Registration Dossier
Registration Dossier
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EC number: 943-537-4 | CAS number: -
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
The main functional groups within the components of the test item are an ester and an amine. Although esters usually hydrolyse readily, especially in alkaline solutions, the test item components may have a significantly reduced hydrolytic rate due to them being essentially insoluble in water. The amine group will be stable. There is also a small amount of amide and alcohol groups. Amides are more hydrolytically stable than the ester, whilst the alcohol will be hydrolytically stable. Overall, these issues make hydrolysis testing unfeasible and testing was not carried out using Method 111 of the OECD Guidelines for Testing of Chemicals (13 April 2004) and Method C.7 Abiotic Degradation, Hydrolysis as a Function of pH of Commission Regulation (EC) No 440/2008 of 30 May 2008.
Key value for chemical safety assessment
Additional information
The test item as a whole was expected to be essentially insoluble in water. Therefore the test solution concentration required to dissolve all the components (less than half the water solubility) would be impractically low and a sufficiently sensitive analytical method was not available. The test item is a complex mixture, to which the test method is not ideally suited because each component that is unstable is likely to have its own hydrolytic rate.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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