Registration Dossier
Registration Dossier
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EC number: 947-988-8 | CAS number: -
Solubility in organic solvents / fat solubility
Administrative data
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- between 09 August 2017 and 30 November 2017
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- This test is only performed to give an impression of the solubility of Monothioglycerol (TG) in different organic solvents. It does not claim to determine exact solubility in g/L.
- GLP compliance:
- no
- Other quality assurance:
- other: ISO 9001:2008
Test material
- Reference substance name:
- 3-mercaptopropane-1,2-diol
- EC Number:
- 202-495-0
- EC Name:
- 3-mercaptopropane-1,2-diol
- Cas Number:
- 96-27-5
- Molecular formula:
- C3H8O2S
- IUPAC Name:
- 3-sulfanylpropane-1,2-diol
- Test material form:
- liquid: viscous
Constituent 1
Results and discussion
Solubility in organic solvents / fat solubilityopen allclose all
- Key result
- Medium:
- other: n-hexane
- Solubility:
- < 0.1 g/L
- Temp.:
- 20 °C
- Key result
- Medium:
- acetonitrile
- Solubility:
- > 1 000 g/L
- Temp.:
- 20 °C
- Key result
- Medium:
- ethanol
- Solubility:
- > 1 000 g/L
- Temp.:
- 20 °C
- Test substance stable:
- not determined
Applicant's summary and conclusion
- Conclusions:
- Based on the definition in the European Pharmacopoeia, Monothioglycerol (TG) is infinitely soluble in Acetonitrile, infinitely soluble in Ethanol and insoluble in Hexane
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