Registration Dossier
Registration Dossier
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EC number: 701-083-2 | CAS number: -
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Short description of key information on absorption rate using the closely related substance MEA polyborate (EC 247-421-8):
Rat, mouse, rabbit and human skin were administered nominal doses of 4 mg/cm² of undiluted or aqueous MEA in vitro. Mean dermal absorption values after 6 hours were 5.98,16.92, 8.66 and 0.61% (undiluted MEA) and 1.32, 24.79, 1.87 and 1.11% (aqueous MEA), respectively for rat, mouse, rabbit and human skin. It is appropriate to utilise the highest dermal absorption value for human skin to be conservative in risk assessment. Therefore, a dermal absorption value of 1.11% in aqueous MEA has been identified for human skin.
Key value for chemical safety assessment
- Absorption rate - dermal (%):
- 1.1
Additional information
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