Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104978 dossiers.
Substance identity
Administrative data
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Substance data
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Details
(1S,3'R,4'S,5'S,6'R)-6-[(4-ethylphenyl)(hydroxy)methyl]-6'-(hydroxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[2-benzofuran-1,2'-pyran]-3',4',5'-triol
930-239-4 1201913-66-7 Active Intermediate Individual Intermediate use only 13-01-2015 View substance registered dossier
Reaction mass of diammonium sulfate and L-norvaline
930-119-1 - Active Intermediate Joint Intermediate use only 05-08-2015 View substance registered dossier
(1S)-2,3,4,6-tetra-O-acetyl-1,5-anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-D-glucitol
930-010-9 461432-25-7 Active Full Joint ≥ 10 to < 100 tonnes 04-04-2018 View substance registered dossier
Reaction mass of Quartz (SiO2) and glass, oxide, chemicals and mullite and cristobalite
930-007-2 - Active Full Individual ≥ 1 000 to < 10 000 tonnes 27-04-2011 View substance registered dossier
(R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol (R)-acetoxy(phenyl)acetate
929-947-6 - Active Intermediate Joint Intermediate use only 31-10-2017 View substance registered dossier
(R)-2-(3-(diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenol
929-946-0 - Active Intermediate Joint Intermediate use only 05-12-2017 View substance registered dossier
3-(2-Hydroxy-ethyl)-5-methylsulfamoylmethyl-1H-indole-2-carboxylic acid methyl ester
929-941-3 - Active Intermediate Individual Intermediate use only 17-03-2011 View substance registered dossier
2,4-dibromo-1-{[(2-methoxypropan-2-yl)oxy]methyl}benzene
929-928-2 1201913-61-2 Active Intermediate Individual Intermediate use only 10-12-2014 View substance registered dossier
Hexamethylene diisocyanate, oligomers, reaction products with 4-Hydroxybutyl acrylate
929-915-1 - Active Full Joint ≥ 1 to < 10 tonnes 14-05-2018 View substance registered dossier
reaction mass of Reaction mass of Benzeneethanol, 2-chloro-.alpha.-(1-chlorocyclopropyl)-.alpha.-(chloromethyl)- and Oxirane, 2-(1-chlorcyclopropyl)-2-[(2-chlorphenyl)methyl]-
929-889-1 - Active Intermediate Individual Intermediate use only 01-12-2016 View substance registered dossier
2-methyl-4-nitro-1-(4-trifluoromethylsulfanyl-phenoxy)-benzene
929-785-6 - Active Intermediate Joint Intermediate use only 29-10-2018 View substance registered dossier
4-Methoxycarbonyl-2-methylthiophen-3-yl-ammonium hydrochloride
929-732-7 - Active Intermediate Joint Intermediate use only 21-02-2013 View substance registered dossier
3-Methyl-4-(4-trifluoromethylsulfanyl-phenoxy)-phenylamine oxalate
929-675-8 - Active Intermediate Joint Intermediate use only 29-10-2018 View substance registered dossier
1,3-Diazaspiro[4.5]decane-2,4-dione, 8-methoxy-, sodium salt (1:1), cis-
929-513-6 1400584-86-2 Active Intermediate Joint Intermediate use only 24-05-2016 View substance registered dossier
6-benzyloctahydro-1H-pyrrolo[3,4-b]pyridine
929-459-3 - Active Intermediate Individual Intermediate use only 05-05-2011 View substance registered dossier
Reaction mass of isotridecyl 3-mercaptopropionate and isododecyl 3-mercaptopropionate
929-442-0 - Active Intermediate Individual Intermediate use only 11-09-2008 View substance registered dossier
Reaction mass of isotridecyl 3-mercaptopropionate and isododecyl 3-mercaptopropionate
929-442-0 - Active Intermediate Individual Intermediate use only 20-11-2012 View substance registered dossier
[3-Methyl-4-(4-trifluoromethylsulfanyl-phenoxy)-phenyl]-carbamic acid ethyl ester
929-417-4 - Active Intermediate Joint Intermediate use only 29-10-2018 View substance registered dossier
Reaction products of N-(2-aminoethyl)ethane-1,2-diamine and methyl methacrylate and octane-1-thiol
929-305-5 - Active Full Individual ≥ 1 to < 10 tonnes 20-08-2015 View substance registered dossier
4'-Ethyl-2,3-difluorbiphenyl-4-boronic acid
929-209-3 1123312-95-7 Active Full Joint ≥ 10 to < 100 tonnes 22-02-2019 View substance registered dossier
Ethanesulfonic acid, 1-(dimethylamino)-2-hydroxy-, sodium salt (1:1)
929-207-2 1172126-47-4 Active Intermediate Joint Intermediate use only 28-04-2021 View substance registered dossier
5-{4-[(3-chloro-4-{[(3-fluorophenyl)methyl]oxy}phenyl)amino]-6-quinazolinyl}-2-furancarbaldehyde mono(4-methylbenzenesulfonate)
929-151-9 388082-75-5 Active Intermediate Joint Intermediate use only 05-03-2021 View substance registered dossier
Reaction mass of (R)-2-(3-(diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenol and Methylene Chloride
929-144-0 - Active Intermediate Joint Intermediate use only 22-05-2018 View substance registered dossier
1-(2-Chloro-acetyl)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester
929-125-7 - Active Intermediate Joint Intermediate use only 13-08-2018 View substance registered dossier
1-(3-Phenyl-cyclohexyl)-propan-1-one
929-116-8 - Cease Manufacture Intermediate Individual Cease manufacture 11-12-2012 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
[Confidential] - - - (1S,3'R,4'S,5'S,6'R)-6-[(4-ethylphenyl)(hydroxy)methyl]-6'-(hydroxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[2-benzofuran-1,2'-pyran]-3',4',5'-triol 930-239-4 1201913-66-7 - View substance registered dossier
Evonik Fermas s.r.o. Slovenská Ľupča 938 976 13 Slovenská Ľupča Slovakia Slovakia Active Reaction mass of diammonium sulfate and L-norvaline 930-119-1 - - View substance registered dossier
SK BIOTEK IRELAND LIMITED Watery Lane Swords K67 AY91 Swords Co. Dublin Ireland Ireland Active (1S)-2,3,4,6-tetra-O-acetyl-1,5-anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-D-glucitol 930-010-9 461432-25-7 2011; 2015; 2018 View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active (1S)-2,3,4,6-tetra-O-acetyl-1,5-anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-D-glucitol 930-010-9 461432-25-7 2016 View substance registered dossier
Zahna Fliesen GmbH Paul-Utzschneider-Strasse 1 06895 Zahna Germany Germany Active Reaction mass of Quartz (SiO2) and glass, oxide, chemicals and mullite and cristobalite 930-007-2 - 2009; 2011 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol (R)-acetoxy(phenyl)acetate 929-947-6 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (R)-2-(3-(diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenol 929-946-0 - - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active 3-(2-Hydroxy-ethyl)-5-methylsulfamoylmethyl-1H-indole-2-carboxylic acid methyl ester 929-941-3 - 2009; 2011 View substance registered dossier
[Confidential] - - - 2,4-dibromo-1-{[(2-methoxypropan-2-yl)oxy]methyl}benzene 929-928-2 1201913-61-2 - View substance registered dossier
BASF Coatings GmbH Glasuritstrasse 1 Postfach 6123 48136 Münster Nordrhein-Westfalen Germany Germany Active Hexamethylene diisocyanate, oligomers, reaction products with 4-Hydroxybutyl acrylate 929-915-1 - - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active reaction mass of Reaction mass of Benzeneethanol, 2-chloro-.alpha.-(1-chlorocyclopropyl)-.alpha.-(chloromethyl)- and Oxirane, 2-(1-chlorcyclopropyl)-2-[(2-chlorphenyl)methyl]- 929-889-1 - 2010; 2016 View substance registered dossier
CENTIPHARM Chemin de la Madeleine 06131 GRASSE FRANCE France France Active 2-methyl-4-nitro-1-(4-trifluoromethylsulfanyl-phenoxy)-benzene 929-785-6 - - View substance registered dossier
CBW Chemie GmbH Bitterfeld-Wolfen Kühlturmstrasse 3 06803 Bitterfeld-Wolfen / OT Greppin Germany Germany Active 4-Methoxycarbonyl-2-methylthiophen-3-yl-ammonium hydrochloride 929-732-7 - 2013 View substance registered dossier
CENTIPHARM Chemin de la Madeleine 06131 GRASSE FRANCE France France Active 3-Methyl-4-(4-trifluoromethylsulfanyl-phenoxy)-phenylamine oxalate 929-675-8 - - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 1,3-Diazaspiro[4.5]decane-2,4-dione, 8-methoxy-, sodium salt (1:1), cis- 929-513-6 1400584-86-2 - View substance registered dossier
AllessaProduktion GmbH Alt-Fechenheim 34 60386 Frankfurt am Main Germany Germany Cease Manufacture 1,3-Diazaspiro[4.5]decane-2,4-dione, 8-methoxy-, sodium salt (1:1), cis- 929-513-6 1400584-86-2 2020 View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Active 1,3-Diazaspiro[4.5]decane-2,4-dione, 8-methoxy-, sodium salt (1:1), cis- 929-513-6 1400584-86-2 - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 6-benzyloctahydro-1H-pyrrolo[3,4-b]pyridine 929-459-3 - 2011 View substance registered dossier
Bruno Bock Chemische Fabrik GmbH & Co. KG Eichholzer Straße 23 21436 Marschacht Lower Saxony Germany Germany Active Reaction mass of isotridecyl 3-mercaptopropionate and isododecyl 3-mercaptopropionate 929-442-0 - - View substance registered dossier
Bruno Bock Chemische Fabrik GmbH & Co. KG Eichholzer Straße 23 21436 Marschacht Lower Saxony Germany Germany Active Reaction mass of isotridecyl 3-mercaptopropionate and isododecyl 3-mercaptopropionate 929-442-0 - 2011; 2012 View substance registered dossier
CENTIPHARM Chemin de la Madeleine 06131 GRASSE FRANCE France France Active [3-Methyl-4-(4-trifluoromethylsulfanyl-phenoxy)-phenyl]-carbamic acid ethyl ester 929-417-4 - - View substance registered dossier
Baker Hughes (Nederland) B.V Westblaak 89 3012 KG Rotterdam Netherlands Netherlands Active Reaction products of N-(2-aminoethyl)ethane-1,2-diamine and methyl methacrylate and octane-1-thiol 929-305-5 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4'-Ethyl-2,3-difluorbiphenyl-4-boronic acid 929-209-3 1123312-95-7 2019 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active Ethanesulfonic acid, 1-(dimethylamino)-2-hydroxy-, sodium salt (1:1) 929-207-2 1172126-47-4 2021 View substance registered dossier
Thermofisher Scientific Cork Ltd. Currabinny P43 AY66 Carrigaline Co. Cork Ireland Ireland Active 5-{4-[(3-chloro-4-{[(3-fluorophenyl)methyl]oxy}phenyl)amino]-6-quinazolinyl}-2-furancarbaldehyde mono(4-methylbenzenesulfonate) 929-151-9 388082-75-5 2021 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active Reaction mass of (R)-2-(3-(diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenol and Methylene Chloride 929-144-0 - - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active 1-(2-Chloro-acetyl)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester 929-125-7 - - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active 1-(2-Chloro-acetyl)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester 929-125-7 - 2018 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Cease Manufacture 1-(3-Phenyl-cyclohexyl)-propan-1-one 929-116-8 - 2019 View substance registered dossier

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