Resinoid of Boswellia Carterii (Burseraceae) obtained from exudate by ethanol extraction

Density

Link to relevant study record(s)

Reference

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

13 November 2017 - 15 December 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

The study was conducted according to an internationally recognised method. Test substance is adequately characterised. Therefore full validation applies.

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Version / remarks:

2012

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Version / remarks:

2008

Deviations:

no

Principles of method if other than guideline:

Not applicable

GLP compliance:

yes (incl. QA statement)

Remarks:

Inspected on 13 and 14 October 2014/ Signed on 8 April 2015

Type of method:

pycnometer method

Key result

Type:

relative density

Density:

1.091 other: no dimension

Temp.:

20 °C

All measured values are given in the following table:

First Determination
Weighing #	m1	m2	m3	m4	m5
Item	Pycn. empty	Pycn.+ H2O	Pycn. + repl.liq.	Pycn. + test item	Pycn. + test item + repl. liq.
Mass in g	38.0029	88.3649	88.3754	46.3071	89.0906
Temperature in °C	19.8	20.0	20.0	20.0	19.8
Second Determination
Weighing #	m1	m2	m3	m4	m5
Item	Pycn. empty	Pycn.+ H2O	Pycn. + repl.liq.	Pycn. + test item	Pycn. + test item + repl. liq.
Mass in g	38.0038	88.3681	88.3765	46.7819	89.1144
Temperature in °C	20.0	20.2	20.0	20.0	19.6

The following values were calculated:

First Determination			Error rel.	Error abs.
Temperature	20.0	°C		0.1
Density of water	0.998203	g/cm^3	2.00%	0.0002
Volume of Pycnometer	50.4527	cm^3
Density of Replacement Liquid	0.9984	g/cm^3
Density of Test Item	1.0925	g/cm^3	0.0254%	0.0003
Second Determination			Error rel.	Error abs.
Temperature	20.2	°C		0.1
Density of water	0.998203	g/cm^3	2.00%	0.0002
Volume of Pycnometer	50.4550	cm^3
Density of Replacement Liquid	0.9984	g/cm^3
Density of Test Item	1.0900	g/cm^3	0.0241%	0.0003

Results - mean value:

Parameter	Value	Unit	Standard Deviation	Relative Standard Deviation
Volume of Pycnometer	50.45	cm^3	0.0016	0.00 %
Density of Test Item	1.0912	g/cm^3	0.0018	0.16 %
Density of Test Item	1091.2	kg/m^3	1.8	0.16 %
Relative Density of Test Item	1.0912		0.0018	0.16 %

The density of the test item was calculated as 1.0912 ± 0.0003 g/cm³at 20.0 ± 0.4°C with the maximum error of a single determination.

Conclusions:

The density of the test item was calculated as 1.0912 ± 0.0003 g/cm3 at 20.0 ± 0.4 °C with the maximum error of a single determination.
Standard deviation was 0.0018 g/cm3, showing good correlation of the two determinations.

Executive summary:

The study was performed in order to determine the density of test item according to OECD 109, resp. EU A.3 guideline, using a pycnometer.

The density of the test item was calculated as 1.0912 ± 0.0003 g/cm3 at 20.0 ± 0.4 °C.

Description of key information

Using the pycnometer method, a density of 1.0912 ± 0.0003 g/cm3 at 20 ± 0.4 °C was measured. This value is the mean of two independent determinations.

Key value for chemical safety assessment

Relative density at 20C:

1.091

Additional information

A fully reliable experimental study, conducted according to OECD 109 /EU A3 guideline, using pycnometer, is available. It is considered as a key study, and the result is retained as key data.