Registration Dossier
Registration Dossier
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EC number: 950-052-1 | CAS number: -
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Description of key information
No clinical signs or effects on reproduction or development were reported.
The No Observed Adverse Effect Level (NOAEL) for repeated dose toxicity, reproductive toxicity and for developmental toxicity was considered to be in excess of 1000 mg/kg bw/day zirconium acetate anhydrous.
This equates to ca. 280 mg/kg/day Zr 4+ and in turn, using a nominal molecular weight of 231 for the registered substance, the NOAEL for the zirconium hydroxysulphate is greater than 700 mg/kg/day
Effect on fertility: via oral route
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- NOAEL
- 700 mg/kg bw/day
- Study duration:
- subacute
- Species:
- rat
Justification for classification or non-classification
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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