Pyrimidine, 2-ethoxy-4,6-difluoro-

Guidance on Safe Use

First-aid measures

General advice: First Aid responders should pay attention to self-protection and use the recommended protective clothing (chemical resistant gloves, splash protection). If potential for exposure exists refer to Section 8 for specific personal protective equipment.

Inhalation: Move person to fresh air. If not breathing, give artificial respiration; if by mouth to mouth use rescuer protection (pocket mask, etc). If breathing is difficult, oxygen should be administered by qualified personnel. Call a physician or transport to a medical facility.

Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Obtain medical attention without delay. Wash clothing before reuse. Properly dispose of contaminated leather items, such as shoes, belts, and watchbands. Safety shower should be located in immediate work area.

Eye Contact: Wash immediately and continuously with flowing water for at least 30 minutes. Remove contact lenses after the first 5 minutes and continue washing. Obtain prompt medical consultation, preferably from an ophthalmologist. Eye wash fountain should be located in immediate work area.

Ingestion: If swallowed, seek medical attention. Do not induce vomiting unless directed to do so by medical personnel. Seek medical attention immediately. Never give anything by mouth to an unconscious person.

Most important symptoms and effects, both acute and delayed: Aside from the information found under Description of first aid measures (above) and Indication of immediate medical attention and special treatment needed (below), no additional symptoms and effects are anticipated.

Indication of immediate medical attention and special treatment needed: Maintain adequate ventilation and oxygenation of the patient. Chemical eye burns may require extended irrigation. Obtain prompt consultation, preferably from an ophthalmologist. If burn is present, treat as any thermal burn, after decontamination. No specific antidote. Treatment of exposure should be directed at the control of symptoms and the clinical condition of the patient.

Fire-fighting measures

Extinguishing Media: Water fog or fine spray. Carbon dioxide fire extinguishers. Dry chemical fire extinguishers.

Extinguishing Media to Avoid: Do not use direct water stream.

Hazardous Combustion Products: During a fire, smoke may contain the original material in addition to combustion products of varying composition which may be toxic and/or irritating. Combustion products may include and are not limited to: Carbon monoxide. Carbon dioxide. Hydrogen fluoride.

Unusual Fire and Explosion Hazards: Violent steam generation or eruption may occur upon application of direct water stream to hot liquids. Container may rupture from gas generation in a fire situation.

Advice for firefighters

Fire Fighting Procedures: Keep people away. Isolate fire and deny unnecessary entry. Do not use direct water stream. May spread fire. Move container from fire area if this is possible without hazard. Use water spray to cool fire exposed containers and fire affected zone until fire is out and danger of reignition has passed.

Special Protective Equipment for Firefighters: Wear positive-pressure self-contained breathing apparatus (SCBA) and protective fire fighting clothing (includes fire fighting helmet, coat, trousers, boots, and gloves). If protective equipment is not available or not used, fight fire from a protected location or safe distance.

Accidental release measures

Personal precautions, protective equipment and emergency procedures: Isolate area. Keep unnecessary and unprotected personnel from entering the area. Keep upwind of spill. Ventilate area of leak or spill. Eliminate all sources of ignition in vicinity of spill or released vapor to avoid fire or explosion. Ground and bond all containers and handling equipment. Vapor explosion hazard. Keep out of sewers. Use appropriate safety equipment.

Environmental precautions: Prevent from entering into soil, ditches, sewers, waterways and/or groundwater

Methods and materials for containment and cleaning up: Contain spilled material if possible. Absorb with materials such as: Sand. Vermiculite. Collect in suitable and properly labeled containers.

Handling and storage

Risk Management Measures: This substance is handled under Strictly Controlled Conditions in accordance with REACH Regulation Article 17(3) for on-site isolated intermediates and ECHA Guidance on Intermediates, version 2-December 2010 (Reference: ECHA-2010-G-17-EN). The substance is synthesised only in one site in the EU, with the Manufacturer and the User being the same legal entity. Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at the manufacturing and use site.

General Handling: Do not get in eyes, on skin, on clothing. Wash thoroughly after handling. Do not swallow. Do not breathe vapor. Use with adequate ventilation. Keep container closed. Keep away from heat, sparks and flame. No smoking, open flames or sources of ignition in handling and storage area. Containers, even those that have been emptied, can contain vapors. Do not cut, drill, grind, weld, or perform similar operations on or near empty containers. Vapors are heavier than air and may travel a long distance and accumulate in low lying areas. Ignition and/or flash back may occur. Use of non-sparking or explosion-proof equipment may be necessary, depending upon the type of operation.

Storage: Store in original container.

Transport information

Shipping

SpecialProvisions

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

Shipping

Remarks

Shipping

Remarks

SpecialProvisions

Exposure controls / personal protection

Risk Management Measures: This substance is handled under Strictly Controlled Conditions in accordance with REACH Regulation Article 17(3) for on-site isolated intermediates and ECHA Guidance on Intermediates, version 2-December 2010 (Reference: ECHA-2010-G-17-EN). The substance is synthesised only in one site in the EU, with the Manufacturer and the User being the same legal entity. Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at the manufacturing and use site.

Personal Protection

Eye/Face Protection: Use chemical goggles. Eye wash fountain should be located in immediate work area.

Skin Protection: Use protective clothing chemically resistant to this material. Selection of specific items such as face shield, boots, apron, or full body suit will depend on the task. Use chemical protective clothing resistant to this material, when there is any possibility of skin contact. Safety shower should be located in immediate work area.

Hand protection: Use gloves, chemically resistant to this material, at all times.

Respiratory Protection: Respiratory protection should be worn when there is a potential to exceed the exposure limit requirements or guidelines. If there are no applicable exposure limit requirements or guidelines, use an approved respirator. Selection of air-purifying or positive-pressure supplied-air will depend on the specific operation and the potential airborne concentration of the material. For emergency conditions, use an approved positive-pressure self-contained breathing apparatus. In confined or poorly ventilated areas, use an approved self-contained breathing apparatus or positive pressure air line with auxiliary self-contained air supply. The following should be effective types of air-purifying respirators: Organic vapor cartridge.

Ingestion: Avoid ingestion of even very small amounts; do not consume or store food or tobacco in the work area; wash hands and face before smoking or eating.

Engineering Controls

Ventilation: Use engineering controls to maintain airborne level below exposure limit requirements or guidelines. If there are no applicable exposure limit requirements or guidelines, use only in enclosed systems or with local exhaust ventilation. Exhaust systems should be designed to move the air away from the source of vapor/aerosol generation and people working at this point. Lethal concentrations may exist in areas with poor ventilation.

Stability and reactivity

Reactivity: No dangerous reaction known under conditions of normal use.

Chemical stability: Stable.

Possibility of hazardous reactions: Not likely to occur.

Conditions to Avoid: Exposure to elevated temperatures can cause product to decompose.

Incompatible Materials: None known.

Hazardous decomposition products: Decomposition products depend upon temperature, air supply and the presence of other materials. Decomposition products can include and are not limited to: Carbon monoxide. Carbon dioxide. Hydrogen fluoride.

Disposal considerations

Waste treatment methods: Do not contaminate ponds, waterways or ditches with product, product wastes, or empty product container. Use extreme caution when disposing excess pesticide wastes or containers. Do not re-use containers for any purpose. If wastes and/or containers cannot be disposed according to label instructions, contact your local or area regulatory authorities for proper disposal procedures.