Poly[oxy(methyl-1,2-ethanediyl)], .alpha.-[2-[bis(phosphonomethyl)amino]methylethyl]-.omega.-[2-[bis(phosphonomethyl)amino]methylethoxy]-, sodium salt (1:?)

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

Testing was conducted between 15 June 2011 and 20 December 2011.

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results. The study report was conclusive, done to a valid guideline and the study was conducted under GLP conditions.

Qualifier:

equivalent or similar to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Deviations:

no

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

thermal analysis

Remarks:

differential scanning calorimetry (DSC)

Key result

Decomposition:

yes

Decomp. temp.:

ca. 119 °C

Sublimation:

no

Remarks on result:

not determinable

Remarks:

The test item has been determined to decompose from approximately 119°C (392 K) without melting.

Results

Thermograms for Determinations 1 and 2 are shown in Figure 5.1 and Figure 5.2 (see attachment 1 in attached background material).

Visual determination

The test item was observed to change in colour from a cream powder to a grey solid from approximately 119°C (392 K), indicative of decomposition.

Conclusions:

Visual assessment of the melting temperature, determined using a metal blcok apparatus, indicated that the test item has been determined to decompose from approximately 119°C (392 K) without melting.

Executive summary:

The determination was carried out by differential scanning calorimetry (DSC) using the procedure specified in ASTM E537-86 and a procedure using a capillary in a metal block device, designed to be compatible with Method A1 Melting/Freezing Temperature of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 102 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

The test item has been determined to decompose from approximately 119°C (392 K) without melting.

Description of key information

The test item has been determined to decompose from approximately 119°C (392 K) without melting.

Additional information

As a result of the low rate of enthalpy change during decomposition, the temperature at which the onset of decomposition occurred could not be determined by differential scanning calorimetry (DSC).

A visual assessment of the melting temperature was determined using a metal block apparatus. A small amount of test item was ground and placed in a capillary tube fused at one end. The test item was observed to change in colour from a cream powder to a grey solid from approximately 119°C (392 K) indicative of decomposition.