4-Ethyl-2’-fluoro-4’-bromobiphenyl

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2019-03-05

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

GLP compliance:

no

Type of method:

differential scanning calorimetry

Key result

Boiling pt.:

>= 328 - <= 330 °C

Atm. press.:

1 013.25 hPa

Decomposition:

no

Boiling point / boiling range; DSC measurement

Two DSC measurements in aluminium crucibles with a hole showed an endothermal effect after the melting in the temperature range of 305 - 345 °C. The onset temperature was derived from the intersection of the tangent line with the highest slope of the endothermal peak with the baseline. No further endothermic or exothermic effects were observed up to the final temperature. The mass loss after the DSC measurements amounted to 100 %.

Boiling point (DSC measurement)

Ident No.	Test item / mg	Starting temperature / °C	Final test temperature/ °C	Temperature range (endo- thermal) / °C	Onset (boiling) / °C	Crucible	Observations after the measurement
38536	12.31	25	500	305 - 345	328.80	Aluminium with a hole	Empty crucible, mass loss: 100%
38538	16.09	25	400	315-345	329.92	Aluminium with a hole	Empty crucible, mass loss: 100%

 

The test item had a boiling range of 328 - 330 °C.

Conclusions:

The test item has a boiling ranget at atmospheric pressure (1013.3 hPa) from 328 - 330 °C.

Executive summary:

A study was conducted according to OECD TG 103 and Regulation (EC) No 440/2008 method A.2 to determine the boiling point of the test item using differential scanning calorimetry.The test item was weighed out into an aluminium crucible under an inert atmosphere (nitrogen). Two tests with about 12 – 16 mg of the test item were performed. As reference crucible, an empty aluminium crucible was used. Two DSC measurements in aluminium crucibles with a hole showed an endothermal effect after the melting in the temperature range of 305 - 345 °C. The onset temperature was derived from the intersection of the tangent line with the highest slope of the endothermal peak with the baseline. No further endothermic or exothermic effects were observed up to the final temperature (500 °C). The mass loss after the DSC measurements amounted to 100 %. The correction of the boiling temperature to standard pressure was performed according to H.N. Hass and R.F. Newton. The test item boiling range was determined to be 328-330 °C at 1013.3 hPa.

Description of key information

The test item has a boiling ranget at atmospheric pressure (1013.3 hPa) from 328 - 330 °C.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

328 °C

Additional information

A study was conducted according to OECD TG 103 and Regulation (EC) No 440/2008 method A.2 to determine the boiling point of the test item using differential scanning calorimetry (reference 4.3 -1). The test item was weighed out into an aluminium crucible under an inert atmosphere (nitrogen). Two tests with about 12 – 16 mg of the test item were performed. As reference crucible, an empty aluminium crucible was used. Two DSC measurements in aluminium crucibles with a hole showed an endothermal effect after the melting in the temperature range of 305 - 345 °C. The onset temperature was derived from the intersection of the tangent line with the highest slope of the endothermal peak with the baseline. No further endothermic or exothermic effects were observed up to the final temperature (500 °C). The mass loss after the DSC measurements amounted to 100 %. The correction of the boiling temperature to standard pressure was performed according to H.N. Hass and R.F. Newton. The test item boiling range was determined to be 328-330 °C at 1013.3 hPa.