Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 941-474-7 | CAS number: -
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The ready biodegradability of the test item, TM 11-212 (FRET 08-0334) was assessed and attained 60% biodegradation after 28 days according to OECD Test Guideline 301D using the closed bottle method and can therefore be considered to be readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable but failing 10-day window
Additional information
Two studies were performed to investigate the ready biodegradability of the test item in the presence of unacclimatized sewage sludge micro-organisms.
The first study was performed according to OECD Test Guideline 301F - Manometric Respirometre Test method. The ready biodegradability of TM 11-212 was determined with unacclimatised sewage micro-organisms by measuring the amount of oxygen consumed over the 28-day test period. The test item was adsorbed onto a glass fibre filter and then added to test vessels at a level of 33.3 mg/L (equivalent to 96.8 mg ThOD/L) (n=2). The percentage biodegradation of TM 11-212 after 2 days averaged 29.0% (n=2), which was the initial day on which 10% biodegradation was exceeded, and when the 10-day window began. The percentage biodegradation in activated sludge averaged 64.8% (n=2) within 10-day window (after 12 days), and 76.7% after 28 days. The test item, TM 11-212 met criteria for "ready biodegradability" under the test conditions.
The second test was performed according to OECE Test Guideline 301D - Closed Bottle method. An amount of test item (0.65 μL) was dispensed onto a filter paper and added to the test vessel containing inoculated mineral medium to give a test concentration of 2.0 mg/L. The test item attained 60% biodegradation after 28 days and can therefore be considered to be readily biodegradable. The test item failed to meet the 10-Day window validation criterion, whereby 60% biodegradation must be attained within 10 days of the biodegradation exceeding 10%. However, in accordance with the Revised Introduction to the OECD Guidelines for Testing of Chemicals, Section 3, Paragraph 43 (Page 8), if testing on a complex mixture is performed, and it is anticipated that a sequential biodegradation of the individual structures takes place, then the 10-Day window should not be applied to interpret the results of the test.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
