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Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

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Reference
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008-10-15 to 2008-11-13
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, non-adapted
Duration of test (contact time):
28 d
Initial conc.:
108 mg/L
Based on:
test mat.
Parameter followed for biodegradation estimation:
CO2 evolution
Reference substance:
benzoic acid, sodium salt
Remarks:
at 20 mg/L
Parameter:
% degradation (CO2 evolution)
Value:
83 - 86
Sampling time:
28 d
Details on results:
Lag time was 1.5 d, Degradation time was 13.5 d, 10d window achieved (10% at day 1.5 and 60% at day 8)
Results with reference substance:
validity criteria was met based on degradation curve

In a toxicity test containing both the test item and the reference item >25% biodegradation was achieved within 14d and 84% after 28d. This means that the test item is not inhibitory.

Validity criteria fulfilled:
yes
Interpretation of results:
readily biodegradable
Executive summary:

The biodegradability of the test item Hostapon SG (24,6% a.i. SCG) was investigated in an OECD 301B ready test with non-adapted inoculum over a period of 28d. The initial test item concentration was 108 mg/L. 83 -86% Biodegradation was achieved after 28d. The 10% level of degradation was reached after 1.5d and the 60% pass level after 8d. In a toxicity test with the reference substance sodium benzoate it was demonstrated that the test item in not inhibitory.

Based on the results given before the test item Hostapon SG is readily biodegradable fulfilling the 10d window.

Description of key information

The biodegradability of the the registered substance (24,6% a.i. SCG) was investigated in an OECD 301B ready test with non-adapted inoculum over a period of 28d. The initial test item concentration was 108 mg/L. 83 -86% Biodegradation was achieved after 28d. The 10% level of degradation was reached after 1.5d and the 60% pass level after 8d. In a toxicity test with the reference substance sodium benzoate it was demonstrated that the test item in not inhibitory.

Based on the results given before the the registered substance is readily biodegradable fulfilling the 10d window.

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information