Registration Dossier
Registration Dossier
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EC number: 939-185-6 | CAS number: -
Dissociation constant
Administrative data
Link to relevant study record(s)
- Endpoint:
- dissociation constant
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 23 September - 16 November 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 112 (Dissociation Constants in Water)
- Deviations:
- no
- GLP compliance:
- yes
- Specific details on test material used for the study:
- - Analytical purity: 94.55 %
- Expiration date: 31 December 2017
- Storage condition: at room temperature - Dissociating properties:
- yes
- pKa:
- 4.19
- Temp.:
- 25 °C
- Remarks on result:
- other: mean value of two measurements
- Conclusions:
- The dissociation constant of the substance was determined to be 4.19 at 25°C.
Reference
Two tests were performed, the mean test temperature was 20°C, and the pH meter automatically adjusts to 25°C. The mean pKa at 25°C was 4.19 (mean of 4.27 and 4.10) using the second derivative.
Description of key information
In a GLP study (K1, Foster, 2016) according to the OECD guideline 112, the dissociation constant of the test substance is determined to be 4.19 at 25°C.
Key value for chemical safety assessment
Additional information
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