Registration Dossier
Registration Dossier
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EC number: 942-835-1 | CAS number: -
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
- EC50 for microorganisms:
- 430 mg/L
- EC10 or NOEC for microorganisms:
- 38 mg/L
Additional information
A study was performed to assess the effect of the test item on the respiration of activated sewage sludge. The method followed was designed to be compatible with the OECD Guidelines for Testing of Chemicals (2010) No. 209 "Activated Sludge, Respiration Inhibition Test (Carbon and Ammonium Oxidation)".
Following a preliminary range-finding test, activated sewage sludge was exposed to an aqueous solution of the test item at concentrations of 3.2, 10, 32, 100 and 320 mg/L (5 replicates) for a period of 3 hours at temperatures of between 19 and 20 °C with the addition of a synthetic sewage as a respiratory substrate. The rate of respiration was determined after 3 hours contact time and compared to data for the control and a reference item, 3,5-dichlorophenol.
The effect of the test item on the respiration of activated sewage sludge gave a 3-Hour EC10 value of 38 mg/L and a 3-Hour EC50 value of 430 mg/L · The No Observed Effect Concentration (NOEC) after 3 hours exposure was 10 mg/L. The reference item gave a 3-Hour EC50 value of 6.0 mg/L, 95% confidence limits 4.5 - 8.0 mg/L.
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