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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report date:
2015

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
2-methoxy-5-nitrophenyl acetate
Cas Number:
53606-41-0
Molecular formula:
C9H9NO5
IUPAC Name:
2-methoxy-5-nitrophenyl acetate
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder
Details on test material:
- Name of test material (as cited in study report): 2-Methoxy-5-Nitrophenyl Acetate
- Physical state: solid
- Analytical purity: more than 95 %

- Lot/batch No.: 102014
- Expiration date of the lot/batch: unlisted

- Stability under test conditions: unlisted
- Storage condition of test material: The test substance was stored in closed container in dark and dry at the room temperature.

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
1.487
Temp.:
25 °C
pH:
6.72

Applicant's summary and conclusion

Conclusions:
Partition coefficient (log P) of the test substance (2-Methoxy 5-Nitrophenyl Acetate) is: log P = 1.49 +- 0.43 (25 °C, pH = 6.72)
Executive summary:

The partition coefficient of the test substance (2-Methoxy-Nitrophenyl Acetate) was determined. Based on the results of the preliminary estimation of the partition coefficient by a calculation method, the HPLC method was used for the main experiment.

The procedure was performed according to Method A.8. – Partition Coefficient, Council Regulation (EC) No.440/2008, Published in O.J. L 142, 2008.

Partition coefficient (log P) of the test substance (2-Methoxy 5-Nitrophenyl Acetate) is:

log P = 1.49 +- 0.43 (25 °C, pH = 6.72)