C.M. TRADING SPA via Mazzini 33 20099 Sesto San Giovanni Lombardia Italy Italy Active (S)-1-[3-(acetylthio)-2-methyl-1-oxopropyl]-L-proline 265-250-7 64838-55-7 - View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active (S)-1’- (tert-butyl)-2’-oxo-1’,2’,5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3’-pyrrolo[2,3-b]pyridine]-3-carboxylic acid - - - View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active (S)-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]-bipyridine]-3-carboxylic acid - - - View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Active (S)-2,2,3-trimethylcyclopent-3-ene-1-acetaldehyde 245-846-3 23727-15-3 2021 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active (S)-2,2,4-trimethylpyrrolidine hydrochloride 943-629-4 1897428-40-8 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (S)-2,2-diphenyl-2(3-pyrrolidinyl)acetonitrile hydrobromide 421-810-4 194602-27-2 - View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active (S)-2,2-diphenyl-2(3-pyrrolidinyl)acetonitrile hydrobromide 421-810-4 194602-27-2 2010 View substance registered dossier
Zach System ZI La Croix Cadeau 49242 Avrillé France France Active (S)-2,2-diphenyl-2(3-pyrrolidinyl)acetonitrile hydrobromide 421-810-4 194602-27-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (S)-2,2-diphenyl-2(3-pyrrolidinyl)acetonitrile hydrobromide 421-810-4 194602-27-2 - View substance registered dossier
DSM Pharma Chemicals Venlo B.V. Grubbenvorsterweg 8 Postbox 81 5900 AB Venlo Netherlands Netherlands Active (S)-2,3-dihydro-1H-indole-2-carboxylic acid 410-860-2 79815-20-6 - View substance registered dossier
Aceto France SAS 3 Rue de Genève CS 50363 BP 50367 Lyon Cedex 06 France France Active (S)-2,3-dihydro-1H-indole-2-carboxylic acid 410-860-2 79815-20-6 2013; 2014 View substance registered dossier
DKSH France S.A. 1475 Quai du Rhone 01702 Miribel France France Active (S)-2,3-dihydro-1H-indole-2-carboxylic acid 410-860-2 79815-20-6 - View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active (S)-2,5-Dihydro-pyrrole-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 873-085-2 74844-93-2 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (S)-2,5-Dihydro-pyrrole-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 873-085-2 74844-93-2 - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Cease Manufacture (S)-2-(1-aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one hydrochloride 942-180-1 - 2017 View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active (S)-2-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid 951-381-3 - 2021 View substance registered dossier
[Confidential] - - - (S)-2-(5-Methylheteromonocycle-2-carboxamido)-alkenoic acid - - - View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom No longer Valid (S)-2-(5-Oxo-3-propyl-1,2-dihydropyrrol-1-yl) butyramide 824-341-7 357338-13-7 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid 439-640-4 109425-51-6 - View substance registered dossier
Roche Pharma AG (1) Emil-Barell-Strasse 1 79639 Grenzach-Wyhlen Germany Germany Cease Manufacture (S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid 439-640-4 109425-51-6 2019 View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active (S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid 439-640-4 109425-51-6 2019; 2020; 2022 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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