Registration Dossier
Registration Dossier
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EC number: 823-780-1 | CAS number: 1034820-43-3
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No toxic effects occur up to the water solubility.
EC50 (24h) = 11 mg/l (nominal)
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 11 mg/L
Additional information
The evaluation of the toxicity potential of the substance to aquatic invertebrates was done by the assessment of the experimental data on Similar Substance 01. No experimental data are available for the (target) substance. Justification for Read Across is given in Section 13 of IUCLID.
The substance was tested in a non-GLP guideline study according to OECD 202. The mobility of Daphnia magna was assessed after 24 hours of exposure to different concentrations of the substance under static conditions.
Twenty Daphnia magna were exposed to the Similar Substance 01 at 3.2, 5.8, 10, 18, 32 mg/l (nominal). The respective EC0 at 24h was < 3.2 mg/l, the EC100 was 18 mg/l and the EC50 = 11 mg/l. All three values are based on nominal concentrations, which were verified by analytical determinations. The compound was initially suspended in alkylphenol polyglycolether and tetrahydrofuran and dispersed in water. The test compound was present as a suspension and a precipitate formed shortly after the start of the test at concentrations between 3.2 and 32 mg/l.
The EC values obtained represent a worst-case assumption where water solubility is achieved by excessive use of solvent.
The target substance is expected to have similar effects on the aquatic invertebrates and is thus considered to not have any toxic effects up to the limit of water solubility.
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