Reaction products of acrylic acid with 2,2'-[oxybis(methylene)]bis[2-ethylpropane-1,3-diol]

Toxicity to soil microorganisms

Administrative data

Endpoint:

toxicity to soil microorganisms

Data waiving:

other justification

Justification for data waiving:

other:

Cross-reference

Cross-reference 1

Reason / purpose for cross-reference:

data waiving: supporting information

Cross-reference 2

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Using the HPLC method at neutral pH and soil-adsorption-reference data, the log Koc of di-TMPTTA for the major component was determined to be 3.61. The minor components had log Koc values between < 1.26 and > 5.63.

The upper limit log Koc value of 3.61 (Koc: 4000) for the major constituents representing ≥60% of the UVCB substance composition has been considered further for risk assessment.

Koc at 20 °C:

4 000

The HPLC method at neutral pH using soil-adsorption reference data was applied for the determination of the adsorption coefficient of di-TMPTTA in accordance with OECD Guideline 121 and EU Method C.9. The mobile phase was 55/45 (v/v) methanol/water. The column temperature was 35°C. In the HPLC chromatogram, one major peak (66% peak area) and 23 smaller peaks (0.02 - 11% peak area) were observed. The log Koc value for the major component was 3.61 (Koc: 4,000). The log Koc values for the minor components ranged from < 1.26 to > 5.63 (Koc from < 18 to > 4.3E+5) (Lammers 2013).

The upper limit log Koc value of 3.61 (Koc: 4000) for the major constituents representing ≥60% of the UVCB substance composition has been considered further for risk assessment. No further supporting data (e.g., using QSAR) has been generated, as the value already exceeds the threshold of 3, indicating a high soil adsorption potential leading to worst case risk assessment.