Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
activated sludge respiration inhibition testing
Type of information:
(Q)SAR
Adequacy of study:
key study
Study period:
Not applicable, calculated value
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Remarks:
This summary has a reliability of 2 because the results are estimated using a computer model that is appropriate for use with this hydrocarbon substance.
Justification for type of information:
QSAR prediction: See Petrorisk Assessment report
Qualifier:
no guideline followed
Principles of method if other than guideline:
The aquatic toxicity was estimated by a QSAR, the Petrotox computer model (PETROTOX-UDM_ver3.01-2006-01438-01-E). This model combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components with the Target Lipid Model used to calculate acute and chronic toxicity of non-polar narcotic chemicals. Petrotox computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partition coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.
GLP compliance:
no
Remarks:
The data were calculated by a computer model
Analytical monitoring:
not required
Vehicle:
no
Test organisms (species):
other: Tetrahymena elliotti
Test type:
other: QSAR modeled data
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h
Key result
Duration:
48 h
Dose descriptor:
other: EL50
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth inhibition
Validity criteria fulfilled:
yes
Conclusions:
The hydrocarbons, C11-C16, n-alkanes, isoalkanes, <2% aromatics, estimated protozoan, Tetrahymena elliotti, 48-hr EL50 value is >1000 mg/L based on growth inhibition.
Executive summary:

The aquatic toxicity was estimated using the Petrotox computer model (PETROTOX-UDM_ver3.01-2006-01438-01-E), which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of non-polar narcotic chemicals. Petrotox computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partition coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.

The hydrocarbons, C11-C16, n-alkanes, isoalkanes, <2% aromatics, estimated protozoan, Tetrahymena elliotti, 48-hr EL50 value is >1000 mg/L based on growth inhibition.

Description of key information

The substance is not toxic to microorganisms: the estimated EC50 for Hydrocarbons, C11-C16, n-alkanes, isoalkanes, <2% aromatics is greater than 1000 mg/L.

Key value for chemical safety assessment

Additional information

The Hydrocarbons, C11-C16, n-alkanes, isoalkanes, <2% aromatics, estimated protozoan, Tetrahymena elliotti, 48-hr EL50 value is >1000 mg/L based on growth inhibition.