Registration Dossier
Registration Dossier
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EC number: - | CAS number: 1374859-51-4
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Read-across was used. Hypothesis for the analogue approach: see files attached under section 13 assessment reports Read Across Justification. Test for source substance to partition coefficient was performed compliant with GLP.
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
- Year:
- 1 996
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: calculation method was used .
- GLP compliance:
- yes
- Type of method:
- other: calculation method
- Partition coefficient type:
- octanol-water
Test material
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
Constituent 1
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- ca. 14.5
- Temp.:
- 20 °C
- pH:
- 7
- Remarks on result:
- other: The calculated values are in a range of 5.5 to 25. The Log Pow of the main component is 14.5.
Applicant's summary and conclusion
- Conclusions:
- The partition coefficient of test substance was calculated in a range of 5.5 to 25. Log Pow of main constituent was calculated to be ca. 14.5 at 20°C. The tested substance (source substance) bis(hydrogenated tallow C16-C18-alkyl)hydroxylamine is a structurally very similar substance to target substance hydroxylamines, di-C16-18 (even numbered) alkyl. It can be reasonably assumed that target substance has the similar partition coefficient range.
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