Registration Dossier
Registration Dossier
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EC number: 940-591-0 | CAS number: -
Toxicological Summary
Administrative data
Workers - Hazard via inhalation route
Systemic effects
Acute/short term exposure
DNEL related information
Local effects
Acute/short term exposure
DNEL related information
Workers - Hazard via dermal route
Systemic effects
Acute/short term exposure
DNEL related information
Workers - Hazard for the eyes
Additional information - workers
The available data suggest no acute or chronic, oral or dermal effects of slags. From mutagenicity studies and despite the widespread use of slags, no CMR potential or other health effect of slags is identified.
The only critical exposure pathway to humans is the inhalation of the dust of fine-grained slags. Therefore exposure by inhalation is considered to be relevant as a threshold mode of action for workers and the general population.
GGBS has been chosen as a representative for the due to its elemental composition and its high fine particle content. Inhalation tests have demonstrated the absence of acute toxicity on vertebrates.
For GGBS a subacute inhalation study (according OECD TG) is planned. Thus, at the moment no scientifically based NOAEC can be derived.
However, the dust limit values - eight hours for inhalable dust are 10 mg/m³ in the European countries which have one and for respirable dust between 3 and 6 mg/m³. Those general dust limits covers all potential effects of inert dusts. The dust limit values of 10 mg/m³ (inhalable dust) and 3 mg/m³ (respirable dust) will therefore be used as DNEL’s for chronic exposure for the whole group.
General Population - Hazard via inhalation route
Systemic effects
Acute/short term exposure
DNEL related information
Local effects
Acute/short term exposure
DNEL related information
General Population - Hazard via dermal route
Systemic effects
Acute/short term exposure
DNEL related information
General Population - Hazard via oral route
Systemic effects
Acute/short term exposure
DNEL related information
General Population - Hazard for the eyes
Additional information - General Population
Exposure of the general population to slags is only incidental.
There are several methods applied to decrease the potential exposure of the general population to ferrous slags e.g.
covering e.g. in road construction by the surface layer of the road
inclusion in matrix e.g. use of slags in asphalt or concrete
reduction of dusting behaviour by e.g. wetting or pelettization
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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