Amidation products of C16-18 (even numbered), C18 unsaturated fatty acids esters with 1,1'-iminodipropan-2-ol

pH

Administrative data

Endpoint:

pH

Type of information:

experimental study

Adequacy of study:

key study

Study period:

22 June 2016 to 14 October 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2016

Report date:

2016

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 122 (Determination of pH, Acidity and Alkalinity)

Version / remarks:

Organization for Economic Co-operation and Development (OECD), OECD Guideline for the Testing of Chemicals no. 122: “Determination of pH, Acidity and Alkalinity”, 26 July 2013.

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7000 (pH)

Version / remarks:

United States Environmental Protection Agency (EPA), Product Properties Test Guidelines no. OPPTS 830.7000: "pH", August 1996.

Deviations:

no

Test guideline 3

Qualifier:

according to guideline

Guideline:

CIPAC MT 75 (Determination of pH Values)

Version / remarks:

CIPAC, Analysis of Technical and Formulated Pesticides, MT 75.3: “Determination of pH values”, CIPAC Handbook Volume J, 2000.

Deviations:

no

GLP compliance:

yes

Test material

Test material information

Constituent 1

Reference substance name:

Amidation products of C16-18 (even numbered), C18 unsaturated fatty acids esters with 1,1'-iminodipropan-2-ol

EC Number:

701-003-6

Cas Number:

1454803-04-3

Molecular formula:

C20H39NO3 to C26H51NO3

IUPAC Name:

Amidation products of C16-18 (even numbered), C18 unsaturated fatty acids esters with 1,1'-iminodipropan-2-ol

Test material form:

liquid

Details on test material:

Identification: MLA-3202
Appearance: Clear amber-red liquid
Purity/Composition: UVCB
Test item storage: At room temperature
Stable under storage conditions until 17 February 2019 (expiry date)
Purity/composition correction factor: No correction factor required
Chemical name (IUPAC), synonym or trade name: Amides, tallow, N,N-bis(2-hydroxypropyl)
CAS Number: 1454803-04-3
Test item handling No specific handling conditions required

Specific details on test material used for the study:

Batch: RC-1045Study specific test item informationPurity/composition correction factor: No correction factor requiredChemical name (IUPAC), synonym or trade name: Amides, tallow, N,N-bis(2-hydroxypropyl)CAS Number: 1454803-04-3Test item handling: No specific handling conditions required

Reagents

Reagent:

other: Double distilled water; Potassium hydrogen phthalate; Di-sodium tetraborate decahydrate; buffer solutions

Results and discussion

pH value

Key result

pH value:

6.5

Temp.:

23.2 °C

Concentration:

100 vol%

Any other information on results incl. tables

pH of the test item

	pH
	Test item	1% (w/v) mixture
	6.495 6.561	4.693 4.671
Mean	6.5	4.7

 

Applicant's summary and conclusion

Conclusions:

The pH of the test item was 6.5.The pH of the 1% (w/v) aqueous mixtures was 4.7.

Executive summary:

The purpose of the study was to determine the physico-chemical properties for MLA-3202.

 

The pH of the undiluted test item and of 1% (w/v) aqueous mixtures of the test item was measured using a 906 Titrando, in accordance with the following guidelines:

CIPAC, Analysis of Technical and Formulated Pesticides, MT 75.3: “Determination of pH values”, CIPAC Handbook Volume J, 2000.

Organization for Economic Co-operation and Development (OECD), OECD Guideline for the Testing of Chemicals no. 122: “Determination of pH, Acidity and Alkalinity”, 26 July 2013.

United States Environmental Protection Agency (EPA), Product Properties Test Guidelines no. OPPTS 830.7000: "pH", August 1996.

 

The pH of two 1% (w/v) mixtures of the test item in double distilled water was measured using a 906 Titrando (Metrohm, Herisau, Switzerland) and a combined glass electrode (glass glass electrode and reference electrode, Metrohm). Also the pH of the undiluted test item will be measured in duplicate.

The pH meter wa calibrated using a 0.05 M potassium hydrogen phthalate buffer solution (pH 4.00) and a 0.05 M di-sodium tetraborate buffer solution (pH 9.22 at 20°C).

At the start and at the end of the measurements, pH of these buffer solutions was measured to ensure proper performance of the pH meter.

For the preparation of the 1% (w/v) mixtures, accurately weighed amounts of 1.0006 g and 1.0009 g of the test item were transferred into a 100 mL measuring cylinder, containing about 50 mL water. The volume was made up to 100 mL with water, the cylinder was stoppered and the dispersion was shaken vigorously by hand until completely mixed or dispersed. After it was left to stand for 1 minute, the combined glass electrode was immersed into the liquid and the pH was measured without stirring. The pH value was recorded after 1 and 2 minutes.

Because the pH value changed more than 0.1 unit during this equilibration time, the pH was also recorded 10 minutes after immersion of the electrode.

The pH of the undiluted test item was determined directly. The electrode was immersed into the test item and the pH value was recorded after 1 and 2 minutes.

 

The 1% (w/v) mixtures of the test item in double distilled water were opaque white suspensions with approximately 5 mL white foam.

 

The pH of the undiluted test item and of 1% (w/v) aqueous mixtures of the test item was measured using a 906 Titrando (Metrohm, Herisau, Switzerland).

The pH of the test item was 6.5.

The pH of the 1% (w/v) aqueous mixtures was 4.7.