Registered substances

Registered substances

Registered substances

Please note:

As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
Ethyl 3,4-dihydroxybenzoate
223-529-0 3943-89-3 Active Full Joint ≥ 1 to < 10 tonnes 04-10-2017 View substance registered dossier
Ethyl 3,4-dihydroxybenzoate
223-529-0 3943-89-3 Cease Manufacture Intermediate Joint Cease manufacture 30-11-2015 View substance registered dossier
Ethyl 3,3-bis[(1,1-dimethylpropyl)peroxy]butyrate
LUPEROX 533
403-320-2 67567-23-1 Active NONS Individual Tonnage data confidential 17-12-2010 View substance registered dossier
ethyl 2-{[3-acetylamino-4-(6-bromo-2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-ylazo)phenyl]ethylamino}propionate
430-480-0 221452-67-1 Active NONS Joint Tonnage data confidential 21-09-2010 View substance registered dossier
ethyl 2-{[(2,6-difluorophenyl)methyl](ethoxycarbonyl)amino}-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate
840-148-0 308831-94-9 Active Intermediate Joint Intermediate use only 28-01-2021 View substance registered dossier
ethyl 2-{[(2,6-difluorophenyl)methyl](ethoxycarbonyl)amino}-4-[(dimethylamino)methyl]-5-(4-nitrophenyl)thiophene-3-carboxylate
854-336-5 1589503-97-8 Active Intermediate Joint Intermediate use only 28-01-2021 View substance registered dossier
Ethyl 2-oxopyrrolidine-1-acetate
262-828-0 61516-73-2 Active Intermediate Joint Intermediate use only 25-01-2018 View substance registered dossier
Ethyl 2-oxocyclohexanecarboxylate
216-731-5 1655-07-8 Active Intermediate Joint Intermediate use only 19-06-2018 View substance registered dossier
ethyl 2-oxo-4-phenylpyrrolidine-3-carboxylate
610-841-0 52450-32-5 Active Intermediate Joint Intermediate use only 19-10-2017 View substance registered dossier
Ethyl 2-oxo-4-phenylbutyrate
265-276-9 64920-29-2 Active Intermediate Joint Intermediate use only 19-11-2019 View substance registered dossier
Ethyl 2-naphthyl ether
202-226-7 93-18-5 Active Full Joint ≥ 100 to < 1 000 tonnes 12-04-2022 View substance registered dossier
Ethyl 2-methylvalerate
254-384-1 39255-32-8 Active Full Joint ≥ 100 to < 1 000 tonnes 03-11-2021 View substance registered dossier
Ethyl 2-methylpenta-3,4-dienoate
262-278-1 60523-21-9 Active Intermediate Joint Intermediate use only 17-05-2018 View substance registered dossier
Ethyl 2-methylcrotonate
227-425-6 5837-78-5 Active Intermediate Individual Intermediate use only 18-10-2017 View substance registered dossier
Ethyl 2-methylbutyrate
231-225-4 7452-79-1 Active Full Joint ≥ 1 000 to < 10 000 tonnes 16-03-2022 View substance registered dossier
Ethyl 2-methylbut-3-enoate
700-224-5 1647-12-7 Active Intermediate Joint Intermediate use only 08-09-2010 View substance registered dossier
ETHYL 2-METHYL-4-PENTANOATEETH OXANOATE-369 CRUDE
- - Active Full Joint ≥ 1 to < 10 tonnes 20-05-2022 View substance registered dossier
Ethyl 2-methyl-4-oxo-6-pentylcyclohex-2-ene-1-carboxylate
261-629-6 59151-19-8 Active Full Joint ≥ 1 to < 10 tonnes 10-03-2017 View substance registered dossier
Ethyl 2-methyl-2-butenoate
259-688-8 55514-48-2 Active Intermediate Individual Intermediate use only 18-10-2017 View substance registered dossier
Ethyl 2-methyl-1,3-dioxolane-2-acetate
229-114-0 6413-10-1 Active Full Joint ≥ 100 to < 1 000 tonnes 08-03-2022 View substance registered dossier
Ethyl 2-hydroxy-3-methylbut-3-enoate
EVERNOTE
445-780-7 33537-17-6 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
Ethyl 2-formamido-α-oxothiazol-4-acetate
265-299-4 64987-03-7 Active Intermediate Joint Intermediate use only 20-05-2021 View substance registered dossier
Ethyl 2-ethylhexanoate
221-043-3 2983-37-1 Active Full Joint ≥ 1 to < 10 tonnes 03-07-2017 View substance registered dossier
Ethyl 2-ethoxy-4-carboxymethylbenzoate
ECPA
427-630-2 99469-99-5 Active NONS Joint Tonnage data confidential 20-12-2013 View substance registered dossier
Ethyl 2-ethoxy-4-carboxymethylbenzoate
ECPA
427-630-2 99469-99-5 Active Intermediate Joint Intermediate use only 07-12-2017 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Agfa-Gevaert N.V. Septestraat 27 2640 Mortsel Belgium Belgium Active Ethyl 3,4-dihydroxybenzoate 223-529-0 3943-89-3 - View substance registered dossier
Chemosyntha BV Stedestraat 51 B-8530 Harelbeke West Vlaanderen Belgium Belgium Active Ethyl 3,4-dihydroxybenzoate 223-529-0 3943-89-3 - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Cease Manufacture Ethyl 3,4-dihydroxybenzoate 223-529-0 3943-89-3 2018 View substance registered dossier
ARKEMA Gmbh Tersteegenstrasse 28 40401 Düsseldorf Germany Germany Active Ethyl 3,3-bis[(1,1-dimethylpropyl)peroxy]butyrate 403-320-2 67567-23-1 2010 View substance registered dossier
Huntsman Textile Effects (Germany) GmbH Rehlinger Str. 1 D-86462 Langweid a.Lech Germany Germany Active ethyl 2-{[3-acetylamino-4-(6-bromo-2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-ylazo)phenyl]ethylamino}propionate 430-480-0 221452-67-1 2010 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active ethyl 2-{[3-acetylamino-4-(6-bromo-2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-ylazo)phenyl]ethylamino}propionate 430-480-0 221452-67-1 - View substance registered dossier
Fareva La Vallée 928 avenue Lavoisier ZI de Blavozy 43700 Saint Germain Laprade Auvergne France France Active ethyl 2-{[(2,6-difluorophenyl)methyl](ethoxycarbonyl)amino}-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate 840-148-0 308831-94-9 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active ethyl 2-{[(2,6-difluorophenyl)methyl](ethoxycarbonyl)amino}-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate 840-148-0 308831-94-9 2021 View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active ethyl 2-{[(2,6-difluorophenyl)methyl](ethoxycarbonyl)amino}-4-[(dimethylamino)methyl]-5-(4-nitrophenyl)thiophene-3-carboxylate 854-336-5 1589503-97-8 2021 View substance registered dossier
Fareva La Vallée 928 avenue Lavoisier ZI de Blavozy 43700 Saint Germain Laprade Auvergne France France Active ethyl 2-{[(2,6-difluorophenyl)methyl](ethoxycarbonyl)amino}-4-[(dimethylamino)methyl]-5-(4-nitrophenyl)thiophene-3-carboxylate 854-336-5 1589503-97-8 - View substance registered dossier
FERRANIA CHEMICALS S.R.L. Viale della Libertà, 57 17014 Cairo Montenotte (SV) Italy Italy Active Ethyl 2-oxopyrrolidine-1-acetate 262-828-0 61516-73-2 - View substance registered dossier
PMC ISOCHEM 32 rue Lavoisier 91710 VERT LE PETIT France France Active Ethyl 2-oxocyclohexanecarboxylate 216-731-5 1655-07-8 - View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Active Ethyl 2-oxocyclohexanecarboxylate 216-731-5 1655-07-8 2018 View substance registered dossier
JSC "Olainfarm" Rupnicu str. 5 LV-2114 Olaine Latvia Latvia Active ethyl 2-oxo-4-phenylpyrrolidine-3-carboxylate 610-841-0 52450-32-5 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active Ethyl 2-oxo-4-phenylbutyrate 265-276-9 64920-29-2 2019 View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active Ethyl 2-naphthyl ether 202-226-7 93-18-5 - View substance registered dossier
LLUCH ESSENCE, S.L.U. Lo Gaiter, 160 08820 EL PRAT DE LLOBREGAT CATALUÑA Spain Spain Active Ethyl 2-naphthyl ether 202-226-7 93-18-5 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED (Jiangxi Zhangshu Crown Capital Fragrance Ltd.) Room 002, Regus Harcourt Centre D02 HW77, D02 Dublin Ireland Ireland Active Ethyl 2-naphthyl ether 202-226-7 93-18-5 - View substance registered dossier
DESTILACIONES BORDAS CHINCHURRETA, S.A. C/ Acueducto, 4-6 Pol. Ind. Ctra la Isla 41703 Dos Hermanas (Sevilla) Spain Spain Active Ethyl 2-naphthyl ether 202-226-7 93-18-5 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active Ethyl 2-naphthyl ether 202-226-7 93-18-5 2017; 2018 View substance registered dossier
R.C.Treatt & Co. Ltd. Northern Way IP32 6NL Bury St. Edmunds Suffolk United Kingdom United Kingdom No longer Valid Ethyl 2-naphthyl ether 202-226-7 93-18-5 2021 View substance registered dossier
Cambridge Environmental Assessments, part of RSK ADAS Europe(Ireland) Ltd Office Suite B, Bluebell Business Centre Old Naas Road, DB12XV7K Dublin Ireland Ireland Active Ethyl 2-methylvalerate 254-384-1 39255-32-8 2015; 2020 View substance registered dossier
Intertek Deutschland GmbH IBVC Stangenstr. 1 70771 Leinfelden-Echterdingen Germany Germany Active Ethyl 2-methylvalerate 254-384-1 39255-32-8 2021 View substance registered dossier
ERNESTO VENTOS, S.A. Carretera Reial 120B 08960 Sant Just Desvern Spain Spain Active Ethyl 2-methylvalerate 254-384-1 39255-32-8 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 Dublin Ireland Ireland Active Ethyl 2-methylvalerate 254-384-1 39255-32-8 - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active Ethyl 2-methylpenta-3,4-dienoate 262-278-1 60523-21-9 - View substance registered dossier
Miltitz Aromatics GmbH Chemiepark Bitterfeld-Wolfen Riechstoffstrasse 1 06803 Bitterfeld-Wolfen Germany Germany Active Ethyl 2-methylcrotonate 227-425-6 5837-78-5 - View substance registered dossier
Cambridge Environmental Assessments, part of RSK ADAS Europe(Ireland) Ltd Office Suite B, Bluebell Business Centre Old Naas Road, DB12XV7K Dublin Ireland Ireland Active Ethyl 2-methylbutyrate 231-225-4 7452-79-1 2015; 2017; 2020 View substance registered dossier
WSP Deutschland A.G. (OR10) Dingolfinger Straße 1-15 81673 München Germany Germany Active Ethyl 2-methylbutyrate 231-225-4 7452-79-1 - View substance registered dossier
Bell Flavors & Fragrances GmbH Schimmelstr. 1 04205 Leipzig Germany Germany Active Ethyl 2-methylbutyrate 231-225-4 7452-79-1 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active Ethyl 2-methylbutyrate 231-225-4 7452-79-1 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 Dublin Ireland Ireland Active Ethyl 2-methylbutyrate 231-225-4 7452-79-1 - View substance registered dossier
REACH24H CONSULTING GROUP Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active Ethyl 2-methylbutyrate 231-225-4 7452-79-1 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active Ethyl 2-methylbutyrate 231-225-4 7452-79-1 - View substance registered dossier
Symrise A4 Av. República Mexicana 200 Col. Garza Cantú 66480 San Nicolás de los Garza N.L. Mexico Germany Germany Active Ethyl 2-methylbutyrate 231-225-4 7452-79-1 - View substance registered dossier
AXXENCE Aromatic GmbH Tackenweide 28 46446 Emmerich am Rhein NRW Germany Germany Active Ethyl 2-methylbutyrate 231-225-4 7452-79-1 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active Ethyl 2-methylbutyrate 231-225-4 7452-79-1 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Ethyl 2-methylbut-3-enoate 700-224-5 1647-12-7 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active Ethyl 2-methylbut-3-enoate 700-224-5 1647-12-7 2009; 2010 View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active ETHYL 2-METHYL-4-PENTANOATEETH OXANOATE-369 CRUDE - - - View substance registered dossier
Givaudan Iberica SA Pla d'en Batlle s/n 08470 San Celoni Barcelona Spain Spain Active Ethyl 2-methyl-4-oxo-6-pentylcyclohex-2-ene-1-carboxylate 261-629-6 59151-19-8 - View substance registered dossier
Miltitz Aromatics GmbH Chemiepark Bitterfeld-Wolfen Riechstoffstrasse 1 06803 Bitterfeld-Wolfen Germany Germany Active Ethyl 2-methyl-2-butenoate 259-688-8 55514-48-2 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active Ethyl 2-methyl-1,3-dioxolane-2-acetate 229-114-0 6413-10-1 2020 View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active Ethyl 2-methyl-1,3-dioxolane-2-acetate 229-114-0 6413-10-1 2014; 2019 View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active Ethyl 2-methyl-1,3-dioxolane-2-acetate 229-114-0 6413-10-1 - View substance registered dossier
Symrise A4 Av. República Mexicana 200 Col. Garza Cantú 66480 San Nicolás de los Garza N.L. Mexico Germany Germany Active Ethyl 2-methyl-1,3-dioxolane-2-acetate 229-114-0 6413-10-1 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active Ethyl 2-methyl-1,3-dioxolane-2-acetate 229-114-0 6413-10-1 - View substance registered dossier
INDUKERN, S.A.U. Alta Ribagorza, 6-8 08820 El Prat de Llobregat Barcelona Spain Spain Active Ethyl 2-methyl-1,3-dioxolane-2-acetate 229-114-0 6413-10-1 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active Ethyl 2-methyl-1,3-dioxolane-2-acetate 229-114-0 6413-10-1 - View substance registered dossier
Penman Consulting bvba 15 Avenue des Arts 10 B-1210 Brussels Belgium Belgium Active Ethyl 2-methyl-1,3-dioxolane-2-acetate 229-114-0 6413-10-1 2022 View substance registered dossier
ERNESTO VENTOS, S.A. Carretera Reial 120B 08960 Sant Just Desvern Spain Spain Active Ethyl 2-methyl-1,3-dioxolane-2-acetate 229-114-0 6413-10-1 - View substance registered dossier
- - - - Ethyl 2-hydroxy-3-methylbut-3-enoate 445-780-7 33537-17-6 - View substance registered dossier
Sumitomo Deutschland GmbH Schwannstraße 10 40476 Düsseldorf Germany Germany Cease Manufacture Ethyl 2-formamido-α-oxothiazol-4-acetate 265-299-4 64987-03-7 2021 View substance registered dossier
Summit Pharmaceuticals Europe S.r.l. Viale Piero e Alberto Pirelli, 6 20126 Milano Italy Italy Active Ethyl 2-formamido-α-oxothiazol-4-acetate 265-299-4 64987-03-7 2021 View substance registered dossier
Kao Chemicals Europe, S.L. (2) Puig dels Tudons, 10 08210 Barbera del Valles Barcelona Spain Spain Active Ethyl 2-ethylhexanoate 221-043-3 2983-37-1 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active Ethyl 2-ethoxy-4-carboxymethylbenzoate 427-630-2 99469-99-5 2012; 2013 View substance registered dossier
Zach System ZI La Croix Cadeau 49242 Avrillé France France Active Ethyl 2-ethoxy-4-carboxymethylbenzoate 427-630-2 99469-99-5 - View substance registered dossier
Midas Pharma GmbH Rheinstrasse 49 55218 Ingelheim Germany Germany Active Ethyl 2-ethoxy-4-carboxymethylbenzoate 427-630-2 99469-99-5 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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