Esterification products of alkenylsuccinic anhydride and 2-dialkylaminoethanol

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

14th January 1993 to 18th May 1994

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

no

GLP compliance:

yes

Type of method:

flask method

Key result

Temp.:

20 °C

Remarks on result:

not determinable

Remarks:

the substance formed a stable emulsion throughout the concentration range of 6 to 10000 g/L

Details on results:

The water solubility of the test material could not be determined. The test material formed a stable emulsion in water.
The critical micelle concentration (CMC) was not determined.

Table 1: Results from run 1 (Addition of test material to 10 mL of water)

Weight of test substance (mg)	Concentration (mg/mL)	Observations
60	6	After stirring, a foam formed
460	52	Foam took on colour of test substance, some residual test substance
350	87	Agter standing one hour, no water remained, only foam
460	133	After mixing, foam thickened.
3110	444	Thickening continued
With further test substance additions up to approximately 10 g (1000 mg/mL) the foam continued to thicken and remain stable.

 

Table 2: Addition of water to 10.17 g of test material

Incremental volume of water adder (mL)	Concentration (mg/mL)	Observations
0.1 (up to 1 mL total)	≥ 10170	Water 'absorbed' by test substance
1	10170	Cloudy mixture
1	5085	Liquid coloured at test substance plus white foam
2	2543	No change from above after one hour
With increasing water additions, foam continued to form, with presence of some residual test material

Conclusions:

The shake flask method was used to attempt to produce saturated solutions of the test material in water. It was not possible at the test substance formed a stable emulsion throughout the concentration range of 6 to 10000 g/L.

Executive summary:

The water solubility of the test material was determined in a study conducted in accordance with EU Method A.6 and OECD Guideline 105. The study was performed using the shake flask method. It was not possible to determine the water solubility from the current study as the test substance formed a stable emulsion throughout the concentration range of 6 to 10000 g/L. The critical micelle concentration (CMC) was not determined.

Description of key information

The water solubility of the test material was determined in a study conducted in accordance with EU Method A.6 and OECD Guideline 105. The study was performed using the shake flask method. It was not possible to determine the water solubility from the current study as the test substance formed a stable emulsion throughout the concentration range of 6 to 10000 g/L. The critical micelle concentration (CMC) was not determined.